Flavonoids

Flavonoids

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Article Count - 289
Cumulative Knowledge - 932

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Quick Summary: Current access displays 2 out of 207 associated Diseases

Name	Cumulative Knowledge	Article Count	Focus Articles
Hypertension	117	13	Log in \| Sign up
Cholesterol: Oxidation	70	13	Log in \| Sign up

Quick Summary: Current access displays 2 out of 75 associated Pharmacological Actions

Name	Cumulative Knowledge	Article Count	Focus Articles
Antioxidants	189	79	Log in \| Sign up
Platelet Aggregation Inhibitors	62	7	Log in \| Sign up

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View the Evidence: Substances

"Dietary flavonoid for preventing colorectal neoplasms."

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Pubmed Data : Cochrane Database Syst Rev. 2012 ;8:CD009350. Epub 2012 Aug 15. PMID: 22895989

Article Published Date : Dec 31, 2011

Study Type : Meta Analysis

Additional Links

Substances : Flavonoids : CK(909) : AC(289)

Diseases : Colorectal Cancer : CK(877) : AC(321)

Cocoa products have blood-pressure lowering capacity.

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Pubmed Data : Am J Hypertens. 2010 Jan;23(1):97-103. Epub 2009 Nov 12. PMID: 19910929

Article Published Date : Jan 01, 2010

Study Type : Meta Analysis

Additional Links

Substances : Flavonoids : CK(909) : AC(289)

Diseases : Hypertension : CK(2783) : AC(271)

Pharmacological Actions : Hypotensive : CK(383) : AC(53)

Dark chocolate is superior to placebo in reducing systolic hypertension or diastolic prehypertension.

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Pubmed Data : BMC Med. 2010;8:39. Epub 2010 Jun 28. PMID: 20584271

Article Published Date : Jan 01, 2010

Study Type : Meta Analysis

Additional Links

Substances : Flavonoids : CK(909) : AC(289)

Diseases : Hypertension : CK(2783) : AC(271), Prehypertension : CK(1857) : AC(3)

Pharmacological Actions : Hypotensive : CK(383) : AC(53)

High polyphenol chocolate is effective in improving the atherosclerotic cholesterol profile in patients with diabetes by increasing HDL cholesterol and improving the cholesterol:HDL ratio.

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Pubmed Data : Diabet Med. 2010 Nov;27(11):1318-21. PMID: 20968113

Article Published Date : Nov 01, 2010

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(909) : AC(289), Polyphenols : CK(427) : AC(174)

Diseases : Cholesterol: LDL/HDL ratio : CK(432) : AC(58), Diabetes: Cardiovascular Illness : CK(666) : AC(104), HDL: Low : CK(255) : AC(45)

"Kidney function in metabolic syndrome may be improved with Pycnogenol®."

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Pubmed Data : Panminerva Med. 2010 Jun ;52(2 Suppl 1):27-32. PMID: 20657531

Article Published Date : May 31, 2010

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(909) : AC(289)

Diseases : Metabolic Syndrome X : CK(645) : AC(122)

Pharmacological Actions : Antihypertensive Agents : CK(196) : AC(38)

A Chinese green tea polyphenol extract has evident anti-plaque effect.

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Pubmed Data : Zhonghua Kou Qiang Yi Xue Za Zhi. 2000 Sep;35(5):383-4. PMID: 11780252

Article Published Date : Sep 01, 2000

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(909) : AC(289), Green Tea : CK(930) : AC(294), Polyphenols : CK(427) : AC(174)

Diseases : Dental Caries : CK(277) : AC(32)

A combination of apigenin and EGCG prevent colorectal cancer recurrence.

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Pubmed Data : World J Gastroenterol. 2008 Apr 14;14(14):2187-93. PMID: 18407592

Article Published Date : Apr 14, 2008

Study Type : Human Study

Additional Links

Substances : Apigenin : CK(76) : AC(51), Catechin : CK(403) : AC(130), Flavonoids : CK(909) : AC(289)

Diseases : Colorectal Cancer : CK(877) : AC(321)

Pharmacological Actions : Chemopreventive : CK(1528) : AC(382)

Additional Keywords : Risk Reduction : CK(1909) : AC(196)

A combination of diosmin and hesperidin significantly reduces bleeding in patients with acute internal hemorrhoids.

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Pubmed Data : Clin Ther. 2005 Jun;27(6):746-54. PMID: 16117981

Article Published Date : Jun 01, 2005

Study Type : Human Study

Additional Links

Substances : Diosmin : CK(184) : AC(31), Flavonoids : CK(909) : AC(289), Hesperidin : CK(160) : AC(38)

Diseases : Hemorrhoids : CK(122) : AC(13)

A combination of pine bark extract and nattokinase prevents venous thrombosis in long-haul flights.

