Blueberry

Blueberry

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View the Evidence: Substances

A multi-nutrient mixture of vitamin C, vitamin E, carotenoids, selenium, zinc, amino acids and glycosaminoglycans, blueberry extract and pycnogenol improves visible signs of ageing in women 45-73 years of age.

Pubmed Data : J Dermatolog Treat. 2004 Jul;15(4):222-6. PMID: 15764035
Article Published Date : Jul 01, 2004
Study Type : Human Study
Additional Links
Substances : Amino Acids : CK(100) : AC(16), Blueberry : CK(140) : AC(39), Glycosaminoglycans : CK(12) : AC(2), Pycnogenol (Pine Bark) : CK(385) : AC(61), Selenium : CK(574) : AC(94), Vitamin C : CK(1274) : AC(238), Vitamin E : CK(1285) : AC(221), Zinc : CK(870) : AC(127)
Diseases : Aging Skin : CK(360) : AC(86), Skin Diseases : CK(46) : AC(9)

A topical product containing C-xyloside and blueberry extract improves the appearance of type II diabetic skin.

Pubmed Data : J Cosmet Dermatol. 2009 Jun;8(2):147-51. PMID: 19527341
Article Published Date : Jun 01, 2009
Study Type : Human Study
Additional Links
Substances : Blueberry : CK(140) : AC(39), X-xyloside : CK(10) : AC(1)
Diseases : Advanced Glycation End products (AGE) : CK(2114) : AC(40), Aging Skin : CK(360) : AC(86), Diabetes: Skin : CK(10) : AC(1), Diabetes Mellitus: Type 2 : CK(3429) : AC(341)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Antioxidants (propolis, blueberry, vitamin E) may have value in Peyronie's disease.

Pubmed Data : Int J Androl. 2011 Sep 27. Epub 2011 Sep 27. PMID: 21950543
Article Published Date : Sep 27, 2011
Study Type : Human Study
Additional Links
Substances : Bee Propolis : CK(220) : AC(83), Blueberry : CK(140) : AC(39), Vitamin E : CK(1285) : AC(221)
Diseases : Peyronie's Disease : CK(10) : AC(2)

Bioactives in blueberries improve insulin sensitivity in obese, insulin-resistant men and women.

Pubmed Data : J Nutr. 2010 Aug 19. Epub 2010 Aug 19. PMID: 20724487
Article Published Date : Aug 19, 2010
Study Type : Human Study
Additional Links
Substances : Blueberry : CK(140) : AC(39)
Diseases : Insulin Resistance : CK(1034) : AC(221)

Blueberries decrease cardiovascular risk factors in obese men and women with metabolic syndrome.

Pubmed Data : J Nutr. 2010 Sep;140(9):1582-7. Epub 2010 Jul 21. PMID: 20660279
Article Published Date : Sep 01, 2010
Study Type : Human Study
Additional Links
Substances : Blueberry : CK(140) : AC(39)
Diseases : Cardiovascular Diseases : CK(5138) : AC(641), Metabolic Syndrome X : CK(645) : AC(122), Obesity : CK(1849) : AC(275)
Pharmacological Actions : Hypotensive : CK(383) : AC(53)

Blueberry ingestion improves natural killer cell counts, oxidative stress, and inflammation prior to and after 2.5 h of running.

Pubmed Data : Appl Physiol Nutr Metab. 2011 Dec ;36(6):976-84. Epub 2011 Nov 23. PMID: 22111516
Article Published Date : Dec 01, 2011
Study Type : Human Study
Additional Links
Substances : Blueberry : CK(140) : AC(39)
Diseases : Low Immune Function: Exercise-Induced : CK(40) : AC(4), Low Immune Function: Natural Killer Cells : CK(108) : AC(21)
Pharmacological Actions : Anti-Inflammatory Agents : CK(1230) : AC(433), Antioxidants : CK(3653) : AC(1318)

Blueberry leaf extract reduces fasting glucose, C-reactive protein and plasma aminotransferases in patients with diabetes type 2.

Pubmed Data : Georgian Med News. 2006 Dec;(141):66-72. PMID: 17261891
Article Published Date : Dec 01, 2006
Study Type : Human Study
Additional Links
Substances : Blueberry : CK(140) : AC(39)
Diseases : ALT: Elevated : CK(60) : AC(10), C-Reactive Protein : CK(819) : AC(74), Diabetes Mellitus: Type 2 : CK(3429) : AC(341), GGT : CK(73) : AC(10), Results for Liver Enzymes: Elevated AST : CK(34) : AC(4)
Pharmacological Actions : Anti-Inflammatory Agents : CK(1230) : AC(433)

Just three servings weekly of blueberries or strawberries reduced the risk of heart attack in middle aged women by 33% compared to those eating berries once monthly or less in what seems to be an intake dependant manner.

