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Antidiarrheals [1]

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Quick Summary: 21 associated Substances
NameCumulative KnowledgeAbstract CountFocus Articles
Banana324 [2] | [8]
Probiotics202 [2] | [8]
Black Tea122 [2] | [8]
Lactobacillus rhamnosus 122 [2] | [8]
Bacillus coagulans101 [2] | [8]
Homeopathic Medicine: All101 [2] | [8]
Lactobacillus helveticus101 [2] | [8]
Pectin101 [2] | [8]
Polyphenols101 [2] | [8]
White Pepper101 [2] | [8]
Apple Polyphenols21 [2] | [8]
Berberine21 [2] | [8]
Catechin 21 [2] | [8]
Curry Tree21 [2] | [8]
Cyperus rotundus21 [2] | [8]
Flavonoids21 [2] | [8]
Grapefruit21 [2] | [8]
Psychedelics:All 21 [2] | [8]
Rice Bran21 [2] | [8]
Sweet Orange21 [2] | [8]
Holarrhena antidysenterica11 [2] | [8]

View the Evidence: Pharmacological Actions

B. coagulans MTCC 5856 could be a potential agent in the management of diarrhea predominant IBS patients. [11]

Article Publish Status : This is a free article. Click here to read the complete article. [12]
Pubmed Data : Nutr J. 2016 ;15(1):21. Epub 2016 Feb 27. PMID: 26922379 [13]
Article Published Date : Dec 31, 2015
Study Type : Human Study
Additional Links
Substances : Bacillus coagulans : CK(41) : AC(5) [14], Probiotics : CK(2868) : AC(364) [15]
Diseases : Diarrhea: IBS associated : CK(32) : AC(4) [16]
Pharmacological Actions : Antidiarrheals : CK(110) : AC(20) [1]
Additional Keywords : Significant Treatment Outcome : CK(3038) : AC(366) [17]

Green banana and pectin are useful in the dietary management of persistent diarrhea in hospitalized children and may also be useful to treat children at home. [18]

Pubmed Data : Gastroenterology. 2001 Sep;121(3):554-60. PMID: 11522739 [19]
Article Published Date : Sep 01, 2001
Study Type : Human Study
Additional Links
Substances : Banana : CK(194) : AC(53) [20], Pectin : CK(66) : AC(9) [21]
Diseases : Childhood Infections : CK(275) : AC(29) [22], Diarrhea : CK(612) : AC(83) [23], Diarrhea: in Children : CK(223) : AC(22) [24]
Pharmacological Actions : Antidiarrheals : CK(110) : AC(20) [1]

Green banana and pectin improve small intestinal permeability and reduce fluid loss in Bangladeshi children with persistent diarrhea. [25]

Pubmed Data : Dig Dis Sci. 2004 Mar;49(3):475-84. PMID: 15139502 [26]
Article Published Date : Mar 01, 2004
Study Type : Human Study
Additional Links
Substances : Banana : CK(194) : AC(53) [20]
Diseases : Diarrhea : CK(612) : AC(83) [23], Diarrhea: in Children : CK(223) : AC(22) [24], Intestinal Permeability : CK(245) : AC(60) [27]
Pharmacological Actions : Antidiarrheals : CK(110) : AC(20) [1]

Green banana speeds the recovery of acute and prolonged diarrhea in children. [28]

Pubmed Data : Trop Med Int Health. 2010 Oct;15(10):1132-9. PMID: 20831671 [29]
Article Published Date : Oct 01, 2010
Study Type : Human Study
Additional Links
Substances : Banana : CK(194) : AC(53) [20]
Diseases : Diarrhea : CK(612) : AC(83) [23], Diarrhea: in Children : CK(223) : AC(22) [24]
Pharmacological Actions : Antidiarrheals : CK(110) : AC(20) [1]

Homeopathic treatment has therapeutic value in acute childhood diarrhea. [30]

