Flavonoids

Flavonoids

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View the Evidence: Substances

Muskmelon, watermelon and mango fruit may have an ameliorative effect on atherogenic diet induced dyslipidemia, hypothyroidism and hyperglycemia in rats.

Pubmed Data : Biofactors. 2008;33(1):13-24. PMID: 19276533
Article Published Date : Jan 01, 2008
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(909) : AC(289), Mango : CK(60) : AC(34), Muskmelon : CK(2) : AC(1), Polyphenols : CK(427) : AC(174), Vitamin C : CK(1274) : AC(238), Watermelon : CK(48) : AC(9)
Diseases : Arteriosclerosis : CK(2154) : AC(123), Dyslipidemias : CK(176) : AC(33), Hyperglycemia : CK(2892) : AC(59), Hypothyroidism : CK(537) : AC(78), Oxidative Stress : CK(1945) : AC(710)
Pharmacological Actions : Hypoglycemic Agents : CK(563) : AC(156)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Nutritional antioxidants such as green tea polyphenols and tetrahydrocurcumin may beneficially modify the life span of animals.

Pubmed Data : Biogerontology. 2007 Oct;8(5):567-73. Epub 2007 May 22. PMID: 17516143
Article Published Date : Oct 01, 2007
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(909) : AC(289), Green Tea : CK(930) : AC(294), Polyphenols : CK(427) : AC(174), Tetrahydrocurcumin : CK(37) : AC(20)
Diseases : Aging : CK(1351) : AC(369)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Olive leaf contains phenolics with radioprotective properties.

Pubmed Data : J Hepatol. 1994 Jan;20(1):41-6. PMID: 12495584
Article Published Date : Jan 01, 1994
Study Type : Animal Study
Additional Links
Substances : Diosmin : CK(184) : AC(31), Flavonoids : CK(909) : AC(289), Olive leaf extract : CK(132) : AC(26), Rutin : CK(93) : AC(30)
Diseases : Radiation Induced Illness : CK(1018) : AC(249)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Radioprotective : CK(456) : AC(183)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Onion flesh and onion peel enhance antioxidant status in aged rats.

Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2007 Feb;53(1):21-9. PMID: 17484375
Article Published Date : Feb 01, 2007
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(909) : AC(289), Onion : CK(452) : AC(42), Polyphenols : CK(427) : AC(174), Quercetin : CK(318) : AC(136)
Diseases : Aging : CK(1351) : AC(369), DNA damage : CK(711) : AC(293)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Orange peel flavonoids inhibit experimental adjuvant-induced rat arthritis.

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2010 May;35(10):1298-301. PMID: 20707201
Article Published Date : May 01, 2010
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(909) : AC(289), Orange : CK(127) : AC(28)
Diseases : Arthritis : CK(1430) : AC(218), Inflammation : CK(1077) : AC(363), Osteoarthritis : CK(615) : AC(91)
Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)
Additional Keywords : Adjuvant-Induced Injury : CK(11) : AC(6), Plant Extracts : CK(3572) : AC(1216)

Peppermint protects against radiation-induced testicular damage.

Pubmed Data : Basic Clin Pharmacol Toxicol. 2009 Apr;104(4):329-34. PMID: 19320637
Article Published Date : Apr 01, 2009
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(909) : AC(289), Peppermint : CK(300) : AC(48)
Diseases : Lipid Peroxidation : CK(403) : AC(127), Radiation Induced Illness : CK(1018) : AC(249)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Radioprotective : CK(456) : AC(183)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Phyllanthus amarus has radioprotective properties.

Pubmed Data : Ann Oncol. 2009 Jan;20(1):160-5. Epub 2008 Jul 31. PMID: 19461166
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(909) : AC(289), Phyllanthus amarus : CK(21) : AC(9), Polyphenols : CK(427) : AC(174)
Diseases : Radiation Induced Illness : CK(1018) : AC(249)
Pharmacological Actions : Radioprotective : CK(456) : AC(183)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Pine need extract is anti-inflammatory and has a protective effect on cholesteorl oxidation.

Pubmed Data : Food Chem Toxicol. 2008 Jan;46(1):175-85. Epub 2007 Jul 28. PMID: 17804140
Article Published Date : Jan 01, 2008
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(909) : AC(289), Pine Needle : CK(10) : AC(6), Polyphenols : CK(427) : AC(174)
Diseases : Cholesterol: Oxidation : CK(457) : AC(98), Lipopolysaccharide-Induced Toxicity : CK(227) : AC(128)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Cyclooxygenase 2 Inhibitors : CK(269) : AC(169), Enzyme Inhibitors : CK(372) : AC(208)

Plantain extract has neutralizing properties on snake venom induced toxicity.

