Pycnogenol (Pine Bark) research focused on Brain: Microglial Activation

Jump to
Abstracts Focused Research Topics

Focus Your Research

Click any topic below to filter + focus research

130 Diseases Researched for Pycnogenol (Pine Bark)

Name	AC	CK
Hypertension	7	70
Oxidative Stress	10	44
Osteoarthritis	5	43
Erectile Dysfunction	4	40
Inflammation	5	33
Aging Skin	3	30
Asthma	3	23
Atherosclerosis	3	22
Diabetes Mellitus: Type 2	4	22
Asthma: Bronchial	1	20
Attention Deficit Disorder with Hyperactivity	3	20
Cognitive Decline/Dysfunction	2	20
Deep Vein Thrombosis	2	20
Diabetic Microangiopathy	2	20
Glaucoma	2	20
Hemorrhoids	2	20
Lower Urinary Tract Symptoms	2	20
Melasma	1	20
Sperm Count: Low	2	20
Diabetes: Cardiovascular Illness	2	14
Sperm Quality: Low	3	14
Lipid Peroxidation	2	12
Psoriasis	2	12
Radiation Induced Illness	2	12
Endothelial Dysfunction	2	11
Fibrosarcoma	2	11
Athletic Performance	1	10
Athletic Performance: Recovery	1	10
Bladder Dysfunction	1	10
Brain Edema	1	10
C-Reactive Protein	1	10
CRP	1	10
Cardiovascular Disease	1	10
Cardiovascular Disease: Prevention	1	10
Cardiovascular Diseases	1	10
Chemotherapy	1	10
Chronic Venous Insufficency	1	10
Common Cold	1	10
Dysmenorrhea	1	10
Edema	1	10
Elevated CRP	1	10
Fibrinogen: Elevated	1	10
Headache: Migraine	1	10
Homocysteine: Elevated	1	10
Hot Flash	1	10
Intermittent Claudication	1	10
Intraocular hypertension	1	10
Jet Lag	1	10
Kidney Diseases	1	10
Learning disorders	1	10
Lupus Erythematosus: Systemic	1	10
Menopausal Syndrome	1	10
Microangiopathy	1	10
Migraine Disorders	1	10
Perimenopausal Syndrome	1	10
Peripheral Arterial Disease	1	10
Premenopausal Disorders	1	10
Skin Diseases	1	10
Smoking: Cardiovascular Disease	1	10
Thromboembolism	1	10
Thrombophlebitis	1	10
Varicose Veins: Postpartum	1	10
Cervical Cancer	5	8
Chemotherapy-Induced Toxicity: Cisplatin	3	6
Diabetes Mellitus: Type 1	3	5
Aging	1	4
Chronic Obstructive Pulmonary Disease	2	4
Diabetic Amyotrophy	1	4
Diabetic Ulcer	1	4
Hepatitis C	3	4
Thrombosis	1	4
Brain Injury: Traumatic	2	3
Obesity	2	3
Allergic Rhinitis	1	2
Androgen Deficiency	1	2
Breast Cancer	2	2
Candida Infection	1	2
Cataract	1	2
Chemically-Induced Liver Damage	1	2
DNA damage	1	2
Depression	1	2
Dermatitis	1	2
Fluoride Toxicity	1	2
Hepatic Steatosis	1	2
Hydrogen Peroxide Induced Toxicity	1	2
Hyperglycemia	1	2
Infertility: Male	1	2
Inflammatory Bowel Diseases	1	2
Kidney Damage: Drug-Induced	1	2
Lipopolysaccharide-Induced Toxicity	2	2
Lupus Erythematosus: Cutaneous	1	2
Myocardial Ischemia	1	2
Nonalcoholic fatty liver disease (NAFLD)	1	2
Periodontitis	1	2
Radiation Induced Illness: Enteritis	1	2
Scars	1	2
Sepsis	1	2
Skin Cancer: Prevention	1	2
Stress	1	2
Sunburn	1	2
Venous Ulcer	1	2
Wound Healing	1	2
Wound Healing: Delayed	1	2
Allergies	1	1
Anemia: Hemolytic	1	1
Brain Inflammation	1	1
Brain: Microglial Activation	1	1
Cancer Metastasis	1	1
Cancers: All	1	1
Enterococcus Infections	1	1
Epstein-Barr Virus Infections	1	1
Escherichia coli Infections	1	1
Gingivitis	1	1
Glucosephosphate Dehydrogenase Deficiency	1	1
Gout	1	1
HIV Infections	1	1
Hyperpigmentation	1	1
Liver Cancer	1	1
Low Human Growth Hormone	1	1
Lung Cancer	1	1
Oral Cancer	1	1
Ovarian Cancer	1	1
Pancreatic Cancer	1	1
Peroxynitrite Toxicity	1	1
Prostate Cancer	1	1
Pseudomonas aeruginosa	1	1
Sickle Cell Anemia	1	1
Squamous cell carcinoma	1	1
Staphylococcus aureus infection	1	1
Ultraviolet Radiation Induced Damage	1	1

