Curcuminoids

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View the Evidence: Substances

A combination of Saw Palmetto, Nettle, Curcumin and Quercetin significantly improves treatment outcome of prulifloxacin in bacterial prostatitis patients.

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Pubmed Data : Int J Antimicrob Agents. 2009 Jun;33(6):549-53. Epub 2009 Jan 31. PMID: 19181486

Article Published Date : Jun 01, 2009

Study Type : Human Study

Additional Links

Substances : Curcumin : CK(2890) : AC(1511), Nettle : CK(44) : AC(13), Quercetin : CK(315) : AC(136), Saw Palmetto : CK(82) : AC(17)

Diseases : Prostatitis: Chronic : CK(327) : AC(11)

Additional Keywords : Drug-Plant-Vitamin Synergies : CK(1011) : AC(268)

A complex of curcumin and phosphatidylcholine is effective in reducing the symptoms of ostearthritis.

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Pubmed Data : Altern Med Rev. 2010 Dec;15(4):337-44. PMID: 21194249

Article Published Date : Dec 01, 2010

Study Type : Human Study

Additional Links

Substances : Curcumin : CK(2890) : AC(1511), Phosphatidylcholine : CK(99) : AC(21)

Diseases : Osteoarthritis : CK(615) : AC(89)

Pharmacological Actions : Anti-Inflammatory Agents : CK(1144) : AC(420)

A daily dose of 3.6 g curcumin achieves pharmacologically efficacious levels in the colorectum with negligible distribution of curcumin outside the gut.

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Pubmed Data : Cancer Epidemiol Biomarkers Prev. 2005 Jan;14(1):120-5. PMID: 15668484

Article Published Date : Jan 01, 2005

Study Type : Human Study

Additional Links

Substances : Curcumin : CK(2890) : AC(1511)

Diseases : Colorectal Cancer : CK(809) : AC(303)

Pharmacological Actions : Chemopreventive : CK(1314) : AC(355), Cyclooxygenase 2 Inhibitors : CK(274) : AC(169)

Additional Keywords : Antineoplastic Agents : CK(69) : AC(28)

A standardized preparation of curcuminoids compares favorably with atorvastatin on endothelial dysfunction in association with reductions in inflammatory cytokines and markers of oxidative stress.

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Pubmed Data : Drugs R D. 2008;9(4):243-50. PMID: 18588355

Article Published Date : Jan 01, 2008

Study Type : Human Study

Additional Links

Substances : Curcumin : CK(2890) : AC(1511)

Diseases : Endothelial Dysfunction : CK(875) : AC(173), Inflammation : CK(994) : AC(348), Oxidative Stress : CK(1867) : AC(710)

Pharmacological Actions : Interleukin-6 Downregulation : CK(500) : AC(137), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(1015) : AC(343)

Additional Keywords : Drug: Atorvastatin : CK(10) : AC(1), Natural Substances Versus Drugs : CK(1043) : AC(159), Statin Alternatives : CK(34) : AC(4)

An exclusion diet and nutraceutical therapy has significant therapeutic effects in juvenile Crohn's disease.

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Pubmed Data : J Am Coll Nutr. 2009 Jun;28(3):277-85. PMID: 20150601

Article Published Date : Jun 01, 2009

Study Type : Human Study

Additional Links

Substances : Boswellia : CK(122) : AC(31), Colostrum : CK(59) : AC(11), Curcumin : CK(2890) : AC(1511), Fish extract : CK(32) : AC(4), Lactobacillus rhamnosus GG : CK(211) : AC(28), Multivitamin : CK(243) : AC(22)

Diseases : Crohn's Disease : CK(361) : AC(22)

Therapeutic Actions : Dietary Modification: Allergen Free Diet : CK(73) : AC(7)

Bioavailability Study: Piperine enhances the serum concentration, extent of absorption and bioavailability of curcumin in both rats and humans with no adverse effects.

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Pubmed Data : Planta Med. 1998 May;64(4):353-6. PMID: 9619120

Article Published Date : May 01, 1998

Study Type : Human Study

Additional Links

Substances : Curcumin : CK(2890) : AC(1511), Piperidines : CK(45) : AC(17)

Bioflavonoid therapy with curcumin and quercetin improves cadaveric renal transplantation in humans.

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Pubmed Data : Transplantation. 2005 Dec 15;80(11):1556-9. PMID: 16371925

Article Published Date : Dec 15, 2005

Study Type : Human Study

Additional Links

Substances : Bioflavonoids : CK(21) : AC(3), Curcumin : CK(2890) : AC(1511), Quercetin : CK(315) : AC(136)

Diseases : Organ Transplantation: Kidney : CK(80) : AC(8)

Chelidonium and turmeric root extract have a therapeutic effect on upper abdominal pain due to functional disorders of the biliary system.

