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Additional Topics Details for this Page
Article Count
- 124
Cumulative Knowledge
- 629
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View the Evidence: Substances
Exposure to isoflavone-containing soy products may improve endothelial function.
Click here to read the entire abstract
Pubmed Data
: Nutr Metab Cardiovasc Dis. 2010 Aug 14. Epub 2010 Aug 14. PMID:
20709515
Article Published Date
: Aug 14, 2010
Study Type
: Meta Analysis
Additional Links
Substances
:
Isoflavones : CK(627) : AC(124)
,
phytoestrogens : CK(699) : AC(210)
,
Soy : CK(1688) : AC(350)
,
Soy Protein : CK(2307) : AC(56)
Diseases
:
Cardiac Mortality : CK(703) : AC(67)
,
Coronary Artery Disease : CK(1305) : AC(136)
,
Endothelial Dysfunction : CK(897) : AC(173)
Safety Study: There is little evidence that in those with normal thyroid function soy has any adverse effects. In those with hypothyroidism adequate iodine should be consumed to counterbalance the soy consumption.
Click here to read the entire abstract
Pubmed Data
: Thyroid. 2006 Mar;16(3):249-58. PMID:
16571087
Article Published Date
: Mar 01, 2006
Study Type
: Meta Analysis
Additional Links
Substances
:
Isoflavones : CK(627) : AC(124)
,
Soy : CK(1688) : AC(350)
,
Soy Protein : CK(2307) : AC(56)
Diseases
:
Hypothyroidism : CK(537) : AC(78)
A combination of soy, isoflavones, lycopene, silymarin and antoxidants significantly increases PSA doubling time in men with prostate cancer.
Click here to read the entire abstract
Pubmed Data
: Eur Urol. 2005 Dec;48(6):922-30; discussion 930-1. Epub 2005 Oct 17. PMID:
16263208
Article Published Date
: Dec 01, 2005
Study Type
: Human Study
Additional Links
Substances
:
Antioxidant formulas : CK(487) : AC(73)
,
Isoflavones : CK(627) : AC(124)
,
Lycopene : CK(194) : AC(38)
,
Milk Thistle : CK(226) : AC(55)
,
Soy : CK(1688) : AC(350)
Diseases
:
Prostate: PSA Doubling : CK(133) : AC(16)
,
Prostate Cancer : CK(998) : AC(288)
A daily supplement of soy protein prevents the increase in subcutaneous and total abdominal fat in postmenopausal women.
Click here to read the entire abstract
Pubmed Data
: Fertil Steril. 2007 Dec;88(6):1609-17. Epub 2007 Apr 6. PMID:
17412329
Article Published Date
: Dec 01, 2007
Study Type
: Human Study
Additional Links
Substances
:
Isoflavones : CK(627) : AC(124)
,
Soy Protein : CK(2307) : AC(56)
Diseases
:
Abdominal Obesity (Midsection Fat) : CK(348) : AC(53)
A high intake of soy and isoflavones may be associated with a reduced prevalence of allergic rhinitis.
Click here to read the entire abstract
Pubmed Data
: J Allergy Clin Immunol. 2005 Jun;115(6):1176-83. PMID:
15940131
Article Published Date
: Jun 01, 2005
Study Type
: Human Study
Additional Links
Substances
:
Isoflavones : CK(627) : AC(124)
,
Soy Protein : CK(2307) : AC(56)
Diseases
:
Allergic Rhinitis : CK(318) : AC(40)
Additional Keywords
:
Risk Reduction : CK(1909) : AC(196)
A higher intake of soy foods and soy isoflavones is associated with lower sperm concentration.
Click here to read the entire abstract
Pubmed Data
: Hum Reprod. 2008 Nov;23(11):2584-90. Epub 2008 Jul 23. PMID:
18650557
Article Published Date
: Nov 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Isoflavones : CK(627) : AC(124)
,
Soy : CK(1688) : AC(350)
Diseases
:
Infertility: Male : CK(209) : AC(52)
A soy rich diet may prevent the vaginal atrophy in postmenopause.
Click here to read the entire abstract
Pubmed Data
: Vascul Pharmacol. 2008 Jan;48(1):14-20. Epub 2007 Nov 13. PMID:
12927310
Article Published Date
: Jan 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Isoflavones : CK(627) : AC(124)
,
Soy Protein : CK(2307) : AC(56)
Diseases
:
Estrogen Deficiency : CK(57) : AC(19)
,
Postmenopausal Disorders : CK(285) : AC(35)
,
Vaginal Atrophy : CK(10) : AC(1)
,
Vaginal Diseases : CK(20) : AC(2)
Capsaicin and isoflavone promotes hair growth in mice and humans with alopecia.
Click here to read the entire abstract
Pubmed Data
: Growth Horm IGF Res. 2007 Oct;17(5):408-15. Epub 2007 Jun 13. PMID:
17569567
Article Published Date
: Oct 01, 2007
Study Type
: Human Study
Additional Links
Substances
:
Cayenne : CK(139) : AC(20)
,
Isoflavones : CK(627) : AC(124)
Diseases
:
Alopecia : CK(131) : AC(28)
Additional Keywords
:
Insulin-Like Growth Factor : CK(10) : AC(1)
Daidzein-rich isoflavone are effective in reducing hot flashes in menopausal women.
