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Capsaicin

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Article Count - 34
Cumulative Knowledge - 60

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View the Evidence: Substances

Curcumin and capsaicin might represent an alternative approach to protect against vitiligo progression.

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Pubmed Data : Antioxid Redox Signal. 2010 Jan 19. Epub 2010 Jan 19. PMID: 20085492

Article Published Date : Jan 19, 2010

Study Type : Human Study

Additional Links

Substances : Capsaicin : CK(60) : AC(34), Curcumin : CK(2910) : AC(1482)

Diseases : Vitiligo : CK(47) : AC(10)

"Antitumor activity of capsaicin on human colon cancer cells in vitro and colo 205 tumor xenografts in vivo.

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Pubmed Data : J Agric Food Chem. 2010 Dec 22 ;58(24):12999-3005. Epub 2010 Nov 17. PMID: 21082859

Article Published Date : Dec 21, 2010

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Capsaicin : CK(60) : AC(34)

Diseases : Colon Cancer : CK(895) : AC(233)

Pharmacological Actions : Apoptotic : CK(1489) : AC(1114)

"Antitumor activity of capsaicin on human colon cancer cells in vitro and colo 205 tumor xenografts in vivo."

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Pubmed Data : J Agric Food Chem. 2010 Dec 22 ;58(24):12999-3005. Epub 2010 Nov 17. PMID: 21082859

Article Published Date : Dec 21, 2010

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Capsaicin : CK(60) : AC(34)

Diseases : Colon Cancer : CK(895) : AC(233)

Pharmacological Actions : Apoptotic : CK(1489) : AC(1114)

"Apoptosis inhibition of capsaicin on myocardial ischemia-reperfusion injury in rats"

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Pubmed Data : Sichuan Da Xue Xue Bao Yi Xue Ban. 2011 Mar ;42(2):218-21. PMID: 21500557

Article Published Date : Feb 28, 2011

Study Type : Animal Study

Additional Links

Substances : Capsaicin : CK(60) : AC(34)

Diseases : Myocardial Infarction : CK(2632) : AC(117), Myocardial Ischemia : CK(87) : AC(37)

Pharmacological Actions : Anti-Apoptotic : CK(59) : AC(39), Cardioprotective : CK(702) : AC(196)

Capsaicin ameliorates oxidative stress mediated damage produced during benzo(a)pyrene-induced lung cancer.

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Pubmed Data : Phytother Res. 2008 Apr;22(4):529-33. PMID: 18338764

Article Published Date : Apr 01, 2008

Study Type : Animal Study

Additional Links

Substances : Capsaicin : CK(60) : AC(34)

Diseases : Benzo[a]pyrene-induced Toxicity : CK(62) : AC(33), Lung Cancer : CK(496) : AC(198), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

Capsaicin and curcumin lower levels of an arthritis-associated glycoprotein in the sera of rats.

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Pubmed Data : Mol Cell Biochem. 1997 Apr;169(1-2):125-34. PMID: 9089639

Article Published Date : Apr 01, 1997

Study Type : Animal Study

Additional Links

Substances : Capsaicin : CK(60) : AC(34), Curcumin : CK(2910) : AC(1482)

Diseases : Arthritis : CK(1430) : AC(218)

Capsaicin pretreatment attenuates chronic hypoxic pulmonary hypertension.

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Pubmed Data : Respir Physiol. 1995 Feb;99(2):283-9. PMID: 7539934

Article Published Date : Feb 01, 1995

Study Type : Animal Study

Additional Links

Substances : Capsaicin : CK(60) : AC(34)

Diseases : Hypertension : CK(2783) : AC(271), Hypertension: Pulmonary : CK(1830) : AC(34), Hypoxia : CK(100) : AC(41)

Curcumin and capsaicin exert anti-tumor promotional effects through suppression of the tumor promoter-induced activation.

