Glutathione Upregulation

Name	AC	CK
Whey	9	48
Selenium	3	14
Sulforaphane	3	12
Coffee	2	11
MSM (Methylsulfonylmethane)	1	10
Sesamol	3	6
Astaxanthin	2	4
Ginger	2	4
Resveratrol	3	4
Arginine	2	3
EGCG (Epigallocatechin gallate)	2	3
Zinc	2	3
Catechin	1	2
Chlorella (Algae)	1	2
Chrysin	1	2
Cinnamon	1	2
Curcumin	1	2
Dandelion	2	2
Ellagic Acid	1	2
Ferulic acid	1	2
Green Tea	1	2
Holy Basil	1	2
Loquat Seeds	1	2
Moringa oleifera	1	2
Nettle	1	2
Olive leaf extract	1	2
Probiotics	1	2
Pycnogenol (Pine Bark)	1	2
Rhodiola (Tibetan Ginseng)	1	2
Rosemary	1	2
Cinnamaldehyde	1	1
Flavonoids	1	1
NAC (N-acetyl-L-cysteine)	1	1
P-Coumaric Acid	1	1
Polyphenols	1	1
Quercetin	1	1
Stilbenes	1	1
Broccoli	1	0
Nexrutine (Phellodendrom)	1	0
Sprouts	1	0

[+]

Coffee (especially dark roast) reduces body weight and restores red blood cell vitamin E and glutathione concentrations in healthy volunteers.Aug 02, 2011

Click here to read the entire abstract

Pubmed Data : Mol Nutr Food Res. 2011 Aug 2. Epub 2011 Aug 2. PMID: 21809439

Article Published Date : Aug 02, 2011

Study Type : Human Study

Additional Links

Substances : Coffee

Diseases : Overweight , Oxidative Stress, Vitamin E Deficiency

Pharmacological Actions : Antioxidants, Glutathione Upregulation

[+]

Improved glutathione status in young adult patients with cystic fibrosis supplemented with whey protein.Dec 01, 2003

Click here to read the entire abstract

Pubmed Data : J Cyst Fibros. 2003 Dec;2(4):195-8. PMID: 15463873

Article Published Date : Dec 01, 2003

Study Type : Human Study

Additional Links

Substances : Whey

Diseases : Cystic Fibrosis, Lung Diseases, Oxidative Stress

Pharmacological Actions : Antioxidants, Glutathione Upregulation

[+]

Oral sulforaphane safely and effectively induces mucosal Phase II enzyme expression in the upper airway of human subjects. Mar 01, 2009

Click here to read the entire abstract

Pubmed Data : Clin Immunol. 2009 Mar;130(3):244-51. Epub 2008 Nov 22. PMID: 19028145

Article Published Date : Mar 01, 2009

Study Type : Human Study

Additional Links

Substances : Sulforaphane

Diseases : COPD, Cystic Fibrosis, Glutathione Deficiency , Lung Diseases, Pulmonary Fibrosis, Respiratory Diseases

Pharmacological Actions : Antioxidants, Glutathione Upregulation , Phase II Detoxification Enzyme Inducer

Additional Keywords : Isothiocyanates

[+]

Oral supplementation of MSM has alleviating effects on known markers of oxidative stress following acute bouts of exercise in healthy young men.Oct 01, 2011

Click here to read the entire abstract

Pubmed Data : J Pharm Pharmacol. 2011 Oct ;63(10):1290-4. Epub 2011 Aug 1. PMID: 21899544

Article Published Date : Oct 01, 2011

Study Type : Human Study

Additional Links

Substances : MSM (Methylsulfonylmethane)

Diseases : Athletic Performance: Recovery , Oxidative Stress

Pharmacological Actions : Antioxidants, Glutathione Upregulation

[+]

Pressurized whey protein isolate can increase lymphocyte glutathione levels by 24%Sep 01, 2007

Click here to read the entire abstract

Pubmed Data : Int J Food Sci Nutr. 2007 Sep;58(6):429-36. PMID: 17710587

Article Published Date : Sep 01, 2007

Study Type : Human Study

Additional Links

Substances : Whey

Diseases : Immune Disorders: Low Immune Function

Pharmacological Actions : Glutathione Upregulation

[+]

Selenium glycinate supplementation increases blood glutathione peroxidase activities and decreases prostate-specific antigen readings in middle-aged US men.Feb 01, 2011

Click here to read the entire abstract

Pubmed Data : Nutr Res. 2011 Feb;31(2):165-8. Epub 2011 Feb 12. PMID: 21419321

Article Published Date : Feb 01, 2011

Study Type : Human Study

Additional Links

Substances : Selenium

Diseases : Glutathione Deficiency , Prostate: PSA Doubling

Pharmacological Actions : Glutathione Upregulation

[+]

Supplementation with whey proteins persistently increased plasma glutathione levels in patients with advanced HIV-infection.Feb 01, 2002

Click here to read the entire abstract

Pubmed Data : Eur J Nutr. 2002 Feb;41(1):12-8. PMID: 11990003

Article Published Date : Feb 01, 2002

Study Type : Human Study

Additional Links

Substances : Whey

Diseases : AIDS, Glutathione Deficiency , HIV Infections

Pharmacological Actions : Glutathione Upregulation

[+]

Whey protein concentrate supplementation can stimulate glutathione synthesis and, possibly, decrease the occurence of associated co-infections.Feb 01, 2006

Click here to read the entire abstract

Pubmed Data : J Trop Pediatr. 2006 Feb;52(1):34-8. Epub 2005 Jul 13. PMID: 16014759

Article Published Date : Feb 01, 2006

Study Type : Human Study

Additional Links

Substances : Whey

Diseases : Childhood Infections, Glutathione Deficiency , HIV Infections

Pharmacological Actions : Glutathione Upregulation

[+]

6-Shogaol can alleviate allergic dermatitis-like skin lesions.Oct 31, 2016

Click here to read the entire abstract

Pubmed Data : Toxicol Appl Pharmacol. 2016 Nov 1 ;310:51-59. Epub 2016 Aug 22. PMID: 27562088

