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Flavonoids
Views 3769
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Focused Research Topics
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246 Diseases Researched for Flavonoids
Name
AC
CK
Focus
Hypertension
14
127
Cardiovascular Diseases
13
95
Endothelial Dysfunction
12
77
Cholesterol: Oxidation
13
61
Oxidative Stress
32
61
Colorectal Cancer
9
51
Inflammation
17
45
HDL: Low
4
40
Radiation Induced Illness
12
38
Arteriosclerosis
6
34
Coronary Artery Disease
4
31
Thrombosis
4
31
Cardiovascular Disease: Prevention
3
30
Hemorrhoids
3
30
Cognitive Decline/Dysfunction
4
24
DNA damage
10
24
Clotting
4
23
Diabetes Mellitus: Type 2
4
23
Aging
8
22
Cholesterol: LDL/HDL ratio
3
22
Esophageal Cancer
3
21
All-Cause Mortality
1
20
Cancer Mortality
1
20
Cardiac Mortality
1
20
Deep Vein Thrombosis
2
20
Diabetes: Cardiovascular Illness
2
20
Glaucoma
1
20
Lipopolysaccharide-Induced Toxicity
8
20
Ocular Hypertension
1
20
Prehypertension
1
20
Smoking
2
20
Breast Cancer
13
18
Colon Cancer
14
18
Aging: Brain
4
16
Cancers: All
15
16
Parkinson's Disease
5
15
Alzheimer's Disease
10
14
Metabolic Syndrome X
3
14
Ovarian Cancer
4
14
Pesticide Toxicity
3
13
Prostate Cancer
10
13
Sunburn
3
13
C-Reactive Protein
2
12
Diabetes Mellitus: Type 2: Prevention
2
12
Heart Failure
2
12
Helicobacter Pylori Infection
3
12
Hyperuricemia
2
12
Myocardial Infarction
2
12
Aging Skin
2
11
Gout
2
11
High Cholesterol
2
11
Skin Diseases: Photo-Aging
2
11
Stroke
2
11
Allergic Rhinitis
1
10
Aphthous Ulcer
1
10
Athletic Performance
1
10
Athletic Performance: Recovery
1
10
Bile Duct Cancer
1
10
Bladder Degeneration
1
10
Blood Platelet Disorders
1
10
Bone Fractures
1
10
Brain Edema
1
10
Chemotherapy
1
10
Chronic Disease
1
10
Chronic Obstructive Pulmonary Disease
1
10
Climacteric
1
10
Common Cold
1
10
Dental Caries
1
10
Dystrophic retinal detachment (DRD)
1
10
Edema
1
10
Erectile Dysfunction
1
10
Eye Diseases: Vitreous Disorders
1
10
Gallbladder Cancer
1
10
Heart Disease: Ischemic
1
10
Hematuria
1
10
Insulin Resistance
1
10
Jet Lag
1
10
Leg Edema
1
10
Libido: Low
1
10
Lung Cancer
8
10
Menopausal Syndrome
1
10
Peripheral vitreochoreoretinal dystrophies (PVCRD)
1
10
Postmenopausal Disorders: Insomnia
1
10
Postoperative Recovery
1
10
Premenstrual syndrome
1
10
Pulmonary Diseases
1
10
Retinal Detachment
1
10
Sexaul Dysfunction
1
10
Thromboembolism
1
10
Tinnitus
1
10
Vericose Veins: Bladder
1
10
Wrinkles
1
10
Neurodegenerative Diseases
7
9
Pancreatic Cancer
5
9
Cancers: Drug Resistant
7
8
Lipid Peroxidation
5
8
Chemically-Induced Liver Damage
4
7
Colorectal Cancer: Prevention
2
7
Gastric Ulcer
4
7
Hyperlipidemia
4
7
Liver Cancer: Prevention
2
7
Obesity
4
7
Breast Cancer: Metastatic
3
6
Diabetes Mellitus: Type 1
4
6
Brain Inflammation
4
5
Cervical Cancer
5
5
Liver Cancer
4
5
Tumors
4
5
Aging: Immunosenecence
2
4
Alcohol Toxicity
2
4
Alcoholic Liver Disease
2
4
Breast Cancer: Triple Negative
2
4
Cancer Metastasis
2
4
Cancers: Multi-Drug Resistant
4
4
Cerebral Ischemia
2
4
HIV Infections
4
4
Hypercholesterolemia
2
4
Hyperglycemia
3
4
Immune Disorders: Low Immune Function
2
4
Inflammatory Bowel Diseases
2
4
Memory Disorders
2
4
Oral Cancer
2
4
Seizures
2
4
Advanced Glycation End products (AGE)
2
3
Allergies
2
3
Atherosclerosis
2
3
Chemotherapy-Induced Toxicity: Cisplatin
2
3
Cholera
2
3
Dementia
3
3
Depression
2
3
Diabetes: Cataract
2
3
Dioxin Toxicity
2
3
MRSA
2
3
Melanoma
3
3
Rheumatoid Arthritis
2
3
Snake Bite: Venom Toxicity
2
3
Abdominal Obesity (Midsection Fat)
1
2
Aluminum Toxicity
1
2
Anaphylaxis
1
2
Arsenic Poisoning
1
2
Arthritis
1
2
Aspirin-Induced Toxicity
1
2
Autism
1
2
Bladder Cancer
2
2
Brain Injury: Hippocampal Damage
1
2
Brain: Microglial Activation
2
2
Breast Cancer: Lung Metastasis
1
2
Cataract
1
2
Cerebral Vasospasm
1
2
Chikungunya Virus
2
2
Colon Polyps
1
2
Convulsions
1
2
Cystic Fibrosis
2
2
Diabetes: Cognitive Dysfunction
1
2
Diabetic Nephropathy
1
2
Diesel Exhaust Particle Toxicity
1
2
Dopamine Deficiency
1
2
Dyslipidemias
1
2
Estrogen Dominance
2
2
Fatty Liver
1
2
Food Allergies
1
2
Fructose-Induced Toxicity
1
2
Giardiasis
2
2
Heat Stroke
1
2
Hypothyroidism
1
2
Hypoxia
1
2
IgA Deficiency
1
2
IgE-Mediated Hypersensitivity
1
2
Infertility: Aging Associated
1
2
Infertility: Female
1
2
Infertility: Male
1
2
Intestinal Diseases
1
2
Intestinal Permeability
2
2
Irritable Bowel Syndrome
1
2
Leaky Gut Syndrome
2
2
Learning disorders
1
2
Leukemia: Acute myelogenous leukemia (AML)
1
2
Leukemia: Chronic myelogenous leukemia (CML)
1
2
Low Immune Function: Thymus Dysfunction
1
2
Lymphoma
1
2
Mouse Endogenous Retroviruses
1
2
NSAID-induced toxicity
1
2
Neuroblastoma
1
2
Osteoarthritis
1
2
Osteoporosis
1
2
Ovariectomy Associated Adverse Changes
1
2
Periodontitis
1
2
Pesticide-Induced Toxicity: Organophosphates
1
2
Petroleum Exposure And Toxicity
1
2
Prenatal Nutrition: Health of the Offspring
1
2
Promyelocytic leukemia
2
2
Prostatic Hyperplasia: Benign
1
2
Radiation Induced Illness: Bone Marrow
1
2
Scars
1
2
Skin Cancer: Prevention
1
2
Sperm Quality: Low
1
2
Thyroid Cancer
2
2
Ultraviolet Radiation Induced Damage
2
2
Wound Healing
1
2
Acute lymphoblastic leukemia (ALL)
1
1
Allergic Airway Diseases
1
1
Amyotrophic Lateral Sclerosis
1
1
Anemia: Hemolytic
1
1
Brain Injury: Traumatic
1
1
Brain Ischemia
1
1
Candida Infection
1
1
Chronic Myeloid Leukemia
1
1
Clostridium Infections
1
1
Copper Toxicity
1
1
Cryptosporidiosis
1
1
Cytomegalovirus Infections
1
1
Epstein-Barr Virus Infections
1
1
Excitotoxicity
1
1
Glioblastoma
1
1
Glioma
1
1
Glucosephosphate Dehydrogenase Deficiency
1
1
HSV-1
1
1
HSV-2
1
1
High Homocysteine
1
1
Hyperinsulinism
1
1
Hypertension: Pulmonary
1
1
Influenza in Swine
1
1
Kidney Damage: Drug-Induced
1
1
Leishmaniasis
1
1
Leukemia
1
1
Liver Disease
1
1
Malaria
1
1
Malignant Melanoma
1
1
Neurological Conditions
1
1
Non-Small-Cell Lung Carcinoma
1
1
Nonalcoholic fatty liver disease (NAFLD)
1
1
Osteosarcoma
1
1
Protozoan Infections
1
1
Psychiatric Disorders
1
1
Radiation-Induced Illness: Cesium-137 Exposure
1
1
Rhinovirus Infection
1
1
Schizophrenia
1
1
Simian virus 40 (SV40)
1
1
Staphylococcus aureus infection
1
1
Sugar (Sucrose) Toxicity
1
1
Swine Flu Associated Virus
1
1
Tertiary butyl hydroperoxide toxicity
1
1
Testicular Cancer
1
1
Triglycerides: Elevated
1
1
Vibrio Infections
1
1
Weight Problems
1
1
109 Pharmacological Actions Researched for Flavonoids
Name
AC
CK
Focus
Antioxidants
102
232
Apoptotic
54
67
Chemopreventive
23
64
Platelet Aggregation Inhibitors
7
62
Antiproliferative
46
61
Anti-Inflammatory Agents
25
54
Neuroprotective Agents
22
41
Hypotensive
2
40
Cell cycle arrest
23
35
NF-kappaB Inhibitor
13
32
Antineoplastic Agents
18
30
Tumor Necrosis Factor (TNF) Alpha Inhibitor
12
29
Radioprotective
11
28
Cyclooxygenase 2 Inhibitors
13
27
Hypoglycemic Agents
7
27
Anticarcinogenic Agents
18
26
Cardioprotective
5
26
Antihypertensive Agents
4
23
Vasodilator Agents
4
23
Analgesics
2
20
Enzyme Inhibitors
15
19
Anti-metastatic
9
16
Anticholesteremic Agents
4
15
Hepatoprotective
8
14
Anti-Allergic Agents
2
12
MicroRNA modulator
2
12
Anti-Platelet
2
11
Interleukin-6 Downregulation
7
11
Nitric Oxide Enhancer
2
11
Anti Inflammatory
2
10
Anti-thrombotic
1
10
Calcium Channel Blockers
1
10
Cardiovascular Agents
1
10
Anti-Ulcer Agents
4
8
Chemosensitizer
7
8
Immunomodulatory
4
8
Tumor Suppressor Protein p53 Upregulation
7
8
Anti-Apoptotic
4
7
Antiviral Agents
7
7
Matrix metalloproteinase-2 (MMP-2) inhibitor
4
7
Anti-Bacterial Agents
5
6
Chemotherapeutic
5
6
Interleukin-1 beta downregulation
4
6
Anti-Angiogenic
4
5
Glycogen synthase kinase-3beta (GSK-3beta) Inhibitor
1
5
Anticonvulsants
2
4
Phase II Detoxification Enzyme Inducer
2
4
Alpha-glucosidase inhibitor
2
3
Anti-HIV Agents
3
3
Cytoprotective
2
3
Genoprotective
2
3
Interleukin-10 downregulation
2
3
Nitric Oxide Inhibitor
2
3
Renoprotective
2
3
Aldose reductase inhibitor
1
2
Anti-Tumor
1
2
Antidepressive Agents
1
2
Antidiarrheals
1
2
Antimicrobial
1
2
Antimutagenic Agents
2
2
Caspase-3 Activation
2
2
Chemoprotective Agents
1
2
Cyclooxygenase Inhibitors
1
2
Dopaminergic
1
2
Matrix metalloproteinase-9 (MMP-9) inhibitor
1
2
Proteasome Inhibitors
2
2
Vascular Cell Adhesion Molecule-1 Inhibitor
2
2
Vascular Endothelial Growth Factor A Inhibitor
1
2
5-lipoxygenase Inhibitor
1
1
Anti-Estrogenic
1
1
Antifungal Agents
1
1
Antiprotozoal Agents
1
1
Aromatase Inhibitors
1
1
Cyclooxygenase 1 Inhibitor
1
1
Cytotoxic
1
1
Cytotoxicity
1
1
DNA Repair Up-regulation
1
1
E-cadherin down-regulation
1
1
Estrogen Receptor Agonist
1
1
Expectorants
1
1
Forkhead Transcription Factor Family O (FOXO) Modulator
1
1
Gastrointestinal Agents
1
1
Gastroprotective
1
1
Glucagon Like Peptide 1 (GLP-1) Down-Regulation
1
1
Glucagon Like peptide 1 (GLP-1) Up-regulation
1
1
Gluconeogenesis Inhibitor
1
1
Glutathione Upregulation
1
1
Histamine Antagonists
1
1
Histone deacetylase inhibitor
1
1
Hypolipidemic
1
1
Hypoxia-inducible factor-1 (HIF-1) inhibitor
1
1
Insulin-releasing
1
1
Leishmanicidal
1
1
Leukotriene Antagonists
1
1
Matrix metalloproteinase-1 (MMP-1) inhibitor
1
1
Metal Chelation: Copper
1
1
Neurominidase Inhibitor
1
1
Nrf2 activation
1
1
P-glycoprotein Inhibitors
1
1
P21 Activation
1
1
P38 Mitogen-Activated Protein Kinase Modulator
1
1
Photoprotective
1
1
Postaglandin PGE2 downregulation
1
1
Prostaglandin PGE2 downregulation
1
1
Radiosensitizer
1
1
Telomere Protective
1
1
Topoisomerase II Inhibitor
1
1
Vasoprotective
1
1
Xanthine oxidase inhibitor
1
1
Research Articles
379
Cumulative Knowledge Score
613
Overall Research Rating
EXCELLENT
View the Evidence:
504 Abstracts with Flavonoids Research
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[+]
"Dietary flavonoid for preventing colorectal neoplasms."
Dec 31, 2011
Click here to read the entire abstract
Pubmed Data
: Cochrane Database Syst Rev. 2012 ;8:CD009350. Epub 2012 Aug 15. PMID:
22895989
Article Published Date
: Dec 31, 2011
Study Type
: Meta Analysis
Additional Links
Substances
:
Flavonoids
Diseases
:
Colorectal Cancer
[+]
Cocoa products have blood-pressure lowering capacity.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: Am J Hypertens. 2010 Jan;23(1):97-103. Epub 2009 Nov 12. PMID:
19910929
Article Published Date
: Jan 01, 2010
Study Type
: Meta Analysis
Additional Links
Substances
:
Flavonoids
Diseases
:
Hypertension
Pharmacological Actions
:
Hypotensive
[+]
Dark chocolate is superior to placebo in reducing systolic hypertension or diastolic prehypertension.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: BMC Med. 2010;8:39. Epub 2010 Jun 28. PMID:
20584271
Article Published Date
: Jan 01, 2010
Study Type
: Meta Analysis
Additional Links
Substances
:
Flavonoids
Diseases
:
Hypertension
,
Prehypertension
Pharmacological Actions
:
Hypotensive
[+]
Flavonoid intake reduces all-cause mortality.
Mar 31, 2015
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2015 Apr 1. Epub 2015 Apr 1. PMID:
25832340
Article Published Date
: Mar 31, 2015
Study Type
: Meta Analysis
Additional Links
Substances
:
Flavonoids
Diseases
:
All-Cause Mortality
,
Cancer Mortality
,
Cardiac Mortality
[+]
Flavonoids have a promising role in improving visual function in patients with glaucoma and ocular hypertension.
Sep 03, 2015
Click here to read the entire abstract
Pubmed Data
: Graefes Arch Clin Exp Ophthalmol. 2015 Sep 4. Epub 2015 Sep 4. PMID:
26340868
Article Published Date
: Sep 03, 2015
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Cocoa
,
Flavonoids
,
Green Tea
,
Red Wine Extract
Diseases
:
Glaucoma
,
Ocular Hypertension
[+]
High intake of flavonols may reduce the risk of colon cancer and high intake of flavones may reduce the risk of rectal cancer.
Jul 22, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2018 Jul 23 ;10(7). Epub 2018 Jul 23. PMID:
30041489
Article Published Date
: Jul 22, 2018
Study Type
: Meta Analysis
Additional Links
Substances
:
Apigenin
,
Flavonoids
,
Quercetin
Diseases
:
Colorectal Cancer
,
Rectal Cancer
Pharmacological Actions
:
Chemopreventive
[+]
Higher intakes of total flavonoids and subclasses are associated with lower risk of T2DM.
Apr 30, 2018
Click here to read the entire abstract
Pubmed Data
: Medicine (Baltimore). 2018 May ;97(19):e0686. PMID:
29742713
Article Published Date
: Apr 30, 2018
Study Type
: Meta Analysis
Additional Links
Substances
:
Flavan-3-ols
,
Flavonoids
,
Isoflavones
Diseases
:
Diabetes Mellitus: Type 2: Prevention
Additional Keywords
:
Risk Reduction
[+]
High polyphenol chocolate is effective in improving the atherosclerotic cholesterol profile in patients with diabetes by increasing HDL cholesterol and improving the cholesterol:HDL ratio.
