Nigella sativa (aka Black Seed)

Nigella sativa (aka Black Seed)

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View the Evidence: Substances

Black cumin (Nigella sativa) and Phyllanthus niruri provide symptomatic relief in the treatment of acute tonsillo-pharyngitis patients.

Pubmed Data : Int J Clin Pharmacol Ther. 2008 Jun;46(6):295-306. PMID: 18541126
Article Published Date : Jun 01, 2008
Study Type : Human Study
Additional Links
Substances : Nigella sativa (aka Black Seed) : CK(133) : AC(34), Phyllanthus niruri (Stonebreaker) : CK(21) : AC(9)
Diseases : Pharyngitis : CK(30) : AC(3), Tonsillitis : CK(40) : AC(4)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Black cumin (Nigella sativa) has a prophylactic effect on chemical war victims.

Pubmed Data : J Altern Complement Med. 2008 Nov;14(9):1137-44. PMID: 18991514
Article Published Date : Nov 01, 2008
Study Type : Human Study
Additional Links
Substances : Nigella sativa (aka Black Seed) : CK(133) : AC(34)
Diseases : Chemical Weapon Agent Injury : CK(14) : AC(4)

Black cumin (Nigella sativa) is effective in long-term treatment of opioid dependence.

Pubmed Data : J Ayub Med Coll Abbottabad. 2008 Apr-Jun;20(2):118-24. PMID: 19385474
Article Published Date : Apr 01, 2008
Study Type : Human Study
Additional Links
Substances : Nigella sativa (aka Black Seed) : CK(133) : AC(34)
Diseases : Opiate Addiction/Withdrawal : CK(64) : AC(14)

Black cumin alleviates symptoms of allergic rhinitis.

Pubmed Data : Am J Otolaryngol. 2010 Oct 12. Epub 2010 Oct 12. PMID: 20947211
Article Published Date : Oct 12, 2010
Study Type : Human Study
Additional Links
Substances : Nigella sativa (aka Black Seed) : CK(133) : AC(34)
Diseases : Allergic Rhinitis : CK(318) : AC(40)

Black cumin possesses clinical useful anti-H. pylori activity compared to triple therapy.

Pubmed Data : Saudi J Gastroenterol. 2010 Jul-Sep;16(3):207-14. PMID: 20616418
Article Published Date : Jul 01, 2010
Study Type : Human Study
Additional Links
Substances : Nigella sativa (aka Black Seed) : CK(133) : AC(34)
Diseases : Dyspepsia : CK(422) : AC(21), Helicobacter Pylori Infection : CK(305) : AC(61)
Pharmacological Actions : Anti-Bacterial Agents : CK(970) : AC(316), Anti-Ulcer Agents : CK(162) : AC(57)
Additional Keywords : Drug: Amoxicillin : CK(60) : AC(6), Drug: Omeprazole : CK(90) : AC(15), Drug-Plant-Vitamin Synergies : CK(1011) : AC(268), Natural Substances Versus Drugs : CK(988) : AC(165), Plant Extracts : CK(3572) : AC(1216)

Black cumin seeds have significant anti-diabetic effects in type 2 diabetics.

Pubmed Data : Indian J Physiol Pharmacol. 2010 Oct-Dec;54(4):344-54. PMID: 21675032
Article Published Date : Oct 01, 2010
Study Type : Human Study
Additional Links
Substances : Nigella sativa (aka Black Seed) : CK(133) : AC(34)
Diseases : A1C : CK(253) : AC(35), Diabetes: Glycation/A1C : CK(186) : AC(33), Diabetes Mellitus: Type 2 : CK(3429) : AC(341), Insulin Resistance : CK(1034) : AC(221)
Pharmacological Actions : Hypoglycemic Agents : CK(563) : AC(156), Insulin Sensitizers : CK(167) : AC(36)
Additional Keywords : Beta Cell Protection : CK(53) : AC(22), Beta Cell Regeneration : CK(60) : AC(24)

Nigella sativa (black cumin) has potent antiasthmatic properties.

Pubmed Data : Phytomedicine. 2010 Feb 8. Epub 2010 Feb 8. PMID: 20149611
Article Published Date : Feb 08, 2010
Study Type : Human Study
Additional Links
Substances : Nigella sativa (aka Black Seed) : CK(133) : AC(34)
Diseases : Asthma : CK(918) : AC(134)
Pharmacological Actions : Bronchodilator Agents : CK(56) : AC(12)

The daily use of black cumin seeds for 2 months may have a blood pressure-lowering effect in patients with mild hypertension.

