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Andrographis

Andrographis

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Article Count - 35
Cumulative Knowledge - 80

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View the Evidence: Substances

Andrographis has a positive effect in the treatment of acute upper respiratory tract infections and also relieves the inflammatory symptoms of sinusitis.

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Pubmed Data : Phytomedicine. 2002 Oct;9(7):589-97. PMID: 12487322

Article Published Date : Oct 01, 2002

Study Type : Human Study

Additional Links

Substances : Andrographis : CK(81) : AC(35)

Diseases : Respiratory Tract Infections : CK(123) : AC(13), Sinusitis : CK(143) : AC(15)

Andrographis has therapeutic activity against upper respiratory tract infections.

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Pubmed Data : Phytomedicine. 2010 Mar;17(3-4):178-85. Epub 2010 Jan 25. PMID: 20092985

Article Published Date : Mar 01, 2010

Study Type : Human Study

Additional Links

Substances : Andrographis : CK(81) : AC(35)

Diseases : Cold and Flu : CK(1095) : AC(146), Common Cold : CK(473) : AC(56), Influenza : CK(654) : AC(102), Upper Respiratory Infections : CK(972) : AC(92)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Andrographis reduces subjective and objective symptoms of rheumatoid arthritis.

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Pubmed Data : Clin Rheumatol. 2009 Aug;28(8):931-46. Epub 2009 Apr 29. PMID: 19408036

Article Published Date : Aug 01, 2009

Study Type : Human Study

Additional Links

Substances : Andrographis : CK(81) : AC(35)

Diseases : Rheumatoid Arthritis : CK(424) : AC(64)

Andrographis, Eleutherococcus (Siberian Ginseng), Schisandra and Glycyrrhiza (Licorice) is safe and efficacious in the management of Familial Mediterranean Fever.

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Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2008 Aug;33(16):2022-5. PMID: 12809357

Article Published Date : Aug 01, 2008

Study Type : Human Study

Additional Links

Substances : Andrographis : CK(81) : AC(35), Ginseng (Siberian) : CK(138) : AC(29), Licorice : CK(257) : AC(81), Schisandra : CK(129) : AC(43)

Diseases : Familial Mediterranean Fever : CK(11) : AC(2)

A compound within Andrographis prevent diabetic nephropathy in an animal model.

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Pubmed Data : J Ethnopharmacol. 2010 Aug 30. Epub 2010 Aug 30. PMID: 20813180

Article Published Date : Aug 30, 2010

Study Type : Animal Study

Additional Links

Substances : Andrographis : CK(81) : AC(35)

Diseases : Diabetic Nephropathy : CK(43) : AC(17), Kidney Diseases : CK(424) : AC(71), Nephropathy: Diabetic : CK(4) : AC(2)

Pharmacological Actions : Renoprotective : CK(191) : AC(90)

Andrographis and Hedyotis corymbosa in combination with curcumin have anti-malaria action.

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Pubmed Data : Phytother Res. 2004 Feb;18(2):164-8. PMID: 19216765

Article Published Date : Feb 01, 2004

Study Type : Animal Study

Additional Links

Substances : Andrographis : CK(81) : AC(35), Curcumin : CK(2910) : AC(1482), Hedyotis corymbosa : CK(3) : AC(2)

Diseases : Malaria : CK(55) : AC(25)

Additional Keywords : Natural Substance Synergy : CK(144) : AC(81), Plant Extracts : CK(3572) : AC(1216)

Andrographis does not appear to have any adverse effects on reproduction and fertility in male rats.

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Pubmed Data : Int J Toxicol. 2009 Jul-Aug;28(4):308-17. PMID: 19636073

Article Published Date : Jul 01, 2009

Study Type : Animal Study

Additional Links

Substances : Andrographis : CK(81) : AC(35)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Andrographis has a prophylactic effect against Streptococcus agalactiae infection in Nile tilapia.

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Pubmed Data : J Biosci Bioeng. 2009 May;107(5):579-82. PMID: 19393561

Article Published Date : May 01, 2009

Study Type : Animal Study

Additional Links

Substances : Andrographis : CK(81) : AC(35)

Diseases : Streptococcus Infections : CK(601) : AC(51)

Pharmacological Actions : Anti-Bacterial Agents : CK(970) : AC(316)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Andrographis has antioxidant, antioedema and analgesic activities.

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Pubmed Data : Phytother Res. 2009 Jul;23(7):958-64. PMID: 19142986

Article Published Date : Jul 01, 2009

Study Type : Animal Study

Additional Links

Substances : Andrographis : CK(81) : AC(35)

Pharmacological Actions : Analgesics : CK(372) : AC(78), Anti-edemic : CK(12) : AC(2), Antioxidants : CK(3653) : AC(1318)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Andrographis has immunomodulatory activity.

