Telomerase Upregulation

User Options

A Membership is required. Please Login or Create an account to get started

Purchase the Exhaustive Downloadable Document on this Topic

Make a Request for GMI to add more Articles on this Topic Immediately (Purchase Required)

View a Printer Friendly version of this page

E-mail this page to a friend

Perform a Search with this Topic

Hover over an icon for more information

Additional Topics Details for this Page

Article Count - 27
Cumulative Knowledge - 101

Advanced Database Options

Limit Articles Displayed by the Following Study Types

Available Sorting Options

Limited to Members Only

By default, all articles on GreenMedInfo.com are sorted based on the content type which best reflects the data which most users are searching for. For instance, people viewing substances are generally most interested in viewing diseases that these substances have shown to have positive influences. This section is for allowing more advanced sorting methods. Currently, these advanced sorting methods are available for members only. If you are already a member, you can sign in by clicking here. If you do not currently have a user account, and would like to create one/become a member, click here to begin the singup process.

Currently Available Sorting Options

Article Published Date - Sort all displayed articles by their published date
Quick Summary Fieldsets - Sort alphabetically, rather than by Cumulative Knowledge
Cumulative Knowledge - Default sorting method. Allows you to sort descendingly

What is Cumulative Knowledge?

Cumulative Knowledge is determined by ascribing a numerical value to the various study types weighted in descending order as follows: (1) Meta-Analysis; (2) Human Study; (3) Human: Case Study; (4) Animal: Transgenic; (5) Animal; (6) In Vitro; (7) Review; and (8) Commentary.

Click here for a more thorough explanation.

Quick Summary: Current access displays 2 out of 20 associated Substances

Name	Cumulative Knowledge	Article Count	Focus Articles
Vitamin E	31	3	Log in \| Sign up
Cynanchum Auriculatum	20	1	Log in \| Sign up

Currently Viewing Free Sample of Member Only Features

Although all 20,000+ articles on GreenMedInfo.com are made entirely free to view as an educational service to the public, we provide a powerful set of enhanced data comprehension and retrieval tools for subscribing members. Above you are viewing a free preview, limited to 2 rows, of the membership feature called "Cumulative Knowledge" (learn more).

The Focus Article Feature is not enabled.

Upgrading to the Friend membership gives you access to unlimited rows of Cumulative Knowledge data.

To Participate

Click here to login
Click here to create an account

View the Evidence: Pharmacological Actions

Cynanchum auriculatum in combination with vitamin E exhibits anti-aging properties.

Click here to read the entire abstract

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2007 Dec;32(23):2511-4. PMID: 18330246

Article Published Date : Dec 01, 2007

Study Type : Meta Analysis

Additional Links

Substances : Cynanchum Auriculatum : CK(20) : AC(1), Vitamin E : CK(1417) : AC(250)

Diseases : Aging : CK(1399) : AC(392)

Pharmacological Actions : Malondialdehyde Down-regulation : CK(238) : AC(60), Superoxide Dismutase Up-regulation : CK(159) : AC(53), Telomerase Upregulation : CK(101) : AC(27)

Comprehensive lifestyle changes significantly increase telomerase activity and consequently telomere maintenance capacity in human immune-system cells.

Click here to read the entire abstract

Pubmed Data : Lancet Oncol. 2008 Nov;9(11):1048-57. Epub 2008 Sep 15. PMID: 18799354

Article Published Date : Nov 01, 2008

Study Type : Human Study

Additional Links

Diseases : Aging : CK(1399) : AC(392)

Therapeutic Actions : Lifestyle Changes: Positive : CK(10) : AC(1)

Pharmacological Actions : Telomerase Upregulation : CK(101) : AC(27)

Long-term endurance exercise training may provide a protective effect on muscle telomere length in older people.

Click here to read the entire abstract

Pubmed Data : PLoS One. 2012 ;7(12):e52769. Epub 2012 Dec 26. PMID: 23300766

Article Published Date : Dec 31, 2011

Study Type : Human Study

Additional Links

Diseases : Aging : CK(1399) : AC(392)

Therapeutic Actions : Exercise: Endurance : CK(10) : AC(1)

Pharmacological Actions : Telomerase Upregulation : CK(101) : AC(27), Telomere Protective : CK(21) : AC(3)

Loving-Kindness Meditation practice associated with longer telomeres in women.

