Broccoli

Broccoli

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View the Evidence: Substances

Evidence exists indicating that Brassica vegetables reduce prostate cancer risk.

Pubmed Data : Nutr Cancer. 2002;42(1):1-9. PMID: 12235639
Article Published Date : Jan 01, 2002
Study Type : Meta Analysis
Additional Links
Substances : Bok Choy : CK(20) : AC(1), Broccoli : CK(449) : AC(185), Cabbage : CK(65) : AC(13), Collards : CK(53) : AC(6), Kale : CK(43) : AC(6), Mustard Greens : CK(39) : AC(12)
Diseases : Prostate Cancer: Prevention : CK(155) : AC(16)
Pharmacological Actions : Anticarcinogenic Agents : CK(521) : AC(275)
Additional Keywords : Risk Reduction : CK(1909) : AC(196)

A combination of ascorbigen (a food derived form of vitamin c) and broccoli powder reduces pain sensivitiy and improves quality of life in patients with fibromyalgia.

Pubmed Data : Altern Med Rev. 2000 Oct;5(5):455-62. PMID: 11056415
Article Published Date : Oct 01, 2000
Study Type : Human Study
Additional Links
Substances : Broccoli : CK(449) : AC(185), Vitamin C : CK(1274) : AC(238)
Diseases : Fibromyalgia : CK(537) : AC(57)

A human clinical study demonstrates that diets rich in cruciferous vegetables may reduce the risk of prostate cancer.

Pubmed Data : PLoS One. 2008;3(7):e2568. Epub 2008 Jul 2. PMID: 18596959
Article Published Date : Jan 01, 2008
Study Type : Human Study
Additional Links
Substances : Broccoli : CK(449) : AC(185)
Diseases : Prostate Cancer : CK(998) : AC(288)

Broccoli sprouts reduce colonization and attenuate gastritis in Helicobacter pylori-infected mice and humans.

Pubmed Data : Cancer Prev Res (Phila Pa). 2009 Apr;2(4):353-60. PMID: 19349290
Article Published Date : Apr 01, 2009
Study Type : Human Study
Additional Links
Substances : Broccoli : CK(449) : AC(185), Sprouts : CK(76) : AC(36), Sulforaphane : CK(520) : AC(171)
Diseases : Gastritis : CK(291) : AC(8), Helicobacter Pylori Infection : CK(305) : AC(61)

Oral broccoli sprouts have significant therapeutic value in the treatment of Helicobacter pylori infection.

Pubmed Data : Dig Dis Sci. 2004 Aug;49(7-8):1088-90. PMID: 15387326
Article Published Date : Aug 01, 2004
Study Type : Human Study
Additional Links
Substances : Broccoli : CK(449) : AC(185), Sprouts : CK(76) : AC(36)
Diseases : Helicobacter Pylori Infection : CK(305) : AC(61)
Pharmacological Actions : Anti-Bacterial Agents : CK(970) : AC(316)

Oral sulforaphane safely and effectively induces mucosal Phase II enzyme expression in the upper airway of human subjects.

Pubmed Data : Clin Immunol. 2009 Mar;130(3):244-51. Epub 2008 Nov 22. PMID: 19028145
Article Published Date : Mar 01, 2009
Study Type : Human Study
Additional Links
Substances : Sulforaphane : CK(520) : AC(171)
Diseases : COPD : CK(158) : AC(18), Cystic Fibrosis : CK(703) : AC(77), Glutathione Deficiency : CK(63) : AC(14), Lung Diseases : CK(32) : AC(5), Pulmonary Fibrosis : CK(135) : AC(46), Respiratory Diseases : CK(174) : AC(29)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Glutathione Upregulation : CK(144) : AC(48), Phase II Detoxification Enzyme Inducer : CK(64) : AC(32)
Additional Keywords : Isothiocyanates : CK(70) : AC(23)

Raw broccoli results in faster absorption, higher bioavailability, and higher peak plasma amounts of sulforaphane, compared to cooked broccoli.

