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Lycopene
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Additional Topics Details for this Page
Article Count
- 38
Cumulative Knowledge
- 195
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Lycopene is a Sub of the following Topic
Tomato
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View the Evidence: Substances
Lycopene inhibits liver cancer cell growth.
Click here to read the entire abstract
Pubmed Data
: Biofactors. 2005 ;23(3):129-39. PMID:
16410635
Article Published Date
: Jan 01, 2005
Study Type
: Meta Analysis
Additional Links
Substances
:
Lycopene : CK(194) : AC(38)
Diseases
:
Liver Cancer : CK(1641) : AC(266)
Pharmacological Actions
:
Antioxidants : CK(3653) : AC(1318)
,
Antiproliferative : CK(1052) : AC(775)
,
Cell cycle arrest : CK(390) : AC(319)
A combination of soy, isoflavones, lycopene, silymarin and antoxidants significantly increases PSA doubling time in men with prostate cancer.
Click here to read the entire abstract
Pubmed Data
: Eur Urol. 2005 Dec;48(6):922-30; discussion 930-1. Epub 2005 Oct 17. PMID:
16263208
Article Published Date
: Dec 01, 2005
Study Type
: Human Study
Additional Links
Substances
:
Antioxidant formulas : CK(487) : AC(73)
,
Isoflavones : CK(627) : AC(124)
,
Lycopene : CK(194) : AC(38)
,
Milk Thistle : CK(226) : AC(55)
,
Soy : CK(1672) : AC(347)
Diseases
:
Prostate: PSA Doubling : CK(133) : AC(16)
,
Prostate Cancer : CK(998) : AC(288)
A formula containing calcium, vitamin D3, lycopene , astaxantin and citrus bioflavonoids reducing climacteric symptoms in menopausal women.
Click here to read the entire abstract
Pubmed Data
: Panminerva Med. 2010 Jun;52(2 Suppl 1):49-54. PMID:
20657535
Article Published Date
: Jun 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Astaxanthin : CK(353) : AC(117)
,
Bioflavonoids : CK(21) : AC(3)
,
Calcium : CK(232) : AC(35)
,
Lycopene : CK(194) : AC(38)
,
Vitamin D : CK(1682) : AC(238)
Diseases
:
Menopausal Syndrome : CK(171) : AC(27)
Carotenoids such as lycopene have a protective effect on bone health.
Click here to read the entire abstract
Pubmed Data
: J Bone Miner Res. 2009 Jun;24(6):1086-94. PMID:
19138129
Article Published Date
: Jun 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Carotenoids : CK(1055) : AC(213)
,
Lycopene : CK(194) : AC(38)
Diseases
:
Osteoporosis : CK(1171) : AC(205)
Consumption of watermelon juice increases plasma concentrations of lycopene and beta-carotene in humans.
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2003 Apr;133(4):1043-50. PMID:
12672916
Article Published Date
: Apr 01, 2003
Study Type
: Human Study
Additional Links
Substances
:
beta-Carotene : CK(217) : AC(38)
,
Carotenoids : CK(1055) : AC(213)
,
Lycopene : CK(194) : AC(38)
,
Watermelon : CK(48) : AC(9)
Diseases
:
Vitamin A Deficiency : CK(20) : AC(7)
Dietary intake of lycopene is associated with reduced pancreatic cancer risk.
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2005 Mar;135(3):592-7. PMID:
15735099
Article Published Date
: Mar 01, 2005
Study Type
: Human Study
Additional Links
Substances
:
Lycopene : CK(194) : AC(38)
,
Tomato : CK(271) : AC(47)
Diseases
:
Pancreatic Cancer : CK(530) : AC(168)
Higher concentrations of trans- and cis-lycopene may reduce the time to clearance of an oncogenic HPV infection.
Click here to read the entire abstract
Pubmed Data
: Cancer Causes Control. 2003 May;14(4):319-26. PMID:
12846362
Article Published Date
: May 01, 2003
Study Type
: Human Study
Additional Links
Substances
:
Carotenoids : CK(1055) : AC(213)
,
Lycopene : CK(194) : AC(38)
Diseases
:
Human Papillomavirus (HPV) : CK(153) : AC(22)
,
Uterine Cervical Neoplasms : CK(22) : AC(3)
Higher intake of lycopene, beta-carotene and beta-cryptoxanthin is associated to a lower risk of breast cancer among Chinese women.