Click here to read the entire abstract

Pubmed Data : Brain Behav Immun. 2013 Apr 19. Epub 2013 Apr 19. PMID: 23602876

Article Published Date : Apr 18, 2013

Study Type : Human Study

Additional Links

Diseases : Aging : CK(1399) : AC(392)

Therapeutic Actions : Kindness : CK(20) : AC(2), Meditation : CK(121) : AC(13)

Pharmacological Actions : Telomerase Upregulation : CK(101) : AC(27), Telomere Protective : CK(21) : AC(3)

Meditation is associated with increased telomerase activity associated with cell longevity.

Click here to read the entire abstract

Pubmed Data : Psychoneuroendocrinology. 2010 Oct 29. Epub 2010 Oct 29. PMID: 21035949

Article Published Date : Oct 29, 2010

Study Type : Human Study

Additional Links

Diseases : Aging : CK(1399) : AC(392)

Therapeutic Actions : Meditation : CK(121) : AC(13)

Pharmacological Actions : Telomerase Upregulation : CK(101) : AC(27)

Multivitamin use is associated with longer telomere length in women.

Click here to read the entire abstract

Pubmed Data : Hepatogastroenterology. 2002 Nov-Dec;49(48):1571-5. PMID: 19279081

Article Published Date : Nov 01, 2002

Study Type : Human Study

Additional Links

Substances : Multivitamin : CK(244) : AC(22), Vitamin C : CK(1538) : AC(271), Vitamin E : CK(1417) : AC(250)

Diseases : Aging : CK(1399) : AC(392)

Pharmacological Actions : Telomerase Upregulation : CK(101) : AC(27)

"Vitamin D may improve telomere maintenance and prevent cell senescence and counteract obesity-induced acceleration of cellular aging."

Click here to read the entire abstract

Pubmed Data : Int J Obes (Lond). 2012 Jun ;36(6):805-9. Epub 2011 Oct 11. PMID: 21986705

Article Published Date : Jun 01, 2012

Study Type : Human In Vitro

Additional Links

Substances : Vitamin D : CK(1760) : AC(247)

Diseases : African-American Specific Deficiencies/Diseases : CK(205) : AC(20), Aging : CK(1399) : AC(392), Obesity : CK(2013) : AC(288)

Pharmacological Actions : Telomerase Upregulation : CK(101) : AC(27)

An aqueous extract of purslane has anti-anging activity.

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2009 Apr 15. PMID: 19367671

Article Published Date : Apr 15, 2009

Study Type : Animal Study

Additional Links

Substances : Purslane : CK(48) : AC(15)

Diseases : Aging : CK(1399) : AC(392)

Pharmacological Actions : Telomerase Upregulation : CK(101) : AC(27)

Additional Keywords : Upregulation of Telemere Length : CK(4) : AC(3)

Cynomorium songaricum polysaccharide may exert an anti-aging effect by increase telomere length of aged mice.

Click here to read the entire abstract

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2009 May;34(10):1257-60. PMID: 19673390

Article Published Date : May 01, 2009

Study Type : Animal Study

Additional Links

Substances : Cynomorium songaricum : CK(5) : AC(3)

Diseases : Aging : CK(1399) : AC(392)

Pharmacological Actions : Telomerase Upregulation : CK(101) : AC(27)

Physical exercise increases adult neurogenesis and telomerase activity, and improves behavioral deficits in a mouse model of schizophrenia.

Click here to read the entire abstract

Pubmed Data : Brain Behav Immun. 2011 Jul;25(5):971-80. Epub 2010 Oct 21. PMID: 20970493

Article Published Date : Jul 01, 2011

Study Type : Animal Study

Additional Links

Diseases : Schizophrenia : CK(311) : AC(32)

Therapeutic Actions : Exercise : CK(553) : AC(77)

Pharmacological Actions : Neuritogenic : CK(125) : AC(51), Telomerase Upregulation : CK(101) : AC(27)

Sijunzi decoction exhibits anti-aging properties, including increases in telomerase activity.

Click here to read the entire abstract

Pubmed Data : Biosci Biotechnol Biochem. 2006 May;70(5):1118-26. PMID: 16025969

Article Published Date : May 01, 2006

Study Type : Animal Study

Additional Links

Substances : Traditional Chinese Medicine: Sijunzi Decoction : CK(2) : AC(1)

Diseases : Aging : CK(1399) : AC(392)

Pharmacological Actions : Antioxidants : CK(5301) : AC(1618), Telomerase Upregulation : CK(101) : AC(27)

TA-65 dietary supplementation in female mice leads to an improvement of certain health-span indicators including glucose tolerance, osteoporosis and skin fitness, without significantly increasing global cancer incidence.

