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Article Count - 53
Cumulative Knowledge - 195

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Quick Summary: Current access displays 2 out of 63 associated Diseases

Name	Cumulative Knowledge	Article Count	Focus Articles
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View the Evidence: Substances

Cannabinoids may have possible therapeutic properties for the management of the multiple sclerosis.

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 2010 Nov 19. Epub 2010 Nov 19. PMID: 21094240

Article Published Date : Nov 19, 2010

Study Type : Meta Analysis

Additional Links

Substances : Cannabinoids : CK(195) : AC(53)

Diseases : Multiple Sclerosis : CK(716) : AC(133)

A tetrahydrocannabinol:cannabidiol (THC:CBD) extract is efficacious for relief of pain in patients with advanced cancer pain not fully relieved by strong opioids.

Click here to read the entire abstract

Pubmed Data : Hum Reprod. 2009 Jul;24(7):1717-25. Epub 2009 Mar 11. PMID: 19896326

Article Published Date : Jul 01, 2009

Study Type : Human Study

Additional Links

Substances : Cannabidiol : CK(391) : AC(92)

Diseases : Cancers: All : CK(9062) : AC(2869), Pain : CK(616) : AC(91)

Pharmacological Actions : Analgesics : CK(372) : AC(78)

Cannabidiol has antipsychotic properties which balance out the psychotomimetic effects of THC in cannabis.

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Pubmed Data : Br J Psychiatry. 2008 Apr;192(4):306-7. PMID: 18378995

Article Published Date : Apr 01, 2008

Study Type : Human Study

Additional Links

Substances : Cannabidiol : CK(391) : AC(92)

Diseases : Delirium: Drug-Induced : CK(26) : AC(6), Marijuana Addiction/Withdrawal : CK(34) : AC(6)

Additional Keywords : The Whole is Superior to the Monochemical Part : CK(16) : AC(5), Whole Food Balance : CK(10) : AC(1)

Cannabidiol levels in different strains of cannabis may determine the degree to which THC interferes with memory in users.

Click here to read the entire abstract

Pubmed Data : Br J Psychiatry. 2010 Oct;197(4):285-90. PMID: 20884951

Article Published Date : Oct 01, 2010

Study Type : Human Study

Additional Links

Substances : Cannabidiol : CK(391) : AC(92), Cannabis : CK(738) : AC(132)

Diseases : Marijuana Addiction/Withdrawal : CK(34) : AC(6), Memory Disorders : CK(221) : AC(67)

Cannabidiol reduces anxiety in social anxiety disorder through modulating the limbic and paralimbic brain areas.

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Pubmed Data : J Psychopharmacol. 2010 Sep 9. Epub 2010 Sep 9. PMID: 20829306

Article Published Date : Sep 09, 2010

Study Type : Human Study

Additional Links

Substances : Cannabidiol : CK(391) : AC(92), Cannabis : CK(738) : AC(132)

Diseases : Anxiety Disorders : CK(659) : AC(82), Social Anxiety Disorder (SAD) : CK(10) : AC(1)

Pharmacological Actions : Anxiolytic : CK(268) : AC(41)

Cannabinoids may have therapeutic value in the treatment of tics in Tourette syndrome.

Click here to read the entire abstract

Pubmed Data : Expert Opin Pharmacother. 2003 Oct;4(10):1717-25. PMID: 14521482

Article Published Date : Oct 01, 2003

Study Type : Human Study

Additional Links

Substances : Cannabinoids : CK(195) : AC(53), Cannabis : CK(738) : AC(132), Delta-tetrahydrocannabinol (THC) : CK(391) : AC(90)

Diseases : Tourette Syndrome : CK(139) : AC(17)

Cannabis is well-tolerated and efficacious in the treatment of neuropathic pain from brachial plexus avulsion.

