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Article Count - 196
Cumulative Knowledge - 767

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View the Evidence: Pharmacological Actions

Resveratrol protects against cardiac hypertrophy in an animal model.

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Pubmed Data : Cardiovasc Res. 2010 Dec 22. Epub 2010 Dec 22. PMID: 21115502

Article Published Date : Dec 22, 2010

Study Type : Animal Study

Additional Links

Substances : Resveratrol : CK(977) : AC(590)

Diseases : Cardiac Hypertrophy : CK(54) : AC(22)

Pharmacological Actions : Cardioprotective : CK(702) : AC(196)

Resveratrol protects against endothelial dysfunction.

Click here to read the entire abstract

Pubmed Data : Am J Physiol Heart Circ Physiol. 2010 Jul;299(1):H18-24. Epub 2010 Apr 23. PMID: 20418481

Article Published Date : Jul 01, 2010

Study Type : Animal Study

Additional Links

Substances : Resveratrol : CK(977) : AC(590)

Diseases : Cardiovascular Diseases : CK(5138) : AC(641), Endothelial Dysfunction : CK(897) : AC(173), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Apoptotic : CK(1489) : AC(1114), Cardioprotective : CK(702) : AC(196), Vasoprotective : CK(21) : AC(9)

Additional Keywords : Stilbenes : CK(402) : AC(242)

Resveratrol protects against lipopolysaccharide-induced oxidative stress and cardiotoxicity in the rat.

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Pubmed Data : Drug Chem Toxicol. 2011 Apr;34(2):146-50. PMID: 21314464

Article Published Date : Apr 01, 2011

Study Type : Animal Study

Additional Links

Substances : Resveratrol : CK(977) : AC(590)

Diseases : Cardiovascular Disease: Infection : CK(2) : AC(1), Cardiovascular Diseases : CK(5138) : AC(641), Lipopolysaccharide-Induced Toxicity : CK(227) : AC(128)

Pharmacological Actions : Cardioprotective : CK(702) : AC(196)

Resveratrol reduces blood cholesterol and ischemic injury in hypercholesteromic rabbits.

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Pubmed Data : Mol Cell Biochem. 2011 Feb;348(1-2):199-203. Epub 2010 Nov 4. PMID: 21052791

Article Published Date : Feb 01, 2011

Study Type : Animal Study

Additional Links

Substances : Resveratrol : CK(977) : AC(590)

Diseases : High Cholesterol : CK(1718) : AC(198), Ischemia: Myocardial : CK(35) : AC(13)

Pharmacological Actions : Anticholesteremic Agents : CK(669) : AC(142), Cardioprotective : CK(702) : AC(196)

Resveratrol reduces remodeling associated with hypertension.

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Pubmed Data : Am J Hypertens. 2010 Dec;23(12):1273-8. Epub 2010 Jul 29. PMID: 20671721

Article Published Date : Dec 01, 2010

Study Type : Animal Study

Additional Links

Substances : Resveratrol : CK(977) : AC(590)

Diseases : Aging : CK(1351) : AC(369), Hypertension : CK(2783) : AC(271)

Pharmacological Actions : Cardioprotective : CK(702) : AC(196), Hypotensive : CK(383) : AC(53)

Additional Keywords : Stilbenes : CK(402) : AC(242)

Resveratrol reduces sympathetic neural remodeling (and associated ventricular arrhythmias) in rats following myocardial infarction.

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Pubmed Data : Eur J Pharmacol. 2010 Dec 15;649(1-3):293-300. Epub 2010 Sep 24. PMID: 20869962

Article Published Date : Dec 15, 2010

Study Type : Animal Study

Additional Links

Substances : Resveratrol : CK(977) : AC(590)

Diseases : Cardiac Arrhythmias : CK(461) : AC(65), Myocardial Infarction : CK(2632) : AC(117), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Cardioprotective : CK(702) : AC(196), Neuritogenic : CK(98) : AC(48)

Additional Keywords : Stilbenes : CK(402) : AC(242)

Rhodiola rosea demonstrates significant cardioprotective and antiarrhythmic properties.

