Flavonoids

Flavonoids

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Article Count - 301
Cumulative Knowledge - 966

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Quick Summary: Current access displays 2 out of 217 associated Diseases

Name	Cumulative Knowledge	Article Count	Focus Articles
Hypertension	117	13	Log in \| Sign up
Endothelial Dysfunction	77	12	Log in \| Sign up

Quick Summary: Current access displays 2 out of 79 associated Pharmacological Actions

Name	Cumulative Knowledge	Article Count	Focus Articles
Antioxidants	187	81	Log in \| Sign up
Platelet Aggregation Inhibitors	62	7	Log in \| Sign up

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View the Evidence: Substances

"Dietary flavonoid for preventing colorectal neoplasms."

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Pubmed Data : Cochrane Database Syst Rev. 2012 ;8:CD009350. Epub 2012 Aug 15. PMID: 22895989

Article Published Date : Dec 31, 2011

Study Type : Meta Analysis

Additional Links

Substances : Flavonoids : CK(960) : AC(301)

Diseases : Colorectal Cancer : CK(909) : AC(333)

Cocoa products have blood-pressure lowering capacity.

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Pubmed Data : Am J Hypertens. 2010 Jan;23(1):97-103. Epub 2009 Nov 12. PMID: 19910929

Article Published Date : Jan 01, 2010

Study Type : Meta Analysis

Additional Links

Substances : Flavonoids : CK(960) : AC(301)

Diseases : Hypertension : CK(2886) : AC(285)

Pharmacological Actions : Hypotensive : CK(405) : AC(57)

Dark chocolate is superior to placebo in reducing systolic hypertension or diastolic prehypertension.

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Pubmed Data : BMC Med. 2010;8:39. Epub 2010 Jun 28. PMID: 20584271

Article Published Date : Jan 01, 2010

Study Type : Meta Analysis

Additional Links

Substances : Flavonoids : CK(960) : AC(301)

Diseases : Hypertension : CK(2886) : AC(285), Prehypertension : CK(1857) : AC(3)

Pharmacological Actions : Hypotensive : CK(405) : AC(57)

High polyphenol chocolate is effective in improving the atherosclerotic cholesterol profile in patients with diabetes by increasing HDL cholesterol and improving the cholesterol:HDL ratio.

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Pubmed Data : Diabet Med. 2010 Nov;27(11):1318-21. PMID: 20968113

Article Published Date : Nov 01, 2010

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(960) : AC(301), Polyphenols : CK(484) : AC(182)

Diseases : Cholesterol: LDL/HDL ratio : CK(462) : AC(58), Diabetes: Cardiovascular Illness : CK(690) : AC(106), HDL: Low : CK(285) : AC(48)

"Kidney function in metabolic syndrome may be improved with Pycnogenol®."

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Pubmed Data : Panminerva Med. 2010 Jun ;52(2 Suppl 1):27-32. PMID: 20657531

Article Published Date : May 31, 2010

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(960) : AC(301)

Diseases : Metabolic Syndrome X : CK(675) : AC(124)

Pharmacological Actions : Antihypertensive Agents : CK(246) : AC(45)

A Chinese green tea polyphenol extract has evident anti-plaque effect.

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Pubmed Data : Zhonghua Kou Qiang Yi Xue Za Zhi. 2000 Sep;35(5):383-4. PMID: 11780252

Article Published Date : Sep 01, 2000

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(960) : AC(301), Green Tea : CK(952) : AC(278), Polyphenols : CK(484) : AC(182)

Diseases : Dental Caries : CK(277) : AC(38)

A combination of apigenin and EGCG prevent colorectal cancer recurrence.

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Pubmed Data : World J Gastroenterol. 2008 Apr 14;14(14):2187-93. PMID: 18407592

Article Published Date : Apr 14, 2008

Study Type : Human Study

Additional Links

Substances : Apigenin : CK(81) : AC(54), Catechin : CK(409) : AC(134), Flavonoids : CK(960) : AC(301)

Diseases : Colorectal Cancer : CK(909) : AC(333)

Pharmacological Actions : Chemopreventive : CK(1617) : AC(395)

Additional Keywords : Risk Reduction : CK(1929) : AC(197)

A combination of diosmin and hesperidin significantly reduces bleeding in patients with acute internal hemorrhoids.

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Pubmed Data : Clin Ther. 2005 Jun;27(6):746-54. PMID: 16117981

Article Published Date : Jun 01, 2005

Study Type : Human Study

Additional Links

Substances : Diosmin : CK(173) : AC(29), Flavonoids : CK(960) : AC(301), Hesperidin : CK(160) : AC(38)

Diseases : Hemorrhoids : CK(122) : AC(13)

A combination of pine bark extract and nattokinase prevents venous thrombosis in long-haul flights.

