Rutin

Rutin

User Options

A Membership is required. Please Login or Create an account to get startedRequest us to build a Downloadable Document Product on this TopicMake a Request for GMI to add more Articles on this Topic Immediately (Purchase Required)View a Printer Friendly version of this pageE-mail this page to a friendPerform a Search with this Topic
Hover over an icon for more information

Additional Topics Details for this Page

  • - 30
  • - 95

View the Evidence: Substances

A combination of glucosamine sulfate, sodium hyaluronate, chondroitin sulfate, quercetin and rutin improve symptoms of interstitial cystitis/painful bladder syndrome.

Pubmed Data : J Agric Food Chem. 2008 Sep 24;56(18):8374-8. Epub 2008 Aug 30. PMID: 19046494
Article Published Date : Sep 24, 2008
Study Type : Human Study
Additional Links
Substances : Chondroitin Sulfate : CK(36) : AC(8), Glucosamine : CK(116) : AC(21), Hyaluronic Acid : CK(83) : AC(10), Quercetin : CK(318) : AC(136), Rutin : CK(93) : AC(30)
Diseases : Chronic Pelvic Pain Syndrome : CK(52) : AC(6), Cystitis: Interstitial : CK(32) : AC(4), Interstitial Cystitis : CK(136) : AC(17), Painful Bladder Syndrome : CK(20) : AC(2)

A high dose oral form of rutin significantly reduces pain and bleeding associated with hemorrhoid disease.

Pubmed Data : Minerva Med. 1986 Sep 29;77(37):1663-8. PMID: 3531924
Article Published Date : Sep 29, 1986
Study Type : Human Study
Additional Links
Substances : Rutin : CK(93) : AC(30)
Diseases : Hemorrhoids : CK(122) : AC(13)

Buckwheat herb tea protects against leg edemia in patients with chronic venous insufficiency.

Pubmed Data : Eur J Clin Pharmacol. 1996;50(6):443-7. PMID: 8858269
Article Published Date : Jan 01, 1996
Study Type : Human Study
Additional Links
Substances : Buckwheat : CK(48) : AC(16), Rutin : CK(93) : AC(30)
Diseases : Chronic Venous Insufficency : CK(73) : AC(12), Edema : CK(107) : AC(13), Leg Edema : CK(10) : AC(1), Venous Insufficiency : CK(51) : AC(4)
Additional Keywords : Plant Extracts : CK(3616) : AC(1226)

Quercetin and rutin may ameliorate insecticide induced oxidative stress in human erythrocytes.

Pubmed Data : Toxicol In Vitro. 2010 Mar;24(2):460-4. Epub 2009 Oct 13. PMID: 19833193
Article Published Date : Mar 01, 2010
Study Type : Human Study
Additional Links
Substances : Flavonoids : CK(909) : AC(289), Quercetin : CK(318) : AC(136), Rutin : CK(93) : AC(30)
Diseases : Oxidative Stress : CK(1945) : AC(710), Pesticide Toxicity : CK(147) : AC(45)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

Selected antioxidants have a protective effect against beta-cyfluthrin-induced oxidative stress in human erythrocytes in vitro.

Pubmed Data : Toxicol In Vitro. 2010 Apr;24(3):879-84. Epub 2009 Dec 2. PMID: 19961921
Article Published Date : Apr 01, 2010
Study Type : Human Study
Additional Links
Substances : Melatonin : CK(470) : AC(131), Quercetin : CK(318) : AC(136), Rutin : CK(93) : AC(30)
Diseases : Benzo[a]pyrene-induced Toxicity : CK(62) : AC(33), Oxidative Stress : CK(1945) : AC(710)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)

The topical application of rutin, vitamin E and an SPF 15 UVA-protective sunscreen has high clinical efficacy in Polymorphous Light Eruption.

