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Cruciferous Vegetables

Cruciferous Vegetables

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Article Count - 232
Cumulative Knowledge - 643

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Quick Summary: Current access displays 2 out of 173 associated Diseases

Name	Cumulative Knowledge	Article Count	Focus Articles
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View the Evidence: Substances

Cabbage and brussel sprouts act bifunctionally, like an antiestrogen at low concentrations and an estrogen agonist at high concentrations.

Click here to read the entire abstract

Pubmed Data : J Agric Food Chem. 2000 Oct;48(10):4628-34. PMID: 11052710

Article Published Date : Oct 01, 2000

Study Type : In Vitro Study

Additional Links

Substances : Brussel sprouts : CK(17) : AC(6), Cabbage : CK(65) : AC(13)

Diseases : Estrogen Dominance : CK(106) : AC(37)

Cauliflower leaf protects against stannous chloride (tin)-induced cytotoxicity.

Click here to read the entire abstract

Pubmed Data : Food Chem Toxicol. 2002 Jul;40(7):919-23. PMID: 12065213

Article Published Date : Jul 01, 2002

Study Type : In Vitro Study

Additional Links

Substances : Cauliflower : CK(1) : AC(1)

Diseases : Tin Poisoning : CK(11) : AC(7)

Collard greens, kale and Chinese broccoli have a wide range of phenolic components.

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Pubmed Data : J Agric Food Chem. 2009 Aug 26;57(16):7401-8. PMID: 19627150

Article Published Date : Aug 26, 2009

Study Type : In Vitro Study

Additional Links

Substances : Broccoli : CK(449) : AC(185), Collards : CK(53) : AC(6), Flavonoids : CK(909) : AC(289), Kale : CK(43) : AC(6)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Combination treatment with resveratrol and sulforaphane induces programmed cell death in human glioma cells.

Click here to read the entire abstract

Pubmed Data : Neurochem Res. 2010 Jan;35(1):152-61. Epub 2009 Aug 15. PMID: 19685289

Article Published Date : Jan 01, 2010

Study Type : In Vitro Study

Additional Links

Substances : Resveratrol : CK(977) : AC(590), Sulforaphane : CK(520) : AC(171)

Pharmacological Actions : Antiproliferative : CK(1052) : AC(775), Apoptotic : CK(1489) : AC(1114), Cell cycle arrest : CK(390) : AC(319)

Additional Keywords : Stilbenes : CK(402) : AC(242)

Dietary sulforaphane is a histone deacetylase inhibitor for cancer prevention.

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Pubmed Data : J Nutr. 2009 Dec;139(12):2393-6. Epub 2009 Oct 7. PMID: 19812222

Article Published Date : Dec 01, 2009

Study Type : In Vitro Study

Additional Links

Substances : Sulforaphane : CK(520) : AC(171)

Diseases : Prostate Cancer : CK(998) : AC(288)

Pharmacological Actions : Anticarcinogenic Agents : CK(521) : AC(275), Enzyme Inhibitors : CK(372) : AC(208), Histone deacetylase inhibitor : CK(26) : AC(16)

DIM (3,3'-diindolylmethane) sensitizes breast tumors to chemotherapy.

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Pubmed Data : Mol Cancer Ther. 2007 Oct;6(10):2757-65. Epub 2007 Oct 3. PMID: 17913854

Article Published Date : Oct 01, 2007

Study Type : In Vitro Study

Additional Links

Substances : DIM (3,3'-diindolylmethane) : CK(17) : AC(6)

Diseases : Breast Cancer : CK(2354) : AC(621)

Pharmacological Actions : Chemosensitizer : CK(197) : AC(159)

Additional Keywords : Drug-Plant-Vitamin Synergies : CK(1011) : AC(268)

DIM inhibits prostate cancer cell growth.

Click here to read the entire abstract

Pubmed Data : Carcinogenesis. 2000 May;21(5):921-7. PMID: 17047070

Article Published Date : May 01, 2000

Study Type : In Vitro Study

Additional Links

Substances : DIM (3,3'-diindolylmethane) : CK(17) : AC(6)

Diseases : Prostate Cancer : CK(998) : AC(288)

Indole-3 carbinol and genistein inhibit a transcription factor required for pancreatic cancer cell proliferation and differentiation.

Click here to read the entire abstract

Pubmed Data : Anticancer Res. 2004 Jan-Feb;24(1):133-7. PMID: 15015587

Article Published Date : Jan 01, 2004

Study Type : In Vitro Study

Additional Links

Substances : Genistein : CK(450) : AC(174), Indole-3-Carbinol : CK(32) : AC(16)

Diseases : Pancreatic Cancer : CK(530) : AC(168)

Indole-3 carbinol increases the antibacterial activity of ampicillin against drug-resistant isolates of Gram-positive bacteria.

