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Ellagic Acid

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Article Count - 40
Cumulative Knowledge - 75

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View the Evidence: Substances

Ellagic acid significantly decreases the level of melanin in patients with melasma.

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Pubmed Data : J Dermatol. 2008 Sep;35(9):570-4. PMID: 18837701

Article Published Date : Sep 01, 2008

Study Type : Human Study

Additional Links

Substances : Ellagic Acid : CK(77) : AC(40)

Diseases : Melasma : CK(21) : AC(3)

Ellagic acid therapy reduces chemotherapy induced toxicity, e.g. neutropenia, in hormone refractory prostate cancer patients.

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Pubmed Data : Eur Urol. 2005 Apr;47(4):449-54; discussion 454-5. Epub 2005 Jan 19. PMID: 15774240

Article Published Date : Apr 01, 2005

Study Type : Human Study

Additional Links

Substances : Ellagic Acid : CK(77) : AC(40)

Diseases : Neutropenia: Chemotherapy Induced : CK(82) : AC(17), Prostate Cancer : CK(998) : AC(288)

Additional Keywords : Drug-Plant-Vitamin Synergies : CK(1011) : AC(268)

Berries and ellagic acid prevent estrogen-induced mammary tumorigenesis by modulating enzymes of estrogen metabolism.

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Pubmed Data : Cancer Prev Res (Phila Pa). 2010 Jun;3(6):727-37. Epub 2010 May 25. PMID: 20501861

Article Published Date : Jun 01, 2010

Study Type : Animal Study

Additional Links

Substances : Berries: All : CK(780) : AC(199), Blueberry : CK(140) : AC(39), Ellagic Acid : CK(77) : AC(40), Raspberry : CK(21) : AC(11)

Diseases : Breast Cancer : CK(2354) : AC(621), Estrogen Dominance : CK(106) : AC(37), Estrogen Dysregulation: 2/4/16 hydroxyestrone ratios : CK(40) : AC(9)

Pharmacological Actions : Chemopreventive : CK(1528) : AC(382), Estradiol Antagonists : CK(2) : AC(1)

Blueberry, black raspberry and ellagic acid significantly reduce tumor volume and multiplicity in estrogen-induced mammary carcinogenesis. - Article 1

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Pubmed Data : Acta Obstet Gynecol Scand. 2007 Jul 16:1-6. Epub 2007 Jul 16. PMID: 18444155

Article Published Date : Jul 16, 2007

Study Type : Animal Study

Additional Links

Substances : Black Raspberry : CK(4) : AC(2), Blueberry : CK(140) : AC(39), Ellagic Acid : CK(77) : AC(40)

Diseases : Breast Cancer : CK(2354) : AC(621)

Consumption of some polyphenols reduces fecal deoxycholic acid and lithocholic acid, the secondary bile acids of risk factors of colon cancer.

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Pubmed Data : J Agric Food Chem. 2009 Sep 23;57(18):8587-90. PMID: 19711910

Article Published Date : Sep 23, 2009

Study Type : Animal Study

Additional Links

Substances : Caffeic Acid : CK(15) : AC(11), Curcumin : CK(2910) : AC(1482), Ellagic Acid : CK(77) : AC(40), Flavonoids : CK(909) : AC(289), Polyphenols : CK(427) : AC(174), Rutin : CK(93) : AC(30)

Diseases : Colon Cancer : CK(895) : AC(233)

Pharmacological Actions : Anticarcinogenic Agents : CK(521) : AC(275)

Curcumin inhibits radiation-induced changes in the liver.

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Pubmed Data : J Radiol Prot. 2001 Dec;21(4):361-70. PMID: 11787891

Article Published Date : Dec 01, 2001

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482), Ellagic Acid : CK(77) : AC(40), Quercetin : CK(318) : AC(136)

Diseases : Radiation Induced Illness : CK(1018) : AC(249)

Pharmacological Actions : Hepatoprotective : CK(557) : AC(272), Protein Kinase Inhibitors : CK(15) : AC(11), Radioprotective : CK(456) : AC(183)

Curcumin, ellagic acid and bixin attenuate radiation induced toxicity.

Click here to read the entire abstract

Pubmed Data : Indian J Exp Biol. 1996 Sep;34(9):845-7. PMID: 9014516

Article Published Date : Sep 01, 1996

Study Type : Animal Study

Additional Links

Substances : Bixin : CK(7) : AC(4), Carotenoids : CK(1055) : AC(213), Curcumin : CK(2910) : AC(1482), Ellagic Acid : CK(77) : AC(40)

Diseases : Oxidative Stress : CK(1945) : AC(710), Radiation Induced Illness : CK(1018) : AC(249)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Radioprotective : CK(456) : AC(183)

Curcumin, ellagic acid and bixin provide protection against chromosome damage produced by radiation.

