Red Wine Extract

Red Wine Extract

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View the Evidence: Substances

Among patients with established heart disease, moderate consumption of wine seems to be associated with lower incidence of cardiovascular events and total mortality as compared with non drinkers.

Pubmed Data : Int J Cardiol. 2011 Jul 5. Epub 2011 Jul 5. PMID: 21737162
Article Published Date : Jul 05, 2011
Study Type : Human Study
Additional Links
Substances : Red Wine Extract : CK(59) : AC(25), Wine : CK(132) : AC(35)
Diseases : Cardiac Mortality : CK(703) : AC(67), Cardiovascular Diseases : CK(5138) : AC(641), Mortality: All-Cause : CK(644) : AC(55)

Beer, vodka and especially red wine prevent oxygen-induced oxidative stress associated with arterial stiffness.

Pubmed Data : Atherosclerosis. 2011 Jul 12. Epub 2011 Jul 12. PMID: 21803358
Article Published Date : Jul 12, 2011
Study Type : Human Study
Additional Links
Substances : Alcohol : CK(82) : AC(9), Beer : CK(37) : AC(8), Red Wine Extract : CK(59) : AC(25)
Diseases : Arterial Hardening: Elasticity : CK(128) : AC(17), Hyperoxia : CK(10) : AC(1)
Pharmacological Actions : Vasodilator Agents : CK(262) : AC(54)

The moderate consumption of red wine provides cardiovascular protection.

Pubmed Data : Am J Clin Nutr. 2010 Jul;92(1):161-9. Epub 2010 Apr 14. PMID: 20392892
Article Published Date : Jul 01, 2010
Study Type : Human Study
Additional Links
Substances : Red Wine Extract : CK(59) : AC(25)
Diseases : Cardiovascular Diseases : CK(5138) : AC(641), Endothelial Dysfunction : CK(897) : AC(173)

Moderate ethanol and quercetin, the two major components of red wine, exhibit cardioprotective properties via the up-regulation of the antiatherogenic gene PON1.

Pubmed Data : Genes Nutr. 2009 Dec 13. PMID: 20012900
Article Published Date : Dec 13, 2009
Study Type : Animal Study
Additional Links
Substances : Alcohol : CK(82) : AC(9), Quercetin : CK(318) : AC(136), Red Wine Extract : CK(59) : AC(25)
Diseases : Cardiovascular Diseases : CK(5138) : AC(641)
Pharmacological Actions : Cardioprotective : CK(702) : AC(196)

Red wine intake (resveratrol) may protect against oxLDL-induced dysfunction of endothelial cells.

Pubmed Data : Clin Chim Acta. 2006 Feb;364(1-2):196-204. Epub 2005 Aug 10. PMID: 16095586
Article Published Date : Feb 01, 2006
Study Type : Animal Study
Additional Links
Substances : Red Wine Extract : CK(59) : AC(25), Resveratrol : CK(977) : AC(590)
Diseases : Cholesterol: Oxidation : CK(457) : AC(98), Endothelial Damage : CK(31) : AC(10), Endothelial Dysfunction : CK(897) : AC(173)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Cardioprotective : CK(702) : AC(196)
Additional Keywords : Stilbenes : CK(402) : AC(242)

Red wine polyphenols may prevent endothelial dysfunction.

Pubmed Data : Clin Sci (Lond). 2011 Apr 1;120(8):321-33. PMID: 20977430
Article Published Date : Apr 01, 2011
Study Type : Animal Study
Additional Links
Substances : Red Wine Extract : CK(59) : AC(25), Resveratrol : CK(977) : AC(590)
Diseases : Endothelial Dysfunction : CK(897) : AC(173)

Red wine polyphenols prevent hypertension and endothelial dysfunction in rats.

Pubmed Data : Cardiovasc Res. 2006 Sep 1;71(4):794-802. Epub 2006 May 26. PMID: 16822492
Article Published Date : Sep 01, 2006
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(909) : AC(289), Polyphenols : CK(427) : AC(174), Red Wine Extract : CK(59) : AC(25)
Diseases : Endothelial Dysfunction : CK(897) : AC(173), Hypertension : CK(2783) : AC(271)
Pharmacological Actions : Cardioprotective : CK(702) : AC(196), Vasodilator Agents : CK(262) : AC(54)

Red wine polyphenols protect and reverse liver fibrosis in mice with elevated homocysteine.