Nov 01, 2010
Click here to read the entire abstract
Pubmed Data
: Diabet Med. 2010 Nov;27(11):1318-21. PMID:
20968113
Article Published Date
: Nov 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Cholesterol: LDL/HDL ratio
,
Diabetes: Cardiovascular Illness
,
HDL: Low
[+]
"Kidney function in metabolic syndrome may be improved with Pycnogenol®."
May 31, 2010
Click here to read the entire abstract
Pubmed Data
: Panminerva Med. 2010 Jun ;52(2 Suppl 1):27-32. PMID:
20657531
Article Published Date
: May 31, 2010
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Metabolic Syndrome X
Pharmacological Actions
:
Antihypertensive Agents
[+]
A Chinese green tea polyphenol extract has evident anti-plaque effect.
Sep 01, 2000
Click here to read the entire abstract
Pubmed Data
: Zhonghua Kou Qiang Yi Xue Za Zhi. 2000 Sep;35(5):383-4. PMID:
11780252
Article Published Date
: Sep 01, 2000
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Green Tea
,
Polyphenols
Diseases
:
Dental Caries
[+]
A combination of apigenin and EGCG prevent colorectal cancer recurrence.
Apr 14, 2008
Click here to read the entire abstract
Pubmed Data
: World J Gastroenterol. 2008 Apr 14;14(14):2187-93. PMID:
18407592
Article Published Date
: Apr 14, 2008
Study Type
: Human Study
Additional Links
Substances
:
Apigenin
,
Catechin
,
Flavonoids
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Risk Reduction
[+]
A combination of diosmin and hesperidin significantly reduces bleeding in patients with acute internal hemorrhoids.
Jun 01, 2005
Click here to read the entire abstract
Pubmed Data
: Clin Ther. 2005 Jun;27(6):746-54. PMID:
16117981
Article Published Date
: Jun 01, 2005
Study Type
: Human Study
Additional Links
Substances
:
Diosmin
,
Flavonoids
,
Hesperidin
Diseases
:
Hemorrhoids
[+]
A combination of pine bark extract and nattokinase prevents venous thrombosis in long-haul flights.
Sep 01, 2003
Click here to read the entire abstract
Pubmed Data
: Angiology. 2003 Sep-Oct;54(5):531-9. PMID:
14565628
Article Published Date
: Sep 01, 2003
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Nattokinase
Diseases
:
Deep Vein Thrombosis
,
Thromboembolism
,
Thrombosis
Pharmacological Actions
:
Platelet Aggregation Inhibitors
[+]
A flavonoid supplement improves leg health and reduces fluid retention in premenopausal women.
Jan 01, 2004
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2004 Jan;11(1):11-7. PMID:
14971717
Article Published Date
: Jan 01, 2004
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Premenstrual syndrome
Additional Keywords
:
Oligomeric Procyanidins
,
Water Retention
[+]
A flavonol-rich diet may decrease the risk of advanced adenoma recurrence.
May 31, 2008
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Epidemiol Biomarkers Prev. 2008 Jun ;17(6):1344-53. PMID:
18559549
Article Published Date
: May 31, 2008
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Chemopreventive
[+]
A polyphenol-rich beverage reduces symptoms associated with the common cold.
Oct 01, 2010
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2010 Oct;104(8):1156-64. Epub 2010 May 21. PMID:
20487584
Article Published Date
: Oct 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Common Cold
[+]
Acute consumption of flavanol-rich cocoa and the reversal of endothelial dysunfction in smokers.
Oct 04, 2005
Click here to read the entire abstract
Pubmed Data
: J Am Coll Cardiol. 2005 Oct 4;46(7):1276-83. PMID:
16198843
Article Published Date
: Oct 04, 2005
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Endothelial Dysfunction
,
Smoking
[+]
Apple peel extract inhibits the growth of Helicobacter pylori, and attenuates damage to the gastric mucosa caused by neutrophils.
Sep 09, 2009
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2009 Sep 9;57(17):7743-9. PMID:
19691323
Article Published Date
: Sep 09, 2009
Study Type
: Human Study
Additional Links
Substances
:
Apples
,
Flavonoids
,
Polyphenols
Diseases
:
Helicobacter Pylori Infection
Additional Keywords
:
Plant Extracts
,
Proanthocyanidins
[+]
Auricular acupressure at some specific acupoints can significantly improve the absorption of naringenin and hesperetin in the extracts form C. aurantium L.
Apr 30, 2008
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Altern Complement Med. 2008 May ;14(4):423-5. PMID:
18576924
Article Published Date
: Apr 30, 2008
Study Type
: Human Study
Additional Links
Substances
:
Bitter Orange
,
Flavonoids
,
Naringenin
Therapeutic Actions
:
Acupressure: Auricular
Additional Keywords
:
Absorption
[+]
Bilberry has anti-inflammatory properties.
Sep 01, 2010
Click here to read the entire abstract
Pubmed Data
: Eur J Nutr. 2010 Sep;49(6):345-55. Epub 2010 Feb 2. PMID:
20119859
Article Published Date
: Sep 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Bilberry
,
Flavonoids
,
Polyphenols
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
NF-kappaB Inhibitor
[+]
Blood pressure is reduced and insulin sensitivity increased in glucose-intolerant, hypertensive subjects after 15 days of consuming high-polyphenol dark chocolate.
Sep 01, 2008
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2008 Sep;138(9):1671-6. PMID:
18716168
Article Published Date
: Sep 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Cardiovascular Diseases
,
Hypertension
,
Insulin Resistance
[+]
Blueberry flavonoid consumption promotes a positive mood and are a possible way to prevent dysphoria and depression.
Feb 19, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2017 Feb 20 ;9(2). Epub 2017 Feb 20. PMID:
28230732
Article Published Date
: Feb 19, 2017
Study Type
: Human Study
Additional Links
Substances
:
Blueberry
,
Flavonoids
Diseases
:
Depression
Pharmacological Actions
:
Antidepressive Agents
[+]
Cocoa inhibits LDL oxidation both in vitro and ex vivo.
Apr 06, 1999
Click here to read the entire abstract
Pubmed Data
: Mutat Res. 1999 Apr 6;440(2):181-8. PMID:
11185658
Article Published Date
: Apr 06, 1999
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Arteriosclerosis
,
Cholesterol: Oxidation
Pharmacological Actions
:
Antioxidants
[+]
Cocoa powder and dark chocolate may favorably affect cardiovascular disease risk status by modestly reducing LDL oxidation susceptibility and increasing serum total antioxidant capacity and HDL-cholesterol concentrations.
Nov 01, 2001
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2001 Nov;74(5):596-602. PMID:
11684527
Article Published Date
: Nov 01, 2001
Study Type
: Human Study
Additional Links
Substances
:
Catechin
,
Flavonoids
Diseases
:
Cardiovascular Diseases
,
Cholesterol: Oxidation
,
HDL: Low
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Proanthocyanidins
[+]
Coffee appears to have a beneficial effect on pulmonary function, among non-smokers.
Oct 15, 2010
Click here to read the entire abstract
Pubmed Data
: Int J Cancer. 2010 Oct 15;127(8):1758-68. PMID:
19372215
Article Published Date
: Oct 15, 2010
Study Type
: Human Study
Additional Links
Substances
:
Coffee
,
Flavonoids
,
Polyphenols
Diseases
:
Pulmonary Diseases
,
Smoking
[+]
Consumption of flavanone-rich citrus juice in quantities commonly consumed can acutely enhance blood flow to the brain in healthy young adults.
Nov 30, 2016
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2016 Dec ;116(12):2160-2168. Epub 2017 Jan 16. PMID:
28091350
Article Published Date
: Nov 30, 2016
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Vitamin C
[+]
Consumption of high flavanol dark chocolate confers modest improvements in cardiovascular function.
Jul 31, 2015
Click here to read the entire abstract
Pubmed Data
: Vascul Pharmacol. 2015 Aug ;71:70-8. Epub 2015 Apr 11. PMID:
25869509
Article Published Date
: Jul 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Chocolate
,
Cocoa
,
Flavonoids
Diseases
:
Cardiovascular Disease: Prevention
,
Cardiovascular Diseases
Pharmacological Actions
:
Cardiovascular Agents
[+]
Consumption of phytochemical-rich foods may prevent the development of hypertension.
Feb 28, 2015
Click here to read the entire abstract
Pubmed Data
: Eur J Clin Nutr. 2015 Mar ;69(3):392-8. Epub 2014 Nov 12. PMID:
25387902
Article Published Date
: Feb 28, 2015
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Hypertension
Additional Keywords
:
Dietary Modification
,
Plant Extracts
,
Risk Reduction
[+]
Continuous intake of polyphenolic compounds containing cocoa powder reduces LDL oxidative susceptibility and has beneficial effects on plasma HDL-cholesterol concentrations in humans.
Jun 02, 2009
Click here to read the entire abstract
Pubmed Data
: Proc Natl Acad Sci U S A. 2009 Jun 2;106(22):9033-8. Epub 2009 May 18. PMID:
17344491
Article Published Date
: Jun 02, 2009
Study Type
: Human Study
Additional Links
Substances
:
Catechin
,
Flavonoids
,
Polyphenols
Diseases
:
Cholesterol: Oxidation
,
HDL: Low
Pharmacological Actions
:
Antioxidants
[+]
Dark chocolate consumption increases HDL cholesterol concentration and chocolate fatty acids may inhibit lipid peroxidation in healthy humans.
Dec 01, 2008
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol.2008 Dec;46(12):3586-92. Epub 2008 Sep 3 PMID:
15454274
Article Published Date
: Dec 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Chocolate
,
Flavonoids
,
Polyphenols
Diseases
:
Cholesterol: LDL/HDL ratio
,
Cholesterol: Oxidation
,
HDL: Low
[+]
Dark chocolate improves coronary vasomotion and reduces platelet reactivity.
Nov 20, 2007
Click here to read the entire abstract
Pubmed Data
: Circulation. 2007 Nov 20;116(21):2376-82. Epub 2007 Nov 5. PMID:
17984375
Article Published Date
: Nov 20, 2007
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Blood Platelet Disorders
,
Clotting
,
Coronary Artery Disease
,
Endothelial Dysfunction
Pharmacological Actions
:
Anti-Platelet
,
Vasodilator Agents
[+]
Dietary flavonoids improve urinary arsenic elimination among Mexican women.
Jun 30, 2018
Click here to read the entire abstract
Pubmed Data
: Nutr Res. 2018 Jul ;55:65-71. Epub 2018 Apr 21. PMID:
29914629
Article Published Date
: Jun 30, 2018
Study Type
: Human Study
Additional Links
Substances
:
Apigenin
,
Flavan-3-ols
,
Flavonoids
Diseases
:
Arsenic Poisoning
Pharmacological Actions
:
Detoxifier
Problem Substances
:
Arsenic
[+]
Flavanone intake is inversely associated with esophageal cancer risk and may account, with vitamin C, for the protective effect of fruit, especially citrus fruit, on esophageal cancer.
Apr 10, 2000
Click here to read the entire abstract
Pubmed Data
: Arch Intern Med. 2000 Apr 10;160(7):1009-13. PMID:
17192901
Article Published Date
: Apr 10, 2000
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Fruit: All
,
Grapefruit
,
Lemon Juice
,
Orange
,
Vitamin C
Diseases
:
Esophageal Cancer
Additional Keywords
:
Risk Reduction
[+]
Flavonoid antioxidants may have therapeutic value in PVCRD and DRD for the purpose of improving and stabilizing the visual functions and for neuroprotection.
Aug 01, 2009
Click here to read the entire abstract
Pubmed Data
: Inflamm Res. 2009 Aug;58(8):513-21. Epub 2009 Mar 11. PMID:
15384840
Article Published Date
: Aug 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Ginkgo biloba
Diseases
:
Dystrophic retinal detachment (DRD)
,
Eye Diseases: Vitreous Disorders
,
Peripheral vitreochoreoretinal dystrophies (PVCRD)
,
Retinal Detachment
Pharmacological Actions
:
Antioxidants
[+]
Flavonoid consumption may be beneficial for disease prevention.
May 14, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutr Diabetes. 2017 May 15 ;7(5):e276. Epub 2017 May 15. PMID:
28504712
Article Published Date
: May 14, 2017
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
C-Reactive Protein
,
Chronic Disease
,
Inflammation
,
Obesity
Additional Keywords
:
Anti-Obesity Agents
[+]
Flavonoid consumption reduces the risk of esophageal cancer.
Jun 01, 2007
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2007 Jun;21(6):501-6. PMID:
19444905
Article Published Date
: Jun 01, 2007
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Flavonoids
Diseases
:
Esophageal Cancer
Additional Keywords
:
Proanthocyanidins
,
Risk Reduction
[+]
Flavonoid-rich dark chocolate improves endothelial function and increases plasma antioxidant concentrations in healthy adults.
Jun 01, 2004
Click here to read the entire abstract
Pubmed Data
: J Am Coll Nutr. 2004 Jun;23(3):197-204. PMID:
15190043
Article Published Date
: Jun 01, 2004
Study Type
: Human Study
Additional Links
Substances
:
Cocoa
,
Flavonoids
Diseases
:
Endothelial Dysfunction
[+]
Flavonoid-rich dark chocolate intake significantly improved coronary circulation in healthy adults.
Jan 24, 2009
Click here to read the entire abstract
Pubmed Data
: Int J Cardiol. 2009 Jan 24;131(3):424-9. Epub 2007 Nov 28. PMID:
18045712
Article Published Date
: Jan 24, 2009
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Coronary Artery Disease
[+]
Flavonoids (hesperidin) have therapeutic value in the treatment of bleeding bladder varices.
Oct 01, 2003
Click here to read the entire abstract
Pubmed Data
: Actas Urol Esp. 2003 Oct;27(9):732-4. PMID:
14626685
Article Published Date
: Oct 01, 2003
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Hesperidin
Diseases
:
Bladder Degeneration
,
Hematuria
,
Vericose Veins: Bladder
[+]
Flavonoids from vegetables and fruits may be linked with the reduced risk of colorectal cancer.
Sep 30, 2016
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2016 Oct ;116(7):1275-1287. Epub 2016 Sep 21. PMID:
27650133
Article Published Date
: Sep 30, 2016
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Fruit: All
,
Vegetables: All
Diseases
:
Colorectal Cancer
,
Colorectal Cancer: Prevention
Additional Keywords
:
COLORECTAL CANCER
,
Colorectal Cancer: Prevention
,
Flavonoids
,
Fruit: All
,
Risk Reduction
,
Vegetables: All
[+]
Hesperidin has therapeutic value in the treatment of recurrent aphthous stomatitis.
Apr 01, 2006
Click here to read the entire abstract
Pubmed Data
: Georgian Med News. 2006 Apr(133):31-3. PMID:
16705221
Article Published Date
: Apr 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Hesperidin
Diseases
:
Aphthous Ulcer
[+]
Higher consumption of red wine, tea, peppers, blueberries and strawberries, was associated with reduced risk of total and cause-specific mortality.
Jun 12, 2017
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2017 Jun 13:1-8. Epub 2017 Jun 13. PMID:
28606222
Article Published Date
: Jun 12, 2017
Study Type
: Human Study
Additional Links
Substances
:
Blueberry
,
Flavonoids
,
Red Wine Extract
,
Strawberry
Diseases
:
All-Cause Mortality
Additional Keywords
:
Risk Reduction
[+]
Higher dietary intake of flavonoid may be inversely associated with depressive symptoms.
Apr 23, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2018 Apr 24 ;23(5). Epub 2018 Apr 24. PMID:
29695122
Article Published Date
: Apr 23, 2018
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Depression
Additional Keywords
:
depression
,
Flavonoids
,
Risk Reduction
[+]
Higher intake of black tea and particular classes of flavonoids were associated with lower risk of fracture related hospitalizations in elderly women at high risk of fracture.
Aug 11, 2015
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2015 Aug 12. Epub 2015 Aug 12. PMID:
26269364
Article Published Date
: Aug 11, 2015
Study Type
: Human Study
Additional Links
Substances
:
Black Tea
,
Flavonoids
Diseases
:
Bone Fractures
Additional Keywords
:
Risk Reduction
[+]
Higher intake of flavonoids, particularly from berries, appears to reduce rates of cognitive decline in older adults.
Jun 30, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Ann Neurol. 2012 Jul ;72(1):135-43. Epub 2012 Apr 26. PMID:
22535616
Article Published Date
: Jun 30, 2012
Study Type
: Human Study
Additional Links
Substances
:
Berries: All
,
Blueberry
,
Flavonoids
,
Strawberry
Diseases
:
Aging
,
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Risk Reduction
[+]
Higher intakes of anthocyanins and flavonols and their anti-inflammatory effects may be a key component underlying the reduction in risk of certain chronic diseases.
May 26, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Am J Clin Nutr. 2015 May 27. Epub 2015 May 27. PMID:
26016863
Article Published Date
: May 26, 2015
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Flavonoids
,
Fruit: All
,
Vegetables: All
Diseases
:
Chronic Disease
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Risk Reduction
[+]
Higher intakes of flavonols and flavanones as well as black tea consumption may be associated with lower risk of ovarian cancer.
Oct 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Am J Clin Nutr. 2014 Nov ;100(5):1344-51. Epub 2014 Aug 20. PMID:
25332332
Article Published Date
: Oct 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Black Tea
,
Flavonoids
Diseases
:
Ovarian Cancer
Additional Keywords
:
Risk Reduction
[+]
Higher intakes of fruit-based flavonoids were associated with a lower risk of nonfatal MI and ischemic stroke in men.
