Organosulfur Compounds

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Name	Cumulative Knowledge	Article Count	Focus Articles
Oxidative Stress	32	16	Log in \| Sign up
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View the Evidence: Substances

Acetylcysteine is beneficial in treating idiopathic pulmonary fibrosis. - Article 2

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Pubmed Data : Thorax. 1995 Sep;50 Suppl 1:S53-8. PMID: 7570466

Article Published Date : Sep 01, 1995

Study Type : Human Study

Additional Links

Substances : Cysteine (see N-Acetylcysteine) : CK(339) : AC(15)

Diseases : Interstitial Lung Diseases : CK(70) : AC(12)

Allicin extract and sodium bicarbonate may be suitable as drug alternatives in prevention of thrush in newborn infants.

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Pubmed Data : Zhongguo Zhong Xi Yi Jie He Za Zhi. 1992 Jan;12(1):28-9, 6. PMID: 1320966

Article Published Date : Jan 01, 1992

Study Type : Human Study

Additional Links

Substances : Allicin : CK(492) : AC(20), Sodium Bicarbonate : CK(68) : AC(11)

Diseases : Thrush : CK(20) : AC(2)

Broccoli sprouts reduce colonization and attenuate gastritis in Helicobacter pylori-infected mice and humans.

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Pubmed Data : Cancer Prev Res (Phila Pa). 2009 Apr;2(4):353-60. PMID: 19349290

Article Published Date : Apr 01, 2009

Study Type : Human Study

Additional Links

Substances : Broccoli : CK(426) : AC(185), Sprouts : CK(76) : AC(36), Sulforaphane : CK(484) : AC(167)

Diseases : Gastritis : CK(48) : AC(8), Helicobacter Pylori Infection : CK(305) : AC(61)

Cystine (a dipeptide of cysteine) and theanine supplementation restores high-Intensity resistance exercise-induced atenuation of natural killer cell activity in well-trained men.

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Pubmed Data : J Strength Cond Res. 2010 Feb 9. Epub 2010 Feb 9. PMID: 20145562

Article Published Date : Feb 09, 2010

Study Type : Human Study

Additional Links

Substances : Cysteine (see N-Acetylcysteine) : CK(339) : AC(15), Theanine : CK(951) : AC(283)

Diseases : Athletic Performance: Recovery : CK(160) : AC(16), Immune Disorders: Low Immune Function : CK(488) : AC(115)

L-cystine and l-theanine may contribute to enhancing the immune response against the H1N1 virus.

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Pubmed Data : Geriatr Gerontol Int. 2008 Dec;8(4):243-50. PMID: 19149835

Article Published Date : Dec 01, 2008

Study Type : Human Study

Additional Links

Substances : Cysteine (see N-Acetylcysteine) : CK(339) : AC(15), Theanine : CK(951) : AC(283)

Diseases : Influenza in Swine : CK(17) : AC(6), Swine Flu Associated Virus : CK(156) : AC(33)

Additional Keywords : Drug-Plant-Vitamin Synergies : CK(1011) : AC(268)

MSM contributes to the improvement of the symptoms of rosacea.

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Pubmed Data : J Cosmet Dermatol. 2008 Mar;7(1):8-14. PMID: 18254805

Article Published Date : Mar 01, 2008

Study Type : Human Study

Additional Links

Substances : Milk Thistle : CK(226) : AC(55), MSM (Methylsulfonylmethane) : CK(63) : AC(8)

Diseases : Rosacea : CK(175) : AC(21)

MSM improves symptoms of pain and physical function in those with osteoarthritis.

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Pubmed Data : Osteoarthritis Cartilage. 2006 Mar;14(3):286-94. Epub 2005 Nov 23. PMID: 16309928

Article Published Date : Mar 01, 2006

Study Type : Human Study

Additional Links

Substances : MSM (Methylsulfonylmethane) : CK(63) : AC(8)

Diseases : Osteoarthritis : CK(615) : AC(89)

MSM relieves symptoms in the treatment of seasonal allergic rhinitis.

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Pubmed Data : J Altern Complement Med. 2002 Apr;8(2):167-73. PMID: 12006124

Article Published Date : Apr 01, 2002

Study Type : Human Study

Additional Links

Substances : MSM (Methylsulfonylmethane) : CK(63) : AC(8)

Diseases : Allergic Rhinitis : CK(327) : AC(40)

MSM supplementation has therapeutic value in osteoarthritis.

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Pubmed Data : BMC Complement Altern Med. 2011 ;11:50. Epub 2011 Jun 27. PMID: 21708034

Article Published Date : Jan 01, 2011

Study Type : Human Study

Additional Links

Substances : MSM (Methylsulfonylmethane) : CK(63) : AC(8)

Diseases : Osteoarthritis : CK(615) : AC(89)

N-acetyl cysteine appears to be a safe and moderately effective augmentation strategy in chronic schizophrenia.

