Secretagogue

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Quick Summary: Current access displays 2 out of 44 associated Substances
NameCumulative KnowledgeArticle CountFocus Articles
Melatonin223Log in | Sign up
GABA (gamma-Aminobutyric Acid)202Log in | Sign up
View the Evidence: Pharmacological Actions

Arginine and ornithine supplementation increases growth hormone and insulin-like growth factor-1 serum levels after heavy-resistance exercise in strength-trained athletes.

Pubmed Data : J Strength Cond Res. 2010 Apr;24(4):1082-90. PMID: 20300016
Article Published Date : Apr 01, 2010
Study Type : Human Study
Additional Links
Substances : Arginine : CK(970) : AC(169)
Diseases : Athletic Performance : CK(489) : AC(63), Insulin-Like Growth Factor (IGF): Low : CK(20) : AC(2), Low Human Growth Hormone : CK(33) : AC(6)
Pharmacological Actions : Secretagogue : CK(158) : AC(36)
Additional Keywords : Strength Training : CK(10) : AC(1)

GABA significantly increases indicators of Human Growth Hormone production in human subjects. - Article 2

Pubmed Data : Acta Endocrinol (Copenh). 1980 Feb;93(2):149-54. PMID: 7376786
Article Published Date : Feb 01, 1980
Study Type : Human Study
Additional Links
Substances : GABA (gamma-Aminobutyric Acid) : CK(37) : AC(8)
Diseases : Human Growth Hormone: Enhancement : CK(74) : AC(10)
Pharmacological Actions : Secretagogue : CK(158) : AC(36)

GABA significantly increases indicators of Human Growth Hormone production in human subjects.- Article 1

Pubmed Data : Med Sci Sports Exerc. 2008 Jan;40(1):104-10. PMID: 18091016
Article Published Date : Jan 01, 2008
Study Type : Human Study
Additional Links
Substances : GABA (gamma-Aminobutyric Acid) : CK(37) : AC(8)
Diseases : Human Growth Hormone: Enhancement : CK(74) : AC(10)
Pharmacological Actions : Secretagogue : CK(158) : AC(36)

High intake of fat is associated with higher serum levels of estrone and DHEAS in postmenopausal women.

Pubmed Data : J Nutr. 2005 Dec;135(12):2862-5. PMID: 16317133
Article Published Date : Dec 01, 2005
Study Type : Human Study
Additional Links
Substances : Fat: All : CK(1685) : AC(225)
Diseases : DHEA: Low : CK(38) : AC(8), Estrogen Deficiency : CK(64) : AC(19), Estrone: Too Low : CK(10) : AC(1), Hormone Insufficency : CK(29) : AC(7), Postmenopausal Disorders : CK(285) : AC(35)
Pharmacological Actions : Secretagogue : CK(158) : AC(36)

Intake of fermented soybean (natto) increases circulating vitamin K2 and osteocalcin (a marker for bone formation) in normal individuals.

Pubmed Data : J Bone Miner Metab. 2000;18(4):216-22. PMID: 10874601
Article Published Date : Jan 01, 2000
Study Type : Human Study
Additional Links
Substances : Natto : CK(121) : AC(21), Vitamin K : CK(549) : AC(63)
Diseases : Osteoporosis : CK(1090) : AC(205)
Pharmacological Actions : Secretagogue : CK(158) : AC(36)

Magnesium levels are strongly and independently associated with the anabolic hormones testosterone and IGF-1.

Pubmed Data : Clin Exp Rheumatol. 2002 Nov-Dec;20(6):767-71. PMID: 21675994
Article Published Date : Nov 01, 2002
Study Type : Human Study
Additional Links
Substances : Magnesium : CK(827) : AC(116)
Diseases : Insulin-Like Growth Factor (IGF): Low : CK(20) : AC(2), Testosterone: Too Low : CK(385) : AC(74)
Pharmacological Actions : Anabolic Agents : CK(42) : AC(10), Secretagogue : CK(158) : AC(36)

Meditation results in acute increases in night-time plasma melatonin levels.

Pubmed Data : Biol Psychol. 2000 May;53(1):69-78. PMID: 10876066
Article Published Date : May 01, 2000
Study Type : Human Study
Additional Links
Substances : Melatonin : CK(464) : AC(117)
Diseases : Hormone Imbalances: Low Melatonin : CK(64) : AC(7)
Pharmacological Actions : Secretagogue : CK(158) : AC(36)

Progesterone prevents sleep disturbances and modulates GH, TSH, and melatonin secretion in postmenopausal women.

Pubmed Data : J Clin Endocrinol Metab. 2011 Feb 2. Epub 2011 Feb 2. PMID: 21289261
Article Published Date : Feb 02, 2011
Study Type : Human Study
Additional Links
Substances : Progesterone : CK(72) : AC(24)
Diseases : Human Growth Hormone: Enhancement : CK(74) : AC(10), Inappropriate Growth Hormone Secretion Syndrome : CK(11) : AC(1), Inappropriate TSH Secretion Syndrome : CK(20) : AC(2), Low Human Growth Hormone : CK(33) : AC(6), Postmenopausal Disorders : CK(285) : AC(35), TSH: Elevated : CK(20) : AC(2)
Pharmacological Actions : Secretagogue : CK(158) : AC(36)

Transcranial magnetotherapy (TcMT) and electric stimulation (ES) improve erectile dysfunction in obese patients.