63 Pharmacological Actions Researched for Pycnogenol (Pine Bark)

Name	AC	CK
Antioxidants	24	108
Platelet Aggregation Inhibitors	4	40
Antihypertensive Agents	3	30
Hypoglycemic Agents	3	22
Antineoplastic Agents	3	21
Fertility Agents: Male	2	20
Prophylactic Agents	2	20
Apoptotic	9	18
Anti-Inflammatory Agents	9	14
Antiproliferative	4	13
Matrix metalloproteinase-9 (MMP-9) inhibitor	4	13
NF-kappaB Inhibitor	4	13
Neuroprotective Agents	3	13
Cardioprotective	2	12
Heme oxygenase-1 up-regulation	2	11
Analgesics	1	10
Calcium Channel Blockers	1	10
Catalase Up-Regulation	1	10
Hypolipidemic	1	10
Malondialdehyde Down-regulation	4	8
Chemoprotective Agents	3	6
Antiviral Agents	4	5
Cytoprotective	1	5
Hepatoprotective	3	5
Anti-thrombotic	1	4
Glutathione Upregulation	2	4
Interleukin-4 downregulation	2	4
Renoprotective	2	4
Alpha-glucosidase inhibitor	2	3
Anti-Bacterial Agents	2	3
Anti-metastatic	3	3
Chemopreventive	2	3
Tumor Necrosis Factor (TNF) Alpha Inhibitor	2	3
Alpha-amylase inhibitor	1	2
Anti-Apoptotic	1	2
Anti-Ulcer Agents	1	2
Anti-atherogenic	1	2
Anticarcinogenic Agents	1	2
Antidepressive Agents	1	2
Bcl-2 protein down-regulation	2	2
Chemotherapeutic	2	2
Chondroprotective	1	2
DNA Repair Up-regulation	1	2
Immunomodulatory	1	2
Interleukin-1 beta downregulation	1	2
Interleukin-10 downregulation	1	2
Interleukin-5 downregulation	1	2
Radioprotective	1	2
Superoxide Dismutase Up-regulation	1	2
Vascular Endothelial Growth Factor Inhibitors	1	2
interleukin-13 down-regulation	1	2
Anti-HIV Agents	1	1
Antimicrobial	1	1
Cell cycle arrest	1	1
Cytotoxic	1	1
Enzyme Inhibitors	1	1
Gastrointestinal Agents	1	1
Histamine Antagonists	1	1
Matrix metalloproteinase-2 (MMP-2) inhibitor	1	1
Nitric Oxide Inhibitor	1	1
Photoprotective	1	1
Secretagogue	1	1
Xanthine oxidase inhibitor	1	1

Focused Research Articles 1
Cumulative Knowledge Score 1
Overall Research Rating GOOD

FREE Member Preview Enabled

You are viewing this page with some membership features unlocked
To unlock all the great features and content on GMI, please support us by becoming a Power User member

View the Evidence:
1 Abstracts with Pycnogenol (Pine Bark)
& Brain: Microglial Activation Research

[x] Remove Focus on Brain: Microglial Activation

[+]

Pycnogenol may be developed as a therapeutic agent for the treatment of neuroinflammatory diseases.Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2015 ;10(9):e0137837. Epub 2015 Sep 14. PMID: 26367267

Article Published Date : Dec 31, 2014

Study Type : In Vitro Study

Additional Links

Substances : Pycnogenol (Pine Bark)

Diseases : Brain: Microglial Activation, Brain Inflammation , Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor

Additional Keywords : Dose Response

Pycnogenol (Pine Bark) Related Articles

Yet Another Natural Solution to Help Perimenopausal Symptoms Proven

Written by Case Adams, Naturopath

Researchers from Japan's Keiju Medical Center have determined that a certain nutraceutical from pine trees can significantly reduce symptoms of menopause and perimenopause.