Pubmed Data : J Ethnopharmacol. 2005 Apr 8;98(1-2):21-9. PMID: 15763360
Article Published Date : Apr 08, 2005
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(909) : AC(289), Plantain : CK(39) : AC(12), Polyphenols : CK(427) : AC(174), Tannic Acid : CK(20) : AC(16)
Diseases : Snake Bite: Venom Toxicity : CK(8) : AC(5)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Pretreatment with black tea polyphenols positively modulates xenobiotic-metabolizing enzymes in an experimental oral carcinogenesis model.

Pubmed Data : Oncol Res. 2008;17(2):75-85. PMID: 18543609
Article Published Date : Jan 01, 2008
Study Type : Animal Study
Additional Links
Substances : Black Tea : CK(158) : AC(40), Flavonoids : CK(909) : AC(289)
Diseases : DNA damage : CK(711) : AC(293), Oral Cancer : CK(66) : AC(43)
Pharmacological Actions : Chemopreventive : CK(1528) : AC(382), Phase II Detoxification Enzyme Inducer : CK(64) : AC(32)

Propolis has radioprotective properties.

Pubmed Data : Toxicol Appl Pharmacol. 2006 Sep 15;215(3):295-305. Epub 2006 May 18. PMID: 17473440
Article Published Date : Sep 15, 2006
Study Type : Animal Study
Additional Links
Substances : Bee Propolis : CK(220) : AC(83), Flavonoids : CK(909) : AC(289), Polyphenols : CK(427) : AC(174)
Diseases : Radiation Induced Illness : CK(1018) : AC(249)
Pharmacological Actions : Radioprotective : CK(456) : AC(183)

Pterocarpus marsupium exhibits antihyperlipidemic activities.

Pubmed Data : Eur J Cancer. 2006 Feb;42(3):415-21. Epub 2006 Jan 4. PMID: 8377021
Article Published Date : Feb 01, 2006
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(909) : AC(289), Pterocarpus marsupium : CK(26) : AC(9)
Diseases : Cholesterol: LDL/HDL ratio : CK(432) : AC(58), Hyperlipidemia : CK(1211) : AC(109)
Pharmacological Actions : Anticholesteremic Agents : CK(669) : AC(142)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Pycnogenol accelerates wound healing and reduces scar formation.

Pubmed Data : Phytother Res. 2004 Jul;18(7):579-81. PMID: 15305320
Article Published Date : Jul 01, 2004
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(909) : AC(289), Pycnogenol (Pine Bark) : CK(385) : AC(61)
Diseases : Scars : CK(19) : AC(7), Wound Healing : CK(235) : AC(72)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Pycnogenol ameliorate experimental inflammatory bowel diseases.

Pubmed Data : Phytother Res. 2004 Dec;18(12):1027-8. PMID: 15742344
Article Published Date : Dec 01, 2004
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(909) : AC(289), Pycnogenol (Pine Bark) : CK(385) : AC(61)
Diseases : Inflammatory Bowel Diseases : CK(1227) : AC(103)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Red wine polyphenols prevent hypertension and endothelial dysfunction in rats.

Pubmed Data : Cardiovasc Res. 2006 Sep 1;71(4):794-802. Epub 2006 May 26. PMID: 16822492
Article Published Date : Sep 01, 2006
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(909) : AC(289), Polyphenols : CK(427) : AC(174), Red Wine Extract : CK(59) : AC(25)
Diseases : Endothelial Dysfunction : CK(897) : AC(173), Hypertension : CK(2783) : AC(271)
Pharmacological Actions : Cardioprotective : CK(702) : AC(196), Vasodilator Agents : CK(262) : AC(54)

Resveratrol exhibits anti-inflammatory properties related to inhibition of tumour necrosis factor-alpha (TNF-alpha) pre-mRNA splicing.

Pubmed Data : Fitoterapia. 2004 Jun;75(3-4):375-7. PMID: 19945165
Article Published Date : Jun 01, 2004
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(909) : AC(289), Polyphenols : CK(427) : AC(174), Resveratrol : CK(977) : AC(590), Stilbenes : CK(128) : AC(92)
Diseases : Inflammation : CK(1077) : AC(363)
Pharmacological Actions : Anti-Inflammatory Agents : CK(1230) : AC(433), Interleukin-1 beta downregulation : CK(177) : AC(70), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)

Rhus verniciflua stokes (Sumac) contains compounds which exhibit anti-inflammatory and anti-angiogenic activity in rheumatoid arthritis synovial cells and in vivo modles.