Pubmed Data : J Invest Dermatol. 2008 Oct;128(10):2429-41. Epub 2008 May 8. PMID: 10784270 [31]
Article Published Date : Oct 01, 2008
Study Type : Human Study
Additional Links
Substances : Homeopathic Medicine: All : CK(927) : AC(100) [32]
Diseases : Diarrhea : CK(612) : AC(83) [23], Diarrhea: in Children : CK(223) : AC(22) [24]
Therapeutic Actions : Homeopathic Treatment : CK(658) : AC(72) [33]
Pharmacological Actions : Antidiarrheals : CK(110) : AC(20) [1]

Lactobacillus helveticus and Lactobacillus rhamnosus could be used for the management of antibiotic-associated diarrhoea. [34]

Pubmed Data : Br J Nutr. 2016 Jul ;116(1):94-103. Epub 2016 May 12. PMID: 27169634 [35]
Article Published Date : Jun 30, 2016
Study Type : Human Study
Additional Links
Substances : Lactobacillus helveticus : CK(11) : AC(2) [36], Lactobacillus rhamnosus : CK(125) : AC(20) [37], Probiotics : CK(2868) : AC(364) [15]
Diseases : Diarrhea: Antibiotic-Associated : CK(41) : AC(5) [38]
Pharmacological Actions : Antidiarrheals : CK(110) : AC(20) [1]

Significant decreases in bowel movement frequency and rapid normalization of stool consistency were observed with consumption of this novel solution. [39]

Article Publish Status : This is a free article. Click here to read the complete article. [40]
Pubmed Data : PeerJ. 2015 ;3:e969. Epub 2015 May 21. PMID: 26038724 [41]
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Polyphenols : CK(931) : AC(335) [42]
Diseases : Diarrhea : CK(612) : AC(83) [23], Diarrhea: in Children : CK(223) : AC(22) [24]
Pharmacological Actions : Antidiarrheals : CK(110) : AC(20) [1], Gastrointestinal Agents : CK(268) : AC(41) [43]
Additional Keywords : Significant Treatment Outcome : CK(3038) : AC(366) [17]

Stir-fried white pepper significantly decreased the frequency of diarrhea in infants and children under 2.5 years with diarrhea compared to treatment with montmorillonite powder. [44]

Pubmed Data : Am J Chin Med. 2013 ;41(4):765-72. PMID: 23895150 [45]
Article Published Date : Dec 31, 2012
Study Type : Human Study
Additional Links
Substances : White Pepper : CK(10) : AC(1) [46]
Diseases : Diarrhea : CK(612) : AC(83) [23]
Pharmacological Actions : Antidiarrheals : CK(110) : AC(20) [1]
Additional Keywords : Phytotherapy : CK(1216) : AC(221) [47]

This study found a possible antidiarrheal effect of black tea. [48]

Pubmed Data : J Evid Based Complementary Altern Med. 2016 Jun 19. Epub 2016 Jun 19. PMID: 27324724 [49]
Article Published Date : Jun 18, 2016
Study Type : Human Study
Additional Links
Substances : Black Tea : CK(360) : AC(80) [50]
Diseases : Diarrhea : CK(612) : AC(83) [23]
Pharmacological Actions : Antidiarrheals : CK(110) : AC(20) [1]

A Murraya koenigii extract of leaves possessed significant anti-diarrheal activity. [51]

Pubmed Data : J Diet Suppl. 2015 Dec 2:1-8. Epub 2015 Dec 2. PMID: 26631977 [52]
Article Published Date : Dec 01, 2015
Study Type : Animal Study
Additional Links
Substances : Curry Tree : CK(2) : AC(1) [53]
Diseases : Diarrhea : CK(612) : AC(83) [23]
Pharmacological Actions : Antidiarrheals : CK(110) : AC(20) [1]
Additional Keywords : Plant Extracts : CK(7484) : AC(2463) [54]

Berberine reduces thyroxine-induced diarrhea in rats. [55]

Pubmed Data : J Korean Med Sci. 2001 Dec;16 Suppl:S42-53. PMID: 19323986 [56]
Article Published Date : Dec 01, 2001
Study Type : Animal Study
Additional Links
Substances : Berberine : CK(325) : AC(166) [57]
Diseases : Diarrhea: Drug-Associated : CK(22) : AC(2) [58], Drug-Induced Toxicity: L-Thyroxine : CK(18) : AC(6) [59]
Pharmacological Actions : Antidiarrheals : CK(110) : AC(20) [1]

