Pycnogenol (Pine Bark) research focused on Apoptotic

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130 Diseases Researched for Pycnogenol (Pine Bark)
Oxidative Stress1044Locked
Erectile Dysfunction440Locked
Aging Skin330Locked
Diabetes Mellitus: Type 2422Locked
Asthma: Bronchial120Locked
Attention Deficit Disorder with Hyperactivity320Locked
Cognitive Decline/Dysfunction220Locked
Deep Vein Thrombosis220Locked
Diabetic Microangiopathy220Locked
Lower Urinary Tract Symptoms220Locked
Sperm Count: Low220Locked
Diabetes: Cardiovascular Illness214Locked
Sperm Quality: Low314Locked
Lipid Peroxidation212Locked
Radiation Induced Illness212Locked
Endothelial Dysfunction211Locked
Athletic Performance110Locked
Athletic Performance: Recovery 110Locked
Bladder Dysfunction 110Locked
Brain Edema110Locked
C-Reactive Protein110Locked
Cardiovascular Disease110Locked
Cardiovascular Disease: Prevention110Locked
Cardiovascular Diseases110Locked
Chronic Venous Insufficency110Locked
Common Cold110Locked
Elevated CRP110Locked
Fibrinogen: Elevated110Locked
Headache: Migraine110Locked
Homocysteine: Elevated110Locked
Hot Flash110Locked
Intermittent Claudication110Locked
Intraocular hypertension110Locked
Jet Lag110Locked
Kidney Diseases110Locked
Learning disorders110Locked
Lupus Erythematosus: Systemic110Locked
Menopausal Syndrome110Locked
Migraine Disorders110Locked
Perimenopausal Syndrome110Locked
Peripheral Arterial Disease110Locked
Premenopausal Disorders110Locked
Skin Diseases110Locked
Smoking: Cardiovascular Disease110Locked
Thromboembolism 110Locked
Varicose Veins: Postpartum110Locked
Cervical Cancer58Locked
Chemotherapy-Induced Toxicity: Cisplatin36Locked
Diabetes Mellitus: Type 135Locked
Chronic Obstructive Pulmonary Disease24Locked
Diabetic Amyotrophy14Locked
Diabetic Ulcer14Locked
Hepatitis C34Locked
Brain Injury: Traumatic23Locked
Allergic Rhinitis12Locked
Androgen Deficiency12Locked
Breast Cancer22Locked
Candida Infection 12Locked
Chemically-Induced Liver Damage12Locked
DNA damage12Locked
Fluoride Toxicity 12Locked
Hepatic Steatosis12Locked
Hydrogen Peroxide Induced Toxicity12Locked
Infertility: Male12Locked
Inflammatory Bowel Diseases12Locked
Kidney Damage: Drug-Induced12Locked
Lipopolysaccharide-Induced Toxicity22Locked
Lupus Erythematosus: Cutaneous12Locked
Myocardial Ischemia12Locked
Nonalcoholic fatty liver disease (NAFLD) 12Locked
Radiation Induced Illness: Enteritis12Locked
Skin Cancer: Prevention12Locked
Venous Ulcer12Locked
Wound Healing12Locked
Wound Healing: Delayed12Locked
Anemia: Hemolytic11Locked
Brain Inflammation 11Locked
Brain: Microglial Activation11Locked
Cancer Metastasis11Locked
Cancers: All11Locked
Enterococcus Infections11Locked
Epstein-Barr Virus Infections11Locked
Escherichia coli Infections11Locked
Glucosephosphate Dehydrogenase Deficiency11Locked
HIV Infections11Locked
Liver Cancer11Locked
Low Human Growth Hormone11Locked
Lung Cancer11Locked
Oral Cancer11Locked
Ovarian Cancer11Locked
Pancreatic Cancer11Locked
Peroxynitrite Toxicity11Locked
Prostate Cancer11Locked
Pseudomonas aeruginosa11Locked
Sickle Cell Anemia11Locked
Squamous cell carcinoma11Locked
Staphylococcus aureus infection11Locked
Ultraviolet Radiation Induced Damage11Locked
63 Pharmacological Actions Researched for Pycnogenol (Pine Bark)
Platelet Aggregation Inhibitors440Locked
Antihypertensive Agents330Locked
Hypoglycemic Agents322Locked
Antineoplastic Agents321Locked
Fertility Agents: Male220Locked
Prophylactic Agents220Locked
Anti-Inflammatory Agents914Locked
Antiproliferative 413Locked
Matrix metalloproteinase-9 (MMP-9) inhibitor413Locked
NF-kappaB Inhibitor413Locked
Neuroprotective Agents313Locked
Heme oxygenase-1 up-regulation211Locked
Calcium Channel Blockers110Locked
Catalase Up-Regulation110Locked
Malondialdehyde Down-regulation48Locked
Chemoprotective Agents36Locked
Antiviral Agents45Locked
Glutathione Upregulation 24Locked
Interleukin-4 downregulation24Locked
Alpha-glucosidase inhibitor 23Locked
Anti-Bacterial Agents23Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor23Locked
Alpha-amylase inhibitor12Locked
Anti-Ulcer Agents12Locked
Anticarcinogenic Agents12Locked
Antidepressive Agents12Locked
Bcl-2 protein down-regulation22Locked
DNA Repair Up-regulation12Locked
Interleukin-1 beta downregulation12Locked
Interleukin-10 downregulation12Locked
Interleukin-5 downregulation12Locked
Superoxide Dismutase Up-regulation12Locked
Vascular Endothelial Growth Factor Inhibitors12Locked
interleukin-13 down-regulation12Locked
Anti-HIV Agents11Locked
Cell cycle arrest11Locked
Enzyme Inhibitors11Locked
Gastrointestinal Agents11Locked
Histamine Antagonists11Locked
Matrix metalloproteinase-2 (MMP-2) inhibitor11Locked
Nitric Oxide Inhibitor11Locked
Xanthine oxidase inhibitor11Locked
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View the Evidence:
9 Abstracts with Pycnogenol (Pine Bark)
& Apoptotic Research