Article Published Date : Oct 31, 2016

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Gingerol

Diseases : Dermatitis

Pharmacological Actions : Antioxidants, Glutathione Upregulation , Heme oxygenase-1 up-regulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Ajoene restored behavioral patterns and liver glutathione level in morphine treated C57BL6 mice.Dec 31, 2016

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Pubmed Data : Arch Pharm Res. 2017 Jan ;40(1):106-111. Epub 2016 Oct 28. PMID: 27796936

Article Published Date : Dec 31, 2016

Study Type : Animal Study

Additional Links

Substances : Garlic

Diseases : Morphine Tolerance/Dependence

Pharmacological Actions : Glutathione Upregulation , Hepatoprotective

[+]

Alpha mangostin attenuated hepatic steatosis in high fat-diet fed rats potentially through enhanced cellular antioxidant capacity.Dec 31, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutr Metab (Lond). 2016 ;13:88. Epub 2016 Dec 1. PMID: 27980597

Article Published Date : Dec 31, 2015

Study Type : Animal Study

Additional Links

Substances : Mangosteen

Diseases : High Fat Diet, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Catalase Up-Regulation, Glutathione Upregulation , Hepatoprotective, Superoxide Dismutase Up-regulation

[+]

Astaxanthin improves diabetic complications associated wtih dental pulp tissue. Nov 01, 2010

Click here to read the entire abstract

Pubmed Data : Int Endod J. 2010 Nov;43(11):959-67. PMID: 20546046

Article Published Date : Nov 01, 2010

Study Type : Animal Study

Additional Links

Substances : Astaxanthin

Diseases : Diabetes: Dental Problems, Diabetic Complications

Pharmacological Actions : Antioxidants, Glutathione Upregulation

[+]

Astaxanthin restores the enzymatic antioxidant profile in salivary gland of alloxan-induced diabetic rats.Jul 01, 2010

Click here to read the entire abstract

Pubmed Data : Arch Oral Biol. 2010 Jul;55(7):479-85. PMID: 20510163

Article Published Date : Jul 01, 2010

Study Type : Animal Study

Additional Links

Substances : Astaxanthin

Diseases : Diabetes: Oxidative Stress, Oxidative Stress

Pharmacological Actions : Antioxidants, Glutathione Upregulation

[+]

Chlorella vulgaris extract ameliorates carbon tetrachloride-induced acute hepatic injury in mice.Jul 07, 2011

Click here to read the entire abstract

Pubmed Data : Exp Toxicol Pathol. 2011 Jul 7. Epub 2011 Jul 7. PMID: 21741806

Article Published Date : Jul 07, 2011

Study Type : Animal Study

Additional Links

Substances : Chlorella (Algae)

Diseases : Chemically-Induced Liver Damage, Liver Damage

Pharmacological Actions : Glutathione Upregulation , Hepatoprotective

[+]

Chrysin protects against free radical-mediated oxidative stress in rats with ethanol-induced liver injury. Jun 01, 2009

Click here to read the entire abstract

Pubmed Data : J Pharm Pharmacol. 2009 Jun;61(6):809-17. PMID: 19505373

Article Published Date : Jun 01, 2009

Study Type : Animal Study

Additional Links

Substances : Chrysin

Diseases : Alcohol Toxicity , Alcoholic Liver Disease, Liver Cirrhosis: Alcoholic

Pharmacological Actions : Glutathione Upregulation , Hepatoprotective

[+]

Cinnamon and rhodiola have significant blood sugar lowering and antioxidant activity.Jan 01, 2006

Click here to read the entire abstract

Pubmed Data : Biofactors. 2006;26(3):209-19. PMID: 16971752

Article Published Date : Jan 01, 2006

Study Type : Animal Study

Additional Links

Substances : Cinnamon, Rhodiola (Tibetan Ginseng)

Diseases : Diabetes Mellitus: Type 1, Diabetes Mellitus: Type 2

Pharmacological Actions : Antioxidants, Glutathione Upregulation

[+]

Coenzyme Q10 has a coloprotective effect against experimentally induced ulcerative colitis.Jan 02, 2017

Click here to read the entire abstract

Pubmed Data : Inflammopharmacology. 2017 Jan 3. Epub 2017 Jan 3. PMID: 28050757

Article Published Date : Jan 02, 2017

Study Type : Animal Study

Additional Links

Substances : Coenzyme Q10

Diseases : Ulcerative Colitis

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Catalase Up-Regulation, Glutathione Upregulation , Heme oxygenase-1 up-regulation, Malondialdehyde Down-regulation, Nrf2 activation, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Dose Response

[+]

Curcumin treatment alleviates the effects of glutathione depletion in vitro and in vivo, indicating its value for Parkinson disease. Mar 01, 2008

Click here to read the entire abstract

Pubmed Data : Free Radic Biol Med. 2008 Mar 1;44(5):907-17. Epub 2007 Dec 4. PMID: 18166164

Article Published Date : Mar 01, 2008

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Oxidative Stress, Parkinson's Disease

Pharmacological Actions : Antineoplastic Agents, Glutathione Upregulation , Neuroprotective Agents

[+]

EGCG protects against muscle wasting disease, in a mouse model. Apr 14, 2010

Click here to read the entire abstract

Pubmed Data : J Agric Food Chem. 2010 Apr 14;58(7):4523-8. PMID: 19322813

Article Published Date : Apr 14, 2010

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Muscle Atrophy , Muscular Dystrophies

Pharmacological Actions : Glutathione Upregulation

[+]

Embelia ribes extract reduces high fat diet and low dose streptozotocin-induced diabetic nephrotoxicity in rats.Dec 31, 2012

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : EXCLI J. 2013 ;12:858-71. Epub 2013 Sep 24. PMID: 26622220

