Glutathione Upregulation

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40 Substances Researched for Glutathione Upregulation
NameACCKFocus
Whey948Locked
Selenium314Locked
Sulforaphane312Locked
Coffee211Locked
MSM (Methylsulfonylmethane)110Locked
Sesamol36Locked
Astaxanthin24Locked
Ginger24Locked
Resveratrol34Locked
Arginine23Locked
EGCG (Epigallocatechin gallate)23Locked
Zinc23Locked
Catechin 12Locked
Chlorella (Algae)12Locked
Chrysin12Locked
Cinnamon12Locked
Curcumin12Locked
Dandelion 22Locked
Ellagic Acid12Locked
Ferulic acid12Locked
Green Tea12Locked
Holy Basil12Locked
Loquat Seeds12Locked
Moringa oleifera12Locked
Nettle12Locked
Olive leaf extract12Locked
Probiotics12Locked
Pycnogenol (Pine Bark)12Locked
Rhodiola (Tibetan Ginseng)12Locked
Rosemary12Locked
Cinnamaldehyde11Locked
Flavonoids11Locked
NAC (N-acetyl-L-cysteine)11Locked
P-Coumaric Acid11Locked
Polyphenols11Locked
Quercetin11Locked
Stilbenes11Locked
Broccoli10Locked
Nexrutine (Phellodendrom)10Locked
Sprouts10Locked
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View the Evidence:
77 Abstracts with Glutathione Upregulation Research

[+]

Coffee (especially dark roast) reduces body weight and restores red blood cell vitamin E and glutathione concentrations in healthy volunteers.Aug 02, 2011

Pubmed Data : Mol Nutr Food Res. 2011 Aug 2. Epub 2011 Aug 2. PMID: 21809439
Article Published Date : Aug 02, 2011
Study Type : Human Study
Additional Links
Substances : Coffee
Diseases : Overweight , Oxidative Stress, Vitamin E Deficiency
Pharmacological Actions : Antioxidants, Glutathione Upregulation
[+]

Grape seed extract for eight weeks had beneficial effects on the plasma GSH, MDA levels, and markers of insulin metabolism of female volleyball players.Aug 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran Red Crescent Med J. 2016 Sep ;18(9):e31314. Epub 2016 Jul 17. PMID: 28144458
Article Published Date : Aug 31, 2016
Study Type : Human Study
Additional Links
Substances : Grape Seed Extract
Diseases : Oxidative Stress
Therapeutic Actions : Exercise
Pharmacological Actions : Antioxidants, Glutathione Upregulation , Malondialdehyde Down-regulation
[+]

Improved glutathione status in young adult patients with cystic fibrosis supplemented with whey protein.Dec 01, 2003

Pubmed Data : J Cyst Fibros. 2003 Dec;2(4):195-8. PMID: 15463873
Article Published Date : Dec 01, 2003
Study Type : Human Study
Additional Links
Substances : Whey
Diseases : Cystic Fibrosis, Lung Diseases, Oxidative Stress
Pharmacological Actions : Antioxidants, Glutathione Upregulation
[+]

Oral sulforaphane safely and effectively induces mucosal Phase II enzyme expression in the upper airway of human subjects. Mar 01, 2009

Pubmed Data : Clin Immunol. 2009 Mar;130(3):244-51. Epub 2008 Nov 22. PMID: 19028145
Article Published Date : Mar 01, 2009
Study Type : Human Study
Additional Links
Substances : Sulforaphane
Diseases : COPD, Cystic Fibrosis, Glutathione Deficiency , Lung Diseases, Pulmonary Fibrosis, Respiratory Diseases
Pharmacological Actions : Antioxidants, Glutathione Upregulation , Phase II Detoxification Enzyme Inducer
Additional Keywords : Isothiocyanates
[+]

Oral supplementation of MSM has alleviating effects on known markers of oxidative stress following acute bouts of exercise in healthy young men.Oct 01, 2011

Pubmed Data : J Pharm Pharmacol. 2011 Oct ;63(10):1290-4. Epub 2011 Aug 1. PMID: 21899544
Article Published Date : Oct 01, 2011
Study Type : Human Study
Additional Links
Substances : MSM (Methylsulfonylmethane)
Diseases : Athletic Performance: Recovery , Oxidative Stress
Pharmacological Actions : Antioxidants, Glutathione Upregulation
[+]

Oral supplementation with liposomal glutathione elevates body stores of glutathione and markers of immune function.Dec 31, 2017

Pubmed Data : Eur J Clin Nutr. 2018 Jan ;72(1):105-111. Epub 2017 Aug 30. PMID: 28853742
Article Published Date : Dec 31, 2017
Study Type : Human Study
Additional Links
Substances : Glutathione
Diseases : Glutathione Deficiency
Pharmacological Actions : Glutathione Upregulation , Immunostimulatory
[+]

Pressurized whey protein isolate can increase lymphocyte glutathione levels by 24%Sep 01, 2007

Pubmed Data : Int J Food Sci Nutr. 2007 Sep;58(6):429-36. PMID: 17710587
Article Published Date : Sep 01, 2007
Study Type : Human Study
Additional Links
Substances : Whey
Diseases : Immune Disorders: Low Immune Function
Pharmacological Actions : Glutathione Upregulation
[+]