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Pubmed Data : Med Klin (Munich). 1999 Aug 15;94(8):425-30. PMID: 10495621

Article Published Date : Aug 15, 1999

Study Type : Human Study

Additional Links

Substances : Chelidonium : CK(10) : AC(1), Curcumin : CK(2890) : AC(1511)

Diseases : Biliary Dyskinesia : CK(20) : AC(2), Cholestasis : CK(274) : AC(30), Dyspepsia : CK(422) : AC(21), Gallbladder Disease : CK(385) : AC(67)

Pharmacological Actions : Cholagogues and Choleretics : CK(51) : AC(10)

Additional Keywords : Plant Extracts : CK(3401) : AC(1158)

Curcumin acts as an adjuvant to imatinib in decreasing the NO levels and may help in the treatment of CML patients.

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Pubmed Data : J Oncol Pharm Pract. 2011 Aug 15. Epub 2011 Aug 15. PMID: 21844132

Article Published Date : Aug 15, 2011

Study Type : Human Study

Additional Links

Substances : Curcumin : CK(2890) : AC(1511), Turmeric : CK(2969) : AC(1565)

Diseases : Leukemia: Chronic myelogenous leukemia (CML) : CK(28) : AC(18)

Pharmacological Actions : Nitric Oxide Inhibitor : CK(108) : AC(57)

Additional Keywords : Drug: Imatinib : CK(10) : AC(1), Drug Synergy : CK(324) : AC(144)

Curcumin alleviates ethanol-induced oxidative damage in liver cells.

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Pubmed Data : J Ethnopharmacol. 2010 Jan 18. Epub 2010 Jan 18. PMID: 20080166

Article Published Date : Jan 18, 2010

Study Type : Human Study

Additional Links

Substances : Curcumin : CK(2890) : AC(1511)

Diseases : Alcohol Toxicity : CK(212) : AC(85), Alcoholic Liver Disease : CK(146) : AC(50)

Pharmacological Actions : Hepatoprotective : CK(534) : AC(261)

Curcumin and capsaicin might represent an alternative approach to protect against vitiligo progression.

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Pubmed Data : Antioxid Redox Signal. 2010 Jan 19. Epub 2010 Jan 19. PMID: 20085492

Article Published Date : Jan 19, 2010

Study Type : Human Study

Additional Links

Substances : Capsaicin : CK(47) : AC(25), Curcumin : CK(2890) : AC(1511)

Diseases : Vitiligo : CK(47) : AC(10)

Curcumin appears safe and effective in maintaining remission in patients with quiescent ulcerative colitis.

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Pubmed Data : Clin Gastroenterol Hepatol. 2006 Dec;4(12):1502-6. Epub 2006 Nov 13. PMID: 17101300

Article Published Date : Dec 01, 2006

Study Type : Human Study

Additional Links

Substances : Curcumin : CK(2890) : AC(1511)

Diseases : Ulcerative Colitis : CK(461) : AC(40)

Curcumin appears to enhance clearance of amyloid-beta in Alzheimer's disease patients.

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Pubmed Data : J Alzheimers Dis. 2006 Sep;10(1):1-7. PMID: 16988474

Article Published Date : Sep 01, 2006

Study Type : Human Study

Additional Links

Substances : Curcumin : CK(2890) : AC(1511)

Diseases : Alzheimer's Disease : CK(837) : AC(165)

Additional Keywords : Disease Regression : CK(138) : AC(20)

Curcumin compares favorably with corticosteroid therapy in the management of chronic anterior uveitis.

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Pubmed Data : Phytother Res. 1999 Jun;13(4):318-22. PMID: 10404539

Article Published Date : Jun 01, 1999

Study Type : Human Study

Additional Links

Substances : Curcumin : CK(2890) : AC(1511)

Diseases : Uveitis : CK(63) : AC(9)

Additional Keywords : Cortisone Alternatives : CK(79) : AC(12), Natural Substances Versus Drugs : CK(1043) : AC(159)

Curcumin exhibits anti-pre-cancer activity by increasing levels of vitamins C and E, and preventing lipid peroxidation and DNA damage.

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Pubmed Data : J Oral Sci. 2010;52(2):251-6. PMID: 20587949

Article Published Date : Jan 01, 2010

Study Type : Human Study

Additional Links

Substances : Curcumin : CK(2890) : AC(1511), Vitamin C : CK(1178) : AC(238), Vitamin E : CK(1290) : AC(218)

Diseases : DNA damage : CK(680) : AC(293), Leukoplakia : CK(31) : AC(4), Lichen Planus : CK(53) : AC(6), Oxidative Stress : CK(1867) : AC(710), Precancerous Conditions : CK(12) : AC(2)

Pharmacological Actions : Antioxidants : CK(3503) : AC(1292)

Curcumin has a contractive effect on human gallbladder function.

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Pubmed Data : J Bras Pneumol. 2006 Jan-Feb;32(1):66-74. PMID: 10102956

Article Published Date : Jan 01, 2006

Study Type : Human Study

Additional Links

Substances : Curcumin : CK(2890) : AC(1511)

Diseases : Cholestasis : CK(274) : AC(30)

Pharmacological Actions : Cholagogues and Choleretics : CK(51) : AC(10)

Curcumin has anti-inflammatory properties in patients with postoperative inflammation.

