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Fenugreek

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Article Count - 28
Cumulative Knowledge - 81

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Quick Summary: Current access displays 2 out of 25 associated Diseases

Name	Cumulative Knowledge	Article Count	Focus Articles
Diabetes Mellitus: Type 2	13	3	Log in \| Sign up
Insulin Resistance	12	2	Log in \| Sign up

Quick Summary: Current access displays 2 out of 10 associated Pharmacological Actions

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Hepatoprotective	6	3	Log in \| Sign up

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View the Evidence: Substances

A combination of Fenugreek, Fennel and Melissa extracts improves colic in breastfed infants within 1 week.

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Pubmed Data : Phytother Res. 2005 Apr;19(4):335-40. PMID: 16041731

Article Published Date : Apr 01, 2005

Study Type : Human Study

Additional Links

Substances : Fennel : CK(59) : AC(13), Fenugreek : CK(71) : AC(28), Melissa (Lemonbalm) : CK(78) : AC(14)

Diseases : Colic : CK(74) : AC(12)

Fenugreek seeds have a significant therapeutic effect on blood glucose and serum lipid profiles in insulin-dependant type 1 diabetic patients.

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Pubmed Data : Eur J Clin Nutr. 1990 Apr;44(4):301-6. PMID: 2194788

Article Published Date : Apr 01, 1990

Study Type : Human Study

Additional Links

Substances : Fenugreek : CK(71) : AC(28)

Diseases : Diabetes Mellitus: Type 1 : CK(1107) : AC(218)

Fenugreek seeds improves triglyceride levels, glycemic control and decreases insulin resistance in mild type 2 diabetic patients.

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Pubmed Data : J Assoc Physicians India. 2001 Nov;49:1057-61. PMID: 11868855

Article Published Date : Nov 01, 2001

Study Type : Human Study

Additional Links

Substances : Fenugreek : CK(71) : AC(28)

Diseases : Diabetes Mellitus: Type 2 : CK(3429) : AC(341), Insulin Resistance : CK(1034) : AC(221), Triglycerides: Elevated : CK(340) : AC(65)

Maternal galactagogue herbal tea supplementation containing fenugreek seems to be useful for enhancing breast milk production and facilitating infant birth weight regain in early postnatal days.

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Pubmed Data : J Altern Complement Med. 2011 Feb ;17(2):139-42. Epub 2011 Jan 24. PMID: 21261516

Article Published Date : Feb 01, 2011

Study Type : Human Study

Additional Links

Substances : Fenugreek : CK(71) : AC(28)

Diseases : Breast Milk: Inadequate/Poor Quality : CK(60) : AC(7), Lactation Disorders : CK(132) : AC(16)

Therapeutic Actions : Breastfeeding : CK(708) : AC(67)

Pharmacological Actions : Galactogogue : CK(13) : AC(3)

Additional Keywords : Phytotherapy : CK(177) : AC(27), Plant Extracts : CK(3572) : AC(1216)

Dietary fenugreek seed regresses preestablished cholesterol gallstones in mice.

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Pubmed Data : Can J Physiol Pharmacol. 2009 Sep;87(9):684-93. PMID: 19794519

Article Published Date : Sep 01, 2009

Study Type : Animal Study

Additional Links

Substances : Fenugreek : CK(71) : AC(28)

Diseases : Gallstones : CK(160) : AC(30)

Diosgenin, a compound isolated from fenugreek, has chemosensitizing activity against human liver cancer cells.

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Pubmed Data : Cancer Lett. 2010 Jan 4. Epub 2010 Jan 4. PMID: 20053498

Article Published Date : Jan 04, 2010

Study Type : Animal Study

Additional Links

Substances : Diosgenin : CK(2) : AC(1), Fenugreek : CK(71) : AC(28)

Diseases : Liver Cancer : CK(1641) : AC(266)

Pharmacological Actions : Chemosensitizer : CK(197) : AC(159)

Additional Keywords : Drug: Doxorubicin : CK(141) : AC(55), Drug: Paclitaxel : CK(36) : AC(13), Drug-Plant-Vitamin Synergies : CK(1011) : AC(268)

Extracts of jambul, bitter melon (M. charantia), gymnena and fenugreek (T. gracecum) have antidiabetic and drug sparing activities.