Selenium glycinate supplementation increases blood glutathione peroxidase activities and decreases prostate-specific antigen readings in middle-aged US men.Feb 01, 2011

Pubmed Data : Nutr Res. 2011 Feb;31(2):165-8. Epub 2011 Feb 12. PMID: 21419321
Article Published Date : Feb 01, 2011
Study Type : Human Study
Additional Links
Substances : Selenium
Diseases : Glutathione Deficiency , Prostate: PSA Doubling
Pharmacological Actions : Glutathione Upregulation
[+]

Supplementation with whey proteins persistently increased plasma glutathione levels in patients with advanced HIV-infection.Feb 01, 2002

Pubmed Data : Eur J Nutr. 2002 Feb;41(1):12-8. PMID: 11990003
Article Published Date : Feb 01, 2002
Study Type : Human Study
Additional Links
Substances : Whey
Diseases : AIDS, Glutathione Deficiency , HIV Infections
Pharmacological Actions : Glutathione Upregulation
[+]

Whey protein concentrate supplementation can stimulate glutathione synthesis and, possibly, decrease the occurence of associated co-infections.Feb 01, 2006

Pubmed Data : J Trop Pediatr. 2006 Feb;52(1):34-8. Epub 2005 Jul 13. PMID: 16014759
Article Published Date : Feb 01, 2006
Study Type : Human Study
Additional Links
Substances : Whey
Diseases : Childhood Infections, Glutathione Deficiency , HIV Infections
Pharmacological Actions : Glutathione Upregulation
[+]

6-Shogaol can alleviate allergic dermatitis-like skin lesions.Oct 31, 2016

Pubmed Data : Toxicol Appl Pharmacol. 2016 Nov 1 ;310:51-59. Epub 2016 Aug 22. PMID: 27562088
Article Published Date : Oct 31, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Gingerol
Diseases : Dermatitis
Pharmacological Actions : Antioxidants, Glutathione Upregulation , Heme oxygenase-1 up-regulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Ajoene restored behavioral patterns and liver glutathione level in morphine treated C57BL6 mice.Dec 31, 2016

Pubmed Data : Arch Pharm Res. 2017 Jan ;40(1):106-111. Epub 2016 Oct 28. PMID: 27796936
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Garlic
Diseases : Morphine Tolerance/Dependence
Pharmacological Actions : Glutathione Upregulation , Hepatoprotective
[+]

Alpha mangostin attenuated hepatic steatosis in high fat-diet fed rats potentially through enhanced cellular antioxidant capacity.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Metab (Lond). 2016 ;13:88. Epub 2016 Dec 1. PMID: 27980597
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Mangosteen
Diseases : High Fat Diet, Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Catalase Up-Regulation, Glutathione Upregulation , Hepatoprotective, Superoxide Dismutase Up-regulation
[+]

Astaxanthin attenuates environmental tobacco smoke-induced cognitive deficits.Jan 02, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mar Drugs. 2019 Jan 3 ;17(1). Epub 2019 Jan 3. PMID: 30609815
Article Published Date : Jan 02, 2019
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Cognitive Decline/Dysfunction, Tobacco Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Catalase Up-Regulation, Glutathione Upregulation , Interleukin-6 Downregulation, Neuroprotective Agents, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Astaxanthin improves diabetic complications associated wtih dental pulp tissue. Nov 01, 2010

Pubmed Data : Int Endod J. 2010 Nov;43(11):959-67. PMID: 20546046
Article Published Date : Nov 01, 2010
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Diabetes: Dental Problems, Diabetic Complications
Pharmacological Actions : Antioxidants, Glutathione Upregulation
[+]

Astaxanthin restores the enzymatic antioxidant profile in salivary gland of alloxan-induced diabetic rats.Jul 01, 2010

Pubmed Data : Arch Oral Biol. 2010 Jul;55(7):479-85. PMID: 20510163
Article Published Date : Jul 01, 2010
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Diabetes: Oxidative Stress, Oxidative Stress
Pharmacological Actions : Antioxidants, Glutathione Upregulation
[+]

Brahmi vati may be used to treat seizures associated with schizophrenia and related memory loss.Feb 28, 2018

Pubmed Data : Epilepsy Behav. 2018 Mar ;80:144-151. Epub 2018 Feb 2. PMID: 29414544
Article Published Date : Feb 28, 2018
Study Type : Animal Study
Additional Links
Substances : Bacopa
Diseases : Memory Disorders, Schizophrenia
Pharmacological Actions : Glutathione Upregulation , Neuroprotective Agents
Problem Substances : Amphetamine
[+]

Chlorella vulgaris extract ameliorates carbon tetrachloride-induced acute hepatic injury in mice.Jul 07, 2011

Pubmed Data : Exp Toxicol Pathol. 2011 Jul 7. Epub 2011 Jul 7. PMID: 21741806
Article Published Date : Jul 07, 2011
Study Type : Animal Study
Additional Links
Substances : Chlorella (Algae)
Diseases : Chemically-Induced Liver Damage, Liver Damage
Pharmacological Actions : Glutathione Upregulation , Hepatoprotective
[+]

