Anti-Allergic Agents

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View the Evidence: Pharmacological Actions

Children who started taking multivitamins before age 4 have a decreased risk of sensitization to food allergens and lower rates of allergic rhinitis.

Pubmed Data : Am J Clin Nutr. 2009 Dec;90(6):1693-8. Epub 2009 Oct 28. PMID: 19864411
Article Published Date : Dec 01, 2009
Study Type : Human Study
Additional Links
Substances : Multivitamin : CK(243) : AC(22)
Diseases : Allergic Rhinitis : CK(318) : AC(40), Food Allergies : CK(420) : AC(57)
Pharmacological Actions : Anti-Allergic Agents : CK(89) : AC(38)

Pycnogenol improves allergic rhinitis symptoms when supplementation is started at least 5 weeks before the onset of the allergy season.

Pubmed Data : Phytother Res. 2010 Aug;24(8):1115-9. PMID: 20549654
Article Published Date : Aug 01, 2010
Study Type : Human Study
Additional Links
Substances : Flavonoids : CK(909) : AC(289)
Diseases : Allergic Rhinitis : CK(318) : AC(40)
Pharmacological Actions : Anti-Allergic Agents : CK(89) : AC(38)

Supplementation with probiotic Lactobacillus fermentum is beneficial in improving the extent and severity of atopic dermatitis in young children with moderate or severe disease.

Pubmed Data : Arch Dis Child. 2005 Sep;90(9):892-7. Epub 2005 Apr 29. PMID: 15863468
Article Published Date : Sep 01, 2005
Study Type : Human Study
Additional Links
Substances : Lactobacillus fermentum : CK(21) : AC(3), Probiotics : CK(2468) : AC(245)
Diseases : Atopic Dermatitis : CK(667) : AC(80), Atopic Dermatitis: Infant & Childhood : CK(170) : AC(14)
Pharmacological Actions : Anti-Allergic Agents : CK(89) : AC(38)

Bamboo extract reduces ovalbumin-induced airway inflammation and T helper 2 responses in mice.

Pubmed Data : J Ethnopharmacol. 2010 Mar 2;128(1):241-7. Epub 2010 Jan 14. PMID: 20079411
Article Published Date : Mar 02, 2010
Study Type : Animal Study
Additional Links
Substances : Bamboo : CK(45) : AC(22)
Diseases : Allergic Airway Diseases : CK(41) : AC(17), Asthma : CK(918) : AC(134), Immune Dysregulation: TH1/TH2 imbalance : CK(146) : AC(36)
Pharmacological Actions : Anti-Allergic Agents : CK(89) : AC(38)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Bovine milk fat enriched in conjugated linoleic and vaccenic acids attenuates allergic airway disease in mice.

Pubmed Data : Clin Exp Allergy. 2008 Jan;38(1):208-18. Epub 2007 Nov 13. PMID: 18005183
Article Published Date : Jan 01, 2008
Study Type : Animal Study
Additional Links
Substances : Butter : CK(55) : AC(13), CLA (Conjugated Linoleic Acid) : CK(71) : AC(27), Vaccenic acid : CK(25) : AC(9)
Diseases : Allergic Airway Diseases : CK(41) : AC(17), Allergies : CK(502) : AC(92)
Pharmacological Actions : Anti-Allergic Agents : CK(89) : AC(38)

Bromelain exerts anti-inflammatory effects in an ovalbumin-induced murine model of allergic airway disease.

Pubmed Data : Cell Immunol. 2005 Sep;237(1):68-75. Epub 2005 Dec 6. PMID: 16337164
Article Published Date : Sep 01, 2005
Study Type : Animal Study
Additional Links
Substances : Bromelain : CK(109) : AC(34)
Diseases : Allergic Airway Diseases : CK(41) : AC(17)
Pharmacological Actions : Anti-Allergic Agents : CK(89) : AC(38), Anti-Inflammatory Agents : CK(1230) : AC(433)

Buckwheat grain extract has anti-allergic properties.

