Ashwagandha

Ashwagandha

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- 63
Quick Summary: 62 associated Diseases
NameCumulative KnowledgeArticle CountFocus Articles
Oxidative Stress133Log in | Sign up
Alcohol Withdrawal122Log in | Sign up
Fatigue101Log in | Sign up
Insomnia101Log in | Sign up
Cancers: All55Log in | Sign up
Alzheimer's Disease42Log in | Sign up
Hypothyroidism42Log in | Sign up
Immune Disorders: Low Immune Function42Log in | Sign up
Skin Cancer42Log in | Sign up
Breast Cancer32Log in | Sign up
Gout32Log in | Sign up
Leukemia33Log in | Sign up
Advanced Glycation End products (AGE)21Log in | Sign up
Advanced Glycation Endproduct (AGE) Formation21Log in | Sign up
Anxiety Disorders21Log in | Sign up
Arthritis21Log in | Sign up
Aspergillosis21Log in | Sign up
Cholesterol: High21Log in | Sign up
Cognitive Decline/Dysfunction21Log in | Sign up
Dalton's Ascitic Lymphoma21Log in | Sign up
Dementia22Log in | Sign up
Diabetes Mellitus: Type 221Log in | Sign up
Diabetes: Glycation/A1C21Log in | Sign up
Duchenne's Muscular Dystrophy21Log in | Sign up
Heart Attack21Log in | Sign up
Heart Failure21Log in | Sign up
Hypertension21Log in | Sign up
Hypertension: Pulmonary21Log in | Sign up
Hypothyroidism: metformin-induced21Log in | Sign up
Infertility: Male21Log in | Sign up
Insulin Resistance21Log in | Sign up
Iron Overload21Log in | Sign up
Lead Poisoning21Log in | Sign up
Listeria Infections21Log in | Sign up
Lupus Erythematosus: Systemic21Log in | Sign up
Lymphoma21Log in | Sign up
Malaria21Log in | Sign up
Morphine Tolerance/Dependence21Log in | Sign up
Myocardial Infarction21Log in | Sign up
Myocardial Ischemia21Log in | Sign up
Neurodegenerative Diseases22Log in | Sign up
Neutropenia: Chemotherapy Induced21Log in | Sign up
Opiate Tolerance21Log in | Sign up
Oral Cancer21Log in | Sign up
Osteoporosis21Log in | Sign up
Over-active Libido21Log in | Sign up
Pancreatic Cancer21Log in | Sign up
Parkinson Disease21Log in | Sign up
Pesticide Toxicity 21Log in | Sign up
Salmonella Infections21Log in | Sign up
Vaccine-induced Toxicity 21Log in | Sign up
Acute Myeloid Leukemia11Log in | Sign up
Aging11Log in | Sign up
Chronic Myeloid Leukemia11Log in | Sign up
Hyperuricemia11Log in | Sign up
Intima Media Thickening 11Log in | Sign up
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View the Evidence: Substances

A multi-herbal product called Protandim has significant antioxidant properties in human subjects.

Pubmed Data : Arzneimittelforschung. 2006;56(6):387-93. PMID: 16413416
Article Published Date : Jan 01, 2006
Study Type : Human Study
Additional Links
Substances : Ashwagandha : CK(137) : AC(63), Bacopa : CK(47) : AC(18), Green Tea : CK(952) : AC(283), Milk Thistle : CK(226) : AC(55), Protandim : CK(20) : AC(7), Turmeric : CK(2969) : AC(1565)
Diseases : Oxidative Stress : CK(1867) : AC(710)
Pharmacological Actions : Antioxidants : CK(3503) : AC(1292), Catalase Up-Regulation : CK(22) : AC(8), Superoxide Dismutase Up-regulation : CK(127) : AC(40)

Ashwaganda attenuates withdrawal-induced anxiety due to chronic ethanol consumption.

Pubmed Data : Indian J Exp Biol. 2008 Jun;46(6):470-5. PMID: 18697607
Article Published Date : Jun 01, 2008
Study Type : Human Study
Additional Links
Substances : Ashwagandha : CK(137) : AC(63)
Diseases : Alcohol Withdrawal : CK(54) : AC(11)

Ashwaganda has significant blood sugar lowering, diuretic and cholesterol lowering effects.

