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Article Count - 33
Cumulative Knowledge - 146

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Quick Summary: Current access displays 2 out of 14 associated Substances

Name	Cumulative Knowledge	Article Count	Focus Articles
Echinacea	65	12	Log in \| Sign up
Astaxanthin	15	4	Log in \| Sign up

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View the Evidence: Pharmacological Actions

Dietary consumption of Echinacea by mice afflicted with autoimmune (type I) diabetes results in long-lasting immunostimulation of NK cells only and no indication of increased autoimmunity.

Click here to read the entire abstract

Pubmed Data : Autoimmunity. 2005 Sep;38(6):453-61. PMID: 16278152

Article Published Date : Sep 01, 2005

Study Type : Meta Analysis

Additional Links

Substances : Echinacea : CK(469) : AC(88)

Diseases : Autoimmune Diseases : CK(5317) : AC(779), Diabetes Mellitus: Type 1 : CK(1107) : AC(218), Low Immune Function: Natural Killer Cells : CK(108) : AC(21)

Pharmacological Actions : Immunostimulatory : CK(143) : AC(33)

A proprietary extract from the echinacea plant (Echinacea purpurea) enhances systemic immune response during a common cold.

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2005 Aug;19(8):689-94. PMID: 16177972

Article Published Date : Aug 01, 2005

Study Type : Human Study

Additional Links

Substances : Echinacea : CK(469) : AC(88)

Diseases : Common Cold : CK(473) : AC(56)

Pharmacological Actions : Immunomodulatory : CK(536) : AC(142), Immunostimulatory : CK(143) : AC(33)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Acupuncture is effective to attenuate stress and stimulate lymphocyte proliferation in the elderly.

Click here to read the entire abstract

Pubmed Data : Neurosci Lett. 2010 Oct 22;484(1):47-50. Epub 2010 Aug 13. PMID: 20709154

Article Published Date : Oct 22, 2010

Study Type : Human Study

Additional Links

Diseases : Aging: Immunosenecence : CK(52) : AC(11), Anxiety Disorders : CK(659) : AC(82), Depression : CK(674) : AC(88), Elderly: Age Specific Diseases : CK(442) : AC(37)

Therapeutic Actions : Acupuncture : CK(1294) : AC(147)

Pharmacological Actions : Immunostimulatory : CK(143) : AC(33)

Astaxanthin addition improves human neutrophils function.

Click here to read the entire abstract

Pubmed Data : Eur J Nutr. 2010 Dec;49(8):447-57. Epub 2010 Apr 2. PMID: 20361333

Article Published Date : Dec 01, 2010

Study Type : Human Study

Additional Links

Substances : Astaxanthin : CK(353) : AC(117)

Diseases : Immune Disorders: Low Immune Function : CK(488) : AC(115), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Immunostimulatory : CK(143) : AC(33), Interleukin-6 Downregulation : CK(470) : AC(135), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)

Bloodroot and echinacea offset exercise-associated effects of immune activity.

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Pubmed Data : Blood Cells Mol Dis. 2009 Nov-Dec;43(3):298-303. Epub 2009 Sep 19. PMID: 19766513

Article Published Date : Nov 01, 2009

Study Type : Human Study

Additional Links

Substances : Bloodroot : CK(25) : AC(6), Echinacea : CK(469) : AC(88)

Diseases : Immune Disorders: Low Immune Function : CK(488) : AC(115), Low Immune Function: Exercise-Induced : CK(40) : AC(4)

Pharmacological Actions : Immunomodulatory : CK(536) : AC(142), Immunostimulatory : CK(143) : AC(33), Interleukin-1 beta downregulation : CK(177) : AC(70), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Breast-feeding is associated with a reduced frequency of acute otitis media and high serum antibody levels against Haemophilus influenzae.

