Superiority of Natural Substances versus Drugs

Name	AC	CK
Fluoxetine (trade name Prozac)	6	60
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)	4	41
Acetaminophen	2	20
Antibiotics	2	20
Levothyroxine	2	20
Sodium Fluoride	2	20
Diclofenac	3	14
Ibuprofen	2	11
Antidepressants	1	10
Benzodiazepines	1	10
Celecoxib	1	10
Chlorhexidine gluconate	1	10
Clonazepam	1	10
Dextromethorphan	1	10
Lead	1	10
Mefenamic acid	1	10
Oseltamivir (trade name Tamiflu)	1	10
Prednisone	1	10
Glibenclamide	2	4
Metformin	2	4
Aspirin	1	2
Docusate Sodium	1	2
Pioglitazone (trade Name Actos)	1	2
Ranitidine	1	2
Sertraline	1	2
17beta-estradiol	1	1
Tamoxifen	1	1

Name	AC	CK
Depression	10	83
Dental Plaque	4	40
Dental Caries	5	32
Dysmenorrhea	3	30
Intermittent Claudication	3	30
Menopausal Syndrome	3	30
Osteoarthritis	3	30
Osteoarthritis: Knee	3	30
Diabetes Mellitus: Type 2	9	25
Chronic Pain	3	24
Anxiety Disorders	4	23
Gastroesophageal Reflux	4	22
Hypothyroidism	3	22
Gingivitis	3	21
Crohn's Disease	2	20
Fever	2	20
Generalized Anxiety Disorder	1	20
Herpes Genitalis	2	20
Hypercholesterolemia	2	20
Insomnia	2	20
Otitis media	2	20
Peripheral Neuropathies	2	20
Rheumatoid Arthritis	2	20
Inflammation	6	18
Thrombosis	5	17
High Cholesterol	4	16
Influenza A	4	14
Oxidative Stress	3	14
Pancreatic Cancer	4	14
Alzheimer's Disease	3	13
Constipation	2	12
Depression	2	12
Depressive Disorder	2	12
Gastric Ulcer	7	12
Herpes family viruses	3	12
Hyperlipidemia	2	12
Neuropathic Pain	2	12
Obesity	2	12
Osteoporosis	2	12
Acne	2	11
Candidiasis	3	11
HIV Infections	2	11
MRSA	2	11
Periodontal Diseases	2	11
Pseudomonas aeruginosa	2	11
AIDS	1	10
Anal Fissure	1	10
Aplastic Anemia	1	10
Athlete's foot	1	10
Bacterial Infections: Resistance/Biofilm Formation	1	10
Bacterial Vaginosis	1	10
Bladder Cancer	1	10
Blood Pressure: High	1	10
Breast Cancer	4	10
Burns: Severe	1	10
Cholesterol: LDL/HDL ratio	1	10
Chronic Fatigue Syndrome	1	10
Clotting	1	10
Cough	1	10
Cramp	1	10
Dandruff	1	10
Dental Caries: Children	1	10
Denture Stomatitis	1	10
Diabetes: Cardiovascular Illness	1	10
Diabetic Neuropathies	1	10
Diverticular Disease	1	10
Diverticulitis	1	10
Diverticulosis	1	10
Dyslipidemias	1	10
Dysuria	1	10
Ecchymosis	1	10
Edema	1	10
Febrile Infections	1	10
Fibrocystic Mastopathy	1	10
Fungal Infection	1	10
Gastroparesis	1	10
HIV: Opportunist Infection.	1	10
Head Lice	1	10
Headache: Migraine	1	10
Hepatitis C	1	10
Herpes Labialis	1	10
High Cholesterol: Lipoprotein (a)	1	10
Hot Flash	1	10
Hyperglycemia	5	10
IgA Nephropathy	1	10
Immune Dysregulation: TH1/TH2 imbalance	1	10
Incontinence: Fecal	1	10
Infection: Antibiotic Resistant	1	10
Influenza	1	10
Kidney Calculi	1	10
Kidney Stones	1	10
Lactation Disorders	1	10
Lead Poisoning	1	10
Liver Cancer	2	10
Lymphedema	1	10
Mastitis	1	10
Menstrual Cramps	1	10
Migraines	1	10
Perimenopausal Syndrome	1	10
Persistent	1	10
Pityriasis	1	10
Premature Ejaculation	1	10
Premenopausal Disorders	1	10
Premenstrual syndrome	1	10
Prostate Cancer	1	10
Radiation Induced Illness	1	10