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Pubmed Data : Biofactors. 2000;12(1-4):107-12. PMID: 11216470

Article Published Date : Jan 01, 2000

Study Type : Animal Study

Additional Links

Substances : Capsaicin : CK(60) : AC(34), Curcumin : CK(2910) : AC(1482)

Diseases : Tumors : CK(197) : AC(110)

Pharmacological Actions : Anticarcinogenic Agents : CK(521) : AC(275), NF-kappaB Inhibitor : CK(595) : AC(401), Oncogene Suppressor : CK(14) : AC(10)

Curcumin and capsaicin have hypolipidemic and antioxidant effects in high-fat-fed rats.

Click here to read the entire abstract

Pubmed Data : Can J Physiol Pharmacol. 2007 Jun;85(6):588-96. PMID: 17823620

Article Published Date : Jun 01, 2007

Study Type : Animal Study

Additional Links

Substances : Capsaicin : CK(60) : AC(34), Curcumin : CK(2910) : AC(1482)

Diseases : Hyperlipidemia : CK(1211) : AC(109), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Hypolipidemic : CK(370) : AC(80)

Curcumin and capsaicin individually are protective to LDL oxidation both in vivo and in vitro, to iron-induced hepatotoxicity and to carrageenan-induced inflammation.

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Pubmed Data : J Agric Food Chem. 2009 Aug 26;57(16):7401-8. PMID: 16956363

Article Published Date : Aug 26, 2009

Study Type : Animal Study

Additional Links

Substances : Capsaicin : CK(60) : AC(34), Curcumin : CK(2910) : AC(1482)

Diseases : Chemically-Induced Liver Damage : CK(475) : AC(175), Cholesterol: Oxidation : CK(457) : AC(98), Inflammation : CK(1077) : AC(363), Iron Poisoning : CK(22) : AC(10)

Pharmacological Actions : Hepatoprotective : CK(557) : AC(272)

Additional Keywords : Natural Substance Synergy : CK(144) : AC(81)

Curcumin, capsaicin and garlic attenuate adverse blood changes associated with a cholesterol-enriched diet.

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Pubmed Data : Br J Nutr. 2005 Jan;93(1):81-91. PMID: 15705229

Article Published Date : Jan 01, 2005

Study Type : Animal Study

Additional Links

Substances : Capsaicin : CK(60) : AC(34), Curcumin : CK(2910) : AC(1482), Garlic : CK(485) : AC(160)

Diseases : High Cholesterol : CK(1718) : AC(198)

Curcumin, capsaicin and garlic have a beneficial influence on erythrocyte integrity in high-fat fed rats.

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Pubmed Data : J Nutr Biochem. 2006 Jul;17(7):471-8. Epub 2005 Oct 25. PMID: 16263255

Article Published Date : Jul 01, 2006

Study Type : Animal Study

Additional Links

Substances : Capsaicin : CK(60) : AC(34), Curcumin : CK(2910) : AC(1482), Garlic : CK(485) : AC(160)

Diseases : Hyperlipidemia : CK(1211) : AC(109)

Pharmacological Actions : Hypolipidemic : CK(370) : AC(80)

Curcumin, capsaicin and garlic inhibit adverse blood and liver changes associated wtih a high-fat diet in rats.

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Pubmed Data : Ann Nutr Metab. 2004 Sep-Oct;48(5):314-20. Epub 2004 Oct 1. PMID: 15467281

Article Published Date : Sep 01, 2004

Study Type : Animal Study

Additional Links

Substances : Capsaicin : CK(60) : AC(34), Curcumin : CK(2910) : AC(1482), Garlic : CK(485) : AC(160)

Diseases : Hyperlipidemia : CK(1211) : AC(109), Liver Disease : CK(112) : AC(31), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Hepatoprotective : CK(557) : AC(272)

Curcumin, capsaicin and garlic reduce adverse changes in red blood cells associated with hypercholesterolemia.