Pubmed Data : Int Immunopharmacol. 2003 Jan;3(1):129-36. PMID: 12538043
Article Published Date : Jan 01, 2003
Study Type : Animal Study
Additional Links
Substances : Buckwheat : CK(48) : AC(16)
Diseases : Allergies : CK(502) : AC(92)
Pharmacological Actions : Anti-Allergic Agents : CK(89) : AC(38), Histamine Antagonists : CK(46) : AC(18)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Curcumin may have therapeutic value for controlling allergic responses resulting from exposure to allergens such as latex.

Pubmed Data : Clin Mol Allergy. 2007;5:1. Epub 2007 Jan 25. PMID: 17254346
Article Published Date : Jan 01, 2007
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(2910) : AC(1482)
Diseases : Allergies : CK(502) : AC(92), Allergy: Latex : CK(2) : AC(1)
Pharmacological Actions : Anti-Allergic Agents : CK(89) : AC(38)

Curcuminoids exhibit anti-allergy activity.

Pubmed Data : Bioorg Med Chem. 2004 Nov 15;12(22):5891-8. PMID: 15498665
Article Published Date : Nov 15, 2004
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(2910) : AC(1482), Curcuminoids : CK(2701) : AC(1520), Dihydrocurcumin : CK(2) : AC(1)
Diseases : Allergies : CK(502) : AC(92)
Pharmacological Actions : Anti-Allergic Agents : CK(89) : AC(38), Interleukin-4 downregulation : CK(37) : AC(12), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Hop extracts may be effective in the relief of symptoms of allergic rhinitis.

Pubmed Data : Biol Pharm Bull. 2006 Apr;29(4):689-92. PMID: 16595900
Article Published Date : Apr 01, 2006
Study Type : Animal Study
Additional Links
Substances : Hops : CK(51) : AC(20)
Diseases : Allergic Rhinitis : CK(318) : AC(40)
Pharmacological Actions : Anti-Allergic Agents : CK(89) : AC(38), Histamine Antagonists : CK(46) : AC(18)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Indian Oyster mushroom may be effective in the relief of symptoms of allergic rhinitis through inhibition of histamine release.

Pubmed Data : Biol Pharm Bull. 2007 Aug;30(8):1557-60. PMID: 17666820
Article Published Date : Aug 01, 2007
Study Type : Animal Study
Additional Links
Substances : Oyster Mushroom: Indian : CK(9) : AC(5)
Diseases : Allergic Rhinitis : CK(318) : AC(40)
Pharmacological Actions : Anti-Allergic Agents : CK(89) : AC(38), Histamine Antagonists : CK(46) : AC(18)

Kimchi made from fermented Ixeris sonchifolia contains compounds with anti-allergic properties.

Pubmed Data : J Microbiol Biotechnol. 2010 Jan;20(1):217-23. PMID: 20134255
Article Published Date : Jan 01, 2010
Study Type : Animal Study
Additional Links
Substances : Kimchi : CK(40) : AC(22)
Diseases : Allergies : CK(502) : AC(92), Anaphylaxis : CK(54) : AC(15), Inflammation : CK(1077) : AC(363)
Pharmacological Actions : Anti-Allergic Agents : CK(89) : AC(38)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

L-arginine may have a role in reducing airway hyperactivity.

Pubmed Data : Gen Physiol Biophys. 2008 Jun;27(2):85-91. PMID: 18645222
Article Published Date : Jun 01, 2008
Study Type : Animal Study
Additional Links
Substances : Arginine : CK(970) : AC(169)
Diseases : Allergic Airway Diseases : CK(41) : AC(17)
Pharmacological Actions : Anti-Allergic Agents : CK(89) : AC(38)

Lactoferrin decreases pollen antigen-induced allergic airway inflammation in a murine model of asthma.

