Antineoplastic Agents

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View the Evidence: Pharmacological Actions

Acupressure has therapeutic value for chemotherapy-induced nausea and vomiting.

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Pubmed Data : Oncol Nurs Forum. 2007 Jul;34(4):813-20. PMID: 17723973

Article Published Date : Jul 01, 2007

Study Type : Meta Analysis

Additional Links

Diseases : Chemotherapy-Induced Nausea : CK(70) : AC(6), Nausea : CK(50) : AC(5)

Therapeutic Actions : Acupressure : CK(293) : AC(26)

Pharmacological Actions : Antineoplastic Agents : CK(833) : AC(457)

There is evidence to support the use of topical calendula for prophylaxis of acute dermatitis during radiotherapy and Traumeel S mouthwash in the treatment of chemotherapy-induced stomatitis.

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Pubmed Data : Cochrane Database Syst Rev. 2009(2):CD004845. Epub 2009 Apr 15. PMID: 19370613

Article Published Date : Jan 01, 2009

Study Type : Meta Analysis

Additional Links

Substances : Calendula : CK(41) : AC(4), Homeopathic Medicine: All : CK(501) : AC(47), Homeopathic Medicine: Traumeel : CK(40) : AC(3)

Diseases : Breast Cancer : CK(2051) : AC(566), Cancers: All : CK(8467) : AC(2708), Chemotherapy-Induced Toxicity : CK(692) : AC(184), Dermatitis : CK(1139) : AC(102), Radiation Induced Illness : CK(1024) : AC(249), Radiation Induced Illness: Dermatitis : CK(30) : AC(2), Stomatitis: Aphthous : CK(51) : AC(6)

Pharmacological Actions : Antineoplastic Agents : CK(833) : AC(457)

Additional Keywords : Plant Extracts : CK(3401) : AC(1158)

There is no firm evidence to support or refute transarterial (chemo)embolisation for unresectable hepatocellular carcinoma. for patients with unresectable HCC.

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Pubmed Data : Cochrane Database Syst Rev. 2011(3):CD004787. Epub 2011 Mar 16. PMID: 21412886

Article Published Date : Jan 01, 2011

Study Type : Meta Analysis

Additional Links

Diseases : Liver Cancer : CK(1577) : AC(266)

Pharmacological Actions : Antineoplastic Agents : CK(833) : AC(457)

Anti Therapeutic Actions : Preoperative Transarterial Chemoembolization : CK(40) : AC(2)

Finger acupressure may decrease nausea among women undergoing chemotherapy for breast cancer.

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Pubmed Data : Oncol Nurs Forum. 2000 Jan-Feb;27(1):41-7. PMID: 10660922

Article Published Date : Jan 01, 2000

Study Type : Human Study

Additional Links

Diseases : Chemotherapy-Induced Nausea : CK(70) : AC(6)

Therapeutic Actions : Acupressure : CK(293) : AC(26)

Pharmacological Actions : Antineoplastic Agents : CK(833) : AC(457)

A proprietary honey-based herbal formula reduces chemotherapy-induced neutropenia and the need for colony-stimulating factors.

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Pubmed Data : Med Oncol. 2006;23(4):549-52. PMID: 17303914

Article Published Date : Jan 01, 2006

Study Type : Human Study

Additional Links

Substances : Honey: Life Mel Proprietary Formula : CK(220) : AC(45)

Diseases : Cancers: All : CK(8467) : AC(2708), Chemotherapy-Induced Toxicity : CK(692) : AC(184), Neutropenia : CK(90) : AC(22), Neutropenia: Chemotherapy Induced : CK(82) : AC(17)

Pharmacological Actions : Antineoplastic Agents : CK(833) : AC(457)

Additional Keywords : Colony-Stimulating Factors (CSFs) : CK(33) : AC(9)

An omega-3 fatty acid rich diet reduces toxicity of chemoradiation therapy for patients with esophageal cancer.

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Pubmed Data : Gan To Kagaku Ryoho. 2008 Mar;35(3):437-40. PMID: 18347392

Article Published Date : Mar 01, 2008

Study Type : Human Study

Additional Links

Substances : Omega-3 Fatty Acids : CK(3255) : AC(319)

Diseases : Esophageal Cancer : CK(323) : AC(55)

Pharmacological Actions : Antineoplastic Agents : CK(833) : AC(457)

Additional Keywords : Drug Side Effect Attenuation : CK(252) : AC(49)

Antineoplasto exhibits antitumor activity against malignant brain tumors.