C. zacatechichi DCM extract exhibits potent action in the GI tract and produces a significant antidiarrheal and antinociceptive effect in mouse models mimicking IBS. [60]

Article Publish Status : This is a free article. Click here to read the complete article. [61]
Pubmed Data : Naunyn Schmiedebergs Arch Pharmacol. 2015 Oct ;388(10):1069-77. Epub 2015 Jun 12. PMID: 26068703 [62]
Article Published Date : Sep 30, 2015
Study Type : Animal Study
Additional Links
Substances : Psychedelics:All : CK(18) : AC(6) [63]
Diseases : Irritable Bowel Syndrome : CK(710) : AC(92) [64]
Pharmacological Actions : Analgesics : CK(1327) : AC(217) [65], Antidiarrheals : CK(110) : AC(20) [1], Antinoceceptive : CK(193) : AC(51) [66]
Additional Keywords : Folk Medicine : CK(7) : AC(4) [67], Plant Extracts : CK(7484) : AC(2463) [54]

Citrus bioflavonoids from orange and grapefruit could be useful in the management of inflammatory bowel diseases. [68]

Pubmed Data : Pak J Pharm Sci. 2016 May ;29(3):843-52. PMID: 27166529 [69]
Article Published Date : Apr 30, 2016
Study Type : Animal Study
Additional Links
Substances : Grapefruit : CK(130) : AC(33) [70], Sweet Orange : CK(26) : AC(5) [71]
Diseases : Colitis : CK(255) : AC(111) [72], Diarrhea: IBS associated : CK(32) : AC(4) [16], Gastrointestinal Inflammation : CK(116) : AC(39) [73], Inflammatory Bowel Diseases : CK(1013) : AC(190) [74]
Pharmacological Actions : Anti-Inflammatory Agents : CK(4861) : AC(1630) [75], Antidiarrheals : CK(110) : AC(20) [1], Antioxidants : CK(7529) : AC(2682) [76]

Cyperus rotundus exhibits antidiarrheal activity. [77]

Pubmed Data : Fitoterapia. 2006 Feb;77(2):134-6. Epub 2005 Dec 20. PMID: 16376024 [78]
Article Published Date : Feb 01, 2006
Study Type : Animal Study
Additional Links
Substances : Cyperus rotundus : CK(7) : AC(4) [79]
Diseases : Diarrhea : CK(612) : AC(83) [23]
Pharmacological Actions : Antidiarrheals : CK(110) : AC(20) [1]
Additional Keywords : Plant Extracts : CK(7484) : AC(2463) [54]

Polymerized catechin compounds in apple polyphenol extracts inhibit the biological and enzymatic activities of cholera toxin. [80]

Article Publish Status : This is a free article. Click here to read the complete article. [81]
Pubmed Data : Microbiol Immunol. 2002 ;46(4):249-55. PMID: 12061627 [82]
Article Published Date : Dec 31, 2001
Study Type : Animal Study
Additional Links
Substances : Apple Polyphenols : CK(31) : AC(17) [83], Catechin : CK(512) : AC(169) [84], Flavonoids : CK(1215) : AC(379) [85]
Diseases : Cholera : CK(66) : AC(24) [86]
Pharmacological Actions : Antidiarrheals : CK(110) : AC(20) [1], Antimicrobial : CK(293) : AC(128) [87], Enzyme Inhibitors : CK(473) : AC(251) [88]
Additional Keywords : Dose Response : CK(1056) : AC(408) [89], Plant Extracts : CK(7484) : AC(2463) [54]

Rice bran, Lactobacillus rhamnosus and Escherichia coli Nissle was highly effective against diarrhea and infection caused by human rotavirus. [90]

