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Article Count - 92
Cumulative Knowledge - 392

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Quick Summary: Current access displays 2 out of 92 associated Diseases

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View the Evidence: Substances

Cannabis contains a number of compounds which may have therapeutic value in delaying the progression of ALS.

Click here to read the entire abstract

Pubmed Data : Amyotroph Lateral Scler Other Motor Neuron Disord. 2004 Mar;5(1):33-9. PMID: 15204022

Article Published Date : Mar 01, 2004

Study Type : Animal Study

Additional Links

Substances : Cannabinoids : CK(195) : AC(53), Cannabis : CK(738) : AC(132)

Diseases : Amyotrophic Lateral Sclerosis : CK(350) : AC(68)

Pharmacological Actions : Neuroprotective Agents : CK(962) : AC(480)

Cannabis sativa extract attenuates diabetic neuropathic pain in rats.

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2009 May 13;23(12):1678-1684. PMID: 19441010

Article Published Date : May 13, 2009

Study Type : Animal Study

Additional Links

Substances : Marihuana : CK(727) : AC(139)

Diseases : Diabetic Neuropathies : CK(203) : AC(32)

THC and cannabidiol may have therapeutic value in reducing damage and inflammation associated with colitis.

Click here to read the entire abstract

Pubmed Data : Br J Pharmacol. 2010 Jun;160(3):712-23. PMID: 20590574

Article Published Date : Jun 01, 2010

Study Type : Animal Study

Additional Links

Substances : Cannabidiol : CK(391) : AC(92), Cannabis : CK(738) : AC(132), Delta-tetrahydrocannabinol (THC) : CK(391) : AC(90)

Diseases : Colitis : CK(368) : AC(53), Inflammatory Bowel Diseases : CK(1227) : AC(103)

Pharmacological Actions : Anti-Inflammatory Agents : CK(1230) : AC(433)

The CB2 cannabinoid agonist AM-1241 prolongs survival (56%) in a transgenic mouse model of amyotrophic lateral sclerosis when initiated at symptom onset.

Click here to read the entire abstract

Pubmed Data : Curr Eye Res. 2005 Jul;30(7):583-91. PMID: 17241118

Article Published Date : Jul 01, 2005

Study Type : Animal Study

Additional Links

Substances : Cannabinoids : CK(195) : AC(53)

Diseases : Amyotrophic Lateral Sclerosis : CK(350) : AC(68)

Pharmacological Actions : Neuroprotective Agents : CK(962) : AC(480)

Treatment with cannabidiol reverses oxidative stress parameters, cognitive impairment and mortality in rats submitted to sepsis by cecal ligation and puncture.

Click here to read the entire abstract

Pubmed Data : Brain Res. 2010 Aug 12;1348:128-38. Epub 2010 Jun 16. PMID: 20561509

Article Published Date : Aug 12, 2010

Study Type : Animal Study

Additional Links

Substances : Cannabidiol : CK(391) : AC(92), Cannabis : CK(738) : AC(132)

Diseases : Endotoxemia : CK(187) : AC(40), Sepsis : CK(187) : AC(26)

Treatment with cannabidiol significantly reduces primary mammary tumor mass as well as the size and number of lung metastic foci in animals.

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Pubmed Data : Breast Cancer Res Treat. 2010 Sep 22. Epub 2010 Sep 22. PMID: 20859676

Article Published Date : Sep 22, 2010

Study Type : Animal Study

Additional Links

Substances : Cannabidiol : CK(391) : AC(92), Cannabis : CK(738) : AC(132)

Diseases : Breast Cancer : CK(2354) : AC(621), Breast Cancer: Lung Metastasis : CK(13) : AC(7), Breast Cancer: Prevention : CK(525) : AC(73), Cancer Metastasis : CK(272) : AC(135)

Pharmacological Actions : Anti-metastatic : CK(192) : AC(115), Antiproliferative : CK(1052) : AC(775)

"Endocannabinoids in nervous system health and disease: the big picture in a nutshell."

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Philos Trans R Soc Lond B Biol Sci. 2012 Dec 5 ;367(1607):3193-200. PMID: 23108539

Article Published Date : Dec 04, 2012

Study Type : Review

Additional Links

Substances : Cannabinoids : CK(195) : AC(53)

Diseases : Endocannabinoid System : CK(16) : AC(6)

A cannabinoid quinone has anti-angiogenic and anticancer activity.

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Pubmed Data : Mol Pharmacol. 2006 Jul;70(1):51-9. Epub 2006 Mar 29. PMID: 16571653

Article Published Date : Jul 01, 2006

Study Type : In Vitro Study

Additional Links

Substances : Marihuana : CK(727) : AC(139)

Diseases : Cancer Metastasis : CK(272) : AC(135), Cancers: All : CK(9062) : AC(2869)

Pharmacological Actions : Anti-Angiogenic : CK(143) : AC(101), Anti-Tumor : CK(69) : AC(44)

A cannabinoid quinone has cancer-destroying activity superior to doxorubicin without cardiotoxicity, in vitro.

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Pubmed Data : Expert Opin Investig Drugs. 2007 Sep;16(9):1405-13. PMID: 17714026

Article Published Date : Sep 01, 2007

Study Type : In Vitro Study

Additional Links

Substances : Marihuana : CK(727) : AC(139)

Diseases : Cancers: All : CK(9062) : AC(2869), Chemotherapy-Induced Toxicity: Doxorubicin : CK(59) : AC(25)

Additional Keywords : Superiority of Natural Substances versus Drugs : CK(826) : AC(164)

Ajulemic acid, a compound found within marihuana, may have therapeutic value in the treatment of rheumatoid arthritis and osteoporosis.

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Pubmed Data : J Cell Physiol. 2008 Mar;214(3):714-20. PMID: 17786950

Article Published Date : Mar 01, 2008

Study Type : In Vitro Study

Additional Links

Substances : Marihuana : CK(727) : AC(139)

Diseases : Arthritis: Rheumatoid : CK(289) : AC(54), Osteoporosis : CK(1171) : AC(205)

Cannabidiol and (-)Delta9-tetrahydrocannabinol are neuroprotective antioxidants.

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Proc Natl Acad Sci U S A. 1998 Jul 7 ;95(14):8268-73. PMID: 9653176

Article Published Date : Jul 06, 1998

Study Type : Review

Additional Links

Substances : Cannabidiol : CK(391) : AC(92), Delta-tetrahydrocannabinol (THC) : CK(391) : AC(90)

Diseases : Brain Inflammation : CK(79) : AC(35), Cerebral Ischemia : CK(263) : AC(50), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Neuroprotective Agents : CK(962) : AC(480)

Cannabidiol exhibits anti-invasive action on human lung cancer cells.

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Pubmed Data : Pharm Res. 2010 Oct;27(10):2162-74. Epub 2010 Jul 29. PMID: 20668920

Article Published Date : Oct 01, 2010

Study Type : In Vitro Study

Additional Links

Substances : Cannabidiol : CK(391) : AC(92), Cannabis : CK(738) : AC(132)

Diseases : Cancer Metastasis : CK(272) : AC(135), Lung Cancer : CK(496) : AC(198)

Pharmacological Actions : Anti-metastatic : CK(192) : AC(115)

Cannabidiol has a potential therapeutic agent for the treatment of liver fibrosis.

Click here to read the entire abstract

Pubmed Data : Cell Death Dis. 2011 ;2:e170. Epub 2011 Jun 9. PMID: 21654828

Article Published Date : Jan 01, 2011

Study Type : In Vitro Study

Additional Links

Substances : Cannabidiol : CK(391) : AC(92)

Diseases : Liver Fibrosis : CK(341) : AC(74)

Pharmacological Actions : Apoptotic : CK(1489) : AC(1114)

Cannabidiol induces programmed cell death in breast cancer cells.

Click here to read the entire abstract

Pubmed Data : Antiviral Res. 2005 Nov;68(2):66-74. Epub 2005 Aug 9. PMID: 21566064

Article Published Date : Nov 01, 2005

Study Type : In Vitro Study

Additional Links

Substances : Cannabidiol : CK(391) : AC(92)

Diseases : Breast Cancer : CK(2354) : AC(621)

Pharmacological Actions : Apoptotic : CK(1489) : AC(1114), Autophagy Up-regulation : CK(18) : AC(13)

Cannabidiol inhibits cancer cell invasion via upregulation of tissue inhibitor of matrix metalloproteinases-1.

Click here to read the entire abstract

Pubmed Data : Biochem Pharmacol. 2010 Apr 1;79(7):955-66. Epub 2009 Nov 13. PMID: 19914218

Article Published Date : Apr 01, 2010

Study Type : In Vitro Study

Additional Links

Substances : Cannabidiol : CK(391) : AC(92), Cannabis : CK(738) : AC(132)

Diseases : Cancer Metastasis : CK(272) : AC(135), Lung Cancer : CK(496) : AC(198)

Pharmacological Actions : Antineoplastic Agents : CK(877) : AC(496), Matrix metalloproteinase-1 (MMP-1) inhibitor : CK(17) : AC(7)

Cannabidiol is a novel inhibitor of a gene associated with aggressive breast cancer.

Click here to read the entire abstract

Pubmed Data : Mol Cancer Ther. 2007 Nov;6(11):2921-7. PMID: 18025276

Article Published Date : Nov 01, 2007

Study Type : In Vitro Study

Additional Links

Substances : Cannabidiol : CK(391) : AC(92)

Diseases : Breast Cancer : CK(2354) : AC(621), Cancer Metastasis : CK(272) : AC(135)

Pharmacological Actions : Antineoplastic Agents : CK(877) : AC(496), Antiproliferative : CK(1052) : AC(775)

Cannabidiol is cytotoxic to human glioma cells.