Aug 02, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Am J Clin Nutr. 2016 Aug 3. Epub 2016 Aug 3. PMID:
27488237
Article Published Date
: Aug 02, 2016
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Flavonoids
,
Fruit: All
Diseases
:
Cardiovascular Diseases
,
Myocardial Infarction
,
Stroke
Additional Keywords
:
Risk Reduction
[+]
Individuals using the Army Physical Fitness Test while supplementing with Pycnogenol had a lower increase in oxidative stress with a faster recovery to almost normal levels.
Nov 30, 2013
Click here to read the entire abstract
Pubmed Data
: J Sports Med Phys Fitness. 2013 Dec ;53(6):644-54. PMID:
24247188
Article Published Date
: Nov 30, 2013
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Pycnogenol (Pine Bark)
Diseases
:
Athletic Performance
,
Athletic Performance: Recovery
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Supplementation
[+]
Intake of flavonoid-rich wine, tea, and chocolate by elderly men and women is associated with better cognitive test performance.
Jan 01, 2009
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2009 Jan;139(1):120-7. Epub 2008 Dec 3. PMID:
19056649
Article Published Date
: Jan 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Black Tea
,
Flavonoids
,
Green Tea
,
Wine
Diseases
:
Aging: Brain
,
Cognitive Decline/Dysfunction
[+]
Intake of total polyphenols and some classes of polyphenols is inversely associated with diabetes in elderly People at high cardiovascular disease risk.
Mar 08, 2016
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2016 Mar 9. Epub 2016 Mar 9. PMID:
26962181
Article Published Date
: Mar 08, 2016
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Cardiovascular Disease: Prevention
,
Diabetes Mellitus: Type 2: Prevention
Additional Keywords
:
Risk Reduction
[+]
L-arginine in combination with Pycnogenol causes a significant improvement in sexual function in men with erectile dysfunction without any side effects.
May 01, 2003
Click here to read the entire abstract
Pubmed Data
: J Sex Marital Ther. 2003 May-Jun;29(3):207-13. PMID:
12851125
Article Published Date
: May 01, 2003
Study Type
: Human Study
Additional Links
Substances
:
Arginine
,
Flavonoids
Diseases
:
Erectile Dysfunction
Pharmacological Actions
:
Nitric Oxide Enhancer
,
Platelet Aggregation Inhibitors
[+]
Moderate consumption of chocolate might be associated with a lower risk of heart failure in male physicians.
Nov 30, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Eur J Heart Fail. 2014 Dec ;16(12):1372-6. Epub 2014 Oct 14. PMID:
25311633
Article Published Date
: Nov 30, 2014
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Heart Failure
Pharmacological Actions
:
Cardioprotective
[+]
Modulation of aflatoxin biomarkers in human blood and urine by green tea polyphenols intervention.
Jan 31, 2008
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Carcinogenesis. 2008 Feb ;29(2):411-7. Epub 2008 Jan 12. PMID:
18192689
Article Published Date
: Jan 31, 2008
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
,
Tea
Diseases
:
Aflatoxicosis
,
Liver Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
Problem Substances
:
Aflatoxin
[+]
One week of dark chocolate ingestion improved lipid profiles and decreased platelet reactivity within the total group while reducing inflammation only in women.
Jul 01, 1999
Click here to read the entire abstract
Pubmed Data
: Neurotoxicol Teratol. 1999 Jul-Aug;21(4):349-57. PMID:
19005437
Article Published Date
: Jul 01, 1999
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
C-Reactive Protein
,
Clotting
,
Thrombosis
[+]
People who preferentially consume high amounts of quercetin-containing foods have a reduced risk of thrombosis and potential CVD risk.
Aug 31, 2006
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2006 Sep ;96(3):482-8. PMID:
16925853
Article Published Date
: Aug 31, 2006
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Onion
,
Quercetin
,
Soup
Diseases
:
Cardiovascular Disease: Prevention
,
Cardiovascular Diseases
,
Thrombosis
Pharmacological Actions
:
Anti-thrombotic
,
Cardioprotective
[+]
Prevention of edema in long flights with Pycnogenol.
Jun 30, 2005
Click here to read the entire abstract
Pubmed Data
: Clin Appl Thromb Hemost. 2005 Jul ;11(3):289-94. PMID:
16015414
Article Published Date
: Jun 30, 2005
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Leg Edema
Pharmacological Actions
:
Platelet Aggregation Inhibitors
[+]
Prevention of recurrent venous thrombosis and post-thrombotic syndrome.
May 31, 2018
Click here to read the entire abstract
Pubmed Data
: Minerva Cardioangiol. 2018 Jun ;66(3):238-245. PMID:
29795059
Article Published Date
: May 31, 2018
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Pycnogenol (Pine Bark)
Diseases
:
Post-Thrombotic Syndrome
,
Venous Thrombosis
[+]
Propolis has radioprotective properties.
Aug 01, 2009
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2009 Aug;23(8):1159-68. PMID:
19165751
Article Published Date
: Aug 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Bee Propolis
,
Flavonoids
,
Polyphenols
Diseases
:
DNA damage
,
Radiation Induced Illness
Pharmacological Actions
:
Radioprotective
[+]
Pycnogenol has antidiabetic action in patients with type 2 diabetes.
Oct 08, 2004
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2004 Oct 8;75(21):2505-13. PMID:
15363656
Article Published Date
: Oct 08, 2004
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Pycnogenol (Pine Bark)
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Hypoglycemic Agents
Additional Keywords
:
Plant Extracts
[+]
Pycnogenol has therapeutic value in the prevention of jet lag in healthy and hypertensive patients.
Oct 01, 2008
Click here to read the entire abstract
Pubmed Data
: Minerva Cardioangiol. 2008 Oct;56(5 Suppl):3-9. PMID:
19597404
Article Published Date
: Oct 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Pycnogenol (Pine Bark)
Diseases
:
Brain Edema
,
Hypertension
,
Jet Lag
Pharmacological Actions
:
Platelet Aggregation Inhibitors
[+]
Pycnogenol improves allergic rhinitis symptoms when supplementation is started at least 5 weeks before the onset of the allergy season.
Aug 01, 2010
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2010 Aug;24(8):1115-9. PMID:
20549654
Article Published Date
: Aug 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Allergic Rhinitis
Pharmacological Actions
:
Anti-Allergic Agents
[+]
Pycnogenol improves diabetes control, lowers cardiovascular disease risk factors, and reduces the need for hypertension medication in type diabetic patients.
May 01, 2008
Click here to read the entire abstract
Pubmed Data
: Nutr Res. 2008 May;28(5):315-20. PMID:
19083426
Article Published Date
: May 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Pycnogenol (Pine Bark)
Diseases
:
Cardiovascular Diseases
,
Diabetes: Cardiovascular Illness
,
Diabetes Mellitus: Type 2
,
Hypertension
Pharmacological Actions
:
Antioxidants
,
Hypoglycemic Agents
Additional Keywords
:
Drug Sparing
,
Plant Extracts
[+]
Pycnogenol improves endothelial function of hypertensive patients.
Jan 02, 2004
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2004 Jan 2;74(7):855-62. PMID:
14659974
Article Published Date
: Jan 02, 2004
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Pycnogenol (Pine Bark)
Diseases
:
Endothelial Dysfunction
,
Hypertension
Pharmacological Actions
:
Platelet Aggregation Inhibitors
Additional Keywords
:
Plant Extracts
[+]
Pycnogenol is effective in treating symptoms associated with menopausal syndrome.
Dec 31, 2012
Click here to read the entire abstract
Pubmed Data
: J Reprod Med. 2013 Jan-Feb;58(1-2):39-46. PMID:
23447917
Article Published Date
: Dec 31, 2012
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Climacteric
,
Menopausal Syndrome
,
Postmenopausal Disorders: Insomnia
Pharmacological Actions
:
Analgesics
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Pycnogenol may alleviate adverse effects in oncologic treatment, e.g. deep vein thrombosis.
Jan 01, 2008
Click here to read the entire abstract
Pubmed Data
: Mol Vis. 2008;14:1288-92. Epub 2008 Jul 10. PMID:
18927527
Article Published Date
: Jan 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Pycnogenol (Pine Bark)
Diseases
:
Chemotherapy
,
Deep Vein Thrombosis
,
Radiation Induced Illness
Pharmacological Actions
:
Antineoplastic Agents
Additional Keywords
:
Drug Side Effect Attenuation
[+]
Pycnogenol may be of value in treatment of MSU crystal-induced arthritis through its anti-inflammatory and anti-nitrosative activities.
Feb 14, 2012
Click here to read the entire abstract
Pubmed Data
: Free Radic Biol Med. 2012 Feb 15 ;52(4):765-74. Epub 2011 Dec 13. PMID:
22198264
Article Published Date
: Feb 14, 2012
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Gout
,
Hyperuricemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
[+]
Pycnogenol prevents damage in the microcirculation of hypertensive patients, and allows the dose of anti-hypertensive drugs to be reduced in most patients.
Oct 01, 2006
Click here to read the entire abstract
Pubmed Data
: Clin Appl Thromb Hemost. 2006 Oct;12(4):440-4. PMID:
17000888
Article Published Date
: Oct 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Pycnogenol (Pine Bark)
Diseases
:
Edema
,
Hypertension
Pharmacological Actions
:
Antihypertensive Agents
,
Calcium Channel Blockers
,
Platelet Aggregation Inhibitors
Additional Keywords
:
Drug-Plant-Vitamin Synergies
,
Drug Sparing
[+]
Pycnogenol relieves symptoms of tinnitus by improving cochlear flow.
Jun 01, 2010
Click here to read the entire abstract
Pubmed Data
: Panminerva Med. 2010 Jun;52(2 Suppl 1):63-7. PMID:
20657537
Article Published Date
: Jun 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Tinnitus
[+]
Pycnogenol supplementation benefits human skin by increasing skin hydration and skin elasticity.
Dec 31, 2011
Click here to read the entire abstract
Pubmed Data
: Skin Pharmacol Physiol. 2012 ;25(2):86-92. Epub 2012 Jan 21. PMID:
22270036
Article Published Date
: Dec 31, 2011
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Aging Skin
,
Wrinkles
[+]
Quercetin and rutin may ameliorate insecticide induced oxidative stress in human erythrocytes.
Mar 01, 2010
Click here to read the entire abstract
Pubmed Data
: Toxicol In Vitro. 2010 Mar;24(2):460-4. Epub 2009 Oct 13. PMID:
19833193
Article Published Date
: Mar 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Quercetin
,
Rutin
Diseases
:
Oxidative Stress
,
Pesticide Toxicity
Pharmacological Actions
:
Antioxidants
[+]
Regular consumption of a chocolate rich in flavanols confers significant photoprotection and can thus be effective at protecting human skin from harmful UV effects.
Sep 01, 2009
Click here to read the entire abstract
Pubmed Data
: Lett Appl Microbiol. 2009 Sep;49(3):354-60. Epub 2009 Jul 14. PMID:
19735513
Article Published Date
: Sep 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Chocolate
,
Flavonoids
Diseases
:
Skin Diseases: Photo-Aging
,
Sunburn
[+]
Regular moderate intake of red wine is linked to a better women's sexual health.
Sep 30, 2009
Click here to read the entire abstract
Pubmed Data
: J Sex Med. 2009 Oct ;6(10):2772-7. Epub 2009 Jul 21. PMID:
19627470
Article Published Date
: Sep 30, 2009
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
,
Wine
Diseases
:
Endothelial Dysfunction
,
Libido: Low
,
Sexaul Dysfunction
[+]
Results showed a direct association between the intake of red wine, a source of stilbenes, and the relative abundance of bacteroides.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2016 Jan ;7(1):104-9. PMID:
26437130
Article Published Date
: Dec 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Coffee
,
Flavonoids
,
Red Wine Extract
,
Stilbenes
Diseases
:
Allergic Rhinitis
,
Asthma
[+]
Rheumatoid patients subjectively benefited from the vegan diet rich in antioxidants, lactobacilli and fibre.
Nov 29, 2000
Click here to read the entire abstract
Pubmed Data
: Toxicology. 2000 Nov 30 ;155(1-3):45-53. PMID:
11156742
Article Published Date
: Nov 29, 2000
Study Type
: Human Study
Additional Links
Substances
:
Carotenoids
,
Fiber
,
Flavonoids
,
Lignans
Diseases
:
Inflammation
,
Rheumatoid Arthritis
Therapeutic Actions
:
Dietary Modification: Vegetarian
Pharmacological Actions
:
Antioxidants
[+]
Sea buckthorn leaf extracts protect neuronal PC-12 cells from oxidative stress.
Jul 27, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Microbiol Biotechnol. 2017 Jul 28 ;27(7):1257-1265. PMID:
28535611
Article Published Date
: Jul 27, 2017
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Kaempferol
,
Quercetin
,
Sea buckthorn
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Neuroprotective Agents
Additional Keywords
:
Plant Extracts
[+]
Short- and long-term black tea consumption reverses endothelial dysfunction in patients with coronary artery disease.
Jul 10, 2001
Click here to read the entire abstract
Pubmed Data
: Circulation. 2001 Jul 10;104(2):151-6. PMID:
11447078
Article Published Date
: Jul 10, 2001
Study Type
: Human Study
Additional Links
Substances
:
Black Tea
,
Flavonoids
,
Green Tea
,
Tea
Diseases
:
Coronary Artery Disease
,
Endothelial Dysfunction
Pharmacological Actions
:
Antioxidants
,
Vasodilator Agents
Additional Keywords
:
Plant Extracts
[+]
Short-term cocoa consumption signficantly reduces blood cholesterol.
Jul 01, 2010
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2010 Jul;92(1):218-25. Epub 2010 May 26. PMID:
20504978
Article Published Date
: Jul 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Cardiovascular Diseases
,
High Cholesterol
Pharmacological Actions
:
Anticholesteremic Agents
[+]
Tea consumption reduces the risk of biliary tract and gallbladder diseases.
Nov 01, 2005
Click here to read the entire abstract
Pubmed Data
: Zhonghua Zhong Liu Za Zhi. 2005 Nov;27(11):667-71. PMID:
16438888
Article Published Date
: Nov 01, 2005
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Green Tea
,
Polyphenols
,
Tea: Black
Diseases
:
Bile Duct Cancer
,
Gallbladder Cancer
Pharmacological Actions
:
Chemopreventive
[+]
The consumption of some flavonoids may interact with exposure to phthalates on the risk of breast cancer.
Oct 31, 2016
Click here to read the entire abstract
Pubmed Data
: Environ Int. 2016 Nov ;96:167-172. Epub 2016 Aug 28. PMID:
27690147
Article Published Date
: Oct 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Vegetables: All
Diseases
:
Breast Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Risk Reduction
Problem Substances
:
Phthalates
[+]
The flavonoids hesperidin and diosmin reduce bleeding and pain after stapled hemorrhoidopexy.
Aug 01, 2005
Click here to read the entire abstract
Pubmed Data
: Wien Klin Wochenschr. 2005 Aug;117(15-16):558-60. PMID:
16158207
Article Published Date
: Aug 01, 2005
Study Type
: Human Study
Additional Links
Substances
:
Diosmin
,
Flavonoids
,
Hesperidin
Diseases
:
Hemorrhoids
,
Postoperative Recovery
Pharmacological Actions
:
Analgesics
,
Anti-Inflammatory Agents
[+]
The high intake of flavanol-rich cocoa by the Kuna Indians may be responsible for their low blood pressure.
Jan 01, 2006
Click here to read the entire abstract
Pubmed Data
: J Cardiovasc Pharmacol. 2006;47 Suppl 2:S103-9; discussion 119-21. PMID:
16794446
Article Published Date
: Jan 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Catechin
,
Flavonoids
Diseases
:
Hypertension
Additional Keywords
:
Proanthocyanidins
[+]
The intake of flavonoids showed an inverse association with risk of cardiovascular events.
Oct 03, 2018
Click here to read the entire abstract
Pubmed Data
: Nutr Metab Cardiovasc Dis. 2018 Oct 4. Epub 2018 Oct 4. PMID:
30459074
Article Published Date
: Oct 03, 2018
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Cardiovascular Diseases
Additional Keywords
:
Risk Reduction
[+]
The intake of flavonoids, particularly from solid fruit, is associated with better pulmonary function in patients with COPD.
Jul 01, 2001
Click here to read the entire abstract
Pubmed Data
: Am J Respir Crit Care Med. 2001 Jul 1;164(1):61-4. PMID:
11435239
Article Published Date
: Jul 01, 2001
Study Type
: Human Study
Additional Links
Substances
:
Catechin
,
Flavonoids
,
Fruit: All
Diseases
:
Chronic Obstructive Pulmonary Disease
[+]
The Mediterranean diet, which includes a combination of antioxidant compounds and flavonoid-rich foods, appears effective to decrease LDL particle oxidizability, which reduces the risk for cardiovascular disease.
Oct 01, 2006
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2006 Oct;17(10):645-58. Epub 2006 Feb 3. PMID:
16517144
Article Published Date
: Oct 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Arteriosclerosis
,
Cardiovascular Diseases
,
Cholesterol: Oxidation
Therapeutic Actions
:
Dietary Modification: Mediterranean Diet
Pharmacological Actions
:
Antioxidants
[+]
The oral intake of Pycnogenol down-regulated the gene expression of various cartilage degradation markers in the patients' chondrocytes.