Chrysin protects against free radical-mediated oxidative stress in rats with ethanol-induced liver injury. Jun 01, 2009

Pubmed Data : J Pharm Pharmacol. 2009 Jun;61(6):809-17. PMID: 19505373
Article Published Date : Jun 01, 2009
Study Type : Animal Study
Additional Links
Substances : Chrysin
Diseases : Alcohol Toxicity , Alcoholic Liver Disease, Liver Cirrhosis: Alcoholic
Pharmacological Actions : Glutathione Upregulation , Hepatoprotective
[+]

Cinnamon and rhodiola have significant blood sugar lowering and antioxidant activity.Jan 01, 2006

Pubmed Data : Biofactors. 2006;26(3):209-19. PMID: 16971752
Article Published Date : Jan 01, 2006
Study Type : Animal Study
Additional Links
Substances : Cinnamon, Rhodiola (Tibetan Ginseng)
Diseases : Diabetes Mellitus: Type 1, Diabetes Mellitus: Type 2
Pharmacological Actions : Antioxidants, Glutathione Upregulation
[+]

Coenzyme Q10 has a coloprotective effect against experimentally induced ulcerative colitis.Jan 02, 2017

Pubmed Data : Inflammopharmacology. 2017 Jan 3. Epub 2017 Jan 3. PMID: 28050757
Article Published Date : Jan 02, 2017
Study Type : Animal Study
Additional Links
Substances : Coenzyme Q10
Diseases : Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Catalase Up-Regulation, Glutathione Upregulation , Heme oxygenase-1 up-regulation, Malondialdehyde Down-regulation, Nrf2 activation, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Dose Response
[+]

Curcumin treatment alleviates the effects of glutathione depletion in vitro and in vivo, indicating its value for Parkinson disease. Mar 01, 2008

Pubmed Data : Free Radic Biol Med. 2008 Mar 1;44(5):907-17. Epub 2007 Dec 4. PMID: 18166164
Article Published Date : Mar 01, 2008
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Oxidative Stress, Parkinson's Disease
Pharmacological Actions : Antineoplastic Agents, Glutathione Upregulation , Neuroprotective Agents
[+]

EGCG protects against muscle wasting disease, in a mouse model. Apr 14, 2010

Pubmed Data : J Agric Food Chem. 2010 Apr 14;58(7):4523-8. PMID: 19322813
Article Published Date : Apr 14, 2010
Study Type : Animal Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Muscle Atrophy , Muscular Dystrophies
Pharmacological Actions : Glutathione Upregulation
[+]

Embelia ribes extract reduces high fat diet and low dose streptozotocin-induced diabetic nephrotoxicity in rats.Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : EXCLI J. 2013 ;12:858-71. Epub 2013 Sep 24. PMID: 26622220
Article Published Date : Dec 31, 2012
Study Type : Animal Study
Additional Links
Substances : False Black Pepper
Diseases : Diabetes Mellitus: Type 2, Diabetic Nephropathy, Lipid Peroxidation
Pharmacological Actions : Antihypertensive Agents, Antioxidants, Catalase Up-Regulation, Glutathione Upregulation , Insulin Sensitizers, Renoprotective, Superoxide Dismutase Up-regulation
Additional Keywords : Plant Extracts
[+]

Fresh nettle leaves are a natural protective herb that may play a beneficial role in the prevention of Hg intoxication.Nov 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Vet World. 2015 Dec ;8(12):1458-65. PMID: 27047060
Article Published Date : Nov 30, 2015
Study Type : Animal Study
Additional Links
Substances : Nettle
Diseases : Mercury Poisoning
Pharmacological Actions : Glutathione Upregulation
Additional Keywords : Herbal Teas, Methylmercury
Problem Substances : Mercury
[+]

Ginger protects against dichlorvos and lindane induced oxidative stress in rat brain. Jan 01, 2012

Pubmed Data : Pharmacognosy Res. 2012 Jan ;4(1):27-32. PMID: 22224058
Article Published Date : Jan 01, 2012
Study Type : Animal Study
Additional Links
Substances : Ginger
Diseases : Brain Damage
Pharmacological Actions : Glutathione Upregulation , Neuroprotective Agents, Superoxide Dismutase Up-regulation
Problem Substances : Dichlorvos, Lindane
[+]

Ginger protects against liver fibrosis.Jan 01, 2011

Pubmed Data : Nutr Metab (Lond). 2011 ;8:40. Epub 2011 Jun 20. PMID: 21689445
Article Published Date : Jan 01, 2011
Study Type : Animal Study
Additional Links
Substances : Ginger
Diseases : ALT: Elevated, AST: Elevated, Liver Fibrosis
Pharmacological Actions : Glutathione Upregulation , Malonaldehyde (MDA) Down-Regulation, Renoprotective, Superoxide Dismutase Up-regulation
[+]

Green tea catechin prevents the decline of glutathione peroxidase activity and protein oxidative damage in aging mouse brain.Aug 01, 2007