Article Publish Status : This is a free article. Click here to read the complete article. [91]
Pubmed Data : Sci Rep. 2015 ;5:15004. Epub 2015 Oct 13. PMID: 26459937 [92]
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Lactobacillus rhamnosus : CK(125) : AC(20) [37], Rice Bran : CK(127) : AC(37) [93]
Diseases : Diarrhea : CK(612) : AC(83) [23], Rotavirus Infections : CK(102) : AC(24) [94]
Pharmacological Actions : Antidiarrheals : CK(110) : AC(20) [1], Gastrointestinal Agents : CK(268) : AC(41) [43]

The hot water extract of black tea exhibits antidiarrheal activity, possibly through interacting with the opiod system. [95]

Pubmed Data : Phytother Res. 2003 Apr;17(4):380-4. PMID: 12722145 [96]
Article Published Date : Apr 01, 2003
Study Type : Animal Study
Additional Links
Substances : Black Tea : CK(360) : AC(80) [50]
Diseases : Diarrhea : CK(612) : AC(83) [23]
Pharmacological Actions : Antidiarrheals : CK(110) : AC(20) [1]
Additional Keywords : Plant Extracts : CK(7484) : AC(2463) [54]

The sap of Musa paradisiaca in the folk medicine as a nonspecific antidiarrhoeal agent has been substantiated with scientific evidence. [97]

Article Publish Status : This is a free article. Click here to read the complete article. [98]
Pubmed Data : Evid Based Complement Alternat Med. 2015 ;2015:683726. Epub 2015 Mar 29. PMID: 25893000 [99]
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Banana : CK(194) : AC(53) [20]
Diseases : Diarrhea : CK(612) : AC(83) [23]
Pharmacological Actions : Antidiarrheals : CK(110) : AC(20) [1]
Additional Keywords : Folk Medicine : CK(7) : AC(4) [67]

Acorus calamus has antispasmodic activitity mediated through calcium channel blockade, confirming its traditional use for gastrointestinal disorders such as colic pain and diarrhea. [100]

Pubmed Data : Phytother Res. 2006 Dec;20(12):1080-4. PMID: 17009206 [101]
Article Published Date : Dec 01, 2006
Study Type : In Vitro Study
Additional Links
Diseases : Colic : CK(135) : AC(18) [102], Diarrhea : CK(612) : AC(83) [23]
Pharmacological Actions : Antidiarrheals : CK(110) : AC(20) [1], Calcium Channel Blockers : CK(87) : AC(23) [103]
Additional Keywords : Plant Extracts : CK(7484) : AC(2463) [54]

Holarrhena antidysenterica exhibits antidiarrheal and antibacterial activity against E. coli. [104]

Pubmed Data : Indian J Exp Biol. 2004 Jun;42(6):589-94. PMID: 15260110 [105]
Article Published Date : Jun 01, 2004
Study Type : In Vitro Study
Additional Links
Substances : Holarrhena antidysenterica : CK(3) : AC(3) [106]
Diseases : Diarrhea : CK(612) : AC(83) [23], Escherichia coli Infections : CK(152) : AC(90) [107]
Pharmacological Actions : Anti-Bacterial Agents : CK(1367) : AC(475) [108], Antidiarrheals : CK(110) : AC(20) [1]
Additional Keywords : Plant Extracts : CK(7484) : AC(2463) [54]
Source URL: http://www.greenmedinfo.com/pharmacological-action/antidiarrheals