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Article Publish Status : This is a free article. Click here to read the entire article.

Pubmed Data : Kurume Med J. 1995 ;42(3):133-40. PMID: 7474850

Article Published Date : Jan 01, 1995

Study Type : Human Study

Additional Links

Substances : Antineoplastons : CK(134) : AC(36)

Diseases : Brain Cancer : CK(229) : AC(86), Glioblastoma : CK(46) : AC(20)

Pharmacological Actions : Antineoplastic Agents : CK(833) : AC(457)

Antineoplaston A10 and AS2-1 in children with recurrent and progressive multicentric glioma compares favorably to radiation therapy and chemotherapy.

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Pubmed Data : Drugs R D. 2004 ;5(6):315-26. PMID: 15563234

Article Published Date : Jan 01, 2004

Study Type : Human Study

Additional Links

Substances : Antineoplaston AS2-1 (4:1 mixture of phenylacetic acid and phenylacetylglutamine) : CK(92) : AC(1)

Diseases : Cancers: Pediatric : CK(95) : AC(10), Glioma : CK(72) : AC(43), Glioma: Astrocytic : CK(14) : AC(2), Glioma: Progressive and Recurrent Multicentric : CK(10) : AC(1)

Pharmacological Actions : Antineoplastic Agents : CK(833) : AC(457), Chemotherapeutic : CK(35) : AC(6)

Antineoplaston A10 and AS2-1 treatment is effective and relatively safe for the long-term survival of high-risk pediatric patients with primitive neuroectodermal tumors.

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Pubmed Data : Integr Cancer Ther. 2005 Jun ;4(2):168-77. PMID: 15911929

Article Published Date : Jun 01, 2005

Study Type : Human Study

Additional Links

Substances : Antineoplaston AS2-1 (4:1 mixture of phenylacetic acid and phenylacetylglutamine) : CK(92) : AC(1)

Diseases : Cancers: Pediatric : CK(95) : AC(10), Primitive Neuroectodermal Tumors (PNETs) : CK(10) : AC(1)

Pharmacological Actions : Antineoplastic Agents : CK(833) : AC(457)

Antineoplaston AS2-1 prolongs the recurrence-free interval between regional treatments and improves survival rate of these patients.

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Pubmed Data : Oncol Rep. 2003 Mar-Apr;10(2):391-7. PMID: 12579278

Article Published Date : Mar 01, 2003

Study Type : Human Study

Additional Links

Substances : Antineoplaston AS2-1 (4:1 mixture of phenylacetic acid and phenylacetylglutamine) : CK(92) : AC(1)

Diseases : Liver Cancer : CK(1577) : AC(266)

Pharmacological Actions : Antineoplastic Agents : CK(833) : AC(457), Chemopreventive : CK(1314) : AC(355)

Caffeine potentiates chemotherapy for metastatic osteosarcoma.

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Pubmed Data : J Orthop Sci. 2009 Sep;14(5):556-65. Epub 2009 Oct 3. PMID: 19802667

Article Published Date : Sep 01, 2009

Study Type : Human Study

Additional Links

Substances : Caffeine : CK(109) : AC(18)

Diseases : Chemotherapy-Induced Toxicity: Cisplatin : CK(165) : AC(66), Lung Cancer : CK(494) : AC(198)

Pharmacological Actions : Antineoplastic Agents : CK(833) : AC(457), Chemosensitizer : CK(188) : AC(156)

Additional Keywords : Drug: Doxorubicin : CK(140) : AC(54), Drug Synergy : CK(324) : AC(144)

Children treated for solid tumors or lymphoma with chemotherapy have increased caries of the primary teeth.

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Pubmed Data : Int J Paediatr Dent. 2010 Jan;20(1):15-23. PMID: 20059589

Article Published Date : Jan 01, 2010

Study Type : Human Study

Additional Links

Diseases : Chemotherapy-Induced Toxicity : CK(692) : AC(184), Dental Caries : CK(241) : AC(32), Neuroblastoma : CK(52) : AC(31)

Pharmacological Actions : Antineoplastic Agents : CK(833) : AC(457)

Additional Keywords : Drug Side Effect Attenuation : CK(252) : AC(49)

Combination chemotherapy and chemoradiation does not improve overall survival in inoperabe advanced pancreatic cancer over single chemotherapy alone.