Pubmed Data : Biogerontology. 2007 Aug;8(4):423-30. Epub 2007 Feb 20. PMID: 17310319
Article Published Date : Aug 01, 2007
Study Type : Animal Study
Additional Links
Substances : Catechin , Green Tea
Diseases : Aging, Aging: Brain , Oxidative Stress
Pharmacological Actions : Antioxidants, Glutathione Upregulation , Neuroprotective Agents
[+]

Hesperidin and chrysin alleviated the renal injury induced by colistin via anti-oxidant and anti-inflammatory activities.Nov 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2018 Dec ;108:1607-1616. Epub 2018 Oct 10. PMID: 30372863
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Chrysin, Hesperidin
Diseases : Kidney Damage: Drug-Induced
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Catalase Up-Regulation, Glutathione Upregulation , Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Renoprotective, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Holy basil (O. sanctum) protects against radiation injury through modulating glutathione and antioxidant enzymes. Mar 01, 1999

Pubmed Data : Indian J Exp Biol. 1999 Mar;37(3):262-8. PMID: 10641157
Article Published Date : Mar 01, 1999
Study Type : Animal Study
Additional Links
Substances : Holy Basil
Diseases : Radiation Induced Illness
Pharmacological Actions : Glutathione Upregulation , Radioprotective
[+]

L-arginine protects against pulmonary oxidative stress and antioxidant defenses during exhaustive exercise in rats.Aug 01, 2005

Pubmed Data : Acta Pharmacol Sin. 2005 Aug;26(8):992-9. PMID: 16038634
Article Published Date : Aug 01, 2005
Study Type : Animal Study
Additional Links
Substances : Arginine
Diseases : Exercise-Induced Tissue Damage, Lipid Peroxidation, Lung Damage, Oxidative Stress
Pharmacological Actions : Antioxidants, Glutathione Upregulation , Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation
[+]

Loquat seed inhibits oxidative stress associated wtih adriamycin-induced nephropathy. Dec 01, 2004

Pubmed Data : Biol Pharm Bull. 2004 Dec;27(12):1961-4. PMID: 15577213
Article Published Date : Dec 01, 2004
Study Type : Animal Study
Additional Links
Substances : Loquat Seeds
Diseases : Chemotherapy-Induced Toxicity: Adriamycin, Lipid Peroxidation, Nephropathy, Oxidative Stress
Pharmacological Actions : Glutathione Upregulation , Renoprotective
Additional Keywords : Drug: Doxorubicin, Plant Extracts
[+]

Lychee pulp phenolics protect the liver against restraint stress-induced damage by scavenging free radicals and modulating mitochondrial dysfunction.Dec 31, 2015

Pubmed Data : Food Funct. 2016 Jan ;7(1):508-15. PMID: 26569420
Article Published Date : Dec 31, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Litchi
Diseases : Liver Damage, Mitochondrial Dysfunction , Oxidative Stress
Pharmacological Actions : Antioxidants, Catalase Up-Regulation, Glutathione Upregulation , Hepatoprotective, Superoxide Dismutase Up-regulation
Additional Keywords : Antioxidants, Catalase Up-Regulation, Litchi, liver damage, Mitochondrial Dysfunction, oxidative stress, Plant Extracts
[+]

Moringa oleifera prevents acetaminophen induced liver injury through restoration of glutathione level. Aug 01, 2008

Pubmed Data : Food Chem Toxicol. 2008 Aug;46(8):2611-5. Epub 2008 Apr 25. PMID: 18514995
Article Published Date : Aug 01, 2008
Study Type : Animal Study
Additional Links
Substances : Moringa oleifera
Diseases : Acetaminophen (Tylenol) Toxicity
Pharmacological Actions : Glutathione Upregulation
[+]

N-acetylcysteine and thymoquinone have renoprotective effects of against the toxicity of fluoride via multiple mechanisms.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2018 ;2018:5614803. Epub 2018 Jun 28. PMID: 30050936
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Cysteine (see N-Acetylcysteine), Thymoquinone
Diseases : Fluoride Toxicity , Kidney Damage: Chemically-Induced
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Glutathione Upregulation , Nrf2 activation, Renoprotective, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Sodium Fluoride
[+]

Olive leaf extract ameliorates gentamicin nephrotoxicity via antioxidant activity, increase of renal glutathione content, and increase of renal antioxidant enzymes activity, except for glutathione peroxidase.Jan 01, 2012

Pubmed Data : Iran J Kidney Dis. 2012 Jan ;6(1):25-32. PMID: 22218116
Article Published Date : Jan 01, 2012
Study Type : Animal Study
Additional Links
Substances : Olive leaf extract
Diseases : Chemotherapy-Induced Toxicity: Gentamicin
Pharmacological Actions : Antioxidants, Glutathione Upregulation , Renoprotective
Problem Substances : Gentamicin
Adverse Pharmacological Actions : Nephrotoxic, Oxidant
[+]

Oral administration of Ellagic acid and Ferulic acid may ameliorate gamma radiation and aluminium chloride induced oxidative damage.Jul 15, 2016

Pubmed Data : Life Sci. 2016 Jul 16. Epub 2016 Jul 16. PMID: 27436544
Article Published Date : Jul 15, 2016
Study Type : Animal Study
Additional Links
Substances : Ellagic Acid, Ferulic acid
Diseases : Chemotherapy and Radiation Toxicity
Pharmacological Actions : Antioxidants, Catalase Up-Regulation, Glutathione Upregulation , Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation
Problem Substances : Aluminum Chloride
[+]