Dec 15, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2017 Dec 16 ;17(1):537. Epub 2017 Dec 16. PMID:
29246219
Article Published Date
: Dec 15, 2017
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Osteoarthritis: Knee
Pharmacological Actions
:
Interleukin-1 beta downregulation
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
[+]
The regular consumption of cocoa products containing flavanols may reduce risk of cardiovascular disease.
Jan 01, 2008
Click here to read the entire abstract
Pubmed Data
: Asia Pac J Clin Nutr. 2008;17 Suppl 1:284-7. PMID:
18296357
Article Published Date
: Jan 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Cardiovascular Diseases
,
Endothelial Dysfunction
,
Hypertension
Additional Keywords
:
Risk Reduction
[+]
The results of the present study add to the current literature further evidence of the association between higher flavonoid intake and decreased body weight.
Mar 25, 2018
Click here to read the entire abstract
Pubmed Data
: Int J Food Sci Nutr. 2018 Mar 26:1-10. Epub 2018 Mar 26. PMID:
29575952
Article Published Date
: Mar 25, 2018
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Obesity
Additional Keywords
:
Anti-Obesity Agents
,
Flavonoids
,
obesity
[+]
These findings suggest a protective association between dietary intake of flavonoids and the likelihood of having age-related macular degeneration.
Jul 05, 2018
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2018 Jul 6. Epub 2018 Jul 6. PMID:
29982448
Article Published Date
: Jul 05, 2018
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Orange
Diseases
:
Macular Degeneration
Additional Keywords
:
Risk Reduction
[+]
These findings suggest that the intake of some flavonoids may reduce Parkinson’s disease risk.
Apr 09, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Neurology. 2012 Apr 10 ;78(15):1138-45. Epub 2012 Apr 4. PMID:
22491871
Article Published Date
: Apr 09, 2012
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Flavonoids
Diseases
:
Parkinson's Disease
Additional Keywords
:
Risk Reduction
[+]
These results indicate that flavonoid intake is associated with lower head and neck cancer risk.
Jul 18, 2017
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2017 Jul 19. Epub 2017 Jul 19. PMID:
28724656
Article Published Date
: Jul 18, 2017
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Flavonoids
Diseases
:
Head and Neck Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Risk Reduction
[+]
This pilot study provides the first evidence of miRNA modulation by diet and other factors, that can be detected consistently in both plasma and stools samples.
Aug 31, 2014
Click here to read the entire abstract
Pubmed Data
: Mutagenesis. 2014 Sep ;29(5):385-91. PMID:
25150024
Article Published Date
: Aug 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Pharmacological Actions
:
MicroRNA modulator
Additional Keywords
:
Dietary Concentrations
,
Epigenetic Modification
[+]
Topical diosmin has therapeutic effects in the treatment of acute hemorrhoid pathology.
May 01, 1988
Click here to read the entire abstract
Pubmed Data
: Minerva Med. 1988 May;79(5):387-90. PMID:
3287228
Article Published Date
: May 01, 1988
Study Type
: Human Study
Additional Links
Substances
:
Diosmin
,
Flavonoids
Diseases
:
Hemorrhoids
[+]
Wine consumption reduces TNF-apha-induced adhesion of monocytes to endothelial cells.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: Cell Physiol Biochem. 2010;26(3):471-82. Epub 2010 Aug 24. PMID:
15213052
Article Published Date
: Jan 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
,
Wine
Diseases
:
Arteriosclerosis
,
Heart Disease: Ischemic
Pharmacological Actions
:
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Apigenin highly upregulated the expression of cytokine genes and induced apoptosis in human pancreatic cancer cells.
Nov 30, 2013
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2013 Dec ;57(12):2112-27. Epub 2013 Aug 14. PMID:
23943362
Article Published Date
: Nov 30, 2013
Study Type
: Human In Vitro
Additional Links
Substances
:
Apigenin
,
Flavonoids
Diseases
:
Inflammation
,
Pancreatic Cancer
Pharmacological Actions
:
Anti Inflammatory
,
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
,
Glycogen synthase kinase-3beta (GSK-3beta) Inhibitor
,
NF-kappaB Inhibitor
Additional Keywords
:
Epigenetic Modification In Cancer
[+]
chokeberry juice inhibited Caco-2 cell proliferation by causing G(2)/M cell cycle arrest.
Mar 31, 2007
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2007 Apr ;18(4):259-71. Epub 2006 Jul 24. PMID:
16860979
Article Published Date
: Mar 31, 2007
Study Type
: Human In Vitro
Additional Links
Substances
:
Chokeberry
,
Flavonoids
,
Polyphenols
Diseases
:
Colorectal Cancer
,
Colorectal Cancer: Prevention
Pharmacological Actions
:
Antiproliferative
,
Cell cycle arrest
,
Chemopreventive
[+]
"Chrysin abrogates early hepatocarcinogenesis and induces apoptosis in N-nitrosodiethylamine-induced preneoplastic nodules in rats."
Feb 15, 2011
Click here to read the entire abstract
Pubmed Data
: Toxicol Appl Pharmacol. 2011 Feb 15 ;251(1):85-94. Epub 2010 Dec 15. PMID:
21167192
Article Published Date
: Feb 15, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Liver Cancer: Prevention
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antiproliferative
,
Apoptotic
,
Cyclooxygenase 2 Inhibitors
,
Tumor Suppressor Protein p53 Upregulation
[+]
A cocoa diet enhances thymus antioxidant defenses and influences thymocyte differentiation.
Aug 08, 2007
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2007 Aug 8;55(16):6431-8. Epub 2007 Jul 14. PMID:
17630760
Article Published Date
: Aug 08, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Catechin
,
Flavonoids
,
Polyphenols
Diseases
:
Low Immune Function: Thymus Dysfunction
Pharmacological Actions
:
Antioxidants
,
Immunomodulatory
[+]
A cocoa-enriched diet prevents gingival oxidative stress in experimental periodontitis.
Nov 01, 2009
Click here to read the entire abstract
Pubmed Data
: J Periodontol. 2009 Nov;80(11):1799-808. PMID:
19905949
Article Published Date
: Nov 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Cocoa
,
Flavonoids
,
Polyphenols
Diseases
:
Periodontitis
Pharmacological Actions
:
Antioxidants
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
A mixture of phytochemicals naturally present in foods represents a plausible chemopreventive agent for colorectal cancer.
May 31, 2011
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Prev Res (Phila). 2011 Jun ;4(6):907-15. Epub 2011 Mar 7. PMID:
21383028
Article Published Date
: May 31, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Apple Polyphenols
,
Apples
,
Flavonoids
Diseases
:
Colon Polyps
,
Colorectal Cancer
,
Colorectal Cancer: Prevention
Pharmacological Actions
:
Antioxidants
,
Chemopreventive
Additional Keywords
:
Dietary Concentrations
[+]
A natural flavonoid present in unripe plantain banana pulp (Musa sapientum L. var. paradisiaca) protects the gastric mucosa from aspirin-induced erosions.
Jun 01, 1999
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 1999 Jun;65(3):283-8. PMID:
10404428
Article Published Date
: Jun 01, 1999
Study Type
: Animal Study
Additional Links
Substances
:
Banana
,
Flavonoids
Diseases
:
Aspirin-Induced Toxicity
,
NSAID-induced toxicity
Pharmacological Actions
:
Anti-Ulcer Agents
[+]
A polyphenol extract from red grapes redues fat content in an animal model of non-alcoholic liver disease.
Dec 01, 2010
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2010 Dec;104(12):1760-70. Epub 2010 Aug 2. PMID:
20673376
Article Published Date
: Dec 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Grape
,
Polyphenols
,
Resveratrol
Diseases
:
Fatty Liver
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Acute cocoa flavanol improves cerebral oxygenation without enhancing executive function at rest or after exercise.
Nov 30, 2016
Click here to read the entire abstract
Pubmed Data
: Appl Physiol Nutr Metab. 2016 Dec ;41(12):1225-1232. Epub 2016 Aug 5. PMID:
27849355
Article Published Date
: Nov 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Cocoa
,
Flavonoids
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Brain-derived neurotrophic factor modulator
[+]
Allomelanins suppress the tumor cell growth in vitro and in vivo.
Aug 01, 1997
Click here to read the entire abstract
Pubmed Data
: Cancer Biother Radiopharm. 1997 Aug;12(4):273-6. PMID:
10851475
Article Published Date
: Aug 01, 1997
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Lymphoma
Pharmacological Actions
:
Cell cycle arrest
Additional Keywords
:
Food Colors: Black
,
Food Colors: Purple
[+]
An aqueous decoction of mango flowers has potential gastroprotective and ulcer-healing properties.
Aug 01, 2004
Click here to read the entire abstract
Pubmed Data
: Planta Med. 2004 Aug;70(8):745-52. PMID:
16500058
Article Published Date
: Aug 01, 2004
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Flowers
,
Mango
,
Polyphenols
Diseases
:
Gastric Ulcer
Pharmacological Actions
:
Anti-Ulcer Agents
,
Cyclooxygenase Inhibitors
Additional Keywords
:
Plant Extracts
[+]
An extract of aged black garlic significantly suppressed IgE-induced anaphylaxis in a (PCA) model.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Med Food. 2014 Jan ;17(1):92-102. PMID:
24456359
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Garlic: Aged
,
Polyphenols
Diseases
:
Allergies
,
Anaphylaxis
,
IgE-Mediated Hypersensitivity
Pharmacological Actions
:
Anti-Allergic Agents
,
Anti-Inflammatory Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Anthocyanin rich bilberry and blackcurrant diets favorably modulate altered amyloid precursor protein processing and alleviate behavioral abnormalities in a mouse model of AD.
Dec 31, 2012
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2013 Jan ;24(1):360-70. Epub 2012 Sep 17. PMID:
22995388
Article Published Date
: Dec 31, 2012
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Anthocyanins
,
Bilberry
,
Black Currant
,
Flavonoids
,
Quercetin
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Plant Extracts
[+]
Anxiolytic activity of a phytochemically characterized Passiflora incarnata extract is mediated via the GABAergic system.
Nov 30, 2008
Click here to read the entire abstract
Pubmed Data
: Planta Med. 2008 Dec ;74(15):1769-73. Epub 2008 Nov 12. PMID:
19006051
Article Published Date
: Nov 30, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Passion Flower
Diseases
:
Anxiety
Pharmacological Actions
:
Anti-Anxiety Agents
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Apigenin and myricetin exhibited a protective and promising preventive strategy against cisplatin-induced nephrotoxicity.
Nov 30, 2017
Click here to read the entire abstract
Pubmed Data
: Pharm Biol. 2017 Dec ;55(1):766-774. PMID:
28064632
Article Published Date
: Nov 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Apigenin
,
Flavonoids
,
Myricetin
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Oxidative Stress
Pharmacological Actions
:
Chemoprotective Agents
,
Cyclooxygenase 1 Inhibitor
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Apigenin has a protective role against lipid peroxidation and oxidative stress associated with the development of liver cancer in rats.
Dec 01, 2009
Click here to read the entire abstract
Pubmed Data
: Atherosclerosis. 2009 Dec;207(2):420-7. Epub 2009 May 22. PMID:
15185843
Article Published Date
: Dec 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Apigenin
,
Flavonoids
Diseases
:
Liver Cancer
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Apigenin is a bioflavonoid that inhibits hypoxia-activated pathways linked to cancer progression in human prostate cancer
Sep 01, 2008
Click here to read the entire abstract
Pubmed Data
: Mol Carcinog. 2008 Sep;47(9):686-700. PMID:
18240292
Article Published Date
: Sep 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Apigenin
,
Flavonoids
Diseases
:
Hypoxia
,
Prostate Cancer
Pharmacological Actions
:
Vascular Endothelial Growth Factor A Inhibitor
[+]
Apple fibers and polyphenols may play a role in preventing atherosclerosis by decreasing uric acid plasma level.
Apr 01, 2007
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2007 Apr;14(4):280-4. Epub 2007 Feb 12. PMID:
18558693
Article Published Date
: Apr 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Apples
,
Fiber
,
Flavonoids
,
Polyphenols
Diseases
:
Atherosclerosis
,
Hyperuricemia
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Plant Extracts
[+]
Apples may exert their colon cancer protective effects through favorably altering gene patterns resulting in protection of cells against toxicological insults.
Jun 15, 2008
Click here to read the entire abstract
Pubmed Data
: Int J Cancer. 2008 Jun 15;122(12):2647-55. PMID:
18351577
Article Published Date
: Jun 15, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Apples
,
Flavonoids
,
Polyphenols
Diseases
:
Colon Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Epigenetic Modification
[+]
Apples rich polyphenols reduce colonic inflammation in rats.
Dec 01, 2009
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2009 Dec;102(11):1620-8. Epub 2009 Jul 22. PMID:
19622193
Article Published Date
: Dec 01, 2009
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Apples
,
Flavonoids
,
Polyphenols
Diseases
:
Inflammatory Bowel Diseases
,
Irritable Bowel Syndrome
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
[+]
Baccharis dracunculifolia, the main botanical source of Brazilian green propolis, displays antiulcer activity.
Apr 01, 2007
Click here to read the entire abstract
Pubmed Data
: J Pharm Pharmacol. 2007 Apr;59(4):603-8. PMID:
17430646
Article Published Date
: Apr 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Baccharis dracunculifolia
,
Bee Propolis
,
Flavonoids
Diseases
:
Gastric Ulcer
Pharmacological Actions
:
Anti-Ulcer Agents
Additional Keywords
:
Natural Substances Versus Drugs
,
Plant Extracts
[+]
Banana prevents lipid oxidation in rats.
Dec 01, 2005
Click here to read the entire abstract
Pubmed Data
: Indian J Med Res. 2005 Dec;122(6):540-6. PMID:
16518007
Article Published Date
: Dec 01, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Banana
,
Flavonoids
,
Plantain
Diseases
:
Cholesterol: Oxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
[+]
Blackberries improve motor and cognitive performance in aged rats.
Jun 01, 2009
Click here to read the entire abstract
Pubmed Data
: Nutr Neurosci. 2009 Jun;12(3):135-40. PMID:
19356316
Article Published Date
: Jun 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Blackberry
,
Flavonoids
,
Polyphenols
Diseases
:
Aging: Brain
,
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
[+]
Blue skullcap (S. lateriflora) has anticonvulsant activity.
May 01, 2009
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2009 May;16(5):485-93. Epub 2008 Sep 10. PMID:
18786819
Article Published Date
: May 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Skullcap: Blue
Diseases
:
Convulsions
,
Seizures
Pharmacological Actions
:
Anticonvulsants
Additional Keywords
:
Plant Extracts
[+]
Blueberry inhibits the growth and metastatic potential of triple negative breast cancer in vitro and in vivo.
May 01, 2010
Click here to read the entire abstract
Pubmed Data
: Cancer Res. 2010 May 1;70(9):3594-605. Epub 2010 Apr 13. PMID:
20388778
Article Published Date
: May 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Blueberry
,
Flavonoids
,
Polyphenols
Diseases
:
Breast Cancer
,
Breast Cancer: Metastatic
,
Breast Cancer: Triple Negative
Pharmacological Actions
:
Apoptotic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
Additional Keywords
:
Plant Extracts
[+]
Both curcumin and its metabolite tetrahydrocurcumin exert neuroprotection against chemically-induced neurotoxicity.
Apr 01, 2008
Click here to read the entire abstract
Pubmed Data
: Inflammopharmacology. 2008 Apr;16(2):96-9. PMID:
18408903
Article Published Date
: Apr 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Flavonoids
,
Polyphenols
,
Tetrahydrocurcumin
Diseases
:
Neurodegenerative Diseases
,
Parkinson's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Buckwheat polyphenols protective effect against long-lasting impairment of spatial memory associated with hippocampal neuronal damage in rats subjected to repeated cerebral ischemia.
Apr 01, 2004
Click here to read the entire abstract
Pubmed Data
: J Pharmacol Sci. 2004 Apr;94(4):393-402. PMID:
15107579
Article Published Date
: Apr 01, 2004
Study Type
: Animal Study
Additional Links
Substances
:
Buckwheat
,
Flavonoids
,
Polyphenols
Diseases
:
Brain Injury: Hippocampal Damage
,
Cerebral Ischemia
,
Memory Disorders
Pharmacological Actions
:
Neuroprotective Agents
[+]
Buckwheat sprouts have an anti-inflammatory effect in lipopolysaccharide-activated human colon cancer cells and mice.
Dec 01, 2008
Click here to read the entire abstract
Pubmed Data
: Biosci Biotechnol Biochem. 2008 Dec;72(12):3148-57. Epub 2008 Dec 7. PMID:
19060399
Article Published Date
: Dec 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Buckwheat
,
Flavonoids
,
Sprouts
Diseases
:
Colon Cancer
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Plant Extracts
[+]
C. spinosa has the potential to down regulate inflammation-involved genes in Alzheimer's disease.
Oct 24, 2016
Click here to read the entire abstract
Pubmed Data
: Nutr Neurosci. 2016 Oct 25:1-8. Epub 2016 Aug 25. PMID:
27778760
Article Published Date
: Oct 24, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Capparis spinosa (caper)
,
Flavonoids
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Gene Expression Regulation
[+]
Cacao polyphenol extract suppresses dioxin-induced toxicity in mice.