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2007 Apr 24;80(20):1821-31. Epub 2007 Feb 3. PMID:
18257146
Article Published Date
: Apr 24, 2007
Study Type
: Human Study
Additional Links
Substances
:
Daidzein : CK(965) : AC(28)
,
Isoflavones : CK(627) : AC(124)
Diseases
:
Hot Flash : CK(203) : AC(19)
,
Menopausal Syndrome : CK(171) : AC(27)
Dietary intake of isoflavone is inversely associated with the risk of lower urinary tract symptoms.
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2007 Dec;98(6):1237-42. Epub 2007 Jul 19. PMID:
17640419
Article Published Date
: Dec 01, 2007
Study Type
: Human Study
Additional Links
Substances
:
Genistein : CK(450) : AC(174)
,
Isoflavones : CK(627) : AC(124)
,
Soy : CK(1688) : AC(350)
Diseases
:
Lower Urinary Tract Symptoms : CK(12) : AC(2)
,
Prostatic Hyperplasia: Benign : CK(202) : AC(46)
Dietary intake of isoflavones and polyunsaturated fatty acids associated with a Japanese diet reduce lung dysfunction, breathlessness and the prevalence of chronic obstructive pulmonary disease.
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2010 Jan 28. Epub 2010 Jan 28. PMID:
20112297
Article Published Date
: Jan 28, 2010
Study Type
: Human Study
Additional Links
Substances
:
Isoflavones : CK(627) : AC(124)
,
Polyunsaturated Fatty Acids (PUFAs) : CK(98) : AC(14)
Diseases
:
COPD : CK(158) : AC(18)
,
Smoking : CK(577) : AC(86)
Therapeutic Actions
:
Dietary Modification: Traditional Japanese Diet : CK(20) : AC(2)
Dietary isoflavone consumption is inversely associated with fibrocystic breast disease.
Click here to read the entire abstract
Pubmed Data
: Cancer Epidemiol Biomarkers Prev. 2007 Dec;16(12):2579-86. PMID:
18086761
Article Published Date
: Dec 01, 2007
Study Type
: Human Study
Additional Links
Substances
:
Isoflavones : CK(627) : AC(124)
Diseases
:
Fibrocystic Breast Disease : CK(62) : AC(7)
Dietary soy improves the inflammatory and nutritional status in end-stage renal disease patients on chronic hemodialysis
Click here to read the entire abstract
Pubmed Data
: Nephrol Dial Transplant. 2006 Aug;21(8):2239-46. Epub 2006 Jun 9. PMID:
16766544
Article Published Date
: Aug 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Isoflavones : CK(627) : AC(124)
Diseases
:
C-Reactive Protein : CK(819) : AC(74)
,
Hemodialysis : CK(393) : AC(38)
,
Inflammation : CK(1077) : AC(363)
,
Kidney Failure : CK(668) : AC(41)
Pharmacological Actions
:
Interleukin-6 Downregulation : CK(470) : AC(135)
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)
Fermented soy therapy may have therapeutic value in treating platinum-resistant ovarian cancer.
Click here to read the entire abstract
Pubmed Data
: Gynecol Oncol. 2006 Jan;100(1):205-9. Epub 2005 Sep 19. PMID:
16171852
Article Published Date
: Jan 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Daidzein : CK(965) : AC(28)
,
Genistein : CK(450) : AC(174)
,
Isoflavones : CK(627) : AC(124)
,
Soy : CK(1688) : AC(350)
Diseases
:
Cancers: Drug Resistant : CK(225) : AC(147)
,
Ovarian Cancer : CK(154) : AC(58)
Additional Keywords
:
Drug: Doxorubicin : CK(141) : AC(55)
Frequent miso soup and isoflavone consumption is associated with a reduced risk of breast cancer in Japanese women.
Click here to read the entire abstract
Pubmed Data
: J Natl Cancer Inst. 2003 Jun 18;95(12):906-13. PMID:
12813174
Article Published Date
: Jun 18, 2003
Study Type
: Human Study
Additional Links
Substances
:
Fermented Foods and Beverages : CK(670) : AC(133)
,
Isoflavones : CK(627) : AC(124)
,
Miso : CK(307) : AC(4)
,
Soy : CK(1688) : AC(350)
Diseases
:
Breast Cancer : CK(2361) : AC(621)
Pharmacological Actions
:
Chemopreventive : CK(1528) : AC(382)
Additional Keywords
:
Risk Reduction : CK(1909) : AC(196)
Genistein and daidzein consumption are associated with a lower risk of prostate cancer.
