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Additional Topics Details for this Page
Article Count
- 348
Cumulative Knowledge
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View the Evidence: Pharmacological Actions
A combination of lactobacillus reuteri and lactobacillus rhamnosus reduces inflammation in patients with Crohn's disease or ulcerative colitis.
Click here to read the entire abstract
Pubmed Data
: Clin Exp Immunol. 2007 Sep;149(3):470-9. Epub 2007 Jun 22. PMID:
17590176
Article Published Date
: Sep 01, 2007
Study Type
: Human Study
Additional Links
Substances
:
Lactobacillus reuteri : CK(181) : AC(25)
,
Lactobacillus rhamnosus GG : CK(211) : AC(28)
Diseases
:
Crohn's Disease : CK(122) : AC(22)
,
Inflammatory Bowel Diseases : CK(1227) : AC(103)
Pharmacological Actions
:
Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)
A standardized preparation of curcuminoids compares favorably with atorvastatin on endothelial dysfunction in association with reductions in inflammatory cytokines and markers of oxidative stress.
Click here to read the entire abstract
Pubmed Data
: Drugs R D. 2008;9(4):243-50. PMID:
18588355
Article Published Date
: Jan 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Curcumin : CK(2910) : AC(1482)
Diseases
:
Endothelial Dysfunction : CK(897) : AC(173)
,
Inflammation : CK(1077) : AC(363)
,
Oxidative Stress : CK(1945) : AC(710)
Pharmacological Actions
:
Interleukin-6 Downregulation : CK(470) : AC(135)
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)
Additional Keywords
:
Drug: Atorvastatin : CK(10) : AC(1)
,
Natural Substances Versus Drugs : CK(988) : AC(165)
,
Statin Alternatives : CK(34) : AC(4)
Adherence to a Mediterranean dietary pattern may protect against coronary artery wall production of inflammatory mediators in patients with unstable angina pectoris.
Click here to read the entire abstract
Pubmed Data
: Eur J Nutr. 2005 Sep;44(6):348-54. Epub 2004 Nov 24. PMID:
16151968
Article Published Date
: Sep 01, 2005
Study Type
: Human Study
Additional Links
Substances
:
Olive : CK(401) : AC(97)
Diseases
:
Angina Pectoris : CK(93) : AC(11)
,
Arteriosclerosis : CK(2154) : AC(123)
Therapeutic Actions
:
Dietary Modification: Mediterranean Diet : CK(500) : AC(58)
Pharmacological Actions
:
Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)
,
Vascular Cell Adhesion Molecule-1 Inhibitor : CK(94) : AC(24)
Adherence to the Mediterranean diet attenuates inflammation and coagulation process in healthy adults.
Click here to read the entire abstract
Pubmed Data
: J Am Coll Cardiol. 2004 Jul 7;44(1):152-8. PMID:
15234425
Article Published Date
: Jul 07, 2004
Study Type
: Human Study
Additional Links
Diseases
:
C-Reactive Protein : CK(819) : AC(74)
,
Inflammation : CK(1077) : AC(363)
,
Thrombosis : CK(657) : AC(74)
Therapeutic Actions
:
Dietary Modification: Mediterranean Diet : CK(500) : AC(58)
Pharmacological Actions
:
Anti-thrombotic : CK(44) : AC(21)
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)
An elemental diet reduces mucosal inflammation in patients with active Crohn's disease with remission occuring in 71% of patients.
Click here to read the entire abstract
Pubmed Data
: Inflamm Bowel Dis. 2005 Jun;11(6):580-8. PMID:
15905706
Article Published Date
: Jun 01, 2005
Study Type
: Human Study
Additional Links
Diseases
:
Inflammation : CK(1077) : AC(363)
Therapeutic Actions
:
Dietary Modification: Elemental Diet : CK(145) : AC(17)
Pharmacological Actions
:
Interleukin-1 receptor antagonist : CK(11) : AC(2)
,
Interleukin-6 Downregulation : CK(470) : AC(135)
,
Interleukin-8 downregulation : CK(97) : AC(28)
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)
Association of endodontic infection with detection of an initial lesion to the cardiovascular system.
Click here to read the entire abstract
Pubmed Data
: J Endod. 2011 Dec ;37(12):1624-9. PMID:
22099894
Article Published Date
: Dec 01, 2011
Study Type
: Human Study
Additional Links
Diseases
:
Periodontal Diseases : CK(134) : AC(34)
Pharmacological Actions
:
Interleukin-6 Downregulation : CK(470) : AC(135)
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)
Astaxanthin addition improves human neutrophils function.
Click here to read the entire abstract
Pubmed Data
: Eur J Nutr. 2010 Dec;49(8):447-57. Epub 2010 Apr 2. PMID:
20361333
Article Published Date
: Dec 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Astaxanthin : CK(353) : AC(117)
Diseases
:
Immune Disorders: Low Immune Function : CK(488) : AC(115)
,
Oxidative Stress : CK(1945) : AC(710)
Pharmacological Actions
:
Antioxidants : CK(3653) : AC(1318)
,
Immunostimulatory : CK(143) : AC(33)
,
Interleukin-6 Downregulation : CK(470) : AC(135)
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)
Astragalus improves cardiac function in aged patients with Chronic Heart Failure.
Click here to read the entire abstract
Pubmed Data
: Chin J Integr Med. 2005 Sep;11(3):187-90. PMID:
16181532
Article Published Date
: Sep 01, 2005
Study Type
: Human Study
Additional Links
Substances
:
Astragalus : CK(225) : AC(49)
Diseases
:
Heart Failure : CK(711) : AC(97)
Pharmacological Actions
:
Interleukin-6 Downregulation : CK(470) : AC(135)
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)
Astragalus may significantly improve Chronic Aplastic Anemia via recovery of hemopoietic function.
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2004 May;92(1):93-101. PMID:
17609906
Article Published Date
: May 01, 2004
Study Type
: Human Study
Additional Links
Substances
:
Astragalus : CK(225) : AC(49)
Diseases
:
Anemia: Aplastic : CK(30) : AC(3)
Pharmacological Actions
:
Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)
Bacillus coagulans increased immune response (enhanced T-cell response) to viral challenge.
Click here to read the entire abstract
Pubmed Data
: Postgrad Med. 2009 Mar;121(2):114-8. PMID:
19332969
Article Published Date
: Mar 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Bacillus coagulans : CK(41) : AC(5)
Diseases
:
Immune Disorders: Low Immune Function : CK(488) : AC(115)
,
Respiratory Tract Infections : CK(123) : AC(13)
Pharmacological Actions
:
Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)
Bloodroot and echinacea offset exercise-associated effects of immune activity.
Click here to read the entire abstract
Pubmed Data
: Blood Cells Mol Dis. 2009 Nov-Dec;43(3):298-303. Epub 2009 Sep 19. PMID:
19766513
Article Published Date
: Nov 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Bloodroot : CK(25) : AC(6)
,
Echinacea : CK(469) : AC(88)
Diseases
:
Immune Disorders: Low Immune Function : CK(488) : AC(115)
,
Low Immune Function: Exercise-Induced : CK(40) : AC(4)
Pharmacological Actions
:
Immunomodulatory : CK(536) : AC(142)
,
Immunostimulatory : CK(143) : AC(33)
,
Interleukin-1 beta downregulation : CK(177) : AC(70)
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)
Additional Keywords
:
Plant Extracts : CK(3572) : AC(1216)
Breastfeeding attenuates reductions in energy intake induced by a mild immunologic stimulus represented by DPTH immunization.
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2002 Jun;132(6):1293-8. PMID:
12042449
Article Published Date
: Jun 01, 2002
Study Type
: Human Study
Additional Links
Substances
:
Breast Milk : CK(428) : AC(49)
Diseases
:
Vaccine-induced Toxicity : CK(1130) : AC(163)
Therapeutic Actions
:
Breastfeeding : CK(708) : AC(67)
Pharmacological Actions
:
Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)
Anti Therapeutic Actions
:
Vaccination: All : CK(3830) : AC(302)
,
Vaccination: Diphtheria-Pertussis-Tetanus : CK(283) : AC(31)
Breastfeeding protects against illness-induced anorexia and is mediated partially by docosahexaenoic acid.
Click here to read the entire abstract
Pubmed Data
: Eur J Clin Nutr. 2008 Jan;62(1):32-8. Epub 2007 Feb 21. PMID:
17311056
Article Published Date
: Jan 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Breast Milk : CK(428) : AC(49)
,
DHA (Docosahexaenoic Acid) : CK(582) : AC(100)
Diseases
:
Anorexia: Illness and Vaccine Induced : CK(10) : AC(1)
,
Vaccine-induced Toxicity : CK(1130) : AC(163)
Therapeutic Actions
:
Breastfeeding : CK(708) : AC(67)
Pharmacological Actions
:
Interleukin-1 beta downregulation : CK(177) : AC(70)
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)
Cannabis use significantly reduces symptoms, and reduces the requirements for drugs and surgery in subjects with Crohn's disease.
Click here to read the entire abstract
Pubmed Data
: Isr Med Assoc J. 2011 Aug ;13(8):455-8. PMID:
21910367
Article Published Date
: Aug 01, 2011
Study Type
: Human Study
Additional Links
Substances
:
Cannabis : CK(738) : AC(132)
Pharmacological Actions
:
Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)
Additional Keywords
:
Drug Sparing : CK(451) : AC(49)
Cats claw is an effective treatment for osteoarthritis.
Click here to read the entire abstract
Pubmed Data
: Inflamm Res. 2001 Sep;50(9):442-8. PMID:
11603848
Article Published Date
: Sep 01, 2001
Study Type
: Human Study
Additional Links
Substances
:
Cat's Claw : CK(44) : AC(22)
Diseases
:
Osteoarthritis : CK(615) : AC(91)
,
Osteoarthritis: Knee : CK(357) : AC(38)
Pharmacological Actions
:
Anti-Inflammatory Agents : CK(1230) : AC(433)
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)
Chronic insomnia is associated with a shift of interleukin-6 and tumor necrosis factor secretion from nighttime to daytime.
Click here to read the entire abstract
Pubmed Data
: Metabolism. 2002 Jul;51(7):887-92. PMID:
12077736
Article Published Date
: Jul 01, 2002
Study Type
: Human Study
Additional Links
Diseases
:
Insomnia : CK(471) : AC(56)
Pharmacological Actions
:
Interleukin-6 Downregulation : CK(470) : AC(135)
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)
Cycling and Tai Chi Chuan exercises suppress human hepatitis B virus surface antigen.
Click here to read the entire abstract
Pubmed Data
: Chin Med J (Engl). 2008 Nov 5;121(21):2172-9. PMID:
19080180
Article Published Date
: Nov 05, 2008
Study Type
: Human Study
Additional Links
Diseases
:
Hepatitis B : CK(226) : AC(39)
Therapeutic Actions
:
Exercise: Cycling : CK(30) : AC(3)
,
Tai Chi : CK(382) : AC(38)
Pharmacological Actions
:
Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)
DHA supplementation reduces the production of inflammatory mediators and decreases the adverse effect of infection on appetite.
Click here to read the entire abstract
Pubmed Data
: Rev Med Inst Mex Seguro Soc. 2006 Jan-Feb;44(1):5-11. PMID: 1
16497254
Article Published Date
: Jan 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
DHA (Docosahexaenoic Acid) : CK(582) : AC(100)
Diseases
:
Pneumonia : CK(330) : AC(40)
Pharmacological Actions
:
Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)
DHEA administration counteracts oxidative imbalance and advanced glycation end product formation in type 2 diabetic patients.
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2009 Mar;23(3):303-7. PMID:
17704347
Article Published Date
: Mar 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
DHEA (Dehydroepiandrosterone) : CK(230) : AC(37)
Diseases
:
Advanced Glycation End products (AGE) : CK(2114) : AC(40)
,
Diabetes Mellitus: Type 2 : CK(3429) : AC(341)
Pharmacological Actions
:
Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)
Dietary lipids and their inflammatory potential may be implicated in the link between elevated body mass and asthma.
