Flavonoids

Flavonoids

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Article Count - 289
Cumulative Knowledge - 942

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Quick Summary: Current access displays 2 out of 207 associated Diseases

Name	Cumulative Knowledge	Article Count	Focus Articles
Hypertension	117	13	Log in \| Sign up
Cholesterol: Oxidation	70	13	Log in \| Sign up

Quick Summary: Current access displays 2 out of 75 associated Pharmacological Actions

Name	Cumulative Knowledge	Article Count	Focus Articles
Antioxidants	189	79	Log in \| Sign up
Platelet Aggregation Inhibitors	62	7	Log in \| Sign up

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View the Evidence: Substances

"Dietary flavonoid for preventing colorectal neoplasms."

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Pubmed Data : Cochrane Database Syst Rev. 2012 ;8:CD009350. Epub 2012 Aug 15. PMID: 22895989

Article Published Date : Dec 31, 2011

Study Type : Meta Analysis

Additional Links

Substances : Flavonoids : CK(909) : AC(289)

Diseases : Colorectal Cancer : CK(877) : AC(321)

Cocoa products have blood-pressure lowering capacity.

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Pubmed Data : Am J Hypertens. 2010 Jan;23(1):97-103. Epub 2009 Nov 12. PMID: 19910929

Article Published Date : Jan 01, 2010

Study Type : Meta Analysis

Additional Links

Substances : Flavonoids : CK(909) : AC(289)

Diseases : Hypertension : CK(2783) : AC(271)

Pharmacological Actions : Hypotensive : CK(383) : AC(53)

Dark chocolate is superior to placebo in reducing systolic hypertension or diastolic prehypertension.

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Pubmed Data : BMC Med. 2010;8:39. Epub 2010 Jun 28. PMID: 20584271

Article Published Date : Jan 01, 2010

Study Type : Meta Analysis

Additional Links

Substances : Flavonoids : CK(909) : AC(289)

Diseases : Hypertension : CK(2783) : AC(271), Prehypertension : CK(1857) : AC(3)

Pharmacological Actions : Hypotensive : CK(383) : AC(53)

High polyphenol chocolate is effective in improving the atherosclerotic cholesterol profile in patients with diabetes by increasing HDL cholesterol and improving the cholesterol:HDL ratio.

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Pubmed Data : Diabet Med. 2010 Nov;27(11):1318-21. PMID: 20968113

Article Published Date : Nov 01, 2010

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(909) : AC(289), Polyphenols : CK(427) : AC(174)

Diseases : Cholesterol: LDL/HDL ratio : CK(432) : AC(58), Diabetes: Cardiovascular Illness : CK(666) : AC(104), HDL: Low : CK(255) : AC(45)

"Kidney function in metabolic syndrome may be improved with Pycnogenol®."

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Pubmed Data : Panminerva Med. 2010 Jun ;52(2 Suppl 1):27-32. PMID: 20657531

Article Published Date : May 31, 2010

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(909) : AC(289)

Diseases : Metabolic Syndrome X : CK(645) : AC(122)

Pharmacological Actions : Antihypertensive Agents : CK(196) : AC(38)

A Chinese green tea polyphenol extract has evident anti-plaque effect.

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Pubmed Data : Zhonghua Kou Qiang Yi Xue Za Zhi. 2000 Sep;35(5):383-4. PMID: 11780252

Article Published Date : Sep 01, 2000

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(909) : AC(289), Green Tea : CK(930) : AC(294), Polyphenols : CK(427) : AC(174)

Diseases : Dental Caries : CK(277) : AC(32)

A combination of apigenin and EGCG prevent colorectal cancer recurrence.

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Pubmed Data : World J Gastroenterol. 2008 Apr 14;14(14):2187-93. PMID: 18407592

Article Published Date : Apr 14, 2008

Study Type : Human Study

Additional Links

Substances : Apigenin : CK(76) : AC(51), Catechin : CK(403) : AC(130), Flavonoids : CK(909) : AC(289)

Diseases : Colorectal Cancer : CK(877) : AC(321)

Pharmacological Actions : Chemopreventive : CK(1528) : AC(382)

Additional Keywords : Risk Reduction : CK(1909) : AC(196)

A combination of diosmin and hesperidin significantly reduces bleeding in patients with acute internal hemorrhoids.

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Pubmed Data : Clin Ther. 2005 Jun;27(6):746-54. PMID: 16117981

Article Published Date : Jun 01, 2005

Study Type : Human Study

Additional Links

Substances : Diosmin : CK(184) : AC(31), Flavonoids : CK(909) : AC(289), Hesperidin : CK(160) : AC(38)

Diseases : Hemorrhoids : CK(122) : AC(13)

A combination of pine bark extract and nattokinase prevents venous thrombosis in long-haul flights.