Click here to read the entire abstract
Pubmed Data
: J Altern Complement Med. 2009 Aug;15(8):905-9. PMID:
19838933
Article Published Date
: Aug 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Daidzein : CK(965) : AC(28)
,
Genistein : CK(450) : AC(174)
,
Isoflavones : CK(627) : AC(124)
Diseases
:
Prostate Cancer: Prevention : CK(155) : AC(16)
Pharmacological Actions
:
Anticarcinogenic Agents : CK(521) : AC(275)
,
Chemopreventive : CK(1528) : AC(382)
Additional Keywords
:
Risk Reduction : CK(1909) : AC(196)
High dietary intake of soy isoflavones was associated with lower risk of recurrence among post-menopausal patients with breast cancer positive for estrogen and progesterone receptor and those who were receiving anastrozole (Arimidex) as endocrine therapy.
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2010 Feb;13(1):179-88. PMID:
20956506
Article Published Date
: Feb 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Isoflavones : CK(627) : AC(124)
,
Soy : CK(1688) : AC(350)
Diseases
:
Breast Cancer : CK(2361) : AC(621)
Additional Keywords
:
Drug: Anastrozole : CK(10) : AC(1)
,
Drug Synergy : CK(327) : AC(147)
High isoflavone intake is associated with reduced risk of cerebral and myocardial infarction in Japanese women.
Click here to read the entire abstract
Pubmed Data
: Circulation. 2007 Nov 27;116(22):2553-62. Epub 2007 Nov 19. PMID:
18025534
Article Published Date
: Nov 27, 2007
Study Type
: Human Study
Additional Links
Substances
:
Isoflavones : CK(627) : AC(124)
Diseases
:
Myocardial Infarction : CK(2632) : AC(117)
,
Stroke : CK(540) : AC(47)
Isoflavone intake was associated with a decreased risk of lung cancer.
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2010 Jan 13. Epub 2010 Jan 13. PMID:
20071645
Article Published Date
: Jan 13, 2010
Study Type
: Human Study
Additional Links
Substances
:
Isoflavones : CK(627) : AC(124)
,
Soy : CK(1688) : AC(350)
Diseases
:
Lung Cancer : CK(496) : AC(198)
Pharmacological Actions
:
Chemopreventive : CK(1528) : AC(382)
Additional Keywords
:
Risk Reduction : CK(1909) : AC(196)
Isoflavone supplementation improves menopausal symptoms only in women with the ability to produce equol.
Click here to read the entire abstract
Pubmed Data
: Int J Gynaecol Obstet. 2008 Jul;102(1):44-9. Epub 2008 Apr 8. PMID:
18395723
Article Published Date
: Jul 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Daidzein : CK(965) : AC(28)
,
Equol : CK(33) : AC(10)
,
Isoflavones : CK(627) : AC(124)
Diseases
:
Menopausal Syndrome : CK(171) : AC(27)
Isoflavone supplementation reduces C-reactive protein and reverses endothelial dysfunction in patients with ischaemic stroke.
Click here to read the entire abstract
Pubmed Data
: Eur Heart J. 2008 Nov;29(22):2800-7. Epub 2008 Sep 23. PMID:
18812325
Article Published Date
: Nov 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Isoflavones : CK(627) : AC(124)
Diseases
:
Arteriosclerosis : CK(2154) : AC(123)
,
C-Reactive Protein : CK(819) : AC(74)
,
Cerebral Ischemia : CK(263) : AC(50)
,
Endothelial Dysfunction : CK(897) : AC(173)
,
Stroke : CK(540) : AC(47)
Isoflavone-rich soy protein suppresses androgen receptor expression in men at high risk of prostate cancer.
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2007 Jul;137(7):1769-75. PMID:
17585029
Article Published Date
: Jul 01, 2007
Study Type
: Human Study
Additional Links
Substances
:
Isoflavones : CK(627) : AC(124)
,
Soy : CK(1688) : AC(350)
Diseases
:
Androgen-Induced Diseases : CK(49) : AC(20)
,
Prostate Cancer : CK(998) : AC(288)
Isoflavones attenuate bone loss and have a potentially protective effect on the lumbar spine in women
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2004 Feb;79(2):326-33. PMID:
14749241
Article Published Date
: Feb 01, 2004
Study Type
: Human Study
Additional Links
Substances
:
Isoflavones : CK(627) : AC(124)
,
Red Clover : CK(36) : AC(9)
Diseases
:
Osteoporosis : CK(1171) : AC(205)
Isoflavones from soy foods have therapeutic value in treating perimenstrual symptoms.
Click here to read the entire abstract
Pubmed Data
: Taehan Kanho Hakhoe Chi. 2007 Apr;37(3):276-85. PMID:
17615448
Article Published Date
: Apr 01, 2007
Study Type
: Human Study
Additional Links
Substances
:
Isoflavones : CK(627) : AC(124)
Diseases
:
Perimenopausal Syndrome : CK(52) : AC(6)
Isoflavones, taken orally, reduced blood pressure and central arterial stiffness indicating reduced cardiovascular risk.
Click here to read the entire abstract
Pubmed Data
: Atherosclerosis. 2007 May;192(1):184-9. Epub 2006 May 30. PMID:
16730732
Article Published Date
: May 01, 2007
Study Type
: Human Study
Additional Links
Substances
:
Isoflavones : CK(627) : AC(124)
Diseases
:
Arterial Hardening: Elasticity : CK(128) : AC(17)
,
Hypertension : CK(2783) : AC(271)
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