Click here to read the entire abstract
Pubmed Data
: Asia Pac J Clin Nutr. 2007;16 Suppl 1:437-42. PMID:
17392146
Article Published Date
: Jan 01, 2007
Study Type
: Human Study
Additional Links
Substances
:
beta-Carotene : CK(217) : AC(38)
,
Carotenoids : CK(1055) : AC(213)
,
Cryptoxanthin : CK(36) : AC(8)
,
Lycopene : CK(194) : AC(38)
Diseases
:
Breast Cancer: Prevention : CK(525) : AC(73)
Pharmacological Actions
:
Anticarcinogenic Agents : CK(521) : AC(275)
Additional Keywords
:
Risk Reduction : CK(1909) : AC(196)
Lycopene and soy isoflavones have activity in prostate cancer patients with PSA relapse disease and may delay progression of both hormone-refractory and hormone-sensitive prostate cancer.
Click here to read the entire abstract
Pubmed Data
: J Pharm Pharmacol. 2009 Jul;61(7):961-7. PMID:
17927495
Article Published Date
: Jul 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Carotenoids : CK(1055) : AC(213)
,
Genistein : CK(450) : AC(174)
,
Isoflavones : CK(627) : AC(124)
,
Lycopene : CK(194) : AC(38)
Diseases
:
Prostate Cancer : CK(998) : AC(288)
Pharmacological Actions
:
Antineoplastic Agents : CK(877) : AC(496)
Lycopene contributes to the inhibition of LDL oxidation.
Click here to read the entire abstract
Pubmed Data
: Antioxid Redox Signal. 2000 Fall;2(3):491-506. PMID:
11229363
Article Published Date
: Sep 01, 2000
Study Type
: Human Study
Additional Links
Substances
:
Lycopene : CK(194) : AC(38)
Diseases
:
Cholesterol: Oxidation : CK(457) : AC(98)
Pharmacological Actions
:
Cardioprotective : CK(702) : AC(196)
Lycopene inhibits disease progression in patients with benign prostate hyperplasia.
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2008 Jan;138(1):49-53. PMID:
18156403
Article Published Date
: Jan 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Lycopene : CK(194) : AC(38)
Diseases
:
Prostatic Hyperplasia: Benign : CK(202) : AC(46)
Lycopene may positively modify clinical asthma outcomes.
Click here to read the entire abstract
Pubmed Data
: Free Radic Res. 2008 Jan;42(1):94-102. PMID:
18324527
Article Published Date
: Jan 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Lycopene : CK(194) : AC(38)
Diseases
:
Asthma : CK(918) : AC(134)
,
Asthma: Bronchial : CK(267) : AC(33)
Plasma levels of beta-carotene and lycopene are inversely associated with the risk of endometrial cancer in Korean women.
Click here to read the entire abstract
Pubmed Data
: Acta Obstet Gynecol Scand. 2009;88(4):434-9. PMID:
19235557
Article Published Date
: Jan 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
beta-Carotene : CK(217) : AC(38)
,
Lycopene : CK(194) : AC(38)
Diseases
:
Endometrial Cancer : CK(269) : AC(45)
Pharmacological Actions
:
Chemopreventive : CK(1528) : AC(382)
Tomato sauce supplementation reduces prostate cancer growth in men.
Click here to read the entire abstract
Pubmed Data
: Exp Biol Med (Maywood). 2002 Nov;227(10):886-93. PMID:
12424330
Article Published Date
: Nov 01, 2002
Study Type
: Human Study
Additional Links
Substances
:
Carotenoids : CK(1055) : AC(213)
,
Lycopene : CK(194) : AC(38)
,
Tomato : CK(271) : AC(47)
Diseases
:
Prostate Cancer : CK(998) : AC(288)
Pharmacological Actions
:
Anticarcinogenic Agents : CK(521) : AC(275)
,
Antioxidants : CK(3653) : AC(1318)
,
Apoptotic : CK(1489) : AC(1114)
,
Chemopreventive : CK(1528) : AC(382)
Vegetables and fruits rich in lycopene and other carotenoids may be protective against prostate cancer.
