There is a little known natural extract of plant waxes known as policosanol, extractable from sugar cane, yams, and beeswax, which has been giving some of the more profitable drugs on the market a biomedical beating since it was first investigated in clinical trials by the Cubans in the 1990's.
The benefits of grape seed extract in cancer are well documented, but modern medicine won't do anything with it until the mechanism of action has been found, so that it can be isolated, purified, made poisonous and owned by a single company for enormous profits.