Click here to read the entire abstract

Pubmed Data : Aging Cell. 2011 Aug ;10(4):604-21. Epub 2011 Apr 14. PMID: 21426483

Article Published Date : Jul 31, 2011

Study Type : Animal Study

Additional Links

Substances : TA-65 (Astragalus compound) : CK(2) : AC(1)

Diseases : Aging : CK(1399) : AC(392), DNA damage : CK(728) : AC(304), Osteoporosis : CK(1198) : AC(221)

Pharmacological Actions : Anticarcinogenic Agents : CK(756) : AC(282), Telomerase Upregulation : CK(101) : AC(27)

Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice.

Click here to read the entire abstract

Pubmed Data : Nature. 2011 Jan 6;469(7328):102-6. Epub 2010 Nov 28. PMID: 21113150

Article Published Date : Jan 06, 2011

Study Type : Animal Study

Additional Links

Diseases : Aging : CK(1399) : AC(392)

Pharmacological Actions : Antiproliferative : CK(1752) : AC(1193), Telomerase Upregulation : CK(101) : AC(27)

Additional Keywords : Drug: Tamoxifen : CK(380) : AC(57)

A compound found within astragalus called cycloastragenol may enhance immune function by retarding telomere loss in white blood cells associated with chronic viral infection.

Click here to read the entire abstract

Pubmed Data : J Immunol. 2008 Nov 15;181(10):7400-6. PMID: 18981163

Article Published Date : Nov 15, 2008

Study Type : In Vitro Study

Additional Links

Substances : Astragalus : CK(225) : AC(51), Cycloastragenol : CK(1) : AC(1)

Diseases : HIV Infections : CK(609) : AC(186)

Pharmacological Actions : Enzyme Inhibitors : CK(417) : AC(225), Immunomodulatory : CK(771) : AC(201), Telomerase Upregulation : CK(101) : AC(27)

Additional Keywords : Upregulation of Telemere Length : CK(4) : AC(3)

Alpha-tocopherol prevents hydrogen peroxide-induced DNA damage and telomere shortening and upregulates telomerase activity in human skin cells.

Click here to read the entire abstract

Pubmed Data : Planta Med. 2010 Jun;76(9):869-75. Epub 2010 Jan 28. PMID: 20112180

Article Published Date : Jun 01, 2010

Study Type : In Vitro Study

Additional Links

Substances : Vitamin E : CK(1417) : AC(250)

Diseases : Aging : CK(1399) : AC(392), Aging Skin : CK(387) : AC(93), DNA damage : CK(728) : AC(304), Oxidative Stress : CK(2855) : AC(750)

Pharmacological Actions : Telomerase Upregulation : CK(101) : AC(27)

Astragalus contains compounds which slow cell aging through reduced telomere shortening rate, oxidative stress and increasing DNA repair ability.

Click here to read the entire abstract

Pubmed Data : DNA Cell Biol. 2010 Jan;29(1):33-9. PMID: 19839736

Article Published Date : Jan 01, 2010

Study Type : In Vitro Study

Additional Links

Substances : Astragalus : CK(225) : AC(51), HDTIC-1 : CK(3) : AC(3), HDTIC-2 : CK(3) : AC(3)

Diseases : Aging : CK(1399) : AC(392), DNA damage : CK(728) : AC(304), Oxidative Stress : CK(2855) : AC(750)

Pharmacological Actions : Telomerase Upregulation : CK(101) : AC(27)

Chlorella exhibits bioprotective properties against experimentally induced DNA damage and telomerase inhibition.

Click here to read the entire abstract

Pubmed Data : Afr J Tradit Complement Altern Med. 2009;6(4):560-72. Epub 2009 Jul 3. PMID: 20606778

Article Published Date : Jan 01, 2009

Study Type : In Vitro Study

Additional Links

Substances : Chlorella (Algae) : CK(146) : AC(34)

Diseases : Aging : CK(1399) : AC(392), DNA damage : CK(728) : AC(304), Oxidative Stress : CK(2855) : AC(750)

Pharmacological Actions : Genoprotective : CK(119) : AC(50), Telomerase Upregulation : CK(101) : AC(27)

Estrogen reduces endothelial progenitor cell senescence through augmentation of telomerase activity.

Click here to read the entire abstract

Pubmed Data : J Hypertens. 2005 Sep;23(9):1699-706. PMID: 16093915

Article Published Date : Sep 01, 2005

Study Type : In Vitro Study

Additional Links

Substances : Estradiol (E(2)) : CK(21) : AC(14)

Diseases : Aging : CK(1399) : AC(392), Endothelial Dysfunction : CK(1079) : AC(181)

Pharmacological Actions : Antiproliferative : CK(1752) : AC(1193), Enzyme Inhibitors : CK(417) : AC(225), Telomerase Upregulation : CK(101) : AC(27), Vascular Endothelial Growth Factor A Inhibitor : CK(112) : AC(63)

Estrogen reduces endothelial progenitor cell senescence through augmentation of telomerase activity.

