Apples

Apples

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View the Evidence: Substances

A combination of apple pectin and chamomile shortens the course of unspecific diarrhea in children.

Pubmed Data : Arzneimittelforschung. 2006;56(6):387-93. PMID: 16889120
Article Published Date : Jan 01, 2006
Study Type : Human Study
Additional Links
Substances : Apple Pectin : CK(55) : AC(13), Chamomile : CK(95) : AC(18)
Diseases : Diarrhea : CK(544) : AC(72)

Apple pectin reduced Cesium-137 levels by 62.6% in "Chenobyl" children.

Pubmed Data : Swiss Med Wkly. 2004 Jan 10;134(1-2):24-7. PMID: 14745664
Article Published Date : Jan 10, 2004
Study Type : Human Study
Additional Links
Substances : Apple Pectin : CK(55) : AC(13)
Diseases : Radiation-Induced Illness: Cesium-137 Exposure : CK(96) : AC(25)
Pharmacological Actions : Radioprotective : CK(458) : AC(183)

Apple pectin reduces the body burden of Cesium-137 in "Chernobyl" children.

Pubmed Data : Mol Cell Biochem. 1990 Jun 1;95(1):21-30. PMID: 17314090
Article Published Date : Jun 01, 1990
Study Type : Human Study
Additional Links
Substances : Apple Pectin : CK(55) : AC(13)
Diseases : Radiation-Induced Illness: Cesium-137 Exposure : CK(96) : AC(25)
Pharmacological Actions : Detoxifier : CK(306) : AC(101), Detoxifier: Radionuclide Removal : CK(23) : AC(4)

Apple pectin significantly reduces Cesium-137 load within 16 days in children exposed to radioisotopes as a result of Chernobyl.

Pubmed Data : Swiss Med Wkly. 2004 Dec 18;134(49-50):725-9. PMID: 15635491
Article Published Date : Dec 18, 2004
Study Type : Human Study
Additional Links
Substances : Apple Pectin : CK(55) : AC(13)
Diseases : Cardiovascular Diseases : CK(5138) : AC(641), Radiation-Induced Illness: Cesium-137 Exposure : CK(96) : AC(25)
Pharmacological Actions : Detoxifier : CK(306) : AC(101), Detoxifier: Radionuclide Removal : CK(23) : AC(4), Radioprotective : CK(458) : AC(183)

Apple peel extract inhibits the growth of Helicobacter pylori, and attenuates damage to the gastric mucosa caused by neutrophils.

Pubmed Data : J Agric Food Chem. 2009 Sep 9;57(17):7743-9. PMID: 19691323
Article Published Date : Sep 09, 2009
Study Type : Human Study
Additional Links
Substances : Apples : CK(179) : AC(57), Flavonoids : CK(909) : AC(289), Polyphenols : CK(427) : AC(174)
Diseases : Helicobacter Pylori Infection : CK(305) : AC(61)
Additional Keywords : Plant Extracts : CK(3616) : AC(1226), Proanthocyanidins : CK(159) : AC(46)

The consumption of apples is inversely associated with the risk of developing various cancers.

Pubmed Data : Ann Oncol. 2005 Nov;16(11):1841-4. Epub 2005 Aug 9. PMID: 16091428
Article Published Date : Nov 01, 2005
Study Type : Human Study
Additional Links
Substances : Apples : CK(179) : AC(57)
Diseases : Cancers: All : CK(9062) : AC(2869)

The consumption of apples is inversely related to the risk of colorectal cancer.

Pubmed Data : Rev Environ Health. 2009 Jan-Mar;24(1):59-74. PMID: 19476292
Article Published Date : Jan 01, 2009
Study Type : Human Study
Additional Links
Substances : Apples : CK(179) : AC(57)
Diseases : Colon Cancer : CK(895) : AC(233), Colorectal Cancer : CK(877) : AC(321)

The consumption of fruit, such as pear and apple, contribute to weight loss.

Pubmed Data : Nutrition. 2003 Mar;19(3):253-6. PMID: 12620529
Article Published Date : Mar 01, 2003
Study Type : Human Study
Additional Links
Substances : Apples : CK(179) : AC(57), Fruit: All : CK(1836) : AC(472), Pear : CK(16) : AC(5)
Diseases : Overweight : CK(2176) : AC(342)

The regular consumption of apples reduces colorectal cancer risk.

Pubmed Data : Basic Clin Pharmacol Toxicol. 2009 Mar;104(3):262-71. Epub 2009 Jan 20. PMID: 19926998
Article Published Date : Mar 01, 2009
Study Type : Human Study
Additional Links
Substances : Apples : CK(179) : AC(57)
Diseases : Colorectal Cancer : CK(877) : AC(321)
Pharmacological Actions : Chemopreventive : CK(1528) : AC(382)
Additional Keywords : Risk Reduction : CK(1909) : AC(196)

Total vegetable intake, total fruit intake, and lettuce, apple, and banana consumption is associated with a reduced risk for colorectal cancer.