Click here to read the entire abstract

Pubmed Data : Planta Med. 2009 Jun;75(8):785-91. Epub 2009 Mar 4. PMID: 19263340

Article Published Date : Jun 01, 2009

Study Type : Animal Study

Additional Links

Substances : Andrographis : CK(81) : AC(35)

Diseases : Immune Disorders: Low Immune Function : CK(488) : AC(115)

Pharmacological Actions : Immunomodulatory : CK(536) : AC(142)

Andrographis may be more effective an anticancer agent than Doxorubicin in lymphoma.

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Pubmed Data : Mol Biol Rep. 2008 Dec;35(4):535-40. Epub 2007 Sep 5. PMID: 17805989

Article Published Date : Dec 01, 2008

Study Type : Animal Study

Additional Links

Substances : Andrographis : CK(81) : AC(35)

Diseases : Lymph Node Cancer : CK(4) : AC(2), Lymphoma : CK(209) : AC(69)

Pharmacological Actions : Anticarcinogenic Agents : CK(521) : AC(275), Antioxidants : CK(3653) : AC(1318)

Additional Keywords : Drug: Doxorubicin : CK(141) : AC(55), Plant Extracts : CK(3572) : AC(1216), Superiority of Natural Substances versus Drugs : CK(826) : AC(164)

Andrographolide, a compound found within andrographis, has anti-tumor activity in chemically-induced liver damage.

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Pubmed Data : Nutrition. 2005 Jun;21(6):756-61. PMID: 19679627

Article Published Date : Jun 01, 2005

Study Type : Animal Study

Additional Links

Substances : Andrographis : CK(81) : AC(35)

Diseases : Chemically-Induced Liver Damage : CK(475) : AC(175), Liver Cancer : CK(1641) : AC(266), Pesticide Toxicity : CK(147) : AC(45)

Pharmacological Actions : Hepatoprotective : CK(557) : AC(272)

Compounds found within Andrographis have potent anti-influenza activity against H1N1 and Avian Flu.

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Pubmed Data : Biol Pharm Bull. 2009;32(8):1385-1391. PMID: 19652378

Article Published Date : Jan 01, 2009

Study Type : Animal Study

Additional Links

Substances : Andrographis : CK(81) : AC(35)

Diseases : Avian Influenza : CK(23) : AC(11), H1N1 Infection : CK(467) : AC(87), Influenza A : CK(305) : AC(73)

Pharmacological Actions : Viral Hemagglutinin Inhibitor : CK(17) : AC(13)

Additional Keywords : Viral Hemmagglutinin Blocker : CK(3) : AC(2)

"The natural products parthenolide and andrographolide exhibit anti-cancer stem cell activity in multiple myeloma."

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Pubmed Data : Leuk Lymphoma. 2011 Jun ;52(6):1085-97. Epub 2011 Mar 21. PMID: 21417826

Article Published Date : Jun 01, 2011

Study Type : In Vitro Study

Additional Links

Substances : Andrographis : CK(81) : AC(35), Feverfew : CK(41) : AC(21)

Diseases : Cancer Stem Cells : CK(988) : AC(42), Multiple Myeloma : CK(156) : AC(53)

Pharmacological Actions : Antineoplastic Agents : CK(877) : AC(496), Antiproliferative : CK(1052) : AC(775), Apoptotic : CK(1489) : AC(1114), NF-kappaB Inhibitor : CK(595) : AC(401)

Additional Keywords : Cancer Stem Cells : CK(30) : AC(24), Plant Extracts : CK(3572) : AC(1216)

Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) : CK(1383) : AC(115)

Andrographis contains a compound known as andrographolide which exhibits anticancer and immunomodulatory activities.

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Pubmed Data : J Exp Ther Oncol. 2003 May-Jun;3(3):147-58. PMID: 14641821

Article Published Date : May 01, 2003

Study Type : In Vitro Study

Additional Links

Substances : Andrographis : CK(81) : AC(35)

Diseases : Cancers: All : CK(9062) : AC(2869)

Pharmacological Actions : Cell cycle arrest : CK(390) : AC(319), Immunomodulatory : CK(536) : AC(142), Tumor Necrosis Factor (TNF) Alpha Enhancer : CK(28) : AC(8)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Andrographis contains a compound which enhances chemosensitivity of cancer cells to doxorubicin.

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Pubmed Data : Biochem Pharmacol. 2010 May 1;79(9):1242-50. Epub 2009 Dec 21. PMID: 20026083

Article Published Date : May 01, 2010

Study Type : In Vitro Study

Additional Links

Substances : Andrographis : CK(81) : AC(35)

Diseases : Cancers: All : CK(9062) : AC(2869)

Pharmacological Actions : Apoptotic : CK(1489) : AC(1114), Chemosensitizer : CK(197) : AC(159)

Additional Keywords : Drug: Doxorubicin : CK(141) : AC(55), Drug-Plant-Vitamin Synergies : CK(1011) : AC(268)

Andrographis contains a compound which induces mitochondrial-mediated apoptosis in lymphoma cells.

