Saffron

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76 Diseases Researched for Saffron
NameACCKFocus
Depression653Locked
Erectile Dysfunction330Locked
Macular Degeneration321Locked
Sexual Dysfunction: SSRI-induced220Locked
Alzheimer's Disease413Locked
Depressive Disorder312Locked
Diabetes Mellitus: Type 2212Locked
Appetite Disorders110Locked
Diabetic Complications110Locked
Dysmenorrhea110Locked
High Cholesterol110Locked
Maculopathy: Age-Related110Locked
Overweight 110Locked
Premenstrual syndrome110Locked
Psoriasis110Locked
Weight Probems: Appetite 110Locked
Oxidative Stress48Locked
Chemotherapy-Induced Toxicity: Doxorubicin24Locked
Inflammation24Locked
Liver Cancer34Locked
Middle Cerebral Artery Occlusion (MCAO)24Locked
Anxiety Disorders23Locked
Colorectal Cancer23Locked
Hypertension23Locked
Neurodegenerative Diseases23Locked
Anorexia: Stress-Induced12Locked
Anxiety: Generalized12Locked
Brain: Oxidative Stress12Locked
Burns12Locked
Cancers: All22Locked
Cardiac Hypertrophy12Locked
Cerebral Ischemia12Locked
Chemotherapy-Induced Liver Toxicity12Locked
Chemotherapy-Induced Toxicity12Locked
Chemotherapy-Induced Toxicity: Cisplatin12Locked
DNA damage12Locked
Delayed Sleep Phase Disorder12Locked
Diabetic Neuropathy12Locked
Drug Toxicity: Isoprenaline12Locked
Excitotoxicity 12Locked
Insomnia12Locked
Kidney Diseases12Locked
Low Libido12Locked
Multiple Sclerosis12Locked
Neuropathic Pain12Locked
Opiate Addiction/Withdrawal12Locked
Pancreatic Cancer22Locked
Parkinson's Disease12Locked
Respiratory Diseases12Locked
Sleep Disorders12Locked
Tremor12Locked
Triglycerides: Elevated12Locked
Wound Healing12Locked
Acetaminophen (Tylenol) Toxicity 11Locked
Aluminum Toxicity 11Locked
Asthma11Locked
Breast Cancer11Locked
Bronchitis11Locked
Cadmium Poisoning 11Locked
Candida Infection 11Locked
Cervical Cancer11Locked
Chemical Poisoning: Accumulated Environmental Toxins11Locked
Common Cold11Locked
Coronary Artery Disease11Locked
Fever11Locked
Helicobacter Pylori Infection11Locked
Infertility11Locked
Leishmaniasis11Locked
Leukemia11Locked
Myocardial Ischemia11Locked
Pesticide Toxicity 11Locked
Plasmodium Infections11Locked
Schizophrenia11Locked
Skin Cancer11Locked
Asthenozoospermia10Locked
Infertility: Male10Locked
38 Pharmacological Actions Researched for Saffron
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View the Evidence:
63 Abstracts with Saffron Research

[+]
Pubmed Data : J Integr Med. 2013 Nov ;11(6):377-83. PMID: 24299602
Study Type : Meta Analysis
Additional Links
Substances : Saffron
Diseases : Depression
Pharmacological Actions : Antidepressive Agents
[+]
Pubmed Data : Nutr Res. 2010 May ;30(5):305-13. PMID: 20579522
Study Type : Human Study
Additional Links
Substances : Saffron
Additional Keywords : Phytotherapy, Plant Extracts
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Pubmed Data : Altern Med Rev. 2004 Sep;9(3):297-307. PMID: 15387720
Study Type : Human Study
Additional Links
Substances : Elm tree, Saffron
Diseases : Psoriasis
[+]
Pubmed Data : J Midwifery Womens Health. 2009 Sep-Oct;54(5):401-4. PMID: 19720342
Study Type : Human Study
Additional Links
Substances : Anise, Celery seed, Saffron
Diseases : Dysmenorrhea
[+]
Pubmed Data : J Evid Based Complementary Altern Med. 2015 May 6. Epub 2015 May 6. PMID: 25948674
Study Type : Human Study
Additional Links
Substances : Saffron
Additional Keywords : Significant Treatment Outcome
