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Biochanin A

Biochanin A

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Article Count - 8
Cumulative Knowledge - 9

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Quick Summary: Current access displays 2 out of 8 associated Diseases

Name	Cumulative Knowledge	Article Count	Focus Articles
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Cancers: Multi-Drug Resistant	2	2	Log in \| Sign up

Quick Summary: Current access displays 2 out of 9 associated Pharmacological Actions

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View the Evidence: Substances

Phytoestrogens can stimulate testosterone synthesis during puberty in male goats by increasing the secretion of T3; a hormone known to stimulate Leydig cell steroidogenesis.

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Pubmed Data : Acta Vet Scand. 2009 Dec 10;51:51. PMID: 20003293

Article Published Date : Dec 10, 2009

Study Type : Animal Study

Additional Links

Substances : Biochanin A : CK(9) : AC(8), Daidzein : CK(965) : AC(28), Formononetin : CK(2) : AC(1), Genistein : CK(450) : AC(174), phytoestrogens : CK(699) : AC(210)

Diseases : Hypothyroidism : CK(537) : AC(78), Low Testosterone : CK(385) : AC(70)

Pharmacological Actions : Secretagogue : CK(158) : AC(36), Steroidogenesis : CK(3) : AC(2)

Biochanin A selectively inhibits the growth of Clostridium.

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Pubmed Data : Molecules. 2010;15(3):1270-9. Epub 2010 Mar 3. PMID: 20335979

Article Published Date : Jan 01, 2010

Study Type : In Vitro Study

Additional Links

Substances : Biochanin A : CK(9) : AC(8)

Diseases : Clostridium Infections : CK(171) : AC(29)

Pharmacological Actions : Anti-Bacterial Agents : CK(970) : AC(316)

Flavanoid rich honey may act as chemosensitizers in multidrug resistant cancers.

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Pubmed Data : Med Hypotheses. 2011 Jan 17. Epub 2011 Jan 17. PMID: 21247706

Article Published Date : Jan 17, 2011

Study Type : In Vitro Study

Additional Links

Substances : Biochanin A : CK(9) : AC(8), Chrysin : CK(15) : AC(12), Flavonoids : CK(909) : AC(289), Genistein : CK(450) : AC(174), Honey : CK(251) : AC(50), Kaempferol : CK(27) : AC(22), Naringenin : CK(17) : AC(12), Quercetin : CK(318) : AC(136)

Diseases : Cancers: Multi-Drug Resistant : CK(92) : AC(73)

Pharmacological Actions : Chemosensitizer : CK(197) : AC(159)

Phytoestrogens-mediated induction of phase II detoxification enzymes may be responsible for their protective effect against estrogen-induced breast cancer.

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Pubmed Data : Biochem J. 2005 Jan 1;385(Pt 1):279-87. PMID: 15456407

Article Published Date : Jan 01, 2005

Study Type : In Vitro Study

Additional Links

Substances : Biochanin A : CK(9) : AC(8), Genistein : CK(450) : AC(174), Resveratrol : CK(977) : AC(590)

Diseases : Breast Cancer : CK(2354) : AC(621), DNA damage : CK(711) : AC(293), Estrogen Dominance : CK(106) : AC(37)

Pharmacological Actions : Phase II Detoxification Enzyme Inducer : CK(64) : AC(32)

Additional Keywords : Estrogen Receptor Beta : CK(24) : AC(11), Stilbenes : CK(402) : AC(242)

Red clover demonstrates aromatase inhibition activity, which may reduce the risk of estrogen receptor positive breast cancer.

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Pubmed Data : Br J Nutr. 2008 Feb;99(2):303-10. Epub 2007 Aug 29. PMID: 17761019

Article Published Date : Feb 01, 2008

Study Type : In Vitro Study

Additional Links

Substances : Biochanin A : CK(9) : AC(8), Red Clover : CK(36) : AC(9)

Diseases : Breast Cancer : CK(2354) : AC(621)

Pharmacological Actions : Aromatase Inhibitors : CK(33) : AC(23)

Seed germination of chickpeas (i.e. sprouting) increases the levels of four main isoflavones in chickpeas.

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Pubmed Data : J Liq Chromatogr Relat Technol. 2009 Jan 1;32(19):2879-2892. PMID: 20046900

Article Published Date : Jan 01, 2009

Study Type : In Vitro Study

Additional Links

Substances : Biochanin A : CK(9) : AC(8), Chickpea : CK(32) : AC(9), Isoflavones : CK(627) : AC(124), Sprouts : CK(76) : AC(36)

The isoflavones biochanin A and genistein inhibit the cell growth of stomach cancer lines by inducing programmed cell death.

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Pubmed Data : Cancer Res. 1993 Dec 1;53(23):5815-21. PMID: 8242641

Article Published Date : Dec 01, 1993

Study Type : In Vitro Study

Additional Links

Substances : Biochanin A : CK(9) : AC(8), Genistein : CK(450) : AC(174), Isoflavones : CK(627) : AC(124)

Diseases : Stomach Cancer : CK(373) : AC(20)

Pharmacological Actions : Apoptotic : CK(1489) : AC(1114)

The isoflavones biochanin A, daidzein and especially genistein inhibit the growth of breast cancer cells, including those expressing the multi-drug resistance gene.

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Pubmed Data : Biochem Biophys Res Commun. 1991 Aug 30;179(1):661-7. PMID: 1883387

Article Published Date : Aug 30, 1991

Study Type : In Vitro Study

Additional Links

Substances : Biochanin A : CK(9) : AC(8), Daidzein : CK(965) : AC(28), Genistein : CK(450) : AC(174), Isoflavones : CK(627) : AC(124)

Diseases : Breast Cancer : CK(2354) : AC(621), Cancers: Multi-Drug Resistant : CK(92) : AC(73)

Pharmacological Actions : Antineoplastic Agents : CK(877) : AC(496), Antiproliferative : CK(1052) : AC(775)

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