Nigella sativa

Nigella sativa

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Nigella sativa is a Sub of the following Topics

Quick Summary: Current access displays 2 out of 45 associated Diseases
NameCumulative KnowledgeArticle CountFocus Articles
Diabetes Mellitus: Type 2143Log in | Sign up
Chemical Weapon Agent Injury 122Log in | Sign up
View the Evidence: Substances

Black cumin (Nigella sativa) and Phyllanthus niruri provide symptomatic relief in the treatment of acute tonsillo-pharyngitis patients.

Pubmed Data : Int J Clin Pharmacol Ther. 2008 Jun;46(6):295-306. PMID: 18541126
Article Published Date : Jun 01, 2008
Study Type : Human Study
Additional Links
Substances : Nigella sativa : CK(117) : AC(32), Phyllanthus niruri (Stonebreaker) : CK(21) : AC(9)
Diseases : Pharyngitis : CK(30) : AC(3), Tonsillitis : CK(40) : AC(4)
Additional Keywords : Plant Extracts : CK(3401) : AC(1158)

Black cumin (Nigella sativa) has a prophylactic effect on chemical war victims.

Pubmed Data : J Altern Complement Med. 2008 Nov;14(9):1137-44. PMID: 18991514
Article Published Date : Nov 01, 2008
Study Type : Human Study
Additional Links
Substances : Nigella sativa : CK(117) : AC(32)
Diseases : Chemical Weapon Agent Injury : CK(14) : AC(4)

Black cumin alleviates symptoms of allergic rhinitis.

Pubmed Data : Am J Otolaryngol. 2010 Oct 12. Epub 2010 Oct 12. PMID: 20947211
Article Published Date : Oct 12, 2010
Study Type : Human Study
Additional Links
Substances : Nigella sativa : CK(117) : AC(32)
Diseases : Allergic Rhinitis : CK(327) : AC(40)

Black cumin possesses clinical useful anti-H. pylori activity compared to triple therapy.

Pubmed Data : Saudi J Gastroenterol. 2010 Jul-Sep;16(3):207-14. PMID: 20616418
Article Published Date : Jul 01, 2010
Study Type : Human Study
Additional Links
Substances : Nigella sativa : CK(117) : AC(32)
Diseases : Dyspepsia : CK(422) : AC(21), Helicobacter Pylori Infection : CK(305) : AC(61)
Pharmacological Actions : Anti-Bacterial Agents : CK(895) : AC(291), Anti-Ulcer Agents : CK(160) : AC(57)
Additional Keywords : Drug: Amoxicillin : CK(60) : AC(6), Drug: Omeprazole : CK(90) : AC(15), Drug-Plant-Vitamin Synergies : CK(1011) : AC(268), Natural Substances Versus Drugs : CK(1043) : AC(159), Plant Extracts : CK(3401) : AC(1158)

Black cumin seeds have significant anti-diabetic effects in type 2 diabetics.

Pubmed Data : Indian J Physiol Pharmacol. 2010 Oct-Dec;54(4):344-54. PMID: 21675032
Article Published Date : Oct 01, 2010
Study Type : Human Study
Additional Links
Substances : Nigella sativa : CK(117) : AC(32)
Diseases : A1C : CK(267) : AC(35), Diabetes: Glycation/A1C : CK(220) : AC(33), Diabetes Mellitus: Type 2 : CK(3142) : AC(328), Insulin Resistance : CK(995) : AC(212)
Pharmacological Actions : Hypoglycemic Agents : CK(554) : AC(154), Insulin Sensitizers : CK(133) : AC(28)
Additional Keywords : Beta Cell Protection : CK(52) : AC(21), Beta Cell Regeneration : CK(78) : AC(22)

The daily use of black cumin seeds for 2 months may have a blood pressure-lowering effect in patients with mild hypertension.