Click here to read the entire abstract

Pubmed Data : Mol Cell Biochem. 2002 Jul;236(1-2):155-61. PMID: 12190115

Article Published Date : Jul 01, 2002

Study Type : Animal Study

Additional Links

Substances : Capsaicin : CK(60) : AC(34), Curcumin : CK(2910) : AC(1482), Garlic : CK(485) : AC(160)

Diseases : Hypercholesterolemia : CK(1517) : AC(165)

Pharmacological Actions : Cardioprotective : CK(702) : AC(196), Enzyme Inhibitors : CK(372) : AC(208)

Curcumin, capsaicin, and garlic have a beneficial effect in the red blood cells and liver of cholesterol fed rats.

Click here to read the entire abstract

Pubmed Data : Acta Pharmacol Sin. 2007 Oct;28(10):1559-65. PMID: 15296079

Article Published Date : Oct 01, 2007

Study Type : Animal Study

Additional Links

Substances : Capsaicin : CK(60) : AC(34), Curcumin : CK(2910) : AC(1482), Garlic : CK(485) : AC(160)

Diseases : High Cholesterol : CK(1718) : AC(198)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Cardioprotective : CK(702) : AC(196), Hepatoprotective : CK(557) : AC(272)

Dietary curcumin and capsaicin have hypolipidemic and antioxidant effects.

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Pubmed Data : Life Sci. 2001 Dec 7;70(3):253-67. PMID: 17960446

Article Published Date : Dec 07, 2001

Study Type : Animal Study

Additional Links

Substances : Capsaicin : CK(60) : AC(34), Curcumin : CK(2910) : AC(1482)

Diseases : High Cholesterol : CK(1718) : AC(198)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Hypolipidemic : CK(370) : AC(80)

Dietary ginger and other spice compounds enhance fat digestion and absorption in high-fat fed situation through enhanced secretion of bile salts and a stimulation of the activity pancreatic lipase.

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Pubmed Data : J Sci Food Agric. 2011 Sep 14. Epub 2011 Sep 14. PMID: 21918995

Article Published Date : Sep 13, 2011

Study Type : Animal Study

Additional Links

Substances : Capsaicin : CK(60) : AC(34), Ginger : CK(310) : AC(89), Piperine : CK(29) : AC(14)

Diseases : Fat Malabsorption : CK(2) : AC(1), Indigestion: Fats : CK(2) : AC(1), Steatorrhea : CK(12) : AC(2)

Pharmacological Actions : Enzyme Inhibitors: Pancreatic Lipase : CK(12) : AC(2)

Dietary spices have a beneficial effect on intestinal villi by increasing the absorptive surface of the small intestine, providing for an increased bioavailability of micronutrients.

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Pubmed Data : Br J Nutr. 2010 Feb 24:1-9. Epub 2010 Feb 24. PMID: 20178671

Article Published Date : Feb 24, 2010

Study Type : Animal Study

Additional Links

Substances : Black Pepper : CK(88) : AC(35), Capsaicin : CK(60) : AC(34), Ginger : CK(310) : AC(89), Piperine : CK(29) : AC(14), Red Pepper : CK(4) : AC(2)

Diseases : Malabsorption Syndrome : CK(34) : AC(11), Microvilli atrophy : CK(4) : AC(1)

Additional Keywords : Nutrient Absorption : CK(4) : AC(2)

"Capsaicin induces apoptosis of cisplatin-resistant stomach cancer cells by causing degradation of cisplatin-inducible Aurora-A protein."

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Pubmed Data : Nutr Cancer. 2011 ;63(7):1095-103. Epub 2011 Sep 20. PMID: 21932983

Article Published Date : Dec 31, 2010

Study Type : In Vitro Study

Additional Links

Substances : Capsaicin : CK(60) : AC(34)

Diseases : Cancers: Drug Resistant : CK(225) : AC(147), Chemotherapy-Induced Toxicity: Cisplatin : CK(172) : AC(66), Gastric Cancer : CK(373) : AC(111)

Pharmacological Actions : Antineoplastic Agents : CK(877) : AC(496), Apoptotic : CK(1489) : AC(1114), Chemosensitizer : CK(197) : AC(159), NF-kappaB Inhibitor : CK(595) : AC(401)

"Capsaicin induces cycle arrest by inhibiting cyclin-dependent-kinase in bladder carcinoma cells."

