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Citrulline
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Additional Topics Details for this Page
Article Count
- 14
Cumulative Knowledge
- 92
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Quick Summary: Current access displays 2 out of 16 associated Diseases
Name
Cumulative Knowledge
Article Count
Focus Articles
Heart Failure
20
2
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Hypertension
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Quick Summary: 2 associated Pharmacological Actions
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Nitric Oxide Enhancer
12
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Cardiotonic Agents
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View the Evidence: Substances
Administration of L-arginine and citrulline to patients improve the condition of heart failure patients with preserved ejection fraction.
Click here to read the entire abstract
Pubmed Data
: Cardiol J. 2010;17(6):612-8. PMID:
21154265
Article Published Date
: Jan 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Arginine : CK(970) : AC(169)
,
Citrulline : CK(82) : AC(14)
Diseases
:
Heart Failure : CK(711) : AC(97)
,
Hypertension : CK(2783) : AC(271)
Pharmacological Actions
:
Cardiotonic Agents : CK(46) : AC(7)
Citrulline and spirulina may have a therapeutic role in the management of sickle cell disease.
Click here to read the entire abstract
Pubmed Data
: Cancer Res. 2006 Oct 15;66(20):10064-72. PMID:
20089363
Article Published Date
: Oct 15, 2006
Study Type
: Human Study
Additional Links
Substances
:
Citrulline : CK(82) : AC(14)
,
Spirulina : CK(75) : AC(21)
Diseases
:
Anemia: Sickle Cell : CK(136) : AC(5)
Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness.
Click here to read the entire abstract
Pubmed Data
: J Strength Cond Res. 2010 May;24(5):1215-22. PMID:
20386132
Article Published Date
: May 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Citrulline : CK(82) : AC(14)
Diseases
:
Athletic Performance : CK(479) : AC(61)
,
Athletic Performance: Recovery : CK(160) : AC(16)
,
Muscle Soreness: Exercise-Induced : CK(114) : AC(13)
Improvement of ventricular function in systolic heart failure patients with oral L-citrulline supplementation.
Click here to read the entire abstract
Pubmed Data
: Cardiol J. 2012 ;19(6):612-7. PMID:
23224924
Article Published Date
: Dec 31, 2011
Study Type
: Human Study
Additional Links
Substances
:
Citrulline : CK(82) : AC(14)
Diseases
:
Heart Failure : CK(711) : AC(97)
,
Left Ventricular Dysfunction : CK(65) : AC(9)
Oral L-citrulline supplementation attenuates blood pressure response to cold pressor test in young men.
Click here to read the entire abstract
Pubmed Data
: Am J Hypertens. 2010 Jan;23(1):12-6. Epub 2009 Oct 22. PMID:
19851298
Article Published Date
: Jan 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Citrulline : CK(82) : AC(14)
Diseases
:
Hypertension : CK(2783) : AC(271)
Oral L-citrulline supplementation improves erection hardness in men with mild erectile dysfunction.
Click here to read the entire abstract
Pubmed Data
: Urology. 2011 Jan;77(1):119-22. PMID:
21195829
Article Published Date
: Jan 01, 2011
Study Type
: Human Study
Additional Links
Substances
:
Citrulline : CK(82) : AC(14)
Diseases
:
Erectile Dysfunction : CK(510) : AC(41)
Short-term l-citrulline supplementation may functionally improve arterial stiffness, independent of blood pressure, in humans.
Click here to read the entire abstract
Pubmed Data
: Int J Cardiol. 2010 Nov 8. Epub 2010 Nov 8. PMID:
21067832
Article Published Date
: Nov 08, 2010
Study Type
: Human Study
Additional Links
Substances
:
Citrulline : CK(82) : AC(14)
Diseases
:
Arterial Hardening: Elasticity : CK(128) : AC(17)
Pharmacological Actions
:
Nitric Oxide Enhancer : CK(149) : AC(37)
The administration of L-arginine and citrulline has a beneficial effect on endothelial function in the treatment of heart failure.
Click here to read the entire abstract
Pubmed Data
: Cardiol J. 2010;17(5):464-70. PMID:
20865676
Article Published Date
: Jan 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Arginine : CK(970) : AC(169)
,
Citrulline : CK(82) : AC(14)
Diseases
:
Endothelial Dysfunction : CK(897) : AC(173)
,
Heart Failure : CK(711) : AC(97)
Citrulline increases protein synthesis and protein content in the muscle in old malnourished rats.
Click here to read the entire abstract
Pubmed Data
: Am J Physiol Endocrinol Metab. 2006 Sep;291(3):E582-6. Epub 2006 Apr 11. PMID:
16608884
Article Published Date
: Sep 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Citrulline : CK(82) : AC(14)
Diseases
:
Sarcopenia : CK(29) : AC(7)
Additional Keywords
:
Anabolic : CK(2) : AC(1)
,
Protein Energ Malnutrition : CK(2) : AC(1)
Citrulline malate has a beneficial effect on skeletal muscle function in the endotoxemic rat.
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2009 Jan 5;602(1):143-7. Epub 2008 Nov 17. PMID:
19036344
Article Published Date
: Jan 05, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Citrulline : CK(82) : AC(14)
Diseases
:
Endotoxemia : CK(187) : AC(40)
,
Klebsiella Infections : CK(59) : AC(22)
Citrulline/malate promotes aerobic energy production in human exercising muscle.
Click here to read the entire abstract
Pubmed Data
: Br J Sports Med. 2002 Aug;36(4):282-9. PMID:
12145119
Article Published Date
: Aug 01, 2002
Study Type
: Animal Study
Additional Links
Substances
:
Citrulline : CK(82) : AC(14)
Diseases
:
Athletic Performance : CK(479) : AC(61)
,
Mitochondrial Dysfunction : CK(149) : AC(51)
L-Citrulline ameliorates chronic hypoxia-induced pulmonary hypertension in newborn piglets.
Click here to read the entire abstract
Pubmed Data
: Am J Physiol Lung Cell Mol Physiol. 2009 Sep;297(3):L506-11. Epub 2009 Jul 17. PMID:
19617312
Article Published Date
: Sep 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Citrulline : CK(82) : AC(14)
Diseases
:
Hypertension: Pulmonary : CK(1830) : AC(34)
,
Hypoxia : CK(100) : AC(41)
Pharmacological Actions
:
Nitric Oxide Enhancer : CK(149) : AC(37)
The consumption of watermelon (a rich source of citrulline) results in elevated plasma arginine levels.
Click here to read the entire abstract
Pubmed Data
: Nutrition. 2007 Mar;23(3):261-6. PMID:
17352962
Article Published Date
: Mar 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Citrulline : CK(82) : AC(14)
,
Watermelon : CK(48) : AC(9)
Watermelon pomace (rich in citrulline) significantly ameliorates the metabolic syndrome in diabetic fatty rats.
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2007 Dec;137(12):2680-5. PMID:
18029483
Article Published Date
: Dec 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Citrulline : CK(82) : AC(14)
,
Watermelon : CK(48) : AC(9)
Diseases
:
Metabolic Syndrome X : CK(645) : AC(122)
Citrulline improves nitric oxide synthesis and improves cardiovascular function in a sustainable way.
Click here to read the entire abstract
Pubmed Data
: Curr Pharm Biotechnol. 2010 Dec;11(8):794-800. PMID:
17214603
Article Published Date
: Dec 01, 2010
Additional Links
Substances
:
Citrulline : CK(82) : AC(14)
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