Pubmed Data : Braz J Med Biol Res. 2006 Apr;39(4):421-9. Epub 2006 Apr 3. PMID: 18705755
Article Published Date : Apr 01, 2006
Study Type : Human Study
Additional Links
Substances : Nigella sativa : CK(117) : AC(32)
Diseases : Hypertension : CK(2615) : AC(260)
Pharmacological Actions : Antihypertensive Agents : CK(194) : AC(38), Hypotensive : CK(372) : AC(49)
Additional Keywords : Plant Extracts : CK(3401) : AC(1158)

The water extract of black cumin seed has significant anti-epileptic activity in children.

Pubmed Data : Med Sci Monit. 2007 Dec;13(12):CR555-9. PMID: 18049435
Article Published Date : Dec 01, 2007
Study Type : Human Study
Additional Links
Substances : Nigella sativa : CK(117) : AC(32)
Diseases : Epilepsy: Childhood : CK(50) : AC(5)

A plant mixture comprising Nigella sativa, Myrrh, Gum Olibanum (Frankincense), Gum Asafoetida and Aloe lowers blood sugar by inhibiting hepatis gluconeogenesis.

Pubmed Data : Diabetes Res. 1991 Dec;18(4):163-8. PMID: 1842751
Article Published Date : Dec 01, 1991
Study Type : Animal Study
Additional Links
Substances : Aloe Vera : CK(201) : AC(44), Asafoetida : CK(8) : AC(5), Frankincense : CK(2) : AC(1), Myrrh : CK(38) : AC(13), Nigella sativa : CK(117) : AC(32)
Diseases : Diabetes Mellitus: Type 2 : CK(3142) : AC(328)
Pharmacological Actions : Gluconeogenesis Inhibitor : CK(20) : AC(14)
Additional Keywords : Plant Extracts : CK(3401) : AC(1158)

Black cumin exhibit significant antifungal activity against candidasis in mice.

Pubmed Data : Phytother Res. 2003 Feb;17(2):183-6. PMID: 12601685
Article Published Date : Feb 01, 2003
Study Type : Animal Study
Additional Links
Substances : Nigella sativa : CK(117) : AC(32)
Diseases : Candidiasis : CK(199) : AC(98), Fungal Infection : CK(241) : AC(119)
Pharmacological Actions : Antifungal Agents : CK(172) : AC(109)
Additional Keywords : Plant Extracts : CK(3401) : AC(1158)

Black cumin extract reduces the damage caused by cadmium poisoning in rats.

Pubmed Data : Biol Trace Elem Res. 2006 May;110(2):151-62. PMID: 16757843
Article Published Date : May 01, 2006
Study Type : Animal Study
Additional Links
Substances : Nigella sativa : CK(117) : AC(32)
Diseases : Cadmium Poisoning : CK(64) : AC(30)

Black Cumin improves blood lipid profiles.

Pubmed Data : Neurosci Lett. 2010 Oct 4;482(3):183-7. Epub 2010 Jun 11. PMID: 16092657
Article Published Date : Oct 04, 2010
Study Type : Animal Study
Additional Links
Substances : Nigella sativa : CK(117) : AC(32)
Diseases : Cholesterol: LDL/HDL ratio : CK(445) : AC(58), HDL: Low : CK(270) : AC(48), High Cholesterol : CK(1755) : AC(198)

Black cumin may have antidiabetic effects by increasing insulin sensitivity.

Pubmed Data : Evid Based Complement Alternat Med. 2011;2011:538671. Epub 2011 Apr 14. PMID: 21584245
Article Published Date : Jan 01, 2011
Study Type : Animal Study
Additional Links
Substances : Nigella sativa : CK(117) : AC(32)
Diseases : Diabetes Mellitus: Type 2 : CK(3142) : AC(328), Insulin Resistance : CK(995) : AC(212)
Pharmacological Actions : Insulin Sensitizers : CK(133) : AC(28)

Black cumin oil has significant inhibitory effects against colon cancer in rats, without observable side effects.