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Pubmed Data : Int J Urol. 2012 Jul ;19(7):662-8. Epub 2012 Mar 29. PMID: 22462738

Article Published Date : Jun 30, 2012

Study Type : In Vitro Study

Additional Links

Substances : Capsaicin : CK(60) : AC(34)

Diseases : Bladder Cancer : CK(186) : AC(60)

Pharmacological Actions : Antiproliferative : CK(1052) : AC(775), Apoptotic : CK(1489) : AC(1114)

"Capsaicin-induced apoptosis of FaDu human pharyngeal squamous carcinoma cells."

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Yonsei Med J. 2012 Jul 1 ;53(4):834-41. PMID: 22665354

Article Published Date : Jun 30, 2012

Study Type : In Vitro Study

Additional Links

Substances : Capsaicin : CK(60) : AC(34)

Diseases : Nasopharyngeal Cancer : CK(58) : AC(21), Squamous cell carcinoma : CK(79) : AC(36)

Pharmacological Actions : Antiproliferative : CK(1052) : AC(775), Apoptotic : CK(1489) : AC(1114), Bcl-2 protein down-regulation : CK(49) : AC(38), Cell cycle arrest : CK(390) : AC(319)

Capsaicin induces apoptosis in SCC-4 human tongue cancer cells.

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Pubmed Data : Environ Toxicol. 2012 May ;27(6):332-41. Epub 2010 Oct 5. PMID: 20925121

Article Published Date : Apr 30, 2012

Study Type : In Vitro Study

Additional Links

Substances : Capsaicin : CK(60) : AC(34)

Diseases : Tongue Cancer : CK(14) : AC(10)

Pharmacological Actions : Apoptotic : CK(1489) : AC(1114), Cell cycle arrest : CK(390) : AC(319)

Capsaicin induces programmed cell death in a human stomach cancer cell line.

Click here to read the entire abstract

Pubmed Data : Cancer Lett. 1997 Dec 9;120(2):235-41. PMID: 9461043

Article Published Date : Dec 09, 1997

Study Type : In Vitro Study

Additional Links

Substances : Capsaicin : CK(60) : AC(34)

Diseases : Stomach Cancer : CK(373) : AC(20)

Pharmacological Actions : Apoptotic : CK(1489) : AC(1114)

Capsaicin inhibits growth of adult T-cell leukemia cells.

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Pubmed Data : Leuk Res. 2003 Mar;27(3):275-83. PMID: 12537981

Article Published Date : Mar 01, 2003

Study Type : In Vitro Study

Additional Links

Substances : Capsaicin : CK(60) : AC(34)

Diseases : Adult T-cell leukemia/lymphoma (ATL) : CK(53) : AC(6)

Pharmacological Actions : NF-kappaB Inhibitor : CK(595) : AC(401)

Capsaicin is a novel chemopreventive molecule.

Click here to read the entire abstract

Pubmed Data : Indian J Cancer. 2010 Jan-Mar;47(1):53-8. PMID: 20071791

Article Published Date : Jan 01, 2010

Study Type : Commentary

Additional Links

Substances : Capsaicin : CK(60) : AC(34)

Diseases : Cancers: All : CK(9062) : AC(2869)

Pharmacological Actions : Apoptotic : CK(1489) : AC(1114), Cell cycle arrest : CK(390) : AC(319), Chemopreventive : CK(1528) : AC(382), Cyclooxygenase 2 Inhibitors : CK(269) : AC(169), NF-kappaB Inhibitor : CK(595) : AC(401)

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