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Bitter Melon
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Additional Topics Details for this Page
Article Count
- 18
Cumulative Knowledge
- 55
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Quick Summary: Current access displays 2 out of 17 associated Diseases
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View the Evidence: Substances
Bitter melon appears to have therapeutic activity in the treatment of HIV infection.
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2009 May 23. PMID:
12346831
Article Published Date
: May 23, 2009
Study Type
: Human Study
Additional Links
Substances
:
Bitter Melon : CK(65) : AC(18)
Diseases
:
HIV Infections : CK(577) : AC(184)
Pharmacological Actions
:
Anti-HIV Agents : CK(108) : AC(60)
Bitter melon contains compounds with anti-HIV activity.
Click here to read the entire abstract
Pubmed Data
: Thyroid. 2000 Aug;10(8):659-63. PMID:
7665070
Article Published Date
: Aug 01, 2000
Study Type
: Human Study
Additional Links
Substances
:
Bitter Melon : CK(65) : AC(18)
Diseases
:
HIV Infections : CK(577) : AC(184)
Pharmacological Actions
:
Antiviral Agents : CK(613) : AC(280)
Bitter melon is superior to the drug rosiglitazone (Avandia) in type 2 diabetic patients.
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2009 May;16(5):401-5. Epub 2009 Apr 10. PMID:
19362455
Article Published Date
: May 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Bitter Melon : CK(65) : AC(18)
Diseases
:
Diabetes Mellitus: Type 2 : CK(3429) : AC(341)
Additional Keywords
:
Food as Medicine : CK(18) : AC(6)
,
Hall of Fame : CK(35) : AC(5)
,
Superiority of Natural Substances versus Drugs : CK(826) : AC(164)
Bitter gourd (Momordica charantia) stimulates beta cell regeneration in diabetic rats.
Click here to read the entire abstract
Pubmed Data
: Indian J Exp Biol. 2007 Dec;45(12):1055-62. PMID:
18254212
Article Published Date
: Dec 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Bitter Melon : CK(65) : AC(18)
Diseases
:
Diabetes Mellitus: Type 1 : CK(1107) : AC(218)
Additional Keywords
:
Beta Cell Regeneration : CK(60) : AC(24)
Bitter melon (M. charantia) may have a therapeutic role in conditions involving elevated ammonia levels.
Click here to read the entire abstract
Pubmed Data
: Evid Based Complement Alternat Med. 2010 Jan 4. Epub 2010 Jan 4. PMID:
20047891
Article Published Date
: Jan 04, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Bitter Melon : CK(65) : AC(18)
Diseases
:
Ammonia: Elevated : CK(89) : AC(17)
Bitter melon (Momordica charantia) and Phyllanthus urinaria have hypoglyemic properties.
Click here to read the entire abstract
Pubmed Data
: Nippon Yakurigaku Zasshi. 1992 Nov;100(5):415-21. PMID:
1464400
Article Published Date
: Nov 01, 1992
Study Type
: Animal Study
Additional Links
Substances
:
Bitter Melon : CK(65) : AC(18)
,
Phyllanthus urinaria : CK(37) : AC(21)
Diseases
:
Diabetes Mellitus: Type 1 : CK(1107) : AC(218)
Pharmacological Actions
:
Hypoglycemic Agents : CK(563) : AC(156)
Additional Keywords
:
Brazilian Traditional Medicine : CK(8) : AC(4)
Bitter melon attenuates fructose-induced insulin resistance in fructose-fed rats.
Click here to read the entire abstract
Pubmed Data
: Antioxid Redox Signal. 2005 Nov-Dec;7(11-12):1612-20. PMID:
19429344
Article Published Date
: Nov 01, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Bitter Melon : CK(65) : AC(18)
Diseases
:
Adiponectin: Low Levels : CK(88) : AC(25)
,
Fructose-Induced Toxicity : CK(138) : AC(49)
,
Insulin Resistance : CK(1034) : AC(221)
Additional Keywords
:
Plant Extracts : CK(3572) : AC(1216)
Bitter melon demonstrates anti-tumor activity.
Click here to read the entire abstract
Pubmed Data
: Cancer Res. 1983 Nov;43(11):5151-5. PMID:
6616452
Article Published Date
: Nov 01, 1983
Study Type
: Animal Study
Additional Links
Substances
:
Bitter Melon : CK(65) : AC(18)
Diseases
:
Tumors : CK(197) : AC(110)
Bitter melon has a preventive efffect on abdominal and liver fat in high-fat-fed hamster.
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2009 Jul 22;57(14):6461-7. PMID:
19601676
Article Published Date
: Jul 22, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Bitter Melon : CK(65) : AC(18)
Diseases
:
Abdominal Obesity (Midsection Fat) : CK(348) : AC(53)
,
Fatty Liver : CK(493) : AC(122)
,
Obesity : CK(1849) : AC(275)
Additional Keywords
:
Plant Extracts : CK(3572) : AC(1216)
Bitter melon has anti-ulcer properties.