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Pubmed Data : Cochrane Database Syst Rev. 2009(4):CD002093. Epub 2009 Oct 7. PMID: 19821291

Article Published Date : Jan 01, 2009

Study Type : Human Study

Additional Links

Diseases : Pancreatic Cancer : CK(513) : AC(162)

Pharmacological Actions : Antineoplastic Agents : CK(833) : AC(457)

Additional Keywords : Drug: 5-flourouracil : CK(88) : AC(22), Drug: Gemcitabine : CK(36) : AC(13)

Anti Therapeutic Actions : Chemotherapy : CK(248) : AC(36)

Curcumin selectively induces programmed cell death in cutaneous T-cell lymphoma cell lines and in peripheral blood mononuclear cells (PBMCs).

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Pubmed Data : J Invest Dermatol. 2010 Aug;130(8):2110-9. Epub 2010 Apr 15. PMID: 20393484

Article Published Date : Aug 01, 2010

Study Type : Human Study

Additional Links

Substances : Curcumin : CK(2890) : AC(1511)

Diseases : T-Cell Lymphoma: Cutaneous : CK(10) : AC(1)

Pharmacological Actions : Antineoplastic Agents : CK(833) : AC(457), Antiproliferative : CK(969) : AC(725), Apoptotic : CK(1416) : AC(1089), NF-kappaB Inhibitor : CK(599) : AC(397)

Dosage Study: A daily dose of 3.6 g of curcumin engendered 62% and 57% decreases in inducible PGE(2) production in blood samples taken 1 hour after dose on days 1 and 29, respectively, in patients with advanced colorectal cancer.

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Pubmed Data : Clin Cancer Res. 2004 Oct 15;10(20):6847-54. PMID: 15501961

Article Published Date : Oct 15, 2004

Study Type : Human Study

Additional Links

Substances : Curcumin : CK(2890) : AC(1511)

Diseases : Colorectal Cancer : CK(809) : AC(303)

Pharmacological Actions : Antineoplastic Agents : CK(833) : AC(457), Prostaglandin PGE2 downregulation : CK(30) : AC(14)

Dosage Study: Turmeric extract can be administered safely to patients at doses of up to 2.2 g daily, equivalent to 180 mg of curcumin.

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Pubmed Data : Clin Cancer Res. 2001 Jul;7(7):1894-900. PMID: 11448902

Article Published Date : Jul 01, 2001

Study Type : Human Study

Additional Links

Substances : Curcumin : CK(2890) : AC(1511), Turmeric : CK(2969) : AC(1565)

Diseases : Colorectal Cancer : CK(809) : AC(303)

Pharmacological Actions : Antineoplastic Agents : CK(833) : AC(457)

Additional Keywords : Plant Extracts : CK(3401) : AC(1158)

Hyperbaric oxygen therapy may be an appropriate therapeutic regimen for the treatment of patients with osteosarcoma.

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Pubmed Data : Oncol Rep. 2009 Nov;22(5):1045-50. PMID: 19787219

Article Published Date : Nov 01, 2009

Study Type : Human Study

Additional Links

Diseases : Osteosarcoma : CK(82) : AC(40)

Therapeutic Actions : Hyperbaric Treatment : CK(297) : AC(32)

Pharmacological Actions : Antineoplastic Agents : CK(833) : AC(457), Antiproliferative : CK(969) : AC(725), Apoptotic : CK(1416) : AC(1089)

Additional Keywords : Drug Synergy : CK(324) : AC(144)

Intensive treatment strategies may not provide superior outcomes in mantle cell lymphoma.

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Pubmed Data : Ann Oncol. 2008 Jul ;19(7):1327-30. Epub 2008 Mar 17. PMID: 18349031

Article Published Date : Jul 01, 2008

Study Type : Human Study

Additional Links

Diseases : Lymphoma: Mantle Cell : CK(35) : AC(8)

Pharmacological Actions : Antineoplastic Agents : CK(833) : AC(457)

Additional Keywords : Drug: Doxorubicin : CK(140) : AC(54)

Anti Therapeutic Actions : Chemotherapy : CK(248) : AC(36)

Problem Substances : Chemotherapy : CK(345) : AC(44)

Lycopene and soy isoflavones have activity in prostate cancer patients with PSA relapse disease and may delay progression of both hormone-refractory and hormone-sensitive prostate cancer.