Pubmed Data : Immunology. 2006 Oct;119(2):159-66. Epub 2006 Jun 26. PMID: 16800860
Article Published Date : Oct 01, 2006
Study Type : Animal Study
Additional Links
Substances : Lactoferrin : CK(118) : AC(31)
Diseases : Allergic Airway Diseases : CK(41) : AC(17), Asthma : CK(918) : AC(134), Oxidative Stress : CK(1945) : AC(710)
Pharmacological Actions : Anti-Allergic Agents : CK(89) : AC(38)

Loquat leaves have anti-allergic properties.

Pubmed Data : Immunopharmacol Immunotoxicol. 2009 Jun;31(2):314-9. PMID: 19514997
Article Published Date : Jun 01, 2009
Study Type : Animal Study
Additional Links
Substances : Loquat Leaves : CK(19) : AC(13)
Diseases : Allergies : CK(502) : AC(92), Anaphylaxis : CK(54) : AC(15)
Pharmacological Actions : Anti-Allergic Agents : CK(89) : AC(38), Histamine Antagonists : CK(46) : AC(18), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)

Loquat seed has immunomodulatory properties in allergic dermatitis.

Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2010;56(2):145-9. PMID: 20495297
Article Published Date : Jan 01, 2010
Study Type : Animal Study
Additional Links
Substances : Loquat Seeds : CK(11) : AC(6)
Diseases : Allergies : CK(502) : AC(92), Dermatitis : CK(1139) : AC(102), Immune Dysregulation: TH1/TH2 imbalance : CK(146) : AC(36)
Pharmacological Actions : Anti-Allergic Agents : CK(89) : AC(38), Immunomodulatory : CK(536) : AC(142), Interferon-gamma (IFN-gamma) inducer : CK(12) : AC(6), Interleukin-10 upregulation : CK(30) : AC(8), Interleukin-2 upregulation : CK(43) : AC(8), Interleukin-4 downregulation : CK(37) : AC(12)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Mangifera indica and mangiferin has anti-parasitic and anti-allergic activities.

Pubmed Data : Phytother Res. 2003 Dec;17(10):1203-8. PMID: 14669257
Article Published Date : Dec 01, 2003
Study Type : Animal Study
Additional Links
Substances : Mangifera indica : CK(60) : AC(34), Mangiferin : CK(42) : AC(27)
Diseases : Allergies : CK(502) : AC(92), Parasitic Diseases : CK(57) : AC(20)
Pharmacological Actions : Anti-Allergic Agents : CK(89) : AC(38), Antiparasitic Agents : CK(26) : AC(15)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216), Xanthones : CK(50) : AC(28)

Mangiferin inhibits passive cutaneous anaphylaxis reaction and pruritus in mice.

Pubmed Data : Planta Med. 2009 Oct;75(13):1415-7. Epub 2009 Jun 16. PMID: 19533581
Article Published Date : Oct 01, 2009
Study Type : Animal Study
Additional Links
Substances : Anemarrhena asphodeloides : CK(6) : AC(3), Mangiferin : CK(42) : AC(27)
Diseases : Allergies : CK(502) : AC(92), Anaphylaxis : CK(54) : AC(15), Pruritus : CK(12) : AC(2)
Pharmacological Actions : Anti-Allergic Agents : CK(89) : AC(38), NF-kappaB Inhibitor : CK(595) : AC(401), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216), Xanthones : CK(50) : AC(28)

Nano-silver may effectively reduce allergic inflammation in a mouse model of allergic rhinitis.

Pubmed Data : Clin Exp Otorhinolaryngol. 2012 Dec ;5(4):222-7. Epub 2012 Nov 13. PMID: 23205228
Article Published Date : Nov 30, 2012
Study Type : Animal Study
Additional Links
Substances : Silver (nanoparticles) : CK(14) : AC(9)
Diseases : Allergic Rhinitis : CK(318) : AC(40)
Pharmacological Actions : Anti-Allergic Agents : CK(89) : AC(38)

Onion exhibits anti-allergic, antihistaminic, anti-inflammatory, and antioxidant properties.