Radiation Induced Illness: Dermatitis	1	10
Respiratory Infections	1	10
Rosacea	1	10
Seasonal Affective Disorder	1	10
Seborrheic Dermatitis	1	10
Smoking: Cardiovascular Disease	1	10
Staphylococcus aureus: Methicillin-resistant (MRSA)	1	10
Stomatitis: Aphthous	1	10
Tendinitis	1	10
Tendinopathy	1	10
Tendinosis	1	10
Tinea Pedis	1	10
Trigeminal Neuralgia	1	10
Upper Respiratory Infections	1	10
Urinary Tract Infections	1	10
Vaginal Discharge: Abnormal	1	10
Venous Ulcer	1	10
Warts: Common	1	10
Wound Healing	1	10
premenstrual dysphoric disorder	1	10
Pulmonary Fibrosis	5	9
Estrogen Deficiency	4	7
Lung Cancer	4	7
Arteriosclerosis	3	6
Chemotherapy-Induced Toxicity: Bleomycin	3	6
Diabetes Mellitus: Type 1	3	6
Spinal Cord Injuries	3	6
Asthma	3	5
Cardiovascular Diseases	3	5
Bone Fractures	2	4
Cancer Metastasis	2	4
Carcinoma: Non-Small-Cell Lung	2	4
Helicobacter Pylori Infection	4	4
Hyperthyroidism	2	4
Insulin Resistance	2	4
Intima Media Thickening	2	4
Melanoma	2	4
Myocardial Infarction	2	4
Pain	2	4
Stress	2	4
Triglycerides: Elevated	2	4
Advanced Glycation End products (AGE)	2	3
Arthritis	2	3
HSV-1	3	3
Lymphoma	2	3
Allergic Airway Diseases	1	2
Aortic Plaques	1	2
Arthritis: Rheumatoid	1	2
Atherosclerosis	1	2
Birth Defects	1	2
Blood Sugar Problems	1	2
Cancers: All	2	2
Cleft Lip	1	2
Colitis	1	2
Colon Cancer	2	2
Corticosteroid-Induced Toxicity	1	2
Cyanide Poisoning	1	2
Cytomegalovirus Infections	1	2
Diabetes: Lipids/Cholesterol	1	2
Ear Wax	1	2
Estrogen Dominance	2	2
Facial Nerve Diseases	1	2
Facial Paralysis	1	2
H1N1 Infection	2	2
HSV-2	2	2
Hair Loss	1	2
Heart Failure	1	2
Hepatic Steatosis	1	2
High Fructose Diet	1	2
Hyperinsulinism	1	2
Hypertension	1	2
Hypoglycemia	1	2
Immune Disorders: Low Immune Function	1	2
Leishmaniasis	1	2
Lipid Peroxidation	1	2
Lymph Node Cancer	1	2
Malaria	1	2
Melanoma: Metastatic	1	2
Memory Disorders: Drug-Induced	1	2
Metabolic Diseases	1	2
Osteopenia	1	2
Osteoporosis: Male	1	2
Osteoporosis: Steroid-Induced	1	2
Ovariectomy Associated Adverse Changes	1	2
Parasitic Diseases	1	2
Plasmodium Infections	1	2
Prostatic Hyperplasia: Benign	1	2
Radiation Induced Illness: Thoracic	1	2
Sciatica	1	2
Steroid-Induced Toxicity	1	2
Tapeworm Infection	1	2
Thyroid Diseases	1	2
Venous Thrombosis	1	2
Wound Healing: Delayed	1	2
Avian Influenza	1	1
Blood Coagulation Disorders	1	1
COPD	1	1
Candida Infection	2	1
Candidiasis: Vulvovaginal	1	1
Chemotherapy-Induced Toxicity: Doxorubicin	1	1
Chronic Obstructive Pulmonary Disease	1	1
Escherichia coli Infections	1	1
Gallstones	1	1
Gastric Cancer	1	1
Gastric Cancer: Prevention	1	1
Glioblastoma	1	1
Glioblastoma Multiforme	1	1
Gram-Negative Bacterial Infections	1	1
Gram-Positive Bacterial Infections	1	1
Hodgkin Disease	1	1
Hodgkin Lymphoma	1	1
Human Influenza	1	1
Insect Bites: Repellent	1	1
Leukemia	1	1
Lipopolysaccharide-Induced Toxicity	1	1
Lyme Disease	1	1
Oral Cancer	1	1
Proteus Vulgaris Infections	1	1
SARS	1	1
Salmonella Infections	1	1
Toxoplasma gondii Infection	1	1
Toxoplasmosis	1	1
Tumors	1	1
Yeast Infection: Vaginal	1	1

