Download Now

Your Token Count	0
Product Token Price	40

Sign in to Purchase/Download Documents

Sign in / Register

User login

Social Networking

Support Free Media

Pine Bark Extract

User Options

A Membership is required. Please Login or Create an account to get started

Purchase the Exhaustive Downloadable Document on this Topic

Make a Request for GMI to add more Articles on this Topic Immediately (Purchase Required)

View a Printer Friendly version of this page

E-mail this page to a friend

Perform a Search with this Topic

Hover over an icon for more information

Additional Topics Details for this Page

Article Count - 62
Cumulative Knowledge - 395

Advanced Database Options

Limit Articles Displayed by the Following Study Types

Available Sorting Options

Limited to Members Only

By default, all articles on GreenMedInfo.com are sorted based on the content type which best reflects the data which most users are searching for. For instance, people viewing substances are generally most interested in viewing diseases that these substances have shown to have positive influences. This section is for allowing more advanced sorting methods. Currently, these advanced sorting methods are available for members only. If you are already a member, you can sign in by clicking here. If you do not currently have a user account, and would like to create one/become a member, click here to begin the singup process.

Currently Available Sorting Options

Article Published Date - Sort all displayed articles by their published date
Quick Summary Fieldsets - Sort alphabetically, rather than by Cumulative Knowledge
Cumulative Knowledge - Default sorting method. Allows you to sort descendingly

What is Cumulative Knowledge?

Cumulative Knowledge is determined by ascribing a numerical value to the various study types weighted in descending order as follows: (1) Meta-Analysis; (2) Human Study; (3) Human: Case Study; (4) Animal: Transgenic; (5) Animal; (6) In Vitro; (7) Review; and (8) Commentary.

Click here for a more thorough explanation.

Quick Summary: Current access displays 2 out of 81 associated Diseases

Name	Cumulative Knowledge	Article Count	Focus Articles
Hypertension	50	5	Log in \| Sign up
Inflammation	31	3	Log in \| Sign up

Quick Summary: Current access displays 2 out of 26 associated Pharmacological Actions

Name	Cumulative Knowledge	Article Count	Focus Articles
Platelet Aggregation Inhibitors	40	4	Log in \| Sign up
Hypoglycemic Agents	20	2	Log in \| Sign up

Currently Viewing Free Sample of Member Only Features

Although all 19,000+ articles on GreenMedInfo.com are made entirely free to view as an educational service to the public, we provide a powerful set of enhanced data comprehension and retrieval tools for subscribing members. Above you are viewing a free preview, limited to 2 rows, of the membership feature called "Cumulative Knowledge" (learn more).

The Focus Article Feature is not enabled.

Upgrading to the Member role gives you access to unlimited rows of Cumulative Knowledge data.

To Participate

Click here to login
Click here to create an account

View the Evidence: Substances

"Supplementation with Pycnogenol® improves signs and symptoms of menopausal transition."

Click here to read the entire abstract

Pubmed Data : Panminerva Med. 2011 Sep ;53(3 Suppl 1):65-70. PMID: 22108479

Article Published Date : Sep 01, 2011

Study Type : Human Study

Additional Links

Substances : Pycnogenol (Pine Bark) : CK(385) : AC(61)

Diseases : Hot Flash : CK(203) : AC(19), Menopausal Syndrome : CK(171) : AC(27), Premenopausal Disorders : CK(30) : AC(3)

A combination of bilberry and pycnogenol reduces intraocular hypertension and may lower the risk of symptomatic glaucoma.

Click here to read the entire abstract

Pubmed Data : Mol Vis. 2008;14:1288-92. Epub 2008 Jul 10. PMID: 18618008

Article Published Date : Jan 01, 2008

Study Type : Human Study

Additional Links

Substances : Bilberry : CK(39) : AC(11), Pycnogenol (Pine Bark) : CK(385) : AC(61)

Diseases : Glaucoma : CK(111) : AC(19), Intraocular hypertension : CK(32) : AC(4)

A combination of pine bark extract and L-arginine is effective for long-term improvement of erectile function.