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Pubmed Data : J Ethnopharmacol. 2005 Feb 28 ;97(2):281-4. Epub 2005 Jan 6. PMID: 15707766
Study Type : Human Study
Additional Links
Substances : Saffron
Diseases : Depression
Pharmacological Actions : Antidepressive Agents
Problem Substances : Fluoxetine (trade name Prozac)
[+]
Pubmed Data : Hum Psychopharmacol. 2013 Jan ;28(1):54-60. Epub 2012 Dec 20. PMID: 23280545
Study Type : Human Study
Additional Links
Substances : Saffron
Additional Keywords : Plant Extracts
Problem Substances : Fluoxetine (trade name Prozac)
[+]
Pubmed Data : J Clin Pharm Ther. 2010 Oct ;35(5):581-8. PMID: 20831681
Study Type : Human Study
Additional Links
Substances : Saffron
Additional Keywords : Phytotherapy
[+]
Pubmed Data : J Affect Disord. 2014 Feb ;155:216-22. Epub 2013 Nov 16. PMID: 24289892
Study Type : Human Study
[+]
Pubmed Data : Psychopharmacology (Berl). 2010 Jan;207(4):637-43. Epub 2009 Oct 20. PMID: 19838862
Study Type : Human Study
Additional Links
Substances : Saffron
[+]
Pubmed Data : Phytomedicine. 2009 Aug;16(8):690-3. Epub 2009 May 9. PMID: 19427775
Study Type : Human Study
Additional Links
Substances : Saffron
[+]
Pubmed Data : Psychopharmacology (Berl). 2012 Oct ;223(4):381-8. Epub 2012 May 3. PMID: 22552758
Study Type : Human Study
Additional Links
Substances : Saffron
Additional Keywords : Plant Extracts
Problem Substances : Fluoxetine (trade name Prozac)
[+]
Pubmed Data : Acta Pharm. 2005 Dec;55(4):417-22. PMID: 18271889
Study Type : Human Study
Additional Links
Substances : Saffron
[+]
Pubmed Data : BMC Complement Altern Med. 2004 Sep 2;4:12. Epub 2004 Sep 2. PMID: 15341662
Study Type : Human Study
Additional Links
Substances : Saffron
Diseases : Depression
Additional Keywords : Natural Substances Versus Drugs
[+]
Pubmed Data : Arch Dis Child. 2009 Oct;94(10):801-5. Epub 2009 Jun 24. PMID: 18693099
Study Type : Human Study
Additional Links
Substances : Saffron
[+]
Pubmed Data : Invest Ophthalmol Vis Sci. 2010 Dec ;51(12):6118-24. Epub 2010 Aug 4. PMID: 20688744
Study Type : Human Study
Additional Links
Substances : Saffron
Additional Keywords : Phytotherapy
[+]
Pubmed Data : Rev Diabet Stud. 2014 Fall-Winter;11(3-4):258-66. Epub 2015 Feb 10. PMID: 26177486
Study Type : Human Study
Additional Links
Pharmacological Actions : Anticholesteremic Agents
Additional Keywords : Plant Extracts
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Basic Med Sci. 2015 May ;18(5):449-58. PMID: 26124930
Study Type : Animal Study
Additional Links
Substances : Saffron
Diseases : Tremor
[+]
Pubmed Data : Pharmazie. 2006 Apr;61(4):348-52. PMID: 16649553
Study Type : Animal Study
Additional Links
Pharmacological Actions : Antioxidants, Cardioprotective
[+]
Pubmed Data : Mol Nutr Food Res. 2012 Feb ;56(2):304-8. Epub 2011 Oct 28. PMID: 22038919
Study Type : Animal Study
Additional Links
Additional Keywords : Dose Response
[+]
Pubmed Data : Exp Oncol. 2007 Sep;29(3):175-80. PMID: 18004240
Study Type : Animal Study
Additional Links
Substances : Carotenoids, Saffron
Pharmacological Actions : Antiproliferative
Additional Keywords : Selective Cytotoxicity
[+]
Pubmed Data : Phytomedicine. 2009 Sep 9. Epub 2009 Sep 9. PMID: 19747807
Study Type : Animal Study
Additional Links
Substances : Saffron
Pharmacological Actions : Cardioprotective
[+]
Pubmed Data : Recent Pat Anticancer Drug Discov. 2015 Nov 1. Epub 2015 Nov 1. PMID: 26522014