Pubmed Data : Indian J Exp Biol. 2000 Jun;38(6):607-9. PMID: 11116534
Article Published Date : Jun 01, 2000
Study Type : Human Study
Additional Links
Substances : Ashwagandha : CK(137) : AC(63)

A multi-herbal product called Protandim exhibits chemopreventive properties in a mouse model of skin cancer.

Pubmed Data : PLoS One. 2010;5(7):e11902. Epub 2010 Jul 30. PMID: 20689586
Article Published Date : Jan 01, 2010
Study Type : Animal Study
Additional Links
Substances : Ashwagandha : CK(137) : AC(63), Bacopa : CK(47) : AC(18), Green Tea : CK(952) : AC(283), Milk Thistle : CK(226) : AC(55), Protandim : CK(20) : AC(7), Turmeric : CK(2969) : AC(1565)
Diseases : Skin Cancer : CK(438) : AC(171)
Pharmacological Actions : Apoptotic : CK(1416) : AC(1089), Chemopreventive : CK(1314) : AC(355), Superoxide Dismutase Up-regulation : CK(127) : AC(40), Tumor Suppressor Protein p53 Upregulation : CK(140) : AC(103)

A multi-herbal product called Protandim has chemopreventive properties against skin cancer.

Pubmed Data : PLoS One. 2009;4(4):e5284. Epub 2009 Apr 22. PMID: 19384424
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Substances : Ashwagandha : CK(137) : AC(63), Bacopa : CK(47) : AC(18), Green Tea : CK(952) : AC(283), Milk Thistle : CK(226) : AC(55), Protandim : CK(20) : AC(7), Turmeric : CK(2969) : AC(1565)
Diseases : Oxidative Stress : CK(1867) : AC(710), Skin Cancer : CK(438) : AC(171)
Pharmacological Actions : Antioxidants : CK(3503) : AC(1292), NF-kappa-B-inducing kinase (NIK) modulator : CK(3) : AC(2), Superoxide Dismutase Up-regulation : CK(127) : AC(40), Tumor Suppressor Protein p53 Upregulation : CK(140) : AC(103), Vascular Cell Adhesion Molecule-1 Inhibitor : CK(94) : AC(24)

A multi-herbal product called Protandim prevents fibrosis and capillary loss and preserves right ventricular function in rats.

Pubmed Data : Circulation. 2009 Nov 17;120(20):1951-60. Epub 2009 Nov 2. PMID: 19884466
Article Published Date : Nov 17, 2009
Study Type : Animal Study
Additional Links
Substances : Ashwagandha : CK(137) : AC(63), Bacopa : CK(47) : AC(18), Green Tea : CK(952) : AC(283), Milk Thistle : CK(226) : AC(55), Protandim : CK(20) : AC(7), Turmeric : CK(2969) : AC(1565)
Diseases : Heart Failure : CK(669) : AC(97), Hypertension : CK(2615) : AC(260), Hypertension: Pulmonary : CK(1830) : AC(34)
Pharmacological Actions : Anti-Fibrotic : CK(30) : AC(19), Vascular Endothelial Growth Factor A Inhibitor : CK(102) : AC(58)

A poly-herbal formula named Protandim reduces oxidative stress in a mouse model of Duchenne muscular dystrophy.

Pubmed Data : J Diet Suppl. 2010 Jun 1;7(2):159-178. PMID: 20740052
Article Published Date : Jun 01, 2010
Study Type : Animal Study
Additional Links
Substances : Ashwagandha : CK(137) : AC(63), Bacopa : CK(47) : AC(18), Green Tea : CK(952) : AC(283), Milk Thistle : CK(226) : AC(55), Protandim : CK(20) : AC(7), Turmeric : CK(2969) : AC(1565)
Diseases : Duchenne's Muscular Dystrophy : CK(12) : AC(6)
Pharmacological Actions : Antioxidants : CK(3503) : AC(1292)

A polyherbal formula is comparable to the benzodiazepiene drug alprazolam in reducing ethanol withdrawal-induced anxiety behavior.