Name	AC	CK	Focus
Regional Anesthesia: Spinal	1	10

Name	AC	CK
Hypoglycemic	1	2
Ototoxic	1	2
Uterotrophic	1	1

Name	AC	CK
Policosanol	9	73
Homeopathic Medicine: All	6	60
Curcumin	13	52
Chamomile	4	42
Turmeric	4	41
Honey	4	40
St. John's Wort	4	40
Garlic	6	35
Ginger	4	33
Kava Kava	4	33
Ginkgo biloba	3	32
Vitamin B-12	3	30
Melatonin	6	27
Black Cohosh	5	26
Tea Tree	5	23
Bee Propolis	3	22
Echinacea	3	22
Anise	2	20
Green Tea	2	20
Milk Thistle	2	20
SAMe (S-adenosylmethionine)	2	20
Saffron	2	20
Solanum chrysotrichum	2	20
Thyroid Extract	2	20
Tripterygium wilfordii	2	20
Wobenzym	2	20
Cumin	4	15
Clove	4	14
Alpha-Lipoic Acid	2	12
Bitter Melon	3	12
Grapefruit Seed Extract	2	12
Propolis: Bee	2	12
Saw Palmetto	2	12
Neem	2	11
Ageratina	1	10
Arnica	1	10
Ayurvedic Formulations	1	10
Ayurvedic Medicine: Kulattha	1	10
Azelaic Acid	1	10
Betaine	1	10
Boswellia	1	10
Breast Milk	1	10
Capsaicin	1	10
Carnitine	1	10
Celery seed	1	10
Coconut Oil	1	10
Coffee	1	10
Daisy	1	10
Elderberry	1	10
Fennel	1	10
Folic Acid	1	10
Frankincense	1	10
Garlic: Aged	1	10
Grifola umbellata Mushroom	1	10
Guggul	1	10
Hirudin (from Medicinal Leaches)	1	10
Holy Basil	1	10
Homeopathic Medicine: Traumeel	1	10
Japanese Herbal Formula: Mao-to	1	10
Lactobacillus casei	1	10
Lactobacillus fermentum	1	10
Lactobacillus probiotics	1	10
Lactobacillus salivarius	1	10
Manuka Honey	1	10
Marigold	1	10
Mentha citrata	1	10
Methionine	1	10
Mistletoe	1	10
Nicotinamide adenine dinucleotide (NADH)	1	10
Pine Bark Extract	1	10
Probiotics	1	10
Psyllium	1	10
Rehmannia	1	10
Sapindus	1	10
Selenium	1	10
Senna	1	10
Theophylline	1	10
Tryptophan	1	10
Tyrosine	1	10
Vitamin B-6	1	10
Red Sage	5	9
Nigella sativa (aka Black Seed)	3	8
Grape Seed Extract	2	7
Proanthocyanidins	2	7
Artemisinin	4	6
Licorice	5	6
Peppermint	5	6
Astaxanthin	2	4
Dill	2	4
Earthworms	2	4
Fucoidan	2	4
Genistein	2	4
Noni leaf extract	2	4
Resveratrol	3	4
Thymoquinone	2	4
Vitamin C	2	4
Vitamin E	2	4
Quercetin	2	3
St. Johns Wort	2	3
Stevia	2	3
Thyme	2	3
Wormwood	2	3
Acetyl-l-carnitine	1	2
Andrographis	1	2
Antrodia camphorata	1	2
Artemisia princeps	1	2
Bacopa	1	2
Bael	1	2
Berberine	1	2
Broccoli	1	2
Bromelain	1	2
Cambucá	1	2
Cascara sagrada	1	2
Cayenne	1	2
Chaga Mushroom (Inonotus obliquus)	1	2
Chinese Herbal Formula: Decoction for Strengthening Qi and Replenishing Lung (DSQRL)	1	2
Cinnamaldehyde	1	2
Cinnamon	1	2
Dimethyl trisulfide (DMTS)	1	2
Fermented Foods and Beverages	1	2
Flaxseed	1	2
Geum japonicum	1	2
Glycyrrhizin	1	2
Gypsywort	1	2
Hawthorn	1	2
Kimchi	1	2
Kiwifruit	1	2
Moringa oleifera	1	2
Mosla scabra	1	2
Nobiletin	1	2
Noni	1	2
Olive leaf extract	1	2
Onion	1	2
Phellinus Linteus	1	2
Phyllanthus urinaria	1	2
Pineapple	1	2
Plumbum metallicum	1	2
Pomegranate Peel	1	2
Pterocarpus marsupium	1	2
Red Yeast Rice	1	2
Reishi Mushroom	1	2
Rosemary	2	2
Royal Jelly	1	2
Shikonin	1	2
Spirulina	1	2
Sumac	1	2
Tangeretin	1	2
Terminalia	1	2
Tongkat Ali	1	2
Ursolic Acid	1	2
Water: Deuterium Depleted	1	2
Yarrow	1	2
Alchornea cordifolia	1	1
Anthocyanins	1	1
Asafoetida	1	1
Bisdemethoxycurcumin	1	1
Cannabis	1	1
Chinese Skullcap	1	1
Clausena anisata	1	1
Delta-tetrahydrocannabinol (THC)	1	1
Demethoxycurcumin	1	1
EGCG (Epigallocatechin gallate)	1	1
Elaeophorbia drupifera	1	1
Eucalyptus	1	1
Feijoa	1	1
Ficus	1	1
Graviola	1	1
Haplophyllum perforatum	1	1
Heal-All	1	1
Honokiol	1	1
Huperzine	1	1
Isomangiferin	1	1
Kaempferia parviflora	1	1
Lemon Balm	1	1
Lemongrass: Essential Oil	1	1
Ligusticum wallichii	1	1
Magnolol	1	1
Mangiferin	1	1
Marijuana	1	1
Ocimum gratissimum	1	1
Omega-3 Fatty Acids	1	1
Patchouli	1	1
Pomegranate	1	1
Potato	1	1
Raspberry	1	1
Rock-rose	1	1
Sage	1	1
Sessile Joyweed	1	1
Silver (nanoparticles)	2	1
Sweet Cherry	1	1
Toona sinensis	1	1
Turmerones	1	1
Walnut	1	1

Name	AC	CK
Homeopathic Treatment	4	32
Acupuncture	3	30
Acupoint Injection	1	10
Aromatherapy	1	10
Ayurvedic Medicine	1	10
Electroacupuncture	1	10
Light Therapy	1	10
Massage/Therapeutic Touch	1	10
Placebo Effect	1	10
Weight Reduction	1	10
Yoga	1	10