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Pubmed Data : Angiology. 2003 Sep-Oct;54(5):531-9. PMID: 14565628

Article Published Date : Sep 01, 2003

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(909) : AC(289), Nattokinase : CK(61) : AC(7)

Diseases : Deep Vein Thrombosis : CK(511) : AC(10), Thromboembolism : CK(205) : AC(19), Thrombosis : CK(657) : AC(74)

Pharmacological Actions : Platelet Aggregation Inhibitors : CK(173) : AC(37)

A flavonoid supplement improves leg health and reduces fluid retention in premenopausal women.

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Pubmed Data : Phytomedicine. 2004 Jan;11(1):11-7. PMID: 14971717

Article Published Date : Jan 01, 2004

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(909) : AC(289)

Diseases : Premenstrual syndrome : CK(160) : AC(16)

Additional Keywords : Oligomeric Procyanidins : CK(10) : AC(1), Water Retention : CK(10) : AC(1)

A flavonol-rich diet may decrease the risk of advanced adenoma recurrence.

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cancer Epidemiol Biomarkers Prev. 2008 Jun ;17(6):1344-53. PMID: 18559549

Article Published Date : May 31, 2008

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(909) : AC(289)

Diseases : Colorectal Cancer : CK(877) : AC(321)

Pharmacological Actions : Chemopreventive : CK(1528) : AC(382)

A polyphenol-rich beverage reduces symptoms associated with the common cold.

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Pubmed Data : Br J Nutr. 2010 Oct;104(8):1156-64. Epub 2010 May 21. PMID: 20487584

Article Published Date : Oct 01, 2010

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(909) : AC(289), Polyphenols : CK(427) : AC(174)

Diseases : Common Cold : CK(473) : AC(56)

Acute consumption of flavanol-rich cocoa and the reversal of endothelial dysunfction in smokers.

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Pubmed Data : J Am Coll Cardiol. 2005 Oct 4;46(7):1276-83. PMID: 16198843

Article Published Date : Oct 04, 2005

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(909) : AC(289)

Diseases : Endothelial Dysfunction : CK(897) : AC(173), Smoking : CK(577) : AC(86)

Apple peel extract inhibits the growth of Helicobacter pylori, and attenuates damage to the gastric mucosa caused by neutrophils.

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Pubmed Data : J Agric Food Chem. 2009 Sep 9;57(17):7743-9. PMID: 19691323

Article Published Date : Sep 09, 2009

Study Type : Human Study

Additional Links

Substances : Apples : CK(179) : AC(57), Flavonoids : CK(909) : AC(289), Polyphenols : CK(427) : AC(174)

Diseases : Helicobacter Pylori Infection : CK(305) : AC(61)

Additional Keywords : Plant Extracts : CK(3775) : AC(1248), Proanthocyanidins : CK(159) : AC(46)

Bilberry has anti-inflammatory properties.

Click here to read the entire abstract

Pubmed Data : Eur J Nutr. 2010 Sep;49(6):345-55. Epub 2010 Feb 2. PMID: 20119859

Article Published Date : Sep 01, 2010

Study Type : Human Study

Additional Links

Substances : Bilberry : CK(39) : AC(11), Flavonoids : CK(909) : AC(289), Polyphenols : CK(427) : AC(174)

Diseases : Inflammation : CK(1077) : AC(363), Lipopolysaccharide-Induced Toxicity : CK(227) : AC(128)

Pharmacological Actions : NF-kappaB Inhibitor : CK(595) : AC(401)

Blood pressure is reduced and insulin sensitivity increased in glucose-intolerant, hypertensive subjects after 15 days of consuming high-polyphenol dark chocolate.

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Pubmed Data : J Nutr. 2008 Sep;138(9):1671-6. PMID: 18716168

Article Published Date : Sep 01, 2008

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(909) : AC(289), Polyphenols : CK(427) : AC(174)

Diseases : Cardiovascular Diseases : CK(5138) : AC(641), Hypertension : CK(2783) : AC(271), Insulin Resistance : CK(1034) : AC(221)

Cocoa inhibits LDL oxidation both in vitro and ex vivo.

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Pubmed Data : Mutat Res. 1999 Apr 6;440(2):181-8. PMID: 11185658

Article Published Date : Apr 06, 1999

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(909) : AC(289), Polyphenols : CK(427) : AC(174)

Diseases : Arteriosclerosis : CK(2154) : AC(123), Cholesterol: Oxidation : CK(457) : AC(98)

Pharmacological Actions : Antioxidants : CK(3723) : AC(1318)

Cocoa powder and dark chocolate may favorably affect cardiovascular disease risk status by modestly reducing LDL oxidation susceptibility and increasing serum total antioxidant capacity and HDL-cholesterol concentrations.

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Pubmed Data : Am J Clin Nutr. 2001 Nov;74(5):596-602. PMID: 11684527

Article Published Date : Nov 01, 2001

Study Type : Human Study

Additional Links

Substances : Catechin : CK(403) : AC(130), Flavonoids : CK(909) : AC(289)

Diseases : Cardiovascular Diseases : CK(5138) : AC(641), Cholesterol: Oxidation : CK(457) : AC(98), HDL: Low : CK(255) : AC(45)

Pharmacological Actions : Antioxidants : CK(3723) : AC(1318)

Additional Keywords : Proanthocyanidins : CK(159) : AC(46)

Coffee appears to have a beneficial effect on pulmonary function, among non-smokers.