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Pubmed Data : Life Sci. 2010 Apr 24. Epub 2010 Apr 24. PMID: 18758080

Article Published Date : Apr 24, 2010

Study Type : In Vitro Study

Additional Links

Substances : Indole-3-Carbinol : CK(32) : AC(16)

Diseases : Gram-Positive Bacterial Infections : CK(13) : AC(12)

Additional Keywords : Antibiotic Resistance : CK(56) : AC(7), Drug-Plant-Vitamin Synergies : CK(1011) : AC(268)

Indole-3 carbinol is a negative regulator of estrogen.

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Pubmed Data : J Nutr. 2003 Jul;133(7 Suppl):2470S-2475S. PMID: 12840226

Article Published Date : Jul 01, 2003

Study Type : Commentary

Additional Links

Substances : Indole-3-Carbinol : CK(32) : AC(16)

Diseases : Estrogen Dominance : CK(106) : AC(37)

Indole-3 carbinol prevents cervical cancer by having an anti-estrogenic effect.

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Pubmed Data : Anticancer Res. 1999 May-Jun;19(3A):1673-80. PMID: 10470100

Article Published Date : May 01, 1999

Study Type : In Vitro Study

Additional Links

Substances : Indole-3-Carbinol : CK(32) : AC(16)

Diseases : Cervical Cancer : CK(363) : AC(69)

Indole-3-carbinol (I3C) induced cell growth inhibition, G1 cell cycle arrest and programmed cell death in prostate cancer cells.

Click here to read the entire abstract

Pubmed Data : Oncogene. 2001 May 24;20(23):2927-36. PMID: 11420705

Article Published Date : May 24, 2001

Study Type : In Vitro Study

Additional Links

Substances : Indole-3-Carbinol : CK(32) : AC(16)

Diseases : Prostate Cancer : CK(998) : AC(288)

Pharmacological Actions : Anticarcinogenic Agents : CK(521) : AC(275), Antiproliferative : CK(1052) : AC(775), Apoptotic : CK(1489) : AC(1114), NF-kappaB Inhibitor : CK(595) : AC(401), Tumor Suppressor Protein p53 Upregulation : CK(146) : AC(105)

Indole-3-carbinol enhances ultraviolet B-induced programmed cell death by sensitizing human melanoma cells.

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Pubmed Data : Cell Mol Life Sci. 2006 Nov;63(22):2661-8. PMID: 17086378

Article Published Date : Nov 01, 2006

Study Type : In Vitro Study

Additional Links

Substances : Indole-3-Carbinol : CK(32) : AC(16)

Diseases : Melanoma : CK(171) : AC(87)

Therapeutic Actions : Light Therapy : CK(69) : AC(19)

Pharmacological Actions : Apoptotic : CK(1489) : AC(1114)

Indole-3-carbinol exhibits selective cytotoxicity against a human breast tumor cell line.

Click here to read the entire abstract

Pubmed Data : J Agric Food Chem. 2008 Nov 26;56(22):10544-51. PMID: 12479697

Article Published Date : Nov 26, 2008

Study Type : In Vitro Study

Additional Links

Substances : Indole-3-Carbinol : CK(32) : AC(16)

Diseases : Breast Cancer : CK(2354) : AC(621)

Pharmacological Actions : Anticarcinogenic Agents : CK(521) : AC(275), Antiproliferative : CK(1052) : AC(775), Apoptotic : CK(1489) : AC(1114), NF-kappaB Inhibitor : CK(595) : AC(401)

Additional Keywords : Selective Cytotoxicity : CK(58) : AC(41)

Indole-3-carbinol has considerable antimicrobial activity against Candida albicans.

Click here to read the entire abstract

Pubmed Data : Yao Xue Xue Bao. 2008 Feb;43(2):128-32. PMID: 17917252

Article Published Date : Feb 01, 2008

Study Type : In Vitro Study

Additional Links

Substances : Indole-3-Carbinol : CK(32) : AC(16)

Diseases : Candida Infection : CK(211) : AC(96)

Pharmacological Actions : Antifungal Agents : CK(178) : AC(111)

Indole-3-carbinol inhibits androgen-responsive human prostate cancer cells.

Click here to read the entire abstract

Pubmed Data : Carcinogenesis. 2005 Nov;26(11):1896-904. Epub 2005 Jun 15. PMID: 15958518

Article Published Date : Nov 01, 2005

Study Type : In Vitro Study

Additional Links

Substances : Indole-3-Carbinol : CK(32) : AC(16)

Diseases : Prostate Cancer : CK(998) : AC(288)

Additional Keywords : Androgen Responsive Prostate Cancer : CK(1) : AC(1)

Mustard Greens (B. juncea) protect against oxidative stress in diabetic rats. - Article 2

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2003 May;17(5):465-71. PMID: 12748980

Article Published Date : May 01, 2003

Study Type : In Vitro Study

Additional Links

Substances : Mustard Greens : CK(39) : AC(12)

Diseases : Diabetes: Oxidative Stress : CK(65) : AC(18), Oxidative Stress : CK(1945) : AC(710)

Mustard sprouts and their juice inhibit benzo(a)pyrene-induced DNA damage in human cells and may have chemopreventive properties that can not be explained solely in terms of ally isothiocyante content.