Article Published Date : Dec 31, 2012

Study Type : Animal Study

Additional Links

Substances : False Black Pepper

Diseases : Diabetes Mellitus: Type 2, Diabetic Nephropathy, Lipid Peroxidation

Pharmacological Actions : Antihypertensive Agents, Antioxidants, Catalase Up-Regulation, Glutathione Upregulation , Insulin Sensitizers, Renoprotective, Superoxide Dismutase Up-regulation

Additional Keywords : Plant Extracts

[+]

Fresh nettle leaves are a natural protective herb that may play a beneficial role in the prevention of Hg intoxication.Nov 30, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Vet World. 2015 Dec ;8(12):1458-65. PMID: 27047060

Article Published Date : Nov 30, 2015

Study Type : Animal Study

Additional Links

Substances : Nettle

Diseases : Mercury Poisoning

Pharmacological Actions : Glutathione Upregulation

Additional Keywords : Herbal Teas, Methylmercury

Problem Substances : Mercury

[+]

Ginger protects against dichlorvos and lindane induced oxidative stress in rat brain. Jan 01, 2012

Click here to read the entire abstract

Pubmed Data : Pharmacognosy Res. 2012 Jan ;4(1):27-32. PMID: 22224058

Article Published Date : Jan 01, 2012

Study Type : Animal Study

Additional Links

Substances : Ginger

Diseases : Brain Damage

Pharmacological Actions : Glutathione Upregulation , Neuroprotective Agents, Superoxide Dismutase Up-regulation

Problem Substances : Dichlorvos, Lindane

[+]

Ginger protects against liver fibrosis.Jan 01, 2011

Click here to read the entire abstract

Pubmed Data : Nutr Metab (Lond). 2011 ;8:40. Epub 2011 Jun 20. PMID: 21689445

Article Published Date : Jan 01, 2011

Study Type : Animal Study

Additional Links

Substances : Ginger

Diseases : ALT: Elevated, AST: Elevated, Liver Fibrosis

Pharmacological Actions : Glutathione Upregulation , Malonaldehyde (MDA) Down-Regulation, Renoprotective, Superoxide Dismutase Up-regulation

[+]

Green tea catechin prevents the decline of glutathione peroxidase activity and protein oxidative damage in aging mouse brain.Aug 01, 2007

Click here to read the entire abstract

Pubmed Data : Biogerontology. 2007 Aug;8(4):423-30. Epub 2007 Feb 20. PMID: 17310319

Article Published Date : Aug 01, 2007

Study Type : Animal Study

Additional Links

Substances : Catechin , Green Tea

Diseases : Aging, Aging: Brain , Oxidative Stress

Pharmacological Actions : Antioxidants, Glutathione Upregulation , Neuroprotective Agents

[+]

Holy basil (O. sanctum) protects against radiation injury through modulating glutathione and antioxidant enzymes. Mar 01, 1999

Click here to read the entire abstract

Pubmed Data : Indian J Exp Biol. 1999 Mar;37(3):262-8. PMID: 10641157

Article Published Date : Mar 01, 1999

Study Type : Animal Study

Additional Links

Substances : Holy Basil

Diseases : Radiation Induced Illness

Pharmacological Actions : Glutathione Upregulation , Radioprotective

[+]

L-arginine protects against pulmonary oxidative stress and antioxidant defenses during exhaustive exercise in rats.Aug 01, 2005

Click here to read the entire abstract

Pubmed Data : Acta Pharmacol Sin. 2005 Aug;26(8):992-9. PMID: 16038634

Article Published Date : Aug 01, 2005

Study Type : Animal Study

Additional Links

Substances : Arginine

Diseases : Exercise-Induced Tissue Damage, Lipid Peroxidation, Lung Damage, Oxidative Stress

Pharmacological Actions : Antioxidants, Glutathione Upregulation , Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation

[+]

Loquat seed inhibits oxidative stress associated wtih adriamycin-induced nephropathy. Dec 01, 2004

Click here to read the entire abstract

Pubmed Data : Biol Pharm Bull. 2004 Dec;27(12):1961-4. PMID: 15577213

Article Published Date : Dec 01, 2004

Study Type : Animal Study

Additional Links

Substances : Loquat Seeds

Diseases : Chemotherapy-Induced Toxicity: Adriamycin, Lipid Peroxidation, Nephropathy, Oxidative Stress

Pharmacological Actions : Glutathione Upregulation , Renoprotective

Additional Keywords : Drug: Doxorubicin, Plant Extracts

[+]

Lychee pulp phenolics protect the liver against restraint stress-induced damage by scavenging free radicals and modulating mitochondrial dysfunction.Dec 31, 2015

Click here to read the entire abstract

Pubmed Data : Food Funct. 2016 Jan ;7(1):508-15. PMID: 26569420

Article Published Date : Dec 31, 2015

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Litchi

Diseases : Liver Damage, Mitochondrial Dysfunction , Oxidative Stress

Pharmacological Actions : Antioxidants, Catalase Up-Regulation, Glutathione Upregulation , Hepatoprotective, Superoxide Dismutase Up-regulation

Additional Keywords : Antioxidants, Catalase Up-Regulation, Litchi, liver damage, Mitochondrial Dysfunction, oxidative stress, Plant Extracts

[+]

Moringa oleifera prevents acetaminophen induced liver injury through restoration of glutathione level. Aug 01, 2008

Click here to read the entire abstract

Pubmed Data : Food Chem Toxicol. 2008 Aug;46(8):2611-5. Epub 2008 Apr 25. PMID: 18514995

Article Published Date : Aug 01, 2008

Study Type : Animal Study

Additional Links

Substances : Moringa oleifera

Diseases : Acetaminophen (Tylenol) Toxicity

Pharmacological Actions : Glutathione Upregulation

[+]

Olive leaf extract ameliorates gentamicin nephrotoxicity via antioxidant activity, increase of renal glutathione content, and increase of renal antioxidant enzymes activity, except for glutathione peroxidase.Jan 01, 2012