Click here to read the entire abstract
Pubmed Data
: Int J Cancer. 2005 Mar 1;113(6):1010-4. PMID:
15514967
Article Published Date
: Mar 01, 2005
Study Type
: Human Study
Additional Links
Substances
:
beta-Carotene : CK(217) : AC(38)
,
Carotenoids : CK(1055) : AC(213)
,
Cryptoxanthin : CK(36) : AC(8)
,
Lutein : CK(124) : AC(22)
,
Lycopene : CK(194) : AC(38)
,
Tomato : CK(271) : AC(47)
,
Watermelon : CK(48) : AC(9)
,
Zeaxanthin : CK(67) : AC(9)
Diseases
:
Prostate Cancer: Prevention : CK(155) : AC(16)
Pharmacological Actions
:
Chemopreventive : CK(1528) : AC(382)
Additional Keywords
:
Risk Reduction : CK(1909) : AC(196)
"Dietary lycopene and tomato extract supplementations inhibit nonalcoholic steatohepatitis-promoted hepatocarcinogenesis in rats."
Click here to read the entire abstract
Pubmed Data
: Int J Cancer. 2010 Apr 15 ;126(8):1788-96. PMID:
19551842
Article Published Date
: Apr 15, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Carotenoids : CK(1055) : AC(213)
,
Lycopene : CK(194) : AC(38)
,
Tomato : CK(271) : AC(47)
Diseases
:
Fatty Liver : CK(493) : AC(122)
,
Lipid Peroxidation : CK(403) : AC(127)
,
Oxidative Stress : CK(1945) : AC(710)
Additional Keywords
:
Plant Extracts : CK(3572) : AC(1216)
A variety of carotenoids induce reduce resistance to chemotherapy in multidrug resistant lymphoma and human breast cancer cell lines.
Click here to read the entire abstract
Pubmed Data
: In Vivo. 2004 Mar-Apr;18(2):237-44. PMID:
15113052
Article Published Date
: Mar 01, 2004
Study Type
: Animal Study
Additional Links
Substances
:
Carotenoids : CK(1055) : AC(213)
,
Lycopene : CK(194) : AC(38)
,
Paprika : CK(8) : AC(6)
,
Zeaxanthin : CK(67) : AC(9)
Diseases
:
Breast Cancer : CK(2354) : AC(621)
,
Cancers: Multi-Drug Resistant : CK(92) : AC(73)
,
Lymphoma : CK(209) : AC(69)
Pharmacological Actions
:
Apoptotic : CK(1489) : AC(1114)
,
Chemosensitizer : CK(197) : AC(159)
Additional Keywords
:
Drug-Plant-Vitamin Synergies : CK(1011) : AC(268)
Lycopene attenuates oxidative stress induced experimental cataract development.
Click here to read the entire abstract
Pubmed Data
: Nutrition. 2003 Sep;19(9):794-9. PMID:
12921892
Article Published Date
: Sep 01, 2003
Study Type
: Animal Study
Additional Links
Substances
:
Carotenoids : CK(1055) : AC(213)
,
Lycopene : CK(194) : AC(38)
Diseases
:
Cataract : CK(182) : AC(55)
Pharmacological Actions
:
Antioxidants : CK(3653) : AC(1318)
Additional Keywords
:
Sodium Selenite : CK(39) : AC(18)
Lycopene has a protective effect on gentamicin-induced oxidative stress and nephrotoxicity in rats.