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Pubmed Data : Pediatr Res. 2009 Nov;66(5):565-70. PMID: 19581824

Article Published Date : Nov 01, 2009

Study Type : Human Study

Additional Links

Substances : Breast Milk : CK(428) : AC(49)

Diseases : Childhood Infections : CK(275) : AC(29), Ear Infection : CK(604) : AC(33), Haemophilus influenzae : CK(54) : AC(9)

Therapeutic Actions : Breastfeeding : CK(708) : AC(67)

Pharmacological Actions : Immunostimulatory : CK(143) : AC(33)

Echinacea may attenuate the mucosal immune suppression known to occur with intense exercise and reduce the duration of upper respiratory tract infection that subjects incur.

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Pubmed Data : Int J Sports Med. 2007 Sep;28(9):792-7. Epub 2007 Apr 13. PMID: 17436202

Article Published Date : Sep 01, 2007

Study Type : Human Study

Additional Links

Substances : Echinacea : CK(469) : AC(88)

Diseases : Low Immune Function: Exercise-Induced : CK(40) : AC(4), Upper Respiratory Infections : CK(972) : AC(92)

Pharmacological Actions : Immunostimulatory : CK(143) : AC(33)

Oxihumante has immunstimulatory properties.

Click here to read the entire abstract

Pubmed Data : Z Naturforsch C. 2003 Mar-Apr;58(3-4):263-7. PMID: 12710739

Article Published Date : Mar 01, 2003

Study Type : Human Study

Additional Links

Substances : Humic Acid : CK(15) : AC(5)

Diseases : HIV Infections : CK(577) : AC(184), Immune Disorders: Low Immune Function : CK(488) : AC(115)

Pharmacological Actions : Immunostimulatory : CK(143) : AC(33), Interleukin-10 downregulation : CK(73) : AC(21), Interleukin-2 upregulation : CK(43) : AC(8)

Qigong practice may be protective against upper respiratory infections among elite swimmers who practice at least once per week.

Click here to read the entire abstract

Pubmed Data : Am J Chin Med. 2011 ;39(3):461-75. PMID: 21598415

Article Published Date : Jan 01, 2011

Study Type : Human Study

Additional Links

Diseases : Athletic Performance : CK(479) : AC(61), Cold and Flu : CK(1095) : AC(146), Common Cold : CK(473) : AC(56), Influenza : CK(654) : AC(102), Upper Respiratory Infections : CK(972) : AC(92)

Therapeutic Actions : Qigong : CK(216) : AC(25)

Pharmacological Actions : Immunostimulatory : CK(143) : AC(33)

Acupuncture exhibits age-delaying activity in mice.

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Pubmed Data : J Tradit Chin Med. 2009 Mar;29(1):54-9. PMID: 19514190

Article Published Date : Mar 01, 2009

Study Type : Animal Study

Additional Links

Diseases : Aging : CK(1351) : AC(369)

Therapeutic Actions : Acupuncture : CK(1294) : AC(147)

Pharmacological Actions : Immunostimulatory : CK(143) : AC(33)

Antrodia Camphorate extracts improve immune responses in mice with leukemia.

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Pubmed Data : Nutr Cancer. 2010 ;62(5):593-600. PMID: 20574920

Article Published Date : Jan 01, 2010

Study Type : Animal Study

Additional Links

Substances : Antrodia Camphorate : CK(2) : AC(1)

Diseases : Leukemia : CK(670) : AC(258), Low Immune Function: Natural Killer Cells : CK(108) : AC(21)

Pharmacological Actions : Immunostimulatory : CK(143) : AC(33)

Astaxanthin prevents chemically-induced fibrosarcoma cell proliferation.

Click here to read the entire abstract

Pubmed Data : Nutr Cancer. 2000;36(1):59-65. PMID: 10798217

Article Published Date : Jan 01, 2000

Study Type : Animal Study

Additional Links

Substances : Astaxanthin : CK(353) : AC(117)

Diseases : Fibrosarcoma : CK(10) : AC(7)

Pharmacological Actions : Chemopreventive : CK(1528) : AC(382), Immunostimulatory : CK(143) : AC(33), Interferon-gamma (IFN-gamma) inducer : CK(12) : AC(6)

Chlorella vulgaris restores bone marrow cellularity and cytokine production in lead-exposed mice.