Click here to read the entire abstract

Pubmed Data : BJU Int. 2010 Feb 22. Epub 2010 Feb 22. PMID: 20184576

Article Published Date : Feb 22, 2010

Study Type : Human Study

Additional Links

Substances : Arginine : CK(970) : AC(169), Pycnogenol (Pine Bark) : CK(385) : AC(61)

Diseases : Erectile Dysfunction : CK(510) : AC(41)

A multi-nutrient mixture of marine proteins, alpha-lipoic acid, pine bark extract, vitamins and minerals is safe and efficacious in the treatment of aging symptoms of the skin in women.

Click here to read the entire abstract

Pubmed Data : J Int Med Res. 2005 May-Jun;33(3):267-72. PMID: 15938587

Article Published Date : May 01, 2005

Study Type : Human Study

Additional Links

Substances : Alpha-Lipoic Acid : CK(384) : AC(82), Fish extract : CK(32) : AC(4), Multivitamin : CK(243) : AC(22), Pine Bark Extract : CK(395) : AC(62)

Diseases : Aging Skin : CK(360) : AC(86)

A multi-nutrient mixture of vitamin C, vitamin E, carotenoids, selenium, zinc, amino acids and glycosaminoglycans, blueberry extract and pycnogenol improves visible signs of ageing in women 45-73 years of age.

Click here to read the entire abstract

Pubmed Data : J Dermatolog Treat. 2004 Jul;15(4):222-6. PMID: 15764035

Article Published Date : Jul 01, 2004

Study Type : Human Study

Additional Links

Substances : Amino Acids : CK(100) : AC(16), Blueberry : CK(140) : AC(39), Glycosaminoglycans : CK(12) : AC(2), Pycnogenol (Pine Bark) : CK(385) : AC(61), Selenium : CK(574) : AC(94), Vitamin C : CK(1274) : AC(238), Vitamin E : CK(1285) : AC(221), Zinc : CK(870) : AC(127)

Diseases : Aging Skin : CK(360) : AC(86), Skin Diseases : CK(46) : AC(9)

Antioxidant therapy with pine bark, vitamin C and vitamin E may be beneficial in the treatment of drug-refractory migraine possibly reducing headache frequency and severity.

Click here to read the entire abstract

Pubmed Data : Headache. 2006 May;46(5):788-93. PMID: 16643582

Article Published Date : May 01, 2006

Study Type : Human Study

Additional Links

Substances : Pine Bark Extract : CK(395) : AC(62), Vitamin C : CK(1274) : AC(238), Vitamin E : CK(1285) : AC(221)

Diseases : Migraine Disorders : CK(486) : AC(58)

French maritime pine bark extract (Pycnogenol) displays anti-inflammatory effects in vivo.

Click here to read the entire abstract

Pubmed Data : J Inflamm (Lond). 2006;3:1. Epub 2006 Jan 27. PMID: 16441890

Article Published Date : Jan 01, 2006

Study Type : Human Study

Additional Links

Substances : Pycnogenol (Pine Bark) : CK(385) : AC(61)

Diseases : Inflammation : CK(1077) : AC(363)

Pharmacological Actions : Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(49) : AC(30), NF-kappaB Inhibitor : CK(595) : AC(401)

Oral administration of French maritime pine bark extract (Flavangenol(®)) improves clinical symptoms in photoaged facial skin.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Clin Interv Aging. 2012 ;7:275-86. Epub 2012 Jul 27. PMID: 22956863

Article Published Date : Dec 31, 2011

Study Type : Human Study

Additional Links

Substances : Pycnogenol (Pine Bark) : CK(385) : AC(61)

Diseases : Aging Skin : CK(360) : AC(86)

Additional Keywords : Phytotherapy : CK(177) : AC(27), Plant Extracts : CK(3572) : AC(1216), Proanthocyanidins : CK(159) : AC(46)

Pcynogenol has protective effects on kidney flow and function in hypertension and reduces C-reactive proein.

