Resveratrol

Resveratrol

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View the Evidence: Substances

Dosage Study: Resveratrol has variable effects depending on the dose used.

Pubmed Data : Dose Response. 2010;8(4):478-500. Epub 2010 Mar 18. PMID: 21191486
Article Published Date : Jan 01, 2010
Study Type : Meta Analysis
Additional Links
Substances : Resveratrol : CK(977) : AC(590)

Resveratrol has a neuroprotective effect in a rat model of aging.

Pubmed Data : Mol Cells. 2008 Nov 30;26(5):486-9. PMID: 21122283
Article Published Date : Nov 30, 2008
Study Type : Meta Analysis
Additional Links
Substances : Resveratrol : CK(977) : AC(590)
Diseases : Aging : CK(1351) : AC(369), Aging: Brain : CK(1747) : AC(68), Oxidative Stress : CK(1945) : AC(710)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Neuroprotective Agents : CK(962) : AC(480)
Additional Keywords : Stilbenes : CK(402) : AC(242)

Acute resveratrol supplementation improves flow-mediated dilatation in overweight/obese individuals with mildly elevated blood pressure.

Pubmed Data : Nutr Metab Cardiovasc Dis. 2010 Jul 29. Epub 2010 Jul 29. PMID: 20674311
Article Published Date : Jul 29, 2010
Study Type : Human Study
Additional Links
Substances : Resveratrol : CK(977) : AC(590)
Diseases : Hypertension : CK(2783) : AC(271), Obesity : CK(1849) : AC(275), Overweight : CK(2176) : AC(342)
Pharmacological Actions : Hypotensive : CK(383) : AC(53), Vasodilator Agents : CK(262) : AC(54)

An antiinflammatory dietary mix modulates inflammation and oxidative and metabolic stress in overweight men.

Pubmed Data : Am J Clin Nutr. 2010 Apr;91(4):1044-59. Epub 2010 Feb 24. PMID: 20181810
Article Published Date : Apr 01, 2010
Study Type : Human Study
Additional Links
Substances : Green Tea : CK(930) : AC(294), Omega-3 Fatty Acids : CK(3333) : AC(319), Resveratrol : CK(977) : AC(590), Tomato : CK(271) : AC(47), Vitamin C : CK(1274) : AC(238), Vitamin E : CK(1285) : AC(221)
Diseases : Adiponectin: Low Levels : CK(88) : AC(25), Endothelial Dysfunction : CK(897) : AC(173), Inflammation : CK(1077) : AC(363), Oxidative Stress : CK(1945) : AC(710)
Pharmacological Actions : Anti-Inflammatory Agents : CK(1230) : AC(433), Antioxidants : CK(3653) : AC(1318)

Chronic daily consumption of a resveratrol-containing grape nutraceutical could exert cardiovascular benefits in stable-CAD patients.

Pubmed Data : Cardiovasc Drugs Ther. 2012 Dec 8. Epub 2012 Dec 8. PMID: 23224687
Article Published Date : Dec 07, 2012
Study Type : Human Study
Additional Links
Substances : Resveratrol : CK(977) : AC(590)
Diseases : Adiponectin: Low Levels : CK(88) : AC(25), Coronary Artery Disease : CK(1305) : AC(136)
Pharmacological Actions : Anti-Inflammatory Agents : CK(1230) : AC(433), Cardioprotective : CK(702) : AC(196)

Oral resveratrol and calcium fructoborate supplementation has therapeutic value in subjects with stable angina pectoris.

Pubmed Data : Nutrition. 2013 Jan ;29(1):178-83. Epub 2012 Nov 13. PMID: 23153742
Article Published Date : Dec 31, 2012
Study Type : Human Study
Additional Links
Substances : Fructoborate : CK(10) : AC(1), Resveratrol : CK(977) : AC(590)
Diseases : Angina Pectoris : CK(93) : AC(11)

Polygonum cuspidatum, a natural source of resveratrol, has antioxidant and anti-inflammatory activity.

Pubmed Data : J Clin Endocrinol Metab. 2010 Sep;95(9):E1-8. Epub 2010 Jun 9. PMID: 20534755
Article Published Date : Sep 01, 2010
Study Type : Human Study
Additional Links
Substances : Resveratrol : CK(977) : AC(590)
Diseases : Inflammation : CK(1077) : AC(363), Oxidative Stress : CK(1945) : AC(710)
Pharmacological Actions : Anti-Inflammatory Agents : CK(1230) : AC(433), Antioxidants : CK(3653) : AC(1318)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216), Stilbenes : CK(402) : AC(242)

Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the Akt pathway in type 2 diabetic patients.