Links:
[1] http://www.greenmedinfo.com/pharmacological-action/antidiarrheals
[2] http://www.greenmedinfo.com/user/login?destination=print%2Fpharmacological-action%2Fantidiarrheals
[3] http://www.greenmedinfo.com/node/53860/0);
[4] http://www.greenmedinfo.com/node
[5] http://www.greenmedinfo.com/gmi-professional/pdf
[6] http://www.greenmedinfo.com/content/subscription-options-becoming-basic-member-unpublished
[7] http://www.greenmedinfo.com/page/cumulative-knowledge-explained
[8] http://www.greenmedinfo.com/page/greenmedinfo-memberships
[9] http://www.greenmedinfo.com/page/become-greenmedinfo-professional-member-full
[10] http://www.greenmedinfo.com/page/gmi-friend-membership
[11] http://www.greenmedinfo.com/article/b-coagulans-mtcc-5856-could-be-potential-agent-management-diarrhea-predominant
[12] http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769834/
[13] http://www.ncbi.nlm.nih.gov/pubmed/26922379
[14] http://www.greenmedinfo.com/substance/bacillus-coagulans
[15] http://www.greenmedinfo.com/substance/probiotics
[16] http://www.greenmedinfo.com/disease/diarrhea-ibs-associated
[17] http://www.greenmedinfo.com/keyword/significant-treatment-outcome
[18] http://www.greenmedinfo.com/article/green-banana-and-pectin-are-useful-dietary-management-persistent-diarrhea
[19] http://www.ncbi.nlm.nih.gov/pubmed/11522739
[20] http://www.greenmedinfo.com/substance/banana
[21] http://www.greenmedinfo.com/substance/pectin
[22] http://www.greenmedinfo.com/disease/childhood-infections
[23] http://www.greenmedinfo.com/disease/diarrhea
[24] http://www.greenmedinfo.com/disease/diarrhea-children
[25] http://www.greenmedinfo.com/article/green-banana-and-pectin-improve-small-intestinal-permeability-and-reduce-fluid-loss
[26] http://www.ncbi.nlm.nih.gov/pubmed/15139502
[27] http://www.greenmedinfo.com/disease/intestinal-permeability
[28] http://www.greenmedinfo.com/article/green-banana-speeds-recovery-acute-and-prolonged-diarrhea-children
[29] http://www.ncbi.nlm.nih.gov/pubmed/20831671
[30] http://www.greenmedinfo.com/article/homeopathic-treatment-has-therapeutic-value-acute-childhood-diarrhea
[31] http://www.ncbi.nlm.nih.gov/pubmed/10784270
[32] http://www.greenmedinfo.com/substance/homeopathic-medicine-all
[33] http://www.greenmedinfo.com/therapeutic-action/homeopathic-treatment
[34] http://www.greenmedinfo.com/article/lactobacillus-helveticus-and-lactobacillus-rhamnosus-could-be-used-management-
[35] http://www.ncbi.nlm.nih.gov/pubmed/27169634
[36] http://www.greenmedinfo.com/substance/lactobacillus-helveticus
[37] http://www.greenmedinfo.com/substance/lactobacillus-rhamnosus
[38] http://www.greenmedinfo.com/disease/diarrhea-antibiotic-associated
[39] http://www.greenmedinfo.com/article/significant-decreases-bowel-movement-frequency-and-rapid-normalization-stool
[40] https://peerj.com/articles/969/
[41] http://www.ncbi.nlm.nih.gov/pubmed/26038724
[42] http://www.greenmedinfo.com/substance/polyphenols
[43] http://www.greenmedinfo.com/pharmacological-action/gastrointestinal-agents
[44] http://www.greenmedinfo.com/article/stir-fried-white-pepper-significantly-decreased-frequency-diarrhea-infants-and
[45] http://www.ncbi.nlm.nih.gov/pubmed/23895150
[46] http://www.greenmedinfo.com/keyword/white-pepper
[47] http://www.greenmedinfo.com/keyword/phytotherapy
[48] http://www.greenmedinfo.com/article/study-found-possible-antidiarrheal-effect-black-tea
[49] http://www.ncbi.nlm.nih.gov/pubmed/27324724
[50] http://www.greenmedinfo.com/substance/black-tea
[51] http://www.greenmedinfo.com/article/murraya-koenigii-extract-leaves-possessed-significant-anti-diarrheal-activity
[52] http://www.ncbi.nlm.nih.gov/pubmed/26631977
[53] http://www.greenmedinfo.com/substance/curry-tree
[54] http://www.greenmedinfo.com/keyword/plant-extracts