Oral supplementation with whey proteins increases plasma glutathione levels of HIV-infected patients.Feb 01, 2001

Pubmed Data : Eur J Clin Invest. 2001 Feb;31(2):171-8. PMID: 11168457
Article Published Date : Feb 01, 2001
Study Type : Animal Study
Additional Links
Substances : Whey
Diseases : AIDS, Glutathione Deficiency , HIV Infections
Pharmacological Actions : Antioxidants, Glutathione Upregulation
[+]

Parsley is effective in reducing stress-induced gastric injury by supporting the cellular antioxidant defence system.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Balkan Med J. 2017 Jan ;34(1):53-59. Epub 2017 Jan 5. PMID: 28251024
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Parsley
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants, Catalase Up-Regulation, Gastroprotective, Glutathione Upregulation , Superoxide Dismutase Up-regulation
[+]

Photobiomodulation therapy reduces apoptotic factors and increases glutathione levels in a neuropathic pain model.Nov 30, 2016

Pubmed Data : Lasers Med Sci. 2016 Dec ;31(9):1863-1869. Epub 2016 Sep 17. PMID: 27640000
Article Published Date : Nov 30, 2016
Study Type : Animal Study
Additional Links
Diseases : Neuropathic Pain
Therapeutic Actions : Laser Treatment: Low-Level
Pharmacological Actions : Anti-Apoptotic, Glutathione Upregulation
[+]

Pinus massoniana bark extract treatment prevents hydrogen peroxide and carbon tetrachloride induced liver damage.Dec 31, 2009

Pubmed Data : Am J Chin Med. 2010 ;38(5):909-19. PMID: 20821822
Article Published Date : Dec 31, 2009
Study Type : Animal Study
Additional Links
Substances : Pine Bark Extract
Diseases : Chemically-Induced Liver Damage, Hydrogen Peroxide Induced Toxicity, Oxidative Stress
Pharmacological Actions : Antioxidants, Glutathione Upregulation , Hepatoprotective, Malondialdehyde Down-regulation
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Polysaccharides from Ganoderma lucidum played a positive protective role in the pulmonary fibrosis.Oct 31, 2016

Pubmed Data : Int J Biol Macromol. 2016 Nov ;92:278-281. Epub 2016 Aug 2. PMID: 27381587
Article Published Date : Oct 31, 2016
Study Type : Animal Study
Additional Links
Substances : Reishi Mushroom
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Antioxidants, Catalase Up-Regulation, Glutathione Upregulation , Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation
Additional Keywords : Polysaccharides
[+]

Probiotics enhance glutathione biosynthesis and reduce oxidative stress in experimental acute pancreatitis. Nov 01, 2008

Pubmed Data : Am J Physiol Gastrointest Liver Physiol. 2008 Nov;295(5):G1111-21. Epub 2008 Oct 2. PMID: 18832452
Article Published Date : Nov 01, 2008
Study Type : Animal Study
Additional Links
Substances : Probiotics
Diseases : Pancreatitis
Pharmacological Actions : Glutathione Upregulation
[+]

Pueraria mirifica and miroestrol as promising alternative medicine candidates for hormone replacement therapy of estradiol.Feb 28, 2013

Pubmed Data : J Pharm Pharmacol. 2013 Mar ;65(3):447-56. Epub 2012 Nov 22. PMID: 23356854
Article Published Date : Feb 28, 2013
Study Type : Animal Study
Additional Links
Substances : Pueraria mirifica
Pharmacological Actions : Antioxidants, Glutathione Upregulation , Superoxide Dismutase Up-regulation
Additional Keywords : Antioxidants, Ovariectomy-Induced Changes, Plant Extracts, Pueraria mirifica
[+]

Pycnogenol treatment attenuated α-chlorohydrin-induced spermatotoxicity through antioxidant and antiapoptotic effects.Feb 28, 2014

Pubmed Data : Phytother Res. 2014 Mar ;28(3):451-7. Epub 2013 Jun 21. PMID: 23788506
Article Published Date : Feb 28, 2014
Study Type : Animal Study
Additional Links
Substances : Pycnogenol (Pine Bark)
Diseases : Lipid Peroxidation, Sperm Quality: Low
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Glutathione Upregulation , Malondialdehyde Down-regulation
Additional Keywords : Plant Extracts
[+]

Rosemary attenuates radiation-induced toxicity.Oct 01, 2007

Pubmed Data : Phytomedicine. 2007 Oct;14(10):701-5. Epub 2007 Apr 12. PMID: 17433646
Article Published Date : Oct 01, 2007
Study Type : Animal Study
Additional Links
Substances : Rosemary
Diseases : Lipid Peroxidation, Radiation Induced Illness
Pharmacological Actions : Glutathione Upregulation , Radioprotective
Additional Keywords : Plant Extracts
[+]