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Circulation. 2013 Jan 15 ;127(2):188-96. PMID: 23319811
Article Published Date : Jan 14, 2013
Study Type : Human Study
Additional Links
Substances : Anthocyanins : CK(56) : AC(19), Blueberry : CK(140) : AC(39), Strawberry : CK(51) : AC(13)
Diseases : Heart Disease, Myocardial Infarction: Prevention : CK(54) : AC(3)
Pharmacological Actions : Cardioprotective : CK(702) : AC(196)
Additional Keywords : Diet

"Suppression of Wnt1-induced mammary tumor growth and lower serum insulin in offspring exposed to maternal blueberry diet suggest early dietary influence on developmental programming."

Pubmed Data : Carcinogenesis. 2012 Nov 22. Epub 2012 Nov 22. PMID: 23144318
Article Published Date : Nov 21, 2012
Study Type : Animal Study
Additional Links
Substances : Blueberry : CK(140) : AC(39)
Diseases : Prenatal Nutrition: Health of the Offspring : CK(224) : AC(31), Prenatal Nutrition: Prevention of Problems : CK(357) : AC(41)
Additional Keywords : Epigenetic Modification In Cancer : CK(1) : AC(1)

A combination of blueberry, green tea and carnosine have a neuritogenic, and stem-cell regenerative effects in an animal model of neurodegenerative disease.

Pubmed Data : Rejuvenation Res. 2010 Jun 29. Epub 2010 Jun 29. PMID: 20586644
Article Published Date : Jun 29, 2010
Study Type : Animal Study
Additional Links
Substances : Blueberry : CK(140) : AC(39)
Diseases : Neurodegenerative Diseases : CK(1743) : AC(420)
Pharmacological Actions : Neuritogenic : CK(98) : AC(48)
Additional Keywords : Stem Cell Generation : CK(16) : AC(5)

Anthocyanins in aged blueberry-fed rats are found centrally and may enhance memory.

Pubmed Data : BMB Rep. 2010 Jan;43(1):46-51. PMID: 16053243
Article Published Date : Jan 01, 2010
Study Type : Animal Study
Additional Links
Substances : Anthocyanins : CK(56) : AC(19), Blueberry : CK(140) : AC(39)
Diseases : Aging: Brain : CK(1747) : AC(68), Memory Disorders : CK(221) : AC(67)
Pharmacological Actions : Neuroprotective Agents : CK(962) : AC(480)

Berries and ellagic acid prevent estrogen-induced mammary tumorigenesis by modulating enzymes of estrogen metabolism.

Pubmed Data : Cancer Prev Res (Phila Pa). 2010 Jun;3(6):727-37. Epub 2010 May 25. PMID: 20501861
Article Published Date : Jun 01, 2010
Study Type : Animal Study
Additional Links
Substances : Berries: All : CK(780) : AC(199), Blueberry : CK(140) : AC(39), Ellagic Acid : CK(77) : AC(40), Raspberry : CK(21) : AC(11)
Diseases : Breast Cancer : CK(2354) : AC(621), Estrogen Dominance : CK(106) : AC(37), Estrogen Dysregulation: 2/4/16 hydroxyestrone ratios : CK(40) : AC(9)
Pharmacological Actions : Chemopreventive : CK(1528) : AC(382), Estradiol Antagonists : CK(2) : AC(1)

Biotransformed (fermented) blueberry juice exhibits antiobesity and antidiabetic in mice.

Pubmed Data : Int J Obes (Lond). 2009 Oct;33(10):1166-73. Epub 2009 Aug 18. PMID: 19687792
Article Published Date : Oct 01, 2009
Study Type : Animal Study
Additional Links
Substances : Blueberry : CK(140) : AC(39), Fermented Foods and Beverages : CK(670) : AC(133)
Diseases : Diabetes Mellitus: Type 1 : CK(1107) : AC(218), Obesity : CK(1849) : AC(275)

Blueberries have a beneficial effect in an experimental animal model of multiple sclerosis.

Pubmed Data : J Agric Food Chem. 2012 Feb 10. Epub 2012 Feb 10. PMID: 22243431
Article Published Date : Feb 10, 2012
Study Type : Animal Study
Additional Links
Substances : Blueberry : CK(140) : AC(39)
Diseases : Multiple Sclerosis : CK(716) : AC(133)

Blueberry attenuates microglial activation in the brain suggesting it may attenuate age-induced inflammation.

Pubmed Data : Glia. 2009 Dec 14. PMID: 20014277
Article Published Date : Dec 14, 2009
Study Type : Animal Study
Additional Links
Substances : Blueberry : CK(140) : AC(39)
Diseases : Aging: Brain : CK(1747) : AC(68), Brain: Microglial Activation : CK(67) : AC(38), Brain Inflammation : CK(79) : AC(35)
Pharmacological Actions : Anti-Inflammatory Agents : CK(1230) : AC(433), Interleukin-6 Downregulation : CK(470) : AC(135), Neuroprotective Agents : CK(962) : AC(480)

Blueberry consumption inhibits angiogenic tumor growth and enhances the survival of mice with hemangioendothelioma.