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Pubmed Data : J Pharm Pharmacol. 2009 Jul;61(7):961-7. PMID: 17927495

Article Published Date : Jul 01, 2009

Study Type : Human Study

Additional Links

Substances : Carotenoids : CK(1055) : AC(213), Genistein : CK(436) : AC(174), Isoflavones : CK(627) : AC(124), Lycopene : CK(194) : AC(38)

Diseases : Prostate Cancer : CK(956) : AC(288)

Pharmacological Actions : Antineoplastic Agents : CK(833) : AC(457)

Pycnogenol may alleviate adverse effects in oncologic treatment, e.g. deep vein thrombosis.

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Pubmed Data : Mol Vis. 2008;14:1288-92. Epub 2008 Jul 10. PMID: 18927527

Article Published Date : Jan 01, 2008

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(868) : AC(290), Pycnogenol : CK(500) : AC(55)

Diseases : Chemotherapy : CK(65) : AC(16), Deep Vein Thrombosis : CK(565) : AC(10), Radiation Induced Illness : CK(1024) : AC(249)

Pharmacological Actions : Antineoplastic Agents : CK(833) : AC(457)

Additional Keywords : Drug Side Effect Attenuation : CK(252) : AC(49)

Safety & Dosage Review: Curcumin.

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Pubmed Data : BMC Complement Altern Med. 2006;6:10. Epub 2006 Mar 17. PMID: 16545122

Article Published Date : Jan 01, 2006

Study Type : Human Study

Additional Links

Substances : Curcumin : CK(2890) : AC(1511)

Pharmacological Actions : Antineoplastic Agents : CK(833) : AC(457)

Additional Keywords : Plant Extracts : CK(3401) : AC(1158)

Solasodine glycoside cream is a safe therapy for basal cell carcinoma, with a cure rate of 66% at 8 weeks and 78% at 1 year follow-up.

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Pubmed Data : Int J Dermatol. 2008 Jan ;47(1):78-82. PMID: 18173610

Article Published Date : Jan 01, 2008

Study Type : Human Study

Additional Links

Substances : Solasodine glycoalkaloids : CK(14) : AC(4)

Diseases : Basal Cell Carcinoma : CK(26) : AC(7), Skin Cancer : CK(438) : AC(171)

Pharmacological Actions : Antineoplastic Agents : CK(833) : AC(457)

Soy isoflavones may benefit some patients with prostate cancer.

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Pubmed Data : Nutr Cancer. 2003;47(2):111-7. PMID: 15087261

Article Published Date : Jan 01, 2003

Study Type : Human Study

Additional Links

Substances : Daidzein : CK(983) : AC(28), Genistein : CK(436) : AC(174), Isoflavones : CK(627) : AC(124), Soy : CK(1698) : AC(332)

Diseases : Prostate Cancer : CK(956) : AC(288)

Pharmacological Actions : Antineoplastic Agents : CK(833) : AC(457), Apoptotic : CK(1416) : AC(1089)

The combination of curcumin and quercetin appears to reduce the number and size of ileal and rectal adenomas in patients with Familialadenomatous polyposis without appreciable toxicity.

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Pubmed Data : Clin Gastroenterol Hepatol. 2006 Aug;4(8):1035-8. Epub 2006 Jun 6. PMID: 16757216

Article Published Date : Aug 01, 2006

Study Type : Human Study

Additional Links

Substances : Curcumin : CK(2890) : AC(1511), Quercetin : CK(315) : AC(136)

Diseases : Colon Polyps : CK(42) : AC(12), Colorectal Cancer : CK(809) : AC(303), Familial Adenomatous Polyposis : CK(14) : AC(3), Gastrointestinal polyps : CK(23) : AC(4)

Pharmacological Actions : Antineoplastic Agents : CK(833) : AC(457), Antioxidants : CK(3503) : AC(1292)

The decrease in neutrophil count caused by breast carcinoma chemotherapy was ameliorated by dietary supplementation with a multivitamin or vitamin E.

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Pubmed Data : Cancer. 2004 Sep 1;101(5):1058-64. PMID: 15329916

Article Published Date : Sep 01, 2004

Study Type : Human Study

Additional Links

Substances : Folic Acid : CK(572) : AC(77), Vitamin B-12 : CK(752) : AC(94), Vitamin E : CK(1290) : AC(218)

Diseases : Breast Cancer : CK(2051) : AC(566), Chemotherapy Induced Myelotoxicity : CK(48) : AC(13), Chemotherapy-Induced Toxicity : CK(692) : AC(184), Mucositis : CK(49) : AC(10), Neutropenia: Chemotherapy Induced : CK(82) : AC(17)

Pharmacological Actions : Antineoplastic Agents : CK(833) : AC(457), Antioxidants : CK(3503) : AC(1292)

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