Pubmed Data : Braz J Med Biol Res. 2006 Apr;39(4):421-9. Epub 2006 Apr 3. PMID: 18705755
Article Published Date : Apr 01, 2006
Study Type : Human Study
Additional Links
Substances : Nigella sativa (aka Black Seed) : CK(133) : AC(34)
Diseases : Hypertension : CK(2783) : AC(271)
Pharmacological Actions : Antihypertensive Agents : CK(196) : AC(38), Hypotensive : CK(383) : AC(53)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

The water extract of black cumin seed has significant anti-epileptic activity in children.

Pubmed Data : Med Sci Monit. 2007 Dec;13(12):CR555-9. PMID: 18049435
Article Published Date : Dec 01, 2007
Study Type : Human Study
Additional Links
Substances : Nigella sativa (aka Black Seed) : CK(133) : AC(34)
Diseases : Epilepsy: Childhood : CK(50) : AC(5)

"Nigella sativa (black cumin) seed extract alleviates symptoms of allergic diarrhea in mice, involving opioid receptors."

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2012 ;7(6):e39841. Epub 2012 Jun 29. PMID: 22768141
Article Published Date : Dec 31, 2011
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed) : CK(133) : AC(34)
Diseases : Diarrhea : CK(544) : AC(72), Food Allergies : CK(420) : AC(57)
Additional Keywords : Phytotherapy : CK(177) : AC(27), Plant Extracts : CK(3572) : AC(1216)

A plant mixture comprising Nigella sativa, Myrrh, Gum Olibanum (Frankincense), Gum Asafoetida and Aloe lowers blood sugar by inhibiting hepatis gluconeogenesis.

Pubmed Data : Diabetes Res. 1991 Dec;18(4):163-8. PMID: 1842751
Article Published Date : Dec 01, 1991
Study Type : Animal Study
Additional Links
Substances : Aloe Vera : CK(201) : AC(44), Asafoetida : CK(8) : AC(5), Frankincense : CK(22) : AC(1), Myrrh : CK(37) : AC(13), Nigella sativa (aka Black Seed) : CK(133) : AC(34)
Diseases : Diabetes Mellitus: Type 2 : CK(3429) : AC(341)
Pharmacological Actions : Gluconeogenesis Inhibitor : CK(20) : AC(14)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Black cumin exhibit significant antifungal activity against candidasis in mice.

Pubmed Data : Phytother Res. 2003 Feb;17(2):183-6. PMID: 12601685
Article Published Date : Feb 01, 2003
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed) : CK(133) : AC(34)
Diseases : Candidiasis : CK(199) : AC(98), Fungal Infection : CK(243) : AC(119)
Pharmacological Actions : Antifungal Agents : CK(178) : AC(111)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Black cumin extract reduces the damage caused by cadmium poisoning in rats.

Pubmed Data : Biol Trace Elem Res. 2006 May;110(2):151-62. PMID: 16757843
Article Published Date : May 01, 2006
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed) : CK(133) : AC(34)
Diseases : Cadmium Poisoning : CK(64) : AC(30)

Black Cumin improves blood lipid profiles.

Pubmed Data : Neurosci Lett. 2010 Oct 4;482(3):183-7. Epub 2010 Jun 11. PMID: 16092657
Article Published Date : Oct 04, 2010
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed) : CK(133) : AC(34)
Diseases : Cholesterol: LDL/HDL ratio : CK(432) : AC(58), HDL: Low : CK(255) : AC(45), High Cholesterol : CK(1718) : AC(198)

Black cumin may have antidiabetic effects by increasing insulin sensitivity.

Pubmed Data : Evid Based Complement Alternat Med. 2011;2011:538671. Epub 2011 Apr 14. PMID: 21584245
Article Published Date : Jan 01, 2011
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed) : CK(133) : AC(34)
Diseases : Diabetes Mellitus: Type 2 : CK(3429) : AC(341), Insulin Resistance : CK(1034) : AC(221)
Pharmacological Actions : Insulin Sensitizers : CK(167) : AC(36)

Black cumin protects against chemical weapon agent induced lung injury.

Pubmed Data : Exp Lung Res. 2008 May;34(4):183-94. PMID: 18432455
Article Published Date : May 01, 2008
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed) : CK(133) : AC(34)
Diseases : Chemical Weapon Agent Injury : CK(14) : AC(4)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Black cumin seed oil has significant protective activity against cytomegalovirus infection in the mouse experimental model.

Pubmed Data : Int J Immunopharmacol. 2000 Sep;22(9):729-40. PMID: 10884593
Article Published Date : Sep 01, 2000
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed) : CK(133) : AC(34)
Diseases : Cytomegalovirus Infections : CK(85) : AC(33)
Pharmacological Actions : Antiviral Agents : CK(613) : AC(280), Interferon Inducers : CK(31) : AC(9)

Black cumin's hyperglycemic activity in the rat model of diabetes may be due to beta cell regeneration/proliferation.

Pubmed Data : Tohoku J Exp Med. 2003 Dec;201(4):213-9. PMID: 14690013
Article Published Date : Dec 01, 2003
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed) : CK(133) : AC(34)
Diseases : Diabetes Mellitus: Type 1 : CK(1107) : AC(218)
Additional Keywords : Beta Cell Regeneration : CK(60) : AC(24)

Black seed oil has significant inhibitory effects against colon cancer in rats, without observable side effects.

Pubmed Data : Nutr Cancer. 2003;45(2):195-202. PMID: 12881014
Article Published Date : Jan 01, 2003
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed) : CK(133) : AC(34)
Diseases : Colon Cancer : CK(895) : AC(233)
Pharmacological Actions : Antiproliferative : CK(1052) : AC(775)

Grape seed extract, black seed extract and curcumin ameliorate tamoxifen-induced liver injury.

Pubmed Data : Hepatogastroenterology. 2007 Jan-Feb;54(73):320-4. PMID: 21046982
Article Published Date : Jan 01, 2007
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(2910) : AC(1482), Grape Seed Extract : CK(168) : AC(57), Nigella sativa (aka Black Seed) : CK(133) : AC(34)
Diseases : Chemically-Induced Liver Damage : CK(475) : AC(175), Chemotherapy-Induced Toxicity: Tamoxifen : CK(6) : AC(3), Drug-Induced Toxicity : CK(560) : AC(78)
Pharmacological Actions : Hepatoprotective : CK(557) : AC(272), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)
Additional Keywords : Drug: Tamoxifen : CK(380) : AC(57), Plant Extracts : CK(3572) : AC(1216)

Nigella sativa (black cumin) and Syzygium aromaticum (clove) protect against aflatoxicosis in rats.

Pubmed Data : J Appl Toxicol. 2005 May-Jun;25(3):218-23. PMID: 15856529
Article Published Date : May 01, 2005
Study Type : Animal Study
Additional Links
Substances : Clove : CK(92) : AC(46), Nigella sativa (aka Black Seed) : CK(133) : AC(34)
Diseases : Aflatoxicosis : CK(214) : AC(37)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

Nigella sativa (black cumin) protects against chronic antiretroviral therapy-associated insulin resistance in HIV-1 infected rats.

Pubmed Data : Can J Physiol Pharmacol. 2009 Apr;87(4):300-9. PMID: 19370083
Article Published Date : Apr 01, 2009
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed) : CK(133) : AC(34)
Diseases : HIV Drug-Induced Toxicity : CK(68) : AC(13), Hyperinsulinism : CK(1182) : AC(41)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)
Additional Keywords : Drug Side Effect Attenuation : CK(252) : AC(49)

Omega-3 fatty acids, black seed oil and curcuminoids have a therapeutic role in gastritits in an animal model.

Pubmed Data : Eur J Nutr. 2007 Oct;46(7):391-6. Epub 2007 Sep 20. PMID: 18368490
Article Published Date : Oct 01, 2007
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(2910) : AC(1482), Nigella sativa (aka Black Seed) : CK(133) : AC(34), Omega-3 Fatty Acids : CK(3333) : AC(319)
Diseases : Gastritis : CK(291) : AC(8)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

The essential oil of black cumin seed has potent analgesic and antiinflammatory activity.

Pubmed Data : Phytother Res. 2004 Mar;18(3):195-9. PMID: 15103664
Article Published Date : Mar 01, 2004
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed) : CK(133) : AC(34)
Diseases : Inflammation : CK(1077) : AC(363), Pain : CK(616) : AC(91)
Pharmacological Actions : Analgesics: Non-Narcotic : CK(25) : AC(9), Anti-Inflammatory Agents : CK(1230) : AC(433)

Thymoquinone, a compound derived from black cumin, prevents the development of gentamicin-induced acute renal toxicity in rats.

Pubmed Data : Clin Exp Pharmacol Physiol. 2007 May-Jun;34(5-6):399-405. PMID: 17439407
Article Published Date : May 01, 2007
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed) : CK(133) : AC(34), Thymoquinone : CK(3) : AC(1)
Diseases : Chemotherapy-Induced Toxicity: Gentamicin : CK(22) : AC(10), Chemotherapy-Induced Toxicity: Kidney : CK(8) : AC(4), Kidney Damage : CK(120) : AC(42), Oxidative Stress : CK(1945) : AC(710)
Pharmacological Actions : Renoprotective : CK(191) : AC(90)

Related Blogs

Black Seed - 'The Remedy For Everything But Death'
Written by Sayer Ji, Founder
This humble, but immensely powerful seed, kills MRSA, heals the chemical weapon poisoned body, stimulates regeneration of the dying beta cells within the diabetic's pancreas, and yet too few even know it exists.

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