Name	AC	CK
Anti-Bacterial Agents	13	76
Antidepressive Agents	7	54
Analgesics	8	50
Antioxidants	13	42
Anti-Inflammatory Agents	13	39
Antiviral Agents	9	29
Apoptotic	12	25
Anti-Ulcer Agents	7	21
Antiproliferative	9	20
Dermatologic Agents	2	20
anti-inflammatory	2	20
Antineoplastic Agents	5	19
Anticholesteremic Agents	4	16
Cyclooxygenase 2 Inhibitors	4	15
Antihypertensive Agents	3	14
Anti-Platelet	2	12
Antifungal Agents	3	12
Anxiolytic	2	12
Laxative	2	12
Tumor Necrosis Factor (TNF) Alpha Inhibitor	3	12
Prophylactic Agents	2	11
Proton Pump Inhibitor	2	11
5-alpha reductase inhibitor	1	10
Analgesics: Non-Narcotic	1	10
Anti-pyretic	1	10
Anticonvulsants	1	10
Antitussive Agents	1	10
Antiurolithiatic	1	10
Cell cycle arrest	4	10
Chelating Agents	1	10
Detoxifier	1	10
Gastrointestinal Agents	1	10
Hypoglycemic Agents	5	10
Insulin Down-Regulation	1	10
Interleukin-1 alpha downregulation	1	10
Interleukin-8 downregulation	1	10
Neuroprotective Agents	5	9
Chemopreventive	2	7
Hypolipidemic	3	6
Immunomodulatory	3	6
Gastroprotective	3	5
Antinoceceptive	2	4
Thrombolytic	2	4
Anti-Glycation Agents	2	3
Anticarcinogenic Agents	2	3
Antiparasitic Agents	2	3
Chemotherapeutic	2	3
Cytotoxic	2	3
NF-kappaB Inhibitor	2	3
Vascular Endothelial Growth Factor A Inhibitor	2	3
Anti-Adipogenic	1	2
Anti-metastatic	1	2
Anticholinergic	1	2
Antimalarials	1	2
Antimicrobial	2	2
Bronchodilator Agents	1	2
Cardioprotective	1	2
Cardiotonic Agents	1	2
Cyclin D1 Down-Regulation	1	2
Enzyme Activators	1	2
Epidermal growth factor receptor (EGFR) inhibitor	1	2
Hepatoprotective	1	2
Histamine Antagonists	1	2
Hypotensive	1	2
Insulin Sensitizers	1	2
Insulin-Like Growth Factor Enhancer/Upregulation	1	2
Insulin-releasing	1	2
Interferon-gamma (IFN-gamma) inducer	1	2
Interleukin-2 upregulation	1	2
Interleukin-4 upregulation	1	2
Interleukin-5 upregulation	1	2
Interleukin-6 Downregulation	1	2
Leishmanicidal	1	2
Lipolytic	1	2
Malondialdehyde Down-regulation	1	2
Matrix metalloproteinase-2 (MMP-2) inhibitor	1	2
MicroRNA modulator	1	2
P21 Activation	1	2
Pancreato Protective Agents	1	2
Selective Estrogen Receptor Modulators	1	2
Superoxide Dismutase Up-regulation	1	2
Transforming growth factor beta (TGF-β) inhibitor	1	2
Vascular Endothelial Growth Factor Regulator	1	2
apoptosis	1	2
Acetylcholinesterase Inhibitor	1	1
Anti-Anxiety Agents	1	1
Anti-HIV Agents	1	1
Anti-thrombotic	1	1
Antiprotozoal Agents	1	1
Aromatase Inhibitors	1	1
Autophagy Up-regulation	1	1
Cholinesterase Inhibitors	1	1
Dopaminergic	1	1
Insect Repellents	1	1
Matrix metalloproteinase-3 (MMP-3) inhibitor	1	1
Phosphodiesterase Inhibitors	1	1
Reverse Transcriptase Inhibitors	1	1
SIRT1 Activator	1	1
Selective estrogen enzyme modulator (SEEM)	1	1
Viral Hemagglutinin Inhibitor	1	1

[+]

Ginkgo biloba, chamomile and kava kava exhibit therapeutic potential in generalizaed anxiety disorder.Oct 15, 2010

Click here to read the entire abstract

Pubmed Data : Rev Bras Psiquiatr. 2010 Oct 15. Epub 2010 Oct 15. PMID: 20963375

Article Published Date : Oct 15, 2010

Study Type : Meta Analysis

Additional Links

Substances : Chamomile, Ginkgo biloba, Kava Kava

Diseases : Generalized Anxiety Disorder

Additional Keywords : Benzodiazepine Alternatives, Benzodiazepine Receptor Agonist, Natural Substances Versus Drugs, Superiority of Natural Substances versus Drugs

[+]

Zingiberaceae extracts are clinically effective hypoalgesic agents and the available data show a better safety profile than non steroidal anti inflammatory drugs.Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutr J. 2015 ;14:50. Epub 2015 May 14. PMID: 25972154

Article Published Date : Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Eur J Pain. 2015 Nov 19. Epub 2015 Nov 19. PMID: 26581442

Article Published Date : Nov 18, 2015

Study Type : Human Study

Additional Links

Substances : Capsaicin

Diseases : Neuropathic Pain, Peripheral Neuropathies

Pharmacological Actions : Analgesics

Additional Keywords : Superiority of Natural Substances versus Drugs

[+]

A dietary supplement containing melatonin, l-tryptophan, vitamin B6, folic acid, vitamin B12, methionine and betaine, is superior to omeprazole in treating GERD. Oct 01, 2006

Click here to read the entire abstract

Pubmed Data : J Pineal Res. 2006 Oct;41(3):195-200. PMID: 16948779

Article Published Date : Oct 01, 2006

Study Type : Human Study

Additional Links

Substances : Betaine , Folic Acid , Melatonin, Methionine, Tryptophan, Vitamin B-12, Vitamin B-6

Diseases : Gastroesophageal Reflux

Pharmacological Actions : Proton Pump Inhibitor

Additional Keywords : Superiority of Natural Substances versus Drugs

[+]

A formulation containing Frankincense and Turmeric extracts demonstrated a greater improvement in the treatment of OA than celecoxib.Oct 31, 2013

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Mol Med Rep. 2013 Nov ;8(5):1542-8. Epub 2013 Aug 29. PMID: 24002213

