Histidine

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11 Diseases Researched for Histidine

Name	AC	CK
Uremia	2	20
Acetaminophen (Tylenol) Toxicity	1	2
Alcohol Toxicity	1	2
Alcoholic Liver Disease	1	2
Cholesterol: Oxidation	1	2
Colitis	1	2
Diabetes: Cardiovascular Illness	1	2
Diabetes: Glycation/A1C	1	2
High Homocysteine	1	2
Lipopolysaccharide-Induced Toxicity	1	2
Myocardial Infarction	1	2

6 Pharmacological Actions Researched for Histidine

Name	AC	CK
Interleukin-6 Downregulation	3	6
Tumor Necrosis Factor (TNF) Alpha Inhibitor	3	6
Antioxidants	1	2
Cardioprotective	1	2
Hepatoprotective	1	2
NF-kappaB Inhibitor	1	2

Research Articles 9
Cumulative Knowledge Score 14
Overall Research Rating GOOD

View the Evidence:
9 Abstracts with Histidine Research

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A protein-poor diet and supplementation with essential amino acids improves the general condition of uremic patients and lower serum urea nitrogen levels. - Article 1Jan 01, 1975

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Pubmed Data : Clin Nephrol. 1975;3(5):187-94. PMID: 1149343

Article Published Date : Jan 01, 1975

Study Type : Human Study

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Substances : Amino Acids, Histidine

Diseases : Uremia

Therapeutic Actions : Dietary Modification: Low-Protein Diet

[+]

A protein-poor diet and supplementation with essential amino acids improves the general condition of uremic patients and lower serum urea nitrogen levels. - Article 2Jan 01, 1975

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Pubmed Data : Clin Nephrol. 1975;3(5):195-203. PMID: 1149344

Article Published Date : Jan 01, 1975

Study Type : Human Study

Additional Links

Substances : Amino Acids, Histidine

Diseases : Uremia

Therapeutic Actions : Dietary Modification: Low-Protein Diet

[+]

Carnosine and histidine have a protective effect on acetaminophen-induced liver injury.Oct 01, 2009

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Pubmed Data : J Food Sci. 2009 Oct;74(8):H259-65. PMID: 19799668

Article Published Date : Oct 01, 2009

Study Type : Animal Study

Additional Links

Substances : Carnosine, Histidine

Diseases : Acetaminophen (Tylenol) Toxicity

Pharmacological Actions : Hepatoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Dietary histidine ameliorates mouse colitis through the inhibition of proinflammatory cytokine production from macrophages.Feb 01, 2009

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Pubmed Data : Gastroenterology. 2009 Feb;136(2):564-74.e2. Epub 2008 Oct 7. PMID: 19027739

Article Published Date : Feb 01, 2009

Study Type : Animal Study

Additional Links

Substances : Histidine

Diseases : Colitis, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Histidine and carnosine delay diabetic deterioration in mice and protect human low density lipoprotein against oxidation and glycation.Jun 01, 2008

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Pubmed Data : Cont Lens Anterior Eye. 2008 Jun;31(3):141-6; quiz 170. Epub 2008 Mar 4. PMID: 15878720

Article Published Date : Jun 01, 2008

Study Type : Animal Study

Additional Links

Substances : Carnosine, Histidine

Diseases : Cholesterol: Oxidation, Diabetes: Cardiovascular Illness, Diabetes: Glycation/A1C

Pharmacological Actions : Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Histidine and vitamin C produced a synergistic inhibitory effect on isoproterenol-induced cardiotoxicity.Dec 31, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Vet Res Forum. 2016 ;7(1):47-54. Epub 2016 Mar 15. PMID: 27226887

Article Published Date : Dec 31, 2015

Study Type : Animal Study

Additional Links

Substances : Histidine, Vitamin C

Diseases : Myocardial Infarction

Pharmacological Actions : Antioxidants, Cardioprotective

[+]

Histidine appears to have anti-oxidant and anti-inflammatory effects, useful in the treatment of chronic alcoholic liver injury.May 01, 2008

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Pubmed Data : Food Chem Toxicol. 2008 May;46(5):1503-9. Epub 2008 Jan 25. PMID: 18222027

Article Published Date : May 01, 2008

Study Type : Animal Study

Additional Links

Substances : Carnosine, Histidine

Diseases : Alcohol Toxicity , Alcoholic Liver Disease

Pharmacological Actions : Interleukin-6 Downregulation

[+]

L-Glutamic acid, L-histidine, and L-arginine significantly suppressed methionine-induced enhancement of plasma homocysteine concentrationsJul 01, 2008

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Pubmed Data : Biosci Biotechnol Biochem. 2008 Jul;72(7):1940-3. Epub 2008 Jul 7. PMID: 18603771

Article Published Date : Jul 01, 2008

Study Type : Animal Study

Additional Links

Substances : Arginine, Histidine

Diseases : High Homocysteine

[+]

Histidine suppresses food intake and fat accumulation in rats.Nov 01, 2004

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Pubmed Data : Nutrition. 2004 Nov-Dec;20(11-12):991-6. PMID: 15561489

Article Published Date : Nov 01, 2004

Additional Links

Substances : Histidine

Research Articles 9
Cumulative Knowledge Score 14
Overall Research Rating GOOD

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This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

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View the Evidence: 9 Abstracts with Histidine Research

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A protein-poor diet and supplementation with essential amino acids improves the general condition of uremic patients and lower serum urea nitrogen levels. - Article 1Jan 01, 1975

A protein-poor diet and supplementation with essential amino acids improves the general condition of uremic patients and lower serum urea nitrogen levels. - Article 2Jan 01, 1975

Carnosine and histidine have a protective effect on acetaminophen-induced liver injury.Oct 01, 2009

Dietary histidine ameliorates mouse colitis through the inhibition of proinflammatory cytokine production from macrophages.Feb 01, 2009

Histidine and carnosine delay diabetic deterioration in mice and protect human low density lipoprotein against oxidation and glycation.Jun 01, 2008

Histidine and vitamin C produced a synergistic inhibitory effect on isoproterenol-induced cardiotoxicity.Dec 31, 2015

Histidine appears to have anti-oxidant and anti-inflammatory effects, useful in the treatment of chronic alcoholic liver injury.May 01, 2008

L-Glutamic acid, L-histidine, and L-arginine significantly suppressed methionine-induced enhancement of plasma homocysteine concentrationsJul 01, 2008

Histidine suppresses food intake and fat accumulation in rats.Nov 01, 2004

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Histidine

View the Evidence:
9 Abstracts with Histidine Research