Click here to read the entire abstract

Pubmed Data : Pain. 2004 Dec;112(3):299-306. PMID: 15561385

Article Published Date : Dec 01, 2004

Study Type : Human Study

Additional Links

Substances : Cannabidiol : CK(391) : AC(92), Cannabis : CK(738) : AC(132), Delta-tetrahydrocannabinol (THC) : CK(391) : AC(90)

Diseases : Brachial Plexus Neuropathies : CK(20) : AC(2), Neuropathic Pain : CK(157) : AC(24)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Cannabis may have therapeutic value in the treatment of Tourette syndrome.

Click here to read the entire abstract

Pubmed Data : Acta Psychiatr Scand. 1998 Dec;98(6):502-6. PMID: 9879795

Article Published Date : Dec 01, 1998

Study Type : Human Study

Additional Links

Substances : Cannabinoids : CK(195) : AC(53), Cannabis : CK(738) : AC(132)

Diseases : Obsessive-Compulsive Disorder : CK(823) : AC(22), Tourette Syndrome : CK(139) : AC(17)

Cannabis-based medicine is effective in reducing pain and sleep disturbance in patients with multiple sclerosis related central neuropathic pain and is mostly well tolerated.

Click here to read the entire abstract

Pubmed Data : Neurology. 2005 Sep 27;65(6):812-9. PMID: 16186518

Article Published Date : Sep 27, 2005

Study Type : Human Study

Additional Links

Substances : Cannabinoids : CK(195) : AC(53), Cannabis : CK(738) : AC(132)

Diseases : Insomnia : CK(471) : AC(56), Multiple Sclerosis : CK(716) : AC(133), Pain : CK(616) : AC(91), Sleep Disorders : CK(168) : AC(17)

Pharmacological Actions : Analgesics : CK(372) : AC(78)

Delta-tetrahydrocannabinol (THC) and cannabidiol have therapeutic value in the management of spasticity associated wtih multiple sclerosis.

Click here to read the entire abstract

Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 1996 Aug;42(4):325-37. PMID: 21456949

Article Published Date : Aug 01, 1996

Study Type : Human Study

Additional Links

Substances : Cannabidiol : CK(391) : AC(92), Delta-tetrahydrocannabinol (THC) : CK(391) : AC(90)

Diseases : Multiple Sclerosis : CK(716) : AC(133), Muscle Spasticity : CK(34) : AC(5)

Pharmacological Actions : Antispasmodic : CK(112) : AC(29)

Orally administered cannabis extract may provide a therapeutic option to other drugs in the treatment of spasticity in patients with multiple sclerosis

Click here to read the entire abstract

Pubmed Data : Mult Scler. 2004 Aug;10(4):417-24. PMID: 15327040

Article Published Date : Aug 01, 2004

Study Type : Human Study

Additional Links

Substances : Cannabidiol : CK(391) : AC(92)

Diseases : Multiple Sclerosis : CK(716) : AC(133), Muscle Spasticity : CK(34) : AC(5)

Cannabinoids inhibit glioma (brain cancer) through the down-regulation of Tissue Inhibitors of Metalloproteinases (TIMPs).

Click here to read the entire abstract

Pubmed Data : Neuropharmacology. 2008 Jan;54(1):235-43. Epub 2007 Jul 1. PMID: 17675107

Article Published Date : Jan 01, 2008

Study Type : Human: Case Report, In Vitro Study

Additional Links

Substances : Cannabinoids : CK(195) : AC(53), Marihuana : CK(727) : AC(139)

Diseases : Astrocytoma : CK(2) : AC(2), Astrocytoma: Grade IV : CK(3) : AC(1), Brain Cancer : CK(231) : AC(88), Glioma : CK(74) : AC(40)

Additional Keywords : Tissue Inhibitors of Metalloproteinases (TIMPs) : CK(3) : AC(1)

A cannabinoid CB2 receptor selective compound, delays disease progression in a mouse model of amyotrophic lateral sclerosis.