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2009 Jun 25;123(3):464-9. Epub 2009 Mar 26. PMID:
19501279
Article Published Date
: Jun 25, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Bitter Melon : CK(65) : AC(18)
Diseases
:
Duodenal Ulcer : CK(89) : AC(26)
,
Gastric Ulcer : CK(246) : AC(91)
Pharmacological Actions
:
Anti-Ulcer Agents : CK(162) : AC(57)
Additional Keywords
:
Plant Extracts : CK(3572) : AC(1216)
Bitter melon has significant effect against insulin resistance and visceral obesity of mice on a high-fat diet.
Click here to read the entire abstract
Pubmed Data
: Diabetes Res Clin Pract. 2008 Aug;81(2):134-43. Epub 2008 Jun 11. PMID:
18550200
Article Published Date
: Aug 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Bitter Melon : CK(65) : AC(18)
Diseases
:
Abdominal Obesity (Midsection Fat) : CK(348) : AC(53)
,
Diabetes Mellitus: Type 2 : CK(3429) : AC(341)
,
Insulin Resistance : CK(1034) : AC(221)
Bitter melon significantly reduces insulin resistance and suppresses visceral fat accumulation.
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2008 Feb;99(2):230-9. Epub 2007 Jul 26. PMID:
17651527
Article Published Date
: Feb 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Bitter Melon : CK(65) : AC(18)
Diseases
:
Insulin Resistance : CK(1034) : AC(221)
,
Metabolic Syndrome X : CK(645) : AC(122)
,
Obesity : CK(1849) : AC(275)
,
Overweight : CK(2176) : AC(342)
Additional Keywords
:
Lipogenesis Inhibitor : CK(2) : AC(1)
Extracts of jambul, bitter melon (M. charantia), gymnena and fenugreek (T. gracecum) have antidiabetic and drug sparing activities.
Click here to read the entire abstract
Pubmed Data
: Appl Biochem Biotechnol. 2009 Nov 11. Epub 2009 Nov 11. PMID:
19904502
Article Published Date
: Nov 11, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Bitter Melon : CK(65) : AC(18)
,
Fenugreek : CK(71) : AC(28)
,
Gymnema Sylvestre : CK(21) : AC(11)
,
Jambul : CK(20) : AC(7)
Diseases
:
Diabetes Mellitus: Type 2 : CK(3429) : AC(341)
Additional Keywords
:
Drug: Glimepiride : CK(2) : AC(1)
,
Drug Sparing : CK(451) : AC(49)
Maitake and Bitter Melon (Momordica charantia) contain alpha-glucosidase inhibitors which may have therapeutic value in diabetes type 2.
Click here to read the entire abstract
Pubmed Data
: Biosci Biotechnol Biochem. 2002 Jul;66(7):1576-8. PMID:
12224646
Article Published Date
: Jul 01, 2002
Study Type
: Animal Study
Additional Links
Substances
:
Bitter Melon : CK(65) : AC(18)
,
Maitake Mushroom : CK(61) : AC(34)
Diseases
:
Diabetes Mellitus: Type 2 : CK(3429) : AC(341)
Pharmacological Actions
:
Alpha-glucosidase inhibitor : CK(20) : AC(13)
,
Enzyme Inhibitors : CK(372) : AC(208)
Bitter melon (M. charantia) compares favorably with insulin and rosiglitazone in potentiating glucose uptake.
Click here to read the entire abstract
Pubmed Data
: Ann N Y Acad Sci. 2006 Nov;1084:391-401. PMID:
19744549
Article Published Date
: Nov 01, 2006
Study Type
: In Vitro Study
Additional Links
Substances
:
Bitter Melon : CK(65) : AC(18)
Diseases
:
Diabetes Mellitus: Type 2 : CK(3429) : AC(341)
Additional Keywords
:
Drug: Rosiglitazone : CK(17) : AC(5)
,
Plant Extracts : CK(3572) : AC(1216)
,
Superiority of Natural Substances versus Drugs : CK(826) : AC(164)
Bitter melon extract, NAC, grape seed extract and other natural antioxidants counteract drug-induced oxidative stress and resultant cell death.
Click here to read the entire abstract
Pubmed Data
: Biofactors. 2004;21(1-4):223-32. PMID:
15630201
Article Published Date
: Jan 01, 2004
Study Type
: Commentary
Additional Links
Substances
:
Antioxidant formulas : CK(487) : AC(73)
,
Bitter Melon : CK(65) : AC(18)
,
Grape Seed Extract : CK(168) : AC(57)
,
NAC (N-acetyl-L-cysteine) : CK(264) : AC(62)
Diseases
:
Oxidative Stress : CK(1945) : AC(710)
Pharmacological Actions
:
Antioxidants : CK(3653) : AC(1318)
Eleostearic acid, a fatty acid found within bitter melon seed oil, inhibits cancer cell proliferation and induce programmed cell death.
Click here to read the entire abstract
Pubmed Data
: Cancer Prev Res (Phila Pa). 2009 Oct;2(10):879-86. Epub 2009 Sep 29. PMID:
19789297
Article Published Date
: Oct 01, 2009
Study Type
: In Vitro Study
Additional Links
Substances
:
Bitter Melon : CK(65) : AC(18)
Diseases
:
Breast Cancer : CK(2354) : AC(621)
Pharmacological Actions
:
Antiproliferative : CK(1052) : AC(775)
,
Apoptotic : CK(1489) : AC(1114)
,
Cell cycle arrest : CK(390) : AC(319)
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