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Article Count - 60
Cumulative Knowledge - 108

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Name	Cumulative Knowledge	Article Count	Focus Articles
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View the Evidence: Pharmacological Actions

Acetyl L-carnitine has a therapeutic effect in the symptomatic treatment of antiretroviral toxic neuropathy in patients with HIV-1 infection.

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Pubmed Data : HIV Med. 2007 May;8(4):241-50. PMID: 17461852

Article Published Date : May 01, 2007

Study Type : Human Study

Additional Links

Substances : Acetyl-l-carnitine : CK(672) : AC(38)

Diseases : HIV Drug-Induced Toxicity : CK(68) : AC(13), HIV Infections : CK(577) : AC(184), Neuropathic Pain : CK(157) : AC(24)

Pharmacological Actions : Anti-HIV Agents : CK(108) : AC(60)

American ginseng reduces oxidative stress in patients taking the antiviral medication zidovudine without altering drug pharmacokinetics.

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Pubmed Data : J Clin Pharmacol. 2008 May;48(5):599-609. Epub 2008 Mar 4. PMID: 18319359

Article Published Date : May 01, 2008

Study Type : Human Study

Additional Links

Substances : Ginseng (American) : CK(121) : AC(31), Ginsenosides : CK(48) : AC(19)

Diseases : HIV Infections : CK(577) : AC(184)

Pharmacological Actions : Anti-HIV Agents : CK(108) : AC(60), Antioxidants : CK(3653) : AC(1318), HIV Protease Inhibitors : CK(26) : AC(15)

Additional Keywords : Drug: Zidovudine : CK(11) : AC(2), Plant Extracts : CK(3572) : AC(1216)

Bitter melon appears to have therapeutic activity in the treatment of HIV infection.

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 2009 May 23. PMID: 12346831

Article Published Date : May 23, 2009

Study Type : Human Study

Additional Links

Substances : Bitter Melon : CK(65) : AC(18)

Diseases : HIV Infections : CK(577) : AC(184)

Pharmacological Actions : Anti-HIV Agents : CK(108) : AC(60)

Neem has antimalarial and anti-HIV activity.

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Pubmed Data : Toxicol In Vitro. 2009 Mar;23(2):251-8. Epub 2008 Dec 13. PMID: 15138081

Article Published Date : Mar 01, 2009

Study Type : Human Study

Additional Links

Substances : Neem : CK(88) : AC(19)

Diseases : HIV Infections : CK(577) : AC(184), Malaria : CK(55) : AC(25)

Pharmacological Actions : Anti-HIV Agents : CK(108) : AC(60), Antimalarials : CK(22) : AC(10)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Sumac (Rhus chinensis) contains compounds with anti-HIV activity - Article 3.

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Pubmed Data : J Ethnopharmacol. 2006 Apr 21;105(1-2):269-73. Epub 2005 Dec 20. PMID: 16368204

Article Published Date : Apr 21, 2006

Study Type : Human Study

Additional Links

Substances : Sumac : CK(37) : AC(16)

Diseases : HIV Infections : CK(577) : AC(184)

Pharmacological Actions : Anti-HIV Agents : CK(108) : AC(60)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Ailanthus inhibts HIV-1 fusion.

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Pubmed Data : Phytother Res. 2003 Apr;17(4):426-9. PMID: 12722157

Article Published Date : Apr 01, 2003

Study Type : Animal Study

Additional Links

Substances : Ailanthus altissima : CK(2) : AC(1)

Diseases : HIV Infections : CK(577) : AC(184)

Pharmacological Actions : Anti-HIV Agents : CK(108) : AC(60), HIV Fusion Inhibitors : CK(5) : AC(4)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Croton tiglium, Cynomorium songaricum, Xanthoceras sorbifolia, and oleanolic acid derivates exhibit anti-HIV activity.

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Pubmed Data : Yakugaku Zasshi. 2004 Aug;124(8):519-29. PMID: 15297721

Article Published Date : Aug 01, 2004

Study Type : Animal Study

Additional Links

Substances : Croton Tiglium : CK(2) : AC(1), Cynomorium songaricum : CK(5) : AC(3), Oleanolic acid : CK(7) : AC(4), Xanthoceras sorbifolia : CK(3) : AC(2)

Diseases : HIV Infections : CK(577) : AC(184)

Pharmacological Actions : Anti-HIV Agents : CK(108) : AC(60), HIV Protease Inhibitors : CK(26) : AC(15)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Phyllanthus niruri (syn. P. amarus) inhibits HIV replication in vitro and in vivo.

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Pubmed Data : Antiviral Res. 2004 Nov;64(2):93-102. PMID: 15498604

Article Published Date : Nov 01, 2004

Study Type : Animal Study

Additional Links

Substances : Phyllanthus niruri (Stonebreaker) : CK(21) : AC(9)

Diseases : HIV Infections : CK(577) : AC(184)

Pharmacological Actions : Anti-HIV Agents : CK(108) : AC(60), HIV Protease Inhibitors : CK(26) : AC(15)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

A shiitake/rice bran combination known as MGN-3 has potent anti-HIV activity.