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Pubmed Data : Appl Biochem Biotechnol. 2009 Nov 11. Epub 2009 Nov 11. PMID: 19904502

Article Published Date : Nov 11, 2009

Study Type : Animal Study

Additional Links

Substances : Bitter Melon : CK(65) : AC(18), Fenugreek : CK(71) : AC(28), Gymnema Sylvestre : CK(21) : AC(11), Jambul : CK(20) : AC(7)

Diseases : Diabetes Mellitus: Type 2 : CK(3429) : AC(341)

Additional Keywords : Drug: Glimepiride : CK(2) : AC(1), Drug Sparing : CK(451) : AC(49)

Fenugree protects against selenite-induced oxidative stress in experimental cataractogenesis.

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Pubmed Data : Biol Trace Elem Res. 2009 Oct 13. Epub 2009 Oct 13. PMID: 19823776

Article Published Date : Oct 13, 2009

Study Type : Animal Study

Additional Links

Substances : Fenugreek : CK(71) : AC(28)

Diseases : Cataract : CK(182) : AC(55)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

Additional Keywords : Sodium Selenite : CK(39) : AC(18)

Fenugreek (Trigonella foenum graecum) seed polyphenols protects the liver from alcohol toxicity.

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Pubmed Data : Pharmazie. 2007 Apr;62(4):299-304. PMID: 17484288

Article Published Date : Apr 01, 2007

Study Type : Animal Study

Additional Links

Substances : Fenugreek : CK(71) : AC(28), Flavonoids : CK(909) : AC(289), Polyphenols : CK(427) : AC(174)

Diseases : Alcohol Toxicity : CK(212) : AC(85), Alcoholic Liver Disease : CK(146) : AC(50)

Pharmacological Actions : Phase II Detoxification Enzyme Inducer : CK(64) : AC(32)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Fenugreek contains a soluble fiber that improves blood lipid and glucose responses in rats, while also reducing abdominal fat.

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Pubmed Data : J Clin Biochem Nutr. 2008 Nov;43(3):167-74. Epub 2008 Oct 31. PMID:19015751

Article Published Date : Nov 01, 2008

Study Type : Animal Study

Additional Links

Substances : Fenugreek : CK(71) : AC(28)

Diseases : Abdominal Obesity (Midsection Fat) : CK(348) : AC(53)

Fenugreek contains polyphenols which have significant hepatoprotective and liver restorative properties.

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Pubmed Data : Cell Biol Toxicol. 2008 Oct;24(5):391-400. Epub 2008 Feb 1. PMID:18240000

Article Published Date : Oct 01, 2008

Study Type : Animal Study

Additional Links

Substances : Fenugreek : CK(71) : AC(28)

Diseases : Alcoholic Liver Disease : CK(146) : AC(50)

Pharmacological Actions : Hepatoprotective : CK(557) : AC(272)

Additional Keywords : Regenerative Substances : CK(42) : AC(19)

Fenugreek has a protective effecct against alcohol toxicity.

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Pubmed Data : Curr Eye Res. 2006 Feb;31(2):147-53. PMID: 12916070

Article Published Date : Feb 01, 2006

Study Type : Animal Study

Additional Links

Substances : Fenugreek : CK(71) : AC(28), Vitamin C : CK(1274) : AC(238)

Diseases : Alcohol Toxicity : CK(212) : AC(85)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Fenugreek has a protective effect against cypermethrin-induced hepatotoxicity and nephrotoxicity.