Pubmed Data : Evid Based Complement Alternat Med. 2011;2011. Epub 2010 Sep 7. PMID: 20953426
Article Published Date : Jan 01, 2011
Study Type : Animal Study
Additional Links
Substances : Ashwagandha : CK(137) : AC(63), Green Tea : CK(952) : AC(283), Holy Basil : CK(52) : AC(26), Shilajit : CK(20) : AC(7), Triphala : CK(11) : AC(7)
Diseases : Alcohol Withdrawal : CK(54) : AC(11), Anxiety Disorders : CK(641) : AC(82)
Additional Keywords : Benzodiazepine Alternatives : CK(26) : AC(4), Drug: Alprazolam : CK(2) : AC(2), Natural Substances Versus Drugs : CK(1043) : AC(159)

Ashwaganda (W. somnifera) increases host resistance through increasing production of colony-stimulating activity in Listeria infected mice.

Pubmed Data : Breast Cancer Res Treat. 2010 Feb 16. Epub 2010 Feb 16. PMID: 16919825
Article Published Date : Feb 16, 2010
Study Type : Animal Study
Additional Links
Substances : Ashwagandha : CK(137) : AC(63)
Diseases : Listeria Infections : CK(24) : AC(17)
Additional Keywords : Colony-Stimulating Factors (CSFs) : CK(33) : AC(9), Myeloid Progenitors : CK(8) : AC(4)

Ashwaganda ameliorates the oxidative damage associated with lead poisoning.

Pubmed Data : Hematol Oncol. 2009 Mar;27(1):17-22. PMID: 10816336
Article Published Date : Mar 01, 2009
Study Type : Animal Study
Additional Links
Substances : Ashwagandha : CK(137) : AC(63)
Diseases : Lead Poisoning : CK(173) : AC(34)

Ashwaganda and Bauhinia purpurea stimulate thyroid function.

Pubmed Data : J Ethnopharmacol. 1999 Nov 1;67(2):233-9. PMID: 10619390
Article Published Date : Nov 01, 1999
Study Type : Animal Study
Additional Links
Substances : Ashwagandha : CK(137) : AC(63), Bauhinia purpurea : CK(10) : AC(6)
Diseases : Hypothyroidism : CK(516) : AC(78)

Ashwaganda attenuates 6-hydroxydopamine induced Parkinsonism in rats.

Pubmed Data : Hum Exp Toxicol. 2005 Mar;24(3):137-47. PMID: 15901053
Article Published Date : Mar 01, 2005
Study Type : Animal Study
Additional Links
Substances : Ashwagandha : CK(137) : AC(63)
Diseases : Parkinson Disease : CK(541) : AC(79)

Ashwaganda attenuates cyclophosphamide-induced toxicity.

Pubmed Data : J Ethnopharmacol. 1998 Oct;62(3):209-14. PMID: 9849630
Article Published Date : Oct 01, 1998
Study Type : Animal Study
Additional Links
Substances : Ashwagandha : CK(137) : AC(63)

Ashwaganda attenuates insecticide-induced inhibition and impairment of cognitive function.

Pubmed Data : Int Immunopharmacol. 2003 Sep;3(9):1313-24. PMID: 20521626
Article Published Date : Sep 01, 2003
Study Type : Animal Study
Additional Links
Substances : Ashwagandha : CK(137) : AC(63)
Diseases : Cognitive Decline/Dysfunction : CK(514) : AC(87), Pesticide Toxicity : CK(147) : AC(44)
Pharmacological Actions : Neuroprotective Agents : CK(921) : AC(464)
Additional Keywords : Plant Extracts : CK(3401) : AC(1158)

Ashwaganda contains compounds which may amerliorate neuronal dysfunction in Alzheimer's disease.

Pubmed Data : Eur J Neurosci. 2006 Mar;23(6):1417-26. PMID: 16553605
Article Published Date : Mar 01, 2006
Study Type : Animal Study
Additional Links
Substances : Ashwagandha : CK(137) : AC(63)
Diseases : Alzheimer's Disease : CK(837) : AC(165)

Ashwaganda has significant cholesterol lowering and blood lipid modulating effects in the rat experimental model.

Pubmed Data : Caries Res. 2001 Mar-Apr;35(2):125-8. PMID: 16713218
Article Published Date : Mar 01, 2001
Study Type : Animal Study
Additional Links
Substances : Ashwagandha : CK(137) : AC(63)
Diseases : Cholesterol: High : CK(922) : AC(156)
Pharmacological Actions : Hypolipidemic : CK(380) : AC(80)

Ashwaganda has significant therapeutic effects against Dalton's Ascitic Lymphoma.