Article Published Date : Oct 31, 2013

Study Type : Human Study

Additional Links

Substances : Frankincense, Turmeric

Diseases : Osteoarthritis: Knee

Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors

Additional Keywords : Plant Extracts, Superiority of Natural Substances versus Drugs

Problem Substances : Celecoxib, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

[+]

Click here to read the entire abstract

Pubmed Data : Z Gastroenterol. 2001 Jan;39(1):11-7. PMID: 11215357

Article Published Date : Jan 01, 2001

Study Type : Human Study

Additional Links

Substances : Boswellia

Diseases : Crohn's Disease

Additional Keywords : Superiority of Natural Substances versus Drugs

[+]

Calendula vaginal cream appears to have been effective in the treatment of vaginal Candidiasis.Nov 22, 2016

Click here to read the entire abstract

Pubmed Data : Women Health. 2016 Nov 23:1-16. Epub 2016 Nov 23. PMID: 27880086

Article Published Date : Nov 22, 2016

Study Type : Human Study

Additional Links

Substances : Marigold

Diseases : Candidiasis: Vulvovaginal

Pharmacological Actions : Antifungal Agents

Additional Keywords : Superiority of Natural Substances versus Drugs

[+]

Clinical efficacy of Manasamitra Vataka (an Ayurveda medication) on generalized anxiety disorder with comorbid generalized social phobia: a randomized controlled study.May 31, 2012

Click here to read the entire abstract

Pubmed Data : J Altern Complement Med. 2012 Jun ;18(6):612-21. PMID: 22784349

Article Published Date : May 31, 2012

Study Type : Human Study

Click here to read the entire abstract

Pubmed Data : Complement Ther Clin Pract. 2014 Feb ;20(1):81-8. Epub 2013 Oct 9. PMID: 24439651

Article Published Date : Jan 31, 2014

Study Type : Human Study

Additional Links

Substances : Chamomile

Diseases : Premenopausal Disorders, Premenstrual Dysphoric Disorder, Premenstrual syndrome

Additional Keywords : Natural Substances Versus Chemicals, Superiority of Natural Substances versus Drugs

[+]

Curcumin is safe and efficacious in treating major depressive disorder.Jul 05, 2013

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Pubmed Data : Phytother Res. 2013 Jul 6. Epub 2013 Jul 6. PMID: 23832433

Click here to read the entire abstract

Pubmed Data : Altern Med Rev. 2004 Jun;9(2):157-79. PMID: 15253676

Article Published Date : Jun 01, 2004

Study Type : Human Study

Additional Links

Substances : Thyroid Extract

Diseases : Hypothyroidism

Additional Keywords : Superiority of Natural Substances versus Drugs

Problem Substances : Levothyroxine

[+]

Echinaforce Hotdrink is as effective as oseltamivir in the early treatment of confirmed influenza virus infections with a reduced risk of complications and adverse events.Nov 30, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Curr Ther Res Clin Exp. 2015 Dec ;77:66-72. Epub 2015 Apr 20. PMID: 26265958

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Pubmed Data : Basic Clin Pharmacol Toxicol. 2012 May ;110(5):476-81. Epub 2011 Dec 29. PMID: 22151785

Article Published Date : Apr 30, 2012

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Dent Res J (Isfahan). 2011 Dec ;8(Suppl 1):S58-63. PMID: 23372597

Article Published Date : Nov 30, 2011

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Pubmed Data : Zhong Xi Yi Jie He Xue Bao. 2008 Mar;6(3):253-7. PMID: 18334143

Article Published Date : Mar 01, 2008

Study Type : Human Study

Additional Links

Substances : Hirudin (from Medicinal Leaches)

Diseases : IgA Nephropathy

Additional Keywords : Drug: Dipyridamole, Superiority of Natural Substances versus Drugs

[+]

Holy basil was found to be equally effective in reducing periodontal indices as chlorhexidine yet with no side effects.Mar 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Article Published Date : Aug 31, 2013

Study Type : Human Study

Additional Links

Substances : Coffee, Honey

Diseases : Cough

Additional Keywords : Superiority of Natural Substances versus Drugs

Problem Substances : Prednisone

[+]

Hypericum extract is superior to fluoxetine in treating depressed patients. May 31, 2005

Click here to read the entire abstract

Pubmed Data : Int J Neuropsychopharmacol. 2005 Jun ;8(2):215-21. Epub 2004 Sep 30. PMID: 15458612

Article Published Date : May 31, 2005

Problem Substances : Antidepressants

[+]

Mistletoe extract is superior to gemcitabine in patients with inoperable locally advanced pancreatic cancer. May 01, 2005

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Pubmed Data : Anticancer Res. 2005 May-Jun;25(3B):1969-75. PMID: 16158932

Article Published Date : May 01, 2005

Study Type : Human Study

Additional Links

Substances : Mistletoe

Diseases : Pancreatic Cancer

Additional Keywords : Superiority of Natural Substances versus Drugs

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Neurexan might be an effective and well-tolerated alternative to conventional valerian-based therapies for the treatment of mild to moderate insomnia.Dec 31, 2007

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Affect Disord. 2014 Feb ;155:216-22. Epub 2013 Nov 16. PMID: 24289892

Article Published Date : Jan 31, 2014

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Pubmed Data : J Proteomics. 2010 Mar 10;73(5):951-64. Epub 2010 Jan 4. PMID: 19139781

Pubmed Data : J Clin Psychopharmacol. 2005 Oct ;25(5):441-7. PMID: 16160619

Article Published Date : Sep 30, 2005

Study Type : Human Study

Additional Links

Substances : St. John&#039;s Wort

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Phytotherapy, Plant Extracts, Superiority of Natural Substances versus Drugs