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Oncol. 2015 Apr ;46(4):1629-36. Epub 2015 Jan 27. PMID: 25625225
Study Type : Human Study
Additional Links
Diseases : Fibrosarcoma
Pubmed Data : J Complement Integr Med. 2011 Jan ;8(1). PMID: 22754951
Study Type : In Vitro Study
Additional Links
Diseases : Fibrosarcoma
Pharmacological Actions : Apoptotic
Pubmed Data : Prostate. 2008 Jul 28. PMID: 18663730
Study Type : In Vitro Study
Pubmed Data : Rev Med Chir Soc Med Nat Iasi. 2014 Apr-Jun;118(2):551-7. PMID: 25076730
Study Type : In Vitro Study
Additional Links
Diseases : Cervical Cancer
Pharmacological Actions : Apoptotic
Additional Keywords : Plant Extracts, Procyanidins
Pubmed Data : Phytother Res. 2008 Nov ;22(11):1472-6. PMID: 18803251
Study Type : In Vitro Study
Additional Links
Substances : Pine Bark Extract
Diseases : Cervical Cancer
Additional Keywords : Plant Extracts
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015 ;10(11):e0142157. Epub 2015 Nov 5. PMID: 26539720
Study Type : In Vitro Study
Pubmed Data : Cell Biol Toxicol. 2016 Jul 12. Epub 2016 Jul 12. PMID: 27400986
Study Type : In Vitro Study
Additional Links
Substances : Pine Bark Extract
Diseases : Breast Cancer
Pharmacological Actions : Apoptotic
Additional Keywords : Plant Extracts
Pubmed Data : Phytother Res. 2017 Nov ;31(11):1702-1707. Epub 2017 Aug 18. PMID: 28833790
Study Type : In Vitro Study
Additional Links
Pharmacological Actions : Apoptotic
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Biochem Nutr. 2016 Jan ;58(1):40-7. Epub 2015 Dec 8. PMID: 26798196
Study Type : In Vitro Study
Additional Links
Pharmacological Actions : Antiproliferative , Apoptotic, Chemopreventive
Additional Keywords : Dose Response

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Painful hemorrhoids, high blood pressure and skin issues, such as psoriasis, all have something in common: Blood flow. Research finds these three issues can all be successfully treated with the pine bark extract called Pycnogenol.
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Our aging skin is the target of billions of dollars worth of marketing, the object of a continual stream of cosmetics, drugs and 'nutraceuticals' promising to deliver age-defying results. But what really works? What does the scientific evidence say?
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Researchers from Japan's Keiju Medical Center have determined that a certain nutraceutical from pine trees can significantly reduce symptoms of menopause and perimenopause.
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When seasonal allergies strike they can bring with them a host of nasty symptoms including itchy and watery eyes, sneezing, a running nose and sore throat due to post-nasal drip. Medicating with anti-histamines isn’t a healthy option and can leave many feeling drowsy and fatigued. Luckily there are natural remedies that are making waves for their powerful anti-histamine-like effects and abilities to suppress seasonal allergy symptoms.
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Aspirin's long held promises are increasingly falling flat. A natural, safer and more effective alternative to this synthetic drug has been known about for at least 15 years!

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