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Article Count - 101
Cumulative Knowledge - 145

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View the Evidence: Pharmacological Actions

Fucoidan extract derived from Undaria pinnatifida exhibits anti-angiogenic properties.

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Pubmed Data : Phytomedicine. 2012 Jun 15 ;19(8-9):797-803. Epub 2012 Apr 15. PMID: 22510492

Article Published Date : Jun 14, 2012

Study Type : Human In Vitro

Additional Links

Substances : Fucoidan : CK(152) : AC(72)

Pharmacological Actions : Anti-Angiogenic : CK(143) : AC(101)

3,3'-Diindolylmethane inhibits angiogenesis and the growth of transplantable human breast carcinoma in athymic mice.

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Pubmed Data : Carcinogenesis. 2005 Apr;26(4):771-8. Epub 2005 Jan 20. PMID: 15661811

Article Published Date : Apr 01, 2005

Study Type : Animal Study

Additional Links

Substances : Cruciferous Vegetables : CK(622) : AC(232)

Diseases : Breast Cancer : CK(2354) : AC(621), Breast Cancer: Metastatic : CK(82) : AC(33)

Pharmacological Actions : Anti-Angiogenic : CK(143) : AC(101), Anticarcinogenic Agents : CK(521) : AC(275)

A compound found within magnolia inhibits lymph node cancer metastasis in an animal model.

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Pubmed Data : Int J Cancer. 2009 Jun 1;124(11):2709-18. PMID: 19219913

Article Published Date : Jun 01, 2009

Study Type : Animal Study

Additional Links

Substances : Honokiol : CK(6) : AC(4), Magnolia : CK(40) : AC(11), Magnolia grandifloris (honokiol) : CK(5) : AC(3)

Diseases : Cancer Metastasis : CK(272) : AC(135), Lymph Node Cancer : CK(4) : AC(2), Lymph Node Metastasis : CK(3) : AC(2)

Pharmacological Actions : Anti-Angiogenic : CK(143) : AC(101), Apoptotic : CK(1489) : AC(1114), Vascular Endothelial Growth Factor D Inhibitor : CK(2) : AC(1)

Blueberry consumption inhibits angiogenic tumor growth and enhances the survival of mice with hemangioendothelioma.

Click here to read the entire abstract

Pubmed Data : Antioxid Redox Signal. 2009 Jan;11(1):47-58. PMID: 18817478

Article Published Date : Jan 01, 2009

Study Type : Animal Study

Additional Links

Substances : Blueberry : CK(140) : AC(39)

Diseases : Hemangioendothelioma : CK(5) : AC(2), Hemangioma : CK(6) : AC(4), Vascular Neoplasm : CK(4) : AC(3)

Pharmacological Actions : Anti-Angiogenic : CK(143) : AC(101)

Curcumin and tetrahydrocurcumin exhibit anti-cancer properties in liver cancer.

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Pubmed Data : World J Gastroenterol. 2008 Apr 7;14(13):2003-9. PMID: 18395899

Article Published Date : Apr 07, 2008

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482)

Diseases : Liver Cancer : CK(1641) : AC(266)

Pharmacological Actions : Anti-Angiogenic : CK(143) : AC(101), Antineoplastic Agents : CK(877) : AC(496)

Curcumin dispalys anti-proliferartive and anti-angiogenic properties on tumors.

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Pubmed Data : Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2010 Oct;35(10):1029-36. PMID: 21051827

Article Published Date : Oct 01, 2010

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482)

Diseases : Tumors : CK(197) : AC(110)

Pharmacological Actions : Anti-Angiogenic : CK(143) : AC(101), Anti-Proliferative : CK(55) : AC(49)

Curcumin displays therapeutic value in an animal model of irritable bowel syndrome.

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Pubmed Data : AAPS PharmSciTech. 2009;10(3):752-62. Epub 2009 Jun 3. PMID: 19495987

Article Published Date : Jan 01, 2009

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482)

Diseases : Colitis : CK(368) : AC(53), Irritable Bowel Syndrome : CK(829) : AC(66)

Pharmacological Actions : Anti-Angiogenic : CK(143) : AC(101), Anti-Inflammatory Agents : CK(1230) : AC(433)

Curcumin exhibits anti-liver cancer activity.

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Pubmed Data : Int J Pharm. 2010 Nov 15;400(1-2):211-20. Epub 2010 Sep 8. PMID: 20813175

Article Published Date : Nov 15, 2010

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482)

Diseases : Liver Cancer : CK(1641) : AC(266)

Pharmacological Actions : Anti-Angiogenic : CK(143) : AC(101), Apoptotic : CK(1489) : AC(1114)

Curcumin inhibits adenoid cystic carcinoma.

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Pubmed Data : Mol Pharmacol. 2010 Oct 19. Epub 2010 Oct 19. PMID: 20959361

Article Published Date : Oct 19, 2010

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482)

Diseases : Adenoid cystic carcinoma (ACC) : CK(2) : AC(1)

Pharmacological Actions : Anti-Angiogenic : CK(143) : AC(101)

Curcumin inhibits ascites tumor growth in mice.

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Pubmed Data : Mol Cell Biochem. 2005 May;273(1-2):57-67. PMID: 16013440

Article Published Date : May 01, 2005

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482)

Diseases : Tumors : CK(197) : AC(110)

Pharmacological Actions : Anti-Angiogenic : CK(143) : AC(101), Antiproliferative : CK(1052) : AC(775), Apoptotic : CK(1489) : AC(1114), NF-kappaB Inhibitor : CK(595) : AC(401), Vascular Endothelial Growth Factor A Inhibitor : CK(102) : AC(58)

Curcumin inhibits experimental collitis via anti-angiogenic and anti-inflammatory properties.

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Pubmed Data : J Pharm Pharmacol. 2009 Mar;61(3):311-21. PMID: 19222903

Article Published Date : Mar 01, 2009

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482)

Diseases : Colitis : CK(368) : AC(53)

Pharmacological Actions : Anti-Angiogenic : CK(143) : AC(101), Anti-Inflammatory Agents : CK(1230) : AC(433)

Curcumin inhibits tumor growth and angiogenesis in glioblastoma xenografts.

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Pubmed Data : Mol Nutr Food Res. 2010 Aug;54(8):1192-201. PMID: 20087857

Article Published Date : Aug 01, 2010

Study Type : Transgenic Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482)

Diseases : Glioblastoma : CK(46) : AC(20)

Pharmacological Actions : Anti-Angiogenic : CK(143) : AC(101), Anticarcinogenic Agents : CK(521) : AC(275), Antiproliferative : CK(1052) : AC(775), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(153) : AC(71)

Curcumin is an in vivo inhibitor of angiogenesis.

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Pubmed Data : Mol Med. 1998 Jun;4(6):376-83. PMID: 10780880

Article Published Date : Jun 01, 1998

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482)

Pharmacological Actions : Anti-Angiogenic : CK(143) : AC(101), Antineoplastic Agents : CK(877) : AC(496), Enzyme Inhibitors : CK(372) : AC(208), Vascular Endothelial Growth Factor A Inhibitor : CK(102) : AC(58), Vascular Endothelial Growth Factor Regulator : CK(28) : AC(12)

Curcumin may have beneficial anti-angiogenic and protective properties in kidneys of diabetics.

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Pubmed Data : J Med Assoc Thai. 2010 Feb;93 Suppl 2:S1-8. PMID: 21302394

Article Published Date : Feb 01, 2010

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482)

Diseases : Diabetes: Kidney Function : CK(75) : AC(22)

Pharmacological Actions : Anti-Angiogenic : CK(143) : AC(101), Renoprotective : CK(191) : AC(90)

Curcumin potentiates the antitumor effects of gemcitabine in an animal model of human bladder cancer through suppression of proliferative and angiogenic biomarkers.

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Pubmed Data : Biochem Pharmacol. 2010 Jan 15;79(2):218-28. Epub 2009 Aug 12. PMID: 19682434

Article Published Date : Jan 15, 2010

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482)

Diseases : Bladder Cancer : CK(186) : AC(60)

Pharmacological Actions : Anti-Angiogenic : CK(143) : AC(101), Antiproliferative : CK(1052) : AC(775)

Additional Keywords : Drug: Gemcitabine : CK(36) : AC(13), Drug Synergy : CK(327) : AC(147)

Curcumin works synergistically with oxaliplatin to inhibit colorectal cancer.

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Pubmed Data : Prostate. 2002 May 15;51(3):211-8. PMID: 17431105

Article Published Date : May 15, 2002

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482)

Diseases : Colorectal Cancer : CK(877) : AC(321)

Pharmacological Actions : Anti-Angiogenic : CK(143) : AC(101), Antineoplastic Agents : CK(877) : AC(496), Apoptotic : CK(1489) : AC(1114), Drug synergy : CK(51) : AC(12)

Additional Keywords : Drug Synergy : CK(327) : AC(147)

Dietary walnuts inhibit colorectal cancer growth in mice by suppressing angiogenesis.

Click here to read the entire abstract

Pubmed Data : Nutrition. 2011 Jul 26. Epub 2011 Jul 26. PMID: 21795022

Article Published Date : Jul 26, 2011

Study Type : Animal Study

Additional Links

Substances : Walnut : CK(163) : AC(26)

Diseases : Cancer Metastasis : CK(272) : AC(135), Colorectal Cancer : CK(877) : AC(321)

Pharmacological Actions : Anti-Angiogenic : CK(143) : AC(101)

Edible berries and wild blueberry demonstrate anti-angiogenic properties in a model of hemangioma.

Click here to read the entire abstract

Pubmed Data : J Pharm Pharmacol. 1992 Nov;44(11):926-8. PMID: 12782326

Article Published Date : Nov 01, 1992

Study Type : Animal Study

Additional Links

Substances : Berries: All : CK(780) : AC(199), Blueberry : CK(140) : AC(39)

Diseases : Hemangioma : CK(6) : AC(4)

Pharmacological Actions : Anti-Angiogenic : CK(143) : AC(101)

EGCG, a green tea polyphenol, inhibits growth, invasion, angiogenesis and metastasis of pancreatic cancer in vivo.

Click here to read the entire abstract

Pubmed Data : Front Biosci. 2008 Jan 1;13:440-52. PMID: 17981559

Article Published Date : Jan 01, 2008

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate) : CK(859) : AC(109), Green Tea : CK(930) : AC(294)

Diseases : Pancreatic Cancer : CK(530) : AC(168)

Pharmacological Actions : Anti-Angiogenic : CK(143) : AC(101)

EGCG, a green tea polyphenol, significantly interferes with androgen-independent prostate cancer in vivo.

Click here to read the entire abstract

Pubmed Data : Nutr Cancer. 2008;60(4):483-91. PMID: 18584482

Article Published Date : Jan 01, 2008

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate) : CK(859) : AC(109)

Diseases : Prostate Cancer : CK(998) : AC(288)

Pharmacological Actions : Anti-Angiogenic : CK(143) : AC(101), Apoptotic : CK(1489) : AC(1114)

Additional Keywords : Androgen-Independent Prostate Cancer : CK(3) : AC(2)

Elm bark exhibits anti-angiogenic activity.

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 2007 Jun 13;112(2):406-9. Epub 2007 Mar 12. PMID: 17428629

Article Published Date : Jun 13, 2007

Study Type : Animal Study

Additional Links

Substances : Elm tree : CK(15) : AC(5)

Pharmacological Actions : Anti-Angiogenic : CK(143) : AC(101)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Emodin exerts anti-metastatic activity in pancreatic cancer both in vitro and in vivo.

Click here to read the entire abstract

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2011 Nov ;36(22):3167-71. PMID: 22375400

Article Published Date : Nov 01, 2011

Study Type : Animal Study

Additional Links

Substances : Emodin : CK(32) : AC(19)

Diseases : Cancer Metastasis : CK(272) : AC(135), Pancreatic Cancer : CK(530) : AC(168), Pancreatic Cancer: Metastatic : CK(2) : AC(1)

Pharmacological Actions : Anti-Angiogenic : CK(143) : AC(101), Anti-metastatic : CK(192) : AC(115), Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(49) : AC(30), NF-kappaB Inhibitor : CK(595) : AC(401)

Farnesiferol C, a major compounds isolated from Ferula assafoetida, exerts antiangiogenic and antitumor activity in a human lung cancer allograft model.

Click here to read the entire abstract

Pubmed Data : Mol Cancer Ther. 2010 Jan 26. Epub 2010 Jan 26. PMID: 20103598

Article Published Date : Jan 26, 2010

Study Type : Animal Study

Additional Links

Substances : Asafoetida : CK(8) : AC(5)

Diseases : Cancers: All : CK(9062) : AC(2869), Lung Cancer : CK(496) : AC(198)

Pharmacological Actions : Anti-Angiogenic : CK(143) : AC(101), Vascular Endothelial Growth Factor A Inhibitor : CK(102) : AC(58)

Grape seed extract inhibits advanced human prostate tumor growth and angiogenesis and reduces insulin-like growth factor activity.

Click here to read the entire abstract

Pubmed Data : Int J Cancer. 2004 Feb 20;108(5):733-40. PMID: 14696100

Article Published Date : Feb 20, 2004

Study Type : Animal Study

Additional Links

Substances : Grape Seed Extract : CK(168) : AC(57)

Diseases : Prostate Cancer : CK(998) : AC(288)

Pharmacological Actions : Anti-Angiogenic : CK(143) : AC(101), Anticarcinogenic Agents : CK(521) : AC(275), Antiproliferative : CK(1052) : AC(775), Apoptotic : CK(1489) : AC(1114), Insulin-Like Growth Factor Inhibition/Downregulation : CK(66) : AC(16)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Green tea inhibits mammary tumorigenesis in the SV40-induced mouse model.

Click here to read the entire abstract

Pubmed Data : Breast Cancer Res Treat. 2008 Feb;107(3):359-69. Epub 2007 May 5. PMID: 17484049

Article Published Date : Feb 01, 2008

Study Type : Animal Study

Additional Links

Substances : Green Tea : CK(930) : AC(294)

Diseases : Breast Cancer : CK(2354) : AC(621), Simian virus 40 (SV40) : CK(7) : AC(5)

Pharmacological Actions : Anti-Angiogenic : CK(143) : AC(101), Vascular Endothelial Growth Factor Regulator : CK(28) : AC(12)

Additional Keywords : Diseases that are Linked : CK(2122) : AC(270)

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Food as Medicine Model: Cultivating Health at NuGenesis Farm

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