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Pubmed Data : Int J Clin Pharmacol Ther Toxicol. 1986 Dec;24(12):651-4. PMID: 3546166

Article Published Date : Dec 01, 1986

Study Type : Human Study

Additional Links

Substances : Curcumin : CK(2890) : AC(1511)

Diseases : Inflammation : CK(994) : AC(348), Postoperative Recovery : CK(100) : AC(9)

Pharmacological Actions : Anti-Inflammatory Agents : CK(1144) : AC(420)

Curcumin has gall-bladder emptying properties.

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Pubmed Data : Asia Pac J Clin Nutr. 2002;11(4):314-8. PMID: 12495265

Article Published Date : Jan 01, 2002

Study Type : Human Study

Additional Links

Substances : Curcumin : CK(2890) : AC(1511)

Diseases : Cholestasis : CK(274) : AC(30)

Therapeutic Actions : Fasting/Caloric Restriction : CK(225) : AC(50)

Pharmacological Actions : Cholagogues and Choleretics : CK(51) : AC(10)

Curcumin has potential in the treatment of plasma cell dyscrasias.

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Pubmed Data : Biologics. 2008 Mar;2(1):161-3. PMID: 19707439

Article Published Date : Mar 01, 2008

Study Type : Human Study

Additional Links

Substances : Curcumin : CK(2890) : AC(1511)

Diseases : Plasma Cell Dyscrasias : CK(10) : AC(1)

Curcumin has significant therapeutic activity in patients with pancreatic cancer.

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Pubmed Data : Clin Cancer Res. 2008 Jul 15;14(14):4491-9. PMID: 18628464

Article Published Date : Jul 15, 2008

Study Type : Human Study

Additional Links

Substances : Curcumin : CK(2890) : AC(1511)

Diseases : Pancreatic Cancer : CK(513) : AC(162)

Curcumin has therapeutic effects in idiopathic inflammatory orbital pseudotumours.

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Pubmed Data : Phytother Res. 2000 Sep;14(6):443-7. PMID: 10960899

Article Published Date : Sep 01, 2000

Study Type : Human Study

Additional Links

Substances : Curcumin : CK(2890) : AC(1511)

Diseases : Orbital Pseudotumor : CK(10) : AC(1)

Additional Keywords : Plant Extracts : CK(3401) : AC(1158)

Curcumin has therapeutic value in patients with monoclonal gammopathy, a possible precursor to multiple myeloma.

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Pubmed Data : Clin Cancer Res. 2009 Sep 15;15(18):5917-22. Epub 2009 Sep 8. PMID: 19737963

Article Published Date : Sep 15, 2009

Study Type : Human Study

Additional Links

Substances : Curcumin : CK(2890) : AC(1511)

Diseases : Monoclonal Gammopathies : CK(10) : AC(1), Multiple Myeloma : CK(136) : AC(51)

Curcumin has therapeutic value in the treatment of recurrent anterior uveitis of different etiologies.

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Pubmed Data : Clin Ophthalmol. 2010;4:1201-6. Epub 2010 Oct 21. PMID: 21060672

Article Published Date : Jan 01, 2010

Study Type : Human Study

Additional Links

Substances : Curcumin : CK(2890) : AC(1511)

Diseases : Diabetic Retinopathy : CK(24) : AC(10), Dry Eye Syndromes : CK(165) : AC(25), Eye Diseases : CK(689) : AC(139), Glaucoma : CK(123) : AC(19), Maculopathy : CK(10) : AC(1), Maculopathy: Age-Related : CK(37) : AC(7), Uveitis : CK(63) : AC(9)

Curcumin improves ulcerative proctitis and Crohn's disease in patient s with inflammatory bowel disease.

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Pubmed Data : Dig Dis Sci. 2005 Nov;50(11):2191-3. PMID: 16240238

Article Published Date : Nov 01, 2005

Study Type : Human Study

Additional Links

Substances : Curcumin : CK(2890) : AC(1511)

Diseases : Inflammatory Bowel Diseases : CK(1210) : AC(109), Proctitis : CK(10) : AC(1), Proctocolitis: Ulcerative : CK(30) : AC(3)

Pharmacological Actions : Anti-Inflammatory Agents : CK(1144) : AC(420)

Curcumin induces programmed cell death and inhibits proinflammatory prostaglandin E2 production in synovial fibroblasts of patients with rheumatoid arthritis.

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Pubmed Data : Int J Mol Med. 2007 Sep;20(3):365-72. PMID: 17671742

Article Published Date : Sep 01, 2007

Study Type : Human Study

Additional Links

Substances : Curcumin : CK(2890) : AC(1511)

Diseases : Arthritis: Rheumatoid : CK(289) : AC(54), Rheumatoid Arthritis : CK(413) : AC(62)

Pharmacological Actions : Anti-Inflammatory Agents : CK(1144) : AC(420)

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