Pycnogenol (Pine Bark) research focused on Brain: Microglial Activation

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130 Diseases Researched for Pycnogenol (Pine Bark)

Name	AC	CK
Hypertension	7	70
Oxidative Stress	10	44
Osteoarthritis	5	43
Erectile Dysfunction	4	40
Inflammation	5	33
Aging Skin	3	30
Asthma	3	23
Atherosclerosis	3	22
Diabetes Mellitus: Type 2	4	22
Asthma: Bronchial	1	20
Attention Deficit Disorder with Hyperactivity	3	20
Cognitive Decline/Dysfunction	2	20
Deep Vein Thrombosis	2	20
Diabetic Microangiopathy	2	20
Glaucoma	2	20
Hemorrhoids	2	20
Lower Urinary Tract Symptoms	2	20
Melasma	1	20
Sperm Count: Low	2	20
Diabetes: Cardiovascular Illness	2	14
Sperm Quality: Low	3	14
Lipid Peroxidation	2	12
Psoriasis	2	12
Radiation Induced Illness	2	12
Endothelial Dysfunction	2	11
Fibrosarcoma	2	11
Athletic Performance	1	10
Athletic Performance: Recovery	1	10
Bladder Dysfunction	1	10
Brain Edema	1	10
C-Reactive Protein	1	10
CRP	1	10
Cardiovascular Disease	1	10
Cardiovascular Disease: Prevention	1	10
Cardiovascular Diseases	1	10
Chemotherapy	1	10
Chronic Venous Insufficency	1	10
Common Cold	1	10
Dysmenorrhea	1	10
Edema	1	10
Elevated CRP	1	10
Fibrinogen: Elevated	1	10
Headache: Migraine	1	10
Homocysteine: Elevated	1	10
Hot Flash	1	10
Intermittent Claudication	1	10
Intraocular hypertension	1	10
Jet Lag	1	10
Kidney Diseases	1	10
Learning disorders	1	10
Lupus Erythematosus: Systemic	1	10
Menopausal Syndrome	1	10
Microangiopathy	1	10
Migraine Disorders	1	10
Perimenopausal Syndrome	1	10
Peripheral Arterial Disease	1	10
Premenopausal Disorders	1	10
Skin Diseases	1	10
Smoking: Cardiovascular Disease	1	10
Thromboembolism	1	10
Thrombophlebitis	1	10
Varicose Veins: Postpartum	1	10
Cervical Cancer	5	8
Chemotherapy-Induced Toxicity: Cisplatin	3	6
Diabetes Mellitus: Type 1	3	5
Aging	1	4
Chronic Obstructive Pulmonary Disease	2	4
Diabetic Amyotrophy	1	4
Diabetic Ulcer	1	4
Hepatitis C	3	4
Thrombosis	1	4
Brain Injury: Traumatic	2	3
Obesity	2	3
Allergic Rhinitis	1	2
Androgen Deficiency	1	2
Breast Cancer	2	2
Candida Infection	1	2
Cataract	1	2
Chemically-Induced Liver Damage	1	2
DNA damage	1	2
Depression	1	2
Dermatitis	1	2
Fluoride Toxicity	1	2
Hepatic Steatosis	1	2
Hydrogen Peroxide Induced Toxicity	1	2
Hyperglycemia	1	2
Infertility: Male	1	2
Inflammatory Bowel Diseases	1	2
Kidney Damage: Drug-Induced	1	2
Lipopolysaccharide-Induced Toxicity	2	2
Lupus Erythematosus: Cutaneous	1	2
Myocardial Ischemia	1	2
Nonalcoholic fatty liver disease (NAFLD)	1	2
Periodontitis	1	2
Radiation Induced Illness: Enteritis	1	2
Scars	1	2
Sepsis	1	2
Skin Cancer: Prevention	1	2
Stress	1	2
Sunburn	1	2
Venous Ulcer	1	2
Wound Healing	1	2
Wound Healing: Delayed	1	2
Allergies	1	1
Anemia: Hemolytic	1	1
Brain Inflammation	1	1
Brain: Microglial Activation	1	1
Cancer Metastasis	1	1
Cancers: All	1	1
Enterococcus Infections	1	1
Epstein-Barr Virus Infections	1	1
Escherichia coli Infections	1	1
Gingivitis	1	1
Glucosephosphate Dehydrogenase Deficiency	1	1
Gout	1	1
HIV Infections	1	1
Hyperpigmentation	1	1
Liver Cancer	1	1
Low Human Growth Hormone	1	1
Lung Cancer	1	1
Oral Cancer	1	1
Ovarian Cancer	1	1
Pancreatic Cancer	1	1
Peroxynitrite Toxicity	1	1
Prostate Cancer	1	1
Pseudomonas aeruginosa	1	1
Sickle Cell Anemia	1	1
Squamous cell carcinoma	1	1
Staphylococcus aureus infection	1	1
Ultraviolet Radiation Induced Damage	1	1

