Kava Kava

Kava Kava

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Article Count - 39
Cumulative Knowledge - 229

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Quick Summary: Current access displays 2 out of 24 associated Diseases

Name	Cumulative Knowledge	Article Count	Focus Articles
Anxiety Disorders	157	14	Log in \| Sign up
Depression: Unipolar	30	2	Log in \| Sign up

Quick Summary: Current access displays 2 out of 15 associated Pharmacological Actions

Name	Cumulative Knowledge	Article Count	Focus Articles
Anxiolytic	54	6	Log in \| Sign up
Antidepressive Agents	10	1	Log in \| Sign up

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View the Evidence: Substances

Kava contains a compound which induces programmed cell death in prostate cancer cells.

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Pubmed Data : Indian J Exp Biol. 2007 Jun;45(6):524-8. PMID: 20112340

Article Published Date : Jun 01, 2007

Study Type : In Vitro Study

Additional Links

Substances : Flavonoids : CK(909) : AC(289), Kava Kava : CK(239) : AC(39)

Diseases : Prostate Cancer : CK(998) : AC(288)

Pharmacological Actions : Antiproliferative : CK(1052) : AC(775), Apoptotic : CK(1489) : AC(1114)

Kava contains a compound which protects against neurodegeneration.

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Pubmed Data : Bioorg Med Chem. 2010 May 1;18(9):3133-9. Epub 2010 Mar 20. PMID: 20371185

Article Published Date : May 01, 2010

Study Type : In Vitro Study

Additional Links

Substances : Kava Kava : CK(239) : AC(39)

Diseases : Neurodegenerative Diseases : CK(1743) : AC(420)

Pharmacological Actions : Neuroprotective Agents : CK(962) : AC(480)

Kava contains compounds with Cyclooxygenase enzyme inhibitory and antioxidant properties.

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Pubmed Data : Phytomedicine. 2002 Jan;9(1):41-7. PMID: 11924763

Article Published Date : Jan 01, 2002

Study Type : In Vitro Study

Additional Links

Substances : Kava Kava : CK(239) : AC(39)

Diseases : Inflammation : CK(1077) : AC(363), Oxidative Stress : CK(1945) : AC(710)

Pharmacological Actions : Anti-Inflammatory Agents : CK(1230) : AC(433), Antioxidants : CK(3653) : AC(1318), Cyclooxygenase 1 Inhibitor : CK(22) : AC(18), Cyclooxygenase 2 Inhibitors : CK(269) : AC(169)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Kava contains compunds which protect neural cells against Alzheimer associated amyloid beta-peptide induced neurotoxicity.

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Pubmed Data : Mol Pharmacol. 2008 Jun;73(6):1785-95. Epub 2008 Mar 11. PMID: 18334601

Article Published Date : Jun 01, 2008

Study Type : In Vitro Study

Additional Links

Substances : Kava Kava : CK(239) : AC(39)

Diseases : Alzheimer's Disease : CK(826) : AC(160)

Pharmacological Actions : Neuroprotective Agents : CK(962) : AC(480)

Kava has anti-inflammatory properties used in traditional Fijian medicine to treat urinary tract infections and asthma.

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Pubmed Data : Biochem Pharmacol. 2006 Apr 14;71(8):1206-18. Epub 2006 Feb 7. PMID: 16464438

Article Published Date : Apr 14, 2006

Study Type : In Vitro Study

Additional Links

Substances : Kava Kava : CK(239) : AC(39)

Diseases : Asthma : CK(918) : AC(134), Inflammation : CK(1077) : AC(363), Urinary Tract Infections : CK(338) : AC(47)

Pharmacological Actions : Anti-Inflammatory Agents : CK(1230) : AC(433), NF-kappaB Inhibitor : CK(595) : AC(401), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)

Additional Keywords : Science Confirms Tradition : CK(72) : AC(49)

Kava may contribute to ameliorating cravings in drug addiction.

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Pubmed Data : Pac Health Dialog. 2001 Sep;8(2):335-9. PMID: 12180513

Article Published Date : Sep 01, 2001

Study Type : Review

Additional Links

Substances : Kava Kava : CK(239) : AC(39)

Diseases : Cocaine Withdrawal : CK(26) : AC(7), Tobacco Addiction/Withdrawal : CK(53) : AC(6)

Safety Study: Kava does not display metabolic toxicity in a homogeneous cellular assay.

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Pubmed Data : Planta Med. 2004 Apr;70(4):289-92. PMID: 15095141

Article Published Date : Apr 01, 2004

Study Type : In Vitro Study

Additional Links

Substances : Kava Kava : CK(239) : AC(39)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Safety Study: Kava has a superior "risk-to-benefit" ratio compared to other drugs used to treat anxiety.

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Pubmed Data : Toxicol Lett. 2004 Apr 15;150(1):85-96. PMID: 15068826

Article Published Date : Apr 15, 2004

Study Type : Review

Additional Links

Substances : Kava Kava : CK(239) : AC(39)

Additional Keywords : Superiority of Natural Substances versus Drugs : CK(826) : AC(164)

Safety Study: The association between kava use and liver toxicity appears to be weak.

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Pubmed Data : J Clin Pharm Ther. 2010 Oct;35(5):545-63. PMID: 20831679

Article Published Date : Oct 01, 2010

Study Type : Review

Additional Links

Substances : Kava Kava : CK(239) : AC(39)

The consumption of Kava by Fijians may contribute to their unusually low levels of cancer.

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Pubmed Data : Phytomedicine. 2003 May;10(4):309-17. PMID: 12809361

Article Published Date : May 01, 2003

Study Type : Review

Additional Links

Substances : Kava Kava : CK(239) : AC(39)

Diseases : Cancers: All : CK(9062) : AC(2869)

Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Kava is well tolerated effective against female climacteric (menopausal) symptoms.

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Pubmed Data : Fortschr Med. 1991 Feb 10;109(4):119-22. PMID: 2029982

Article Published Date : Feb 10, 1991

Additional Links

Substances : Kava Kava : CK(239) : AC(39)

Kava may exert its favourable effects on anxiety by improving baroflex control of heart rate.

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Pubmed Data : J Psychopharmacol. 2001 Dec;15(4):283-6. PMID: 11769822

Article Published Date : Dec 01, 2001

Additional Links

Substances : Kava Kava : CK(239) : AC(39)

Kava was judged to be a safe and effective treatment for sleep disturbances associated with non-psychotic anxiety disorders.

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Pubmed Data : J Affect Disord. 2004 Feb;78(2):101-10. PMID: 14706720

Article Published Date : Feb 01, 2004

Additional Links

Substances : Kava Kava : CK(239) : AC(39)

Kava was judged to have a beneficial effect in the treatment of anxiety, tension and restlessness, without having any adverse effect on the liver.

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Pubmed Data : Phytomedicine. 2003 Nov;10(8):631-9 PMID: 14692723

Article Published Date : Nov 01, 2003

Additional Links

Substances : Kava Kava : CK(239) : AC(39)

Related Blogs

23 Natural Alternatives for Depression

Written by Pat Robinson

Kava is safe and effective in treating anxiety disorders and depression. L-tryptophan is as effective as imipramine in treating depression. Saffron may be of therapeutic benefit in the treatment of mild to moderate depression and has similar efficacy as the drug imipramine. St. John's Wort is as effective as Selective Serotoin Reuptake Inhibitors (SSRI) in the treatment of Depressive Disorder, with a greater safety rating.

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