Pubmed Data : J Agric Food Chem. 2008 Nov 26;56(22):10505-9. PMID: 18950181
Article Published Date : Nov 26, 2008
Study Type : Human Study
Additional Links
Substances : Broccoli : CK(449) : AC(185), Sulforaphane : CK(520) : AC(171)
Pharmacological Actions : Anticarcinogenic Agents : CK(521) : AC(275)
Additional Keywords : Raw versus Cooked : CK(69) : AC(13)

Safety Study: Brocolli sprouts (sulforaphane) are safe, tolerable and do not adversely effect thyroid hormone levels.

Pubmed Data : Nutr Cancer. 2006;55(1):53-62. PMID: 16965241
Article Published Date : Jan 01, 2006
Study Type : Human Study
Additional Links
Substances : Broccoli : CK(449) : AC(185), Sprouts : CK(76) : AC(36), Sulforaphane : CK(520) : AC(171)
Pharmacological Actions : Anticarcinogenic Agents : CK(521) : AC(275)
Additional Keywords : Isothiocyanates : CK(70) : AC(23), Plant Extracts : CK(3572) : AC(1216)

Sulforaphane has a novel chemopreventive mechanism in human colon cancer cells and prostate epithelial cells, namely the inhibition of histone deacetylase (HDAC). I

Pubmed Data : Exp Biol Med (Maywood). 2007 Feb;232(2):227-34. PMID: 17259330
Article Published Date : Feb 01, 2007
Study Type : Human Study
Additional Links
Substances : Sulforaphane : CK(520) : AC(171)
Diseases : Colon Cancer : CK(895) : AC(233), Prostate Cancer : CK(998) : AC(288), Prostate Cancer: Prevention : CK(155) : AC(16)
Pharmacological Actions : Chemopreventive : CK(1528) : AC(382), Enzyme Inhibitors : CK(372) : AC(208), Histone deacetylase inhibitor : CK(26) : AC(16)

Sulforaphane protects against chemically-induced damage in bladder cells and tissues.

Pubmed Data : Phytother Res. 2003 Jan;17(1):66-9. PMID: 20810543
Article Published Date : Jan 01, 2003
Study Type : Human Study
Additional Links
Substances : Sulforaphane : CK(520) : AC(171)
Diseases : Bladder Cancer : CK(186) : AC(60), Bladder Degeneration : CK(22) : AC(3), DNA damage : CK(711) : AC(293)
Pharmacological Actions : Chemopreventive : CK(1528) : AC(382), Genoprotective : CK(116) : AC(48)

Sulforaphane-containing broccoli sprout extracts induce a cytoprotective phase 2 response in mouse and human skin.

Pubmed Data : Cancer Epidemiol Biomarkers Prev. 2007 Apr;16(4):847-51. PMID: 17416783
Article Published Date : Apr 01, 2007
Study Type : Human Study
Additional Links
Substances : Broccoli : CK(449) : AC(185), Sulforaphane : CK(520) : AC(171)
Diseases : Skin Diseases : CK(46) : AC(9)
Pharmacological Actions : Phase II Detoxification Enzyme Inducer : CK(64) : AC(32)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

The bioavailability of isothiocyanates from fresh broccoli is approximately three times greater than that from cooked broccoli,

Pubmed Data : Nutr Cancer. 2000;38(2):168-78. PMID: 11525594
Article Published Date : Jan 01, 2000
Study Type : Human Study
Additional Links
Substances : Broccoli : CK(449) : AC(185), Sulforaphane : CK(520) : AC(171)
Pharmacological Actions : Anticarcinogenic Agents : CK(521) : AC(275)
Additional Keywords : Raw versus Cooked : CK(69) : AC(13)

Electron microscopy revealed that both plantain and broccoli markedly reduced E. coli translocation across cells, while the emulsifier Polysorbate-80 increased E. coli translocation.