Pubmed Data : Br J Nutr. 2011 Mar 9:1-7. Epub 2011 Mar 9. PMID: 21385509
Article Published Date : Mar 09, 2011
Study Type : Human Study
Additional Links
Substances : Resveratrol : CK(977) : AC(590)
Diseases : Diabetes: Oxidative Stress : CK(65) : AC(18), Diabetes Mellitus: Type 2 : CK(3429) : AC(341), Insulin Resistance : CK(1034) : AC(221)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Insulin Receptor Modulator : CK(12) : AC(2)

Resveratrol inhibits cellular oxidative stress in monocytes cultured from type 1 diabetic patients

Pubmed Data : J Nutr Biochem. 2011 Aug 1. Epub 2011 Aug 1. PMID: 21813271
Article Published Date : Aug 01, 2011
Study Type : Human Study
Additional Links
Substances : Resveratrol : CK(977) : AC(590)
Diseases : Diabetes Mellitus: Type 1 : CK(1107) : AC(218)

Resveratrol inhibits the formation of membrane protein carbonyls and lipid peroxidation in erythrocytes subjected to oxidative stress.

Pubmed Data : Appl Physiol Nutr Metab. 2009 Dec;34(6):1093-7. PMID: 20029519
Article Published Date : Dec 01, 2009
Study Type : Human Study
Additional Links
Substances : Resveratrol : CK(977) : AC(590), Stilbenes : CK(128) : AC(92)
Diseases : Lipid Peroxidation : CK(403) : AC(127), Oxidative Stress : CK(1945) : AC(710)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Malondialdehyde Down-regulation : CK(76) : AC(21)

Resveratrol may positively modulate cerebral blood flow variables.

Pubmed Data : Am J Clin Nutr. 2010 Jun;91(6):1590-7. Epub 2010 Mar 31. PMID: 20357044
Article Published Date : Jun 01, 2010
Study Type : Human Study
Additional Links
Substances : Resveratrol : CK(977) : AC(590)
Diseases : Brain Diseases : CK(17) : AC(6), Brain Ischemia : CK(94) : AC(38)
Pharmacological Actions : Vasodilator Agents : CK(262) : AC(54)
Additional Keywords : Stilbenes : CK(402) : AC(242)

Resveratrol modulates drug- and carcinogen-metabolizing enzymes in a healthy volunteer study.

Pubmed Data : Cancer Prev Res (Phila). 2010 Sep;3(9):1168-75. Epub 2010 Aug 17. PMID: 20716633
Article Published Date : Sep 01, 2010
Study Type : Human Study
Additional Links
Substances : Resveratrol : CK(977) : AC(590)
Diseases : Cancers: All : CK(9062) : AC(2869), Drug-Induced Toxicity : CK(560) : AC(78)
Pharmacological Actions : Chemopreventive : CK(1528) : AC(382), Detoxifier : CK(306) : AC(101)
Additional Keywords : Stilbenes : CK(402) : AC(242)

Resveratrol protects against alcohol-induced oxidative DNA damage in human peripheral lymphocytes.

Pubmed Data : HIV Med. 2010 Jan 5. Epub 2010 Jan 5. PMID: 21281738
Article Published Date : Jan 05, 2010
Study Type : Human Study
Additional Links
Substances : Resveratrol : CK(977) : AC(590)
Diseases : Alcohol Toxicity : CK(212) : AC(85), DNA damage : CK(711) : AC(293), Oxidative Stress : CK(1945) : AC(710)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Genoprotective : CK(116) : AC(48)

Resveratrol reduces insulin-like growth factor levels in healthy volunteers, indicating it may have chemopreventive properties.

Pubmed Data : Biochem Biophys Res Commun. 2010 Apr 2;394(2):360-5. Epub 2010 Mar 6. PMID: 20935227
Article Published Date : Apr 02, 2010
Study Type : Human Study
Additional Links
Substances : Resveratrol : CK(977) : AC(590)
Diseases : Cancers: All : CK(9062) : AC(2869), Insulin-like Growth Factor (IGF): Elevated : CK(33) : AC(6)
Pharmacological Actions : Insulin-Like Growth Factor Inhibition/Downregulation : CK(66) : AC(16)
Additional Keywords : Stilbenes : CK(402) : AC(242)

Resveratrol reduces tumor cell proliferation in colorectal patients.

Pubmed Data : Antiviral Res. 2008 Feb;77(2):153-6. Epub 2007 Oct 8. PMID: 20841478
Article Published Date : Feb 01, 2008
Study Type : Human Study
Additional Links
Substances : Resveratrol : CK(977) : AC(590)
Diseases : Colorectal Cancer : CK(877) : AC(321)
Pharmacological Actions : Antiproliferative : CK(1052) : AC(775)
Additional Keywords : Stilbenes : CK(402) : AC(242)

Resveratrol suppresses oxidative and inflammatory stress associated with a high-fat, high-carbohydrate diet.

Pubmed Data : J Clin Endocrinol Metab. 2011 Feb 2. Epub 2011 Feb 2. PMID: 21289251
Article Published Date : Feb 02, 2011
Study Type : Human Study
Additional Links
Substances : Resveratrol : CK(977) : AC(590)
Diseases : Inflammation : CK(1077) : AC(363), Oxidative Stress : CK(1945) : AC(710)
Pharmacological Actions : Anti-Inflammatory Agents : CK(1230) : AC(433), Antioxidants : CK(3653) : AC(1318)

Safety & Dosage Review: Resveratrol.