Pubmed Data : Nutr Cancer. 1996;25(3):297-304. PMID: 8771572
Article Published Date : Jan 01, 1996
Study Type : Human Study
Additional Links
Substances : Apples : CK(179) : AC(57), Banana : CK(123) : AC(36), Fruit: All : CK(1836) : AC(472), Lettuce : CK(13) : AC(3), Vegetables: All : CK(551) : AC(69)
Diseases : Colon Cancer : CK(895) : AC(233), Colorectal Cancer : CK(877) : AC(321)
Pharmacological Actions : Chemopreventive : CK(1528) : AC(382)

A drug named "Medetopect" consisting of apple pectins, vitamin C and calcium phosphate reduces absorption of Plutonium-239 and Americium-241 from the gastrointestinal tract of animals.

Pubmed Data : Radiats Biol Radioecol. 1998 Jan-Feb;38(1):35-41. PMID: 9606404
Article Published Date : Jan 01, 1998
Study Type : Animal Study
Additional Links
Substances : Apple Pectin : CK(55) : AC(13), Calcium : CK(232) : AC(35), Vitamin C : CK(1274) : AC(238)
Diseases : Radiation Induced Illness : CK(1018) : AC(249), Radiation-Induced Illness: Americium : CK(4) : AC(2), Radiation-Induced Illness: Plutonium : CK(15) : AC(8)
Pharmacological Actions : Radioprotective : CK(458) : AC(183)

A novel form of apple pectin improves the lipid profile, insulin resistance and other cardiometabolic risk factors in diabetic rats.

Pubmed Data : J Agric Food Chem. 2008 May 28;56(10):3574-81. Epub 2008 Apr 23. PMID: 18433105
Article Published Date : May 28, 2008
Study Type : Animal Study
Additional Links
Substances : Apple Pectin : CK(55) : AC(13)
Diseases : Insulin Resistance : CK(1034) : AC(221)

Apple and pear peel have significant positive influence on plasma lipid levels and antioxidant capacity in rats.

Pubmed Data : J Agric Food Chem. 2003 Sep 10;51(19):5780-5. PMID: 12952433
Article Published Date : Sep 10, 2003
Study Type : Animal Study
Additional Links
Substances : Apples : CK(179) : AC(57), Pear : CK(16) : AC(5)
Diseases : Hyperlipidemia : CK(1211) : AC(109), Oxidative Stress : CK(1945) : AC(710)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Hypolipidemic : CK(370) : AC(80)

Apple cider vinegar contains an antitumor agent in experimental mouse tumors.

Pubmed Data : Biosci Biotechnol Biochem. 2007 Sep;71(9):2124-9. Epub 2007 Sep 7. PMID: 17827702
Article Published Date : Sep 01, 2007
Study Type : Animal Study
Additional Links
Substances : Apple Cider Vinegar : CK(4) : AC(2)
Diseases : Tumors : CK(197) : AC(110)
Additional Keywords : Alpha-Glycan : CK(2) : AC(1)

Apple cider vinegars, regardless of the production method, decreased triglyceride and VLDL levels in all groups when compared to animals on high-cholesterol diets without vinegar supplementation. Apple cider vinegars increased total cholesterol and HDL an

Pubmed Data : . PMID: 21561165
Article Published Date : Jun 21, 2011
Study Type : Animal Study
Additional Links
Substances : Apple Cider Vinegar : CK(4) : AC(2)
Diseases : High Cholesterol: very low density lipoprotein (VLDL) : CK(24) : AC(9), Hyperlipidemia : CK(1211) : AC(109), Triglycerides: Elevated : CK(340) : AC(65)
Pharmacological Actions : Hypolipidemic : CK(370) : AC(80)

Apple fibers and polyphenols may play a role in preventing atherosclerosis by decreasing uric acid plasma level.

Pubmed Data : Phytomedicine. 2007 Apr;14(4):280-4. Epub 2007 Feb 12. PMID: 18558693
Article Published Date : Apr 01, 2007
Study Type : Animal Study
Additional Links
Substances : Apples : CK(179) : AC(57), Fiber : CK(484) : AC(70), Flavonoids : CK(909) : AC(289), Polyphenols : CK(427) : AC(174)
Diseases : Atherosclerosis : CK(523) : AC(77), Hyperuricemia : CK(253) : AC(32)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)
Additional Keywords : Plant Extracts : CK(3616) : AC(1226)

Apple juice can effectively prevent the progress of atherosclerosis.

