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6 Diseases Researched for Exosomes
NameACCKFocus
Alzheimer's Disease110Locked
Cancers: All12Locked
Leukemia: Chronic myelogenous leukemia (CML) 12Locked
Melanoma12Locked
Breast Cancer11Locked
Pancreatic Cancer11Locked
2 Substances Researched for Exosomes
NameACCKFocus
Breast Milk 110Locked
Curcumin34Locked
5 Pharmacological Actions Researched for Exosomes
NameACCKFocus
Antiproliferative 12Locked
Apoptotic12Locked
MicroRNA modulator12Locked
Vascular Endothelial Growth Factor Inhibitors12Locked
Antineoplastic Agents11Locked

View the Evidence:
28 Abstracts with Exosomes Research

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Immune-related microRNAs are abundant in breast milk exosomes.Dec 31, 2011

Pubmed Data : Int J Biol Sci. 2012 ;8(1):118-23. Epub 2011 Nov 29. PMID: 22211110
Article Published Date : Dec 31, 2011
Study Type : Human Study
Additional Links
Substances : Breast Milk
Additional Keywords : Exosomes
[+]

These results show that liver-derived exosomes play a pivotal role in the accumulation of T follicular regulatory cells.Jul 26, 2017

Pubmed Data : Hepatology. 2017 Jul 27. Epub 2017 Jul 27. PMID: 28749570
Article Published Date : Jul 26, 2017
Study Type : Human Study
Additional Links
Diseases : Hepatitis C
Additional Keywords : Exosomes
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This study found that exosomal transcription factors were diminished 2-10 years before clinical diagnosis of Alzheimer's disease.Jun 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ann Clin Transl Neurol. 2015 Jul ;2(7):769-73. Epub 2015 May 13. PMID: 26273689
Article Published Date : Jun 30, 2015
Study Type : Human Study
Additional Links
Diseases : Alzheimer's Disease
Additional Keywords : Exosomes
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Influenza viral particles (virions) share remarkable features with exosomes, and in large part are derived by co-opting and using host cellular machinery for their production. Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nat Commun. 2014 ;5:4816. Epub 2014 Sep 16. PMID: 25226414
Article Published Date : Dec 31, 2013
Study Type : Human In Vitro
Additional Links
Additional Keywords : Exosomes, Virion-Exosome Link
[+]

Curcumin treated animals had a significant reduction in tumor growth as measured by the decrease in size of the subcutaneous xenografts compared to untreated animals.Jun 07, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2015 Jun 8. Epub 2015 Jun 8. PMID: 26116834
Article Published Date : Jun 07, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Leukemia: Chronic myelogenous leukemia (CML)
Pharmacological Actions : Antiproliferative , Apoptotic, MicroRNA modulator, Vascular Endothelial Growth Factor Inhibitors
Additional Keywords : Exosomes
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Exposure to cancer exosomes altered the gene expression in the normal cells of mice. Dec 31, 2008

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2009 ;4(4):e5219. Epub 2009 Apr 17. PMID: 19381331
Article Published Date : Dec 31, 2008
Study Type : Animal Study
Additional Links
Diseases : Melanoma
Additional Keywords : Disease Progression, Exosomes, Tumor Associated Antigens
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Pancreatic cancer-derived exosomes promote tumor metastasis and liver pre-metastatic niche formation.Jun 27, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2017 Jun 28. Epub 2017 Jun 28. PMID: 28711943
Article Published Date : Jun 27, 2017
Study Type : Animal Study
Additional Links
Diseases : Cancer Metastasis, Pancreatic Cancer
Additional Keywords : Exosomes
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Soma-to-Germline Transmission of RNA in Mice Xenografted with Human Tumour Cells: Possible Transport by Exosomes.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2014 ;9(7):e101629. Epub 2014 Jul 3. PMID: 24992257
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Diseases : Cancers: All
Additional Keywords : Behavioral Epigenetics, Epigenetic Modification, Epigenetic Modification In Cancer, Exosomes, Transgenerational Epigenetic Modification
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The anti-inflammatory activity of orally administered L. plantarum No.14 and L. rhamnosus GG is mediated, at least in part, by circulating exosomes.Jul 21, 2017