Pubmed Data : Clin Pharmacokinet. 2010 Jul 1;49(7):449-54. PMID: 20528005
Article Published Date : Jul 01, 2010
Study Type : Human Study
Additional Links
Substances : Resveratrol : CK(977) : AC(590)
Additional Keywords : Stilbenes : CK(402) : AC(242)

Topical resveratrol results in a significant decrease in acne associated lesions.

Pubmed Data : Am J Clin Dermatol. 2011 Apr 1;12(2):133-41. PMID: 21348544
Article Published Date : Apr 01, 2011
Study Type : Human Study
Additional Links
Substances : Resveratrol : CK(977) : AC(590)
Diseases : Acne : CK(198) : AC(32)

Resveratrol has a chemoprevention effect in chemically-Induced hepatocarcinogenesis.

Pubmed Data : Curr Pharm Biotechnol. 2011 Apr 5. Epub 2011 Apr 5. PMID: 21466437
Article Published Date : Apr 05, 2011
Study Type : Animal Study
Additional Links
Substances : Resveratrol : CK(977) : AC(590)
Diseases : Liver Cancer: Prevention : CK(109) : AC(21)
Pharmacological Actions : Chemopreventive : CK(1528) : AC(382)

Resveratrol may have potential therapeutic applications for prevention of diabetes-induced visual dysfunction.

Pubmed Data : Diabetes. 2010 Jul;59(7):1825-35. Epub 2010 Apr 27. PMID: 20424226
Article Published Date : Jul 01, 2010
Study Type : Animal Study
Additional Links
Substances : Resveratrol : CK(977) : AC(590)
Diseases : Diabetes: Cataract : CK(23) : AC(13), Diabetes: Visual Dysfunction : CK(2) : AC(1)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Apoptotic : CK(1489) : AC(1114), Enzyme Inhibitors : CK(372) : AC(208)
Additional Keywords : Stilbenes : CK(402) : AC(242)

"Antidepressant-like effect of trans-resveratrol in chronic stress model"

Pubmed Data : J Psychiatr Res. 2012 Nov 19. Epub 2012 Nov 19. PMID: 23174668
Article Published Date : Nov 18, 2012
Study Type : Animal Study
Additional Links
Substances : Resveratrol : CK(977) : AC(590)
Diseases : Depression : CK(674) : AC(88)
Pharmacological Actions : Antidepressive Agents : CK(142) : AC(31)

"Dietary Resveratrol Prevents Development of High-Grade Prostatic Intraepithelial Neoplastic Lesions."

Pubmed Data : Cancer Prev Res (Phila). 2012 Dec 17. Epub 2012 Dec 17. PMID: 23248098
Article Published Date : Dec 16, 2012
Study Type : Animal Study
Additional Links
Substances : Resveratrol : CK(977) : AC(590)
Diseases : High-Grade Prostatic Intraepithelial Neoplastic Lesions : CK(2) : AC(1), Prostate Cancer: Prevention : CK(155) : AC(16)
Pharmacological Actions : Chemopreventive : CK(1528) : AC(382)

"Effects of resveratrol on incisional wound healing in rats."

Pubmed Data : Surg Today. 2012 Dec 15. Epub 2012 Dec 15. PMID: 23242670
Article Published Date : Dec 14, 2012
Study Type : Animal Study
Additional Links
Substances : Resveratrol : CK(977) : AC(590)
Diseases : Wound Healing : CK(235) : AC(72)

"Resveratrol ameliorates ionizing irradiation-induced long-term hematopoietic stem cell injury in mice."

Pubmed Data : Free Radic Biol Med. 2012 Nov 1 ;54C:40-50. Epub 2012 Nov 1. PMID: 23124026
Article Published Date : Oct 31, 2012
Study Type : Animal Study
Additional Links
Substances : Resveratrol : CK(977) : AC(590)
Diseases : Radiation Induced Illness: Bone Marrow : CK(22) : AC(13)
Pharmacological Actions : Radioprotective : CK(456) : AC(183)

"Resveratrol prevents the wasting disorders of mechanical unloading by acting as a physical exercise mimetic in the rat."

Pubmed Data : FASEB J. 2011 Oct ;25(10):3646-60. Epub 2011 Jun 29. PMID: 21715682
Article Published Date : Oct 01, 2011
Study Type : Animal Study
Additional Links
Substances : Resveratrol : CK(977) : AC(590)
Diseases : Inflammation : CK(1077) : AC(363), Insulin Resistance : CK(1034) : AC(221), Space Flight Associated Adverse Changes : CK(2) : AC(1)
Pharmacological Actions : Enzyme Inhibitors : CK(372) : AC(208)

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