Pubmed Data : Ann Dermatol Venereol. 2006 May;133(5 Pt 1):425-8. PMID: 16760827
Article Published Date : May 01, 2006
Study Type : Human Study
Additional Links
Substances : Rutin : CK(93) : AC(30), Vitamin E : CK(1285) : AC(221)
Diseases : Photodermatosis : CK(23) : AC(4), Photosensitivity Disorders : CK(24) : AC(4), Polymorphic Light Eruption (PMLE) : CK(22) : AC(3)

Allopurinol, quercetin and rutin ameliorate renal inflammasome activation and lipid accumulation in fructose-fed rats.

Pubmed Data : Biochem Pharmacol. 2012 Jul 1 ;84(1):113-25. Epub 2012 Mar 16. PMID: 22426011
Article Published Date : Jun 30, 2012
Study Type : Animal Study
Additional Links
Substances : Quercetin : CK(318) : AC(136), Rutin : CK(93) : AC(30)
Diseases : Dyslipidemias : CK(176) : AC(33), Fructose-Induced Toxicity : CK(138) : AC(49), Hyperuricemia : CK(253) : AC(32), Insulin Resistance : CK(1034) : AC(221)
Additional Keywords : Drug: Allopurinol : CK(6) : AC(3)
Problem Substances : Fructose : CK(356) : AC(103)

Consumption of some polyphenols reduces fecal deoxycholic acid and lithocholic acid, the secondary bile acids of risk factors of colon cancer.

Pubmed Data : J Agric Food Chem. 2009 Sep 23;57(18):8587-90. PMID: 19711910
Article Published Date : Sep 23, 2009
Study Type : Animal Study
Additional Links
Substances : Caffeic Acid : CK(15) : AC(11), Curcumin : CK(2923) : AC(1482), Ellagic Acid : CK(77) : AC(40), Flavonoids : CK(909) : AC(289), Polyphenols : CK(427) : AC(174), Rutin : CK(93) : AC(30)
Diseases : Colon Cancer : CK(895) : AC(233)
Pharmacological Actions : Anticarcinogenic Agents : CK(521) : AC(275)

Curcumin and rutin reduces colonic inflammation in multidrug resistant mice in a model of inflammatory bowel diseases.

Pubmed Data : Br J Nutr. 2009 Jan;101(2):169-81. Epub 2008 Sep 2. PMID: 18761777
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(2923) : AC(1482), Rutin : CK(93) : AC(30)
Diseases : Inflammatory Bowel Diseases : CK(1227) : AC(103)

Olive leaf contains phenolics with radioprotective properties.

Pubmed Data : J Hepatol. 1994 Jan;20(1):41-6. PMID: 12495584
Article Published Date : Jan 01, 1994
Study Type : Animal Study
Additional Links
Substances : Diosmin : CK(184) : AC(31), Flavonoids : CK(909) : AC(289), Olive leaf extract : CK(132) : AC(26), Rutin : CK(93) : AC(30)
Diseases : Radiation Induced Illness : CK(1018) : AC(249)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Radioprotective : CK(458) : AC(183)
Additional Keywords : Plant Extracts : CK(3616) : AC(1226)

Quercetin, curcumin, ginseng and rutin exhibit anti-cancer activity in an animal model of colon cancer.

Pubmed Data : Arch Neurol. 2003 Feb;60(2):194-200. PMID: 15831530
Article Published Date : Feb 01, 2003
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(2923) : AC(1482), Ginseng : CK(339) : AC(113), Quercetin : CK(318) : AC(136), Rutin : CK(93) : AC(30)
Diseases : Colon Cancer : CK(895) : AC(233), Colon Polyps : CK(42) : AC(12), Gastrointestinal polyps : CK(23) : AC(4)
Pharmacological Actions : Anticarcinogenic Agents : CK(521) : AC(275), Antioxidants : CK(3653) : AC(1318), Chemopreventive : CK(1528) : AC(382)
Additional Keywords : Plant Extracts : CK(3616) : AC(1226)

Rutin and quercetin attenuates hyperuricemia and renal dysfunction in rats induced by fructose intake.

