Pycnogenol (Pine Bark) research focused on Chemotherapy-Induced Toxicity: Cisplatin

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130 Diseases Researched for Pycnogenol (Pine Bark)
NameACCKFocus
Hypertension770Locked
Oxidative Stress1044Locked
Osteoarthritis543Locked
Erectile Dysfunction440Locked
Inflammation533Locked
Aging Skin330Locked
Asthma323Locked
Atherosclerosis322Locked
Diabetes Mellitus: Type 2422Locked
Asthma: Bronchial120Locked
Attention Deficit Disorder with Hyperactivity320Locked
Cognitive Decline/Dysfunction220Locked
Deep Vein Thrombosis220Locked
Diabetic Microangiopathy220Locked
Glaucoma220Locked
Hemorrhoids220Locked
Lower Urinary Tract Symptoms220Locked
Melasma120Locked
Sperm Count: Low220Locked
Diabetes: Cardiovascular Illness214Locked
Sperm Quality: Low314Locked
Lipid Peroxidation212Locked
Psoriasis212Locked
Radiation Induced Illness212Locked
Endothelial Dysfunction211Locked
Fibrosarcoma211Locked
Athletic Performance110Locked
Athletic Performance: Recovery 110Locked
Bladder Dysfunction 110Locked
Brain Edema110Locked
C-Reactive Protein110Locked
CRP110Locked
Cardiovascular Disease110Locked
Cardiovascular Disease: Prevention110Locked
Cardiovascular Diseases110Locked
Chemotherapy110Locked
Chronic Venous Insufficency110Locked
Common Cold110Locked
Dysmenorrhea110Locked
Edema110Locked
Elevated CRP110Locked
Fibrinogen: Elevated110Locked
Headache: Migraine110Locked
Homocysteine: Elevated110Locked
Hot Flash110Locked
Intermittent Claudication110Locked
Intraocular hypertension110Locked
Jet Lag110Locked
Kidney Diseases110Locked
Learning disorders110Locked
Lupus Erythematosus: Systemic110Locked
Menopausal Syndrome110Locked
Microangiopathy110Locked
Migraine Disorders110Locked
Perimenopausal Syndrome110Locked
Peripheral Arterial Disease110Locked
Premenopausal Disorders110Locked
Skin Diseases110Locked
Smoking: Cardiovascular Disease110Locked
Thromboembolism 110Locked
Thrombophlebitis110Locked
Varicose Veins: Postpartum110Locked
Cervical Cancer58Locked
Chemotherapy-Induced Toxicity: Cisplatin36Locked
Diabetes Mellitus: Type 135Locked
Aging14Locked
Chronic Obstructive Pulmonary Disease24Locked
Diabetic Amyotrophy14Locked
Diabetic Ulcer14Locked
Hepatitis C34Locked
Thrombosis14Locked
Brain Injury: Traumatic23Locked
Obesity23Locked
Allergic Rhinitis12Locked
Androgen Deficiency12Locked
Breast Cancer22Locked
Candida Infection 12Locked
Cataract12Locked
Chemically-Induced Liver Damage12Locked
DNA damage12Locked
Depression12Locked
Dermatitis12Locked
Fluoride Toxicity 12Locked
Hepatic Steatosis12Locked
Hydrogen Peroxide Induced Toxicity12Locked
Hyperglycemia12Locked
Infertility: Male12Locked
Inflammatory Bowel Diseases12Locked
Kidney Damage: Drug-Induced12Locked
Lipopolysaccharide-Induced Toxicity22Locked
Lupus Erythematosus: Cutaneous12Locked
Myocardial Ischemia12Locked
Nonalcoholic fatty liver disease (NAFLD) 12Locked
Periodontitis12Locked
Radiation Induced Illness: Enteritis12Locked
Scars12Locked
Sepsis12Locked
Skin Cancer: Prevention12Locked
Stress12Locked
Sunburn12Locked
Venous Ulcer12Locked
Wound Healing12Locked
Wound Healing: Delayed12Locked
Allergies11Locked
Anemia: Hemolytic11Locked
Brain Inflammation 11Locked
Brain: Microglial Activation11Locked
Cancer Metastasis11Locked
Cancers: All11Locked
Enterococcus Infections11Locked
Epstein-Barr Virus Infections11Locked
Escherichia coli Infections11Locked
Gingivitis11Locked
Glucosephosphate Dehydrogenase Deficiency11Locked
Gout11Locked
HIV Infections11Locked
Hyperpigmentation11Locked
Liver Cancer11Locked
Low Human Growth Hormone11Locked
Lung Cancer11Locked
Oral Cancer11Locked
Ovarian Cancer11Locked
Pancreatic Cancer11Locked
Peroxynitrite Toxicity11Locked
Prostate Cancer11Locked
Pseudomonas aeruginosa11Locked
Sickle Cell Anemia11Locked
Squamous cell carcinoma11Locked
Staphylococcus aureus infection11Locked
Ultraviolet Radiation Induced Damage11Locked
63 Pharmacological Actions Researched for Pycnogenol (Pine Bark)
NameACCKFocus
Antioxidants24108Locked
Platelet Aggregation Inhibitors440Locked
Antihypertensive Agents330Locked
Hypoglycemic Agents322Locked
Antineoplastic Agents321Locked
Fertility Agents: Male220Locked
Prophylactic Agents220Locked
Apoptotic918Locked
Anti-Inflammatory Agents914Locked
Antiproliferative 413Locked
Matrix metalloproteinase-9 (MMP-9) inhibitor413Locked
NF-kappaB Inhibitor413Locked
Neuroprotective Agents313Locked
Cardioprotective212Locked
Heme oxygenase-1 up-regulation211Locked
Analgesics110Locked
Calcium Channel Blockers110Locked
Catalase Up-Regulation110Locked
Hypolipidemic110Locked
Malondialdehyde Down-regulation48Locked
Chemoprotective Agents36Locked
Antiviral Agents45Locked
Cytoprotective15Locked
Hepatoprotective35Locked
Anti-thrombotic14Locked
Glutathione Upregulation 24Locked
Interleukin-4 downregulation24Locked
Renoprotective24Locked
Alpha-glucosidase inhibitor 23Locked
Anti-Bacterial Agents23Locked
Anti-metastatic33Locked
Chemopreventive23Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor23Locked
Alpha-amylase inhibitor12Locked
Anti-Apoptotic12Locked
Anti-Ulcer Agents12Locked
Anti-atherogenic12Locked
Anticarcinogenic Agents12Locked
Antidepressive Agents12Locked
Bcl-2 protein down-regulation22Locked
Chemotherapeutic22Locked
Chondroprotective12Locked
DNA Repair Up-regulation12Locked
Immunomodulatory12Locked
Interleukin-1 beta downregulation12Locked
Interleukin-10 downregulation12Locked
Interleukin-5 downregulation12Locked
Radioprotective12Locked
Superoxide Dismutase Up-regulation12Locked
Vascular Endothelial Growth Factor Inhibitors12Locked
interleukin-13 down-regulation12Locked
Anti-HIV Agents11Locked
Antimicrobial11Locked
Cell cycle arrest11Locked
Cytotoxic11Locked
Enzyme Inhibitors11Locked
Gastrointestinal Agents11Locked
Histamine Antagonists11Locked
Matrix metalloproteinase-2 (MMP-2) inhibitor11Locked
Nitric Oxide Inhibitor11Locked
Photoprotective11Locked
Secretagogue11Locked
Xanthine oxidase inhibitor11Locked
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View the Evidence:
4 Abstracts with Pycnogenol (Pine Bark)
& Chemotherapy-Induced Toxicity: Cisplatin Research

