Pycnogenol (Pine Bark) research focused on Cardiovascular Diseases

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130 Diseases Researched for Pycnogenol (Pine Bark)

Name	AC	CK
Hypertension	7	70
Oxidative Stress	10	44
Osteoarthritis	5	43
Erectile Dysfunction	4	40
Inflammation	5	33
Aging Skin	3	30
Asthma	3	23
Atherosclerosis	3	22
Diabetes Mellitus: Type 2	4	22
Asthma: Bronchial	1	20
Attention Deficit Disorder with Hyperactivity	3	20
Cognitive Decline/Dysfunction	2	20
Deep Vein Thrombosis	2	20
Diabetic Microangiopathy	2	20
Glaucoma	2	20
Hemorrhoids	2	20
Lower Urinary Tract Symptoms	2	20
Melasma	1	20
Sperm Count: Low	2	20
Diabetes: Cardiovascular Illness	2	14
Sperm Quality: Low	3	14
Lipid Peroxidation	2	12
Psoriasis	2	12
Radiation Induced Illness	2	12
Endothelial Dysfunction	2	11
Fibrosarcoma	2	11
Athletic Performance	1	10
Athletic Performance: Recovery	1	10
Bladder Dysfunction	1	10
Brain Edema	1	10
C-Reactive Protein	1	10
CRP	1	10
Cardiovascular Disease	1	10
Cardiovascular Disease: Prevention	1	10
Cardiovascular Diseases	1	10
Chemotherapy	1	10
Chronic Venous Insufficency	1	10
Common Cold	1	10
Dysmenorrhea	1	10
Edema	1	10
Elevated CRP	1	10
Fibrinogen: Elevated	1	10
Headache: Migraine	1	10
Homocysteine: Elevated	1	10
Hot Flash	1	10
Intermittent Claudication	1	10
Intraocular hypertension	1	10
Jet Lag	1	10
Kidney Diseases	1	10
Learning disorders	1	10
Lupus Erythematosus: Systemic	1	10
Menopausal Syndrome	1	10
Microangiopathy	1	10
Migraine Disorders	1	10
Perimenopausal Syndrome	1	10
Peripheral Arterial Disease	1	10
Premenopausal Disorders	1	10
Skin Diseases	1	10
Smoking: Cardiovascular Disease	1	10
Thromboembolism	1	10
Thrombophlebitis	1	10
Varicose Veins: Postpartum	1	10
Cervical Cancer	5	8
Chemotherapy-Induced Toxicity: Cisplatin	3	6
Diabetes Mellitus: Type 1	3	5
Aging	1	4
Chronic Obstructive Pulmonary Disease	2	4
Diabetic Amyotrophy	1	4
Diabetic Ulcer	1	4
Hepatitis C	3	4
Thrombosis	1	4
Brain Injury: Traumatic	2	3
Obesity	2	3
Allergic Rhinitis	1	2
Androgen Deficiency	1	2
Breast Cancer	2	2
Candida Infection	1	2
Cataract	1	2
Chemically-Induced Liver Damage	1	2
DNA damage	1	2
Depression	1	2
Dermatitis	1	2
Fluoride Toxicity	1	2
Hepatic Steatosis	1	2
Hydrogen Peroxide Induced Toxicity	1	2
Hyperglycemia	1	2
Infertility: Male	1	2
Inflammatory Bowel Diseases	1	2
Kidney Damage: Drug-Induced	1	2
Lipopolysaccharide-Induced Toxicity	2	2
Lupus Erythematosus: Cutaneous	1	2
Myocardial Ischemia	1	2
Nonalcoholic fatty liver disease (NAFLD)	1	2
Periodontitis	1	2
Radiation Induced Illness: Enteritis	1	2
Scars	1	2
Sepsis	1	2
Skin Cancer: Prevention	1	2
Stress	1	2
Sunburn	1	2
Venous Ulcer	1	2
Wound Healing	1	2
Wound Healing: Delayed	1	2
Allergies	1	1
Anemia: Hemolytic	1	1
Brain Inflammation	1	1
Brain: Microglial Activation	1	1
Cancer Metastasis	1	1
Cancers: All	1	1
Enterococcus Infections	1	1
Epstein-Barr Virus Infections	1	1
Escherichia coli Infections	1	1
Gingivitis	1	1
Glucosephosphate Dehydrogenase Deficiency	1	1
Gout	1	1
HIV Infections	1	1
Hyperpigmentation	1	1
Liver Cancer	1	1
Low Human Growth Hormone	1	1
Lung Cancer	1	1
Oral Cancer	1	1
Ovarian Cancer	1	1
Pancreatic Cancer	1	1
Peroxynitrite Toxicity	1	1
Prostate Cancer	1	1
Pseudomonas aeruginosa	1	1
Sickle Cell Anemia	1	1
Squamous cell carcinoma	1	1
Staphylococcus aureus infection	1	1
Ultraviolet Radiation Induced Damage	1	1