Jan 01, 1993
Click here to read the entire abstract
Pubmed Data
: Clin Investig. 1993;71(8 Suppl):S134-6. PMID:
18928297
Article Published Date
: Jan 01, 1993
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Dioxin Toxicity
Additional Keywords
:
Plant Extracts
[+]
Celery extract protects against pesticide-induced toxicity.
Nov 01, 2011
Click here to read the entire abstract
Pubmed Data
: Hum Exp Toxicol. 2011 Nov 1. Epub 2011 Nov 1. PMID:
22045891
Article Published Date
: Nov 01, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Celery
,
Flavonoids
Diseases
:
Chemically-Induced Liver Damage
,
Pesticide-Induced Toxicity: Organophosphates
,
Pesticide Toxicity
Pharmacological Actions
:
Hepatoprotective
Problem Substances
:
Dichlorvos
,
Organophosphates
,
Pesticides
Adverse Pharmacological Actions
:
Hepatotoxic
,
Oxidant
[+]
Chokeberry fruit derivatives may act as a promising supplementary therapeutic option in the prevention and treatment of disorders occurring in metabolic syndrome, as well as their complications.
Nov 30, 2008
Click here to read the entire abstract
Pubmed Data
: Plant Foods Hum Nutr. 2008 Dec ;63(4):176-82. Epub 2008 Aug 23. PMID:
18726160
Article Published Date
: Nov 30, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
,
Chokeberry
,
Flavonoids
,
Polyphenols
Diseases
:
Diabetes Mellitus: Type 2: Prevention
,
Hyperlipidemia
,
Lipid Peroxidation
,
Metabolic Syndrome X
Pharmacological Actions
:
Alpha-glucosidase inhibitor
,
Hypoglycemic Agents
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Chronic but not acute treatment with the Ginkgo biloba extract EGb 761(R) increased dopaminergic transmission in the rat prefrontal cortex.
Feb 01, 2010
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Br J Pharmacol. 2010 Feb 1 ;159(3):659-68. Epub 2010 Jan 25. PMID:
20105177
Article Published Date
: Feb 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Ginkgo biloba
Diseases
:
Dopamine Deficiency
Pharmacological Actions
:
Dopaminergic
Additional Keywords
:
Plant Extracts
[+]
Cocoa extract has a neuroprotective action.
Feb 01, 2009
Click here to read the entire abstract
Pubmed Data
: Eur J Nutr. 2009 Feb;48(1):54-61. Epub 2008 Nov 29. PMID:
19043659
Article Published Date
: Feb 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Catechin
,
Flavonoids
Diseases
:
Neuroblastoma
,
Oxidative Stress
Pharmacological Actions
:
Apoptotic
,
Neuroprotective Agents
[+]
Cocoa extract has a protective efect on experimentally induced benign prostatic hyperplasia.
Dec 01, 2007
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2007 Dec;10(4):628-35. PMID:
18158833
Article Published Date
: Dec 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Prostatic Hyperplasia: Benign
Additional Keywords
:
Plant Extracts
[+]
Cocoa flavanol and procyanidin supplementation inhibits platelet function.
Jun 01, 2003
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2003 Jun;77(6):1466-73. PMID:
12791625
Article Published Date
: Jun 01, 2003
Study Type
: Animal Study
Additional Links
Substances
:
Catechin
,
Flavonoids
Diseases
:
Clotting
Pharmacological Actions
:
Platelet Aggregation Inhibitors
Additional Keywords
:
Proanthocyanidins
[+]
Cocoa polyphenol has an antidepressant-like effect in rats.
Dec 01, 2008
Click here to read the entire abstract
Pubmed Data
: Nutr Neurosci. 2008 Dec;11(6):269-76. PMID:
19000380
Article Published Date
: Dec 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Depression
Pharmacological Actions
:
Antidepressive Agents
Additional Keywords
:
Plant Extracts
[+]
Cocoa polyphenols may inhibit tumor promotion through antioxidant and antiinflammatory mechanisms.
May 01, 2006
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2006 May;136(5):1150-5. PMID:
16614396
Article Published Date
: May 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Tumors
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
[+]
Compounds in oats are bioavailable and act synergistically with vitamin C enhance hamster and human LDL resistance to oxidation.
Jun 01, 2004
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2004 Jun;134(6):1459-66. PMID:
15173412
Article Published Date
: Jun 01, 2004
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Oats
,
Polyphenols
,
Vitamin C
Diseases
:
Cholesterol: Oxidation
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Natural Substance Synergy
[+]
Consumption of curcumin elevates fecal immunoglobulin A, an index of intestinal immune function, in rats fed a high-fat diet.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: J Nutr Sci Vitaminol (Tokyo). 2010;56(1):68-71. PMID:
20354349
Article Published Date
: Jan 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Flavonoids
,
Polyphenols
Diseases
:
IgA Deficiency
,
Immune Disorders: Low Immune Function
Pharmacological Actions
:
Immunomodulatory
Additional Keywords
:
Plant Extracts
[+]
Consumption of some polyphenols reduces fecal deoxycholic acid and lithocholic acid, the secondary bile acids of risk factors of colon cancer.
Sep 23, 2009
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2009 Sep 23;57(18):8587-90. PMID:
19711910
Article Published Date
: Sep 23, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Caffeic Acid
,
Curcumin
,
Ellagic Acid
,
Flavonoids
,
Polyphenols
,
Rutin
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
[+]
Corn silk has potential as a therapeutic treatment for diabetic conditions.
Dec 22, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2015 Dec 23 ;21(1):E7. Epub 2015 Dec 23. PMID:
26703560
Article Published Date
: Dec 22, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Corn Silk
,
Flavonoids
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Antioxidants
,
Hypoglycemic Agents
[+]
Cranberry flavonoids prevent toxic rat liver mitochondrial damage in vivo and scavenge free radicals in vitro.
May 31, 2015
Click here to read the entire abstract
Pubmed Data
: Cell Biochem Funct. 2015 Jun ;33(4):202-10. Epub 2015 May 11. PMID:
25962994
Article Published Date
: May 31, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Cranberry
,
Flavonoids
Diseases
:
Lipid Peroxidation
,
Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Curcumin exhibits chemopreventive properties in hematogenous breast cancer metastases in immunodeficient mice.
Jan 01, 2007
Click here to read the entire abstract
Pubmed Data
: Cell Physiol Biochem. 2007;19(1-4):137-52. PMID:
17310108
Article Published Date
: Jan 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Flavonoids
,
Polyphenols
Diseases
:
Breast Cancer
,
Cancer Metastasis
,
Immune Disorders: Low Immune Function
,
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Apoptotic
,
NF-kappaB Inhibitor
[+]
Curcuminoids positively modulates oxidative damage and mitochondrial dysfunction in diabetic rat brain.
Nov 01, 2008
Click here to read the entire abstract
Pubmed Data
: Free Radic Res. 2008 Nov;42(11-12):999-1005. PMID:
19031318
Article Published Date
: Nov 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Flavonoids
,
Polyphenols
Diseases
:
Diabetes: Cognitive Dysfunction
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
[+]
Cyperus rotundus suppresses AGE formation and protein oxidation in a model of fructose-mediated protein glycoxidation.
Dec 01, 2007
Click here to read the entire abstract
Pubmed Data
: Int J Biol Macromol. 2007 Dec 1;41(5):572-8. Epub 2007 Jul 27. PMID:
17765965
Article Published Date
: Dec 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Cyperus rotundus
,
Flavonoids
,
Polyphenols
Diseases
:
Advanced Glycation End products (AGE)
,
Fructose-Induced Toxicity
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Plant Extracts
[+]
Dietary tricin, a flavone present in rice, oats, barley, and wheat inhibits inflammation-related mouse colon carcinogenesis.
Dec 01, 2009
Click here to read the entire abstract
Pubmed Data
: Cancer Prev Res (Phila Pa). 2009 Dec;2(12):1031-8. Epub 2009 Nov 24. PMID:
19934339
Article Published Date
: Dec 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Grains: All
,
Oats
,
Rice
,
Tricin
Diseases
:
Colon Cancer
,
Inflammation
Pharmacological Actions
:
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Dietary unripe apple polyphenol inhibits the development of food allergies in the mouse model.
Aug 15, 2005
Click here to read the entire abstract
Pubmed Data
: FEBS Lett. 2005 Aug 15;579(20):4485-91. PMID:
16081068
Article Published Date
: Aug 15, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Apples
,
Flavonoids
,
Polyphenols
,
Tannic Acid
Diseases
:
Food Allergies
Additional Keywords
:
Proanthocyanidins
[+]
Effect of Citrus bergamia juice on human neuroblastoma cells in vitro and in metastatic xenograft models.
May 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Fitoterapia. 2014 Jun ;95:83-92. Epub 2014 Mar 2. PMID:
24594241
Article Published Date
: May 31, 2014
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Bergamot orange
,
Flavonoids
Diseases
:
Cancer Metastasis
,
Neuroblastoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
[+]
Eggplant flavonoids exhibit cholesterol-lowering activity in rats.
Jan 01, 1997
Click here to read the entire abstract
Pubmed Data
: Plant Foods Hum Nutr. 1997;51(4):321-30. PMID:
9650725
Article Published Date
: Jan 01, 1997
Study Type
: Animal Study
Additional Links
Substances
:
Eggplant
,
Flavonoids
Diseases
:
Hypercholesterolemia
[+]
Embelia ribes has a cardioprotective effect against isoproterenol-induced myocardial infarcation in rats.
Jan 01, 2008
Click here to read the entire abstract
Pubmed Data
: Indian J Exp Biol. 2008 Jan;46(1):35-40. PMID:
18697569
Article Published Date
: Jan 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Embelia ribes
,
Flavonoids
,
Polyphenols
Diseases
:
Myocardial Infarction
Pharmacological Actions
:
Antioxidants
,
Cardioprotective
Additional Keywords
:
Plant Extracts
[+]
Epicatechin flavonoid compound cause beta cell regeneration. - Article 1
Dec 13, 1982
Click here to read the entire abstract
Pubmed Data
: Life Sci. 1982 Dec 13;31(24):2693-7. PMID:
6759833
Article Published Date
: Dec 13, 1982
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Diabetes Mellitus: Type 1
Additional Keywords
:
Beta Cell Regeneration
[+]
Epimedium flavonoids slow immunosenescence via NF-kappaB down-regulation.
Jul 01, 2006
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhong Xi Yi Jie He Za Zhi. 2006 Jul;26(7):620-4. PMID:
16983917
Article Published Date
: Jul 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Epimedium
,
Flavonoids
Diseases
:
Aging: Immunosenecence
Pharmacological Actions
:
NF-kappaB Inhibitor
[+]
Fenugreek (Trigonella foenum graecum) seed polyphenols protects the liver from alcohol toxicity.
Apr 01, 2007
Click here to read the entire abstract
Pubmed Data
: Pharmazie. 2007 Apr;62(4):299-304. PMID:
17484288
Article Published Date
: Apr 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Fenugreek
,
Flavonoids
,
Polyphenols
Diseases
:
Alcohol Toxicity
,
Alcoholic Liver Disease
Pharmacological Actions
:
Phase II Detoxification Enzyme Inducer
Additional Keywords
:
Plant Extracts
[+]
Fig fruit has antioxidant and immunostimulatory properties.
Jun 01, 2009
Click here to read the entire abstract
Pubmed Data
: Plant Foods Hum Nutr. 2009 Jun;64(2):167-73. PMID:
19466553
Article Published Date
: Jun 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Fig
,
Flavonoids
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Immunomodulatory
Additional Keywords
:
Plant Extracts
[+]
Flavonoids can restore Brahma functionality by reversing acetylation.
May 28, 2014
Click here to read the entire abstract
Pubmed Data
: Carcinogenesis. 2014 May 29. Epub 2014 May 29. PMID:
24876151
Article Published Date
: May 28, 2014
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Diosmin
,
Flavonoids
,
Rutin
Diseases
:
Cancers: All
,
Lung Cancer
Pharmacological Actions
:
Anti-Tumor
,
Antiproliferative
,
Chemopreventive
Additional Keywords
:
Epigenetic Modification In Cancer
,
Reactivation Of Tumor Suppressor Gene
[+]
Flavonoids could be used as protective agents against oxidative stress induced by gentamicin.
Jul 31, 2018
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2018 Aug ;118:294-302. Epub 2018 May 26. PMID:
29758313
Article Published Date
: Jul 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Luteolin
Diseases
:
Chemotherapy-Induced Toxicity: Gentamicin
Pharmacological Actions
:
Antioxidants
Problem Substances
:
Gentamicin
[+]
Flavonoids extracted from leaves of Diospyros kaki are potential therapeutic agents for Alzheimer's disease.
May 01, 2018
Click here to read the entire abstract
Pubmed Data
: Neuroreport. 2018 May 2 ;29(7):564-569. PMID:
29481523
Article Published Date
: May 01, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Persimmon
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Flavonoids may act as a prenatal preventive against increased interleukin-6 mediated maternal immune activiation associated with abnormal social interactions in adult offspring.
Dec 10, 2009
Click here to read the entire abstract
Pubmed Data
: J Neuroimmunol. 2009 Dec 10;217(1-2):20-7. Epub 2009 Sep 18. PMID:
19766327
Article Published Date
: Dec 10, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Diosmin
,
Flavonoids
,
Luteolin
Diseases
:
Autism
,
Prenatal Nutrition: Health of the Offspring
Pharmacological Actions
:
Interleukin-6 Downregulation
[+]
Flavopiridol and paclitaxel exerted synergistic cytotoxic activities against SKOV3 cells in vitro and significantly suppress the tumor growth of mice bearing SKOV3 cells.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: Arch Gynecol Obstet. 2015 Jan ;291(1):143-50. Epub 2014 Aug 14. PMID:
25118834
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Ovarian Cancer
Pharmacological Actions
:
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
Additional Keywords
:
Chemothapeutic Synergy: Paclitaxel
[+]
French maritime pine tree bark extract improves sperm quality and function.
Oct 01, 2002
Click here to read the entire abstract
Pubmed Data
: J Reprod Med. 2002 Oct;47(10):821-4. PMID:
12418064
Article Published Date
: Oct 01, 2002
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Pycnogenol (Pine Bark)
Diseases
:
Infertility: Male
,
Sperm Quality: Low
Pharmacological Actions
:
Antioxidants
[+]
Galangin, a compound found within Alpinia galanga, acts as a chemosensitizer in drug-resistant leukemia cells.
Jul 08, 2008
Click here to read the entire abstract
Pubmed Data
: Cancer Lett. 2008 Jul 8;265(2):289-97. Epub 2008 Apr 18. PMID:
18374481
Article Published Date
: Jul 08, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Alpinia galanga
,
Flavonoids
Diseases
:
Cancers: Drug Resistant
,
Leukemia: Acute myelogenous leukemia (AML)
,
Leukemia: Chronic myelogenous leukemia (CML)
Pharmacological Actions
:
Apoptotic
,
Cell cycle arrest
,
Chemosensitizer
[+]
Ginkgo biloba extract relieves cerebral vasospasm and cerebral ischemic damage by reversing the pathological alteration of nitric oxide.
Jan 01, 2000
Click here to read the entire abstract
Pubmed Data
: Clin Hemorheol Microcirc. 2000;23(2-4):139-44. PMID:
11321433
Article Published Date
: Jan 01, 2000
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Ginkgo biloba
Diseases
:
Cerebral Ischemia
,
Cerebral Vasospasm
Additional Keywords
:
Plant Extracts
[+]
Grape seed extract has bactericidal effects on MRSA.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: J Toxicol Sci. 2010;35(3):357-64. PMID:
20519844
Article Published Date
: Jan 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Grape Seed Extract
,
Polyphenols
Diseases
:
MRSA
Pharmacological Actions
:
Anti-Bacterial Agents
,
Antioxidants
[+]
Grape seed extract has inhibiting effect on the accumulation of age-related oxidative DNA damages in the central nervous system of rats.
Feb 15, 2006
Click here to read the entire abstract
Pubmed Data
: Brain Res Bull. 2006 Feb 15;68(6):469-73. Epub 2005 Nov 2. PMID:
16459205
Article Published Date
: Feb 15, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Aging: Brain
,
DNA damage
,
Neurodegenerative Diseases
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
Additional Keywords
:
Plant Extracts
,
Proanthocyanidins
[+]
Grape seed polyphenols and curcumin reduce genomic instability events in a transgenic mouse model for Alzheimer's disease.
Feb 10, 2009
Click here to read the entire abstract
Pubmed Data
: Mutat Res. 2009 Feb 10;661(1-2):25-34. Epub 2008 Nov 6. PMID:
19027755
Article Published Date
: Feb 10, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Flavonoids
,
Grapefruit Seed Extract
,
Polyphenols
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Genoprotective
,
Neuroprotective Agents
Additional Keywords
:
Plant Extracts
[+]
Green tea has a growth inhibitory and antimetastatic effect on metastasis-specific mouse mammary cancer.
Mar 01, 2005
Click here to read the entire abstract
Pubmed Data
: Clin Cancer Res. 2005 Mar 1;11(5):1918-27. PMID:
15756018
Article Published Date
: Mar 01, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Green Tea
,
Polyphenols
Diseases
:
Breast Cancer: Lung Metastasis
,
Breast Cancer: Metastatic
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
[+]
Green tea has radioprotective properties against gamma-radiation exposure in mice.