Click here to read the entire abstract

Pubmed Data : J Cardiovasc Pharmacol Ther. 2010 Mar;15(1):41-6. Epub 2010 Jan 22. PMID: 20097689

Article Published Date : Mar 01, 2010

Study Type : Human Study

Additional Links

Substances : Pycnogenol (Pine Bark) : CK(385) : AC(61)

Diseases : Elevated CRP : CK(72) : AC(8), Hypertension : CK(2783) : AC(271), Kidney Diseases : CK(424) : AC(71)

Pcynogenol significantly reduces severity of symptoms in patients with systemic lupus erythematosus.

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2001 Dec;15(8):698-704. PMID: 11746863

Article Published Date : Dec 01, 2001

Study Type : Human Study

Additional Links

Substances : Pine Bark Extract : CK(395) : AC(62)

Diseases : Lupus Erythematosus: Systemic : CK(949) : AC(53)

Pine bark extract significantly lowers pain medication requirement in dysmenorrhea.

Click here to read the entire abstract

Pubmed Data : Prev Med. 2009 Aug-Sep;49(2-3):184-9. Epub 2009 Jun 23. PMID: 18567279

Article Published Date : Aug 01, 2009

Study Type : Human Study

Additional Links

Substances : Pine Bark Extract : CK(395) : AC(62)

Diseases : Dysmenorrhea : CK(409) : AC(26)

Pharmacological Actions : Analgesics : CK(372) : AC(78)

Additional Keywords : Drug Sparing : CK(451) : AC(49)

Pine bark extract significantly reduces oxidative stress in children with ADHD.

Click here to read the entire abstract

Pubmed Data : Redox Rep. 2006;11(4):163-72. PMID: 16984739

Article Published Date : Jan 01, 2006

Study Type : Human Study

Additional Links

Substances : Pine Bark Extract : CK(395) : AC(62)

Diseases : Attention Deficit Disorder with Hyperactivity : CK(240) : AC(30)

Pine bark extract significantly reduces pain in osteoarthritis.

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2008 Aug;22(8):1087-92. PMID: 18570266

Article Published Date : Aug 01, 2008

Study Type : Human Study

Additional Links

Substances : Pine Bark Extract : CK(395) : AC(62), Pycnogenol (Pine Bark) : CK(385) : AC(61)

Diseases : Osteoarthritis : CK(615) : AC(91)

Additional Keywords : Drug Sparing : CK(451) : AC(49)

Pine bark inhibits Cox-1 and Cox-2 enzymes, reducing inflammation.

Click here to read the entire abstract

Pubmed Data : Biomed Pharmacother. 2006 Jan;60(1):5-9. Epub 2005 Oct 26. PMID: 16330178

Article Published Date : Jan 01, 2006

Study Type : Human Study

Additional Links

Substances : Pine Bark Extract : CK(395) : AC(62), Pycnogenol (Pine Bark) : CK(385) : AC(61)

Diseases : Inflammation : CK(1077) : AC(363)

Pinebark reduces urinary catecholamines (excitatory neurotransmitters) and reduces hyperactivity in children with ADHD.

Click here to read the entire abstract

Pubmed Data : Nutr Neurosci. 2007 Jun-Aug;10(3-4):151-7. PMID: 18019397

Article Published Date : Jun 01, 2007

Study Type : Human Study

Additional Links

Substances : Pine Bark Extract : CK(395) : AC(62)

Diseases : Attention Deficit Disorder with Hyperactivity : CK(240) : AC(30)

Pycnogenol has antidiabetic action in patients with type 2 diabetes.

Click here to read the entire abstract

Pubmed Data : Life Sci. 2004 Oct 8;75(21):2505-13. PMID: 15363656

Article Published Date : Oct 08, 2004

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(909) : AC(289), Pycnogenol (Pine Bark) : CK(385) : AC(61)

Diseases : Diabetes Mellitus: Type 2 : CK(3429) : AC(341)

Pharmacological Actions : Hypoglycemic Agents : CK(563) : AC(156)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Pycnogenol has therapeutic value in the prevention of jet lag in healthy and hypertensive patients.