Pubmed Data : Am J Physiol Renal Physiol. 2009 Oct;297(4):F1080-91. Epub 2009 Jul 15. PMID: 19605544
Article Published Date : Oct 01, 2009
Study Type : Animal Study
Additional Links
Substances : Quercetin : CK(318) : AC(136), Rutin : CK(93) : AC(30)
Diseases : Hyperuricemia : CK(253) : AC(32)
Additional Keywords : Natural Substances Versus Drugs : CK(988) : AC(165)

Rutin compares favorably to lovastatin in reducing the levels of total cholesterol, and LDL-C and also markedly decreased liver enzymes and weight in animals with a high-cholesterol diet.

Pubmed Data : Int J Oncol. 2008 Dec;33(6):1307-13. PMID: 19175365
Article Published Date : Dec 01, 2008
Study Type : Animal Study
Additional Links
Substances : Rutin : CK(93) : AC(30)
Diseases : High Cholesterol : CK(1718) : AC(198)
Pharmacological Actions : Anticholesteremic Agents : CK(669) : AC(142)
Additional Keywords : Natural Substances Versus Drugs : CK(988) : AC(165)

Rutin inhibits leukemia in mice and promotes an immune response.

Pubmed Data : Leuk Res. 2009 Jun;33(6):823-8. Epub 2008 Nov 17. PMID: 19010542
Article Published Date : Jun 01, 2009
Study Type : Animal Study
Additional Links
Substances : Rutin : CK(93) : AC(30)
Diseases : Leukemia : CK(670) : AC(258)
Pharmacological Actions : Antiproliferative : CK(1058) : AC(775), Immunomodulatory : CK(536) : AC(142)

Rutin inhibits nitric oxide and tumor necrosis factor-alpha production in lipopolysaccharide and concanavalin-a stimulated macrophages.

Pubmed Data : Drug Metabol Drug Interact. 2007;22(4):263-78. PMID: 18447002
Article Published Date : Jan 01, 2007
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(909) : AC(289), Rutin : CK(93) : AC(30)
Diseases : Lipopolysaccharide-Induced Toxicity : CK(227) : AC(128)
Pharmacological Actions : Nitric Oxide Inhibitor : CK(108) : AC(57), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(971) : AC(348)

Rutin prevents cognitive impairments by ameliorating oxidative stress and neuroinflammation in rat model of sporadic dementia of Alzheimer type.

Pubmed Data : Neuroscience. 2012 May 17 ;210:340-52. Epub 2012 Mar 6. PMID: 22441036
Article Published Date : May 16, 2012
Study Type : Animal Study
Additional Links
Substances : Rutin : CK(93) : AC(30)
Diseases : Brain Inflammation : CK(79) : AC(35), Inflammation : CK(1077) : AC(363), Oxidative Stress : CK(1945) : AC(710)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Neuroprotective Agents : CK(962) : AC(480)

Rutin protects the neural damage induced by transient focal ischemia in rats.

Pubmed Data : Brain Res. 2009 Oct 6;1292:123-35. Epub 2009 Jul 22. PMID: 19631195
Article Published Date : Oct 06, 2009
Study Type : Animal Study
Additional Links
Substances : Rutin : CK(93) : AC(30)
Diseases : Cerebral Ischemia : CK(263) : AC(50), Middle Cerebral Artery Occlusion (MCAO) : CK(592) : AC(24)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Apoptotic : CK(1535) : AC(1155), Neuroprotective Agents : CK(962) : AC(480), Tumor Suppressor Protein p53 Upregulation : CK(163) : AC(105)

Tetrahydrocurcumin and rutin have cardioprotective properties in a rat model of myocardial infarction

Pubmed Data : Pharmazie. 2009 Feb;64(2):132-6. PMID: 19320287
Article Published Date : Feb 01, 2009
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(2923) : AC(1482), Rutin : CK(93) : AC(30), Tetrahydrocurcumin : CK(37) : AC(20)
Diseases : Myocardial Infarction : CK(2632) : AC(117), Oxidative Stress : CK(1945) : AC(710)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Cardioprotective : CK(702) : AC(196)

The flavonoids tangeretin, rutin and especially diosmin inhibit the implantation, growth and invasion of metastatic melanoma.