Pubmed Data : J Med Food. 2009 Apr;12(2):374-82. PMID: 19459740
Article Published Date : Apr 01, 2009
Study Type : Animal Study
Additional Links
Substances : Onion : CK(452) : AC(42)
Diseases : Allergies : CK(502) : AC(92)
Pharmacological Actions : Anti-Allergic Agents : CK(89) : AC(38), Anti-Inflammatory Agents : CK(1230) : AC(433), Antioxidants : CK(3653) : AC(1318), Histamine Antagonists : CK(46) : AC(18)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Peach extract inhibits mast cell-derived allergic inflammation.

Pubmed Data : Food Chem Toxicol. 2010 Jul 12. Epub 2010 Jul 12. PMID: 20633593
Article Published Date : Jul 12, 2010
Study Type : Animal Study
Additional Links
Substances : Peach : CK(4) : AC(2)
Diseases : Allergies : CK(502) : AC(92), Mast Cell: Over-Active : CK(6) : AC(4)
Pharmacological Actions : Anti-Allergic Agents : CK(89) : AC(38), Anti-Inflammatory Agents : CK(1230) : AC(433), Histamine Antagonists : CK(46) : AC(18), NF-kappaB Inhibitor : CK(595) : AC(401)

Perilla frutescens and rosmarinic acid may play a role in ameliorating allergy diseases.

Pubmed Data : Exp Biol Med (Maywood). 2011 Jan;236(1):99-106. PMID: 21239739
Article Published Date : Jan 01, 2011
Study Type : Animal Study
Additional Links
Substances : Perilla : CK(16) : AC(10), Rosmarinic acid : CK(4) : AC(2)
Diseases : Allergic Rhinitis : CK(318) : AC(40), Allergic Rhinoconjunctivitis : CK(2) : AC(1)
Pharmacological Actions : Anti-Allergic Agents : CK(89) : AC(38), Cyclooxygenase 2 Inhibitors : CK(269) : AC(169), Interleukin-1 beta downregulation : CK(177) : AC(70), Interleukin-6 Downregulation : CK(470) : AC(135), NF-kappaB Inhibitor : CK(595) : AC(401)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Propolis may be effective in the relief of symptoms of allergic rhinitis through inhibition of histamine release.

Pubmed Data : Immunopharmacol Immunotoxicol. 2009;31(4):688-93. PMID: 19874242
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Substances : Bee Propolis : CK(220) : AC(83)
Diseases : Allergic Rhinitis : CK(318) : AC(40)
Pharmacological Actions : Anti-Allergic Agents : CK(89) : AC(38), Histamine Antagonists : CK(46) : AC(18)

Resveratrol antagonizes antigen-induced contractions in the guinea pig trachea.

Pubmed Data : Pharmacol Res Commun. 1988 Dec;20 Suppl 5:79-82. PMID: 2907791
Article Published Date : Dec 01, 1988
Study Type : Animal Study
Additional Links
Substances : Resveratrol : CK(977) : AC(590)
Diseases : Allergies : CK(502) : AC(92)
Pharmacological Actions : Anti-Allergic Agents : CK(89) : AC(38)

Rose extract exhibits anti-inflammatory, anti-allergic and pain-killing activities.

Pubmed Data : J Ethnopharmacol. 2003 Nov;89(1):171-5. PMID: 14522451
Article Published Date : Nov 01, 2003
Study Type : Animal Study
Additional Links
Substances : Rose : CK(106) : AC(25)
Diseases : Allergies : CK(502) : AC(92), Inflammation : CK(1077) : AC(363), Pain : CK(616) : AC(91)
Pharmacological Actions : Analgesics : CK(372) : AC(78), Anti-Allergic Agents : CK(89) : AC(38), Anti-Inflammatory Agents : CK(1230) : AC(433)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

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