63 Pharmacological Actions Researched for Pycnogenol (Pine Bark)

Name	AC	CK
Antioxidants	24	108
Platelet Aggregation Inhibitors	4	40
Antihypertensive Agents	3	30
Hypoglycemic Agents	3	22
Antineoplastic Agents	3	21
Fertility Agents: Male	2	20
Prophylactic Agents	2	20
Apoptotic	9	18
Anti-Inflammatory Agents	9	14
Antiproliferative	4	13
Matrix metalloproteinase-9 (MMP-9) inhibitor	4	13
NF-kappaB Inhibitor	4	13
Neuroprotective Agents	3	13
Cardioprotective	2	12
Heme oxygenase-1 up-regulation	2	11
Analgesics	1	10
Calcium Channel Blockers	1	10
Catalase Up-Regulation	1	10
Hypolipidemic	1	10
Malondialdehyde Down-regulation	4	8
Chemoprotective Agents	3	6
Antiviral Agents	4	5
Cytoprotective	1	5
Hepatoprotective	3	5
Anti-thrombotic	1	4
Glutathione Upregulation	2	4
Interleukin-4 downregulation	2	4
Renoprotective	2	4
Alpha-glucosidase inhibitor	2	3
Anti-Bacterial Agents	2	3
Anti-metastatic	3	3
Chemopreventive	2	3
Tumor Necrosis Factor (TNF) Alpha Inhibitor	2	3
Alpha-amylase inhibitor	1	2
Anti-Apoptotic	1	2
Anti-Ulcer Agents	1	2
Anti-atherogenic	1	2
Anticarcinogenic Agents	1	2
Antidepressive Agents	1	2
Bcl-2 protein down-regulation	2	2
Chemotherapeutic	2	2
Chondroprotective	1	2
DNA Repair Up-regulation	1	2
Immunomodulatory	1	2
Interleukin-1 beta downregulation	1	2
Interleukin-10 downregulation	1	2
Interleukin-5 downregulation	1	2
Radioprotective	1	2
Superoxide Dismutase Up-regulation	1	2
Vascular Endothelial Growth Factor Inhibitors	1	2
interleukin-13 down-regulation	1	2
Anti-HIV Agents	1	1
Antimicrobial	1	1
Cell cycle arrest	1	1
Cytotoxic	1	1
Enzyme Inhibitors	1	1
Gastrointestinal Agents	1	1
Histamine Antagonists	1	1
Matrix metalloproteinase-2 (MMP-2) inhibitor	1	1
Nitric Oxide Inhibitor	1	1
Photoprotective	1	1
Secretagogue	1	1
Xanthine oxidase inhibitor	1	1

Focused Research Articles 1
Cumulative Knowledge Score 1
Overall Research Rating GOOD

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View the Evidence:
1 Abstracts with Pycnogenol (Pine Bark)
& Brain: Microglial Activation Research

[x] Remove Focus on Brain: Microglial Activation

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Pycnogenol may be developed as a therapeutic agent for the treatment of neuroinflammatory diseases.Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2015 ;10(9):e0137837. Epub 2015 Sep 14. PMID: 26367267

Article Published Date : Dec 31, 2014

Study Type : In Vitro Study

Additional Links

Substances : Pycnogenol (Pine Bark)

Diseases : Brain: Microglial Activation, Brain Inflammation , Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor

Additional Keywords : Dose Response

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Focus Your Research

Click any topic below to filter + focus research

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View the Evidence: 1 Abstracts with Pycnogenol (Pine Bark) & Brain: Microglial Activation Research

Pycnogenol may be developed as a therapeutic agent for the treatment of neuroinflammatory diseases.Dec 31, 2014

Click here to read the entire abstract

Pycnogenol (Pine Bark) Related Articles

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Pycnogenol (Pine Bark) research focused on Brain: Microglial Activation

View the Evidence:
1 Abstracts with Pycnogenol (Pine Bark)
& Brain: Microglial Activation Research