Pubmed Data : Antioxid Redox Signal. 2009 Jan;11(1):47-58. PMID: 18817478
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Substances : Blueberry : CK(140) : AC(39)
Diseases : Hemangioendothelioma : CK(5) : AC(2), Hemangioma : CK(6) : AC(4), Vascular Neoplasm : CK(4) : AC(3)
Pharmacological Actions : Anti-Angiogenic : CK(143) : AC(101)

Blueberry consumption may have a positive effect on blood pressure through the modulation of arterial contraction.

Pubmed Data : J Nutr Biochem. 2010 Jan;21(1):14-22. Epub 2009 Jan 20. PMID: 19157824
Article Published Date : Jan 01, 2010
Study Type : Animal Study
Additional Links
Substances : Blueberry : CK(140) : AC(39)
Diseases : Hypertension : CK(2783) : AC(271)

Blueberry contains water soluble compounds that have protective effects against oxidative damage.

Pubmed Data : Nutr Res Pract. 2010 Jun;4(3):183-90. Epub 2010 Jun 29. PMID: 20607062
Article Published Date : Jun 01, 2010
Study Type : Animal Study
Additional Links
Substances : Blueberry : CK(140) : AC(39)
Diseases : Oxidative Stress : CK(1945) : AC(710)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

Blueberry diets in early life prevent senescence of osteoblasts and bone loss in ovariectomized adult female rats.

Pubmed Data : PLoS One. 2011 ;6(9):e24486. Epub 2011 Sep 2. PMID: 21912699
Article Published Date : Jan 01, 2011
Study Type : Animal Study
Additional Links
Substances : Blueberry : CK(140) : AC(39)
Diseases : Aging : CK(1351) : AC(369), Osteoporosis : CK(1171) : AC(205)
Additional Keywords : Ovariectomy-Induced Changes : CK(52) : AC(22)

Blueberry exhibits cardioprotective properties in an animal model.

Pubmed Data : J Agric Food Chem. 2011 Sep 28 ;59(18):10381-7. Epub 2011 Sep 1. PMID: 21866950
Article Published Date : Sep 28, 2011
Study Type : Animal Study
Additional Links
Substances : Blueberry : CK(140) : AC(39)
Diseases : Atherosclerosis : CK(523) : AC(77), Inflammation : CK(1077) : AC(363)
Pharmacological Actions : Cardioprotective : CK(702) : AC(196)

Blueberry extract prolongs lifespan of the fruit fly.

Pubmed Data : Exp Gerontol. 2012 Feb ;47(2):170-8. Epub 2011 Dec 17. PMID: 22197903
Article Published Date : Feb 01, 2012
Study Type : Animal Study
Additional Links
Substances : Blueberry : CK(140) : AC(39)
Diseases : Aging : CK(1351) : AC(369)

Blueberry has a protective effect in an experimental model of inflammatory bowel disease.

Pubmed Data : Evid Based Complement Alternat Med. 2011 ;2011:525462. Epub 2011 Apr 14. PMID: 21785630
Article Published Date : Jan 01, 2011
Study Type : Animal Study
Additional Links
Substances : Blueberry : CK(140) : AC(39)
Diseases : Inflammatory Bowel Diseases : CK(1227) : AC(103)
Pharmacological Actions : Anti-Inflammatory Agents : CK(1230) : AC(433), Interleukin-12 downregulation : CK(9) : AC(5), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)

Blueberry inhibits the growth and metastatic potential of triple negative breast cancer in vitro and in vivo.

Pubmed Data : Cancer Res. 2010 May 1;70(9):3594-605. Epub 2010 Apr 13. PMID: 20388778
Article Published Date : May 01, 2010
Study Type : Animal Study
Additional Links
Substances : Blueberry : CK(140) : AC(39), Flavonoids : CK(909) : AC(289), Polyphenols : CK(427) : AC(174)
Diseases : Breast Cancer : CK(2354) : AC(621), Breast Cancer: Metastatic : CK(82) : AC(33), Breast Cancer: Triple Negative : CK(61) : AC(13)
Pharmacological Actions : Apoptotic : CK(1489) : AC(1114), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(153) : AC(71)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Blueberry juice has potent vasorelaxing properties, and thus may be a useful dietary agent for the prevention and treatment of hypertension.

Pubmed Data : Food Funct. 2012 Nov 22. Epub 2012 Nov 22. PMID: 23175156
Article Published Date : Nov 21, 2012
Study Type : Animal Study
Additional Links
Substances : Blueberry : CK(140) : AC(39)
Diseases : Hypertension : CK(2783) : AC(271)
Pharmacological Actions : Vasodilator Agents : CK(262) : AC(54)

Blueberry polyphenolic compounds prevent oleic acid-induced fatty liver in vitro.

Pubmed Data : J Agric Food Chem. 2011 Nov 23 ;59(22):12254-63. Epub 2011 Nov 1. PMID: 21999238
Article Published Date : Nov 23, 2011
Study Type : Animal Study
Additional Links
Substances : Blueberry : CK(140) : AC(39)
Diseases : Fatty Liver : CK(493) : AC(122)
Pharmacological Actions : Hepatoprotective : CK(557) : AC(272)

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