Pubmed Data : Nutr Cancer. 2003;45(2):195-202. PMID: 12881014
Article Published Date : Jan 01, 2003
Study Type : Animal Study
Additional Links
Substances : Nigella sativa : CK(117) : AC(32)
Diseases : Colon Cancer : CK(819) : AC(233)
Pharmacological Actions : Antiproliferative : CK(969) : AC(725)

Black cumin protects against chemical weapon agent induced lung injury.

Pubmed Data : Exp Lung Res. 2008 May;34(4):183-94. PMID: 18432455
Article Published Date : May 01, 2008
Study Type : Animal Study
Additional Links
Substances : Nigella sativa : CK(117) : AC(32)
Diseases : Chemical Weapon Agent Injury : CK(14) : AC(4)
Additional Keywords : Plant Extracts : CK(3401) : AC(1158)

Black cumin seed oil has significant protective activity against cytomegalovirus infection in the mouse experimental model.

Pubmed Data : Int J Immunopharmacol. 2000 Sep;22(9):729-40. PMID: 10884593
Article Published Date : Sep 01, 2000
Study Type : Animal Study
Additional Links
Substances : Nigella sativa : CK(117) : AC(32)
Diseases : Cytomegalovirus Infections : CK(85) : AC(33)
Pharmacological Actions : Antiviral Agents : CK(583) : AC(276), Interferon Inducers : CK(31) : AC(9)

Black cumin's hyperglycemic activity in the rat model of diabetes may be due to beta cell regeneration/proliferation.

Pubmed Data : Tohoku J Exp Med. 2003 Dec;201(4):213-9. PMID: 14690013
Article Published Date : Dec 01, 2003
Study Type : Animal Study
Additional Links
Substances : Nigella sativa : CK(117) : AC(32)
Diseases : Diabetes Mellitus: Type 1 : CK(1041) : AC(221)
Additional Keywords : Beta Cell Regeneration : CK(78) : AC(22)

Grape seed extract, black seed extract and curcumin ameliorate tamoxifen-induced liver injury.

Pubmed Data : Hepatogastroenterology. 2007 Jan-Feb;54(73):320-4. PMID: 21046982
Article Published Date : Jan 01, 2007
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(2890) : AC(1511), Grape Seed Extract : CK(168) : AC(57), Nigella sativa : CK(117) : AC(32)
Diseases : Chemically-Induced Liver Damage : CK(453) : AC(175), Chemotherapy-Induced Toxicity: Tamoxifen : CK(6) : AC(3), Drug-Induced Toxicity : CK(538) : AC(78)
Pharmacological Actions : Hepatoprotective : CK(534) : AC(261), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(1015) : AC(343)
Additional Keywords : Drug: Tamoxifen : CK(357) : AC(53), Plant Extracts : CK(3401) : AC(1158)

Nigella sativa (black cumin) and Syzygium aromaticum (clove) protect against aflatoxicosis in rats.

Pubmed Data : J Appl Toxicol. 2005 May-Jun;25(3):218-23. PMID: 15856529
Article Published Date : May 01, 2005
Study Type : Animal Study
Additional Links
Substances : Clove : CK(92) : AC(46), Nigella sativa : CK(117) : AC(32)
Diseases : Aflatoxicosis : CK(214) : AC(37)
Pharmacological Actions : Antioxidants : CK(3503) : AC(1292)

Nigella sativa (black cumin) has potent antiasthmatic properties.

Pubmed Data : Phytomedicine. 2010 Feb 8. Epub 2010 Feb 8. PMID: 20149611
Article Published Date : Feb 08, 2010
Study Type : Animal Study
Additional Links
Substances : Nigella sativa : CK(117) : AC(32)
Diseases : Asthma : CK(847) : AC(129)
Pharmacological Actions : Bronchodilator Agents : CK(48) : AC(11)

Nigella sativa (black cumin) protects against chronic antiretroviral therapy-associated insulin resistance in HIV-1 infected rats.