Pubmed Data : J Nutr Biochem. 2010 Dec 23. Epub 2010 Dec 23. PMID: 21185709
Article Published Date : Dec 23, 2010
Study Type : Animal Study
Additional Links
Substances : Polyphenols : CK(427) : AC(174), Red Wine Extract : CK(59) : AC(25)
Diseases : High Homocysteine : CK(368) : AC(57), Liver Fibrosis : CK(341) : AC(74)
Pharmacological Actions : Cardioprotective : CK(702) : AC(196)

Resveratrol and red wine function as antioxidants in the nervous system without cellular proliferative effects during experimental diabetes.

Pubmed Data : Oxid Med Cell Longev. 2010 Nov 1;3(6):434-41. Epub 2010 Nov 1. PMID: 21307644
Article Published Date : Nov 01, 2010
Study Type : Animal Study
Additional Links
Substances : Red Wine Extract : CK(59) : AC(25), Resveratrol : CK(977) : AC(590)
Diseases : Brain Injury: Hippocampal Damage : CK(35) : AC(16), Diabetes: Oxidative Stress : CK(65) : AC(18)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

The red wine antioxidant resveratrol may be useful for the regeneration of infaracted myocardium.

Pubmed Data : J Cell Mol Med. 2010 Sep;14(9):2235-9. PMID: 20716127
Article Published Date : Sep 01, 2010
Study Type : Animal Study
Additional Links
Substances : Red Wine Extract : CK(59) : AC(25), Resveratrol : CK(977) : AC(590)
Diseases : Myocardial Infarction : CK(2632) : AC(117)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Neocardiogenic : CK(8) : AC(7), Regenerative : CK(9) : AC(3)
Additional Keywords : Myocardial Regeneration : CK(10) : AC(7), Stilbenes : CK(402) : AC(242)

A variety of phenolic compounds from grapes/red wine exhibit antioxidant properties.

Pubmed Data : Prostaglandins Leukot Essent Fatty Acids. 2004 Jun;70(6):521-8. PMID: 9395251
Article Published Date : Jun 01, 2004
Study Type : In Vitro Study
Additional Links
Substances : Astringinin : CK(1) : AC(1), Grape : CK(998) : AC(274), Red Wine Extract : CK(59) : AC(25), Resveratrol : CK(977) : AC(590), Stilbenes : CK(128) : AC(92)
Diseases : Lipid Peroxidation : CK(403) : AC(127), Oxidative Stress : CK(1945) : AC(710)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

Grape and wine extracts have antibacterial activity against Helicobacter pylori clinical isolates.

Pubmed Data : J Chemother. 2009 Nov;21(5):507-13. PMID: 19933041
Article Published Date : Nov 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids : CK(909) : AC(289), Grape : CK(998) : AC(274), Polyphenols : CK(427) : AC(174), Red Wine Extract : CK(59) : AC(25), Wine : CK(132) : AC(35)
Diseases : Helicobacter Pylori Infection : CK(305) : AC(61)
Pharmacological Actions : Anti-Bacterial Agents : CK(970) : AC(316), Antioxidants : CK(3653) : AC(1318)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Grape seed extract, red wine and especially diosmin, inhibit pulmonary metastatic melanoma.

Pubmed Data : Histol Histopathol. 2005 Oct;20(4):1121-9. PMID: 16136495
Article Published Date : Oct 01, 2005
Study Type : In Vitro Study
Additional Links
Substances : Diosmin : CK(184) : AC(31), Grape Seed Extract : CK(168) : AC(57), Red Wine Extract : CK(59) : AC(25)
Diseases : Lung Cancer : CK(496) : AC(198), Melanoma: Metastatic : CK(21) : AC(13), Pulmonary Cancer : CK(8) : AC(5)

Lignin-derived oak phenolics, although found in small concentrations, may contribute to the beneficial antioxidant, chemopreventive, and cardioprotective effects of red wine.

Pubmed Data : J Mol Model. 2010 Nov 16. Epub 2010 Nov 16. PMID: 21080014
Article Published Date : Nov 16, 2010
Study Type : In Vitro Study
Additional Links
Substances : Lignans : CK(110) : AC(31), Oak : CK(5) : AC(4), Polyphenols : CK(427) : AC(174), Red Wine Extract : CK(59) : AC(25), Wine : CK(132) : AC(35)
Diseases : Cancers: All : CK(9062) : AC(2869), Cardiovascular Diseases : CK(5138) : AC(641)
Pharmacological Actions : Chemopreventive : CK(1528) : AC(382)

Nutritional interventions may be therapeutic in the treatment of amyotrophic lateral sclerosis.