63 Pharmacological Actions Researched for Pycnogenol (Pine Bark)

Name	AC	CK
Antioxidants	24	108
Platelet Aggregation Inhibitors	4	40
Antihypertensive Agents	3	30
Hypoglycemic Agents	3	22
Antineoplastic Agents	3	21
Fertility Agents: Male	2	20
Prophylactic Agents	2	20
Apoptotic	9	18
Anti-Inflammatory Agents	9	14
Antiproliferative	4	13
Matrix metalloproteinase-9 (MMP-9) inhibitor	4	13
NF-kappaB Inhibitor	4	13
Neuroprotective Agents	3	13
Cardioprotective	2	12
Heme oxygenase-1 up-regulation	2	11
Analgesics	1	10
Calcium Channel Blockers	1	10
Catalase Up-Regulation	1	10
Hypolipidemic	1	10
Malondialdehyde Down-regulation	4	8
Chemoprotective Agents	3	6
Antiviral Agents	4	5
Cytoprotective	1	5
Hepatoprotective	3	5
Anti-thrombotic	1	4
Glutathione Upregulation	2	4
Interleukin-4 downregulation	2	4
Renoprotective	2	4
Alpha-glucosidase inhibitor	2	3
Anti-Bacterial Agents	2	3
Anti-metastatic	3	3
Chemopreventive	2	3
Tumor Necrosis Factor (TNF) Alpha Inhibitor	2	3
Alpha-amylase inhibitor	1	2
Anti-Apoptotic	1	2
Anti-Ulcer Agents	1	2
Anti-atherogenic	1	2
Anticarcinogenic Agents	1	2
Antidepressive Agents	1	2
Bcl-2 protein down-regulation	2	2
Chemotherapeutic	2	2
Chondroprotective	1	2
DNA Repair Up-regulation	1	2
Immunomodulatory	1	2
Interleukin-1 beta downregulation	1	2
Interleukin-10 downregulation	1	2
Interleukin-5 downregulation	1	2
Radioprotective	1	2
Superoxide Dismutase Up-regulation	1	2
Vascular Endothelial Growth Factor Inhibitors	1	2
interleukin-13 down-regulation	1	2
Anti-HIV Agents	1	1
Antimicrobial	1	1
Cell cycle arrest	1	1
Cytotoxic	1	1
Enzyme Inhibitors	1	1
Gastrointestinal Agents	1	1
Histamine Antagonists	1	1
Matrix metalloproteinase-2 (MMP-2) inhibitor	1	1
Nitric Oxide Inhibitor	1	1
Photoprotective	1	1
Secretagogue	1	1
Xanthine oxidase inhibitor	1	1

Focused Research Articles 2
Cumulative Knowledge Score 3
Overall Research Rating GOOD

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View the Evidence:
2 Abstracts with Pycnogenol (Pine Bark)
& Cardiovascular Diseases Research

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Pycnogenol improves diabetes control, lowers cardiovascular disease risk factors, and reduces the need for hypertension medication in type diabetic patients. May 01, 2008

Click here to read the entire abstract

Pubmed Data : Nutr Res. 2008 May;28(5):315-20. PMID: 19083426

Article Published Date : May 01, 2008

Study Type : Human Study

Additional Links

Substances : Flavonoids, Pycnogenol (Pine Bark)

Diseases : Cardiovascular Diseases, Diabetes: Cardiovascular Illness, Diabetes Mellitus: Type 2, Hypertension

Pharmacological Actions : Antioxidants, Hypoglycemic Agents

Additional Keywords : Drug Sparing, Plant Extracts

[+]

Pycnogenol may have important role in prevention of cardiovascular diseases.Nov 18, 2018

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2018 Nov 19. Epub 2018 Nov 19. PMID: 30456865

Article Published Date : Nov 18, 2018

Study Type : Review

Additional Links

Substances : Pycnogenol (Pine Bark)

Diseases : Cardiovascular Diseases

Pharmacological Actions : Cardioprotective, Hypolipidemic

Pycnogenol (Pine Bark) Related Articles

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Pycnogenol Boosts Athletic Performance – Who Needs Doping?

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Researchers from Japan's Keiju Medical Center have determined that a certain nutraceutical from pine trees can significantly reduce symptoms of menopause and perimenopause.

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Painful hemorrhoids, high blood pressure and skin issues, such as psoriasis, all have something in common: Blood flow. Research finds these three issues can all be successfully treated with the pine bark extract called Pycnogenol.

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There is a little known natural extract of plant waxes known as policosanol, extractable from sugar cane, yams, and beeswax, which has been giving some of the more profitable drugs on the market a biomedical beating since it was first investigated in clinical trials by the Cubans in the 1990's.

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View the Evidence: 2 Abstracts with Pycnogenol (Pine Bark) & Cardiovascular Diseases Research

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Pycnogenol improves diabetes control, lowers cardiovascular disease risk factors, and reduces the need for hypertension medication in type diabetic patients. May 01, 2008

Click here to read the entire abstract

Pycnogenol may have important role in prevention of cardiovascular diseases.Nov 18, 2018

Click here to read the entire abstract

Pycnogenol (Pine Bark) Related Articles

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Pycnogenol (Pine Bark) research focused on Cardiovascular Diseases

View the Evidence:
2 Abstracts with Pycnogenol (Pine Bark)
& Cardiovascular Diseases Research