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Pubmed Data : Biol Psychiatry. 2008 Sep 1;64(5):361-8. Epub 2008 Apr 23. PMID: 18436195

Article Published Date : Sep 01, 2008

Study Type : Human Study

Additional Links

Substances : Cysteine (see N-Acetylcysteine) : CK(339) : AC(15)

Diseases : Schizophrenia : CK(247) : AC(29)

Oral sulforaphane safely and effectively induces mucosal Phase II enzyme expression in the upper airway of human subjects.

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Pubmed Data : Clin Immunol. 2009 Mar;130(3):244-51. Epub 2008 Nov 22. PMID: 19028145

Article Published Date : Mar 01, 2009

Study Type : Human Study

Additional Links

Substances : Sulforaphane : CK(484) : AC(167)

Diseases : COPD : CK(138) : AC(17), Cystic Fibrosis : CK(703) : AC(77), Glutathione Deficiency : CK(63) : AC(14), Lung Diseases : CK(32) : AC(5), Pulmonary Fibrosis : CK(149) : AC(48), Respiratory Diseases : CK(174) : AC(29)

Pharmacological Actions : Antioxidants : CK(3503) : AC(1292), Glutathione Upregulation : CK(154) : AC(48), Phase II Detoxification Enzyme Inducer : CK(64) : AC(31)

Additional Keywords : Isothiocyanates : CK(70) : AC(23)

Oral supplementation of MSM has alleviating effects on known markers of oxidative stress following acute bouts of exercise in healthy young men.

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Pubmed Data : J Pharm Pharmacol. 2011 Oct ;63(10):1290-4. Epub 2011 Aug 1. PMID: 21899544

Article Published Date : Oct 01, 2011

Study Type : Human Study

Additional Links

Substances : MSM (Methylsulfonylmethane) : CK(63) : AC(8)

Diseases : Athletic Performance: Recovery : CK(160) : AC(16), Oxidative Stress : CK(1867) : AC(710)

Pharmacological Actions : Antioxidants : CK(3503) : AC(1292), Glutathione Upregulation : CK(154) : AC(48)

Raw broccoli results in faster absorption, higher bioavailability, and higher peak plasma amounts of sulforaphane, compared to cooked broccoli.

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Pubmed Data : J Agric Food Chem. 2008 Nov 26;56(22):10505-9. PMID: 18950181

Article Published Date : Nov 26, 2008

Study Type : Human Study

Additional Links

Substances : Broccoli : CK(426) : AC(185), Sulforaphane : CK(484) : AC(167)

Pharmacological Actions : Anticarcinogenic Agents : CK(513) : AC(265)

Additional Keywords : Raw versus Cooked : CK(68) : AC(12)

Safety Study: Brocolli sprouts (sulforaphane) are safe, tolerable and do not adversely effect thyroid hormone levels.

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Pubmed Data : Nutr Cancer. 2006;55(1):53-62. PMID: 16965241

Article Published Date : Jan 01, 2006

Study Type : Human Study

Additional Links

Substances : Broccoli : CK(426) : AC(185), Sprouts : CK(76) : AC(36), Sulforaphane : CK(484) : AC(167)

Pharmacological Actions : Anticarcinogenic Agents : CK(513) : AC(265)

Additional Keywords : Isothiocyanates : CK(70) : AC(23), Plant Extracts : CK(3401) : AC(1158)

Sulforaphane has a novel chemopreventive mechanism in human colon cancer cells and prostate epithelial cells, namely the inhibition of histone deacetylase (HDAC). I

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Pubmed Data : Exp Biol Med (Maywood). 2007 Feb;232(2):227-34. PMID: 17259330

Article Published Date : Feb 01, 2007

Study Type : Human Study

Additional Links

Substances : Sulforaphane : CK(484) : AC(167)

Diseases : Colon Cancer : CK(819) : AC(233), Prostate Cancer : CK(956) : AC(288), Prostate Cancer: Prevention : CK(145) : AC(16)

Pharmacological Actions : Chemopreventive : CK(1314) : AC(355), Enzyme Inhibitors : CK(386) : AC(208), Histone deacetylase inhibitor : CK(26) : AC(16)

Sulforaphane protects against chemically-induced damage in bladder cells and tissues.

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Pubmed Data : Phytother Res. 2003 Jan;17(1):66-9. PMID: 20810543

Article Published Date : Jan 01, 2003

Study Type : Human Study

Additional Links

Substances : Sulforaphane : CK(484) : AC(167)

Diseases : Bladder Cancer : CK(179) : AC(60), Bladder Degeneration : CK(22) : AC(3), DNA damage : CK(680) : AC(293)

Pharmacological Actions : Chemopreventive : CK(1314) : AC(355), Genoprotective : CK(116) : AC(48)

Sulforaphane-containing broccoli sprout extracts induce a cytoprotective phase 2 response in mouse and human skin.