Problem Substances : Fluoxetine (trade name Prozac)

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Taking cumin cyminum L. for eight weeks among overweight subjects had the same effects of orlistat120 on weight and BMI but with beneficial effects on insulin metabolism.Mar 02, 2015

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Pubmed Data : Ann Nutr Metab. 2015 Mar 3 ;66(2-3):117-124. Epub 2015 Mar 3. PMID: 25766448

Article Published Date : Mar 02, 2015

Study Type : Human Study

Additional Links

Substances : Cumin

Diseases : Obesity, Oxidative Stress

Therapeutic Actions : Weight Reduction

Pharmacological Actions : Antioxidants, Insulin Down-Regulation

Additional Keywords : Natural Substances Versus Drugs, Superiority of Natural Substances versus Drugs

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Tea tree is an effective therapy for fluconazole-refractory oropharyngeal candidiasis. Sep 01, 2002

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Pubmed Data : HIV Clin Trials. 2002 Sep-Oct;3(5):379-85. PMID: 12407487

Article Published Date : Sep 01, 2002

Study Type : Human Study

Additional Links

Substances : Tea Tree

Diseases : AIDS, Candidiasis, Fungal Infection, HIV: Opportunist Infection. , HIV Infections

Pharmacological Actions : Antifungal Agents

Additional Keywords : Superiority of Natural Substances versus Drugs

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The effectiveness of 0.5% C. sinensis extract was more compared to 0.05% sodium fluoride and 0.2% chlorhexidine gluconate mouth rinses.Apr 30, 2015

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Pubmed Data : J Int Soc Prev Community Dent. 2015 May-Jun;5(3):218-26. PMID: 26236682

Article Published Date : Apr 30, 2015

Study Type : Human Study

Additional Links

Substances : Green Tea

Diseases : Dental Caries, Dental Caries: Children, Dental Plaque, Gingivitis

Pharmacological Actions : Anti-Bacterial Agents

Additional Keywords : Natural Substances Versus Drugs, Superiority of Natural Substances versus Drugs

Problem Substances : Chlorhexidine gluconate, Sodium Fluoride

[+]

The mushroom Grifola umbellata is superior to mitomycin C in preventing postoperative recurrence of bladder cancer. Sep 05, 2007

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Pubmed Data : Explore (NY). 2005 Jan ;1(1):33-9. PMID: 16781498

Article Published Date : Dec 31, 2004

Study Type : Human Study

Additional Links

Substances : Homeopathic Medicine: All

Diseases : Cramp, Febrile Infections, Fever

Pharmacological Actions : Anti-pyretic

Additional Keywords : Homeopathic Vs. Conventional Treatment, Natural Substances Versus Drugs, Superiority of Natural Substances versus Drugs

Problem Substances : Acetaminophen

[+]

Vitamin B12 is superior to the drug Nortriptyline in the treatment of diabetic neuropathy.Jan 01, 2009

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Pubmed Data : Int J Food Sci Nutr. 2009;60 Suppl 5:71-6. Epub 2009 Feb 11. PMID: 19212856

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2017 Jan 6 ;22(1). Epub 2017 Jan 6. PMID: 28067838

Article Published Date : Jan 05, 2017

Study Type : Human In Vitro

Additional Links

Substances : Elderberry

Diseases : Diabetes Mellitus: Type 2

Pharmacological Actions : Alpha-amylase inhibitor, Alpha-glucosidase inhibitor

Additional Keywords : Superiority of Natural Substances versus Drugs

[+]

Nigella sativa has successfully produced inhibition of growth of MCF cell lines with an equivalent potency as that of the standard cisplatin.Mar 31, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Agric Food Chem. 2007 Dec 12;55(25):10486-92. Epub 2007 Nov 16. PMID: 18004805

Article Published Date : Dec 12, 2007

Study Type : Animal Study

Additional Links

Substances : Fermented Foods and Beverages, Kimchi

Diseases : Aortic Plaques, Atherosclerosis, Intima Media Thickening

Additional Keywords : Drug: Simvastatin, Food as Medicine, Hall of Fame, Statin Alternatives, Superiority of Natural Substances versus Drugs

[+]

A water extract of the heartwood of Pterocarpus compares favorably to digoxin as a cardiotonic agent. Jun 01, 2007

Pubmed Data : Maturitas. 2005 Jun 16;51(2):177-86. PMID: 15917159

Article Published Date : Jun 16, 2005

Study Type : Animal Study

Additional Links

Substances : Black Cohosh

Diseases : Osteoporosis: Male

Additional Keywords : Superiority of Natural Substances versus Drugs

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CARI III exerted anti-cancer activity that is comparable to doxorubicin against melanoma in vivo, as well as in vitro.Dec 31, 2013

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2014 ;19(9):14383-95. Epub 2014 Sep 12. PMID: 25221864

Article Published Date : Dec 31, 2013

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Antrodia camphorata, Chaga Mushroom (Inonotus obliquus), Phellinus Linteus, Reishi Mushroom

Diseases : Melanoma

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, Chemopreventive, Cyclin D1 Down-Regulation, P21 Activation

Additional Keywords : Plant Extracts, Superiority of Natural Substances versus Drugs

[+]

Cascara sagrada does not contribute to carcinogenesis in a rat model, as does the stimulant laxative drug bisacodyl (Dulcolax). Sep 07, 2001

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Pubmed Data : Life Sci. 2001 Sep 7;69(16):1871-7. PMID: 11693267

Curcumin is superior to drug therapies for preventing scopolamine-induced memory impairment.Jan 26, 2011