Pubmed Data : Exp Lung Res. 2000 Dec;26(8):709-30. PMID: 15234777
Article Published Date : Dec 01, 2000
Study Type : Animal Study
Additional Links
Substances : Ashwagandha : CK(137) : AC(63)
Diseases : Dalton's Ascitic Lymphoma : CK(2) : AC(1), Lymphoma : CK(225) : AC(68)

Ashwaganda has therapeutic properties in a pristane-induced model of systemic lupus erythematosus.

Pubmed Data : Inflammopharmacology. 2011 Dec 13. Epub 2011 Dec 13. PMID: 22160928
Article Published Date : Dec 13, 2011
Study Type : Animal Study
Additional Links
Substances : Ashwagandha : CK(137) : AC(63)
Diseases : Lupus Erythematosus: Systemic : CK(949) : AC(53)

Ashwaganda improves immune function by increasing Th1 (cell-mediated) immunity. - Article 2.

Pubmed Data : Life Sci. 2007 Mar 27;80(16):1525-38. Epub 2007 Jan 25. PMID: 17336338
Article Published Date : Mar 27, 2007
Study Type : Animal Study
Additional Links
Substances : Ashwagandha : CK(137) : AC(63)
Diseases : Immune Disorders: Low Immune Function : CK(488) : AC(115)
Additional Keywords : TH1 Immune Booster : CK(4) : AC(1)

Ashwaganda improves semen quality in stress-related male fertility.

Pubmed Data : Evid Based Complement Alternat Med. 2009 Sep 29. PMID: 19789214
Article Published Date : Sep 29, 2009
Study Type : Animal Study
Additional Links
Substances : Ashwagandha : CK(137) : AC(63)
Diseases : Infertility: Male : CK(201) : AC(53)

Ashwaganda interferes with sexual desire via hyperprolactinemic, GABAergic, serotonergic or sedative activities.

Pubmed Data : Asian J Androl. 2002 Dec;4(4):295-8. PMID: 12508132
Article Published Date : Dec 01, 2002
Study Type : Animal Study
Additional Links
Substances : Ashwagandha : CK(137) : AC(63)
Diseases : Over-active Libido : CK(2) : AC(1)
Additional Keywords : GABAergic : CK(2) : AC(1), Serotonergic : CK(2) : AC(1)

Ashwaganda markedly prevents bone changes in ovarectomized rats.

Pubmed Data : Phytomedicine. 2007 Feb;14(2-3):136-42. Epub 2006 May 18. PMID: 16597369
Article Published Date : Feb 01, 2007
Study Type : Animal Study
Additional Links
Substances : Ashwagandha : CK(137) : AC(63)
Diseases : Osteoporosis : CK(1090) : AC(205)

Ashwaganda may positively counterbalance the TH2 overstimulation induced by vaccination while supporting TH1 mediated immunity.

Pubmed Data : Vaccine. 2009 Jul 21. PMID: 19628058
Article Published Date : Jul 21, 2009
Study Type : Animal Study
Additional Links
Substances : Ashwagandha : CK(137) : AC(63)
Diseases : Vaccine-induced Toxicity : CK(1086) : AC(163)

Ashwaganda protects against systemic Aspergillus infection.

Pubmed Data : Immunopharmacol Immunotoxicol. 1998 Feb;20(1):191-8. PMID: 9543708
Article Published Date : Feb 01, 1998
Study Type : Animal Study
Additional Links
Substances : Ashwagandha : CK(137) : AC(63)
Diseases : Aspergillosis : CK(9) : AC(11)

Ashwaganda reduces morphine tolerance and dependence in mice

Pubmed Data : J Ethnopharmacol. 1997 Aug;57(3):213-7. PMID: 9292416
Article Published Date : Aug 01, 1997
Study Type : Animal Study
Additional Links
Substances : Ashwagandha : CK(137) : AC(63)
Diseases : Morphine Tolerance/Dependence : CK(104) : AC(17), Opiate Tolerance : CK(14) : AC(3)

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