Oct 01, 2008
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2008 Oct;22(10):1380-3. PMID:
18570224
Article Published Date
: Oct 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Green Tea
,
Polyphenols
,
Tea
Diseases
:
Radiation Induced Illness
Pharmacological Actions
:
Radioprotective
[+]
Green tea polyphenol and EGCG induce programmed cell death and inhibit invasion in human breast cancer cells.
Dec 01, 2007
Click here to read the entire abstract
Pubmed Data
: Cancer Biol Ther. 2007 Dec;6(12):1938-43. Epub 2007 Sep 1. PMID:
18059161
Article Published Date
: Dec 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Catechin
,
Flavonoids
,
Polyphenols
Diseases
:
Breast Cancer
,
Breast Cancer: Metastatic
Pharmacological Actions
:
Apoptotic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
[+]
Green tea polyphenol is able to attenuate alcoholic liver damage.
May 01, 2006
Click here to read the entire abstract
Pubmed Data
: Hepatobiliary Pancreat Dis Int. 2006 May;5(2):268-72. PMID:
16698589
Article Published Date
: May 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Green Tea
,
Polyphenols
Diseases
:
Alcoholic Liver Disease
Pharmacological Actions
:
Hepatoprotective
[+]
Green tea polyphenols (e.g. EGCG) have radioprotective properties.
May 01, 2010
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhong Yao Za Zhi. 2010 May;35(10):1328-31. PMID:
20707208
Article Published Date
: May 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Catechin
,
Flavonoids
,
Green Tea
,
Polyphenols
Diseases
:
Radiation Induced Illness
Pharmacological Actions
:
Radioprotective
Additional Keywords
:
Plant Extracts
[+]
Green tea polyphenols and its constituent EGCG inhibits proliferation of human breast cancer cells in vitro and in vivo.
Jan 08, 2007
Click here to read the entire abstract
Pubmed Data
: Cancer Lett. 2007 Jan 8;245(1-2):232-41. Epub 2006 Mar 6. PMID:
16519995
Article Published Date
: Jan 08, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Catechin
,
Flavonoids
,
Green Tea
,
Polyphenols
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
[+]
Green tea polyphenols mitigate deterioration of bone microarchitecture in middle-aged female rats.
Apr 01, 2009
Click here to read the entire abstract
Pubmed Data
: Bone. 2009 Apr;44(4):684-90. Epub 2008 Dec 11. PMID:
19118658
Article Published Date
: Apr 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
,
Tea
Diseases
:
Osteoporosis
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Bone Quality
[+]
Green tea prevents and reverses fasting-induced intestinal mucosal damage.
Jun 01, 2003
Click here to read the entire abstract
Pubmed Data
: Nutrition. 2003 Jun;19(6):536-40. PMID:
12781855
Article Published Date
: Jun 01, 2003
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
,
Vitamin E
Diseases
:
Intestinal Diseases
Therapeutic Actions
:
Fasting/Caloric Restriction
Pharmacological Actions
:
Antioxidants
[+]
Herbacetin ameliorates high percent dietary fat induced insulin resistance and lipid accumulation.
May 24, 2018
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2018 May 25 ;288:49-56. Epub 2018 Apr 11. PMID:
29653099
Article Published Date
: May 24, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Flaxseed
Diseases
:
High Fat Diet
,
Insulin Resistance
,
Obesity
Pharmacological Actions
:
Hypoglycemic Agents
,
Hypolipidemic
[+]
Herbacetin has potential for use as a therapeutic agent in disorders associated with bone loss.
Apr 14, 2016
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2016 Apr 15 ;777:17-25. Epub 2016 Feb 26. PMID:
26923730
Article Published Date
: Apr 14, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
,
Flaxseed
Diseases
:
Bone Diseases
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Herbacetin suppresses cutaneous squamous cell carcinoma and melanoma cell growth.
Jan 25, 2017
Click here to read the entire abstract
Pubmed Data
: Carcinogenesis. 2017 10 26 ;38(11):1136-1146. PMID:
29029040
Article Published Date
: Jan 25, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
,
Flaxseed
Diseases
:
Melanoma
,
Skin Cancer
,
Squamous cell carcinoma
Pharmacological Actions
:
Antiproliferative
,
NF-kappaB Inhibitor
,
Photoprotective
[+]
Hesperetin attenuates testicular damage in diabetic rats.
Sep 30, 2018
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2018 Oct 1 ;210:132-139. Epub 2018 Sep 1. PMID:
30179627
Article Published Date
: Sep 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Hesperidin
Diseases
:
Diabetic Complications
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
[+]
Hesperidin attenuates depression-related symptoms in mice with mild traumatic brain injury.
Nov 14, 2018
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2018 Nov 15 ;213:198-205. Epub 2018 Oct 21. PMID:
30352242
Article Published Date
: Nov 14, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Hesperidin
Diseases
:
Brain Inflammation
,
Brain Injury: Traumatic
,
Depression
,
Oxidative Stress
Pharmacological Actions
:
Antidepressive Agents
,
Brain-derived neurotrophic factor modulator
,
Interleukin-1 beta downregulation
,
Malondialdehyde Down-regulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Icariin has a neuroprotective effect on memory impairment and neurochemical deficits in age-acceleration prone mice.
Jun 02, 2010
Click here to read the entire abstract
Pubmed Data
: Brain Res. 2010 Jun 2;1334:73-83. Epub 2010 Apr 7. PMID:
20380820
Article Published Date
: Jun 02, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Icariin
Diseases
:
Aging
,
Aging: Brain
,
Cognitive Decline/Dysfunction
,
Memory Disorders
,
Oxidative Stress
Pharmacological Actions
:
Neuroprotective Agents
[+]
Icariin protects against against learning and memory deficits induced by aluminium in rats.
Aug 01, 2007
Click here to read the entire abstract
Pubmed Data
: Clin Exp Pharmacol Physiol. 2007 Aug;34(8):792-5. PMID:
17600559
Article Published Date
: Aug 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Icariin
Diseases
:
Aluminum Toxicity
,
Learning disorders
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
[+]
Immunomodulation by pycnogenol in retrovirus-infected or ethanol-fed mice.
Dec 31, 1995
Click here to read the entire abstract
Pubmed Data
: Life Sci. 1996 ;58(5):PL 87-96. PMID:
8594302
Article Published Date
: Dec 31, 1995
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Alcohol Toxicity
,
Mouse Endogenous Retroviruses
[+]
Intake of fisetin during pregnancy in rats ameliorated in utero mercury exposure induced neurotoxicity outcomes.
May 31, 2017
Click here to read the entire abstract
Pubmed Data
: Biol Trace Elem Res. 2017 Jun ;177(2):297-315. Epub 2016 Nov 4. PMID:
27815688
Article Published Date
: May 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Fisetin
,
Flavonoids
Diseases
:
Mercury Poisoning
,
Neurodegenerative Diseases
,
Oxidative Stress
,
Prenatal Chemical Exposures
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Fisetin
,
Flavonoids
,
Mercury Poisoning
,
Methylmercury
,
Neurodegenerative diseases
,
oxidative stress
,
Prenatal Chemical Exposures
Problem Substances
:
Mercury
[+]
Isoliquiritigenin (ISL), a flavonoid chalcone that is present in licorice, shallot, and bean sprouts, has antitumorigenic activities in prostate tumor cells.
Feb 01, 2009
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2009 Feb;12(1):8-14. PMID:
19298190
Article Published Date
: Feb 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Beans: All
,
Flavonoids
,
Isoliquiritigenin
,
Licorice
,
Shallot
,
Sprouts
Diseases
:
Prostate Cancer
Pharmacological Actions
:
Cell cycle arrest
,
Enzyme Inhibitors
Additional Keywords
:
Plant Extracts
[+]
Licorice ethanolic extract may be effective in preventing and ameliorating diabetes, ameliorating abdominal obesity and preventing hypertension (three facets of metabolic syndrome).
Nov 01, 2003
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2003 Nov;133(11):3369-77. PMID:
14608046
Article Published Date
: Nov 01, 2003
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Licorice
Diseases
:
Abdominal Obesity (Midsection Fat)
,
Diabetes Mellitus: Type 2
,
Hypertension
,
Metabolic Syndrome X
Additional Keywords
:
Plant Extracts
[+]
Licorice flavonoid oil exhibits anti-obesity action in diet-induced obesity in rats.
Nov 01, 2008
Click here to read the entire abstract
Pubmed Data
: J Cardiovasc Pharmacol. 2008 Nov;52(5):452-458. PMID:
19060415
Article Published Date
: Nov 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Obesity
Additional Keywords
:
Anti-Obesity Agents
[+]
Licorice has hypocholesterolaemic and antioxidant effects.
Nov 01, 2006
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2006 Nov;50(11):1080-6. PMID:
17054099
Article Published Date
: Nov 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Licorice
,
Polyphenols
Diseases
:
Hypercholesterolemia
Pharmacological Actions
:
Anticholesteremic Agents
,
Antioxidants
[+]
Longan flower water extract has antiobesity and hypolipidemic effects.
Feb 10, 2010
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2010 Feb 10;58(3):2020-7. PMID:
20088600
Article Published Date
: Feb 10, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Flowers
,
Longan
,
Polyphenols
Diseases
:
Hyperlipidemia
,
Obesity
Additional Keywords
:
Plant Extracts
[+]
Lotus flower leaf has anti-obesity effects in mice.
Jun 09, 2010
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2010 Jun 9;58(11):7075-81. PMID:
20481471
Article Published Date
: Jun 09, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Lotus
Diseases
:
Obesity
Additional Keywords
:
Anti-Obesity Agents
,
Plant Extracts
[+]
Lotus stamen has aldose reductase inhibitory which may have value in preventing diabetes-associated eye damage.
Oct 01, 2006
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2006 Oct;20(10):825-30. PMID:
16881021
Article Published Date
: Oct 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Lotus
Diseases
:
Diabetes: Cataract
Pharmacological Actions
:
Aldose reductase inhibitor
Additional Keywords
:
Plant Extracts
[+]
Low doses of Moringa revealed excellent antidiabetic activity and almost restored the diabetic rats to the normal healthy state.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Res Int. 2015 ;2015:381040. Epub 2015 Jan 5. PMID:
25629046
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Moringa oleifera
Diseases
:
Diabetes Mellitus: Type 1
,
Diabetic Nephropathy
Pharmacological Actions
:
Antioxidants
,
Interleukin-6 Downregulation
Additional Keywords
:
Plant Extracts
[+]
Lychee fruit extract suppressed the expression of inflammatory genes, resulting in anti-inflammatory effects through its inhibition of NF-κB activation and mRNA interactions.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2014 ;9(4):e93818. Epub 2014 Apr 4. PMID:
24705335
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Flavan-3-ols
,
Flavonoids
,
Lychee
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
M. officinalis demonstrated dose dependant in-vitro iron chelating ability.
Nov 30, 2016
Click here to read the entire abstract
Pubmed Data
: Drug Res (Stuttg). 2016 Dec ;66(12):618-627. Epub 2016 Sep 14. PMID:
27626608
Article Published Date
: Nov 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Yellow Sweet Clover (Melilotus officinalis)
Diseases
:
Iron Overload
Pharmacological Actions
:
Iron Chelating Agents
Additional Keywords
:
Plant Extracts
[+]
Mango leaves hae antioxidant and antiulcerogenic action.
Jan 01, 2009
Click here to read the entire abstract
Pubmed Data
: Molecules. 2009;14(3):1098-110. Epub 2009 Mar 10. PMID:
19305363
Article Published Date
: Jan 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Mangiferin
,
Mango
,
Polyphenols
Diseases
:
Gastric Ulcer
Pharmacological Actions
:
Anti-Ulcer Agents
Additional Keywords
:
Xanthones
[+]
Melatonin and pycnogenol have a therapeutic role in the treatment fo endothelial dysfunction.
Aug 01, 2003
Click here to read the entire abstract
Pubmed Data
: Int J Mol Med. 2003 Aug;12(2):269-73. PMID:
20421515
Article Published Date
: Aug 01, 2003
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Melatonin
Diseases
:
Endothelial Dysfunction
,
Hypertension
Pharmacological Actions
:
Antihypertensive Agents
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
[+]
Milk thistle sprouts have significant antioxidant value which increases with light exposure.
Sep 05, 2005
Click here to read the entire abstract
Pubmed Data
: Br J Cancer. 2005 Sep 5;93(5):590-6. PMID:
17852500
Article Published Date
: Sep 05, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Milk Thistle
,
Polyphenols
,
Sprouts
Diseases
:
Oxidative Stress
Therapeutic Actions
:
Light Therapy
Pharmacological Actions
:
Antioxidants
[+]
Moderate consumption of Cabernet Sauvignon attenuates Abeta neuropathology in a mouse model of Alzheimer's disease.
Nov 01, 2006
Click here to read the entire abstract
Pubmed Data
: FASEB J. 2006 Nov;20(13):2313-20. PMID:
17077308
Article Published Date
: Nov 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
,
Wine
Diseases
:
Alzheimer's Disease
[+]
Morus alba leaves flavonoid extract and Morus alba leaves powder treatment could be useful agents in diabetes improvement.
May 29, 2016
Click here to read the entire abstract
Pubmed Data
: Cell Mol Biol (Noisy-le-grand). 2016 May 30 ;62(6):112-8. Epub 2016 May 30. PMID:
27262814
Article Published Date
: May 29, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
White Mulberry
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hypoglycemic Agents
Additional Keywords
:
Anti-Inflammatory Agents
,
Diabetes mellitus: Type 2
,
Flavonoids
,
Hypoglycemic Agents
,
Phytotherapy
,
Plant Extracts
,
White Mulberry
[+]
Muskmelon, watermelon and mango fruit may have an ameliorative effect on atherogenic diet induced dyslipidemia, hypothyroidism and hyperglycemia in rats.
Jan 01, 2008
Click here to read the entire abstract
Pubmed Data
: Biofactors. 2008;33(1):13-24. PMID:
19276533
Article Published Date
: Jan 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Mango
,
Muskmelon
,
Polyphenols
,
Vitamin C
,
Watermelon
Diseases
:
Arteriosclerosis
,
Dyslipidemias
,
Hyperglycemia
,
Hypothyroidism
,
Oxidative Stress
Pharmacological Actions
:
Hypoglycemic Agents
Additional Keywords
:
Plant Extracts
[+]
Nobiletin supplementation inhibited activation of apoptotic pathways and DNA damage.
May 18, 2015
Click here to read the entire abstract
Pubmed Data
: Exp Toxicol Pathol. 2015 May 19. Epub 2015 May 19. PMID:
26002685
Article Published Date
: May 18, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Nobiletin
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
DNA damage
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Chemoprotective Agents
,
Renoprotective
[+]
Nutritional antioxidants such as green tea polyphenols and tetrahydrocurcumin may beneficially modify the life span of animals.
Oct 01, 2007
Click here to read the entire abstract
Pubmed Data
: Biogerontology. 2007 Oct;8(5):567-73. Epub 2007 May 22. PMID:
17516143
Article Published Date
: Oct 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Green Tea
,
Polyphenols
,
Tetrahydrocurcumin
Diseases
:
Aging
Additional Keywords
:
Plant Extracts
[+]
Olive leaf contains phenolics with radioprotective properties.
Jan 01, 1994
Click here to read the entire abstract
Pubmed Data
: J Hepatol. 1994 Jan;20(1):41-6. PMID:
12495584
Article Published Date
: Jan 01, 1994
Study Type
: Animal Study
Additional Links
Substances
:
Diosmin
,
Flavonoids
,
Olive leaf extract
,
Rutin
Diseases
:
Radiation Induced Illness
Pharmacological Actions
:
Antioxidants
,
Radioprotective
Additional Keywords
:
Plant Extracts
[+]
Onion flesh and onion peel enhance antioxidant status in aged rats.
Feb 01, 2007
Click here to read the entire abstract
Pubmed Data
: J Nutr Sci Vitaminol (Tokyo). 2007 Feb;53(1):21-9. PMID:
17484375
Article Published Date
: Feb 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Onion
,
Polyphenols
,
Quercetin
Diseases
:
Aging
,
DNA damage
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Plant Extracts
[+]
Oral administration of apigenin significantly reduced elevated levels of SASP and IκBζ mRNA in the kidneys of aged rats.
Jun 16, 2015
Click here to read the entire abstract
Pubmed Data
: Biochem Pharmacol. 2015 Jun 17. Epub 2015 Jun 17. PMID:
26093063
Article Published Date
: Jun 16, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Apigenin
,
Flavonoids
,
Kaempferol
Diseases
:
Cardiovascular Diseases
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
MicroRNA modulator
,
NF-kappaB Inhibitor
Additional Keywords
:
Senescence-associated Secretory Phenotype
[+]
Orange peel flavonoids inhibit experimental adjuvant-induced rat arthritis.
May 01, 2010
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhong Yao Za Zhi. 2010 May;35(10):1298-301. PMID:
20707201
Article Published Date
: May 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Orange
Diseases
:
Arthritis
,
Inflammation
,
Osteoarthritis
Pharmacological Actions
:
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Adjuvant-Induced Injury
,
Plant Extracts
[+]
Peppermint protects against radiation-induced testicular damage.
Apr 01, 2009
Click here to read the entire abstract
Pubmed Data
: Basic Clin Pharmacol Toxicol. 2009 Apr;104(4):329-34. PMID:
19320637
Article Published Date
: Apr 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Peppermint
Diseases
:
Lipid Peroxidation
,
Radiation Induced Illness
Pharmacological Actions
:
Antioxidants
,
Radioprotective
Additional Keywords
:
Plant Extracts
[+]
Phyllanthus amarus has radioprotective properties.