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Pubmed Data : Eksp Klin Farmakol. 2007 Sep-Oct;70(5):59-67. PMID: 18074810

Article Published Date : Sep 01, 2007

Study Type : Animal Study

Additional Links

Substances : Rhodiola (Tibetan Ginseng) : CK(119) : AC(28)

Diseases : Arrhythmias: Cardiac : CK(451) : AC(63), Cardiac Arrhythmias : CK(461) : AC(65)

Pharmacological Actions : Cardioprotective : CK(702) : AC(196)

Secoisolariciresinol diglucoside is effective in slowing the progression of atherosclerosis and partially effective in regression of hypercholesterolemic atherosclerosis.

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Pubmed Data : Curr Pharm Biotechnol. 2010 Dec;11(8):794-800. PMID: 20874684

Article Published Date : Dec 01, 2010

Study Type : Animal Study

Additional Links

Substances : Flaxseed : CK(275) : AC(57), Secoisolariciresinol diglucoside (SDG) : CK(387) : AC(5)

Diseases : Atherosclerosis : CK(523) : AC(77)

Pharmacological Actions : Cardioprotective : CK(702) : AC(196)

Additional Keywords : Disease Regression : CK(138) : AC(20)

Sesamol attenuates experimentally induced myocardial infarction.

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Pubmed Data : Cell Physiol Biochem. 2011 ;27(3-4):273-80. Epub 2011 Apr 1. PMID: 21471716

Article Published Date : Jan 01, 2011

Study Type : Animal Study

Additional Links

Substances : Sesamol : CK(79) : AC(30)

Diseases : Hypertension : CK(2783) : AC(271), Myocardial Infarction : CK(2632) : AC(117)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Cardioprotective : CK(702) : AC(196), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(153) : AC(71), Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(49) : AC(30)

Sour cherry seed extract has cardioprotective properties.

Click here to read the entire abstract

Pubmed Data : Am J Physiol Heart Circ Physiol. 2006 Sep;291(3):H1329-36. Epub 2006 Apr 14. PMID: 16617126

Article Published Date : Sep 01, 2006

Study Type : Animal Study

Additional Links

Substances : Sour Cherry : CK(4) : AC(2)

Diseases : Cardiovascular Diseases : CK(5138) : AC(641), Ischemia: Myocardial : CK(35) : AC(13)

Pharmacological Actions : Cardioprotective : CK(702) : AC(196)

Soy isoflavones in the maternal diet provides cardioprotection to the hearts of their offspring during adulthood.

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Pubmed Data : Clin Radiol. 2003 Apr;58(4):301-5. PMID: 15778278

Article Published Date : Apr 01, 2003

Study Type : Animal Study

Additional Links

Substances : Isoflavones : CK(627) : AC(124), phytoestrogens : CK(699) : AC(210), Soy : CK(1672) : AC(347)

Diseases : Heart Failure : CK(711) : AC(97)

Pharmacological Actions : Cardioprotective : CK(702) : AC(196)

Soy protein consumption may be considered as a dietary therapeutic approach for lipotoxic cardiomyopathy prevention.

Click here to read the entire abstract

Pubmed Data : J Nutr. 2009 Dec;139(12):2237-43. Epub 2009 Oct 14. PMID: 19828684

Article Published Date : Dec 01, 2009

Study Type : Animal Study

Additional Links

Substances : Soy Protein : CK(2307) : AC(56)

Diseases : Cardiac Mortality : CK(703) : AC(67), Cardiomyopathy : CK(77) : AC(15), Obesity : CK(1849) : AC(275)

Pharmacological Actions : Cardioprotective : CK(702) : AC(196)

Additional Keywords : Diseases that are Linked : CK(2122) : AC(270)

Spirulina has a protective effect against doxorubicin-induced cardiotoxicity in mice.

