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Additional Topics Details for this Page
Article Count
- 6
Cumulative Knowledge
- 9
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Quick Summary: 2 associated Substances
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Resveratrol
9
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View the Evidence: Pharmacological Actions
Caloric restriction and resveratrol promote longevity.
Click here to read the entire abstract
Pubmed Data
: Cell Death Dis. 2010 Jan;1(1):e10. PMID:
21364612
Article Published Date
: Jan 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Resveratrol : CK(977) : AC(590)
Diseases
:
Aging : CK(1351) : AC(369)
Therapeutic Actions
:
Fasting/Caloric Restriction : CK(235) : AC(50)
Pharmacological Actions
:
Autophagy Up-regulation : CK(18) : AC(13)
,
SIRT1 Activator : CK(9) : AC(6)
Resveratrol may protect against colitis through up-regulation of SIRT1 in immune cells in the colon.
Click here to read the entire abstract
Pubmed Data
: J Pharmacol Exp Ther. 2010 Mar;332(3):829-39. Epub 2009 Nov 25. PMID:
19940103
Article Published Date
: Mar 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Resveratrol : CK(977) : AC(590)
,
Stilbenes : CK(128) : AC(92)
Diseases
:
Colitis : CK(368) : AC(53)
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors : CK(269) : AC(169)
,
NF-kappaB Inhibitor : CK(595) : AC(401)
,
SIRT1 Activator : CK(9) : AC(6)
Resveratrol, an activator of SIRT1, upregulates sarcoplasmic calcium ATPase and improves cardiac function in diabetic cardiomyopathy.
Click here to read the entire abstract
Pubmed Data
: Am J Physiol Heart Circ Physiol. 2010 Mar;298(3):H833-43. Epub 2009 Dec 11. PMID:
20008278
Article Published Date
: Mar 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Resveratrol : CK(977) : AC(590)
,
Stilbenes : CK(128) : AC(92)
Diseases
:
Cardiomyopathy : CK(77) : AC(15)
,
Diabetes: Cardiovascular Illness : CK(666) : AC(104)
Pharmacological Actions
:
Antioxidants : CK(3653) : AC(1318)
,
Sarcoplasmic Calcium ATPase Up-regulation : CK(2) : AC(1)
,
SIRT1 Activator : CK(9) : AC(6)
Resveratrol displays pro-survival and pro-hypertrophic properties via activation of the longevity associated SIRT1 gene in cardiomyocytes.
Click here to read the entire abstract
Pubmed Data
: Cancer Lett. 2005 Aug 26;226(2):107-13. Epub 2004 Dec 28. PMID:
21276800
Article Published Date
: Aug 26, 2005
Study Type
: In Vitro Study
Additional Links
Substances
:
Resveratrol : CK(977) : AC(590)
Diseases
:
Cardiovascular Diseases : CK(5138) : AC(641)
Pharmacological Actions
:
SIRT1 Activator : CK(9) : AC(6)
Resveratrol inhibits high glucose-induced cellular aging in endothelial cells.
Click here to read the entire abstract
Pubmed Data
: Clin Exp Pharmacol Physiol. 2010 May;37(5-6):630-5. Epub 2010 Feb 4. PMID:
20132235
Article Published Date
: May 01, 2010
Study Type
: In Vitro Study
Additional Links
Substances
:
Resveratrol : CK(977) : AC(590)
Diseases
:
Aging : CK(1351) : AC(369)
,
Endothelial Dysfunction : CK(897) : AC(173)
,
Hyperglycemia : CK(2892) : AC(59)
Pharmacological Actions
:
Antioxidants : CK(3653) : AC(1318)
,
Nitric Oxide Inhibitor : CK(108) : AC(57)
,
SIRT1 Activator : CK(9) : AC(6)
Additional Keywords
:
Stilbenes : CK(402) : AC(242)
Review: resveratrol as a therapeutic agent for neurodegenerative diseases.
Click here to read the entire abstract
Pubmed Data
: Mol Neurobiol. 2010 Jun;41(2-3):375-83. Epub 2010 Mar 21. PMID:
20306310
Article Published Date
: Jun 01, 2010
Study Type
: Review
Additional Links
Substances
:
Resveratrol : CK(977) : AC(590)
,
Stilbenes : CK(128) : AC(92)
Diseases
:
Alzheimer's Disease : CK(826) : AC(160)
,
Inflammation : CK(1077) : AC(363)
,
Neurodegenerative Diseases : CK(1743) : AC(420)
,
Oxidative Stress : CK(1945) : AC(710)
,
Parkinson Disease : CK(543) : AC(79)
Pharmacological Actions
:
Antioxidants : CK(3653) : AC(1318)
,
Apoptotic : CK(1489) : AC(1114)
,
SIRT1 Activator : CK(9) : AC(6)
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