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Pubmed Data : Angiology. 2003 Sep-Oct;54(5):531-9. PMID: 14565628

Article Published Date : Sep 01, 2003

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(909) : AC(289), Nattokinase : CK(61) : AC(7)

Diseases : Deep Vein Thrombosis : CK(511) : AC(10), Thromboembolism : CK(205) : AC(19), Thrombosis : CK(657) : AC(74)

Pharmacological Actions : Platelet Aggregation Inhibitors : CK(173) : AC(37)

A flavonoid supplement improves leg health and reduces fluid retention in premenopausal women.

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Pubmed Data : Phytomedicine. 2004 Jan;11(1):11-7. PMID: 14971717

Article Published Date : Jan 01, 2004

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(909) : AC(289)

Diseases : Premenstrual syndrome : CK(160) : AC(16)

Additional Keywords : Oligomeric Procyanidins : CK(10) : AC(1), Water Retention : CK(10) : AC(1)

A flavonol-rich diet may decrease the risk of advanced adenoma recurrence.

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cancer Epidemiol Biomarkers Prev. 2008 Jun ;17(6):1344-53. PMID: 18559549

Article Published Date : May 31, 2008

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(909) : AC(289)

Diseases : Colorectal Cancer : CK(877) : AC(321)

Pharmacological Actions : Chemopreventive : CK(1528) : AC(382)

A polyphenol-rich beverage reduces symptoms associated with the common cold.

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Pubmed Data : Br J Nutr. 2010 Oct;104(8):1156-64. Epub 2010 May 21. PMID: 20487584

Article Published Date : Oct 01, 2010

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(909) : AC(289), Polyphenols : CK(427) : AC(174)

Diseases : Common Cold : CK(473) : AC(56)

Acute consumption of flavanol-rich cocoa and the reversal of endothelial dysunfction in smokers.

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Pubmed Data : J Am Coll Cardiol. 2005 Oct 4;46(7):1276-83. PMID: 16198843

Article Published Date : Oct 04, 2005

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(909) : AC(289)

Diseases : Endothelial Dysfunction : CK(897) : AC(173), Smoking : CK(577) : AC(86)

Apple peel extract inhibits the growth of Helicobacter pylori, and attenuates damage to the gastric mucosa caused by neutrophils.

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Pubmed Data : J Agric Food Chem. 2009 Sep 9;57(17):7743-9. PMID: 19691323

Article Published Date : Sep 09, 2009

Study Type : Human Study

Additional Links

Substances : Apples : CK(179) : AC(57), Flavonoids : CK(909) : AC(289), Polyphenols : CK(427) : AC(174)

Diseases : Helicobacter Pylori Infection : CK(336) : AC(67)

Additional Keywords : Plant Extracts : CK(3775) : AC(1248), Proanthocyanidins : CK(159) : AC(46)

Bilberry has anti-inflammatory properties.

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Pubmed Data : Eur J Nutr. 2010 Sep;49(6):345-55. Epub 2010 Feb 2. PMID: 20119859

Article Published Date : Sep 01, 2010

Study Type : Human Study

Additional Links

Substances : Bilberry : CK(39) : AC(11), Flavonoids : CK(909) : AC(289), Polyphenols : CK(427) : AC(174)

Diseases : Inflammation : CK(1077) : AC(363), Lipopolysaccharide-Induced Toxicity : CK(227) : AC(128)

Pharmacological Actions : NF-kappaB Inhibitor : CK(595) : AC(401)

Blood pressure is reduced and insulin sensitivity increased in glucose-intolerant, hypertensive subjects after 15 days of consuming high-polyphenol dark chocolate.

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Pubmed Data : J Nutr. 2008 Sep;138(9):1671-6. PMID: 18716168

Article Published Date : Sep 01, 2008

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(909) : AC(289), Polyphenols : CK(427) : AC(174)

Diseases : Cardiovascular Diseases : CK(5138) : AC(641), Hypertension : CK(2783) : AC(271), Insulin Resistance : CK(1034) : AC(221)

Cocoa inhibits LDL oxidation both in vitro and ex vivo.

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Pubmed Data : Mutat Res. 1999 Apr 6;440(2):181-8. PMID: 11185658

Article Published Date : Apr 06, 1999

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(909) : AC(289), Polyphenols : CK(427) : AC(174)

Diseases : Arteriosclerosis : CK(2154) : AC(123), Cholesterol: Oxidation : CK(457) : AC(98)

Pharmacological Actions : Antioxidants : CK(3723) : AC(1318)

Cocoa powder and dark chocolate may favorably affect cardiovascular disease risk status by modestly reducing LDL oxidation susceptibility and increasing serum total antioxidant capacity and HDL-cholesterol concentrations.

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Pubmed Data : Am J Clin Nutr. 2001 Nov;74(5):596-602. PMID: 11684527

Article Published Date : Nov 01, 2001

Study Type : Human Study

Additional Links

Substances : Catechin : CK(403) : AC(130), Flavonoids : CK(909) : AC(289)

Diseases : Cardiovascular Diseases : CK(5138) : AC(641), Cholesterol: Oxidation : CK(457) : AC(98), HDL: Low : CK(255) : AC(45)

Pharmacological Actions : Antioxidants : CK(3723) : AC(1318)

Additional Keywords : Proanthocyanidins : CK(159) : AC(46)

Coffee appears to have a beneficial effect on pulmonary function, among non-smokers.