Click here to read the entire abstract

Pubmed Data : Ther Adv Cardiovasc Dis. 2010 Feb;4(1):55-69. Epub 2009 Dec 4. PMID: 19965898

Article Published Date : Feb 01, 2010

Study Type : Review

Additional Links

Substances : Estradiol (E(2)) : CK(21) : AC(14)

Diseases : Aging : CK(1399) : AC(392), Endothelial Dysfunction : CK(1079) : AC(181)

Pharmacological Actions : Telomerase Upregulation : CK(101) : AC(27)

Gamma-tocotrienol protects against oxidative stress-induced cellular ageing by modulating the telomere length possibly via telomerase.

Click here to read the entire abstract

Pubmed Data : Oxid Med Cell Longev. 2010 Jan-Feb;3(1):35-43. PMID: 20716926

Article Published Date : Jan 01, 2010

Study Type : In Vitro Study

Additional Links

Substances : Tocotrienol: Gamma : CK(25) : AC(12)

Diseases : Aging : CK(1399) : AC(392), Oxidative Stress : CK(2855) : AC(750)

Pharmacological Actions : Antioxidants : CK(5301) : AC(1618), Telomerase Upregulation : CK(101) : AC(27)

Additional Keywords : Telomere Length : CK(18) : AC(5), Upregulation of Telemere Length : CK(4) : AC(3)

Ginkgo biloba extract reduces endothelial progenitor-cell aging through augmentation of telomerase activity.

Click here to read the entire abstract

Pubmed Data : J Cardiovasc Pharmacol. 2007 Feb;49(2):111-5. PMID: 17312453

Article Published Date : Feb 01, 2007

Study Type : In Vitro Study

Additional Links

Substances : Ginkgo biloba : CK(687) : AC(108)

Diseases : Aging : CK(1399) : AC(392), Endothelial Dysfunction : CK(1079) : AC(181)

Pharmacological Actions : Telomerase Upregulation : CK(101) : AC(27)

Additional Keywords : Plant Extracts : CK(5359) : AC(1705)

Melatonin may treat or prevent age-related macular degeneration through stimulation of telomerase activity.

Click here to read the entire abstract

Pubmed Data : Med Hypotheses. 2011 Jan;76(1):79-85. Epub 2010 Sep 29. PMID: 20884126

Article Published Date : Jan 01, 2011

Study Type : In Vitro Study

Additional Links

Substances : Melatonin : CK(679) : AC(132)

Diseases : Macular Degeneration : CK(172) : AC(26)

Pharmacological Actions : Enzyme Inhibitors : CK(417) : AC(225), Telomerase Upregulation : CK(101) : AC(27), Vascular Endothelial Growth Factor A Inhibitor : CK(112) : AC(63)

Rejuvenation of aged tissues may be possible through telomerase reactivation.

Click here to read the entire abstract

Pubmed Data : Rejuvenation Res. 2010 Dec;13(6):749-54. PMID: 21226558

Article Published Date : Dec 01, 2010

Study Type : Review

Additional Links

Diseases : Aging : CK(1399) : AC(392)

Pharmacological Actions : Telomerase Upregulation : CK(101) : AC(27)

Resveratrol may have therapeutic value in Werner syndrome.

Click here to read the entire abstract

Pubmed Data : Curr Aging Sci. 2011 Feb 1;4(1):1-7. PMID: 21204775

Article Published Date : Feb 01, 2011

Study Type : In Vitro Study

Additional Links

Substances : Resveratrol : CK(1100) : AC(603)

Diseases : Werner Syndrome : CK(3) : AC(2)

Pharmacological Actions : Telomerase Upregulation : CK(101) : AC(27)

Resveratrol reduces aging via telomerase activation.

Click here to read the entire abstract

Pubmed Data : Br J Pharmacol. 2008 Jun 30. PMID: 18587418

Article Published Date : Jun 30, 2008

Study Type : In Vitro Study

Additional Links

Substances : Resveratrol : CK(1100) : AC(603)

Diseases : Aging : CK(1399) : AC(392)

Pharmacological Actions : Telomerase Upregulation : CK(101) : AC(27)

Health Guide: Aging Research

Print Options

Some features are currently member only features. If you are already a member, please login. Otherwise, click here to become a member.

Printer-friendly version
Send to friend
PDF version

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.
© Copyright 2008-2015 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.