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Antidiarrheals [1]

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View the Evidence: Pharmacological Actions

Green banana and pectin are useful in the dietary management of persistent diarrhea in hospitalized children and may also be useful to treat children at home. [15]

Pubmed Data : Gastroenterology. 2001 Sep;121(3):554-60. PMID: 11522739 [16]
Article Published Date : Sep 01, 2001
Study Type : Human Study
Additional Links
Substances : Banana : CK(123) : AC(36) [17], Pectin : CK(66) : AC(9) [18]
Diseases : Childhood Infections : CK(275) : AC(29) [19], Diarrhea : CK(544) : AC(72) [20], Diarrhea: in Children : CK(213) : AC(21) [21]
Pharmacological Actions : Antidiarrheals : CK(48) : AC(9) [1]

Green banana and pectin improve small intestinal permeability and reduce fluid loss in Bangladeshi children with persistent diarrhea. [22]

Pubmed Data : Dig Dis Sci. 2004 Mar;49(3):475-84. PMID: 15139502 [23]
Article Published Date : Mar 01, 2004
Study Type : Human Study
Additional Links
Substances : Banana : CK(123) : AC(36) [17]
Diseases : Diarrhea : CK(544) : AC(72) [20], Diarrhea: in Children : CK(213) : AC(21) [21], Intestinal Permeability : CK(224) : AC(53) [24]
Pharmacological Actions : Antidiarrheals : CK(48) : AC(9) [1]

Green banana speeds the recovery of acute and prolonged diarrhea in children. [25]

Pubmed Data : Trop Med Int Health. 2010 Oct;15(10):1132-9. PMID: 20831671 [26]
Article Published Date : Oct 01, 2010
Study Type : Human Study
Additional Links
Substances : Banana : CK(123) : AC(36) [17]
Diseases : Diarrhea : CK(544) : AC(72) [20], Diarrhea: in Children : CK(213) : AC(21) [21]
Pharmacological Actions : Antidiarrheals : CK(48) : AC(9) [1]

Homeopathic treatment has therapeutic value in acute childhood diarrhea. [27]

Pubmed Data : J Invest Dermatol. 2008 Oct;128(10):2429-41. Epub 2008 May 8. PMID: 10784270 [28]
Article Published Date : Oct 01, 2008
Study Type : Human Study
Additional Links
Substances : Homeopathic Medicine: All : CK(481) : AC(47) [29]
Diseases : Diarrhea : CK(544) : AC(72) [20], Diarrhea: in Children : CK(213) : AC(21) [21]
Therapeutic Actions : Homeopathic Treatment : CK(638) : AC(70) [30]
Pharmacological Actions : Antidiarrheals : CK(48) : AC(9) [1]

Berberine reduces thyroxine-induced diarrhea in rats. [31]

Pubmed Data : J Korean Med Sci. 2001 Dec;16 Suppl:S42-53. PMID: 19323986 [32]
Article Published Date : Dec 01, 2001
Study Type : Animal Study
Additional Links
Substances : Berberine : CK(156) : AC(75) [33]
Diseases : Diarrhea: Drug-Associated : CK(22) : AC(2) [34], Drug-Induced Toxicity: L-Thyroxine : CK(23) : AC(8) [35]
Pharmacological Actions : Antidiarrheals : CK(48) : AC(9) [1]

Cyperus rotundus exhibits antidiarrheal activity. [36]

Pubmed Data : Fitoterapia. 2006 Feb;77(2):134-6. Epub 2005 Dec 20. PMID: 16376024 [37]
Article Published Date : Feb 01, 2006
Study Type : Animal Study
Additional Links
Substances : Cyperus rotundus : CK(7) : AC(4) [38]
Diseases : Diarrhea : CK(544) : AC(72) [20]
Pharmacological Actions : Antidiarrheals : CK(48) : AC(9) [1]
Additional Keywords : Plant Extracts : CK(3775) : AC(1248) [39]

The hot water extract of black tea exhibits antidiarrheal activity, possibly through interacting with the opiod system. [40]

Pubmed Data : Phytother Res. 2003 Apr;17(4):380-4. PMID: 12722145 [41]
Article Published Date : Apr 01, 2003
Study Type : Animal Study
Additional Links
Substances : Black Tea : CK(158) : AC(40) [42]
Diseases : Diarrhea : CK(544) : AC(72) [20]
Pharmacological Actions : Antidiarrheals : CK(48) : AC(9) [1]
Additional Keywords : Plant Extracts : CK(3775) : AC(1248) [39]

Acorus calamus has antispasmodic activitity mediated through calcium channel blockade, confirming its traditional use for gastrointestinal disorders such as colic pain and diarrhea. [43]