Sugarcane Extract Superior to Cholesterol-Lowering Drugs?

Written by Sayer Ji, Founder

There is a little known natural extract of plant waxes known as policosanol, extractable from sugar cane, yams, and beeswax, which has been giving some of the more profitable drugs on the market a biomedical beating since it was first investigated in clinical trials by the Cubans in the 1990's.

Pine Bark Extract Treats Meniere's Disease

Written by Case Adams, Naturopath

New research finds that pine bark extract significantly treats the tinnitus and vertigo related to Meniere's disease.

How Pine Bark Extract Could Save Air Travelers Lives

Written by Sayer Ji, Founder

Modern air travel carries with it a wide range of health risks, some of which are life-threatening. What can we do to reduce these risks? This amazing plant substance may provide the perfect answer...

The Powerful Aspirin Alternative Your Doctor Never Told You About

Written by Sayer Ji, Founder

Aspirin's long held promises are increasingly falling flat. A natural, safer and more effective alternative to this synthetic drug has been known about for at least 15 years!

Pine Bark Extract Treats Psoriasis, Hemorrhoids, Hypertension

Written by Case Adams, Naturopath

Painful hemorrhoids, high blood pressure and skin issues, such as psoriasis, all have something in common: Blood flow. Research finds these three issues can all be successfully treated with the pine bark extract called Pycnogenol.

5 Natural Remedies for Seasonal Allergy Relief

Written by Tara Thorne, R.H.N

When seasonal allergies strike they can bring with them a host of nasty symptoms including itchy and watery eyes, sneezing, a running nose and sore throat due to post-nasal drip. Medicating with anti-histamines isn’t a healthy option and can leave many feeling drowsy and fatigued. Luckily there are natural remedies that are making waves for their powerful anti-histamine-like effects and abilities to suppress seasonal allergy symptoms.

Skin Age Reversed 13 Years In Just 9 Months By Doing This

Written by Sayer Ji, Founder

One simple lifestyle modification -- the cessation of smoking -- has been found to dramatically reverse biological skin age in a study of Italian women.

Aspirin Has No Benefit, May Increase Cancer Mortality -- NEJM Study Reveals

Written by Sayer Ji, Founder

3 Evidence-Based Ways To Reverse Skin Aging Naturally

Written by Sayer Ji, Founder

Our aging skin is the target of billions of dollars worth of marketing, the object of a continual stream of cosmetics, drugs and 'nutraceuticals' promising to deliver age-defying results. But what really works? What does the scientific evidence say?

The Aspirin Alternative Your Doctor Never Told You About

Written by Sayer Ji, Founder

Millions use aspirin daily without realizing its true dangers. The good news is that there is a natural alternative which preliminary research indicates is safer and more effective.

Pycnogenol Boosts Athletic Performance – Who Needs Doping?

Written by Case Adams, Naturopath

Doping has wrecked the reputations of several sports along with many athletes. Once again nature provides a solution - this time to boost athletic performance.

Print Options

Some features are currently member only features. If you are already a member, please login. Otherwise, click here to become a member.

Printer-friendly version
Send to friend
PDF version

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

Pycnogenol (Pine Bark) research focused on Brain: Microglial Activation jQuery(function ($) { $(".node-field-image").click(function () { $(".node-field-image").toggleClass("open"); }); $(".node.topic>.colfull").click(function () { $(".node.topic>.colfull").toggleClass("open"); }); })

Focus Your Research

Click any topic below to filter + focus research

FREE Member Preview Enabled

View the Evidence: 1 Abstracts with Pycnogenol (Pine Bark) & Brain: Microglial Activation Research

Pycnogenol may be developed as a therapeutic agent for the treatment of neuroinflammatory diseases.Dec 31, 2014

Click here to read the entire abstract

Pycnogenol (Pine Bark) Related Articles

Print Options

Pycnogenol (Pine Bark) research focused on Brain: Microglial Activation

View the Evidence:
1 Abstracts with Pycnogenol (Pine Bark)
& Brain: Microglial Activation Research