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Crocin, Saffron
Diseases : Liver Cancer
[+]
Pubmed Data : J Agric Food Chem. 2009 Sep 23;57(18):8325-30. PMID: 19754168
Study Type : Animal Study
[+]
Pubmed Data : Biochim Biophys Acta. 2007 Apr;1770(4):578-84. Epub 2006 Dec 5. PMID: 17215084
Study Type : Animal Study
Additional Links
Substances : Carotenoids, Crocin, Saffron
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]
Pubmed Data : J Pharm Pharm Sci. 2005;8(3):387-93. Epub 2005 Aug 22. PMID: 16401388
Study Type : Animal Study
Additional Links
Substances : Carotenoids, Crocin, Saffron
Diseases : Kidney Diseases
[+]
Pubmed Data : Pak J Pharm Sci. 2015 Nov ;28(6):2095-9. PMID: 26639503
Study Type : Animal Study
[+]
Pubmed Data : Phytother Res. 2011 Dec ;25(12):1833-8. Epub 2011 Apr 19. PMID: 21503997
Study Type : Animal Study
Additional Links
Substances : Crocin, Saffron
Additional Keywords : Plant Extracts
[+]
Pubmed Data : Phytother Res. 2008 Mar;22(3):330-4. PMID: 18058985
Study Type : Animal Study
Additional Links
Substances : Saffron
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : An Acad Bras Cienc. 2014 Dec ;86(4):1821-32. Epub 2014 Dec 9. PMID: 25590719
Study Type : Animal Study
Additional Links
Substances : Saffron
Additional Keywords : Plant Extracts
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Adv Pharm Bull. 2014 Dec ;4(Suppl 2):493-9. Epub 2014 Dec 31. PMID: 25671180
Study Type : Animal Study
Additional Links
Substances : Crocin, Saffron
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts
[+]
Pubmed Data : Phytomedicine. 2008 Jun;15(6-7):491-5. Epub 2007 Oct 24. PMID: 17962007
Study Type : Animal Study
Additional Links
Substances : Carotenoids, Saffron
Diseases : Low Libido
Pharmacological Actions : Aphrodisiac
[+]
Pubmed Data : Phytother Res. 2009 Jun;23(6):768-74. PMID: 19142981
Study Type : Animal Study
Additional Links
Substances : Saffron
Pharmacological Actions : Anti-Anxiety Agents, Hypnotics and Sedatives
[+]
Pubmed Data : Phytother Res. 2009 Oct 13. Epub 2009 Oct 13. PMID: 19827024
Study Type : Animal Study
Additional Links
Substances : Saffron
[+]
Pubmed Data : J Nat Med. 2009 Sep 29. Epub 2009 Sep 29. PMID: 19787421
Study Type : Animal Study
Additional Links
Substances : Saffron
Diseases : Depression
Pharmacological Actions : Antidepressive Agents
[+]
Pubmed Data : Phytother Res. 2009 Dec 9. PMID: 20013822
Study Type : Animal Study
Additional Links
Substances : Saffron
Diseases : Hypertension
Pharmacological Actions : Hypotensive
[+]
Pubmed Data : Hum Exp Toxicol. 2006 Feb;25(2):79-84. PMID: 16539212
Study Type : Animal Study
Additional Links
Substances : Saffron
Pharmacological Actions : Chemopreventive, Chemotherapeutic
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Pubmed Data : Cell Mol Neurobiol. 2009 Aug 27. PMID: 19711182
Study Type : Animal Study
Additional Links
Substances : Saffron
[+]
Pubmed Data : Drug Chem Toxicol. 2015 Apr 17:1-10. Epub 2015 Apr 17. PMID: 25885550
Study Type : Animal Study
Additional Links
Substances : Saffron
Additional Keywords : Plant Extracts
[+]
Pubmed Data : Z Naturforsch C. 2014 Nov-Dec;69(11-12):459-70. PMID: 25854766
Study Type : Animal Study
Additional Links
Substances : Saffron
Additional Keywords : Plant Extracts
[+]
Pubmed Data : J Med Food. 2006;9(2):246-53. PMID: 16822211
Study Type : Animal Study
Additional Links
Substances : Saffron