Selenium inhibits pancreatic cancer cell growth in hamsters. Jul 15, 1990

Pubmed Data : Int J Cancer. 1990 Jul 15;46(1):95-100. PMID: 2365502
Article Published Date : Jul 15, 1990
Study Type : Animal Study
Additional Links
Substances : Selenium
Diseases : Prostate Cancer
Pharmacological Actions : Glutathione Upregulation
[+]

Sesamol exhibits anti-depressant properties.Apr 01, 2011

Pubmed Data : Psychopharmacology (Berl). 2011 Apr ;214(4):819-28. Epub 2010 Nov 20. PMID: 21103863
Article Published Date : Apr 01, 2011
Study Type : Animal Study
Additional Links
Substances : Sesamol
Diseases : Depression, Lipid Peroxidation
Pharmacological Actions : Antidepressive Agents, Catalase Up-Regulation, Glutathione Upregulation , Superoxide Dismutase Up-regulation
[+]

Sesamol protects against chemically-induced oxidative renal injury in rats. Apr 01, 2009

Pubmed Data : Basic Clin Pharmacol Toxicol. 2009 Apr ;104(4):316-21. Epub 2009 Feb 27. PMID: 19281599
Article Published Date : Apr 01, 2009
Study Type : Animal Study
Additional Links
Substances : Sesamol
Diseases : Kidney Damage, Lipid Peroxidation, Oxidative Stress
Pharmacological Actions : Antioxidants, Glutathione Upregulation , Renoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Sesamol protects against myocardial infarction. Jan 01, 2010

Pubmed Data : Redox Rep. 2010 ;15(1):36-42. PMID: 20196927
Article Published Date : Jan 01, 2010
Study Type : Animal Study
Additional Links
Substances : Sesamol
Diseases : Lipid Peroxidation, Myocardial Infarction: Prevention
Pharmacological Actions : Antioxidants, Glutathione Upregulation , Mitochondrial Superoxide Dismutase Upregulation
[+]

Sesamol reduces total oxidant status, malondialdehyde levels and inhibits cataract formation.Nov 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Turk J Ophthalmol. 2017 Dec ;47(6):309-314. Epub 2017 Dec 27. PMID: 29326846
Article Published Date : Nov 30, 2017
Study Type : Animal Study
Additional Links
Substances : Sesamol
Diseases : Cataract
Pharmacological Actions : Antioxidants, Glutathione Upregulation , Malondialdehyde Down-regulation
[+]

These results validate the use of saffron as a treatment against diabetes mellitus and its vascular complications.Mar 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Indian Heart J. 2017 Mar - Apr;69(2):151-159. Epub 2016 Sep 25. PMID: 28460761
Article Published Date : Mar 31, 2017
Study Type : Animal Study
Additional Links
Substances : Saffron
Diseases : Diabetic Complications
Pharmacological Actions : Anticholesteremic Agents, Antioxidants, Catalase Up-Regulation, Glutathione Upregulation , Hypoglycemic Agents, Hypolipidemic, Immunomodulatory, Malondialdehyde Down-regulation, Nitric Oxide Inhibitor, Superoxide Dismutase Up-regulation
Additional Keywords : Plant Extracts
[+]

Trans-resveratrol at low doses may have a therapeutic role in preventing liver damage during surgery or transplantation. Oct 01, 2008

Pubmed Data : J Ocul Pharmacol Ther. 2008 Oct;24(5):439-44. PMID: 18383089
Article Published Date : Oct 01, 2008
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Organ Transplantation: Liver, Surgery: Liver, Surgery: Recovery
Pharmacological Actions : Glutathione Upregulation
[+]

Turmeric extract and curcumin can protect the liver from acute carbon tetrachloride induced injury.Jan 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Res Notes. 2017 Feb 1 ;10(1):77. Epub 2017 Feb 1. PMID: 28143589
Article Published Date : Jan 31, 2017
Study Type : Animal Study
Additional Links
Substances : Curcumin, Turmeric
Diseases : Chemically-Induced Liver Damage, Lipid Peroxidation, Oxidative Stress
Pharmacological Actions : Glutathione Upregulation , Hepatoprotective, Superoxide Dismutase Up-regulation
Additional Keywords : Phytotherapy, Plant Extracts
Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

Virgin coconut oil has the potential to be used as a memory enhancer.Nov 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharm Biol. 2017 Dec ;55(1):825-832. PMID: 28118770
Article Published Date : Nov 30, 2017
Study Type : Animal Study
Additional Links
Substances : Virgin Coconut Oil
Diseases : Memory Disorders
Pharmacological Actions : Acetylcholinesterase Down-Regulation, Antioxidants, Catalase Up-Regulation, Glutathione Upregulation , Malondialdehyde Down-regulation, Neuroprotective Agents, Nitric Oxide Inhibitor, Superoxide Dismutase Up-regulation
[+]

Whey protein hydrolysates increase liver glutathione synthesis in mice.Jan 01, 2005

Pubmed Data : J Med Food. 2005;8(3):337-42. PMID: 16176144
Article Published Date : Jan 01, 2005
Study Type : Animal Study
Additional Links
Substances : Whey
Diseases : Glutathione Deficiency
Pharmacological Actions : Glutathione Upregulation
[+]