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Pubmed Data : Hum Exp Toxicol. 2010 Apr;29(4):311-9. Epub 2010 Feb 10. PMID: 20147568

Article Published Date : Apr 01, 2010

Study Type : Animal Study

Additional Links

Substances : Fenugreek : CK(71) : AC(28)

Diseases : Oxidative Stress : CK(1945) : AC(710), Pyrethroid Insecticide Induced Toxicity : CK(14) : AC(7)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Hepatoprotective : CK(557) : AC(272), Renoprotective : CK(191) : AC(90)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Fenugreek reduces oxidative stress in diabetic rats.

Click here to read the entire abstract

Pubmed Data : J Med Food. 2005 Fall;8(3):382-5. PMID: 16176151

Article Published Date : Sep 01, 2005

Study Type : Animal Study

Additional Links

Substances : Fenugreek : CK(71) : AC(28)

Diseases : Diabetes: Glycation/A1C : CK(186) : AC(33)

Additional Keywords : Natural Substances Versus Drugs : CK(988) : AC(165)

Fenugreek reduces the body weight gain induced by a high-fat diet in obese mice.

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Pubmed Data : Biosci Biotechnol Biochem. 2005 Jun;69(6):1186-8. PMID: 15973051

Article Published Date : Jun 01, 2005

Study Type : Animal Study

Additional Links

Substances : Fenugreek : CK(71) : AC(28)

Diseases : Obesity : CK(1849) : AC(275)

Fenugreek reduces triglyceride accumulation in the liver of rats, indicating its potential therapeutic value in the treatment of fatty liver.

Click here to read the entire abstract

Pubmed Data : Can J Physiol Pharmacol. 2009 Sep;87(9):684-93. PMID: 16477270

Article Published Date : Sep 01, 2009

Study Type : Animal Study

Additional Links

Substances : Fenugreek : CK(71) : AC(28)

Diseases : Fatty Liver : CK(493) : AC(122), Hepatic Steatosis : CK(102) : AC(21), Liver: Fatty : CK(490) : AC(118)

Fenugreek seed polyphenolic extract and quercetin compares favorably to metformin in improving insulin signaling, sensitivity and functioning in a rat model.

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Pubmed Data : Indian J Med Res. 2009 Apr;129(4):401-8. PMID: 19535835

Article Published Date : Apr 01, 2009

Study Type : Animal Study

Additional Links

Substances : Fenugreek : CK(71) : AC(28), Polyphenols : CK(427) : AC(174)

Diseases : Insulin Resistance : CK(1034) : AC(221)

Additional Keywords : Drug: Metformin : CK(195) : AC(23), Natural Substances Versus Drugs : CK(988) : AC(165), Plant Extracts : CK(3572) : AC(1216)

Fenugreek seed polyphenols inhibit ethanol-induced damage in the rat liver.

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Pubmed Data : Cell Biol Toxicol. 2007 Nov;23(6):373-83. Epub 2007 Apr 24. PMID: 17453353

Article Published Date : Nov 01, 2007

Study Type : Animal Study

Additional Links

Substances : Fenugreek : CK(71) : AC(28), Polyphenols : CK(427) : AC(174)

Diseases : Alcoholic Liver Disease : CK(146) : AC(50), Chemically-Induced Liver Damage : CK(475) : AC(175)

Pharmacological Actions : Hepatoprotective : CK(557) : AC(272)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Fenugreek seeds have lipid-lowering and antioxidant effects in high-cholesterol fed rats.

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Pubmed Data : J Agric Food Chem. 2010 Feb 24;58(4):2116-22. PMID: 20108903

Article Published Date : Feb 24, 2010

Study Type : Animal Study

Additional Links

Substances : Fenugreek : CK(71) : AC(28)

Diseases : Hyperlipidemia : CK(1211) : AC(109)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Hypolipidemic : CK(370) : AC(80)

Fenugreek seeds improve swimming endurance in miace through the increase utilization of fatty acids as an energy source.