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Pubmed Data : Angiology. 2003 Sep-Oct;54(5):531-9. PMID: 14565628

Article Published Date : Sep 01, 2003

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(960) : AC(301), Nattokinase : CK(61) : AC(7)

Diseases : Deep Vein Thrombosis : CK(511) : AC(10), Thromboembolism : CK(205) : AC(16), Thrombosis : CK(295) : AC(74)

Pharmacological Actions : Platelet Aggregation Inhibitors : CK(183) : AC(38)

A flavonoid supplement improves leg health and reduces fluid retention in premenopausal women.

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Pubmed Data : Phytomedicine. 2004 Jan;11(1):11-7. PMID: 14971717

Article Published Date : Jan 01, 2004

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(960) : AC(301)

Diseases : Premenstrual syndrome : CK(180) : AC(18)

Additional Keywords : Oligomeric Procyanidins : CK(10) : AC(1), Water Retention : CK(10) : AC(1)

A flavonol-rich diet may decrease the risk of advanced adenoma recurrence.

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cancer Epidemiol Biomarkers Prev. 2008 Jun ;17(6):1344-53. PMID: 18559549

Article Published Date : May 31, 2008

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(960) : AC(301)

Diseases : Colorectal Cancer : CK(909) : AC(333)

Pharmacological Actions : Chemopreventive : CK(1617) : AC(395)

A polyphenol-rich beverage reduces symptoms associated with the common cold.

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Pubmed Data : Br J Nutr. 2010 Oct;104(8):1156-64. Epub 2010 May 21. PMID: 20487584

Article Published Date : Oct 01, 2010

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(960) : AC(301), Polyphenols : CK(484) : AC(182)

Diseases : Common Cold : CK(483) : AC(57)

Acute consumption of flavanol-rich cocoa and the reversal of endothelial dysunfction in smokers.

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Pubmed Data : J Am Coll Cardiol. 2005 Oct 4;46(7):1276-83. PMID: 16198843

Article Published Date : Oct 04, 2005

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(960) : AC(301)

Diseases : Endothelial Dysfunction : CK(933) : AC(181), Smoking : CK(597) : AC(87)

Apple peel extract inhibits the growth of Helicobacter pylori, and attenuates damage to the gastric mucosa caused by neutrophils.

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Pubmed Data : J Agric Food Chem. 2009 Sep 9;57(17):7743-9. PMID: 19691323

Article Published Date : Sep 09, 2009

Study Type : Human Study

Additional Links

Substances : Apples : CK(189) : AC(60), Flavonoids : CK(960) : AC(301), Polyphenols : CK(484) : AC(182)

Diseases : Helicobacter Pylori Infection : CK(337) : AC(68)

Additional Keywords : Plant Extracts : CK(3910) : AC(1282), Proanthocyanidins : CK(170) : AC(48)

Bilberry has anti-inflammatory properties.

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Pubmed Data : Eur J Nutr. 2010 Sep;49(6):345-55. Epub 2010 Feb 2. PMID: 20119859

Article Published Date : Sep 01, 2010

Study Type : Human Study

Additional Links

Substances : Bilberry : CK(39) : AC(11), Flavonoids : CK(960) : AC(301), Polyphenols : CK(484) : AC(182)

Diseases : Inflammation : CK(1125) : AC(377), Lipopolysaccharide-Induced Toxicity : CK(235) : AC(138)

Pharmacological Actions : NF-kappaB Inhibitor : CK(616) : AC(417)

Blood pressure is reduced and insulin sensitivity increased in glucose-intolerant, hypertensive subjects after 15 days of consuming high-polyphenol dark chocolate.

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Pubmed Data : J Nutr. 2008 Sep;138(9):1671-6. PMID: 18716168

Article Published Date : Sep 01, 2008

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(960) : AC(301), Polyphenols : CK(484) : AC(182)

Diseases : Cardiovascular Diseases : CK(5342) : AC(665), Hypertension : CK(2886) : AC(285), Insulin Resistance : CK(1131) : AC(235)

Cocoa inhibits LDL oxidation both in vitro and ex vivo.

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Pubmed Data : Mutat Res. 1999 Apr 6;440(2):181-8. PMID: 11185658

Article Published Date : Apr 06, 1999

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(960) : AC(301), Polyphenols : CK(484) : AC(182)

Diseases : Arteriosclerosis : CK(452) : AC(126), Cholesterol: Oxidation : CK(468) : AC(105)

Pharmacological Actions : Antioxidants : CK(3864) : AC(1373)

Cocoa powder and dark chocolate may favorably affect cardiovascular disease risk status by modestly reducing LDL oxidation susceptibility and increasing serum total antioxidant capacity and HDL-cholesterol concentrations.

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Pubmed Data : Am J Clin Nutr. 2001 Nov;74(5):596-602. PMID: 11684527

Article Published Date : Nov 01, 2001

Study Type : Human Study

Additional Links

Substances : Catechin : CK(409) : AC(134), Flavonoids : CK(960) : AC(301)

Diseases : Cardiovascular Diseases : CK(5342) : AC(665), Cholesterol: Oxidation : CK(468) : AC(105), HDL: Low : CK(285) : AC(48)

Pharmacological Actions : Antioxidants : CK(3864) : AC(1373)

Additional Keywords : Proanthocyanidins : CK(170) : AC(48)

Coffee appears to have a beneficial effect on pulmonary function, among non-smokers.