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2005 Dec;19(12):1030-7. PMID: 16372368

Article Published Date : Dec 01, 2005

Study Type : Animal Study

Additional Links

Substances : Spirulina : CK(75) : AC(21)

Diseases : Cardiotoxicity: Chemotherapy-Induced : CK(12) : AC(6), Chemotherapy-Induced Toxicity: Doxorubicin : CK(59) : AC(25)

Pharmacological Actions : Cardioprotective : CK(702) : AC(196)

Additional Keywords : Drug-Plant-Vitamin Synergies : CK(1011) : AC(268), Drug Side Effect Attenuation : CK(252) : AC(49)

Tanshinone IIA, a compound found within Red Sage, protects against sudden cardiac death induced by lethal arrhythmias.

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Pubmed Data : Br J Pharmacol. 2009 Nov;158(5):1227-35. Epub 2009 Sep 23. PMID: 19775284

Article Published Date : Nov 01, 2009

Study Type : Animal Study

Additional Links

Substances : Red Sage : CK(134) : AC(37)

Diseases : Cardiac Arrhythmias : CK(461) : AC(65), Cardiac Mortality : CK(703) : AC(67)

Pharmacological Actions : Cardioprotective : CK(702) : AC(196)

Taurine ameliorates cadmium-induced cardiac impairment.

Click here to read the entire abstract

Pubmed Data : Chem Biol Interact. 2008 Jul 30;174(2):88-97. Epub 2008 May 15. PMID: 18561905

Article Published Date : Jul 30, 2008

Study Type : Animal Study

Additional Links

Substances : Taurine : CK(145) : AC(33)

Diseases : Cadmium Poisoning : CK(64) : AC(30), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Cardioprotective : CK(702) : AC(196)

Terminalia arjuna protects mouse hearts against sodium flouride induced toxicity.

Click here to read the entire abstract

Pubmed Data : J Med Food. 2008 Dec;11(4):733-40. PMID: 19053867

Article Published Date : Dec 01, 2008

Study Type : Animal Study

Additional Links

Substances : Arjuna : CK(79) : AC(7), Terminalia : CK(20) : AC(13)

Diseases : Fluoride Toxicity : CK(146) : AC(40)

Pharmacological Actions : Cardioprotective : CK(702) : AC(196)

Problem Substances : Sodium Fluoride : CK(88) : AC(26)

Adverse Pharmacological Actions : Cardiotoxic : CK(638) : AC(79)

Testosterone has neuroprotective effects upon cardiac sympathetic function in rats with induced heart failure.

Click here to read the entire abstract

Pubmed Data : Eur J Pharmacol. 2009 Oct 1;619(1-3):68-74. Epub 2009 Aug 6. PMID: 19665014

Article Published Date : Oct 01, 2009

Study Type : Animal Study

Additional Links

Substances : Testosterone : CK(134) : AC(26)

Diseases : Heart Failure : CK(711) : AC(97)

Pharmacological Actions : Anti-Androgen : CK(58) : AC(15), Cardioprotective : CK(702) : AC(196), Neuroprotective Agents : CK(962) : AC(480)

Tetrahydrocurcumin and rutin have cardioprotective properties in a rat model of myocardial infarction

Click here to read the entire abstract

Pubmed Data : Pharmazie. 2009 Feb;64(2):132-6. PMID: 19320287

Article Published Date : Feb 01, 2009

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482), Rutin : CK(93) : AC(30), Tetrahydrocurcumin : CK(37) : AC(20)

Diseases : Myocardial Infarction : CK(2632) : AC(117), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Cardioprotective : CK(702) : AC(196)

The Effects of Dietary Flaxseed on Atherosclerotic Plaque Regression.

Click here to read the entire abstract

Pubmed Data : Am J Physiol Heart Circ Physiol. 2013 Apr 12. Epub 2013 Apr 12. PMID: 23585134

Article Published Date : Apr 11, 2013

Study Type : Animal Study

Additional Links

Substances : Flaxseed : CK(275) : AC(57)

Diseases : Arterial Plaque : CK(439) : AC(20), Atherosclerosis : CK(523) : AC(77), Clogged Arteries : CK(6460) : AC(285)

Pharmacological Actions : Cardioprotective : CK(702) : AC(196)

The oyster mushroom (Pleurotus ostreatus) effectively prevents the development of atherosclerosis in rabbits.

Click here to read the entire abstract

Pubmed Data : Ceska Slov Farm. 1999 Sep;48(5):226-30. PMID: 10566243

Article Published Date : Sep 01, 1999

Study Type : Animal Study

Additional Links

Substances : Oyster Mushroom : CK(33) : AC(14)

Diseases : Arteriosclerosis : CK(2154) : AC(123), Coronary Artery Disease : CK(1305) : AC(136)

Pharmacological Actions : Cardioprotective : CK(702) : AC(196)

Therapeutic potential of fucoidan in myocardial ischemia.

Click here to read the entire abstract

Pubmed Data : J Cardiovasc Pharmacol. 2011 Dec ;58(6):626-32. PMID: 22146406

Article Published Date : Nov 30, 2011

Study Type : Animal Study

Additional Links

Substances : Fucoidan : CK(152) : AC(72)

Diseases : Myocardial Infarction : CK(2632) : AC(117), Myocardial Ischemia : CK(87) : AC(37)

Pharmacological Actions : Cardioprotective : CK(702) : AC(196), Vascular Endothelial Growth Factor A Inhibitor : CK(102) : AC(58)

Tribulus terrestris attenuates the atherogenicity of a high-cholesterol diet and may repair the endothelial dysfunction resulting from hyperlipidemia.

Click here to read the entire abstract

Pubmed Data : Acta Histochem. 2009 Mar 6. PMID: 19269683

Article Published Date : Mar 06, 2009

Study Type : Animal Study

Additional Links

Substances : Tribulus : CK(50) : AC(23)

Diseases : Endothelial Dysfunction : CK(897) : AC(173), Hyperlipidemia : CK(1211) : AC(109)

Pharmacological Actions : Cardioprotective : CK(702) : AC(196)

Tribulus terrestris lowers lipidemia, relieves left ventricular remodeling, and improves cardiac function in the early stage after myocardial infarction.

Click here to read the entire abstract

Pubmed Data : Am J Chin Med. 2007;35(2):309-16. PMID: 17436370

Article Published Date : Jan 01, 2007

Study Type : Animal Study

Additional Links

Substances : Tribulus : CK(50) : AC(23)

Diseases : Myocardial Infarction : CK(2632) : AC(117)

Pharmacological Actions : Cardioprotective : CK(702) : AC(196)

Turmeric exhibits anti-atherosclerotic properties.

Click here to read the entire abstract

Pubmed Data : Biofactors. 1998;8(1-2):51-7. PMID: 9699009

Article Published Date : Jan 01, 1998

Study Type : Animal Study

Additional Links

Diseases : Alcohol Toxicity : CK(212) : AC(85), Arteriosclerosis : CK(2154) : AC(123), Atherosclerosis : CK(523) : AC(77), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Cardioprotective : CK(702) : AC(196)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Turmeric reduces oxidative stress and attenuates aortic fatty streak development in rabbits.

Click here to read the entire abstract

Pubmed Data : Arterioscler Thromb Vasc Biol. 2002 Jul 1;22(7):1225-31. PMID: 12117742

Article Published Date : Jul 01, 2002

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482), Turmeric : CK(2995) : AC(1585)

Diseases : Aortic Plaques : CK(102) : AC(9), Arteriosclerosis : CK(2154) : AC(123), Cholesterol: Oxidation : CK(457) : AC(98), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Cardioprotective : CK(702) : AC(196)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Related Blogs

Turmeric's Cardiovascular Benefits Found To Be As Powerful As Exercise

Written by Sayer Ji, Founder

Nothing can replace exercise, but turmeric extract does a pretty good job of producing some of the same cardiovascular health benefits, most notably in women undergoing age-associated adverse changes in arterial health.

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