Whey supplementation may improve wound healing.Mar 01, 2008

Pubmed Data : Int J Vitam Nutr Res. 2008 Mar;78(2):70-3. PMID: 18791975
Article Published Date : Mar 01, 2008
Study Type : Animal Study
Additional Links
Substances : Whey
Diseases : Wound Healing
Pharmacological Actions : Antioxidants, Glutathione Upregulation , Interleukin-1 beta downregulation
[+]

Zinc and selenium protects against benzene toxicity in rats.Apr 21, 2011

Pubmed Data : Toxicol Ind Health. 2011 Apr 21. Epub 2011 Apr 21. PMID: 21511895
Article Published Date : Apr 21, 2011
Study Type : Animal Study
Additional Links
Substances : Selenium, Zinc
Diseases : Benzene Toxicity
Pharmacological Actions : Catalase Up-Regulation, Glutathione Upregulation , GSH-Px Up-Regulation, Malonaldehyde (MDA) Down-Regulation, Superoxide Dismutase Up-regulation
[+]

Alpha-tocopherol shows immunoprotective effects in Deltamethrin induced splenic and thymic apoptosis.Jul 31, 2018

Pubmed Data : Endocr Metab Immune Disord Drug Targets. 2018 Aug 1. Epub 2018 Aug 1. PMID: 30068286
Article Published Date : Jul 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Vitamin E: alpha tocopherol
Diseases : Pesticide Toxicity
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Glutathione Upregulation
Problem Substances : Deltamethrin, Pesticides
[+]

Cinnamaldehyde enhances detoxification by increasing phase 2 enzyme expression. May 11, 2011

Pubmed Data : J Agric Food Chem. 2011 May 11;59(9):5164-71. Epub 2011 Apr 15. PMID: 21469739
Article Published Date : May 11, 2011
Study Type : In Vitro Study
Additional Links
Substances : Cinnamaldehyde
Diseases : Intoxication
Pharmacological Actions : Glutathione Upregulation , Phase II Detoxification Enzyme Inducer
[+]

Coffee may exert its chemopreventive properties through metabolism and detoxification of xenobiotics.Jan 01, 2005

Pubmed Data : Methods Enzymol. 2005;401:307-41. PMID: 16399395
Article Published Date : Jan 01, 2005
Study Type : Review
Additional Links
Substances : Coffee, Flavonoids, Polyphenols
Diseases : Cancers: All
Pharmacological Actions : Chemopreventive, Glutathione Upregulation
Additional Keywords : Plant Extracts, Xenobiotic Metabolism
[+]

Dandelion extract inhibits lipopolysaccharide-induced oxidative stress and nitric oxide production associated with inflammation. Jan 27, 2011

Pubmed Data : J Ethnopharmacol. 2011 Jan 27;133(2):834-42. Epub 2010 Nov 11. PMID: 21075189
Article Published Date : Jan 27, 2011
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Glutathione Deficiency , Lipopolysaccharide-Induced Toxicity, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Glutathione Upregulation , NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Superoxide Dismutase Up-regulation
[+]

Dandelion extracts especially leaf and flower extracts are potent protective agents against UVB damage.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2015 ;2015:619560. Epub 2015 Oct 20. PMID: 26576225
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Ultraviolet Radiation Induced Damage
Pharmacological Actions : Antioxidants, Glutathione Upregulation
Additional Keywords : Plant Extracts
[+]

EGCG has antifibrogenic activity relevant to the prevention and treatment of liver fibrosis. Jul 01, 2006

Pubmed Data : Lab Invest. 2006 Jul;86(7):697-709. Epub 2006 May 8. PMID: 16682975
Article Published Date : Jul 01, 2006
Study Type : In Vitro Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Fibrosis: Liver, Liver Fibrosis
Pharmacological Actions : Glutathione Upregulation
[+]

l-Arginine supplementation induces glutathione synthesis in interscapular brown adipose tissue.Dec 10, 2009

Pubmed Data : Chem Biol Interact. 2009 Dec 10;182(2-3):204-12. Epub 2009 Jul 22. PMID: 19631198
Article Published Date : Dec 10, 2009
Study Type : In Vitro Study
Additional Links
Substances : Arginine
Diseases : Glutathione Deficiency
Pharmacological Actions : Glutathione Upregulation
[+]

Melatonin may be an effectively protective agent against H2O2-induced oxidative stress and apoptosis in bone marrow mesenchymal stem cells.Dec 22, 2016

Pubmed Data : Can J Physiol Pharmacol. 2016 Dec 23. Epub 2016 Dec 23. PMID: 28177678
Article Published Date : Dec 22, 2016
Study Type : In Vitro Study
Additional Links
Substances : Melatonin
Diseases : Hydrogen Peroxide Induced Toxicity
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Catalase Up-Regulation, Glutathione Upregulation , Interleukin-6 Downregulation, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Mesenchymal Stem Cells
[+]

N-acetyl cysteine has antiproliferative on pancreatic cancer cells. Dec 01, 2000

Pubmed Data : Hum Cell. 2000 Dec;13(4):213-20. PMID: 11329937
Article Published Date : Dec 01, 2000
Study Type : In Vitro Study
Additional Links
Substances : NAC (N-acetyl-L-cysteine)
Diseases : Pancreatic Cancer
Pharmacological Actions : Glutathione Upregulation
[+]