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Pubmed Data : J Exp Clin Cancer Res. 1998 Dec;17(4):431-4. PMID: 10089063

Article Published Date : Dec 01, 1998

Study Type : Animal Study

Additional Links

Substances : Bixin : CK(7) : AC(4), Carotenoids : CK(1055) : AC(213), Curcumin : CK(2910) : AC(1482), Ellagic Acid : CK(77) : AC(40)

Diseases : DNA damage : CK(711) : AC(293)

Pharmacological Actions : Radioprotective : CK(456) : AC(183)

Ellagic acid ameliorates nickel induced biochemical alterations: diminution of oxidative stress.

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Pubmed Data : Hum Exp Toxicol. 1999 Nov;18(11):691-8. PMID: 10602394

Article Published Date : Nov 01, 1999

Study Type : Animal Study

Additional Links

Substances : Ellagic Acid : CK(77) : AC(40)

Diseases : Chemically-Induced Liver Damage : CK(475) : AC(175), Nickel Poisoning : CK(9) : AC(5), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

Ellagic acid and pumpkin seed oil protects against methotrexate-induced small intestine damage in rats.

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Pubmed Data : Indian J Biochem Biophys. 2011 Dec ;48(6):380-7. PMID: 22329239

Article Published Date : Nov 30, 2011

Study Type : Animal Study

Additional Links

Substances : Ellagic Acid : CK(77) : AC(40), Pumpkin Seed Oil/Meal : CK(48) : AC(11)

Diseases : Drug Toxicity: Methotrexate : CK(30) : AC(13), Gastrointestinal Hemorrhage : CK(33) : AC(4)

Pharmacological Actions : Gastroprotective : CK(62) : AC(31)

Ellagic acid has anti-cataractogenic activity.

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Pubmed Data : Exp Eye Res. 2008 Feb;86(2):251-9. Epub 2007 Nov 5. PMID: 18068705

Article Published Date : Feb 01, 2008

Study Type : Animal Study

Additional Links

Substances : Ellagic Acid : CK(77) : AC(40)

Diseases : Cataract : CK(182) : AC(55)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

Additional Keywords : Sodium Selenite : CK(39) : AC(18)

Ellagic acid inhibits carbon tetrachloride induced liver toxicity and fibrosis.

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Pubmed Data : Indian J Physiol Pharmacol. 1996 Oct;40(4):363-6. PMID: 9055108

Article Published Date : Oct 01, 1996

Study Type : Animal Study

Additional Links

Substances : Ellagic Acid : CK(77) : AC(40)

Diseases : Chemically-Induced Liver Damage : CK(475) : AC(175), Liver Fibrosis : CK(341) : AC(74)

Pharmacological Actions : Hepatoprotective : CK(557) : AC(272)

Ellagic acid inhibits lung tumorigensis.

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Pubmed Data : Nutr Cancer. 1992;18(2):181-9. PMID: 1437655

Article Published Date : Jan 01, 1992

Study Type : Animal Study

Additional Links

Substances : Ellagic Acid : CK(77) : AC(40)

Diseases : Lung Cancer : CK(496) : AC(198)

Ellagic acid inhibits the development of pancreatic fibrosis in the rat experimental model.

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Pubmed Data : Dig Dis Sci. 2008 Jul 25. PMID: 18651219

Article Published Date : Jul 25, 2008

Study Type : Animal Study

Additional Links

Substances : Ellagic Acid : CK(77) : AC(40)

Diseases : Pancreatitis : CK(164) : AC(40)

Ellagic acid inhibits the gastric proton pumps, reducing acid secretion and the occurence of stress-induced gastric lesions.

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Pubmed Data : Mol Nutr Food Res. 2008 Jun;52(6):692-700. PMID: 1663631

Article Published Date : Jun 01, 2008

Study Type : Animal Study

Additional Links

Substances : Ellagic Acid : CK(77) : AC(40)

Diseases : Acid Reflux : CK(288) : AC(42), Gastric Ulcer : CK(246) : AC(91)

Pharmacological Actions : Anti-Ulcer Agents : CK(162) : AC(57), Proton Pump Inhibitor : CK(36) : AC(13)

Ellagic acid protects against cisplatin-induced kidney injury and oxidative stress in rats.

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Pubmed Data : Basic Clin Pharmacol Toxicol. 2007 Feb;100(2):121-6. PMID: 17244261

Article Published Date : Feb 01, 2007

Study Type : Animal Study

Additional Links

Substances : Ellagic Acid : CK(77) : AC(40)

Diseases : Chemotherapy-Induced Toxicity: Cisplatin : CK(172) : AC(66)

Ellagic acid significantly decreases the damage induced by cyclosporine A (used in organ transplantations).

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Pubmed Data : Basic Clin Pharmacol Toxicol. 2008 Aug;103(2):186-91. PMID: 18816304

Article Published Date : Aug 01, 2008

Study Type : Animal Study

Additional Links

Substances : Ellagic Acid : CK(77) : AC(40)

Diseases : Organ Transplantation : CK(50) : AC(17)

Punica granatum (pomegranate) ameliorates dextran sulfate sodium induced ulcerative colitis.