Jan 01, 2009
Click here to read the entire abstract
Pubmed Data
: Ann Oncol. 2009 Jan;20(1):160-5. Epub 2008 Jul 31. PMID:
19461166
Article Published Date
: Jan 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Phyllanthus amarus
,
Polyphenols
Diseases
:
Radiation Induced Illness
Pharmacological Actions
:
Radioprotective
Additional Keywords
:
Plant Extracts
[+]
Pine need extract is anti-inflammatory and has a protective effect on cholesteorl oxidation.
Jan 01, 2008
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2008 Jan;46(1):175-85. Epub 2007 Jul 28. PMID:
17804140
Article Published Date
: Jan 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Pine Needle
,
Polyphenols
Diseases
:
Cholesterol: Oxidation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Enzyme Inhibitors
[+]
Plantain extract has neutralizing properties on snake venom induced toxicity.
Apr 08, 2005
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2005 Apr 8;98(1-2):21-9. PMID:
15763360
Article Published Date
: Apr 08, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Plantain
,
Polyphenols
,
Tannic Acid
Diseases
:
Snake Bite: Venom Toxicity
Additional Keywords
:
Plant Extracts
[+]
Polymerized catechin compounds in apple polyphenol extracts inhibit the biological and enzymatic activities of cholera toxin.
Dec 31, 2001
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Microbiol Immunol. 2002 ;46(4):249-55. PMID:
12061627
Article Published Date
: Dec 31, 2001
Study Type
: Animal Study
Additional Links
Substances
:
Apple Polyphenols
,
Catechin
,
Flavonoids
Diseases
:
Cholera
Pharmacological Actions
:
Antidiarrheals
,
Antimicrobial
,
Enzyme Inhibitors
Additional Keywords
:
Dose Response
,
Plant Extracts
[+]
Pomegranate juice decreases amyloid load and improves behavior in a mouse model of Alzheimer's disease.
Nov 30, 2006
Click here to read the entire abstract
Pubmed Data
: Neurobiol Dis. 2006 Dec ;24(3):506-15. Epub 2006 Sep 28. PMID:
17010630
Article Published Date
: Nov 30, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
,
Pomegranate
Pharmacological Actions
:
Antioxidants
[+]
Pretreatment with black tea polyphenols positively modulates xenobiotic-metabolizing enzymes in an experimental oral carcinogenesis model.
Jan 01, 2008
Click here to read the entire abstract
Pubmed Data
: Oncol Res. 2008;17(2):75-85. PMID:
18543609
Article Published Date
: Jan 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Black Tea
,
Flavonoids
Diseases
:
DNA damage
,
Oral Cancer
Pharmacological Actions
:
Chemopreventive
,
Phase II Detoxification Enzyme Inducer
[+]
Propolis has radioprotective properties.
Sep 15, 2006
Click here to read the entire abstract
Pubmed Data
: Toxicol Appl Pharmacol. 2006 Sep 15;215(3):295-305. Epub 2006 May 18. PMID:
17473440
Article Published Date
: Sep 15, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Bee Propolis
,
Flavonoids
,
Polyphenols
Diseases
:
Radiation Induced Illness
Pharmacological Actions
:
Radioprotective
[+]
Protection of the flavonoid fraction from Rosa laevigata Michx fruit against carbon tetrachloride-induced acute liver injury in mice.
Apr 30, 2013
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2013 May ;55:60-9. Epub 2012 Dec 29. PMID:
23279844
Article Published Date
: Apr 30, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Rose
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Protective effect of the total flavonoids from Rosa laevigata Michx fruit on renal ischemia-reperfusion injury.
Jul 20, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2016 Jul 21 ;21(7). Epub 2016 Jul 21. PMID:
27455216
Article Published Date
: Jul 20, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Rose
Diseases
:
Inflammation
,
Ischemia
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
Pterocarpus marsupium exhibits antihyperlipidemic activities.
Feb 01, 2006
Click here to read the entire abstract
Pubmed Data
: Eur J Cancer. 2006 Feb;42(3):415-21. Epub 2006 Jan 4. PMID:
8377021
Article Published Date
: Feb 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Pterocarpus marsupium
Diseases
:
Cholesterol: LDL/HDL ratio
,
Hyperlipidemia
Pharmacological Actions
:
Anticholesteremic Agents
Additional Keywords
:
Plant Extracts
[+]
Pycnogenol accelerates wound healing and reduces scar formation.
Jul 01, 2004
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2004 Jul;18(7):579-81. PMID:
15305320
Article Published Date
: Jul 01, 2004
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Pycnogenol (Pine Bark)
Diseases
:
Scars
,
Wound Healing
Additional Keywords
:
Plant Extracts
[+]
Pycnogenol ameliorate experimental inflammatory bowel diseases.
Dec 01, 2004
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2004 Dec;18(12):1027-8. PMID:
15742344
Article Published Date
: Dec 01, 2004
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Pycnogenol (Pine Bark)
Diseases
:
Inflammatory Bowel Diseases
Additional Keywords
:
Plant Extracts
[+]
R. damascena can reverse behavioural deficits caused by amyloid-A-β in rats.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Adv Biomed Res. 2015 ;4:131. Epub 2015 Jul 27. PMID:
26322279
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Rose
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Red wine polyphenols prevent hypertension and endothelial dysfunction in rats.
Sep 01, 2006
Click here to read the entire abstract
Pubmed Data
: Cardiovasc Res. 2006 Sep 1;71(4):794-802. Epub 2006 May 26. PMID:
16822492
Article Published Date
: Sep 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
,
Red Wine Extract
Diseases
:
Endothelial Dysfunction
,
Hypertension
Pharmacological Actions
:
Cardioprotective
,
Vasodilator Agents
[+]
Resveratrol exhibits anti-inflammatory properties related to inhibition of tumour necrosis factor-alpha (TNF-alpha) pre-mRNA splicing.
Jun 01, 2004
Click here to read the entire abstract
Pubmed Data
: Fitoterapia. 2004 Jun;75(3-4):375-7. PMID:
19945165
Article Published Date
: Jun 01, 2004
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
,
Resveratrol
,
Stilbenes
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Rhus verniciflua stokes (Sumac) contains compounds which exhibit anti-inflammatory and anti-angiogenic activity in rheumatoid arthritis synovial cells and in vivo modles.
Mar 01, 2009
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2009 Mar;9(3):268-76. Epub 2008 Dec 25. PMID:
19111632
Article Published Date
: Mar 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Sumac
Diseases
:
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Angiogenic
,
Anti-Inflammatory Agents
,
Enzyme Inhibitors
[+]
Rosa laevigata fruit could be used in the treatment of NAFLD.
Nov 30, 2013
Click here to read the entire abstract
Pubmed Data
: Food Chem. 2013 Dec 1 ;141(3):2108-16. Epub 2013 May 16. PMID:
23870935
Article Published Date
: Nov 30, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Rose
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
,
Hypolipidemic
Additional Keywords
:
Plant Extracts
[+]
Rosa rugosa flavonoids significantly inhibited myocardial ischemia reperfusion injury.
Sep 30, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Microcirculation. 2017 Oct ;24(7). PMID:
28597598
Article Published Date
: Sep 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Rose
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Cardioprotective
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
Rutin inhibits nitric oxide and tumor necrosis factor-alpha production in lipopolysaccharide and concanavalin-a stimulated macrophages.
Jan 01, 2007
Click here to read the entire abstract
Pubmed Data
: Drug Metabol Drug Interact. 2007;22(4):263-78. PMID:
18447002
Article Published Date
: Jan 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Rutin
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Nitric Oxide Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Sea buckthorn flavonoids can enhance heart function, protect vascular endothelial cells, and fight against myocardial ischemia.
Mar 31, 2017
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhong Yao Za Zhi. 2017 Apr ;42(7):1238-1244. PMID:
29052380
Article Published Date
: Mar 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Sea buckthorn
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Cardioprotective
[+]
Serum C-reactive protein concentrations are inversely associated with dietary flavonoid intake in U.S. adults.
Apr 01, 2008
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2008 Apr;138(4):753-60. PMID:
18356331
Article Published Date
: Apr 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
C-Reactive Protein
Additional Keywords
:
Risk Reduction
[+]
Silymarin has radioprotective properties.
May 01, 2010
Click here to read the entire abstract
Pubmed Data
: Z Naturforsch C. 2010 May-Jun;65(5-6):337-46. PMID:
20653235
Article Published Date
: May 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Milk Thistle
Diseases
:
Radiation Induced Illness
Pharmacological Actions
:
Antioxidants
,
NF-kappaB Inhibitor
,
Radioprotective
[+]
Soybean and green tea polyphenols improve immune function and redox status in very old ovariectomized mice.
Dec 01, 2010
Click here to read the entire abstract
Pubmed Data
: Rejuvenation Res. 2010 Dec;13(6):665-74. Epub 2010 Sep 6. PMID:
20818935
Article Published Date
: Dec 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Green Tea
,
Polyphenols
,
Soy
,
Tea
Diseases
:
Aging
,
Aging: Immunosenecence
,
Lipid Peroxidation
,
Ovariectomy Associated Adverse Changes
Pharmacological Actions
:
Antioxidants
,
Interleukin-10 downregulation
,
Interleukin-6 Downregulation
[+]
Supplementation with fenugreek seeds is significantly effective in protecting the liver and kidneys from carbon tetrachloride toxicity.
Mar 31, 2017
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2017 Apr ;88:19-26. Epub 2017 Jan 13. PMID:
28092841
Article Published Date
: Mar 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Fenugreek
,
Flavonoids
Diseases
:
Chemically-Induced Liver Damage
,
Kidney Damage: Chemically-Induced
,
Lipid Peroxidation
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Renoprotective
Additional Keywords
:
Plant Extracts
[+]
T. americana var. mexicana significantly prevented severity of PTZ-induced seizures and attenuated oxidative stress levels.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2014 ;2014:329172. Epub 2014 Aug 13. PMID:
25197430
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Linden (Tilia)
,
Quercetin
,
Rutin
Diseases
:
Oxidative Stress
,
Seizures
Pharmacological Actions
:
Anticonvulsants
,
Antioxidants
Additional Keywords
:
Plant Extracts
[+]
Tartary buckwheat flavonoids ameliorate high fructose-induced insulin resistance and oxidative stress.
Jul 16, 2017
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2017 Jul 17. Epub 2017 Jul 17. PMID:
28714504
Article Published Date
: Jul 16, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Buckwheat
,
Flavonoids
Diseases
:
High Fructose Diet
,
Insulin Resistance
Pharmacological Actions
:
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Nrf2 activation
Additional Keywords
:
Antioxidants
,
Buckwheat
,
Flavonoids
,
High Fructose Diet
,
Insulin Resistance
[+]
The aqueous extracts of Passiflora alata and Passiflora edulis reduce anxiety-related behaviors without affecting memory process in rats.
May 31, 2008
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2008 Jun ;11(2):282-8. PMID:
18598170
Article Published Date
: May 31, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Passion Flower
Diseases
:
Anxiety
Pharmacological Actions
:
Anti-Anxiety Agents
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
The consumption of dietary polyphenols (wine) with foods (turkey meat) containing oxidized fats reduces potentially harmful oxidative stress.
Jul 09, 2008
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2008 Jul 9;56(13):5002-7. Epub 2008 Jun 10. PMID:
18540628
Article Published Date
: Jul 09, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
,
Wine
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Antioxidants
[+]
The flavonaids of propolis have inhibitory effect on apoptosis of myocardial cells of chronic heart failure induced by adriamycin in rats.
Apr 30, 2015
Click here to read the entire abstract
Pubmed Data
: Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2015 May ;31(3):201-6. PMID:
26387177
Article Published Date
: Apr 30, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Propolis: Bee
Diseases
:
Heart Failure
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Gene Expression Regulation
[+]
The flavonoid baicalin found in Chinese skullcap protects against cerebrovascular dysfunction and brain inflammation in experimental heatstroke.
Mar 01, 2007
Click here to read the entire abstract
Pubmed Data
: Neuropharmacology. 2007 Mar;52(3):1024-33. Epub 2007 Jan 3. PMID:
17204294
Article Published Date
: Mar 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Catechols
,
Chinese Skullcap
,
Flavonoids
Diseases
:
Brain Inflammation
,
Heat Stroke
[+]
The flavonoid extracted from citrus known as luteolin reduces Alzheimer's disease beta-amyloid plaque production in mice.
Mar 01, 2009
Click here to read the entire abstract
Pubmed Data
: J Cell Mol Med. 2009 Mar;13(3):574-88. Epub 2008 Apr 9. PMID:
18410522
Article Published Date
: Mar 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Luteolin
Diseases
:
Alzheimer's Disease
[+]
The flavonoid fraction of broccoli inhibits selenite-induced cataract formation in an animal model.
Feb 01, 2010
Click here to read the entire abstract
Pubmed Data
: Curr Eye Res. 2010 Feb;35(2):99-107. PMID:
20136419
Article Published Date
: Feb 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Broccoli
,
Flavonoids
Diseases
:
Cataract
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Plant Extracts
,
Sodium Selenite
[+]
The flavonoid glycoside astragalin may be a new therapeutic agent for the management of menopausal symptoms.
May 20, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2016 May 21 ;21(5). Epub 2016 May 21. PMID:
27213327
Article Published Date
: May 20, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
White Mulberry
Diseases
:
Menopausal Syndrome
Pharmacological Actions
:
Anti-Apoptotic
Additional Keywords
:
Anti-Apoptotic
,
Flavonoids
,
Menopausal Syndrome
,
White Mulberry
[+]
The flavonoids diosmin and hesperidin inhibit experimentally-induced oral carcinogenesis in rats.
Jan 15, 1997
Click here to read the entire abstract
Pubmed Data
: Cancer Res. 1997 Jan 15;57(2):246-52. PMID:
9000563
Article Published Date
: Jan 15, 1997
Study Type
: Animal Study
Additional Links
Substances
:
Diosmin
,
Flavonoids
,
Hesperidin
Diseases
:
Oral Cancer
[+]
The grapefruit flavanone naringin protects against the radiation-induced genomic instability in the mice bone marrow.
Aug 26, 2002
Click here to read the entire abstract
Pubmed Data
: Mutat Res. 2002 Aug 26;519(1-2):37-48. PMID:
12160890
Article Published Date
: Aug 26, 2002
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Grapefruit
,
Naringenin
Diseases
:
DNA damage
,
Radiation Induced Illness
,
Radiation Induced Illness: Bone Marrow
Pharmacological Actions
:
Antioxidants
,
Radioprotective
[+]
The phytochemical synergy among the constituents of Graviola leaf extracts protected against prostate cancer, and enhanced the bioavailability of rutin 7-fold and quercetin 3-fold.
Apr 10, 2015
Click here to read the entire abstract
Pubmed Data
: Carcinogenesis. 2015 Apr 11. Epub 2015 Apr 11. PMID:
25863125
Article Published Date
: Apr 10, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
,
Graviola
Diseases
:
Prostate Cancer
Pharmacological Actions
:
Antiproliferative
,
Chemopreventive
,
Chemotherapeutic
Additional Keywords
:
Bioavailability
,
Natural Substance Synergy
,
Plant Leaves
[+]
The plant polyphenols genistein and resveratrol preserve ovarian follicular function in aging rats.
Aug 01, 2010
Click here to read the entire abstract
Pubmed Data
: Biochem Cell Biol. 2010 Aug;88(4):737-45. PMID:
20651847
Article Published Date
: Aug 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Genistein
,
Polyphenols
,
Resveratrol
Diseases
:
Aging
,
Infertility: Aging Associated
,
Infertility: Female
Additional Keywords
:
Plant Extracts
,
Stilbenes
[+]
Theaflavin and thearubigins based dietary interventions are helpful to alleviate the hypercholestrolemia and hyperglycemia.
Mar 26, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Lipids Health Dis. 2018 Mar 27 ;17(1):57. Epub 2018 Mar 27. PMID:
29592809
Article Published Date
: Mar 26, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Black Tea
,
Flavonoids
,
Polyphenols
Diseases
:
Hypercholesterolemia
,
Hyperlipidemia
Pharmacological Actions
:
Hypolipidemic
[+]
These findings confirmed the potent effects of total flavonoids from Rosa laevigata fruit against hepatic ischemia-reperfusion Injury
Jul 07, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2016 Jul 8 ;8(7). Epub 2016 Jul 8. PMID:
27399769
Article Published Date
: Jul 07, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Rose
Diseases
:
Liver Injury: Ischemia/reperfusion
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
These results confirm that myricetin exerts neuroprotective effect in experimental Parkinson's disease.
May 31, 2018
Click here to read the entire abstract
Pubmed Data
: Front Biosci (Elite Ed). 2018 Jun 1 ;10:481-494. Epub 2018 Jun 1. PMID:
29772521
Article Published Date
: May 31, 2018
Study Type
: Insect Study
Additional Links
Substances
:
Flavonoids
,
Myricetin
,
Seaweed: Brown
Diseases
:
Parkinson's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
This study provides evidence that morin may have anticancer effects against metastatic breast cancer.