Click here to read the entire abstract

Pubmed Data : Cell Mol Life Sci. 2006 Sep;63(17):2057-66. PMID: 16909207

Article Published Date : Sep 01, 2006

Study Type : In Vitro Study

Additional Links

Substances : Cannabidiol : CK(391) : AC(92)

Diseases : Glioma : CK(74) : AC(40)

Pharmacological Actions : Anti-Proliferative : CK(55) : AC(49), Caspase-3 Activation : CK(23) : AC(15)

Cannabidiol may have therapeutic value as an antipsychotic drug.

Click here to read the entire abstract

Pubmed Data : Braz J Med Biol Res. 2006 Apr;39(4):421-9. Epub 2006 Apr 3. PMID: 16612464

Article Published Date : Apr 01, 2006

Study Type : Review

Additional Links

Substances : Cannabidiol : CK(391) : AC(92)

Diseases : Psychoses : CK(12) : AC(3)

Pharmacological Actions : Anti-Psychotic : CK(1) : AC(1)

Cannabidiol, a non-psychoactive component from Cannabis sativa, exhibits neuroprotective, antioxidant and anti-apoptotic effect against beta-amyloid peptide toxicity.

Click here to read the entire abstract

Pubmed Data : Fitoterapia. 2011 Jan 26. Epub 2011 Jan 26. PMID: 15030397

Article Published Date : Jan 26, 2011

Study Type : In Vitro Study

Additional Links

Substances : Marihuana : CK(727) : AC(139)

Diseases : Alzheimer's Disease : CK(826) : AC(160), Neurodegenerative Diseases : CK(1743) : AC(420)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Neuroprotective Agents : CK(962) : AC(480)

Cannabidiol, a non-psychoactive component from Cannabis sativa, is a potent inhibitor of breast and thyroid cancer cells.

Click here to read the entire abstract

Pubmed Data : J Pharmacol Exp Ther. 2006 Sep;318(3):1375-87. Epub 2006 May 25. PMID: 16728591

Article Published Date : Sep 01, 2006

Study Type : In Vitro Study

Additional Links

Substances : Marihuana : CK(727) : AC(139)

Diseases : Breast Cancer : CK(2354) : AC(621), Thyroid Cancer : CK(162) : AC(32)

Pharmacological Actions : Anti-Tumor : CK(69) : AC(44), Apoptotic : CK(1489) : AC(1114)

Cannabinoids has novel anti-inflammatory activity.

Click here to read the entire abstract

Pubmed Data : Future Med Chem. 2009 Oct;1(7):1333-1349. PMID: 20191092

Article Published Date : Oct 01, 2009

Study Type : Review

Additional Links

Substances : Marihuana : CK(727) : AC(139)

Diseases : Inflammation : CK(1077) : AC(363)

Pharmacological Actions : Anti-Inflammatory Agents : CK(1230) : AC(433)

Cannabinoids and endocannabinoids may have therapeutic value in metabolic disorders and diabetes.

Click here to read the entire abstract

Pubmed Data : Handb Exp Pharmacol. 2011(203):75-104. PMID: 21484568

Article Published Date : Jan 01, 2011

Study Type : Review

Additional Links

Substances : Cannabinoids : CK(195) : AC(53), Cannabis : CK(738) : AC(132), Endocannabinoids : CK(1) : AC(1)

Diseases : Diabetes Mellitus: Type 1: Prevention : CK(197) : AC(30), Diabetes Mellitus: Type 2 : CK(3429) : AC(341), Endocannabinoid System : CK(16) : AC(6)

Additional Keywords : Beta Cell Protection : CK(53) : AC(22)

Cannabinoids have a potential therapeutic value in the treatment of psoriasis.

Click here to read the entire abstract

Pubmed Data : J Dermatol Sci. 2007 Feb;45(2):87-92. Epub 2006 Dec 6. PMID: 17157480

Article Published Date : Feb 01, 2007

Study Type : In Vitro Study

Additional Links

Substances : Marihuana : CK(727) : AC(139)

Diseases : Psoriasis : CK(270) : AC(42)

Related Blogs

A Higher Level of Freedom: The Benefit of Cannabis To Health

Written by Sayer Ji, Founder

In a day and age where possession of an herb like cannabis – which grows freely on this Earth -- is an offense sometimes punishable by incarceration, it is important for us to reflect on how we arrived at this dark point in time. Herbs, after all, were put there by God. If you prefer the word Nature, the point is the same, and it was put best by Bob Marley when he said: "you can't tell God it [cannabis] is illegal."

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