Click here to read the entire abstract

Pubmed Data : Food Chem Toxicol. 2011 Jul 26. Epub 2011 Jul 26. PMID: 21820028

Article Published Date : Jul 26, 2011

Study Type : Animal Study

Additional Links

Substances : Chlorella (Algae) : CK(146) : AC(33)

Diseases : Bone Marrow Suppression : CK(14) : AC(4), Lead Poisoning : CK(173) : AC(34), Low Immune Function: Natural Killer Cells : CK(108) : AC(21)

Pharmacological Actions : Immunostimulatory : CK(143) : AC(33), Interleukin-1 alpha upregulation : CK(3) : AC(2), Tumor Necrosis Factor (TNF) Alpha Upregulation : CK(2) : AC(1)

Problem Substances : Lead : CK(97) : AC(15)

Adverse Pharmacological Actions : Immunotoxic : CK(230) : AC(38)

Curcumin acts as immunorestorer in tumor-bearing host.

Click here to read the entire abstract

Pubmed Data : Cancer Res. 2007 Jan 1;67(1):362-70. PMID: 17210719

Article Published Date : Jan 01, 2007

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482)

Diseases : Immune Disorders: Low Immune Function : CK(488) : AC(115), Oxidative Stress : CK(1945) : AC(710), Tumors : CK(197) : AC(110)

Pharmacological Actions : Apoptotic : CK(1489) : AC(1114), Immunostimulatory : CK(143) : AC(33), NF-kappaB Inhibitor : CK(595) : AC(401), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)

Curcumin has a immunomodulatory effect in host macrophages and NK cells which results in a tumoricidal effect.

Click here to read the entire abstract

Pubmed Data : FEBS Lett. 2000 Oct 13;483(1):78-82. PMID: 11033360

Article Published Date : Oct 13, 2000

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482)

Diseases : Low Immune Function: Natural Killer Cells : CK(108) : AC(21), Tumors : CK(197) : AC(110)

Pharmacological Actions : Antineoplastic Agents : CK(877) : AC(496), Antiproliferative : CK(1052) : AC(775), Immunomodulatory : CK(536) : AC(142), Immunostimulatory : CK(143) : AC(33)

Curcumin has variable immunomodulatory effects.

Click here to read the entire abstract

Pubmed Data : J Huazhong Univ Sci Technolog Med Sci. 2005;25(2):137-40. PMID: 16116955

Article Published Date : Jan 01, 2005

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482)

Pharmacological Actions : Immunomodulatory : CK(536) : AC(142), Immunostimulatory : CK(143) : AC(33), Immunosuppressive Agents : CK(26) : AC(19)

Curcumin's inhibition of intestinal tumors is associated with changes in the intestinal immune cell profile.

Click here to read the entire abstract

Pubmed Data : J Surg Res. 2000 Apr;89(2):169-75. PMID: 10729246

Article Published Date : Apr 01, 2000

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482)

Diseases : Immune Disorders: Low Immune Function : CK(488) : AC(115), Intestinal Cancer : CK(37) : AC(9), Intestinal Neoplasms : CK(2) : AC(1)

Pharmacological Actions : Antineoplastic Agents : CK(877) : AC(496), Immunomodulatory : CK(536) : AC(142), Immunostimulatory : CK(143) : AC(33)

Daily feeding of echinacea root enhances natural killer cells and increased survival of aging mice.

Click here to read the entire abstract

Pubmed Data : Biogerontology. 2005;6(3):157-63. PMID: 16041619

Article Published Date : Jan 01, 2005

Study Type : Animal Study

Additional Links

Substances : Echinacea : CK(469) : AC(88)

Diseases : Aging : CK(1351) : AC(369), Low Immune Function: Natural Killer Cells : CK(108) : AC(21)

Pharmacological Actions : Immunomodulatory : CK(536) : AC(142), Immunostimulatory : CK(143) : AC(33)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Dietary beta-carotene and astaxanthin but not canthaxanthin stimulate splenocyte function in mice.