Pubmed Data : Clin Nutr. 2009 Dec;28(6):604-17. Epub 2009 Sep 25. PMID: 19782443
Article Published Date : Dec 01, 2009
Study Type : Commentary
Additional Links
Substances : Alpha-Lipoic Acid : CK(384) : AC(82), Carnitine : CK(672) : AC(69), Coenzyme Q10 : CK(667) : AC(104), EGCG (Epigallocatechin gallate) : CK(859) : AC(109), Folic Acid : CK(542) : AC(77), Ginkgo biloba : CK(512) : AC(97), Melatonin : CK(470) : AC(131), Red Wine Extract : CK(59) : AC(25), Vitamin E : CK(1285) : AC(221)
Diseases : Amyotrophic Lateral Sclerosis : CK(350) : AC(68)

Olive oil and red wine antioxidant polyphenols at nutritionally relevant concentrations transcriptionally inhibit endothelial adhesion molecule expression, thus partially explaining atheroprotection from Mediterranean diets.

Pubmed Data : Arterioscler Thromb Vasc Biol. 2003 Apr 1;23(4):622-9. Epub 2003 Feb 20. PMID: 12615669
Article Published Date : Apr 01, 2003
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids : CK(909) : AC(289), Oleuropein : CK(51) : AC(32), Olive : CK(401) : AC(97), Polyphenols : CK(427) : AC(174), Red Wine Extract : CK(59) : AC(25), Resveratrol : CK(977) : AC(590), Tyrosol : CK(3) : AC(3)
Diseases : Arteriosclerosis : CK(2154) : AC(123), Endothelial Dysfunction : CK(897) : AC(173)
Therapeutic Actions : Dietary Modification: Mediterranean Diet : CK(500) : AC(58)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), NF-kappaB Inhibitor : CK(595) : AC(401), Vascular Cell Adhesion Molecule-1 Inhibitor : CK(94) : AC(24)

Procyandidin from Red Wine and Grape Seeds inhibit androgen-dependant breast cancer turmors by reducing estrogen formation.

Pubmed Data : Cancer Res. 2003 Dec 1;63(23):8516-22. PMID: 14679019
Article Published Date : Dec 01, 2003
Study Type : In Vitro Study
Additional Links
Substances : Grape Seed Extract : CK(168) : AC(57), Red Wine Extract : CK(59) : AC(25)
Diseases : Breast Cancer : CK(2354) : AC(621)
Pharmacological Actions : Aromatase Inhibitors : CK(33) : AC(23)

Red wine and resveratrol have anti-platelet properties.

Pubmed Data : Int J Tissue React. 1995;17(1):1-3. PMID: 7499059
Article Published Date : Jan 01, 1995
Study Type : In Vitro Study
Additional Links
Substances : Red Wine Extract : CK(59) : AC(25), Resveratrol : CK(977) : AC(590), Stilbenes : CK(128) : AC(92)
Diseases : Thrombosis : CK(657) : AC(74)
Pharmacological Actions : Platelet Aggregation Inhibitors : CK(173) : AC(37)

Red wine extract has anti-aromatase activity which abrogates hyperpasia in mammary tissue.

Pubmed Data : Breast Cancer Res Treat. 2001 May;67(2):133-46. PMID: 11519862
Article Published Date : May 01, 2001
Study Type : In Vitro Study
Additional Links
Substances : Red Wine Extract : CK(59) : AC(25)
Diseases : Breast Cancer : CK(2354) : AC(621)
Pharmacological Actions : Aromatase Inhibitors : CK(33) : AC(23)

Red wine polyphenols cause growth inhibition and programmed cell death in acute lymphoblastic leukaemia cells.

Pubmed Data : Eur J Cancer. 2010 Mar;46(5):983-94. Epub 2010 Jan 13. PMID: 20074931
Article Published Date : Mar 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids : CK(909) : AC(289), Polyphenols : CK(427) : AC(174), Red Wine Extract : CK(59) : AC(25)
Diseases : Acute lymphoblastic leukemia (ALL) : CK(96) : AC(29)
Pharmacological Actions : Antiproliferative : CK(1052) : AC(775), Apoptotic : CK(1489) : AC(1114), Cell cycle arrest : CK(390) : AC(319)

Red wine polyphenols contribute to nitric oxide production in the lining of the arteries.