Pubmed Data : J Agric Food Chem. 2005 Aug 24;53(17):6791-7. PMID: 16104801
Article Published Date : Aug 24, 2005
Study Type : Animal Study
Additional Links
Substances : Diosmin : CK(184) : AC(31), Rutin : CK(93) : AC(30), Tangeretin : CK(2) : AC(1)
Diseases : Melanoma: Metastatic : CK(21) : AC(13)

Buckwheat and especially buckwheat sprouts have significant antioxidant activity.

Pubmed Data : J Agric Food Chem. 2008 Jan 9;56(1):173-8. Epub 2007 Dec 12. PMID: 18072736
Article Published Date : Jan 09, 2008
Study Type : In Vitro Study
Additional Links
Substances : Buckwheat : CK(48) : AC(16), Rutin : CK(93) : AC(30), Sprouts : CK(76) : AC(36)
Diseases : Oxidative Stress : CK(1945) : AC(710)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318)
Additional Keywords : Plant Extracts : CK(3616) : AC(1226)

buckwheat extract has antioxidant and photoprotective properties.

Pubmed Data : Pharmazie. 2006 Mar;61(3):237-40. PMID: 16599267
Article Published Date : Mar 01, 2006
Study Type : In Vitro Study
Additional Links
Substances : Rutin : CK(93) : AC(30)
Diseases : Oxidative Stress : CK(1945) : AC(710), Skin Diseases: Photo-Aging : CK(365) : AC(47), Sunburn : CK(31) : AC(18)
Pharmacological Actions : Antioxidants : CK(3653) : AC(1318), Radioprotective : CK(458) : AC(183)
Additional Keywords : Plant Extracts : CK(3616) : AC(1226)

Fruits and vegetable consumption increases rutin metabolites which are novel inhibitors of nonoxidative advanced glycation end products.

Pubmed Data : Free Radic Biol Med. 2009 Dec 4. Epub 2009 Dec 4. PMID: 19969069
Article Published Date : Dec 04, 2009
Study Type : In Vitro Study
Additional Links
Substances : Fruit: All : CK(1836) : AC(472), Rutin : CK(93) : AC(30), Vegetables: All : CK(551) : AC(69)
Diseases : Advanced Glycation End products (AGE) : CK(2114) : AC(40)

Nutritional evaluation: Buckwheat.

Pubmed Data : J Agric Food Chem. 2006 Jul 26;54(15):5330-5. PMID: 16848513
Article Published Date : Jul 26, 2006
Study Type : In Vitro Study
Additional Links
Substances : Buckwheat : CK(48) : AC(16), Catechin : CK(403) : AC(130), Rutin : CK(93) : AC(30)

Quercetin and rutin protect against asbestos-induced disease.

Pubmed Data : Free Radic Biol Med. 1996;21(4):487-93. PMID: 8886799
Article Published Date : Jan 01, 1996
Study Type : In Vitro Study
Additional Links
Substances : Quercetin : CK(318) : AC(136), Rutin : CK(93) : AC(30)
Diseases : Asbestos Toxicity : CK(4) : AC(3), Oxidative Stress : CK(1945) : AC(710)

Rutin exhbits a protective effect against chemically-induced liver cancer.

Pubmed Data : Exp Toxicol Pathol. 2011 Jul ;63(5):459-65. Epub 2010 Apr 17. PMID: 20399630
Article Published Date : Jul 01, 2011
Study Type : In Vitro Study
Additional Links
Substances : Rutin : CK(93) : AC(30)
Diseases : Benzo[a]pyrene-induced Toxicity : CK(62) : AC(33), DNA damage : CK(711) : AC(293), Liver Cancer: Prevention : CK(109) : AC(21)
Pharmacological Actions : Antimutagenic Agents : CK(74) : AC(44), Antiproliferative : CK(1058) : AC(775), Apoptotic : CK(1535) : AC(1155), Chemopreventive : CK(1528) : AC(382)

Print Options

Some features are currently member only features. If you are already a member, please login. Otherwise, click here to become a member.