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Pubmed Data : Int J Cancer. 2010 Oct 15;127(8):1758-68. PMID: 19372215

Article Published Date : Oct 15, 2010

Study Type : Human Study

Additional Links

Substances : Coffee : CK(442) : AC(65), Flavonoids : CK(909) : AC(289), Polyphenols : CK(427) : AC(174)

Diseases : Pulmonary Diseases : CK(12) : AC(2), Smoking : CK(577) : AC(86)

Continuous intake of polyphenolic compounds containing cocoa powder reduces LDL oxidative susceptibility and has beneficial effects on plasma HDL-cholesterol concentrations in humans.

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Pubmed Data : Proc Natl Acad Sci U S A. 2009 Jun 2;106(22):9033-8. Epub 2009 May 18. PMID: 17344491

Article Published Date : Jun 02, 2009

Study Type : Human Study

Additional Links

Substances : Catechin : CK(403) : AC(130), Flavonoids : CK(909) : AC(289), Polyphenols : CK(427) : AC(174)

Diseases : Cholesterol: Oxidation : CK(457) : AC(98), HDL: Low : CK(255) : AC(45)

Pharmacological Actions : Antioxidants : CK(3723) : AC(1318)

Dark chocolate consumption increases HDL cholesterol concentration and chocolate fatty acids may inhibit lipid peroxidation in healthy humans.

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Pubmed Data : Food Chem Toxicol.2008 Dec;46(12):3586-92. Epub 2008 Sep 3 PMID: 15454274

Article Published Date : Dec 01, 2008

Study Type : Human Study

Additional Links

Substances : Chocolate : CK(243) : AC(32), Flavonoids : CK(909) : AC(289), Polyphenols : CK(427) : AC(174)

Diseases : Cholesterol: LDL/HDL ratio : CK(432) : AC(58), Cholesterol: Oxidation : CK(457) : AC(98), HDL: Low : CK(255) : AC(45)

Dark chocolate improves coronary vasomotion and reduces platelet reactivity.

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Pubmed Data : Circulation. 2007 Nov 20;116(21):2376-82. Epub 2007 Nov 5. PMID: 17984375

Article Published Date : Nov 20, 2007

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(909) : AC(289)

Diseases : Blood Platelet Disorders : CK(20) : AC(2), Clotting : CK(177) : AC(36), Coronary Artery Disease : CK(1305) : AC(136), Endothelial Dysfunction : CK(897) : AC(173)

Pharmacological Actions : Anti-Platelet : CK(117) : AC(31), Vasodilator Agents : CK(262) : AC(54)

Flavanone intake is inversely associated with esophageal cancer risk and may account, with vitamin C, for the protective effect of fruit, especially citrus fruit, on esophageal cancer.

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Pubmed Data : Arch Intern Med. 2000 Apr 10;160(7):1009-13. PMID: 17192901

Article Published Date : Apr 10, 2000

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(909) : AC(289), Fruit: All : CK(1836) : AC(472), Grapefruit : CK(109) : AC(30), Lemon Juice : CK(46) : AC(7), Orange : CK(127) : AC(28), Vitamin C : CK(1274) : AC(238)

Diseases : Esophageal Cancer : CK(328) : AC(55)

Additional Keywords : Risk Reduction : CK(1909) : AC(196)

Flavonoid antioxidants may have therapeutic value in PVCRD and DRD for the purpose of improving and stabilizing the visual functions and for neuroprotection.

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Pubmed Data : Inflamm Res. 2009 Aug;58(8):513-21. Epub 2009 Mar 11. PMID: 15384840

Article Published Date : Aug 01, 2009

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(909) : AC(289), Ginkgo biloba : CK(530) : AC(104)

Diseases : Dystrophic retinal detachment (DRD) : CK(11) : AC(2), Eye Diseases: Vitreous Disorders : CK(12) : AC(3), Peripheral vitreochoreoretinal dystrophies (PVCRD) : CK(10) : AC(1), Retinal Detachment : CK(12) : AC(2)

Pharmacological Actions : Antioxidants : CK(3723) : AC(1318)

Flavonoid consumption reduces the risk of esophageal cancer.

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2007 Jun;21(6):501-6. PMID: 19444905

Article Published Date : Jun 01, 2007

Study Type : Human Study

Additional Links

Substances : Anthocyanins : CK(56) : AC(19), Flavonoids : CK(909) : AC(289)

Diseases : Esophageal Cancer : CK(328) : AC(55)

Additional Keywords : Proanthocyanidins : CK(159) : AC(46), Risk Reduction : CK(1909) : AC(196)

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