Pubmed Data : FASEB J. 2005 Mar;19(3):455-7. Epub 2004 Dec 28. PMID: 15623569
Article Published Date : Mar 01, 2005
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids : CK(909) : AC(289), Polyphenols : CK(427) : AC(174), Red Wine Extract : CK(59) : AC(25)
Diseases : Endothelial Dysfunction : CK(897) : AC(173)
Pharmacological Actions : Nitric Oxide Enhancer : CK(149) : AC(37)

Red wine polyphenols prevent cyclosporine-induced nephrotoxicity at the level of the intrinsic apoptotic pathway.

Pubmed Data : Physiol Res. 2009;58(4):511-9. Epub 2008 Jul 25. PMID: 18656999
Article Published Date : Jan 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids : CK(909) : AC(289), Polyphenols : CK(427) : AC(174), Red Wine Extract : CK(59) : AC(25)
Diseases : Hypertension : CK(2783) : AC(271), Kidney Damage: Drug-Induced : CK(86) : AC(22), Oxidative Stress : CK(1945) : AC(710)
Pharmacological Actions : Apoptotic : CK(1489) : AC(1114), Renoprotective : CK(191) : AC(90)

Resveratrol's therapeutic properties in neurodegenerative conditions may be due to its gene protective and regulatory as well as antioxidant properties.

Pubmed Data : Neuropharmacology. 2008 Jun;54(7):1112-9. Epub 2008 Mar 16. PMID: 15956815
Article Published Date : Jun 01, 2008
Study Type : Review
Additional Links
Substances : Flavonoids : CK(909) : AC(289), Polyphenols : CK(427) : AC(174), Red Wine Extract : CK(59) : AC(25), Resveratrol : CK(977) : AC(590), Wine : CK(132) : AC(35)
Diseases : Alzheimer's Disease : CK(826) : AC(160), Amyotrophic Lateral Sclerosis : CK(350) : AC(68), Brain Inflammation : CK(79) : AC(35), Neurodegenerative Diseases : CK(1743) : AC(420), Oxidative Stress : CK(1945) : AC(710), Parkinson Disease : CK(543) : AC(79)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Neuroprotective Agents : CK(962) : AC(480)
Additional Keywords : Stilbenes : CK(402) : AC(242)

Trans-resveratrol, an extract of red wine, inhibits human eosinophil activation and degranulation associated with eosinophil-related allergic diseases.

Pubmed Data : Br J Pharmacol. 2008 Dec;155(7):995-1004. Epub 2008 Sep 8. PMID: 18776917
Article Published Date : Dec 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Red Wine Extract : CK(59) : AC(25), Resveratrol : CK(977) : AC(590)
Diseases : Allergies : CK(502) : AC(92)
Pharmacological Actions : Anti-Allergic Agents : CK(89) : AC(38), Apoptotic : CK(1489) : AC(1114)
Additional Keywords : Stilbenes : CK(402) : AC(242)

Wine polyphenolic extracts have a cytotoxic effect against human cancer cell lines.

Pubmed Data : J Med Food. 2010 Aug;13(4):851-62. PMID: 20482276
Article Published Date : Aug 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids : CK(909) : AC(289), Polyphenols : CK(427) : AC(174), Red Wine Extract : CK(59) : AC(25), Resveratrol : CK(977) : AC(590), Wine : CK(132) : AC(35)
Diseases : Breast Cancer : CK(2354) : AC(621), Cervical Cancer : CK(363) : AC(69)
Pharmacological Actions : Apoptotic : CK(1489) : AC(1114)
Additional Keywords : Stilbenes : CK(402) : AC(242)

Related Blogs

Can't Get To The Gym? Have A Glass of Red Wine
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It may sound like a dream come true for many of us, but a research study published in the FASEB Journal, suggests that resveratrol, the healthy compound found in red wine, could help counter the negative effects of being a couch potato.
A Traditional Thanksgiving Deserves a Heritage Turkey
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Ideally, this Thanksgiving you are ordering your organic, free-range turkey from your local farmer. It doesn't get any better than that does it? Actually, it does. Farmers markets are now featuring "Heritage Turkeys" for those wanting an even more authentic Thanksgiving dinner.

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