Click here to read the entire abstract
Pubmed Data
: Ann Allergy Asthma Immunol. 2003 Apr;90(4):371-7; quiz 377-8, 421. PMID:
12722956
Article Published Date
: Apr 01, 2003
Study Type
: Human Study
Additional Links
Substances
:
Fish Oil : CK(615) : AC(95)
,
Omega-3 Fatty Acids : CK(3333) : AC(319)
Diseases
:
Asthma : CK(918) : AC(134)
,
Inflammation : CK(1077) : AC(363)
,
Obesity : CK(1849) : AC(275)
Therapeutic Actions
:
Dietary Modification: Non-Western Diet : CK(40) : AC(4)
Pharmacological Actions
:
Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)
Additional Keywords
:
Obesity-Asthma-Inflammation Link : CK(110) : AC(17)
Dietary soy improves the inflammatory and nutritional status in end-stage renal disease patients on chronic hemodialysis
Click here to read the entire abstract
Pubmed Data
: Nephrol Dial Transplant. 2006 Aug;21(8):2239-46. Epub 2006 Jun 9. PMID:
16766544
Article Published Date
: Aug 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Isoflavones : CK(627) : AC(124)
Diseases
:
C-Reactive Protein : CK(819) : AC(74)
,
Hemodialysis : CK(393) : AC(38)
,
Inflammation : CK(1077) : AC(363)
,
Kidney Failure : CK(668) : AC(41)
Pharmacological Actions
:
Interleukin-6 Downregulation : CK(470) : AC(135)
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)
Echinacea modules human gene expression in a manner consistent with its reported ability to reduce both the duration and intensity of cold and flu symptoms.
Click here to read the entire abstract
Pubmed Data
: Exp Biol Med (Maywood). 2003 Oct;228(9):1051-6. PMID:
14530514
Article Published Date
: Oct 01, 2003
Study Type
: Human Study
Additional Links
Substances
:
Echinacea : CK(469) : AC(88)
Diseases
:
Cold and Flu : CK(1095) : AC(146)
,
Common Cold : CK(473) : AC(56)
,
Upper Respiratory Infections : CK(972) : AC(92)
Pharmacological Actions
:
Interferon Inducers : CK(31) : AC(9)
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)
Additional Keywords
:
Plant Extracts : CK(3572) : AC(1216)
Electroacupuncture can significantly decrease permeability of intestinal mucosa in the patients with acute pancreatitis.
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhen Jiu. 2007 Jun;27(6):421-3. PMID:
17663105
Article Published Date
: Jun 01, 2007
Study Type
: Human Study
Additional Links
Diseases
:
Intestinal Permeability : CK(224) : AC(53)
,
Pancreatitis : CK(164) : AC(40)
Therapeutic Actions
:
Electroacupuncture : CK(262) : AC(34)
Pharmacological Actions
:
Anti-Inflammatory Agents : CK(1230) : AC(433)
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)
Electroacupuncture has a therapeutic effect on patients wtih osteoarthritis.
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhen Jiu. 2009 Jul;29(7):529-31. PMID:
19835118
Article Published Date
: Jul 01, 2009
Study Type
: Human Study
Additional Links
Diseases
:
Osteoarthritis : CK(615) : AC(91)
Pharmacological Actions
:
Interleukin-1 beta downregulation : CK(177) : AC(70)
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)
Fasting and a one-year vegetarian diet can reduce disease activity in some patients with rheumatoid arthritis.
Click here to read the entire abstract
Pubmed Data
: Scand J Rheumatol. 1995;24(2):85-93. PMID:
7747149
Article Published Date
: Jan 01, 1995
Study Type
: Human Study
Additional Links
Diseases
:
Rheumatoid Arthritis : CK(424) : AC(64)
Therapeutic Actions
:
Dietary Modification: Vegetarian : CK(116) : AC(15)
,
Fasting/Caloric Restriction : CK(235) : AC(50)
Pharmacological Actions
:
Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)
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