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Pubmed Data : Clin Cancer Res. 2010 Aug 26. Epub 2010 Aug 26. PMID: 20798229

Article Published Date : Aug 26, 2010

Study Type : In Vitro Study

Additional Links

Substances : Andrographis : CK(81) : AC(35)

Diseases : Follicular Lymphoma : CK(5) : AC(5), Lymphoma : CK(209) : AC(69), Non-Hodgkin's lymphoma: B Cell : CK(5) : AC(5)

Pharmacological Actions : Apoptotic : CK(1489) : AC(1114)

Andrographis contains a compound which inhibits human liver cancer cell growth.

Click here to read the entire abstract

Pubmed Data : Planta Med. 2007 Oct;73(13):1397-401. Epub 2007 Oct 4. PMID: 17918040

Article Published Date : Oct 01, 2007

Study Type : In Vitro Study

Additional Links

Substances : Andrographis : CK(81) : AC(35)

Diseases : Liver Cancer : CK(1641) : AC(266)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Andrographis contains a compound which inhibits migration and invasion in human non-small lung cancer cells.

Click here to read the entire abstract

Pubmed Data : Eur J Pharmacol. 2010 Apr 25;632(1-3):23-32. Epub 2010 Jan 25. PMID: 20097193

Article Published Date : Apr 25, 2010

Study Type : In Vitro Study

Additional Links

Substances : Andrographis : CK(81) : AC(35)

Diseases : Cancer Metastasis : CK(272) : AC(135), Carcinoma: Non-Small-Cell Lung : CK(19) : AC(11), Lung Cancer : CK(496) : AC(198)

Pharmacological Actions : Anti-metastatic : CK(192) : AC(115), Antineoplastic Agents : CK(877) : AC(496)

Andrographis contains a compound which may induce cancer cell death through epidermal factor receptor and transferrin receptor modulation.

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Pubmed Data : Br J Pharmacol. 2010 Apr;159(7):1497-510. Epub 2010 Feb 19. PMID: 20233216

Article Published Date : Apr 01, 2010

Study Type : In Vitro Study

Additional Links

Substances : Andrographis : CK(81) : AC(35)

Diseases : Skin Cancer: Squamous Cell : CK(52) : AC(16)

Pharmacological Actions : Epidermal growth factor receptor (EGFR) inhibitor : CK(27) : AC(22)

Andrographis contains compounds which have antiprotozoal activity.

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Pubmed Data : Phytother Res. 2009 Jan;23(1):126-8. PMID: 18683849

Article Published Date : Jan 01, 2009

Study Type : In Vitro Study

Additional Links

Substances : Andrographis : CK(81) : AC(35)

Diseases : Protozoan Infections : CK(4) : AC(4)

Pharmacological Actions : Antiprotozoal Agents : CK(14) : AC(5)

Additional Keywords : Xanthones : CK(50) : AC(28)

Andrographis containsa compound which exhibits anti-invasive activity against colon cancer cells.

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Pubmed Data : Planta Med. 2010 Jun 10. Epub 2010 Jun 10. PMID: 20539971

Article Published Date : Jun 10, 2010

Study Type : In Vitro Study

Additional Links

Substances : Andrographis : CK(81) : AC(35)

Diseases : Cancer Metastasis : CK(272) : AC(135), Colon Cancer : CK(895) : AC(233)

Pharmacological Actions : Anti-metastatic : CK(192) : AC(115)

Andrographis exhibits insulin-releasing cells in vitro.

Click here to read the entire abstract

Pubmed Data : Acta Med Indones. 2008 Apr-Jun;40(2):63-8. PMID: 18560025

Article Published Date : Apr 01, 2008

Study Type : In Vitro Study

Additional Links

Substances : Andrographis : CK(81) : AC(35)

Diseases : Diabetes Mellitus: Type 1 : CK(1107) : AC(218)

Pharmacological Actions : Insulin-releasing : CK(26) : AC(15)

Andrographis has anti-inflammatory and anti-allergic activity.

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 2010 May 27;129(2):203-7. Epub 2010 Mar 20. PMID: 20307638

Article Published Date : May 27, 2010

Study Type : In Vitro Study

Additional Links

Substances : Andrographis : CK(81) : AC(35)

Diseases : Allergies : CK(502) : AC(92), Inflammation : CK(1077) : AC(363), Lipopolysaccharide-Induced Toxicity : CK(227) : AC(128)

Pharmacological Actions : Anti-Inflammatory Agents : CK(1230) : AC(433), Leukotriene Antagonists : CK(38) : AC(9), Prostaglandin Antagonists : CK(27) : AC(13), Thromboxane (TXB) Inhibitors : CK(5) : AC(4)

Andrographis inhibits cell cycle progression of human colorectal carcinoma cells

Click here to read the entire abstract

Pubmed Data : Chem Biol Interact. 2008 Aug 11;174(3):201-10. Epub 2008 Jun 20. PMID: 18619950

Article Published Date : Aug 11, 2008

Study Type : In Vitro Study

Additional Links

Substances : Andrographis : CK(81) : AC(35)

Diseases : Colon Cancer : CK(895) : AC(233), Colorectal Cancer : CK(877) : AC(321), Rectal Cancer : CK(1) : AC(1)

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