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Pubmed Data : Cancer Epidemiol Biomarkers Prev. 2007 Apr;16(4):847-51. PMID: 17416783

Article Published Date : Apr 01, 2007

Study Type : Human Study

Additional Links

Substances : Broccoli : CK(426) : AC(185), Sulforaphane : CK(484) : AC(167)

Diseases : Skin Diseases : CK(46) : AC(9)

Pharmacological Actions : Phase II Detoxification Enzyme Inducer : CK(64) : AC(31)

Additional Keywords : Plant Extracts : CK(3401) : AC(1158)

The bioavailability of isothiocyanates from fresh broccoli is approximately three times greater than that from cooked broccoli,

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Pubmed Data : Nutr Cancer. 2000;38(2):168-78. PMID: 11525594

Article Published Date : Jan 01, 2000

Study Type : Human Study

Additional Links

Substances : Broccoli : CK(426) : AC(185), Sulforaphane : CK(484) : AC(167)

Pharmacological Actions : Anticarcinogenic Agents : CK(513) : AC(265)

Additional Keywords : Raw versus Cooked : CK(68) : AC(12)

The garlic compound allicin improves Helicobacter pylori eradication outcomes in patients who are HP positive in biopsy.

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Pubmed Data : Acta Medica (Hradec Kralove). 2001;44(3):97-100. PMID: 11811084

Article Published Date : Jan 01, 2001

Study Type : Human Study

Additional Links

Substances : Allicin : CK(492) : AC(20)

Diseases : Helicobacter Pylori Infection : CK(305) : AC(61)

Additional Keywords : Drug-Plant-Vitamin Synergies : CK(1011) : AC(268)

Theanine/cysteine intake suppresses exercise-induced neutrophilia and lymphopenia in athletes.

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Pubmed Data : J Int Soc Sports Nutr. 2010;7(1):23. Epub 2010 Jun 4. PMID: 20525371

Article Published Date : Jan 01, 2010

Study Type : Human Study

Additional Links

Substances : Cysteine (see N-Acetylcysteine) : CK(339) : AC(15), Theanine : CK(951) : AC(283)

Diseases : Athletic Performance : CK(489) : AC(63), Athletic Performance: Recovery : CK(160) : AC(16), Lymphopenia : CK(11) : AC(2), Neutrophils: Elevated : CK(11) : AC(2)

The addition of broccoli and watercress in the diet may reduce risk of breast cancer

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Pubmed Data : Toxicol Appl Pharmacol. 2005 Dec 1 ;209(2):105-13. Epub 2005 Jun 13. PMID: 15953625

Article Published Date : Dec 01, 2005

Study Type : Human In Vitro

Additional Links

Substances : Broccoli : CK(426) : AC(185), Sulforaphane : CK(484) : AC(167), Watercress : CK(14) : AC(4)

Diseases : Breast Cancer : CK(2051) : AC(566)

Pharmacological Actions : Anticarcinogenic Agents : CK(513) : AC(265), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(149) : AC(71)

Additional Keywords : Isothiocyanates : CK(70) : AC(23), Plant Extracts : CK(3401) : AC(1158)

Allicin exhibits antitumor activity in mouse lymphoma.

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Pubmed Data : Asian Pac J Cancer Prev. 2010 ;11(5):1241-4. PMID: 21198270

Article Published Date : Jan 01, 2010

Study Type : Animal Study

Additional Links

Substances : Allicin : CK(492) : AC(20)

Diseases : Lymphoma : CK(225) : AC(68)

Pharmacological Actions : Anti-Proliferative : CK(55) : AC(49), Apoptotic : CK(1416) : AC(1089)

Allicin in garlic protects against coronary endothelial dysfunction and right heart hypertrophy in pulmonary hypertensive rats.

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Pubmed Data : Am J Physiol Heart Circ Physiol. 2006 Nov;291(5):H2431-8. Epub 2006 May 26. PMID: 16731642

Article Published Date : Nov 01, 2006

Study Type : Animal Study

Additional Links

Substances : Allicin : CK(492) : AC(20), Garlic : CK(466) : AC(155)

Diseases : Endothelial Dysfunction : CK(875) : AC(173), Hypertension: Pulmonary : CK(1830) : AC(34), Right Ventricular Hypertrophy : CK(22) : AC(11)

Additional Keywords : Plant Extracts : CK(3401) : AC(1158)

Allicin may have therapeutic effects on lead poisoning.

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Pubmed Data : Biol Trace Elem Res. 2008 Winter;126(1-3):141-7. Epub 2008 Aug 22. PMID: 18719860

Article Published Date : Dec 01, 2008

Study Type : Animal Study

Additional Links

Substances : Allicin : CK(492) : AC(20)

Diseases : Lead Poisoning : CK(173) : AC(34)

Benzyl isothiocyanate and sulforaphane protect against initiation of pancreatic carcinogenesis in hamsters.

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Pubmed Data : Cancer Lett. 2006 Sep 28;241(2):275-80. Epub 2006 Jan 4. PMID: 16386831

Article Published Date : Sep 28, 2006

Study Type : Animal Study

Additional Links

Substances : Benzyl isothiocyanate : CK(4) : AC(3), Sulforaphane : CK(484) : AC(167)

Diseases : Pancreatic Cancer : CK(513) : AC(162)

Pharmacological Actions : Chemopreventive : CK(1314) : AC(355), Cyclooxygenase 2 Inhibitors : CK(274) : AC(169)

Additional Keywords : Isothiocyanates : CK(70) : AC(23), Stilbenes : CK(414) : AC(242)

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