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Pubmed Data : Fitoterapia. 2011 Jan 26. Epub 2011 Jan 26. PMID: 21277954

Article Published Date : Jan 26, 2011

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Memory Disorders: Drug-Induced

Additional Keywords : Superiority of Natural Substances versus Drugs

[+]

DDW in mice counteracted the behavioral, transcriptional and proliferative changes typical of the depressive-like states, which was comparable to the effects of citalopram.Jan 14, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2016 ;11(7):e0159631. Epub 2016 Aug 20. PMID: 27438015

Click here to read the entire abstract

Pubmed Data : Nippon Rinsho. 1998 Jan;56(1):156-60. PMID: 9465682

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Pubmed Data : Nig Q J Hosp Med. 2008 Oct-Dec;18(4):211-5. PMID: 19391322

Article Published Date : Oct 01, 2008

Study Type : Animal Study

Additional Links

Substances : Grapefruit Seed Extract

Diseases : Diabetes Mellitus: Type 1

Additional Keywords : Drug: Metformin, Metformin Alternatives, Natural Substances Versus Drugs, Superiority of Natural Substances versus Drugs

[+]

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Pubmed Data : Surg Neurol. 2005 Oct;64(4):355-61. PMID: 16231427

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View the Evidence: 272 Abstracts with Superiority of Natural Substances versus Drugs Research

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Ginkgo biloba, chamomile and kava kava exhibit therapeutic potential in generalizaed anxiety disorder.Oct 15, 2010

Zingiberaceae extracts are clinically effective hypoalgesic agents and the available data show a better safety profile than non steroidal anti inflammatory drugs.Dec 31, 2014

A triple antioxidant approach to the treatment of hepatitis C may be superior to traditional interferon and antiviral drug therapy. Oct 15, 1999

A black cohosh extract is equipotent to conjugated estrogens in reducing menopausal symptoms and bone markers, without adverse effects. Mar 14, 2003

A capsaicin 8% patch provided non-inferior pain relief to an optimized dose of pregabalin in peripheral neuropathic pain.Nov 18, 2015

A dietary supplement containing melatonin, l-tryptophan, vitamin B6, folic acid, vitamin B12, methionine and betaine, is superior to omeprazole in treating GERD. Oct 01, 2006

A formulation containing Frankincense and Turmeric extracts demonstrated a greater improvement in the treatment of OA than celecoxib.Oct 31, 2013

A homeopathic ointment preparation compares favorably with 1% diclofenac gel for acute symptomatic treatment of tendinopathy.Nov 01, 2005

A polyherbal formual containing Neem, Sapindus and Mentha citrata is superior to Betadine in treating lower abdominal pain, vaginal itching and dysuria in women with symptoms of abnormal vaginal discharge. Oct 01, 2009

A proprietary plant-based and homeopathic remedy is superior to conventional treatment in children with acute otitis media.Feb 01, 2004

Acupoint injection of Vit B12 has a superior therapeutic effect than the drug Carbamazepine in the treatment of trigeminal neuralgia. Sep 01, 2007

Acupuncture compares favorably to fluoxetine hcl (Prozac) in the treatment of depression, without the adverse side effects. Jul 01, 2009

Acupuncture in combination with foot massage is superior to Alprazolam in the treatment of insomnia. Oct 01, 2001

Acupuncture is more effective than doubling the proton pump inhibitor dose in controlling GERD symptoms in patients who fail standard dose proton pump inhibitors. Nov 15, 2007

Acupuncture is more effective than the drug Motilium in treating gastroparesis. Apr 01, 2007

Administration of vaginal royal jelly was effective in quality-of-life improvement of postmenopausal women. Oct 31, 2016

Ageratina pichinchensis was effective in therapeutic treatment in patients with minor recurrent aphthous stomatitis.Jun 19, 2015

Aloe Vera gel is a beneficial treatment and cost effective for patients with chronic ulcers.Apr 30, 2016

Although permethrin lotion is still effective for some people, coconut and anise spray can be a significantly more effective alternative treatment.Jan 01, 2010

An herbal combination of saffron, celery seed and anise is more effective than the drug mefenamic acid (NSAID) in relieving menstrual pain. Sep 01, 2009

Arnica is superior to steroids for reducing adverse effects, e.g. bruising, from rhinoplastic surgery. Jul 01, 2007

Aromatherapy massage on the abdomen is superior to Tylenol for alleviating menstrual pain in high school girls.Jan 01, 2012

Bitter melon is superior to the drug rosiglitazone (Avandia) in type 2 diabetic patients. May 01, 2009

Black cohosh compares favorably to fluoxetine in the treatment of postmenopausal symptoms.Feb 28, 2007

Boswellia appears superior to mesalazine in safety and efficacy in the treatment of Crohn's disease.Jan 01, 2001

Calendula vaginal cream appears to have been effective in the treatment of vaginal Candidiasis.Nov 22, 2016

Clinical efficacy of Manasamitra Vataka (an Ayurveda medication) on generalized anxiety disorder with comorbid generalized social phobia: a randomized controlled study.May 31, 2012

Comparison of the effectiveness of fennel and mefenamic acid on pain intensity in dysmenorrhoea.Apr 30, 2006

Comparison of treatment of 150 individuals with superficial burns using Honey versus silver sulphadiazine on 2 different sites of each patients, with significant improvement of honey treatment over silver.Sep 30, 2010

Consumption of Chamomile seems to be more effective than a drug in relieving the intensity of PMS associated symptomatic psychological pains.Jan 31, 2014