Click here to read the entire abstract

Pubmed Data : Iran J Kidney Dis. 2012 Jan ;6(1):25-32. PMID: 22218116

Article Published Date : Jan 01, 2012

Study Type : Animal Study

Additional Links

Substances : Olive leaf extract

Diseases : Chemotherapy-Induced Toxicity: Gentamicin

Pharmacological Actions : Antioxidants, Glutathione Upregulation , Renoprotective

Problem Substances : Gentamicin

Adverse Pharmacological Actions : Nephrotoxic, Oxidant

[+]

Oral administration of Ellagic acid and Ferulic acid may ameliorate gamma radiation and aluminium chloride induced oxidative damage.Jul 15, 2016

Click here to read the entire abstract

Pubmed Data : Life Sci. 2016 Jul 16. Epub 2016 Jul 16. PMID: 27436544

Article Published Date : Jul 15, 2016

Study Type : Animal Study

Additional Links

Substances : Ellagic Acid, Ferulic acid

Diseases : Chemotherapy and Radiation Toxicity

Pharmacological Actions : Antioxidants, Catalase Up-Regulation, Glutathione Upregulation , Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation

Problem Substances : Aluminum Chloride

[+]

Oral supplementation with whey proteins increases plasma glutathione levels of HIV-infected patients.Feb 01, 2001

Click here to read the entire abstract

Pubmed Data : Eur J Clin Invest. 2001 Feb;31(2):171-8. PMID: 11168457

Article Published Date : Feb 01, 2001

Study Type : Animal Study

Additional Links

Substances : Whey

Diseases : AIDS, Glutathione Deficiency , HIV Infections

Pharmacological Actions : Antioxidants, Glutathione Upregulation

[+]

Parsley is effective in reducing stress-induced gastric injury by supporting the cellular antioxidant defence system.Dec 31, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Balkan Med J. 2017 Jan ;34(1):53-59. Epub 2017 Jan 5. PMID: 28251024

Article Published Date : Dec 31, 2016

Study Type : Animal Study

Additional Links

Substances : Parsley

Diseases : Oxidative Stress

Pharmacological Actions : Antioxidants, Catalase Up-Regulation, Gastroprotective, Glutathione Upregulation , Superoxide Dismutase Up-regulation

[+]

Photobiomodulation therapy reduces apoptotic factors and increases glutathione levels in a neuropathic pain model.Nov 30, 2016

Click here to read the entire abstract

Pubmed Data : Lasers Med Sci. 2016 Dec ;31(9):1863-1869. Epub 2016 Sep 17. PMID: 27640000

Article Published Date : Nov 30, 2016

Study Type : Animal Study

Additional Links

Diseases : Neuropathic Pain

Therapeutic Actions : Laser Treatment: Low-Level

Pharmacological Actions : Anti-Apoptotic, Glutathione Upregulation

[+]

Pinus massoniana bark extract treatment prevents hydrogen peroxide and carbon tetrachloride induced liver damage.Dec 31, 2009

Click here to read the entire abstract

Pubmed Data : Am J Chin Med. 2010 ;38(5):909-19. PMID: 20821822

Article Published Date : Dec 31, 2009

Study Type : Animal Study

Additional Links

Substances : Pine Bark Extract

Diseases : Chemically-Induced Liver Damage, Hydrogen Peroxide Induced Toxicity, Oxidative Stress

Pharmacological Actions : Antioxidants, Glutathione Upregulation , Hepatoprotective, Malondialdehyde Down-regulation

Additional Keywords : Phytotherapy, Plant Extracts

[+]

Polysaccharides from Ganoderma lucidum played a positive protective role in the pulmonary fibrosis.Oct 31, 2016

Click here to read the entire abstract

Pubmed Data : Int J Biol Macromol. 2016 Nov ;92:278-281. Epub 2016 Aug 2. PMID: 27381587

Article Published Date : Oct 31, 2016

Study Type : Animal Study

Additional Links

Substances : Reishi Mushroom

Diseases : Pulmonary Fibrosis: Bleomycin-Induced

Pharmacological Actions : Antioxidants, Catalase Up-Regulation, Glutathione Upregulation , Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation

Additional Keywords : Polysaccharides

[+]

Probiotics enhance glutathione biosynthesis and reduce oxidative stress in experimental acute pancreatitis. Nov 01, 2008

Click here to read the entire abstract

Pubmed Data : Am J Physiol Gastrointest Liver Physiol. 2008 Nov;295(5):G1111-21. Epub 2008 Oct 2. PMID: 18832452

Article Published Date : Nov 01, 2008

Study Type : Animal Study

Additional Links

Substances : Probiotics

Diseases : Pancreatitis

Pharmacological Actions : Glutathione Upregulation

[+]

Pycnogenol treatment attenuated α-chlorohydrin-induced spermatotoxicity through antioxidant and antiapoptotic effects.Feb 28, 2014

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2014 Mar ;28(3):451-7. Epub 2013 Jun 21. PMID: 23788506

Article Published Date : Feb 28, 2014

Study Type : Animal Study

Additional Links

Substances : Pycnogenol (Pine Bark)

Diseases : Lipid Peroxidation, Sperm Quality: Low

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Glutathione Upregulation , Malondialdehyde Down-regulation

Additional Keywords : Plant Extracts

[+]

Rosemary attenuates radiation-induced toxicity.Oct 01, 2007

Click here to read the entire abstract

Pubmed Data : Phytomedicine. 2007 Oct;14(10):701-5. Epub 2007 Apr 12. PMID: 17433646

Article Published Date : Oct 01, 2007

Study Type : Animal Study

Additional Links

Substances : Rosemary

Diseases : Lipid Peroxidation, Radiation Induced Illness

Pharmacological Actions : Glutathione Upregulation , Radioprotective

Additional Keywords : Plant Extracts

[+]

Selenium inhibits pancreatic cancer cell growth in hamsters. Jul 15, 1990

Click here to read the entire abstract

Pubmed Data : Int J Cancer. 1990 Jul 15;46(1):95-100. PMID: 2365502

Article Published Date : Jul 15, 1990

Study Type : Animal Study

Additional Links

Substances : Selenium

Diseases : Prostate Cancer

Pharmacological Actions : Glutathione Upregulation

[+]