Click here to read the entire abstract

Pubmed Data : Anticancer Res. 1999 Nov-Dec;19(6B):5223-7. PMID: 10697539

Article Published Date : Nov 01, 1999

Study Type : Animal Study

Additional Links

Substances : Astaxanthin : CK(353) : AC(117), beta-Carotene : CK(217) : AC(38)

Diseases : Low Immune Function: Splenic Dysfunction : CK(13) : AC(7)

Pharmacological Actions : Immunostimulatory : CK(143) : AC(33)

Dietary L-arginine supplementation alleviates immunosuppression induced by cyclophosphamide in weaned pigs.

Click here to read the entire abstract

Pubmed Data : Amino Acids. 2009 Oct;37(4):643-51. Epub 2008 Sep 28. PMID: 18821052

Article Published Date : Oct 01, 2009

Study Type : Animal Study

Additional Links

Substances : Arginine : CK(970) : AC(169)

Diseases : Chemotherapy-Induced Toxicity: Cyclophosphamide : CK(27) : AC(10)

Pharmacological Actions : Immunostimulatory : CK(143) : AC(33)

Dietary L-arginine supplementation enhances the immune status in early-weaned piglets.

Click here to read the entire abstract

Pubmed Data : Amino Acids. 2009 Jul;37(2):323-31. Epub 2008 Aug 19. PMID: 18712273

Article Published Date : Jul 01, 2009

Study Type : Animal Study

Additional Links

Substances : Arginine : CK(970) : AC(169)

Diseases : Immune Disorders: Low Immune Function : CK(488) : AC(115)

Pharmacological Actions : Immunostimulatory : CK(143) : AC(33)

Echinacea exhibits antioxidant and immune-enhancing properties.

Click here to read the entire abstract

Pubmed Data : Biol Pharm Bull. 2004 Jul;27(7):1004-9. PMID: 15256730

Article Published Date : Jul 01, 2004

Study Type : Animal Study

Additional Links

Substances : Echinacea : CK(469) : AC(88)

Diseases : Immune Disorders: Low Immune Function : CK(488) : AC(115), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Immunomodulatory : CK(536) : AC(142), Immunostimulatory : CK(143) : AC(33)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Echinacea has a prophylactic role against infection through supporting nonspecific immunity.

Click here to read the entire abstract

Pubmed Data : J Altern Complement Med. 1999 Oct;5(5):437-46. PMID: 10537243

Article Published Date : Oct 01, 1999

Study Type : Animal Study

Additional Links

Substances : Echinacea : CK(469) : AC(88)

Diseases : Immune Disorders: Low Immune Function : CK(488) : AC(115)

Pharmacological Actions : Immunomodulatory : CK(536) : AC(142), Immunostimulatory : CK(143) : AC(33)

Echinacea is a potent activator of natural killer cell cytotoxicity.

Click here to read the entire abstract

Pubmed Data : Int Immunopharmacol. 2003 Jun;3(6):811-24. PMID: 12781698

Article Published Date : Jun 01, 2003

Study Type : Animal Study

Additional Links

Substances : Echinacea : CK(469) : AC(88)

Diseases : Low Immune Function: Natural Killer Cells : CK(108) : AC(21)

Pharmacological Actions : Immunostimulatory : CK(143) : AC(33)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Echinacea is capable of enhancing the humoral immune response.

Click here to read the entire abstract

Pubmed Data : Am J Gastroenterol. 2008 Sep;103(9):2308-13. Epub 2008 Aug 12. PMID: 14686797

Article Published Date : Sep 01, 2008

Study Type : Animal Study

Additional Links

Substances : Echinacea : CK(469) : AC(88)

Diseases : Immune Disorders: Low Immune Function : CK(488) : AC(115), Low Immune Function: TH2 deficient : CK(2) : AC(1)

Pharmacological Actions : Immunostimulatory : CK(143) : AC(33)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

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