Curcumin is safe and efficacious in treating major depressive disorder.Jul 05, 2013

Curcumin treatment is safe and superior to drug therapy in patients with active RA.Oct 31, 2012

Desiccated thyroid extract compares favorably with levothyroxine in the treatment of hypothyroidism.Apr 30, 2013

Dessicated thyroid (Armour) has been associated with superior clinical outcomes compared to levothyroxine in the treatment of hypothyroidism. Jun 01, 2004

Echinaforce Hotdrink is as effective as oseltamivir in the early treatment of confirmed influenza virus infections with a reduced risk of complications and adverse events.Nov 30, 2015

Effects of Allium sativum (Garlic) on systolic and diastolic blood pressure in patients with essential hypertension.Aug 31, 2013

Efficacy and safety of Curcuma domestica extracts compared with ibuprofen in patients with knee osteoarthritis: a multicenter study.Dec 31, 2013

Electroacupuncture is superior to fluoxetine (Prozac) in improving the TH1/TH2 cytokine ratios in depressed patients. Sep 01, 2009

Garlic could be a suitable alternative for metronidazole in treatment of BV in those interested in herbal medicines or those affected by side effects of metronidazole.Jun 30, 2014

Garlic seems safer clinically and as effective as d-penicillamine for removing lead from the body.Apr 30, 2012

Ginger compares favorably to the drug sumatriptan for migraine headaches, but with lower side effects. May 08, 2013

Ginkgo biloba is as effective as the drug donepezil (Aricept) in improving symptoms of Alzheimers, but with less side effects. Mar 01, 2009

Grapefruit seeds are effective in treating urinary tract infections.Apr 01, 2005

Green tea mouth rinse resulted in significant reduction of colony number of salivary Streptococcus mutans and Lactobacillus which is comparable with sodium fluoride mouth rinse.Nov 30, 2011

Guggul extract is as at least as effective as tetracycline in treating nodulocystic acne. Oct 01, 1994

High-dose senna compares favorably with conventional polyethylene glycol-electrolyte lavage solution for outpatient colonoscopy preparation. Dec 01, 2005

Hirudin, a compound extracted from the saliva of medicinal leaches, is superior to the drug dipyridamole in treating immunoglobulin A nephropathy.Mar 01, 2008

Holy basil was found to be equally effective in reducing periodontal indices as chlorhexidine yet with no side effects.Mar 31, 2014

Homeopathic calendula is effective and superior to the drug trolamine in the treatment of irradiation-induced dermatitis for breast cancer.Apr 15, 2004

Honey is superior to dextromethorphan in treating nocturnal cough for coughing children.Nov 30, 2007

Honey plus coffee beats prednisone in treating symptoms of persistent, post-infectitious cough.Aug 31, 2013

Hypericum extract is superior to fluoxetine in treating depressed patients. May 31, 2005

Hypericum perforatum compares favorable to fluoxetine in the treatment of mild to moderate depression.Feb 28, 2006

Hypericum perforatum compares favorable to fluoxetine in the treatment of mild to moderate depression.Feb 28, 2006

In this comparative study, homoeopathic remedies against conventional treatments, the homoeopathic remedies had lower free of recurrence rates. Jun 30, 1997

Kava was judged to be well-tolerated and as effective as Buspirone and Opipramol in the acute treatment of out-patients suffering from Generalized Anxiety Disorder.Jan 01, 2003

L-carnitine lowers lipoprotein (a) serum levels in patients with type 2 diabetes, whereas simvastatin increases them. Oct 01, 2006

Lactobacillus is superior to Mesalazine in the long-term remission of symptomatic uncomplicated diverticular disease of the colon. May 01, 2008

Light therapy is as effective as fluoxetine (Prozac) in treating seasonal affective disorder, with fewer adverse effects. May 01, 2006

Lipid garlic extract is effective and a safe modality with good cure rates for treatment of recalcitrant multiple common warts.Aug 31, 2014

Manuka honey is superior to standard hydrogel therapy in the treatment of sloughy venous ulcers.Feb 01, 2009

Mao-to, a Japanese herbal medicine, is more effective than Oseltamivir in controlling fever due to type A influenza infection in children. Feb 01, 2007

Melatonin was superior to amitriptyline in the percentage of patients with a greater than 50% reduction in migraine frequency.May 09, 2016

Mistletoe extract is superior to gemcitabine in patients with inoperable locally advanced pancreatic cancer. May 01, 2005

Neurexan might be an effective and well-tolerated alternative to conventional valerian-based therapies for the treatment of mild to moderate insomnia.Dec 31, 2007

Nicotinamide adenine dinucleotide (NADH) compares favorably to conventional therapy for chronic fatigue syndrome.Jun 01, 2004

Patients and their physicians recorded significant improvements from homeopathic treatments leading to many previously prescribed drugs been discontinued.Dec 31, 2003

Policosanol is more effective than pravastatin on improving blood lipid profiles, platelet aggregation and endothelemia in older patients with type II hypercholesterolemia and high coronary risk. Jan 01, 2003

Policosanol is superior to Lipitor (atorvastatin) in improving blood lipid profiles and inhibiting platelet aggregation.Jan 01, 2003

Policosanol is superior to lovastatin and simvastatin in positively modulating blood lipid profiles. Mar 01, 1999

Policosanol is superior to lovastatin in patients with intermittent claudication. Jan 01, 2003

Policosanol is superior to the drug besfibrate in lowering blood lipids. Jan 01, 2000

Superiority of Natural Substances versus Drugs

View the Evidence:
272 Abstracts with Superiority of Natural Substances versus Drugs Research