Click here to read the entire abstract
Pubmed Data
: Toxicology. 2005 Nov 15;215(3):198-204. Epub 2005 Aug 26. PMID:
16125832
Article Published Date
: Nov 15, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Carotenoids : CK(1055) : AC(213)
,
Lycopene : CK(194) : AC(38)
Diseases
:
Chemotherapy-Induced Toxicity: Gentamicin : CK(22) : AC(10)
,
Chemotherapy-Induced Toxicity: Kidney : CK(8) : AC(4)
,
Kidney Damage : CK(120) : AC(42)
,
Oxidative Stress : CK(1945) : AC(710)
Pharmacological Actions
:
Antioxidants : CK(3653) : AC(1318)
,
Renoprotective : CK(191) : AC(90)
Lycopene has a synergistic effect with ciprofloxacin in the rate model of chronic bacterial prostatitis.
Click here to read the entire abstract
Pubmed Data
: Int J Antimicrob Agents. 2008 Feb;31 Suppl 1:S102-7. Epub 2007 Oct 24. PMID:
17920247
Article Published Date
: Feb 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Lycopene : CK(194) : AC(38)
Diseases
:
Prostatitis: Chronic : CK(327) : AC(11)
Additional Keywords
:
Drug-Plant-Vitamin Synergies : CK(1011) : AC(268)
Lycopene inhibits experimental metastasis of human hepatoma in athymic mice.
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2008 Mar ;138(3):538-43. PMID:
18287363
Article Published Date
: Mar 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Lycopene : CK(194) : AC(38)
Diseases
:
Cancer Metastasis : CK(272) : AC(135)
,
Liver Cancer : CK(1641) : AC(266)
,
Lung Cancer: Metastatic : CK(4) : AC(1)
Pharmacological Actions
:
Anti-metastatic : CK(192) : AC(115)
,
Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(153) : AC(71)
,
Vascular Endothelial Growth Factor A Inhibitor : CK(102) : AC(58)
Lycopene protects against cisplatin-induced kidney injury and oxidative stress in rats.
Click here to read the entire abstract
Pubmed Data
: Toxicology. 2005 Sep 1;212(2-3):116-23. PMID:
15946783
Article Published Date
: Sep 01, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Lycopene : CK(194) : AC(38)
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin : CK(172) : AC(66)
Lycopene supplementation reduces the size of spontaneously occuring leiomyoma in quail, indicating that it may have therapeutic value in the treatment of uterine leiomyoma in humans.
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2004;50(2):181-9. PMID:
15623465
Article Published Date
: Jan 01, 2004
Study Type
: Animal Study
Additional Links
Substances
:
Lycopene : CK(194) : AC(38)
Diseases
:
Leiomyoma : CK(37) : AC(16)
Saw palmetto, lycopene and selenium inhibit prostate inflammation induced in rats by partial bladder outlet obstruction.
Click here to read the entire abstract
Pubmed Data
: Urology. 2011 Jan;77(1):248.e9-16. Epub 2010 Dec 15. PMID:
21109292
Article Published Date
: Jan 01, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Carotenoids : CK(1055) : AC(213)
,
Lycopene : CK(194) : AC(38)
,
Selenium : CK(574) : AC(94)
Diseases
:
Bladder Outlet Obstruction : CK(16) : AC(4)
,
Inflammation : CK(1077) : AC(363)
,
Prostatic Hyperplasia: Benign : CK(202) : AC(46)
Pharmacological Actions
:
Anti-Inflammatory Agents : CK(1230) : AC(433)
,
Antioxidants : CK(3653) : AC(1318)
,
NF-kappaB Inhibitor : CK(595) : AC(401)
These data suggest that vegetable consumption and circulating cis-lycopene may be protective against HPV persistence.
Click here to read the entire abstract
Pubmed Data
: Cancer Epidemiol Biomarkers Prev. 2002 Sep;11(9):876-84. PMID:
12223432
Article Published Date
: Sep 01, 2002
Study Type
: Animal Study
Additional Links
Substances
:
Carotenoids : CK(1055) : AC(213)
,
Lycopene : CK(194) : AC(38)
,
Vegetables: All : CK(551) : AC(69)
Diseases
:
Human Papillomavirus (HPV) : CK(153) : AC(22)
,
Uterine Cervical Neoplasms : CK(22) : AC(3)
Pharmacological Actions
:
Chemopreventive : CK(1528) : AC(382)
Additional Keywords
:
Risk Reduction : CK(1909) : AC(196)
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