Pubmed Data : Can J Physiol Pharmacol. 2009 Apr;87(4):300-9. PMID: 19370083
Article Published Date : Apr 01, 2009
Study Type : Animal Study
Additional Links
Substances : Nigella sativa : CK(117) : AC(32)
Diseases : HIV Drug-Induced Toxicity : CK(68) : AC(13), Hyperinsulinism : CK(1175) : AC(41)
Pharmacological Actions : Antioxidants : CK(3503) : AC(1292)
Additional Keywords : Drug Side Effect Attenuation : CK(252) : AC(49)

Omega-3 fatty acids, black seed oil and curcuminoids have a therapeutic role in gastritits in an animal model.

Pubmed Data : Eur J Nutr. 2007 Oct;46(7):391-6. Epub 2007 Sep 20. PMID: 18368490
Article Published Date : Oct 01, 2007
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(2890) : AC(1511), Nigella sativa : CK(117) : AC(32), Omega-3 Fatty Acids : CK(3255) : AC(319)
Diseases : Gastritis : CK(48) : AC(8)
Additional Keywords : Plant Extracts : CK(3401) : AC(1158)

The essential oil of black cumin seed has potent analgesic and antiinflammatory activity.

Pubmed Data : Phytother Res. 2004 Mar;18(3):195-9. PMID: 15103664
Article Published Date : Mar 01, 2004
Study Type : Animal Study
Additional Links
Substances : Nigella sativa : CK(117) : AC(32)
Diseases : Inflammation : CK(994) : AC(348), Pain : CK(583) : AC(91)
Pharmacological Actions : Analgesics: Non-Narcotic : CK(25) : AC(9), Anti-Inflammatory Agents : CK(1144) : AC(420)

Thymoquinone, a compound derived from black cumin, prevents the development of gentamicin-induced acute renal toxicity in rats.

Pubmed Data : Clin Exp Pharmacol Physiol. 2007 May-Jun;34(5-6):399-405. PMID: 17439407
Article Published Date : May 01, 2007
Study Type : Animal Study
Additional Links
Substances : Nigella sativa : CK(117) : AC(32), Thymoquinone : CK(3) : AC(1)
Diseases : Chemotherapy-Induced Toxicity: Gentamicin : CK(22) : AC(10), Chemotherapy-Induced Toxicity: Kidney : CK(8) : AC(4), Kidney Damage : CK(120) : AC(42), Oxidative Stress : CK(1867) : AC(710)
Pharmacological Actions : Renoprotective : CK(185) : AC(87)

Thymoquinone, an extract of black cumin seed, attenuates arthritis in the rat model of rhematoid.

Pubmed Data : Phytother Res. 2007 Sep;21(9):895-7. PMID: 17562570
Article Published Date : Sep 01, 2007
Study Type : Animal Study
Additional Links
Substances : Nigella sativa : CK(117) : AC(32)
Diseases : Rheumatoid Arthritis : CK(413) : AC(62)
Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(1015) : AC(343)

Thymoquinone, the main constituent of Nigella sativa (black cumin) is superior to the drug fluticasone in an animal model of asthma.

Pubmed Data : J Ethnopharmacol. 2009 Oct 29;126(1):102-7. Epub 2009 Aug 8. PMID: 19711253
Article Published Date : Oct 29, 2009
Study Type : Animal Study
Additional Links
Substances : Nigella sativa : CK(117) : AC(32)
Diseases : Asthma : CK(847) : AC(129)
Pharmacological Actions : Anticholinergic : CK(4) : AC(2), Bronchodilator Agents : CK(48) : AC(11), Histamine Antagonists : CK(46) : AC(18)
Additional Keywords : Cortisone Alternatives : CK(79) : AC(12), Drug: Fluticasone : CK(22) : AC(3), Superiority of Natural Substances versus Drugs : CK(897) : AC(158)

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