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Gut. 2010 Oct ;59(10):1331-9. Epub 2010 Sep 2. PMID: 20813719
Article Published Date : Oct 01, 2010
Study Type : Human In Vitro
Additional Links
Substances : Broccoli : CK(449) : AC(185), Fiber : CK(484) : AC(70), Plantain : CK(39) : AC(12)
Diseases : Enterococcus Infections : CK(3) : AC(3)

The addition of broccoli and watercress in the diet may reduce risk of breast cancer

Pubmed Data : Toxicol Appl Pharmacol. 2005 Dec 1 ;209(2):105-13. Epub 2005 Jun 13. PMID: 15953625
Article Published Date : Dec 01, 2005
Study Type : Human In Vitro
Additional Links
Substances : Broccoli : CK(449) : AC(185), Sulforaphane : CK(520) : AC(171), Watercress : CK(14) : AC(4)
Diseases : Breast Cancer : CK(2354) : AC(621)
Pharmacological Actions : Anticarcinogenic Agents : CK(521) : AC(275), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(153) : AC(71)
Additional Keywords : Isothiocyanates : CK(70) : AC(23), Plant Extracts : CK(3572) : AC(1216)

"Inhibition of bladder cancer by broccoli isothiocyanates sulforaphane and erucin."

Pubmed Data : Mol Nutr Food Res. 2012 Nov ;56(11):1675-87. Epub 2012 Oct 5. PMID: 23038615
Article Published Date : Oct 31, 2012
Study Type : Animal Study
Additional Links
Substances : Erucin : CK(2) : AC(1), Sulforaphane : CK(520) : AC(171)
Diseases : Bladder Cancer : CK(186) : AC(60)
Pharmacological Actions : Chemopreventive : CK(1528) : AC(382)

"Inhibition of Epstein-Barr virus reactivation in nasopharyngeal carcinoma cells by dietary sulforaphane."

Pubmed Data : Mol Carcinog. 2012 May 29. Epub 2012 May 29. PMID: 22641235
Article Published Date : May 28, 2012
Study Type : Insect Study
Additional Links
Substances : Sulforaphane : CK(520) : AC(171)
Diseases : Epstein-Barr Virus Infections : CK(100) : AC(43), Nasopharyngeal Cancer : CK(58) : AC(21)

"Neuroprotective effects of sulforaphane after contusive spinal cord injury."

Pubmed Data : J Neurotrauma. 2012 Nov 1 ;29(16):2576-86. Epub 2012 Sep 20. PMID: 22853439
Article Published Date : Oct 31, 2012
Study Type : Animal Study
Additional Links
Substances : Sulforaphane : CK(520) : AC(171)
Diseases : Spinal Cord Injuries : CK(98) : AC(28)
Pharmacological Actions : Neuroprotective Agents : CK(962) : AC(480)

"Prevention of diabetic nephropathy by sulforaphane: possible role of Nrf2 upregulation and activation."

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2012 ;2012:821936. Epub 2012 Sep 23. PMID: 23050040
Article Published Date : Dec 31, 2011
Study Type : Animal Study
Additional Links
Substances : Sulforaphane : CK(520) : AC(171)
Diseases : Diabetic Nephropathy : CK(43) : AC(17)

"Protective effects of the antioxidant sulforaphane on behavioral changes and neurotoxicity in mice after the administration of methamphetamine."

Pubmed Data : Psychopharmacology (Berl). 2012 Jul ;222(1):37-45. Epub 2011 Dec 27. PMID: 22200890
Article Published Date : Jun 30, 2012
Study Type : Animal Study
Additional Links
Substances : Sulforaphane : CK(520) : AC(171)
Diseases : Amphetamine Addiction/Withdrawal : CK(31) : AC(8), Brain: Microglial Activation : CK(67) : AC(38), Neurodegenerative Diseases : CK(1743) : AC(420)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Neuroprotective Agents : CK(962) : AC(480)

Related Blogs

Broccoli Sprouts and Their Effect on Breast Cancer
Written by Dr. Veronique Desaulniers
Cruciferous vegetables such as broccoli, Brussels sprouts and cabbages contain many valuable phytochemicals, vitamins and minerals. In fact, in the late 90’s, published studies indicated that there was a link between protection against Breast Cancer and the consumption of cruciferous vegetables

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