Pubmed Data : Int Immunopharmacol. 2009 Mar;9(3):268-76. Epub 2008 Dec 25. PMID: 19111632
Article Published Date : Mar 01, 2009
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(909) : AC(289), Sumac : CK(37) : AC(16)
Diseases : Rheumatoid Arthritis : CK(424) : AC(64)
Pharmacological Actions : Anti-Angiogenic : CK(143) : AC(101), Anti-Inflammatory Agents : CK(1230) : AC(433), Enzyme Inhibitors : CK(372) : AC(208)

Rutin inhibits nitric oxide and tumor necrosis factor-alpha production in lipopolysaccharide and concanavalin-a stimulated macrophages.

Pubmed Data : Drug Metabol Drug Interact. 2007;22(4):263-78. PMID: 18447002
Article Published Date : Jan 01, 2007
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(909) : AC(289), Rutin : CK(93) : AC(30)
Diseases : Lipopolysaccharide-Induced Toxicity : CK(227) : AC(128)
Pharmacological Actions : Nitric Oxide Inhibitor : CK(108) : AC(57), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)

Serum C-reactive protein concentrations are inversely associated with dietary flavonoid intake in U.S. adults.

Pubmed Data : J Nutr. 2008 Apr;138(4):753-60. PMID: 18356331
Article Published Date : Apr 01, 2008
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(909) : AC(289)
Diseases : C-Reactive Protein : CK(819) : AC(74)
Additional Keywords : Risk Reduction : CK(1909) : AC(196)

Silymarin has radioprotective properties.

Pubmed Data : Z Naturforsch C. 2010 May-Jun;65(5-6):337-46. PMID: 20653235
Article Published Date : May 01, 2010
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(909) : AC(289), Milk Thistle : CK(226) : AC(55)
Diseases : Radiation Induced Illness : CK(1018) : AC(249)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), NF-kappaB Inhibitor : CK(595) : AC(401), Radioprotective : CK(456) : AC(183)

Soybean and green tea polyphenols improve immune function and redox status in very old ovariectomized mice.

Pubmed Data : Rejuvenation Res. 2010 Dec;13(6):665-74. Epub 2010 Sep 6. PMID: 20818935
Article Published Date : Dec 01, 2010
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(909) : AC(289), Green Tea : CK(930) : AC(294), Polyphenols : CK(427) : AC(174), Soy : CK(1672) : AC(347), Tea : CK(989) : AC(234)
Diseases : Aging : CK(1351) : AC(369), Aging: Immunosenecence : CK(52) : AC(11), Lipid Peroxidation : CK(403) : AC(127), Ovariectomy Associated Adverse Changes : CK(18) : AC(7)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Interleukin-10 downregulation : CK(73) : AC(21), Interleukin-6 Downregulation : CK(470) : AC(135)

The consumption of dietary polyphenols (wine) with foods (turkey meat) containing oxidized fats reduces potentially harmful oxidative stress.

Pubmed Data : J Agric Food Chem. 2008 Jul 9;56(13):5002-7. Epub 2008 Jun 10. PMID: 18540628
Article Published Date : Jul 09, 2008
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(909) : AC(289), Polyphenols : CK(427) : AC(174), Wine : CK(132) : AC(35)
Diseases : Oxidative Stress : CK(1945) : AC(710)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

The flavonoid baicalin found in Chinese skullcap protects against cerebrovascular dysfunction and brain inflammation in experimental heatstroke.

Pubmed Data : Neuropharmacology. 2007 Mar;52(3):1024-33. Epub 2007 Jan 3. PMID: 17204294
Article Published Date : Mar 01, 2007
Study Type : Animal Study
Additional Links
Substances : Catechols : CK(14) : AC(12), Chinese Skullcap : CK(97) : AC(57), Flavonoids : CK(909) : AC(289)
Diseases : Brain Inflammation : CK(79) : AC(35), Heat Stroke : CK(5) : AC(2)

The flavonoid extracted from citrus known as luteolin reduces Alzheimer's disease beta-amyloid plaque production in mice.

Pubmed Data : J Cell Mol Med. 2009 Mar;13(3):574-88. Epub 2008 Apr 9. PMID: 18410522
Article Published Date : Mar 01, 2009
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(909) : AC(289), Luteolin : CK(62) : AC(51)
Diseases : Alzheimer's Disease : CK(826) : AC(160)

The flavonoid fraction of broccoli inhibits selenite-induced cataract formation in an animal model.

Pubmed Data : Curr Eye Res. 2010 Feb;35(2):99-107. PMID: 20136419
Article Published Date : Feb 01, 2010
Study Type : Animal Study
Additional Links
Substances : Broccoli : CK(449) : AC(185), Flavonoids : CK(909) : AC(289)
Diseases : Cataract : CK(182) : AC(55)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216), Sodium Selenite : CK(39) : AC(18)

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