Pubmed Data : Lipids Health Dis. 2009;8:39. Epub 2009 Oct 5. PMID: 19804641
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Substances : Apples : CK(179) : AC(57)
Diseases : Atherosclerosis : CK(523) : AC(77), C-Reactive Protein : CK(819) : AC(74), Fibrinogen: Elevated : CK(114) : AC(13)

Apple juice concentrate prevents oxidative damage and impaired maze performance in aged mice.

Pubmed Data : Ann Clin Psychiatry. 2009 Jul-Sep;21(3):148-61. PMID: 16340085
Article Published Date : Jul 01, 2009
Study Type : Animal Study
Additional Links
Substances : Apples : CK(179) : AC(57)
Diseases : Aging: Brain : CK(1747) : AC(68), Cognitive Decline/Dysfunction : CK(522) : AC(87)
Pharmacological Actions : Neuroprotective Agents : CK(962) : AC(480)

Apple juice upregulates antioxidant-associated genes in the rat colon and liver, which may account for apple's anti-cancer activity.

Pubmed Data : Carcinogenesis. 2000 Aug;21(8):1461-7. PMID: 20652274
Article Published Date : Aug 01, 2000
Study Type : Animal Study
Additional Links
Substances : Apples : CK(179) : AC(57), Polyphenols : CK(427) : AC(174)
Diseases : Colon Cancer : CK(895) : AC(233), Liver Cancer : CK(1641) : AC(266)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Chemopreventive : CK(1528) : AC(382)

Apple leaves contain compounds which may have therapeutic value against advanced glycation end-productions and vasoconstriction.

Pubmed Data : Phytochemistry. 2009 Dec 18. Epub 2009 Dec 18. PMID: 20022617
Article Published Date : Dec 18, 2009
Study Type : Animal Study
Additional Links
Substances : Apples : CK(179) : AC(57)
Diseases : Advanced Glycation End products (AGE) : CK(2114) : AC(40)
Pharmacological Actions : Anti-Inflammatory Agents : CK(1230) : AC(433), Vasodilator Agents : CK(262) : AC(54)

Apple pectin and Bifidobacterium longum inhibit colorectal tumors in transgenic mice.

Pubmed Data : Exp Anim. 2000 Oct;49(4):305-7. PMID: 11109558
Article Published Date : Oct 01, 2000
Study Type : Transgenic Animal Study
Additional Links
Substances : Apple Pectin : CK(55) : AC(13), Bifidobacterium : CK(476) : AC(40), Bifidobacterium Longum : CK(66) : AC(8)
Diseases : Colon Cancer : CK(895) : AC(233), Colorectal Cancer : CK(877) : AC(321), Colorectal Tumors : CK(5) : AC(4)

Apple pectin and Lactobacillus casei inhibit liver cancer metastasis.

Pubmed Data : Hum Cell. 1999 Dec;12(4):189-96. PMID: 10834105
Article Published Date : Dec 01, 1999
Study Type : Animal Study
Additional Links
Substances : Apple Pectin : CK(55) : AC(13), Lactobacillus casei : CK(151) : AC(26)
Diseases : Cancer Metastasis : CK(272) : AC(135), Liver Cancer : CK(1641) : AC(266)

Apple pectin decrease the number and incidence of colon cancer.

Pubmed Data : J Exp Clin Cancer Res. 1997 Mar;16(1):33-8. PMID: 9148858
Article Published Date : Mar 01, 1997
Study Type : Animal Study
Additional Links
Substances : Apple Pectin : CK(55) : AC(13)
Diseases : Colon Cancer : CK(895) : AC(233)
Additional Keywords : Bacteriostatic : CK(2) : AC(1)

Apple pectin enhances the absorption of quercetin, probably due to its improvement of the absorptive capacity of the small intestine.

Pubmed Data : Cancer Sci. 2009 May 12. PMID: 19292474
Article Published Date : May 12, 2009
Study Type : Animal Study
Additional Links
Substances : Apple Pectin : CK(55) : AC(13)
Diseases : Malabsorption Syndrome : CK(34) : AC(11)

Apple polyphenol may reduce the adverse effects of the immunization adjuvant cholera toxin.

Pubmed Data : Vaccine. 2009 Jul 30;27(35):4808-17. Epub 2009 Jun 17. PMID: 19539583
Article Published Date : Jul 30, 2009
Study Type : Animal Study
Additional Links
Substances : Apple Polyphenols : CK(4) : AC(2), Apples : CK(179) : AC(57), Polyphenols : CK(427) : AC(174)
Diseases : Cholera : CK(27) : AC(17), Vaccine-induced Toxicity : CK(1130) : AC(163)
Additional Keywords : Drug Side Effect Attenuation : CK(252) : AC(49)

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