Sep 30, 2014
Click here to read the entire abstract
Pubmed Data
: Int J Oncol. 2014 Oct ;45(4):1629-37. Epub 2014 Jul 4. PMID:
24993541
Article Published Date
: Sep 30, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Fig
,
Flavonoids
,
Mulberry
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
,
Cancer Metastasis
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Antiproliferative
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Plant Extracts
[+]
Topical pycnogenol protects against inflammation, immunosuppression and carcinogensis induced by UV radiation in mice.
Feb 01, 2004
Click here to read the entire abstract
Pubmed Data
: Photochem Photobiol. 2004 Feb;79(2):193-8. PMID:
15068032
Article Published Date
: Feb 01, 2004
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Pycnogenol (Pine Bark)
Diseases
:
Skin Cancer: Prevention
,
Sunburn
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticarcinogenic Agents
,
Chemopreventive
,
Immunomodulatory
[+]
Total flavonoids found in black mulberry possess anti-inflammatory and analgesic effects.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2016 ;11(4):e0153080. Epub 2016 Apr 5. PMID:
27046026
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Mulberry
Diseases
:
Inflammation
Pharmacological Actions
:
Analgesics
,
Anti-Inflammatory Agents
,
Antioxidants
,
Interferon Gamma Reducer
,
Interleukin-1 beta downregulation
,
Nitric Oxide Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Total flavonoids from Rosa laevigata fruit exhibited protective effect against lipopolysaccharide-induced liver injury.
Jun 07, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Foods. 2018 Jun 8 ;7(6). Epub 2018 Jun 8. PMID:
29890650
Article Published Date
: Jun 07, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Rose
Diseases
:
Chemically-Induced Liver Damage
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Hepatoprotective
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Nrf2 activation
[+]
Various foods and polyphenols inhibit activation of aryl hydrocarbon receptor induced by diesel exhaust particles.
Jan 01, 2007
Click here to read the entire abstract
Pubmed Data
: Environ Sci. 2007;14(3):149-56. PMID:
17622219
Article Published Date
: Jan 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Garlic
,
Ginkgo biloba
,
Onion
,
Polyphenols
Diseases
:
Diesel Exhaust Particle Toxicity
,
Petroleum Exposure And Toxicity
Additional Keywords
:
Plant Extracts
[+]
Walnut polyphenols prevent chemically-induced liver damage .
Jun 25, 2008
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2008 Jun 25;56(12):4444-9. Epub 2008 May 22. PMID:
18494495
Article Published Date
: Jun 25, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
,
Tannic Acid
,
Walnut
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Water spinach flavonoids could offer protection against arsenic toxicity by counteracting oxidative
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Transl Med. 2015 ;13(1):81. Epub 2015 Mar 5. PMID:
25890105
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Spinach
Diseases
:
Arsenic Poisoning
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Cytoprotective
[+]
Wild carrot oil fractions exhibited a unique chemical composition and possessed significant antioxidant activities as well as hepatoprotective effects against carbon tetrachloride induced hepatotoxicity.
Apr 08, 2015
Click here to read the entire abstract
Pubmed Data
: Pharm Biol. 2015 Apr 9:1-10. Epub 2015 Apr 9. PMID:
25856705
Article Published Date
: Apr 08, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Carrot
,
Flavonoids
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
A grape seed extract rich in procyanidins achieves direct and indirect (i.e. cell-mediated) protection of LDL against oxidation.
May 01, 2003
Click here to read the entire abstract
Pubmed Data
: Free Radic Res. 2003 May;37(5):573-84. PMID:
12797479
Article Published Date
: May 01, 2003
Study Type
: In Vitro Study
Additional Links
Substances
:
Flavonoids
,
Grape
,
Grape Seed Extract
,
Polyphenols
Diseases
:
Cholesterol: Oxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Plant Extracts
[+]
A guava leaf extract contains potential therapeutic agents, which regulate NF-κB activation, for the treatment of inflammatory conditions.
Oct 31, 2015
Click here to read the entire abstract
Pubmed Data
: Fish Shellfish Immunol. 2015 Nov ;47(1):85-92. Epub 2015 Aug 29. PMID:
26327113
Article Published Date
: Oct 31, 2015
Study Type
: In Vitro Study
Additional Links
Substances
:
Flavonoids
,
Guava
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-10 downregulation
,
Interleukin-1 beta downregulation
,
Postaglandin PGE2 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Dose Response
,
Plant Extracts
[+]
A lyophilized grape extract comparable to putative dietary doses induced important morphology changes, migration inhibition, downregulation of undifferentiated stem/stem-like cells markers and EMT.
Mar 31, 2015
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2015 Apr ;67(3):494-503. Epub 2015 Feb 23. PMID:
25705818
Article Published Date
: Mar 31, 2015
Study Type
: In Vitro Study
Additional Links
Substances
:
Anthocyanins
,
Flavonoids
,
Grape
,
Polyphenols
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antioxidants
,
Antiproliferative
,
Cell cycle arrest
,
E-cadherin down-regulation
,
Nrf2 activation
,
P21 Activation
,
Tumor Suppressor Protein p53 Upregulation
Additional Keywords
:
Cancer Stem Cells
,
Dietary Doses
,
Plant Extracts
[+]
A Mediterranean diet may protect against homocysteine-induced cardiovascular damage.
Sep 01, 2010
Click here to read the entire abstract
Pubmed Data
: Chemosphere. 2010 Sep;81(4):464-8. PMID:
17586618
Article Published Date
: Sep 01, 2010
Study Type
: Commentary
Additional Links
Substances
:
Flavonoids
,
Hydroxytyrosol
,
Polyphenols
,
Resveratrol
Diseases
:
High Homocysteine
Therapeutic Actions
:
Dietary Modification: Mediterranean Diet
Pharmacological Actions
:
Antioxidants
,
Proteasome Inhibitors
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
,
Vascular Cell Adhesion Molecule-1 Inhibitor
Additional Keywords
:
Stilbenes
[+]
A methanol extract of Nardostachys jatamansi possess significant antiproliferative potential.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2015 ;15:50. Epub 2015 Mar 10. PMID:
25886964
Article Published Date
: Dec 31, 2014
Study Type
: In Vitro Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
,
Spikenard
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
Pharmacological Actions
:
Antioxidants
,
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
A number of plant polyphenols have chemosensitizing and radiosensitizing activity.
Nov 01, 2005
Click here to read the entire abstract
Pubmed Data
: Antioxid Redox Signal. 2005 Nov-Dec;7(11-12):1630-47. PMID:
16356126
Article Published Date
: Nov 01, 2005
Study Type
: Review
Additional Links
Substances
:
Betulinic acid
,
Caffeic acid phenethyl ester
,
Curcumin
,
Emodin
,
Flavonoids
,
Genistein
,
Green Tea
,
Polyphenols
,
Resveratrol
,
Silymarin
,
Ursolic Acid
Diseases
:
Cancers: Drug Resistant
Pharmacological Actions
:
Chemosensitizer
,
Radiosensitizer
[+]
A phytochemical and pharmacological review of corn silk in healthcare.
Aug 12, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2012 Aug 13 ;17(8):9697-715. Epub 2012 Aug 13. PMID:
22890173
Article Published Date
: Aug 12, 2012
Study Type
: Review
Additional Links
Substances
:
Corn Silk
,
Flavonoids
Diseases
:
Depression
,
Fatigue
,
Hyperglycemia
Pharmacological Actions
:
Antidepressive Agents
,
Hypoglycemic Agents
Additional Keywords
:
Plant Extracts
[+]
A polyphenolic-rich blueberry extract can inhibit Giardia duodenalis and Cryptosporidium parvum.
Aug 01, 2007
Click here to read the entire abstract
Pubmed Data
: Methods. 2007 Aug;42(4):339-48. PMID:
17560322
Article Published Date
: Aug 01, 2007
Study Type
: In Vitro Study
Additional Links
Substances
:
Blueberry
,
Flavonoids
,
Polyphenols
Diseases
:
Cryptosporidiosis
,
Giardiasis
,
Protozoan Infections
Pharmacological Actions
:
Antiprotozoal Agents
Additional Keywords
:
Plant Extracts
[+]
A review of phenolic compounds as beneficial phytochemicals in pomegranate.
Sep 29, 2018
Click here to read the entire abstract
Pubmed Data
: Food Chem. 2018 Sep 30 ;261:75-86. Epub 2018 Apr 13. PMID:
29739608
Article Published Date
: Sep 29, 2018
Study Type
: Review
Additional Links
Substances
:
Anthocyanins
,
Cinnamic acid
,
Cyanidin
,
Delphinidin
,
Ellagic Acid
,
Flavonoids
,
Gallic Acid
,
Pomegranate
,
Punicalagin
[+]
A review of phytochemicals and their neuroprotective effects in the treatment of dementia.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2016 ;21(4). Epub 2016 Apr 21. PMID:
27110749
Article Published Date
: Dec 31, 2015
Study Type
: Review
Additional Links
Substances
:
Cannabidiol
,
Cannabinoids
,
Flavonoids
,
Polyphenols
Diseases
:
Alzheimer's Disease
,
Dementia
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Risk Reduction
[+]
A review of the anti-cancer natural products isolated from Chinese medicinal herbs.
Jul 21, 2011
Click here to read the entire abstract
Pubmed Data
: Chin Med. 2011 Jul 22 ;6(1):27. Epub 2011 Jul 22. PMID:
21777476
Article Published Date
: Jul 21, 2011
Study Type
: Review
Additional Links
Substances
:
Artemisinin
,
Berberine
,
Beta-Elemene
,
Curcumin
,
Emodin
,
Flavonoids
,
Ginsenosides
,
Shikonin
,
Silibinin
,
Ursolic Acid
,
Wogonin
Diseases
:
Cancers: All
Pharmacological Actions
:
Chemopreventive
,
Chemotherapeutic
Additional Keywords
:
Traditional Chinese Medicine
[+]
A review of the role of some commonly investigated phytochemicals and their epigenetic targets that are of particular interest in cancer prevention and cancer therapy.
Nov 30, 2014
Click here to read the entire abstract
Pubmed Data
: Cancer Lett. 2014 Dec 1 ;355(1):9-17. Epub 2014 Sep 16. PMID:
25236912
Article Published Date
: Nov 30, 2014
Study Type
: Review
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Cancers: All
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
Additional Keywords
:
Epigenetic Modification In Cancer
[+]
An apple flavonoid enriched fraction possessed a significantly stronger antiproliferative and specific action than Sorafenib in vitro.
Sep 24, 2014
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2014 Sep 25:1-10. Epub 2014 Sep 25. PMID:
25256427
Article Published Date
: Sep 24, 2014
Study Type
: In Vitro Study
Additional Links
Substances
:
Apple Polyphenols
,
Flavonoids
Diseases
:
Liver Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Caspase-3 Activation
,
Cell cycle arrest
,
Chemopreventive
,
Topoisomerase II Inhibitor
Additional Keywords
:
Northern Spy Apples
,
Plant Extracts
,
Selective Cytotoxicity
[+]
An extract of evening primrose (O. paradoxa) exhibits pro-oxidative and pro-apoptic against human skin melanoma cells.
Sep 23, 2009
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2009 Sep 23;57(18):8282-9. PMID:
19694434
Article Published Date
: Sep 23, 2009
Study Type
: In Vitro Study
Additional Links
Substances
:
Evening Primrose Oil
,
Flavonoids
,
Polyphenols
Diseases
:
Melanoma
Pharmacological Actions
:
Apoptotic
Additional Keywords
:
Plant Extracts
[+]
An in vitro study of the antioxidant and anti-inflammatory activities of 100 natural chemical compounds.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2015 ;2015:165457. Epub 2015 Oct 4. PMID:
26504472
Article Published Date
: Dec 31, 2014
Study Type
: In Vitro Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
[+]
An overview of phytotherapeutic approaches for the treatment of tuberculosis.
Dec 31, 2016
Click here to read the entire abstract
Pubmed Data
: Mini Rev Med Chem. 2017 ;17(2):167-183. PMID:
27145855
Article Published Date
: Dec 31, 2016
Study Type
: Review
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Mycobacterium tuberculosis
Pharmacological Actions
:
Anti-Bacterial Agents
Additional Keywords
:
Phytotherapy
[+]
Animal experimentation and cocoa interventions in humans support the anti-inflammatory effect of cocoa compounds.
Apr 08, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2016 Apr 9 ;8(4):212. Epub 2016 Apr 9. PMID:
27070643
Article Published Date
: Apr 08, 2016
Study Type
: Review
Additional Links
Substances
:
Cocoa
,
Flavonoids
Diseases
:
Atherosclerosis
,
Cardiovascular Diseases
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Anti-Inflammatory Agents
,
Atherosclerosis
,
Cancer
,
Cardiovascular Diseases
,
Cocoa
,
Flavonoids
,
Inflammation
,
Risk Reduction
[+]
Anthocyanins and flavanones are more bioavailable than previously perceived.
Jan 10, 2017
Click here to read the entire abstract
Pubmed Data
: Annu Rev Food Sci Technol. 2017 Jan 11. Epub 2017 Jan 11. PMID:
28125348
Article Published Date
: Jan 10, 2017
Study Type
: Review
Additional Links
Substances
:
Anthocyanins
,
Flavonoids
Additional Keywords
:
Anthocyanins
,
Bioavailability
,
Flavonoids
[+]
Antioxidant properties of raisins.
Nov 30, 2009
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2009 Dec ;12(6):1302-9. PMID:
20041785
Article Published Date
: Nov 30, 2009
Study Type
: In Vitro Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
,
Raisins
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Plant Extracts
[+]
Antioxidant, cholinesterase inhibition activities and essential oil analysis of Nelumbo nucifera seeds.
May 31, 2016
Click here to read the entire abstract
Pubmed Data
: Nat Prod Res. 2016 Jun ;30(11):1335-8. Epub 2015 Jul 27. PMID:
26212099
Article Published Date
: May 31, 2016
Study Type
: In Vitro Study
Additional Links
Substances
:
Flavonoids
,
Lotus
Pharmacological Actions
:
Acetylcholinesterase Inhibitor
,
Antioxidants
Additional Keywords
:
Essential Oils
[+]
Antioxidants have been shown to significantly influence cell growth, DNA repair and mitochondrial membrane-mediated apoptosis.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2014 ;15(9):16226-45. Epub 2014 Sep 15. PMID:
25226533
Article Published Date
: Dec 31, 2013
Study Type
: Review
Additional Links
Substances
:
Flavonoids
,
Ginsenosides
,
Polyphenols
,
Ursolic Acid
Diseases
:
Cancers: All
,
DNA damage
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anti-metastatic
,
Antioxidants
,
Antiproliferative
,
Apoptotic
,
Cyclooxygenase 2 Inhibitors
,
DNA Repair Up-regulation
Additional Keywords
:
Gene Expression Regulation
[+]
Apigenin and luteolin are potent inhibitors of human thyroid cancer cell lines.
Apr 01, 1999
Click here to read the entire abstract
Pubmed Data
: Thyroid. 1999 Apr;9(4):369-76. PMID:
10319943
Article Published Date
: Apr 01, 1999
Study Type
: In Vitro Study
Additional Links
Substances
:
Apigenin
,
Flavonoids
,
Luteolin
Diseases
:
Thyroid Cancer
Pharmacological Actions
:
Antiproliferative
Additional Keywords
:
Drug: Tamoxifen
[+]
Apigenin induces programmed cell death in fibroblast-like synovial cells associated with the pathophysiology of rheumatoid arthritis.
Nov 10, 2009
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2009 Nov 10;182(1):29-36. Epub 2009 Aug 6. PMID:
19647729
Article Published Date
: Nov 10, 2009
Study Type
: In Vitro Study
Additional Links
Substances
:
Apigenin
,
Flavonoids
Diseases
:
Rheumatoid Arthritis
Pharmacological Actions
:
Apoptotic
[+]
Apigenin induces programmed cell death in human breast cancer cells.
Feb 06, 2004
Click here to read the entire abstract
Pubmed Data
: J Biol Chem. 2004 Feb 6;279(6):4479-89. Epub 2003 Nov 5. PMID:
14602723
Article Published Date
: Feb 06, 2004
Study Type
: In Vitro Study
Additional Links
Substances
:
Apigenin
,
Flavonoids
Diseases
:
Breast Cancer
Pharmacological Actions
:
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
,
Enzyme Inhibitors
[+]
Apigenin inhibits growth and induces programmed cell death in anaplastic thyroid cancer cells.
Sep 01, 1999
Click here to read the entire abstract
Pubmed Data
: Anticancer Res. 1999 Sep-Oct;19(5B):4297-303. PMID:
10628390
Article Published Date
: Sep 01, 1999
Study Type
: In Vitro Study
Additional Links
Substances
:
Apigenin
,
Flavonoids
Diseases
:
Thyroid Cancer
Pharmacological Actions
:
Apoptotic
[+]
Apigenin potentiates the anticancer activity of 5-fluorouracil against human colonrectal cancer cells.
Apr 01, 2009
Click here to read the entire abstract
Pubmed Data
: J Nat Med. 2009 Apr;63(2):124-9. Epub 2008 Dec 3. PMID:
19050992
Article Published Date
: Apr 01, 2009
Study Type
: In Vitro Study
Additional Links
Substances
:
Apigenin
,
Flavonoids
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Antiproliferative
Additional Keywords
:
Drug: 5-flourouracil
,
Drug-Plant-Vitamin Synergies
[+]
Apple phytochemical extracts inhibit proliferation of estrogen-dependent and estrogen-independent human breast cancer cells.
Dec 24, 2008
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2008 Dec 24;56(24):11661-7. PMID: