Olive Oil

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60 Diseases Researched for Olive Oil
NameACCKFocus
Oxidative Stress738Locked
Cholesterol: Oxidation422Locked
Atherosclerosis220Locked
Cholesterol: High220Locked
Insulin Resistance220Locked
Breast Cancer413Locked
Inflammation211Locked
Air Pollution Linked Toxicity110Locked
Anal Fissure110Locked
Breast Cancer: Prevention110Locked
C-Reactive Protein110Locked
Cardiovascular Diseases110Locked
Diabetes Mellitus: Type 1110Locked
Fatty Liver110Locked
HDL: Low110Locked
HIV110Locked
HIV Drug-Induced Toxicity 110Locked
HIV Infections110Locked
High Cholesterol110Locked
Hyperglycemia110Locked
Hypertension110Locked
Insect Bites: Repellent110Locked
Multiple Sclerosis110Locked
Myocardial Infarction110Locked
Obesity110Locked
Prediabetes110Locked
Stroke110Locked
Weight Problems110Locked
Alzheimer's Disease38Locked
Glioblastoma15Locked
Acrylamide-induced toxicity24Locked
Aluminum Toxicity 24Locked
Osteoporosis24Locked
Colon Cancer23Locked
Arteriosclerosis22Locked
Brain Inflammation 12Locked
Cervical Cancer12Locked
Chemically-Induced Liver Damage12Locked
Cognitive Decline/Dysfunction12Locked
Colitis12Locked
Endometrial Cancer12Locked
High Fat Diet12Locked
Infertility: Male12Locked
Learning disorders12Locked
Lipid Peroxidation12Locked
Memory Disorders12Locked
Nonverbal Learning Disorder12Locked
Ovarian Cancer12Locked
Rheumatoid Arthritis12Locked
Stroke: Attenuation/Recovery 12Locked
Stroke: Ischemic12Locked
Systemic Lupus Erythematosus12Locked
Ulcerative Colitis12Locked
Breast Cancer: HER-2 Overexpressed11Locked
Breast Cancer: Triple Negative 11Locked
Chronic Disease11Locked
Endothelial Dysfunction11Locked
Melanoma11Locked
Neurodegenerative Diseases11Locked
Nonalcoholic fatty liver disease (NAFLD) 11Locked
39 Pharmacological Actions Researched for Olive Oil
NameACCKFocus
Antioxidants1143Locked
Anti-Inflammatory Agents931Locked
Anticholesteremic Agents330Locked
Hypoglycemic Agents330Locked
NF-kappaB Inhibitor317Locked
Chemopreventive313Locked
Interleukin-6 Downregulation212Locked
Neuroprotective Agents511Locked
Anti-atherogenic110Locked
Anticarcinogenic Agents110Locked
Antihypertensive Agents110Locked
Glucagon Like peptide 1 (GLP-1) Up-regulation110Locked
Glucose transporter-2 (GLUT2) expression up-regulation110Locked
Hypolipidemic110Locked
Immunomodulatory110Locked
Insulin Sensitizers110Locked
Vasoprotective110Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor27Locked
Malondialdehyde Down-regulation36Locked
Antiproliferative 34Locked
Cardioprotective24Locked
Bone Density Conservation Agents12Locked
Genoprotective12Locked
Heme oxygenase-1 up-regulation12Locked
Hepatoprotective12Locked
Matrix metalloproteinase-3 (MMP-3) inhibitor12Locked
Nrf2 activation12Locked
Osteoprotective 12Locked
Prostaglandin PGE2 downregulation12Locked
Renoprotective12Locked
AKT-mammalian target of rapamycin (mTOR) pathway inhibitor11Locked
Anti-Tumor11Locked
Anti-metastatic11Locked
Apoptotic11Locked
Bcl-2 protein down-regulation11Locked
Cytotoxic11Locked
Intercellular adhesion molecule 3 down-regulation11Locked
Vascular Cell Adhesion Molecule-1 Inhibitor 11Locked
Vasodilator Agents11Locked

View the Evidence:
64 Abstracts with Olive Oil Research

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A MeDiet enriched with either virgin olive oil or nuts enhances the plasma antioxidant capabilities and decreases xanthine oxidase.Sep 06, 2016

Pubmed Data : Mol Nutr Food Res. 2016 Sep 7. Epub 2016 Sep 7. PMID: 27600061
Article Published Date : Sep 06, 2016
Study Type : Human Study
Additional Links
Substances : Nuts, Olive Oil
Diseases : Metabolic Syndrome X
Therapeutic Actions : Dietary Modification: Mediterranean Diet
Pharmacological Actions : Antioxidants, Xanthine oxidase inhibitor
[+]

A Mediterranean diet (that emphasizes olive oil, fiber, fruits, vegetables, fish and alcohol and reduces meat/meat products) can be an effective measure for reducing the risk of myocardial infarction.Apr 01, 2005

Pubmed Data : Antiviral Res. 2005 Apr;66(1):9-12. PMID: 12242583
Article Published Date : Apr 01, 2005
Study Type : Human Study
Additional Links
Substances : Alcohol , Fiber, Fish, Fruit: All, Olive, Olive Oil, Vegetables: All
Diseases : Myocardial Infarction
Therapeutic Actions : Dietary Modification: Mediterranean Diet
Additional Keywords : Risk Reduction
[+]

A Mediterranean diet rich in olive oil may have a protective role in multiple sclerosis. Jun 01, 2009

Pubmed Data : Coll Antropol. 2009 Jun;33(2):539-45. PMID: 19662776
Article Published Date : Jun 01, 2009
Study Type : Human Study
Additional Links
Substances : Olive, Olive Oil
Diseases : Multiple Sclerosis
Therapeutic Actions : Dietary Modification: Mediterranean Diet
[+]

A Mediterranean diet rich in virgin olive oil is associated with high plasma antioxidant capacity and reduced body weight gain.Dec 01, 2009

Pubmed Data : Eur J Clin Nutr. 2009 Dec;63(12):1387-93. Epub 2009 Aug 26. PMID: 19707219
Article Published Date : Dec 01, 2009
Study Type : Human Study
Additional Links
Substances : Olive, Olive Oil
Diseases : Oxidative Stress, Weight Problems
Therapeutic Actions : Dietary Modification: Mediterranean Diet
[+]

A Mediterranean diet supplemented with olive oil or nuts is associated with improved cognitive function in older populations. Jun 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : JAMA Intern Med. 2015 Jul ;175(7):1094-103. PMID: 25961184
Article Published Date : Jun 30, 2015
Study Type : Human Study
Additional Links
Substances : Nuts, Olive Oil
Diseases : Aging, Cognitive Decline/Dysfunction
Pharmacological Actions : Neuroprotective Agents
[+]

A mixture of honey, olive oil and beeswax is safe and effective for hemorrhoids and anal fissure.Feb 02, 2006

Pubmed Data : ScientificWorldJournal. 2006 Feb 2;6:1998-2005. PMID: 17369999
Article Published Date : Feb 02, 2006
Study Type : Human Study
Additional Links
Substances : Beeswax, Honey, Olive, Olive Oil
Diseases : Anal Fissure
[+]

Consumption of olive oil polyphenols decreased plasma LDL concentrations and LDL atherogenicity in healthy young men.Jun 30, 2015

Pubmed Data : J Nutr. 2015 Jul 1. Epub 2015 Jul 1. PMID: 26136585
Article Published Date : Jun 30, 2015
Study Type : Human Study
Additional Links
Substances : Olive Oil, Polyphenols
Diseases : Atherosclerosis, Cholesterol: Oxidation, High Cholesterol, Oxidative Stress
Pharmacological Actions : Anticholesteremic Agents, Antioxidants
Additional Keywords : Dietary Modification, Risk Reduction
[+]

Consumption of olive oil-rich diet tended to increase omentin and adiponectin in comparison with the usual diet.Dec 07, 2016

Pubmed Data : Int J Food Sci Nutr. 2016 Dec 8:1-9. Epub 2016 Dec 8. PMID: 27931137
Article Published Date : Dec 07, 2016
Study Type : Human Study
Additional Links
Substances : Olive Oil
Diseases : Adiponectin: Low Levels, Overweight
Pharmacological Actions : Adiponectin upregulation
[+]

EVOO has beneficial effect on post-prandial glycemic and LDL-C profiles.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Diabetes. 2015 ;5:e172. Epub 2015 Jul 20. PMID: 26192450
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Olive Oil
Diseases : Cardiovascular Diseases, Cholesterol: High, Hyperglycemia
Pharmacological Actions : Anticholesteremic Agents, Hypoglycemic Agents
[+]

Extra virgin olive oil consumption could lower high-sensitivity C-reactive protein in patients on antiretroviral treatments.Dec 31, 2014

Pubmed Data : Med Sci Monit. 2015 ;21:2406-13. Epub 2015 Aug 16. PMID: 26280823
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Olive Oil
Diseases : Atherosclerosis, C-Reactive Protein, HIV, HIV Drug-Induced Toxicity , HIV Infections, Inflammation
Pharmacological Actions : Anti-atherogenic, Anti-Inflammatory Agents
[+]

Extra virgin olive oil improves post-prandial glycemic and lipid profile in patients with impaired fasting glucose.May 27, 2016

Pubmed Data : Clin Nutr. 2016 May 28. Epub 2016 May 28. PMID: 27289163
Article Published Date : May 27, 2016
Study Type : Human Study
Additional Links
Substances : Olive Oil
Diseases : Prediabetes
Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic
Additional Keywords : Risk Reduction
[+]

Extra-virgin olive oil might improve metabolic control and circulating inflammatory adipokines profile in overweight T2D patients.Jun 24, 2016

Pubmed Data : J Endocrinol Invest. 2016 Jun 25. Epub 2016 Jun 25. PMID: 27344308
Article Published Date : Jun 24, 2016
Study Type : Human Study
Additional Links
Substances : Olive Oil
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Anti-Inflammatory Agents, Hypoglycemic Agents
[+]

Extra-virgin olive oil reduces the glycemic response to a high-glycemic index meal in patients with type 1 diabetes.Feb 08, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Diabetes Care. 2016 Feb 9. Epub 2016 Feb 9. PMID: 26861923
Article Published Date : Feb 08, 2016
Study Type : Human Study
Additional Links
Substances : Olive Oil
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Hypoglycemic Agents
[+]

Food fried in extra-virgin olive oil improves postprandial insulin response in obese, insulin-resistant women.Dec 13, 2010

Pubmed Data : J Med Food. 2010 Dec 13. Epub 2010 Dec 13. PMID: 21142948
Article Published Date : Dec 13, 2010
Study Type : Human Study
Additional Links
Substances : Olive, Olive Oil
Diseases : Insulin Resistance, Obesity
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High olive oil consumption had a protective role on the risk of stroke in older subjects.Aug 01, 2011

Pubmed Data : Neurology. 2011 Aug 2 ;77(5):418-25. Epub 2011 Jun 15. PMID: 21676914
Article Published Date : Aug 01, 2011
Study Type : Human Study
Additional Links
Substances : Olive Oil
Diseases : Stroke
Additional Keywords : Risk Reduction
[+]

Higher olive oil intake is associated with a modestly lower risk of T2D in women.Jul 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Clin Nutr. 2015 Aug ;102(2):479-86. Epub 2015 Jul 8. PMID: 26156740
Article Published Date : Jul 31, 2015
Study Type : Human Study
Additional Links
Substances : Olive Oil
Diseases : Diabetes Mellitus: Type 2: Prevention
Additional Keywords : Risk Reduction
[+]

Increased dietary ω-3 polyunsaturated fatty acids and extra virgin olive oil have beneficial synergistic effects on lipid metabolism and oxidative stress in patients with MetS.May 31, 2015

Pubmed Data : Nutrition. 2015 Jun ;31(6):834-40. Epub 2015 Jan 3. PMID: 25933490
Article Published Date : May 31, 2015
Study Type : Human Study
Additional Links
Substances : Fish Oil, Olive Oil
Diseases : Cholesterol: High, Oxidative Stress
Pharmacological Actions : Anticholesteremic Agents
Additional Keywords : Natural Substance Synergy
[+]

Olive oil consumption has an ameliorative effect in non-alcoholic fatty liver disease.Apr 21, 2009

Pubmed Data : World J Gastroenterol. 2009 Apr 21;15(15):1809-15. PMID: 19370776
Article Published Date : Apr 21, 2009
Study Type : Human Study
Additional Links
Substances : Olive Oil
Diseases : Fatty Liver, Insulin Resistance
Therapeutic Actions : Dietary Modification: Mediterranean Diet
Pharmacological Actions : Antioxidants, Glucagon Like peptide 1 (GLP-1) Up-regulation, Glucose transporter-2 (GLUT2) expression up-regulation, Insulin Sensitizers, Interleukin-6 Downregulation, NF-kappaB Inhibitor
[+]

Olive oil may be a valuable therapeutic support in Fibromyalgia.Jul 20, 2016

Pubmed Data : Biol Res Nurs. 2016 Jul 21. Epub 2016 Jul 21. PMID: 27443526
Article Published Date : Jul 20, 2016
Study Type : Human Study
Additional Links
Substances : Olive Oil
Diseases : DNA damage, Fibromyalgia, Lipid Peroxidation, Oxidative Stress
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation
[+]

Olive oil supplementation may be an efficacious intervention to protect against vascular effects of exposure to air pollution.Oct 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Health Perspect. 2015 Nov ;123(11):1173-9. Epub 2015 May 1. PMID: 25933197
Article Published Date : Oct 31, 2015
Study Type : Human Study
Additional Links
Substances : Olive Oil
Diseases : Air Pollution Linked Toxicity
Pharmacological Actions : Vasoprotective
[+]

Substituting EVOO for oils used in a typical American diet may have both cardio-metabolic and immunologic health benefits as indicated by reduced systolic blood pressure.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Metab (Lond). 2015 ;12:28. Epub 2015 Aug 7. PMID: 26251666
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Olive Oil
Diseases : Hypertension
Pharmacological Actions : Antihypertensive Agents, Immunomodulatory
[+]

The consumption of vegetables and fruits are inversely, significantly and strongly associated with breast cancer risk. There also is evidence that olive oil consumption may reduce the risk of breast cancer. Jan 18, 1995

Pubmed Data : J Natl Cancer Inst. 1995 Jan 18;87(2):110-6. PMID: 7503842
Article Published Date : Jan 18, 1995
Study Type : Human Study
Additional Links
Substances : Fruit: All, Olive, Olive Oil, Vegetables: All
Diseases : Breast Cancer: Prevention
Additional Keywords : Inverse Relationship, Risk Reduction
[+]

The results of the PREDIMED trial suggest a beneficial effect of a MeDiet supplemented with EVOO in the primary prevention of breast cancer. Sep 13, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : JAMA Intern Med. 2015 Sep 14:1-9. Epub 2015 Sep 14. PMID: 26365989
Article Published Date : Sep 13, 2015
Study Type : Human Study
Additional Links
Substances : Olive Oil
Diseases : Breast Cancer
Therapeutic Actions : Dietary Modification: Mediterranean Diet
Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive
Additional Keywords : Risk Reduction
[+]

These results provide for the first time a first-level evidence of an enhancement in HDL function by polyphenol-rich olive oil.Aug 31, 2014

Pubmed Data : Arterioscler Thromb Vasc Biol. 2014 Sep ;34(9):2115-9. Epub 2014 Jul 24. PMID: 25060792
Article Published Date : Aug 31, 2014
Study Type : Human Study
Additional Links
Substances : Olive Oil, Polyphenols
Diseases : Cholesterol: Oxidation, HDL: Low
Pharmacological Actions : Antioxidants
[+]

Ylang ylang oil and lemongrass oil are suitable to be used as green repellents for mosquito control, which are safe for humans, domestic animals and environmental friendly.Jan 31, 2015

Pubmed Data : Acta Trop. 2015 Feb ;142:127-30. Epub 2014 Nov 28. PMID: 25438256
Article Published Date : Jan 31, 2015
Study Type : Human Study
Additional Links
Substances : Coconut Oil, Lemongrass: Essential Oil, Olive Oil, Ylang-ylang
Diseases : Insect Bites: Repellent
[+]

Findings from in vivo and in vitro studies provide further support for the protective effect of Oleocanthal against the progression of Alzheimer's Disease.Sep 15, 2015

Pubmed Data : ACS Chem Neurosci. 2015 Sep 16. Epub 2015 Sep 16. PMID: 26348065
Article Published Date : Sep 15, 2015
Study Type : Animal Study, Human In Vitro
Additional Links
Substances : Oleocanthal, Olive Oil
Diseases : Alzheimer's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Olive oil compounds inhibit the effect of the chronic inflammatory microenvironment on glioblastoma progression.Aug 31, 2015

Pubmed Data : J Nutr Biochem. 2015 Sep 1. Epub 2015 Sep 1. PMID: 26410343
Article Published Date : Aug 31, 2015
Study Type : Human In Vitro
Additional Links
Substances : Olive Oil
Diseases : Glioblastoma
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

"Dietary unsaponificable fraction from extra virgin olive oil supplementation attenuates acute ulcerative colitis in mice."Dec 09, 2012

Pubmed Data : Eur J Pharm Sci. 2012 Dec 10. Epub 2012 Dec 10. PMID: 23238173
Article Published Date : Dec 09, 2012
Study Type : Animal Study
Additional Links
Substances : Olive Oil, Unsaponifiables
Diseases : Ulcerative Colitis
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A sea buckthorn and olive oil mixture could be considered as an alternative dressing for full-thickness burns.Jun 30, 2014

Pubmed Data : Adv Skin Wound Care. 2014 Jul ;27(7):317-23. PMID: 24932952
Article Published Date : Jun 30, 2014
Study Type : Animal Study
Additional Links
Substances : Olive Oil, Sea buckthorn
Diseases : Burns, Wound Healing
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Natural Substance Synergy
[+]

Active components in Nigella sativa and Olive oil may prove useful in treating impaired cognition.Nov 20, 2016

Pubmed Data : Nutr Neurosci. 2016 Nov 21:1-10. Epub 2016 Nov 21. PMID: 27868798
Article Published Date : Nov 20, 2016
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed), Olive Oil
Diseases : Cognitive Decline/Dysfunction
Pharmacological Actions : Neuroprotective Agents
[+]

Combined treatment of hydroxytyrosol, oleic acid and n-3 fatty acids exhibit huge therapeutic benefits in colitis.Mar 22, 2016

Pubmed Data : Int Immunopharmacol. 2016 Mar 23 ;35:29-42. Epub 2016 Mar 23. PMID: 27016717
Article Published Date : Mar 22, 2016
Study Type : Animal Study
Additional Links
Substances : Hydroxytyrosol, Oleic acid, Olive Oil, Omega-3 Fatty Acids
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Dietary olive oil effect improves the antioxidant status and fatty acid profile in the erythrocyte of 2,4-D- exposed rats.Jan 01, 2010

Pubmed Data : Lipids Health Dis. 2010 ;9:89. Epub 2010 Aug 25. PMID: 20738870
Article Published Date : Jan 01, 2010
Study Type : Animal Study
Additional Links
Substances : Olive Oil
Diseases : Lipid Peroxidation, Oxidative Stress
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation
[+]

Extra virgin olive oil can decrease the frequency of cardiac complications and genotoxicity induced by co-exposure to aluminum and acrylamide.Sep 01, 2015

Pubmed Data : Food Funct. 2015 Sep 2 ;6(9):3098-108. PMID: 26215160
Article Published Date : Sep 01, 2015
Study Type : Animal Study
Additional Links
Substances : Olive Oil
Diseases : Acrylamide-induced toxicity, Aluminum Toxicity
Pharmacological Actions : Antioxidants, Cardioprotective, Genoprotective
Problem Substances : Acrylamide , Aluminum
Adverse Pharmacological Actions : Genotoxic
[+]

Extra virgin olive oil improves learning and memory in mice. Sep 28, 2011

Pubmed Data : J Alzheimers Dis. 2011 Sep 28. Epub 2011 Sep 28. PMID: 21955812
Article Published Date : Sep 28, 2011
Study Type : Animal Study
Additional Links
Substances : Olive Oil
Diseases : Cognitive Decline/Dysfunction, Learning disorders, Memory Disorders, Nonverbal Learning Disorder
[+]

Extra virgin olive oil is a beneficial functional food exerting a preventive/palliative role in the management of systemic lupus erythematosus.Dec 31, 2015

Pubmed Data : J Nutr Biochem. 2016 Jan ;27:278-88. Epub 2015 Oct 29. PMID: 26525667
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Olive Oil
Diseases : Systemic Lupus Erythematosus
Pharmacological Actions : Anti-Inflammatory Agents, Matrix metalloproteinase-3 (MMP-3) inhibitor, NF-kappaB Inhibitor, Prostaglandin PGE2 downregulation, Renoprotective
[+]

Extra virgin olive oil is effective in ameliorating the harmful effects of genetically modified soya bean on the male reproductive system which may protect or restore fertility.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Nutr Res. 2015 ;59:27758. Epub 2015 Sep 18. PMID: 26388519
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Olive Oil
Diseases : Infertility: Male, Oxidative Stress
Pharmacological Actions : Antioxidants
Problem Substances : Soy
[+]

Extra virgin olive oil may have a beneficial role in decreasing the liver damage induced by both aluminum and acrylamide.Mar 31, 2015

Pubmed Data : Food Funct. 2015 Apr ;6(4):1126-35. PMID: 25690328
Article Published Date : Mar 31, 2015
Study Type : Animal Study
Additional Links
Substances : Olive Oil
Diseases : Acrylamide-induced toxicity, Aluminum Toxicity , Chemically-Induced Liver Damage
Pharmacological Actions : Hepatoprotective
Problem Substances : Acrylamide , Aluminum
[+]

Extra virgin olive oil might provide a basis for developing a new dietary supplementation strategy in order to prevent lung tissue damage.Jul 03, 2016

Pubmed Data : Environ Sci Pollut Res Int. 2016 Jul 4. Epub 2016 Jul 4. PMID: 27378219
Article Published Date : Jul 03, 2016
Study Type : Animal Study
Additional Links
Substances : Olive Oil
Diseases : DNA damage, Oxidative Stress
Pharmacological Actions : Cytoprotective
Problem Substances : Acrylamide , Aluminum Chloride
[+]

Extra virgin olive oil polar phenolic compounds decreased malondialdehyde and TNF-α in hearts of cholesterol-fed rats.Jun 09, 2015

Pubmed Data : Eur J Nutr. 2015 Jun 10. Epub 2015 Jun 10. PMID: 26058880
Article Published Date : Jun 09, 2015
Study Type : Animal Study
Additional Links
Substances : Olive Oil
Diseases : High Fat Diet
Pharmacological Actions : Cardioprotective, Malondialdehyde Down-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Extra-virgin olive oil exerts a neuroprotective activity against oxidative damage in brain induced by 2,4-D.Feb 29, 2016

Pubmed Data : J Food Sci Technol. 2016 Mar ;53(3):1454-64. Epub 2016 Jan 5. PMID: 27570270
Article Published Date : Feb 29, 2016
Study Type : Animal Study
Additional Links
Substances : Olive Oil
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Extravirgin olive oil up-regulates CB₁ tumor suppressor gene in human colon cancer cells.Feb 28, 2015

Pubmed Data : J Nutr Biochem. 2015 Mar ;26(3):250-8. Epub 2014 Dec 3. PMID: 25533906
Article Published Date : Feb 28, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Olive Oil
Diseases : Colon Cancer
Pharmacological Actions : Antiproliferative , Chemopreventive
Additional Keywords : Cannabinoid Receptors, Endocannabinoid System, Epigenetic Modification In Cancer, Plant Extracts
[+]

Hydroxytyrosol acetate supplements might provide a basis for developing a new dietary strategy for the prevention of rheumatoid arthritis.Sep 17, 2015

Pubmed Data : Mol Nutr Food Res. 2015 Sep 18. Epub 2015 Sep 18. PMID: 26382723
Article Published Date : Sep 17, 2015
Study Type : Animal Study
Additional Links
Substances : Olive Oil
Diseases : Oxidative Stress, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation
[+]

Olive oil and N. sativa oil have a protective effect against carbon tetrachloride induced hepatotoxicity.Nov 03, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2016 Nov 4 ;16(1):438. Epub 2016 Nov 4. PMID: 27814700
Article Published Date : Nov 03, 2016
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed), Olive Oil
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Hepatoprotective
Additional Keywords : Plant Extracts
[+]

Olive oil can effectively reduce bone loss in ovariectomized rats.Apr 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2016 May ;11(5):1881-1888. Epub 2016 Mar 10. PMID: 27168821
Article Published Date : Apr 30, 2016
Study Type : Animal Study
Additional Links
Substances : Olive Oil
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Olive oil contains protective agents that block the expansion of brain core at the expense of penumbral neurons.Oct 31, 2015

Pubmed Data : Nutrition. 2015 Nov-Dec;31(11-12):1430-42. Epub 2015 Jul 2. PMID: 26429666
Article Published Date : Oct 31, 2015
Study Type : Animal Study
Additional Links
Substances : Coconut Oil, Grape Seed Extract, Olive Oil
Diseases : Brain Inflammation , Stroke: Attenuation/Recovery , Stroke: Ischemic
Pharmacological Actions : Neuroprotective Agents
[+]

Olive oil prevents bone loss in tumor patients and has excellent prospects for curing osteoporosis after menopause.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Interv Aging. 2014 ;9:2087-95. Epub 2014 Dec 2. PMID: 25506212
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Olive Oil
Diseases : Cervical Cancer, Endometrial Cancer, Osteoporosis, Ovarian Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, Malondialdehyde Down-regulation
[+]

Supplementation with antioxidant-rich extra virgin olive oil prevents hepatic oxidative stress in mice fed a high-fat diet.May 16, 2016

Pubmed Data : Nutrition. 2016 May 17. Epub 2016 May 17. PMID: 27346714
Article Published Date : May 16, 2016
Study Type : Animal Study
Additional Links
Substances : Olive Oil
Diseases : High Fat Diet, Oxidative Stress
Pharmacological Actions : Antioxidants, Hepatoprotective
[+]

The resulting data demonstrate the effectiveness of pre-exposure to olive oil polyphenols extract in stimulating liver regeneration.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2016 ;2016:9191407. Epub 2016 Jan 26. PMID: 26925195
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Olive Oil, Polyphenols
Diseases : Liver Damage
Pharmacological Actions : Hepatoprotective, Nrf2 activation, Regenerative
Additional Keywords : Plant Extracts
[+]

The results of this study suggest that the long-term consumption of EVOO-containing diet starting at early age provides a protective effect against AD and its related disorder CAA.Aug 12, 2015

Pubmed Data : J Nutr Biochem. 2015 Aug 13. Epub 2015 Aug 13. PMID: 26344778
Article Published Date : Aug 12, 2015
Study Type : Transgenic Animal Study
Additional Links
Substances : Olive Oil
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Dietary Modification
[+]

Virgin olive oil fortified with vitamin D3 is able to counteract the bone loss induced by estrogen deprivation.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2014 ;9(12):e115817. Epub 2014 Dec 31. PMID: 25551374
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Olive Oil, Polyphenols, Vitamin D
Diseases : Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Bone Density Conservation Agents
Additional Keywords : Natural Substance Synergy
[+]

A review of the dietary treatments for nonalcoholic fatty liver disease.Oct 06, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : World J Gastroenterol. 2015 Oct 7 ;21(37):10621-35. PMID: 26457022
Article Published Date : Oct 06, 2015
Study Type : Review
Additional Links
Substances : Avocado, Black Tea, Coffee, Fish, Fish Oil, Green Tea, Nuts, Olive Oil, Red Wine Extract, Walnut
Diseases : Nonalcoholic fatty liver disease (NAFLD)
[+]

Extra-virgin olive oil polyphenols induced strong tumoricidal effects by selectively triggering apoptotic cell death in HER2-positive cells.Dec 31, 2008

Pubmed Data : Int J Oncol. 2009 Jan ;34(1):43-51. PMID: 19082476
Article Published Date : Dec 31, 2008
Study Type : In Vitro Study
Additional Links
Substances : Olive Oil, Polyphenols
Diseases : Breast Cancer, Breast Cancer: HER-2 Overexpressed
Pharmacological Actions : Anti-metastatic, Anti-Tumor, Apoptotic
Additional Keywords : Plant Oils, Selective Cytotoxicity
[+]

Extra-virgin olive oil polyphenols may inhibit breast cancer through interfering with fatty acid synthesis. Feb 01, 2009

Pubmed Data : Clin Nutr. 2009 Feb;28(1):34-8. Epub 2008 Nov 29. PMID: 18813848
Article Published Date : Feb 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Olive, Olive Oil, Polyphenols
Diseases : Breast Cancer
[+]

Minor components of olive oil inhibit proatherogenic adhesion molecules involved in early atherogenesis. May 03, 2006

Pubmed Data : J Agric Food Chem. 2006 May 3;54(9):3259-64. PMID: 16637682
Article Published Date : May 03, 2006
Study Type : In Vitro Study
Additional Links
Substances : Olive, Olive Oil
Diseases : Arteriosclerosis, Endothelial Dysfunction
Pharmacological Actions : Intercellular adhesion molecule 3 down-regulation
[+]

Nutrigenomics of extra-virgin olive oil: A review.Aug 31, 2016

Pubmed Data : Biofactors. 2016 Sep 1. Epub 2016 Sep 1. PMID: 27580701
Article Published Date : Aug 31, 2016
Study Type : Review
Additional Links
Substances : Olive Oil
Diseases : Cancers: All, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Oleocanthal had a remarkable and selective activity on human melanoma cells.Jun 06, 2016

Pubmed Data : Nutr Cancer. 2016 Jun 7:1-5. Epub 2016 Jun 7. PMID: 27266366
Article Published Date : Jun 06, 2016
Study Type : In Vitro Study
Additional Links
Substances : Oleocanthal, Olive Oil
Diseases : Melanoma
Pharmacological Actions : Bcl-2 protein down-regulation, Cytotoxic
Additional Keywords : Selective Cytotoxicity
[+]

Oleocanthal treatment caused a marked downregulation of phosphorylated mTOR in metastatic breast cancer cell line (MDA-MB-231).Aug 06, 2015

Pubmed Data : Phytother Res. 2015 Aug 7. Epub 2015 Aug 7. PMID: 26248874
Article Published Date : Aug 06, 2015
Study Type : In Vitro Study
Additional Links
Substances : Oleocanthal, Olive Oil
Diseases : Breast Cancer: Triple Negative
Pharmacological Actions : AKT-mammalian target of rapamycin (mTOR) pathway inhibitor
[+]

Oleuropein and hydroxytyrosol, two polyphenols contianed within extra-virgin olive oil, inhibit MCF-7 breast cancer cell proliferation. Dec 10, 2009

Pubmed Data : Mol Nutr Food Res. 2009 Dec 10. PMID: 20013881
Article Published Date : Dec 10, 2009
Study Type : In Vitro Study
Additional Links
Substances : Hydroxytyrosol, Oleuropein, Olive, Olive Oil, Polyphenols
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative , Chemopreventive
[+]

Olive oil phenolics have significant cardioprotective effects. Jan 01, 2005

Pubmed Data : Int J Vitam Nutr Res. 2005 Jan;75(1):61-70. PMID: 15830923
Article Published Date : Jan 01, 2005
Study Type : In Vitro Study
Additional Links
Substances : Hydroxytyrosol, Oleuropein, Olive Oil
Diseases : Arteriosclerosis, Cholesterol: Oxidation
Pharmacological Actions : Antioxidants, Vascular Cell Adhesion Molecule-1 Inhibitor
[+]

Olive oil phenols could be promising multi-targeting agents against Alzheimer's disease.Dec 31, 2014

Pubmed Data : Adv Exp Med Biol. 2015 ;863:1-20. PMID: 26092624
Article Published Date : Dec 31, 2014
Study Type : Review
Additional Links
Substances : Olive Oil
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Phenolic compounds within virgin olive oil inhibit LDL cholesterol oxidation. Feb 08, 2003

Pubmed Data : Med Clin (Barc). 2003 Feb 8;120(4):128-31. PMID: 12605836
Article Published Date : Feb 08, 2003
Study Type : In Vitro Study
Additional Links
Substances : Caffeic Acid, Flavonoids, Oleuropein, Olive, Olive Oil
Diseases : Cholesterol: Oxidation
Therapeutic Actions : Dietary Modification: Mediterranean Diet
Pharmacological Actions : Antioxidants, Vasodilator Agents
[+]

Synergy was observed between olive oil and tomato carotenoids in inhibiting HT-29 cancer cell proliferation.Apr 06, 2016

Pubmed Data : J Sci Food Agric. 2016 Apr 7. Epub 2016 Apr 7. PMID: 27060896
Article Published Date : Apr 06, 2016
Study Type : In Vitro Study
Additional Links
Substances : Olive Oil, Tomato
Diseases : Colon Cancer
Pharmacological Actions : Antiproliferative
Additional Keywords : Cultivars, Natural Substance Synergy, Selective Cytotoxicity
[+]

The in vitro and in vivo neuroprotective effects together with its multiple mechanisms of action are reviewed here.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2015 ;20(3):4655-80. Epub 2015 Mar 13. PMID: 25781069
Article Published Date : Dec 31, 2014
Study Type : Review
Additional Links
Substances : Olive Oil
Diseases : Neurodegenerative Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

The present review critically appraises the available evidence to date, with particular focus on emerging novel biomarkers for disease risk assessment.Jul 31, 2015

Pubmed Data : Proc Nutr Soc. 2015 Aug ;74(3):268-81. PMID: 26186673
Article Published Date : Jul 31, 2015
Study Type : Review
Additional Links
Substances : Olive Oil
Diseases : Chronic Disease, Inflammation
Therapeutic Actions : Dietary Modification: Mediterranean Diet
Additional Keywords : Risk Reduction

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