Resveratrol reduces endothelial oxidative stress.May 01, 2008

Pubmed Data : Phytochemistry. 2008 May;69(8):1732-8. Epub 2008 Apr 15. PMID: 20083859
Article Published Date : May 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol, Stilbenes
Diseases : Endothelial Dysfunction, Oxidative Stress
Pharmacological Actions : Antioxidants, Glutathione Peroxidase 1 (GPx1) Up-Regulation, Glutathione Upregulation , NADPH Oxidase Inhibitors, Superoxide Dismutase Up-regulation
[+]

Silymarin can effectively alleviate acrylamide induced neurotoxicity in PC12 cells.Mar 31, 2017

Pubmed Data : Food Chem Toxicol. 2017 Apr ;102:93-101. Epub 2017 Jan 27. PMID: 28137608
Article Published Date : Mar 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Silymarin
Diseases : Acrylamide-induced toxicity
Pharmacological Actions : Antioxidants, Glutathione Upregulation , Malondialdehyde Down-regulation, Neuroprotective Agents, Nrf2 activation
Problem Substances : Acrylamide
[+]

Sulforaphane treatment may present a strategy for enhancing the cellular defense mechanisms in skin.Feb 01, 2010

Pubmed Data : Exp Dermatol. 2010 Feb;19(2):137-44. Epub 2009 Jun 23. PMID: 19558496
Article Published Date : Feb 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Sulforaphane
Diseases : Aging Skin, Glutathione Deficiency , Skin Diseases
Pharmacological Actions : Anticarcinogenic Agents, Glutathione Upregulation , NF-kappaB Inhibitor
[+]

This review summarises the many health benefits of Sulforaphane as a antioxidant dietary supplement.May 04, 2015

Pubmed Data : Recent Pat Endocr Metab Immune Drug Discov. 2015 May 5. Epub 2015 May 5. PMID: 25944116
Article Published Date : May 04, 2015
Study Type : Review
Additional Links
Substances : Sulforaphane
Diseases : Cancers: All, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Anticarcinogenic Agents, Antioxidants, Glutathione Upregulation , Nrf2 activation
Additional Keywords : Detoxification, Dose Response, Epigenetic Modification
[+]

Various polyphenols exhibit potential anti-obesity activity. Jan 26, 2011

Pubmed Data : J Agric Food Chem. 2011 Jan 26;59(2):546-51. Epub 2010 Dec 27. PMID: 21186817
Article Published Date : Jan 26, 2011
Study Type : In Vitro Study
Additional Links
Substances : P-Coumaric Acid, Quercetin, Resveratrol
Diseases : Obesity
Pharmacological Actions : Glutathione Upregulation , Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Whey protein concentrate may positively modulate glutathione in cancer treatment.Nov 01, 2000

Pubmed Data : Anticancer Res. 2000 Nov-Dec;20(6C):4785-92. PMID: 11205219
Article Published Date : Nov 01, 2000
Study Type : Review
Additional Links
Substances : Whey
Diseases : Cancers: All, Male Urogenital Diseases, Urinary Tract Cancer, Urogenital Cancers
Pharmacological Actions : Antineoplastic Agents, Glutathione Upregulation
[+]

Whey protein may exert its anti-carcinogenic effect by enhancing glutathione concentrations.May 01, 1991

Pubmed Data : Cancer Lett. 1991 May 1;57(2):91-4. PMID: 2025891
Article Published Date : May 01, 1991
Study Type : Commentary
Additional Links
Substances : Whey
Diseases : Glutathione Deficiency
Pharmacological Actions : Anticarcinogenic Agents, Glutathione Upregulation
[+]

Zinc may have radioprotective properties against radioiodine-131 toxicity in red blood cells.Oct 01, 2005

Pubmed Data : Indian J Med Res. 2005 Oct;122(4):338-42. PMID: 16394327
Article Published Date : Oct 01, 2005
Study Type : In Vitro Study
Additional Links
Substances : Zinc
Diseases : Radiation-Induced Illness: Radioiodine (Iodine-131)
Pharmacological Actions : Glutathione Upregulation , Mitochondrial Superoxide Dismutase Upregulation, Radioprotective
[+]

Broccoli sprouts correct phase 2 enzyme expression in human prostate cancer cells.Sep 01, 2001

Pubmed Data : Cancer Epidemiol Biomarkers Prev. 2001 Sep;10(9):949-54. PMID: 11535546
Article Published Date : Sep 01, 2001
Additional Links
Substances : Broccoli, Sprouts
Diseases : Prostate Cancer
Pharmacological Actions : Glutathione Upregulation
[+]

Phellodendron amurense has the highest glutathione S-transferase activiting activity of 265 kinds of medicinal plants tested.Sep 01, 2006

Pubmed Data : Peptides. 2006 Sep;27(9):2069-74. Epub 2006 Apr 19. PMID: 16624447
Article Published Date : Sep 01, 2006
Additional Links
Substances : Nexrutine (Phellodendrom)
Pharmacological Actions : Glutathione Upregulation

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