Click here to read the entire abstract

Pubmed Data : Teratog Carcinog Mutagen. 2003;Suppl 1:273-82. PMID: 12616618

Article Published Date : Jan 01, 2003

Study Type : In Vitro Study

Additional Links

Substances : Mustard Greens : CK(39) : AC(12), Sprouts : CK(76) : AC(36)

Diseases : Benzo[a]pyrene-induced Toxicity : CK(62) : AC(33), DNA damage : CK(711) : AC(293), Liver Cancer : CK(1641) : AC(266)

Pharmacological Actions : Anticarcinogenic Agents : CK(521) : AC(275), Chemopreventive : CK(1528) : AC(382)

Additional Keywords : Isothiocyanates : CK(70) : AC(23), Plant Extracts : CK(3572) : AC(1216)

Noni contains an anthraquinone with potent quinone reductase-inducing (i.e. detoxifying) activity 40 times more potent than sufloraphane.

Click here to read the entire abstract

Pubmed Data : Rejuvenation Res. 2010 Dec;13(6):749-54. PMID: 16378361

Article Published Date : Dec 01, 2010

Study Type : In Vitro Study

Additional Links

Substances : Noni : CK(83) : AC(42), Sulforaphane : CK(520) : AC(171)

Pharmacological Actions : Anticarcinogenic Agents : CK(521) : AC(275), Quinone Reductase-Inducer : CK(3) : AC(2)

Phenethyl isothiocyanate and sulforaphane or curcumin and sulforaphane have a synergistic effect in the inhibition of inflammation.

Click here to read the entire abstract

Pubmed Data : Pharm Res. 2009 Jan;26(1):224-31. Epub 2008 Oct 8. PMID: 18841446

Article Published Date : Jan 01, 2009

Study Type : In Vitro Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482), Phenethyl isothiocyanate : CK(8) : AC(5), Sulforaphane : CK(520) : AC(171)

Diseases : Inflammation : CK(1077) : AC(363), Lipopolysaccharide-Induced Toxicity : CK(227) : AC(128)

Pharmacological Actions : Anticarcinogenic Agents : CK(521) : AC(275), Cyclooxygenase 2 Inhibitors : CK(269) : AC(169), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)

Additional Keywords : Isothiocyanates : CK(70) : AC(23), Natural Substance Synergy : CK(144) : AC(81)

Phytochemicals found in Cruciferous vegetables, glucosinolates, can exert protective and toxic effects against leukemic cell growth.

Click here to read the entire abstract

Pubmed Data : Carcinogenesis. 2002 Apr;23(4):581-6. PMID: 11960909

Article Published Date : Apr 01, 2002

Study Type : In Vitro Study

Additional Links

Substances : Cruciferous Vegetables : CK(622) : AC(232)

Diseases : Leukemia : CK(670) : AC(258)

Sufloraphane reduces doxorubicin resistance.

Click here to read the entire abstract

Pubmed Data : Mutat Res. 2006 Oct 10;601(1-2):92-101. Epub 2006 Jul 14. PMID: 16843502

Article Published Date : Oct 10, 2006

Study Type : In Vitro Study

Additional Links

Substances : Sulforaphane : CK(520) : AC(171)

Diseases : Cancers: Drug Resistant : CK(225) : AC(147)

Pharmacological Actions : Anticarcinogenic Agents : CK(521) : AC(275), Apoptotic : CK(1489) : AC(1114), Chemosensitizer : CK(197) : AC(159), Tumor Suppressor Protein p53 Upregulation : CK(146) : AC(105)

Additional Keywords : Drug: Doxorubicin : CK(141) : AC(55), Drug-Plant-Vitamin Synergies : CK(1011) : AC(268)

Sulforaphane activates progammed cell death in human glioblastoma cells.

Click here to read the entire abstract

Pubmed Data : Neuroscience. 2006 Sep 1;141(3):1265-80. Epub 2006 Jun 12. PMID: 16765523

Article Published Date : Sep 01, 2006

Study Type : In Vitro Study

Additional Links

Substances : Sulforaphane : CK(520) : AC(171)

Diseases : Brain Cancer : CK(231) : AC(88), Glioblastoma : CK(46) : AC(20)

Pharmacological Actions : Apoptotic : CK(1489) : AC(1114)

Sulforaphane activates programmed cell death pathways in human colon cancer cells.

Click here to read the entire abstract

Pubmed Data : Food Chem Toxicol. 2009 Sep;47(9):2366-73. Epub 2009 Jun 27. PMID: 19563859

Article Published Date : Sep 01, 2009

Study Type : In Vitro Study

Additional Links

Substances : Sulforaphane : CK(520) : AC(171)

Diseases : Colon Cancer : CK(895) : AC(233), DNA damage : CK(711) : AC(293), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Anticarcinogenic Agents : CK(521) : AC(275), Apoptotic : CK(1489) : AC(1114), Tumor Suppressor Protein p53 Upregulation : CK(146) : AC(105)

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