Pubmed Data : Biochem Biophys Res Commun. 2017 Jul 22 ;489(2):248-254. Epub 2017 May 27. PMID: 28559134
Article Published Date : Jul 21, 2017
Study Type : Animal Study
Additional Links
Substances : Lactobacillus plantarum, Lactobacillus rhamnosus GG
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Exosomes
[+]

Tumor-derived exosomes and neutrophils may act cooperatively in the establishment of cancer-associated thrombosis.Jul 24, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 Jul 25 ;7(1):6438. Epub 2017 Jul 25. PMID: 28743887
Article Published Date : Jul 24, 2017
Study Type : Animal Study
Additional Links
Diseases : Breast Cancer, Cancers: All
Additional Keywords : Exosomes
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Accumulating evidence has implicated that exosomes are emerging as a novel form of intercellular communication within the nervous system.Jul 17, 2017

Pubmed Data : J Neurosci Res. 2017 Jul 18. Epub 2017 Jul 18. PMID: 28718905
Article Published Date : Jul 17, 2017
Study Type : Review
Additional Links
Diseases : Neurodegenerative Diseases
Additional Keywords : Exosomes
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Cell-derived exosomes as promising carriers for drug delivery and targeted therapy.Jul 09, 2017

Pubmed Data : Curr Cancer Drug Targets. 2017 Jul 10. Epub 2017 Jul 10. PMID: 28699500
Article Published Date : Jul 09, 2017
Study Type : Review
Additional Links
Diseases : Cancers: All
Additional Keywords : Exosomes
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Combined exosome-melatonin regimen was superior to either alone in protecting the liver against ischemia-reperfusion injury.Dec 31, 2016

Pubmed Data : Am J Transl Res. 2017 ;9(4):1543-1560. Epub 2017 Apr 15. PMID: 28469765
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Melatonin
Diseases : Liver Injury: Ischemia/reperfusion
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Matrix metalloproteinase-9 (MMP-9) inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Exosomes
[+]

Curcumin exhibits anti-breast cancer properties. Jul 01, 2007

Pubmed Data : Biochim Biophys Acta. 2007 Jul;1773(7):1116-23. Epub 2007 May 1. PMID: 17555831
Article Published Date : Jul 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Breast Cancer
Pharmacological Actions : Antineoplastic Agents
Additional Keywords : Exosomes
[+]

Exosomes as divine messengers: are they the Hermes of modern molecular oncology?Sep 18, 2014

Pubmed Data : Cell Death Differ. 2014 Sep 19. Epub 2014 Sep 19. PMID: 25236394
Article Published Date : Sep 18, 2014
Study Type : Commentary
Additional Links
Additional Keywords : Exosomes
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Exosomes derived from pancreatic cancer cells induce insulin resistance in C2C12 myotube cells.Jul 13, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 Jul 14 ;7(1):5384. Epub 2017 Jul 14. PMID: 28710412
Article Published Date : Jul 13, 2017
Study Type : In Vitro Study
Additional Links
Diseases : Insulin Resistance, Pancreatic Cancer
Additional Keywords : Exosomes
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Exosomes from Osteosarcoma and normal osteoblast differ in proteomic cargo and immunomodulatory effects on T cells.Jul 13, 2017

Pubmed Data : Exp Cell Res. 2017 Jul 14. Epub 2017 Jul 14. PMID: 28712929
Article Published Date : Jul 13, 2017
Study Type : In Vitro Study
Additional Links
Diseases : Animal Cancers, Osteosarcoma
Additional Keywords : Exosomes
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Exosomes may mediate epithelium-mesenchyme crosstalk in organ development.Jul 26, 2017

Pubmed Data : ACS Nano. 2017 Jul 27. Epub 2017 Jul 27. PMID: 28727410
Article Published Date : Jul 26, 2017
Study Type : In Vitro Study
Additional Links
Additional Keywords : Exosomes
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Extracellular Vesicles Exploit Viral Entry Routes for Cargo Delivery.May 31, 2016