Click here to read the entire abstract

Pubmed Data : Minerva Cardioangiol. 2008 Oct;56(5 Suppl):3-9. PMID: 19597404

Article Published Date : Oct 01, 2008

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(909) : AC(289), Pycnogenol (Pine Bark) : CK(385) : AC(61)

Diseases : Brain Edema : CK(14) : AC(3), Hypertension : CK(2783) : AC(271), Jet Lag : CK(33) : AC(5)

Pharmacological Actions : Platelet Aggregation Inhibitors : CK(173) : AC(37)

Pycnogenol improves diabetes control, lowers cardiovascular disease risk factors, and reduces the need for hypertension medication in type diabetic patients.

Click here to read the entire abstract

Pubmed Data : Nutr Res. 2008 May;28(5):315-20. PMID: 19083426

Article Published Date : May 01, 2008

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(909) : AC(289), Pycnogenol (Pine Bark) : CK(385) : AC(61)

Diseases : Cardiovascular Diseases : CK(5138) : AC(641), Diabetes: Cardiovascular Illness : CK(666) : AC(104), Diabetes Mellitus: Type 2 : CK(3429) : AC(341), Hypertension : CK(2783) : AC(271)

Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Hypoglycemic Agents : CK(563) : AC(156)

Additional Keywords : Drug Sparing : CK(451) : AC(49), Plant Extracts : CK(3572) : AC(1216)

Pycnogenol improves endothelial function of hypertensive patients.

Click here to read the entire abstract

Pubmed Data : Life Sci. 2004 Jan 2;74(7):855-62. PMID: 14659974

Article Published Date : Jan 02, 2004

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(909) : AC(289), Pycnogenol (Pine Bark) : CK(385) : AC(61)

Diseases : Endothelial Dysfunction : CK(897) : AC(173), Hypertension : CK(2783) : AC(271)

Pharmacological Actions : Platelet Aggregation Inhibitors : CK(173) : AC(37)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Pycnogenol is efficacious as an adjunct in the management of mild-to-moderate childhood asthma.

Click here to read the entire abstract

Pubmed Data : West J Med. 1998 Dec;169(6):356-63. PMID: 15641632

Article Published Date : Dec 01, 1998

Study Type : Human Study

Additional Links

Substances : Pine Bark Extract : CK(395) : AC(62), Pycnogenol (Pine Bark) : CK(385) : AC(61)

Diseases : Asthma : CK(918) : AC(134), Asthma: Bronchial : CK(267) : AC(33)

Pycnogenol may alleviate adverse effects in oncologic treatment, e.g. deep vein thrombosis.

Click here to read the entire abstract

Pubmed Data : Mol Vis. 2008;14:1288-92. Epub 2008 Jul 10. PMID: 18927527

Article Published Date : Jan 01, 2008

Study Type : Human Study

Additional Links

Substances : Flavonoids : CK(909) : AC(289), Pycnogenol (Pine Bark) : CK(385) : AC(61)

Diseases : Chemotherapy : CK(65) : AC(16), Deep Vein Thrombosis : CK(511) : AC(10), Radiation Induced Illness : CK(1018) : AC(249)

Pharmacological Actions : Antineoplastic Agents : CK(877) : AC(496)

Additional Keywords : Drug Side Effect Attenuation : CK(252) : AC(49)

Pycnogenol may exert anti-inflammatory activity in osteoarthritic joints.

Click here to read the entire abstract

Pubmed Data : Redox Rep. 2008;13(6):271-6. PMID: 19017467

Article Published Date : Jan 01, 2008

Study Type : Human Study

Additional Links

Substances : Pycnogenol (Pine Bark) : CK(385) : AC(61)

Diseases : CRP : CK(30) : AC(3), Fibrinogen: Elevated : CK(114) : AC(13), Osteoarthritis : CK(615) : AC(91)

Related Blogs

The Evidence Against Aspirin And For Natural Alternatives

Written by Sayer Ji, Founder

As far back as the 5th century BC the Greek physician Hippocrates wrote about the use of a bitter powder extracted from willow bark that reduced fevers and eased aches and pains. Native Americans also used an infusion of willow bark for similar purposes. What was this remarkable "healing" principle within the bark that relieved dis-ease?

Print Options

Some features are currently member only features. If you are already a member, please login. Otherwise, click here to become a member.

Printer-friendly version
Send to friend
PDF version