Pubmed Data : Phytother Res. 2006 Dec;20(12):1080-4. PMID: 17009206 [44]
Article Published Date : Dec 01, 2006
Study Type : In Vitro Study
Additional Links
Diseases : Colic : CK(74) : AC(12) [45], Diarrhea : CK(544) : AC(72) [20]
Pharmacological Actions : Antidiarrheals : CK(48) : AC(9) [1], Calcium Channel Blockers : CK(86) : AC(21) [46]
Additional Keywords : Plant Extracts : CK(3775) : AC(1248) [39]

Holarrhena antidysenterica exhibits antidiarrheal and antibacterial activity against E. coli. [47]

Pubmed Data : Indian J Exp Biol. 2004 Jun;42(6):589-94. PMID: 15260110 [48]
Article Published Date : Jun 01, 2004
Study Type : In Vitro Study
Additional Links
Substances : Holarrhena antidysenterica : CK(3) : AC(3) [49]
Diseases : Diarrhea : CK(544) : AC(72) [20], Escherichia coli Infections : CK(66) : AC(39) [50]
Pharmacological Actions : Anti-Bacterial Agents : CK(970) : AC(316) [51], Antidiarrheals : CK(48) : AC(9) [1]
Additional Keywords : Plant Extracts : CK(3775) : AC(1248) [39]
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[15] http://www.greenmedinfo.com/article/green-banana-and-pectin-are-useful-dietary-management-persistent-diarrhea
[16] http://www.ncbi.nlm.nih.gov/pubmed/11522739
[17] http://www.greenmedinfo.com/substance/banana
[18] http://www.greenmedinfo.com/substance/pectin
[19] http://www.greenmedinfo.com/disease/childhood-infections
[20] http://www.greenmedinfo.com/disease/diarrhea
[21] http://www.greenmedinfo.com/disease/diarrhea-children
[22] http://www.greenmedinfo.com/article/green-banana-and-pectin-improve-small-intestinal-permeability-and-reduce-fluid-loss
[23] http://www.ncbi.nlm.nih.gov/pubmed/15139502
[24] http://www.greenmedinfo.com/disease/intestinal-permeability
[25] http://www.greenmedinfo.com/article/green-banana-speeds-recovery-acute-and-prolonged-diarrhea-children
[26] http://www.ncbi.nlm.nih.gov/pubmed/20831671
[27] http://www.greenmedinfo.com/article/homeopathic-treatment-has-therapeutic-value-acute-childhood-diarrhea
[28] http://www.ncbi.nlm.nih.gov/pubmed/10784270
[29] http://www.greenmedinfo.com/substance/homeopathic-medicine-all
[30] http://www.greenmedinfo.com/therapeutic-action/homeopathic-treatment
[31] http://www.greenmedinfo.com/article/berberine-reduces-thyroxine-induced-diarrhea-rats
[32] http://www.ncbi.nlm.nih.gov/pubmed/19323986
[33] http://www.greenmedinfo.com/substance/berberine
[34] http://www.greenmedinfo.com/disease/diarrhea-drug-associated
[35] http://www.greenmedinfo.com/disease/drug-induced-toxicity-l-thyroxine
[36] http://www.greenmedinfo.com/article/cyperus-rotundus-exhibits-antidiarrheal-activity
[37] http://www.ncbi.nlm.nih.gov/pubmed/16376024
[38] http://www.greenmedinfo.com/substance/cyperus-rotundus
[39] http://www.greenmedinfo.com/keyword/plant-extracts
[40] http://www.greenmedinfo.com/article/hot-water-extract-black-tea-exhibits-antidiarrheal-activity-possibly-through
[41] http://www.ncbi.nlm.nih.gov/pubmed/12722145
[42] http://www.greenmedinfo.com/substance/black-tea
[43] http://www.greenmedinfo.com/article/acorus-calamus-has-antispasmodic-activitity-mediated-through-calcium-channel
[44] http://www.ncbi.nlm.nih.gov/pubmed/17009206
[45] http://www.greenmedinfo.com/disease/colic
[46] http://www.greenmedinfo.com/pharmacological-action/calcium-channel-blockers
[47] http://www.greenmedinfo.com/article/holarrhena-antidysenterica-exhibits-antidiarrheal-and-antibacterial-activity
[48] http://www.ncbi.nlm.nih.gov/pubmed/15260110
[49] http://www.greenmedinfo.com/substance/holarrhena-antidysenterica
[50] http://www.greenmedinfo.com/disease/escherichia-coli-infections
[51] http://www.greenmedinfo.com/pharmacological-action/anti-bacterial-agents