[55] http://www.greenmedinfo.com/article/berberine-reduces-thyroxine-induced-diarrhea-rats
[56] http://www.ncbi.nlm.nih.gov/pubmed/19323986
[57] http://www.greenmedinfo.com/substance/berberine
[58] http://www.greenmedinfo.com/disease/diarrhea-drug-associated
[59] http://www.greenmedinfo.com/disease/drug-induced-toxicity-l-thyroxine
[60] http://www.greenmedinfo.com/article/c-zacatechichi-dcm-extract-exhibits-potent-action-gi-tract-and-produces
[61] http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561081/
[62] http://www.ncbi.nlm.nih.gov/pubmed/26068703
[63] http://www.greenmedinfo.com/substance/psychedelicsall
[64] http://www.greenmedinfo.com/disease/irritable-bowel-syndrome
[65] http://www.greenmedinfo.com/pharmacological-action/analgesics
[66] http://www.greenmedinfo.com/pharmacological-action/antinoceceptive
[67] http://www.greenmedinfo.com/keyword/folk-medicine
[68] http://www.greenmedinfo.com/article/citrus-bioflavonoids-orange-and-grapefruit-could-be-useful-management-inflamma
[69] http://www.ncbi.nlm.nih.gov/pubmed/27166529
[70] http://www.greenmedinfo.com/substance/grapefruit
[71] http://www.greenmedinfo.com/substance/sweet-orange
[72] http://www.greenmedinfo.com/disease/colitis
[73] http://www.greenmedinfo.com/disease/gastrointestinal-inflammation
[74] http://www.greenmedinfo.com/disease/inflammatory-bowel-diseases
[75] http://www.greenmedinfo.com/pharmacological-action/anti-inflammatory-agents
[76] http://www.greenmedinfo.com/pharmacological-action/antioxidants
[77] http://www.greenmedinfo.com/article/cyperus-rotundus-exhibits-antidiarrheal-activity
[78] http://www.ncbi.nlm.nih.gov/pubmed/16376024
[79] http://www.greenmedinfo.com/substance/cyperus-rotundus
[80] http://www.greenmedinfo.com/article/polymerized-catechin-compounds-apple-polyphenol-extracts-inhibit-biological
[81] http://onlinelibrary.wiley.com/doi/10.1111/j.1348-0421.2002.tb02693.x/pdf
[82] http://www.ncbi.nlm.nih.gov/pubmed/12061627
[83] http://www.greenmedinfo.com/substance/apple-polyphenols
[84] http://www.greenmedinfo.com/substance/catechin
[85] http://www.greenmedinfo.com/substance/flavonoids
[86] http://www.greenmedinfo.com/disease/cholera
[87] http://www.greenmedinfo.com/pharmacological-action/antimicrobial
[88] http://www.greenmedinfo.com/pharmacological-action/enzyme-inhibitors
[89] http://www.greenmedinfo.com/keyword/dose-response
[90] http://www.greenmedinfo.com/article/rice-bran-lactobacillus-rhamnosus-and-escherichia-coli-nissle-was-highly
[91] http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602212/
[92] http://www.ncbi.nlm.nih.gov/pubmed/26459937
[93] http://www.greenmedinfo.com/substance/rice-bran
[94] http://www.greenmedinfo.com/disease/rotavirus-infections
[95] http://www.greenmedinfo.com/article/hot-water-extract-black-tea-exhibits-antidiarrheal-activity-possibly-through
[96] http://www.ncbi.nlm.nih.gov/pubmed/12722145
[97] http://www.greenmedinfo.com/article/sap-musa-paradisiaca-folk-medicine-nonspecific-antidiarrhoeal-agent-has-been
[98] http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393921/
[99] http://www.ncbi.nlm.nih.gov/pubmed/25893000
[100] http://www.greenmedinfo.com/article/acorus-calamus-has-antispasmodic-activitity-mediated-through-calcium-channel
[101] http://www.ncbi.nlm.nih.gov/pubmed/17009206
[102] http://www.greenmedinfo.com/disease/colic
[103] http://www.greenmedinfo.com/pharmacological-action/calcium-channel-blockers
[104] http://www.greenmedinfo.com/article/holarrhena-antidysenterica-exhibits-antidiarrheal-and-antibacterial-activity
[105] http://www.ncbi.nlm.nih.gov/pubmed/15260110
[106] http://www.greenmedinfo.com/substance/holarrhena-antidysenterica
[107] http://www.greenmedinfo.com/disease/escherichia-coli-infections
[108] http://www.greenmedinfo.com/pharmacological-action/anti-bacterial-agents