[+]

Pine bark extract has a cytoprotective effect against oxidative stress-mediated apoptotic changes caused by cisplatin in the rat kidney.Oct 31, 2017

Pubmed Data : Ren Fail. 2017 Nov ;39(1):363-371. PMID: 28178874
Article Published Date : Oct 31, 2017
Study Type : Animal Study
Additional Links
Substances : Pine Bark Extract
Diseases : Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions : Chemoprotective Agents, Renoprotective
[+]

Pycnogenol had a protective effect against acute hepatotoxicity induced by cisplatin.Nov 30, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Lab Anim Res. 2014 Dec ;30(4):174-80. Epub 2014 Dec 24. PMID: 25628728
Article Published Date : Nov 30, 2014
Study Type : Animal Study
Additional Links
Substances : Pycnogenol (Pine Bark)
Diseases : Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions : Antioxidants, Chemoprotective Agents, Hepatoprotective, Malondialdehyde Down-regulation
[+]

Pycnogenol pre-treatment was highly effective in preventing augmentation of cisplatin induced oxidative stress and inflammation in eye tissue.Jul 02, 2018

Pubmed Data : Cutan Ocul Toxicol. 2018 Jul 3:1-13. Epub 2018 Jul 3. PMID: 29969298
Article Published Date : Jul 02, 2018
Study Type : Animal Study
Additional Links
Substances : Pycnogenol (Pine Bark)
Diseases : Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Chemoprotective Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Pycnogenol protected against cisplatin ototoxicity. Oct 31, 2016

Pubmed Data : Pharm Biol. 2016 Nov ;54(11):2777-2781. Epub 2016 May 9. PMID: 27158843
Article Published Date : Oct 31, 2016
Study Type : Animal Study
Additional Links
Substances : Pycnogenol (Pine Bark)
Diseases : Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions : Chemoprotective Agents

Copyright: jteivans / 123RF Stock Photo

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