Click here to read the entire abstract

Pubmed Data : Eur J Pharmacol. 2006 Aug 7;542(1-3):100-5. Epub 2006 May 20. PMID: 16781706

Article Published Date : Aug 07, 2006

Study Type : Animal Study

Additional Links

Substances : Cannabinoids : CK(195) : AC(53)

Diseases : Amyotrophic Lateral Sclerosis : CK(350) : AC(68)

Pharmacological Actions : Neuroprotective Agents : CK(962) : AC(480)

Acute administration of cannabidiol in vivo suppresses ischaemia-induced cardiac arrhythmias and reduces infarct size when given at reperfusion.

Click here to read the entire abstract

Pubmed Data : Br J Pharmacol. 2010 Jul;160(5):1234-42. PMID: 20590615

Article Published Date : Jul 01, 2010

Study Type : Animal Study

Additional Links

Substances : Cannabidiol : CK(391) : AC(92), Cannabis : CK(738) : AC(132)

Diseases : Cardiac Arrhythmias : CK(461) : AC(65), Myocardial Infarction : CK(2632) : AC(117), Myocardial Ischemia : CK(87) : AC(37)

Pharmacological Actions : Cardioprotective : CK(702) : AC(196)

Cannabidiol attenuates cardiac dysfunction, oxidative stress, fibrosis, and inflammatory and cell death signaling pathways in diabetic cardiomyopathy.

Click here to read the entire abstract

Pubmed Data : J Am Coll Cardiol. 2010 Dec 14;56(25):2115-25. PMID: 21144973

Article Published Date : Dec 14, 2010

Study Type : Animal Study

Additional Links

Substances : Cannabidiol : CK(391) : AC(92)

Diseases : Cardiomyopathy : CK(77) : AC(15), Cardiovascular Diseases : CK(5138) : AC(641), Diabetes: Cardiovascular Illness : CK(666) : AC(104)

Cannabidiol attenuates delayed-type hypersensitivity reactions.

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Pubmed Data : Acta Pharmacol Sin. 2010 Dec;31(12):1611-7. Epub 2010 Nov 1. PMID: 21042286

Article Published Date : Dec 01, 2010

Study Type : Animal Study

Additional Links

Substances : Cannabidiol : CK(391) : AC(92)

Diseases : Hypersensitivity : CK(64) : AC(15), Hypersensitivity: Type IV : CK(2) : AC(1)

Cannabidiol exhibits therapeutic activity in a mouse model of obsessive-compulsive disorder.

Click here to read the entire abstract

Pubmed Data : Platelets. 2006 Feb;17(1):37-41. PMID: 20695034

Article Published Date : Feb 01, 2006

Study Type : Animal Study

Additional Links

Substances : Cannabidiol : CK(391) : AC(92), Cannabis : CK(738) : AC(132)

Diseases : Obsessive-Compulsive Disorder : CK(823) : AC(22)

Cannabidiol exhibits therapeutic potential against ischemia/reperfusion liver injury in rats.

Click here to read the entire abstract

Pubmed Data : Eur J Pharmacol. 2011 Nov 16 ;670(1):216-23. Epub 2011 Sep 14. PMID: 21930120

Article Published Date : Nov 16, 2011

Study Type : Animal Study

Additional Links

Substances : Cannabidiol : CK(391) : AC(92)

Diseases : Liver Damage : CK(597) : AC(213), Liver Injury: Ischemia/reperfusion : CK(2) : AC(1)

Pharmacological Actions : Hepatoprotective : CK(557) : AC(272)

Cannabidiol has a neuroprotective and blood-retinal-preserving effect in experimental diabetes.

Click here to read the entire abstract

Pubmed Data : Int Urol Nephrol. 2004;36(4):591-8. PMID: 16400026

Article Published Date : Jan 01, 2004

Study Type : Animal Study

Additional Links

Substances : Cannabidiol : CK(391) : AC(92)

Diseases : Diabetes: Cataract : CK(23) : AC(13), Diabetes Mellitus: Type 1 : CK(1107) : AC(218), Diabetes Mellitus: Type 2 : CK(3429) : AC(341), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Neuroprotective Agents : CK(962) : AC(480), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348), Vascular Endothelial Growth Factor A Inhibitor : CK(102) : AC(58)

Cannabidiol has a neuroprotective effect in endotoxin-induced uveitis.