Pubmed Data : Vopr Kurortol Fizioter Lech Fiz Kult. 2009 Sep-Oct(5):30-3. PMID: 19886019
Article Published Date : Sep 01, 2009
Study Type : Human Study
Additional Links
Diseases : Erectile Dysfunction : CK(510) : AC(41), Low Testosterone : CK(385) : AC(70)
Therapeutic Actions : Electric Stimulation : CK(31) : AC(4), Magnet Therapy : CK(44) : AC(6)
Pharmacological Actions : Secretagogue : CK(158) : AC(36)

Vitamin A supplementation increases progesterone levels during pregnancy.

Pubmed Data : Int J Vitam Nutr Res. 1991;61(1):17-9. PMID: 1856040
Article Published Date : Jan 01, 1991
Study Type : Human Study
Additional Links
Substances : Vitamin A : CK(371) : AC(58)
Diseases : Progesterone: Low : CK(34) : AC(15)
Pharmacological Actions : Secretagogue : CK(158) : AC(36)

Warming up breasts by a breast compress is easy and affordable, and this procedure increases the amount of breastmilk.

Pubmed Data : Breastfeed Med. 2012 Mar 16. Epub 2012 Mar 16. PMID: 22424466
Article Published Date : Mar 16, 2012
Study Type : Human Study
Additional Links
Diseases : Breast Milk: Inadequate/Poor Quality : CK(60) : AC(7), Lactation Disorders : CK(132) : AC(16)
Therapeutic Actions : Warming Compresses : CK(10) : AC(1)
Pharmacological Actions : Galactogogue : CK(13) : AC(3), Secretagogue : CK(158) : AC(36)

Yogic practices can be used as psychophysiologic stimuli to increase endogenous secretion of melatonin, which, in turn, might be responsible for improved sense of well-being.

Pubmed Data : J Altern Complement Med. 2004 Apr;10(2):261-8. PMID: 15165407
Article Published Date : Apr 01, 2004
Study Type : Human Study
Additional Links
Substances : Melatonin : CK(464) : AC(117)
Pharmacological Actions : Secretagogue : CK(158) : AC(36)

A mixture of asian herbs increases progesterone secretion in female rats.

Pubmed Data : Am J Chin Med. 1991;19(1):57-60. PMID: 1897491
Article Published Date : Jan 01, 1991
Study Type : Animal Study
Additional Links
Substances : Angelica : CK(67) : AC(25), Cnidium : CK(14) : AC(3), Peony : CK(54) : AC(12), Poria cocos : CK(4) : AC(3)
Diseases : Progesterone: Low : CK(34) : AC(15)
Pharmacological Actions : Secretagogue : CK(158) : AC(36)

Arginine supplementation increases progesterone levels in female sheep.

Pubmed Data : Pak J Biol Sci. 2008 Oct 15;11(20):2389-94. PMID: 19137847
Article Published Date : Oct 15, 2008
Study Type : Animal Study
Additional Links
Substances : Arginine : CK(970) : AC(169)
Diseases : Progesterone: Low : CK(34) : AC(15)
Pharmacological Actions : Secretagogue : CK(158) : AC(36)

Brown kelp exhibits anti-estrogenic activity and mildly increases progesterone levels in female rats.

Pubmed Data : J Nutr. 2005 Feb;135(2):296-300. PMID: 15671230
Article Published Date : Feb 01, 2005
Study Type : Animal Study
Additional Links
Substances : Seaweed: Brown : CK(49) : AC(5)
Diseases : Estrogen Dominance : CK(107) : AC(38), Progesterone: Low : CK(34) : AC(15)
Pharmacological Actions : Secretagogue : CK(158) : AC(36)
Additional Keywords : Hormone Dependent Cancers : CK(2) : AC(1)

Cholesterol stimulates progesterone production in cows, regardless of the lipoprotein type from which it is sourced.

Pubmed Data : Biochim Biophys Acta. 2010 Feb 23. Epub 2010 Feb 23. PMID: 1401371
Article Published Date : Feb 23, 2010
Study Type : Animal Study
Additional Links
Substances : Cholesterol : CK(392) : AC(43)
Diseases : Progesterone: Low : CK(34) : AC(15)
Pharmacological Actions : Secretagogue : CK(158) : AC(36)

Fenugreek seeds increase rat growth hormone from rat pituitary cells.

Pubmed Data : J Food Sci. 2007 Jan;72(1):S055-8. PMID: 18816528
Article Published Date : Jan 01, 2007
Study Type : Animal Study
Additional Links
Substances : Fenugreek : CK(71) : AC(28)
Diseases : Human Growth Hormone: Enhancement : CK(74) : AC(10)
Pharmacological Actions : Secretagogue : CK(158) : AC(36)
Additional Keywords : Human Growth Hormone : CK(2) : AC(1)

Ginsenoside Rg1, a compound found within ginseng, improves male copulatory behavior in mice.