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Pubmed Data : Phytother Res. 2009 Apr 15. PMID: 19367659

Article Published Date : Apr 15, 2009

Study Type : Animal Study

Additional Links

Substances : Ellagic Acid : CK(77) : AC(40), Pomegranate : CK(146) : AC(61)

Diseases : Colitis: Ulcerative : CK(139) : AC(18), Ulcerative Colitis : CK(429) : AC(39)

Resveratrol works synergistically with ellagic acid, grape seed extract and other phytochemicals to inhibit skin cancer promotion.

Click here to read the entire abstract

Pubmed Data : Cancer Prev Res (Phila). 2010 Feb;3(2):170-8. Epub 2010 Jan 26. PMID: 20103723

Article Published Date : Feb 01, 2010

Study Type : Animal Study

Additional Links

Substances : Ellagic Acid : CK(77) : AC(40), Resveratrol : CK(977) : AC(590), Stilbenes : CK(128) : AC(92)

Diseases : Skin Cancer : CK(417) : AC(171)

Pharmacological Actions : Anticarcinogenic Agents : CK(521) : AC(275), Antiproliferative : CK(1052) : AC(775), Apoptotic : CK(1489) : AC(1114), Chemopreventive : CK(1528) : AC(382)

Additional Keywords : Drug Synergy : CK(327) : AC(147)

Turmeric, garlic, curcumin and ellagic acid protect against aflatoxin-induced mutagenicity and hepatocarcinogenicity.

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Pubmed Data : Cancer Lett. 1997 May 19;115(2):129-33. PMID: 9149115

Article Published Date : May 19, 1997

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482), Ellagic Acid : CK(77) : AC(40), Garlic : CK(485) : AC(160), Turmeric : CK(2995) : AC(1585)

Diseases : Aflatoxicosis : CK(214) : AC(37), Liver Cancer : CK(1641) : AC(266)

Pharmacological Actions : Anticarcinogenic Agents : CK(521) : AC(275), Antimutagenic Agents : CK(75) : AC(44), Hepatoprotective : CK(557) : AC(272)

Various plant phenols inhibit benzo[a]pyrene-induced nuclear a.berrations in mammalian intestinal cells

Click here to read the entire abstract

Pubmed Data : Food Chem Toxicol. 1985 Jan;23(1):47-9. PMID: 4038681

Article Published Date : Jan 01, 1985

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482), Ellagic Acid : CK(77) : AC(40), Quercetin : CK(318) : AC(136)

Diseases : Benzo[a]pyrene-induced Toxicity : CK(62) : AC(33), Gastrointestinal Cancer : CK(43) : AC(11)

Pharmacological Actions : Chemopreventive : CK(1528) : AC(382)

Various plant polyphenols inhibit lung cancer caused by metastatic melanoma.

Click here to read the entire abstract

Pubmed Data : Int Urol Nephrol. 2009 Jul 16. PMID: 7656234

Article Published Date : Jul 16, 2009

Study Type : Animal Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482), EGCG (Epigallocatechin gallate) : CK(859) : AC(109), Ellagic Acid : CK(77) : AC(40), Polyphenols : CK(427) : AC(174), Quercetin : CK(318) : AC(136)

Diseases : Lung Cancer : CK(496) : AC(198), Melanoma : CK(171) : AC(87), Melanoma: Metastatic : CK(21) : AC(13)

Berry components prevent oxidative damage to DNA caused by estradiol (E2) and copper chloride, in vitro.

Click here to read the entire abstract

Pubmed Data : J Am Soc Nephrol. 2002 Sep;13(9):2299-308. PMID: 19003579

Article Published Date : Sep 01, 2002

Study Type : In Vitro Study

Additional Links

Substances : Berries: All : CK(780) : AC(199), Blackberry : CK(17) : AC(13), Ellagic Acid : CK(77) : AC(40)

Diseases : DNA damage : CK(711) : AC(293), Estrogen Dominance : CK(106) : AC(37), Estrogen Dysregulation: 2/4/16 hydroxyestrone ratios : CK(40) : AC(9)

Ellagic acid and curcumin may inhibit cancer through preventing the over-expression of glutathione S-transferases.

Click here to read the entire abstract

Pubmed Data : Food Chem Toxicol. 2007 Feb;45(2):286-95. Epub 2006 Aug 30. PMID: 17046132

Article Published Date : Feb 01, 2007

Study Type : In Vitro Study

Additional Links

Substances : Curcumin : CK(2910) : AC(1482), Ellagic Acid : CK(77) : AC(40)

Diseases : Cancers: Multi-Drug Resistant : CK(92) : AC(73)

Pharmacological Actions : Enzyme Inhibitors : CK(372) : AC(208), Glutathione S-transferase Inhibitor : CK(3) : AC(2)

Ellagic acid demonstrates anticancer activity against bladder cancer cells.

Click here to read the entire abstract

Pubmed Data : Anticancer Res. 2005 Mar-Apr;25(2A):971-9. PMID: 15868936

Article Published Date : Mar 01, 2005

Study Type : In Vitro Study

Additional Links

Substances : Ellagic Acid : CK(77) : AC(40)

Diseases : Bladder Cancer : CK(186) : AC(60)

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