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Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2006 Aug;52(4):287-92. PMID: 17087056

Article Published Date : Aug 01, 2006

Study Type : Animal Study

Additional Links

Substances : Fenugreek : CK(71) : AC(28)

Diseases : Athletic Performance : CK(479) : AC(61)

Additional Keywords : Enhanced Lipid Utilization : CK(4) : AC(2), Plant Extracts : CK(3572) : AC(1216)

Fenugreek seeds increase rat growth hormone from rat pituitary cells.

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Pubmed Data : J Food Sci. 2007 Jan;72(1):S055-8. PMID: 18816528

Article Published Date : Jan 01, 2007

Study Type : Animal Study

Additional Links

Substances : Fenugreek : CK(71) : AC(28)

Diseases : Human Growth Hormone: Enhancement : CK(74) : AC(10)

Pharmacological Actions : Secretagogue : CK(158) : AC(36)

Additional Keywords : Human Growth Hormone : CK(2) : AC(1)

Pterocarpus marsupium and fenugreek seeds have anti-cataract activity in type 1 diabetic rats.

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Pubmed Data : J Ethnopharmacol. 2004 Aug;93(2-3):289-94. PMID: 15234767

Article Published Date : Aug 01, 2004

Study Type : Animal Study

Additional Links

Substances : Fenugreek : CK(71) : AC(28), Pterocarpus marsupium : CK(26) : AC(9)

Diseases : Cataract : CK(182) : AC(55), Diabetes: Cataract : CK(23) : AC(13)

Pharmacological Actions : Hypoglycemic Agents : CK(563) : AC(156)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Coriandrum sativum and fenugreek has broad antibacterial activity against bacterial diseases of plants.

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Pubmed Data : J Agric Food Chem. 2004 Dec 29;52(26):7862-6. PMID: 15612768

Article Published Date : Dec 29, 2004

Study Type : In Vitro Study

Additional Links

Substances : Coriandrum sativum : CK(53) : AC(27), Fenugreek : CK(71) : AC(28)

Diseases : Bacterial Infections and Mycoses : CK(127) : AC(51)

Pharmacological Actions : Anti-Bacterial Agents : CK(970) : AC(316)

Dill, fenugreek and ajwain (Trachyspermum a.) have antibacterial properties.

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Pubmed Data : BMC Complement Altern Med. 2009;9:30. Epub 2009 Aug 6. PMID: 19656417

Article Published Date : Jan 01, 2009

Study Type : In Vitro Study

Additional Links

Substances : Ajwain : CK(4) : AC(3), Dill : CK(17) : AC(11), Fenugreek : CK(71) : AC(28), Flavonoids : CK(909) : AC(289), Tannic Acid : CK(20) : AC(16)

Pharmacological Actions : Anti-Bacterial Agents : CK(970) : AC(316)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Fenugreek (Trigonella foenum graecum) seed extract prevents ethanol-induced toxicity and cell death in liver cells.

Click here to read the entire abstract

Pubmed Data : Alcohol Alcohol. 2006 May-Jun;41(3):267-73. Epub 2006 Mar 30. PMID: 16574673

Article Published Date : May 01, 2006

Study Type : In Vitro Study

Additional Links

Substances : Fenugreek : CK(71) : AC(28)

Diseases : Alcohol Toxicity : CK(212) : AC(85), Alcoholic Liver Disease : CK(146) : AC(50)

Pharmacological Actions : Anti-Apoptotic : CK(59) : AC(39), Antioxidants : CK(3653) : AC(1318)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

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Herbs from India’s Tribal Pouch: Ginger

Written by Dr Deepak Acharya

Ginger (Zingiber officinale Rosc.) is the member of family Zingiberaceae, locally known as Adrak or Ada in India. This plant is small, rhizomatous, erect and perennial. It is cultivated commercially for edible rhizomes in many parts of India and it has been part of various medicine systems across the world for time immemorial.

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