Pubmed Data : J Sex Med. 2009 Sep 14. Epub 2009 Sep 14. PMID: 19751391
Article Published Date : Sep 14, 2009
Study Type : Animal Study
Additional Links
Substances : Ginsenosides : CK(48) : AC(19)
Diseases : Erectile Dysfunction : CK(510) : AC(41), Low Libido : CK(73) : AC(21), Low Testosterone : CK(385) : AC(70)
Pharmacological Actions : Aphrodisiac : CK(49) : AC(17), Nitric Oxide Enhancer : CK(137) : AC(35), Secretagogue : CK(158) : AC(36)

Panax ginseng contains a compound, ginsenoside-Rb1, which increases the secretion of luteinizing hormone in male rats.

Pubmed Data : Chin J Physiol. 2003 Mar 31;46(1):1-7. PMID: 12817698
Article Published Date : Mar 31, 2003
Study Type : Animal Study
Additional Links
Substances : Panax Ginseng : CK(49) : AC(21)
Diseases : Inappropriate Luteinizing Hormone Secretion : CK(2) : AC(1)
Pharmacological Actions : Secretagogue : CK(158) : AC(36)

Panthothenic acid stimulates the adrenal cells in male rats to secrete corticosterone and progesterone.

Pubmed Data : Biol Pharm Bull. 2008 Jun;31(6):1205-8. PMID: 18520055
Article Published Date : Jun 01, 2008
Study Type : Animal Study
Additional Links
Substances : Pantothenic Acid (Vitamin B-5) : CK(52) : AC(9)
Diseases : Adrenal Insufficiency : CK(155) : AC(18), Progesterone: Low : CK(34) : AC(15)
Pharmacological Actions : Secretagogue : CK(158) : AC(36)

Pantothenic acid improves testosterone, corticosterone and testicular function in male rats.

Pubmed Data : J Vet Med Sci. 2009 Nov;71(11):1427-32. PMID: 19959891
Article Published Date : Nov 01, 2009
Study Type : Animal Study
Additional Links
Substances : Pantothenic Acid (Vitamin B-5) : CK(52) : AC(9)
Diseases : Corticosterone Deficiency : CK(45) : AC(1), Infertility: Male : CK(201) : AC(53), Low Testosterone : CK(385) : AC(70), Sperm Quality: Low : CK(150) : AC(28), Testicular Diseases : CK(38) : AC(15)
Pharmacological Actions : Secretagogue : CK(158) : AC(36)

Phytoestrogens can stimulate testosterone synthesis during puberty in male goats by increasing the secretion of T3; a hormone known to stimulate Leydig cell steroidogenesis.

Pubmed Data : Acta Vet Scand. 2009 Dec 10;51:51. PMID: 20003293
Article Published Date : Dec 10, 2009
Study Type : Animal Study
Additional Links
Substances : Biochanin A : CK(9) : AC(8), Daidzein : CK(983) : AC(28), Formononetin : CK(2) : AC(1), Genistein : CK(436) : AC(174), phytoestrogens : CK(149) : AC(29)
Diseases : Hypothyroidism : CK(516) : AC(78), Low Testosterone : CK(385) : AC(70)
Pharmacological Actions : Secretagogue : CK(158) : AC(36), Steroidogenesis : CK(3) : AC(2)

Silymarin, a compound found within milk thistle, induces hyperprolactinemia in female rats.

Pubmed Data : Phytomedicine. 2009 Sep;16(9):839-44. Epub 2009 Mar 20. PMID: 19303749
Article Published Date : Sep 01, 2009
Study Type : Animal Study
Additional Links
Substances : Milk Thistle : CK(226) : AC(55)
Diseases : Lactation Disorders : CK(132) : AC(16)
Pharmacological Actions : Secretagogue : CK(158) : AC(36)

Suma appears to raise levels of sex hormones, as evidenced in mice.

Pubmed Data : J Reprod Dev. 2003 Apr;49(2):175-80. PMID: 14967943
Article Published Date : Apr 01, 2003
Study Type : Animal Study
Additional Links
Substances : Suma (Pfaffia Paniculata) : CK(8) : AC(5)
Diseases : Hormone Insufficency : CK(29) : AC(7), Hormones: Insufficient Levels : CK(342) : AC(74), Low Testosterone : CK(385) : AC(70)
Pharmacological Actions : Secretagogue : CK(158) : AC(36)

Tongkat Ali (Euycoma longifolia) improved sexual performance and testosterone but not motivation in sluggish rats.

Pubmed Data : J Ethnopharmacol. 2009 Nov 12;126(2):308-13. Epub 2009 Aug 22. PMID: 19703544
Article Published Date : Nov 12, 2009
Study Type : Animal Study
Additional Links
Substances : Tongkat Ali : CK(7) : AC(5)
Diseases : Erectile Dysfunction : CK(510) : AC(41), Low Testosterone : CK(385) : AC(70), Sexual Dysfunction : CK(74) : AC(13)
Pharmacological Actions : Secretagogue : CK(158) : AC(36)

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