Click here to read the entire abstract

Pubmed Data : Mol Vis. 2008;14:2190-203. Epub 2008 Dec 3. PMID: 19052649

Article Published Date : Jan 01, 2008

Study Type : Animal Study

Additional Links

Substances : Cannabidiol : CK(391) : AC(92), Cannabis : CK(738) : AC(132)

Diseases : Brain: Microglial Activation : CK(67) : AC(38), Endotoxemia : CK(187) : AC(40), Lipopolysaccharide-Induced Toxicity : CK(227) : AC(128), Oxidative Stress : CK(1945) : AC(710), Uveitis : CK(63) : AC(10)

Pharmacological Actions : Enzyme Inhibitors : CK(372) : AC(208), Neuroprotective Agents : CK(962) : AC(480), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)

Cannabidiol improves brain and liver function in a fulminant hepatic failure-induced model of hepatic encephalopathy in mice.

Click here to read the entire abstract

Pubmed Data : Br J Pharmacol. 2010 Dec 23. Epub 2010 Dec 23. PMID: 21182490

Article Published Date : Dec 23, 2010

Study Type : Animal Study

Additional Links

Substances : Cannabidiol : CK(391) : AC(92), Cannabis : CK(738) : AC(132)

Diseases : Fulminant Hepatic Failure : CK(8) : AC(2), Hepatic Encephalopathy : CK(44) : AC(9), Liver Failure: Acute : CK(8) : AC(2)

Pharmacological Actions : Hepatoprotective : CK(557) : AC(272), Neuroprotective Agents : CK(962) : AC(480)

Cannabidiol inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1.

Click here to read the entire abstract

Pubmed Data : FASEB J. 2012 Apr ;26(4):1535-48. Epub 2011 Dec 23. PMID: 22198381

Article Published Date : Apr 01, 2012

Study Type : Animal Study

Additional Links

Substances : Cannabidiol : CK(391) : AC(92)

Diseases : Cancer Metastasis : CK(272) : AC(135), Lung Cancer : CK(496) : AC(198)

Pharmacological Actions : Anti-metastatic : CK(192) : AC(115), Intracellular adhesion molecule-1 (ICAM-1) : CK(4) : AC(3)

Cannabidiol inhibits symptoms of multiple sclerosis-like disease in mice.

Click here to read the entire abstract

Pubmed Data : Br J Pharmacol. 2011 Mar 30. Epub 2011 Mar 30. PMID: 21449980

Article Published Date : Mar 30, 2011

Study Type : Animal Study

Additional Links

Substances : Cannabidiol : CK(391) : AC(92)

Diseases : Brain: Microglial Activation : CK(67) : AC(38), Multiple Sclerosis : CK(716) : AC(133)

Pharmacological Actions : Immunomodulatory : CK(536) : AC(142), Immunomodulatory: T-Cell down-regulation : CK(12) : AC(2)

Cannabidiol protects retinal neurons by preserving glutamine synthetase activity in diabetes.

Click here to read the entire abstract

Pubmed Data : Mol Vis. 2010;16:1487-95. Epub 2010 Aug 4. PMID: 20806080

Article Published Date : Jan 01, 2010

Study Type : Animal Study

Additional Links

Substances : Cannabidiol : CK(391) : AC(92), Cannabis : CK(738) : AC(132)

Diseases : Diabetes: Cataract : CK(23) : AC(13)

Cannabinoid potentiation of glycine receptors contributes to cannabis-induced analgesia.

Click here to read the entire abstract

Pubmed Data : Nat Chem Biol. 2011 May;7(5):296-303. Epub 2011 Apr 3. PMID: 21460829

Article Published Date : May 01, 2011

Study Type : Animal Study

Additional Links

Substances : Cannabinoids : CK(195) : AC(53)

Diseases : Pain : CK(616) : AC(91)

Pharmacological Actions : Analgesics : CK(372) : AC(78), Glycine Agents : CK(2) : AC(1)

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