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Pubmed Data : Int J Cancer. 2010 Oct 15;127(8):1758-68. PMID: 19372215

Article Published Date : Oct 15, 2010

Study Type : Human Study

Additional Links

Substances : Coffee : CK(442) : AC(65), Flavonoids : CK(909) : AC(289), Polyphenols : CK(427) : AC(174)

Diseases : Pulmonary Diseases : CK(12) : AC(2), Smoking : CK(577) : AC(86)

Continuous intake of polyphenolic compounds containing cocoa powder reduces LDL oxidative susceptibility and has beneficial effects on plasma HDL-cholesterol concentrations in humans.

Click here to read the entire abstract

Pubmed Data : Proc Natl Acad Sci U S A. 2009 Jun 2;106(22):9033-8. Epub 2009 May 18. PMID: 17344491

Article Published Date : Jun 02, 2009

Study Type : Human Study

Additional Links

Substances : Catechin : CK(403) : AC(130), Flavonoids : CK(909) : AC(289), Polyphenols : CK(427) : AC(174)

Diseases : Cholesterol: Oxidation : CK(457) : AC(98), HDL: Low : CK(255) : AC(45)

Pharmacological Actions : Antioxidants : CK(3723) : AC(1318)

Dark chocolate consumption increases HDL cholesterol concentration and chocolate fatty acids may inhibit lipid peroxidation in healthy humans.

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Pubmed Data : Food Chem Toxicol.2008 Dec;46(12):3586-92. Epub 2008 Sep 3 PMID: 15454274

Article Published Date : Dec 01, 2008

Study Type : Human Study

Additional Links

Substances : Chocolate : CK(243) : AC(32), Flavonoids : CK(909) : AC(289), Polyphenols : CK(427) : AC(174)

Diseases : Cholesterol: LDL/HDL ratio : CK(432) : AC(58), Cholesterol: Oxidation : CK(457) : AC(98), HDL: Low : CK(255) : AC(45)

Dark chocolate improves coronary vasomotion and reduces platelet reactivity.

Click here to read the entire abstract

Pubmed Data : Circulation. 2007 Nov 20;116(21):2376-82. Epub 2007 Nov 5. PMID: 17984375

Article Published Date : Nov 20, 2007

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(909) : AC(289)

Diseases : Blood Platelet Disorders : CK(20) : AC(2), Clotting : CK(177) : AC(36), Coronary Artery Disease : CK(1305) : AC(136), Endothelial Dysfunction : CK(897) : AC(173)

Pharmacological Actions : Anti-Platelet : CK(117) : AC(31), Vasodilator Agents : CK(262) : AC(54)

Flavanone intake is inversely associated with esophageal cancer risk and may account, with vitamin C, for the protective effect of fruit, especially citrus fruit, on esophageal cancer.

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Pubmed Data : Arch Intern Med. 2000 Apr 10;160(7):1009-13. PMID: 17192901

Article Published Date : Apr 10, 2000

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(909) : AC(289), Fruit: All : CK(1836) : AC(472), Grapefruit : CK(109) : AC(30), Lemon Juice : CK(46) : AC(7), Orange : CK(127) : AC(28), Vitamin C : CK(1274) : AC(238)

Diseases : Esophageal Cancer : CK(328) : AC(55)

Additional Keywords : Risk Reduction : CK(1909) : AC(196)

Flavonoid antioxidants may have therapeutic value in PVCRD and DRD for the purpose of improving and stabilizing the visual functions and for neuroprotection.

Click here to read the entire abstract

Pubmed Data : Inflamm Res. 2009 Aug;58(8):513-21. Epub 2009 Mar 11. PMID: 15384840

Article Published Date : Aug 01, 2009

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(909) : AC(289), Ginkgo biloba : CK(530) : AC(104)

Diseases : Dystrophic retinal detachment (DRD) : CK(11) : AC(2), Eye Diseases: Vitreous Disorders : CK(12) : AC(3), Peripheral vitreochoreoretinal dystrophies (PVCRD) : CK(10) : AC(1), Retinal Detachment : CK(12) : AC(2)

Pharmacological Actions : Antioxidants : CK(3723) : AC(1318)

Flavonoid consumption reduces the risk of esophageal cancer.

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2007 Jun;21(6):501-6. PMID: 19444905

Article Published Date : Jun 01, 2007

Study Type : Human Study

Additional Links

Substances : Anthocyanins : CK(56) : AC(19), Flavonoids : CK(909) : AC(289)

Diseases : Esophageal Cancer : CK(328) : AC(55)

Additional Keywords : Proanthocyanidins : CK(159) : AC(46), Risk Reduction : CK(1909) : AC(196)

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