Pubmed Data : Microbiol Mol Biol Rev. 2016 Jun ;80(2):369-86. Epub 2016 Mar 2. PMID: 26935137
Article Published Date : May 31, 2016
Study Type : Review
Additional Links
Additional Keywords : Exosomes, Virion-Exosome Link
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It is now clearly plausible that secreted small RNAs can regulate other types of cells through biofluids.Dec 31, 2016

Pubmed Data : Exp Biol Med (Maywood). 2017 Jan 1:1535370217723166. Epub 2017 Jan 1. PMID: 28741379
Article Published Date : Dec 31, 2016
Study Type : Review
Additional Links
Additional Keywords : Exosomes
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Macrophage exosomes as natural nanocarriers for protein delivery to inflamed brain.Jul 09, 2017

Pubmed Data : Biomaterials. 2017 Jul 10 ;142:1-12. Epub 2017 Jul 10. PMID: 28715655
Article Published Date : Jul 09, 2017
Study Type : In Vitro Study
Additional Links
Diseases : Brain Inflammation , Central Nervous System Diseases
Additional Keywords : Blood Brain Barrier, Exosomes
[+]

MSC-derived exosomes induce a significant and dose-dependent decrease in the expression and secretion of vascular endothelial growth factor.Jul 23, 2017

Pubmed Data : Cell Oncol (Dordr). 2017 Jul 24. Epub 2017 Jul 24. PMID: 28741069
Article Published Date : Jul 23, 2017
Study Type : In Vitro Study
Additional Links
Diseases : Breast Cancer
Pharmacological Actions : Angiogenesis Inhibitors, Vascular Endothelial Growth Factor Inhibitors
Additional Keywords : Exosomes
[+]

Shikonin inhibits the proliferation of human breast cancer cells by reducing tumor-derived exosomes.Jun 15, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2016 Jun 16 ;21(6). Epub 2016 Jun 16. PMID: 27322220
Article Published Date : Jun 15, 2016
Study Type : In Vitro Study
Additional Links
Substances : Shikonin
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Exosomes
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Stem cell-derived exosomes could be a promising strategy for fracture healing.Jul 24, 2017

Pubmed Data : Cell Prolif. 2017 Jul 25. Epub 2017 Jul 25. PMID: 28741758
Article Published Date : Jul 24, 2017
Study Type : Review
Additional Links
Diseases : Bone Fractures
Additional Keywords : Exosomes
[+]

The efficacy of curcumin may be enhanced in pancreatic cancer cells through exosomal facilitation.Dec 31, 2014

Pubmed Data : PLoS One. 2015;10(7):e0132845. Epub 2015 Jul 15. PMID: 26177391
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Pancreatic Cancer
Additional Keywords : Exosomes
[+]

The exosomic miR-222-3p level in sera may be a potential prognostic biomarker for predicting gemcitabine sensitivity in NSCLC patients.Jul 24, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Cancer. 2017 Jul 25 ;16(1):132. Epub 2017 Jul 25. PMID: 28743280
Article Published Date : Jul 24, 2017
Study Type : In Vitro Study
Additional Links
Diseases : Cancers: Drug Resistant, Lung Cancer
Additional Keywords : Exosomes
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This paper posits that the time is ripe to look beyond microRNA cargos and pursue innovative pathways through which dietary exosomes alter metabolism.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Genes Nutr. 2017 ;12:12. Epub 2017 Jun 22. PMID: 28694874
Article Published Date : Dec 31, 2016
Study Type : Commentary
Additional Links
Substances : Milk
Additional Keywords : Exosomes
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This review summarizes what is presently known about how exosomes are formed and released by cells.Jul 20, 2017

Pubmed Data : Cell Mol Life Sci. 2017 Jul 21. Epub 2017 Jul 21. PMID: 28733901
Article Published Date : Jul 20, 2017
Study Type : Review
Additional Links
Additional Keywords : Exosomes

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Exosomes are cell-derived vesicles that are present in many and perhaps all biological fluids, including blood, urine, and cultured medium of cell cultures. (source: Wikipedia)

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