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Pubmed Data : Int J Cancer. 2010 Oct 15;127(8):1758-68. PMID: 19372215

Article Published Date : Oct 15, 2010

Study Type : Human Study

Additional Links

Substances : Coffee : CK(442) : AC(65), Flavonoids : CK(960) : AC(301), Polyphenols : CK(484) : AC(182)

Diseases : Pulmonary Diseases : CK(12) : AC(2), Smoking : CK(597) : AC(87)

Continuous intake of polyphenolic compounds containing cocoa powder reduces LDL oxidative susceptibility and has beneficial effects on plasma HDL-cholesterol concentrations in humans.

Click here to read the entire abstract

Pubmed Data : Proc Natl Acad Sci U S A. 2009 Jun 2;106(22):9033-8. Epub 2009 May 18. PMID: 17344491

Article Published Date : Jun 02, 2009

Study Type : Human Study

Additional Links

Substances : Catechin : CK(409) : AC(134), Flavonoids : CK(960) : AC(301), Polyphenols : CK(484) : AC(182)

Diseases : Cholesterol: Oxidation : CK(468) : AC(105), HDL: Low : CK(285) : AC(48)

Pharmacological Actions : Antioxidants : CK(3864) : AC(1373)

Dark chocolate consumption increases HDL cholesterol concentration and chocolate fatty acids may inhibit lipid peroxidation in healthy humans.

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Pubmed Data : Food Chem Toxicol.2008 Dec;46(12):3586-92. Epub 2008 Sep 3 PMID: 15454274

Article Published Date : Dec 01, 2008

Study Type : Human Study

Additional Links

Substances : Chocolate : CK(286) : AC(38), Flavonoids : CK(960) : AC(301), Polyphenols : CK(484) : AC(182)

Diseases : Cholesterol: LDL/HDL ratio : CK(462) : AC(58), Cholesterol: Oxidation : CK(468) : AC(105), HDL: Low : CK(285) : AC(48)

Dark chocolate improves coronary vasomotion and reduces platelet reactivity.

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Pubmed Data : Circulation. 2007 Nov 20;116(21):2376-82. Epub 2007 Nov 5. PMID: 17984375

Article Published Date : Nov 20, 2007

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(960) : AC(301)

Diseases : Blood Platelet Disorders : CK(20) : AC(2), Clotting : CK(164) : AC(34), Coronary Artery Disease : CK(1305) : AC(137), Endothelial Dysfunction : CK(933) : AC(181)

Pharmacological Actions : Anti-Platelet : CK(118) : AC(32), Vasodilator Agents : CK(262) : AC(54)

Flavanone intake is inversely associated with esophageal cancer risk and may account, with vitamin C, for the protective effect of fruit, especially citrus fruit, on esophageal cancer.

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Pubmed Data : Arch Intern Med. 2000 Apr 10;160(7):1009-13. PMID: 17192901

Article Published Date : Apr 10, 2000

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(960) : AC(301), Fruit: All : CK(2019) : AC(488), Grapefruit : CK(106) : AC(29), Lemon Juice : CK(46) : AC(7), Orange : CK(126) : AC(28), Vitamin C : CK(1304) : AC(256)

Diseases : Esophageal Cancer : CK(330) : AC(58)

Additional Keywords : Risk Reduction : CK(1929) : AC(197)

Flavonoid antioxidants may have therapeutic value in PVCRD and DRD for the purpose of improving and stabilizing the visual functions and for neuroprotection.

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Pubmed Data : Inflamm Res. 2009 Aug;58(8):513-21. Epub 2009 Mar 11. PMID: 15384840

Article Published Date : Aug 01, 2009

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(960) : AC(301), Ginkgo biloba : CK(541) : AC(108)

Diseases : Dystrophic retinal detachment (DRD) : CK(11) : AC(2), Eye Diseases: Vitreous Disorders : CK(12) : AC(3), Peripheral vitreochoreoretinal dystrophies (PVCRD) : CK(10) : AC(1), Retinal Detachment : CK(12) : AC(2)

Pharmacological Actions : Antioxidants : CK(3864) : AC(1373)

Flavonoid consumption reduces the risk of esophageal cancer.

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2007 Jun;21(6):501-6. PMID: 19444905

Article Published Date : Jun 01, 2007

Study Type : Human Study

Additional Links

Substances : Anthocyanins : CK(60) : AC(22), Flavonoids : CK(960) : AC(301)

Diseases : Esophageal Cancer : CK(330) : AC(58)

Additional Keywords : Proanthocyanidins : CK(170) : AC(48), Risk Reduction : CK(1929) : AC(197)

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