Sesamol exhibits anti-depressant properties.Apr 01, 2011

Click here to read the entire abstract

Pubmed Data : Psychopharmacology (Berl). 2011 Apr ;214(4):819-28. Epub 2010 Nov 20. PMID: 21103863

Article Published Date : Apr 01, 2011

Study Type : Animal Study

Additional Links

Substances : Sesamol

Diseases : Depression, Lipid Peroxidation

Pharmacological Actions : Antidepressive Agents, Catalase Up-Regulation, Glutathione Upregulation , Superoxide Dismutase Up-regulation

[+]

Sesamol protects against chemically-induced oxidative renal injury in rats. Apr 01, 2009

Click here to read the entire abstract

Pubmed Data : Basic Clin Pharmacol Toxicol. 2009 Apr ;104(4):316-21. Epub 2009 Feb 27. PMID: 19281599

Article Published Date : Apr 01, 2009

Study Type : Animal Study

Additional Links

Substances : Sesamol

Diseases : Kidney Damage, Lipid Peroxidation, Oxidative Stress

Pharmacological Actions : Antioxidants, Glutathione Upregulation , Renoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Sesamol protects against myocardial infarction. Jan 01, 2010

Click here to read the entire abstract

Pubmed Data : Redox Rep. 2010 ;15(1):36-42. PMID: 20196927

Article Published Date : Jan 01, 2010

Study Type : Animal Study

Additional Links

Substances : Sesamol

Diseases : Lipid Peroxidation, Myocardial Infarction: Prevention

Pharmacological Actions : Antioxidants, Glutathione Upregulation , Mitochondrial Superoxide Dismutase Upregulation

[+]

Sesamol reduces total oxidant status, malondialdehyde levels and inhibits cataract formation.Nov 30, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Turk J Ophthalmol. 2017 Dec ;47(6):309-314. Epub 2017 Dec 27. PMID: 29326846

Article Published Date : Nov 30, 2017

Study Type : Animal Study

Additional Links

Substances : Sesamol

Diseases : Cataract

Pharmacological Actions : Antioxidants, Glutathione Upregulation , Malondialdehyde Down-regulation

[+]

These results validate the use of saffron as a treatment against diabetes mellitus and its vascular complications.Mar 31, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Indian Heart J. 2017 Mar - Apr;69(2):151-159. Epub 2016 Sep 25. PMID: 28460761

Article Published Date : Mar 31, 2017

Study Type : Animal Study

Additional Links

Substances : Saffron

Diseases : Diabetic Complications

Pharmacological Actions : Anticholesteremic Agents, Antioxidants, Catalase Up-Regulation, Glutathione Upregulation , Hypoglycemic Agents, Hypolipidemic, Immunomodulatory, Malondialdehyde Down-regulation, Nitric Oxide Inhibitor, Superoxide Dismutase Up-regulation

Additional Keywords : Plant Extracts

[+]

Trans-resveratrol at low doses may have a therapeutic role in preventing liver damage during surgery or transplantation. Oct 01, 2008

Click here to read the entire abstract

Pubmed Data : J Ocul Pharmacol Ther. 2008 Oct;24(5):439-44. PMID: 18383089

Article Published Date : Oct 01, 2008

Study Type : Animal Study

Additional Links

Substances : Resveratrol

Diseases : Organ Transplantation: Liver, Surgery: Liver, Surgery: Recovery

Pharmacological Actions : Glutathione Upregulation

[+]

Turmeric extract and curcumin can protect the liver from acute carbon tetrachloride induced injury.Jan 31, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMC Res Notes. 2017 Feb 1 ;10(1):77. Epub 2017 Feb 1. PMID: 28143589

Article Published Date : Jan 31, 2017

Study Type : Animal Study

Additional Links

Substances : Curcumin, Turmeric

Diseases : Chemically-Induced Liver Damage, Lipid Peroxidation, Oxidative Stress

Pharmacological Actions : Glutathione Upregulation , Hepatoprotective, Superoxide Dismutase Up-regulation

Additional Keywords : Phytotherapy, Plant Extracts

Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

[+]

Virgin coconut oil has the potential to be used as a memory enhancer.Nov 30, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Pharm Biol. 2017 Dec ;55(1):825-832. PMID: 28118770

Article Published Date : Nov 30, 2017

Study Type : Animal Study

Additional Links

Substances : Virgin Coconut Oil

Diseases : Memory Disorders

Pharmacological Actions : Acetylcholinesterase Down-Regulation, Antioxidants, Catalase Up-Regulation, Glutathione Upregulation , Malondialdehyde Down-regulation, Neuroprotective Agents, Nitric Oxide Inhibitor, Superoxide Dismutase Up-regulation

[+]

Whey protein hydrolysates increase liver glutathione synthesis in mice.Jan 01, 2005

Click here to read the entire abstract

Pubmed Data : J Med Food. 2005;8(3):337-42. PMID: 16176144

Article Published Date : Jan 01, 2005

Study Type : Animal Study

Additional Links

Substances : Whey

Diseases : Glutathione Deficiency

Pharmacological Actions : Glutathione Upregulation

[+]

Whey supplementation may improve wound healing.Mar 01, 2008

Click here to read the entire abstract

Pubmed Data : Int J Vitam Nutr Res. 2008 Mar;78(2):70-3. PMID: 18791975

Article Published Date : Mar 01, 2008

Study Type : Animal Study

Additional Links

Substances : Whey

Diseases : Wound Healing

Pharmacological Actions : Antioxidants, Glutathione Upregulation , Interleukin-1 beta downregulation

[+]

Zinc and selenium protects against benzene toxicity in rats.Apr 21, 2011

Click here to read the entire abstract

Pubmed Data : Toxicol Ind Health. 2011 Apr 21. Epub 2011 Apr 21. PMID: 21511895

Article Published Date : Apr 21, 2011

Study Type : Animal Study

Additional Links

Substances : Selenium, Zinc

Diseases : Benzene Toxicity

Pharmacological Actions : Catalase Up-Regulation, Glutathione Upregulation , GSH-Px Up-Regulation, Malonaldehyde (MDA) Down-Regulation, Superoxide Dismutase Up-regulation

[+]

Cinnamaldehyde enhances detoxification by increasing phase 2 enzyme expression. May 11, 2011

Click here to read the entire abstract

Pubmed Data : J Agric Food Chem. 2011 May 11;59(9):5164-71. Epub 2011 Apr 15. PMID: 21469739

Article Published Date : May 11, 2011

Study Type : In Vitro Study

Additional Links

Substances : Cinnamaldehyde

Diseases : Intoxication

Pharmacological Actions : Glutathione Upregulation , Phase II Detoxification Enzyme Inducer

[+]

Coffee may exert its chemopreventive properties through metabolism and detoxification of xenobiotics.Jan 01, 2005

Click here to read the entire abstract

Pubmed Data : Methods Enzymol. 2005;401:307-41. PMID: 16399395

Article Published Date : Jan 01, 2005

Study Type : Review

Additional Links

Substances : Coffee, Flavonoids, Polyphenols

Diseases : Cancers: All

Pharmacological Actions : Chemopreventive, Glutathione Upregulation

Additional Keywords : Plant Extracts, Xenobiotic Metabolism

[+]

Dandelion extract inhibits lipopolysaccharide-induced oxidative stress and nitric oxide production associated with inflammation. Jan 27, 2011

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 2011 Jan 27;133(2):834-42. Epub 2010 Nov 11. PMID: 21075189

Article Published Date : Jan 27, 2011

Study Type : In Vitro Study

Additional Links

Substances : Dandelion

Diseases : Glutathione Deficiency , Lipopolysaccharide-Induced Toxicity, Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Glutathione Upregulation , NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Superoxide Dismutase Up-regulation

[+]

Dandelion extracts especially leaf and flower extracts are potent protective agents against UVB damage.Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oxid Med Cell Longev. 2015 ;2015:619560. Epub 2015 Oct 20. PMID: 26576225

Article Published Date : Dec 31, 2014

Study Type : In Vitro Study

Additional Links

Substances : Dandelion

Diseases : Ultraviolet Radiation Induced Damage

Pharmacological Actions : Antioxidants, Glutathione Upregulation

Additional Keywords : Plant Extracts

[+]

EGCG has antifibrogenic activity relevant to the prevention and treatment of liver fibrosis. Jul 01, 2006

Click here to read the entire abstract

Pubmed Data : Lab Invest. 2006 Jul;86(7):697-709. Epub 2006 May 8. PMID: 16682975

Article Published Date : Jul 01, 2006

Study Type : In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Fibrosis: Liver, Liver Fibrosis

Pharmacological Actions : Glutathione Upregulation

[+]

l-Arginine supplementation induces glutathione synthesis in interscapular brown adipose tissue.Dec 10, 2009

Click here to read the entire abstract

Pubmed Data : Chem Biol Interact. 2009 Dec 10;182(2-3):204-12. Epub 2009 Jul 22. PMID: 19631198

Article Published Date : Dec 10, 2009

Study Type : In Vitro Study

Additional Links

Substances : Arginine

Diseases : Glutathione Deficiency

Pharmacological Actions : Glutathione Upregulation

[+]

Melatonin may be an effectively protective agent against H2O2-induced oxidative stress and apoptosis in bone marrow mesenchymal stem cells.Dec 22, 2016

Click here to read the entire abstract

Pubmed Data : Can J Physiol Pharmacol. 2016 Dec 23. Epub 2016 Dec 23. PMID: 28177678

Article Published Date : Dec 22, 2016

Study Type : In Vitro Study

Additional Links

Substances : Melatonin

Diseases : Hydrogen Peroxide Induced Toxicity

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Catalase Up-Regulation, Glutathione Upregulation , Interleukin-6 Downregulation, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Mesenchymal Stem Cells

[+]

N-acetyl cysteine has antiproliferative on pancreatic cancer cells. Dec 01, 2000

Click here to read the entire abstract

Pubmed Data : Hum Cell. 2000 Dec;13(4):213-20. PMID: 11329937

Article Published Date : Dec 01, 2000

Study Type : In Vitro Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Pancreatic Cancer

Pharmacological Actions : Glutathione Upregulation

[+]

Resveratrol reduces endothelial oxidative stress.May 01, 2008

Click here to read the entire abstract

Pubmed Data : Phytochemistry. 2008 May;69(8):1732-8. Epub 2008 Apr 15. PMID: 20083859

Article Published Date : May 01, 2008

Study Type : In Vitro Study

Additional Links

Substances : Resveratrol, Stilbenes

Diseases : Endothelial Dysfunction, Oxidative Stress

Pharmacological Actions : Antioxidants, Glutathione Peroxidase 1 (GPx1) Up-Regulation, Glutathione Upregulation , NADPH Oxidase Inhibitors, Superoxide Dismutase Up-regulation

[+]

Silymarin can effectively alleviate acrylamide induced neurotoxicity in PC12 cells.Mar 31, 2017

Click here to read the entire abstract

Pubmed Data : Food Chem Toxicol. 2017 Apr ;102:93-101. Epub 2017 Jan 27. PMID: 28137608

Article Published Date : Mar 31, 2017

Study Type : In Vitro Study

Additional Links

Substances : Silymarin

Diseases : Acrylamide-induced toxicity

Pharmacological Actions : Antioxidants, Glutathione Upregulation , Malondialdehyde Down-regulation, Neuroprotective Agents, Nrf2 activation

Problem Substances : Acrylamide

[+]

Sulforaphane treatment may present a strategy for enhancing the cellular defense mechanisms in skin.Feb 01, 2010

Click here to read the entire abstract

Pubmed Data : Exp Dermatol. 2010 Feb;19(2):137-44. Epub 2009 Jun 23. PMID: 19558496

Article Published Date : Feb 01, 2010

Study Type : In Vitro Study

Additional Links

Substances : Sulforaphane

Diseases : Aging Skin, Glutathione Deficiency , Skin Diseases

Pharmacological Actions : Anticarcinogenic Agents, Glutathione Upregulation , NF-kappaB Inhibitor

[+]

This review summarises the many health benefits of Sulforaphane as a antioxidant dietary supplement.May 04, 2015

Click here to read the entire abstract

Pubmed Data : Recent Pat Endocr Metab Immune Drug Discov. 2015 May 5. Epub 2015 May 5. PMID: 25944116

Article Published Date : May 04, 2015

Study Type : Review

Additional Links

Substances : Sulforaphane

Diseases : Cancers: All, Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Anticarcinogenic Agents, Antioxidants, Glutathione Upregulation , Nrf2 activation

Additional Keywords : Detoxification, Dose Response, Epigenetic Modification

[+]

Various polyphenols exhibit potential anti-obesity activity. Jan 26, 2011

Click here to read the entire abstract

Pubmed Data : J Agric Food Chem. 2011 Jan 26;59(2):546-51. Epub 2010 Dec 27. PMID: 21186817

Article Published Date : Jan 26, 2011

Study Type : In Vitro Study

Additional Links

Substances : P-Coumaric Acid, Quercetin, Resveratrol

Diseases : Obesity

Pharmacological Actions : Glutathione Upregulation , Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Whey protein concentrate may positively modulate glutathione in cancer treatment.Nov 01, 2000

Click here to read the entire abstract

Pubmed Data : Anticancer Res. 2000 Nov-Dec;20(6C):4785-92. PMID: 11205219

Article Published Date : Nov 01, 2000

Study Type : Review

Additional Links

Substances : Whey

Diseases : Cancers: All, Male Urogenital Diseases, Urinary Tract Cancer, Urogenital Cancers

Pharmacological Actions : Antineoplastic Agents, Glutathione Upregulation

[+]

Whey protein may exert its anti-carcinogenic effect by enhancing glutathione concentrations.May 01, 1991

Click here to read the entire abstract

Pubmed Data : Cancer Lett. 1991 May 1;57(2):91-4. PMID: 2025891

Article Published Date : May 01, 1991

Study Type : Commentary

Additional Links

Substances : Whey

Diseases : Glutathione Deficiency

Pharmacological Actions : Anticarcinogenic Agents, Glutathione Upregulation

[+]

Zinc may have radioprotective properties against radioiodine-131 toxicity in red blood cells.Oct 01, 2005

Click here to read the entire abstract

Pubmed Data : Indian J Med Res. 2005 Oct;122(4):338-42. PMID: 16394327

Article Published Date : Oct 01, 2005

Study Type : In Vitro Study

Additional Links

Substances : Zinc

Diseases : Radiation-Induced Illness: Radioiodine (Iodine-131)

Pharmacological Actions : Glutathione Upregulation , Mitochondrial Superoxide Dismutase Upregulation, Radioprotective

[+]

Broccoli sprouts correct phase 2 enzyme expression in human prostate cancer cells.Sep 01, 2001

Click here to read the entire abstract

Pubmed Data : Cancer Epidemiol Biomarkers Prev. 2001 Sep;10(9):949-54. PMID: 11535546

Article Published Date : Sep 01, 2001

Additional Links

Substances : Broccoli, Sprouts

Diseases : Prostate Cancer

Pharmacological Actions : Glutathione Upregulation

[+]

Phellodendron amurense has the highest glutathione S-transferase activiting activity of 265 kinds of medicinal plants tested.Sep 01, 2006

Click here to read the entire abstract

Pubmed Data : Peptides. 2006 Sep;27(9):2069-74. Epub 2006 Apr 19. PMID: 16624447

Article Published Date : Sep 01, 2006

Additional Links

Substances : Nexrutine (Phellodendrom)

Pharmacological Actions : Glutathione Upregulation

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Coffee (especially dark roast) reduces body weight and restores red blood cell vitamin E and glutathione concentrations in healthy volunteers.Aug 02, 2011

Improved glutathione status in young adult patients with cystic fibrosis supplemented with whey protein.Dec 01, 2003

Oral sulforaphane safely and effectively induces mucosal Phase II enzyme expression in the upper airway of human subjects. Mar 01, 2009

Oral supplementation of MSM has alleviating effects on known markers of oxidative stress following acute bouts of exercise in healthy young men.Oct 01, 2011

Pressurized whey protein isolate can increase lymphocyte glutathione levels by 24%Sep 01, 2007

Selenium glycinate supplementation increases blood glutathione peroxidase activities and decreases prostate-specific antigen readings in middle-aged US men.Feb 01, 2011

Supplementation with whey proteins persistently increased plasma glutathione levels in patients with advanced HIV-infection.Feb 01, 2002

Whey protein concentrate supplementation can stimulate glutathione synthesis and, possibly, decrease the occurence of associated co-infections.Feb 01, 2006

6-Shogaol can alleviate allergic dermatitis-like skin lesions.Oct 31, 2016

Ajoene restored behavioral patterns and liver glutathione level in morphine treated C57BL6 mice.Dec 31, 2016

Alpha mangostin attenuated hepatic steatosis in high fat-diet fed rats potentially through enhanced cellular antioxidant capacity.Dec 31, 2015

Astaxanthin improves diabetic complications associated wtih dental pulp tissue. Nov 01, 2010

Astaxanthin restores the enzymatic antioxidant profile in salivary gland of alloxan-induced diabetic rats.Jul 01, 2010

Chlorella vulgaris extract ameliorates carbon tetrachloride-induced acute hepatic injury in mice.Jul 07, 2011

Chrysin protects against free radical-mediated oxidative stress in rats with ethanol-induced liver injury. Jun 01, 2009

Cinnamon and rhodiola have significant blood sugar lowering and antioxidant activity.Jan 01, 2006

Coenzyme Q10 has a coloprotective effect against experimentally induced ulcerative colitis.Jan 02, 2017

Curcumin treatment alleviates the effects of glutathione depletion in vitro and in vivo, indicating its value for Parkinson disease. Mar 01, 2008

EGCG protects against muscle wasting disease, in a mouse model. Apr 14, 2010

Embelia ribes extract reduces high fat diet and low dose streptozotocin-induced diabetic nephrotoxicity in rats.Dec 31, 2012

Fresh nettle leaves are a natural protective herb that may play a beneficial role in the prevention of Hg intoxication.Nov 30, 2015

Ginger protects against dichlorvos and lindane induced oxidative stress in rat brain. Jan 01, 2012

Ginger protects against liver fibrosis.Jan 01, 2011

Green tea catechin prevents the decline of glutathione peroxidase activity and protein oxidative damage in aging mouse brain.Aug 01, 2007

Holy basil (O. sanctum) protects against radiation injury through modulating glutathione and antioxidant enzymes. Mar 01, 1999

L-arginine protects against pulmonary oxidative stress and antioxidant defenses during exhaustive exercise in rats.Aug 01, 2005

Loquat seed inhibits oxidative stress associated wtih adriamycin-induced nephropathy. Dec 01, 2004

Lychee pulp phenolics protect the liver against restraint stress-induced damage by scavenging free radicals and modulating mitochondrial dysfunction.Dec 31, 2015

Moringa oleifera prevents acetaminophen induced liver injury through restoration of glutathione level. Aug 01, 2008

Olive leaf extract ameliorates gentamicin nephrotoxicity via antioxidant activity, increase of renal glutathione content, and increase of renal antioxidant enzymes activity, except for glutathione peroxidase.Jan 01, 2012

Oral administration of Ellagic acid and Ferulic acid may ameliorate gamma radiation and aluminium chloride induced oxidative damage.Jul 15, 2016

Oral supplementation with whey proteins increases plasma glutathione levels of HIV-infected patients.Feb 01, 2001

Parsley is effective in reducing stress-induced gastric injury by supporting the cellular antioxidant defence system.Dec 31, 2016

Photobiomodulation therapy reduces apoptotic factors and increases glutathione levels in a neuropathic pain model.Nov 30, 2016

Pinus massoniana bark extract treatment prevents hydrogen peroxide and carbon tetrachloride induced liver damage.Dec 31, 2009

Polysaccharides from Ganoderma lucidum played a positive protective role in the pulmonary fibrosis.Oct 31, 2016

Probiotics enhance glutathione biosynthesis and reduce oxidative stress in experimental acute pancreatitis. Nov 01, 2008

Pycnogenol treatment attenuated α-chlorohydrin-induced spermatotoxicity through antioxidant and antiapoptotic effects.Feb 28, 2014

Rosemary attenuates radiation-induced toxicity.Oct 01, 2007

Selenium inhibits pancreatic cancer cell growth in hamsters. Jul 15, 1990

Sesamol exhibits anti-depressant properties.Apr 01, 2011

Sesamol protects against chemically-induced oxidative renal injury in rats. Apr 01, 2009

Sesamol protects against myocardial infarction. Jan 01, 2010

Sesamol reduces total oxidant status, malondialdehyde levels and inhibits cataract formation.Nov 30, 2017

These results validate the use of saffron as a treatment against diabetes mellitus and its vascular complications.Mar 31, 2017

Trans-resveratrol at low doses may have a therapeutic role in preventing liver damage during surgery or transplantation. Oct 01, 2008

Turmeric extract and curcumin can protect the liver from acute carbon tetrachloride induced injury.Jan 31, 2017

Virgin coconut oil has the potential to be used as a memory enhancer.Nov 30, 2017

Whey protein hydrolysates increase liver glutathione synthesis in mice.Jan 01, 2005

Whey supplementation may improve wound healing.Mar 01, 2008

Zinc and selenium protects against benzene toxicity in rats.Apr 21, 2011

Cinnamaldehyde enhances detoxification by increasing phase 2 enzyme expression. May 11, 2011

Coffee may exert its chemopreventive properties through metabolism and detoxification of xenobiotics.Jan 01, 2005

Dandelion extract inhibits lipopolysaccharide-induced oxidative stress and nitric oxide production associated with inflammation. Jan 27, 2011

Dandelion extracts especially leaf and flower extracts are potent protective agents against UVB damage.Dec 31, 2014

EGCG has antifibrogenic activity relevant to the prevention and treatment of liver fibrosis. Jul 01, 2006

l-Arginine supplementation induces glutathione synthesis in interscapular brown adipose tissue.Dec 10, 2009

Melatonin may be an effectively protective agent against H2O2-induced oxidative stress and apoptosis in bone marrow mesenchymal stem cells.Dec 22, 2016

N-acetyl cysteine has antiproliferative on pancreatic cancer cells. Dec 01, 2000

Resveratrol reduces endothelial oxidative stress.May 01, 2008

Silymarin can effectively alleviate acrylamide induced neurotoxicity in PC12 cells.Mar 31, 2017

Sulforaphane treatment may present a strategy for enhancing the cellular defense mechanisms in skin.Feb 01, 2010

This review summarises the many health benefits of Sulforaphane as a antioxidant dietary supplement.May 04, 2015

Various polyphenols exhibit potential anti-obesity activity. Jan 26, 2011

Whey protein concentrate may positively modulate glutathione in cancer treatment.Nov 01, 2000

Whey protein may exert its anti-carcinogenic effect by enhancing glutathione concentrations.May 01, 1991

Zinc may have radioprotective properties against radioiodine-131 toxicity in red blood cells.Oct 01, 2005

Broccoli sprouts correct phase 2 enzyme expression in human prostate cancer cells.Sep 01, 2001

Phellodendron amurense has the highest glutathione S-transferase activiting activity of 265 kinds of medicinal plants tested.Sep 01, 2006

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Glutathione Upregulation

View the Evidence:
69 Abstracts with Glutathione Upregulation Research