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Pubmed Data : Biochem Biophys Res Commun. 1998 Feb 4;243(1):25-9. PMID: 9473473

Article Published Date : Feb 04, 1998

Study Type : In Vitro Study

Additional Links

Substances : Modified Arabinoxylan Rice Bran (MGN-3) : CK(2) : AC(2), Rice Bran : CK(29) : AC(14), Shiitake Mushroom : CK(24) : AC(17)

Diseases : HIV Infections : CK(577) : AC(184)

Pharmacological Actions : Anti-HIV Agents : CK(108) : AC(60)

Alpinia glanga inhibits an HIV-1 viral regulatory protein, in vitro.

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Pubmed Data : Bioorg Med Chem Lett. 2009 May 1;19(9):2555-7. Epub 2009 Mar 17. PMID: 19342232

Article Published Date : May 01, 2009

Study Type : In Vitro Study

Additional Links

Substances : Alpinia galanga : CK(5) : AC(4)

Diseases : HIV Infections : CK(577) : AC(184)

Pharmacological Actions : Anti-HIV Agents : CK(108) : AC(60)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Aqueous, as opposed to ethanol extract of Prunella vulgaris showed antiviral activity against HIV-1, primarily by inhibiting early events in the life cycle of the virus.

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Virol J. 2011 ;8:188. Epub 2011 Apr 23. PMID: 21513560

Article Published Date : Jan 01, 2011

Study Type : Plant Study

Additional Links

Substances : Prunella vulgaris. : CK(6) : AC(5)

Diseases : HIV Infections : CK(577) : AC(184)

Pharmacological Actions : Anti-HIV Agents : CK(108) : AC(60)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216), Water Versus Alcohol Extraction : CK(1) : AC(1)

Banana lectin is a potent inhibitor of HIV replication.

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Pubmed Data : J Biol Chem. 2010 Mar 19;285(12):8646-55. Epub 2010 Jan 15. PMID: 20080975

Article Published Date : Mar 19, 2010

Study Type : In Vitro Study

Additional Links

Substances : Banana : CK(123) : AC(36)

Diseases : HIV Infections : CK(577) : AC(184)

Pharmacological Actions : Anti-HIV Agents : CK(108) : AC(60), Antiviral Agents : CK(613) : AC(280)

Additional Keywords : Lectins : CK(58) : AC(36), Plant Extracts : CK(3572) : AC(1216)

Betulinic acid appears to be the predominant anti-HIV-1 constituent of Peltophorum africanum.

Click here to read the entire abstract

Pubmed Data : Tohoku J Exp Med. 2009 Feb;217(2):93-9. PMID: 19212101

Article Published Date : Feb 01, 2009

Study Type : In Vitro Study

Additional Links

Substances : Betulinic acid : CK(6) : AC(6), Peltophorum africanum : CK(1) : AC(1)

Diseases : HIV Infections : CK(577) : AC(184)

Pharmacological Actions : Anti-HIV Agents : CK(108) : AC(60)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Betulinic acid has therapeutic potential in the prevention and treatment of cancer and HIV infection.

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Pubmed Data : Med Res Rev. 2004 Jan;24(1):90-114. PMID: 14595673

Article Published Date : Jan 01, 2004

Study Type : Commentary

Additional Links

Substances : Betulinic acid : CK(6) : AC(6)

Diseases : Cancers: All : CK(9062) : AC(2869), HIV Infections : CK(577) : AC(184)

Pharmacological Actions : Anti-HIV Agents : CK(108) : AC(60), Apoptotic : CK(1489) : AC(1114)

Additional Keywords : Selective Cytotoxicity : CK(58) : AC(41)

Black and green tea contain compounds which inhibit HIV-1 entry.

Click here to read the entire abstract

Pubmed Data : Biochim Biophys Acta. 2005 May 25;1723(1-3):270-81. Epub 2005 Mar 24. PMID: 15823507

Article Published Date : May 25, 2005

Study Type : In Vitro Study

Additional Links

Substances : Black Tea : CK(158) : AC(40), Catechin : CK(403) : AC(130), Green Tea : CK(930) : AC(294)

Diseases : HIV Infections : CK(577) : AC(184)

Pharmacological Actions : Anti-HIV Agents : CK(108) : AC(60)

Black cohosh contains a compound Actein which exhibits anti-HIV activity.

Click here to read the entire abstract

Pubmed Data : Bioorg Med Chem Lett. 2004 Mar 8;14(5):1329-32. PMID: 14980692

Article Published Date : Mar 08, 2004

Study Type : In Vitro Study

Additional Links

Substances : Black Cohosh : CK(37) : AC(15)

Diseases : HIV Infections : CK(577) : AC(184)

Pharmacological Actions : Anti-HIV Agents : CK(108) : AC(60)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Brown seaweed contain fucoidans with antiretroviral activity against HIV-1, including drug-resistant strains.

Click here to read the entire abstract

Pubmed Data : Mol Pharmacol. 2004 Dec;66(6):1643-51. Epub 2004 Sep 10. PMID: 19107862

Article Published Date : Dec 01, 2004

Study Type : In Vitro Study

Additional Links

Substances : Fucoidan : CK(152) : AC(72), Seaweed: Brown : CK(49) : AC(5)

Diseases : HIV Infections : CK(577) : AC(184)

Pharmacological Actions : Anti-HIV Agents : CK(108) : AC(60)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Cacao husk lignin fractions contain anti-HIV activity.

Click here to read the entire abstract

Pubmed Data : In Vivo. 2008 May-Jun;22(3):327-32. PMID: 18610744

Article Published Date : May 01, 2008

Study Type : In Vitro Study

Additional Links

Diseases : HIV Infections : CK(577) : AC(184)

Pharmacological Actions : Anti-HIV Agents : CK(108) : AC(60)

Additional Keywords : Drug-Plant-Vitamin Synergies : CK(1011) : AC(268), Plant Extracts : CK(3572) : AC(1216)

Calophyllum brasiliense and Clusia quadrangula exhibit HIV-1 inhibitory activity, in vitro.

Click here to read the entire abstract

Pubmed Data : Curr Eye Res. 2010 Apr;35(4):335-51. PMID: 15187447

Article Published Date : Apr 01, 2010

Study Type : In Vitro Study

Additional Links

Substances : Calophyllum brasiliense : CK(4) : AC(4), Clusia quadrangula : CK(1) : AC(1)

Diseases : HIV Infections : CK(577) : AC(184)

Pharmacological Actions : Anti-HIV Agents : CK(108) : AC(60)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Calophyllum brasiliense leaves contain HIV-1 inhibitory compounds - Article 2.

Click here to read the entire abstract

Pubmed Data : Planta Med. 2002 Jan;68(1):86-7. PMID: 11842340

Article Published Date : Jan 01, 2002

Study Type : In Vitro Study

Additional Links

Substances : Calophyllum brasiliense : CK(4) : AC(4)

Diseases : HIV Infections : CK(577) : AC(184)

Pharmacological Actions : Anti-HIV Agents : CK(108) : AC(60), Reverse Transcriptase Inhibitors : CK(42) : AC(24)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216), Xanthones : CK(50) : AC(28)

Calophyllum seed oil contain coumarins with anti-HIV activity.

Click here to read the entire abstract

Pubmed Data : Bioorg Med Chem Lett. 1998 Dec 15;8(24):3475-8. PMID: 9934455

Article Published Date : Dec 15, 1998

Study Type : In Vitro Study

Additional Links

Substances : Calophyllum brasiliense : CK(4) : AC(4)

Diseases : HIV Infections : CK(577) : AC(184)

Pharmacological Actions : Anti-HIV Agents : CK(108) : AC(60), Reverse Transcriptase Inhibitors : CK(42) : AC(24)

Celastrol inhibits Tat-mediated human immunodeficiency virus (HIV) transcription and replication.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Mol Biol. 2011 Jul 29 ;410(5):972-83. PMID: 21763500

Article Published Date : Jul 28, 2011

Study Type : Review

Additional Links

Substances : Celastrol : CK(1) : AC(1), Tripterygium wilfordii : CK(95) : AC(24)

Diseases : HIV Infections : CK(577) : AC(184)

Pharmacological Actions : Anti-HIV Agents : CK(108) : AC(60)

Chrysanthemum morifolium contains a flavonoid with anti-HIV activity.

Click here to read the entire abstract

Pubmed Data : Planta Med. 2003 Sep;69(9):859-61. PMID: 14598216

Article Published Date : Sep 01, 2003

Study Type : In Vitro Study

Additional Links

Substances : Chrysanthemum Morifolium : CK(4) : AC(3), Flavonoids : CK(909) : AC(289)

Diseases : HIV Infections : CK(577) : AC(184)

Pharmacological Actions : Anti-HIV Agents : CK(108) : AC(60)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Cinnamon cassia and Cardiospermum helicacabum have significant anti-HIV activity.

Click here to read the entire abstract

Pubmed Data : Indian J Med Res. 2000 Sep;112:73-7. PMID: 11094851

Article Published Date : Sep 01, 2000

Study Type : In Vitro Study

Additional Links

Substances : Cardiospermum helicacabum : CK(1) : AC(1), Cinnamon Cassia : CK(1) : AC(1)

Diseases : HIV Infections : CK(577) : AC(184)

Pharmacological Actions : Anti-HIV Agents : CK(108) : AC(60)

Clausena excavata exhibits anti-HIV-1 activity.

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2005 Aug;19(8):728-31. PMID: 16177980

Article Published Date : Aug 01, 2005

Study Type : In Vitro Study

Additional Links

Substances : Clausena excavata : CK(3) : AC(3)

Diseases : HIV Infections : CK(577) : AC(184)

Pharmacological Actions : Anti-HIV Agents : CK(108) : AC(60)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Health Guide: HIV/AIDS Research

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