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]
Pubmed Data : Pak J Biol Sci. 2009 May 1;12(9):690-5. PMID: 19634472
Study Type : Animal Study
Additional Links
Substances : Saffron
Pharmacological Actions : Antioxidants
[+]
Pubmed Data : Keio J Med. 2008 Dec;57(4):190-5. PMID: 19110531
Study Type : Animal Study
Additional Links
Substances : Saffron
Diseases : Burns, Wound Healing
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
Additional Keywords : Skin Regeneration
[+]
Pubmed Data : Neurotoxicology. 2015 Dec 17 ;52:230-242. Epub 2015 Dec 17. PMID: 26705857
Study Type : Insect Study
Additional Links
Substances : Crocin, Saffron
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]
Pubmed Data : Asia Pac J Clin Nutr. 2003;12(4):474-6. PMID: 14672873
Study Type : Animal Study
Additional Links
Substances : Saffron
Pharmacological Actions : Chemopreventive
Additional Keywords : Drug Side Effect Attenuation
[+]
Pubmed Data : J Pharm Pharmacol. 2006 Oct;58(10):1385-90. PMID: 17034662
Study Type : Animal Study
Additional Links
Substances : Saffron
Pharmacological Actions : Bronchodilator Agents
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Pubmed Data : Planta Med. 2008 Oct;74(12):1441-5. Epub 2008 Sep 24. PMID: 18816431
Study Type : Animal Study
Additional Links
Substances : Saffron, Safranal
Diseases : Excitotoxicity
Pharmacological Actions : Excitatory Amino Acid Agonists
[+]
Pubmed Data : Crit Rev Food Sci Nutr. 2015 Apr 15:0. Epub 2015 Apr 15. PMID: 25875654
Study Type : Review
Additional Links
Substances : Saffron
Pharmacological Actions : Cardioprotective, Neuroprotective Agents
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2016 ;21(3). Epub 2016 Mar 2. PMID: 26950102
Study Type : Review
Additional Links
Substances : Saffron
Pharmacological Actions : Anti-Anxiety Agents
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Basic Med Sci. 2015 May ;18(5):485-92. PMID: 26124935
Study Type : In Vitro Study
Additional Links
Substances : Saffron
Pharmacological Actions : Neuroprotective Agents
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2015 ;20(9):17570-84. Epub 2015 Sep 22. PMID: 26402666
Study Type : In Vitro Study
Additional Links
Substances : Crocetin, Crocin, Saffron
Diseases : Hypertension
Pharmacological Actions : Vasodilator Agents
Additional Keywords : Plant Extracts
[+]
Pubmed Data : Mol Cancer Ther. 2009 Feb;8(2):315-23. Epub 2009 Feb 10. PMID: 19208826
Study Type : In Vitro Study
Additional Links
Substances : Saffron
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Integr Med. 2015 Jul ;13(4):231-40. PMID: 26165367
Study Type : Review
Additional Links
Substances : Saffron
Additional Keywords : Significant Treatment Outcome
[+]
Pubmed Data : Rev Invest Clin. 2002 Sep-Oct;54(5):430-6. PMID: 12587418
Study Type : Commentary
Additional Links
Substances : Saffron
Diseases : Cancers: All
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Daru. 2015 ;23(1):31. Epub 2015 May 1. PMID: 25928729
Study Type : Review
[+]
Pubmed Data : Hepatology. 2011 Sep 2 ;54(3):857-67. Epub 2011 Jul 19. PMID: 21607999
Study Type : In Vitro Study
Additional Links
Substances : Saffron
Diseases : Liver Cancer
Additional Keywords : Plant Extracts
[+]
Pubmed Data : J Enzyme Inhib Med Chem. 2016 May 10:1-5. Epub 2016 May 10. PMID: 27160150
Study Type : In Vitro Study
Additional Links
Substances : Saffron
Pharmacological Actions : Antimicrobial
Additional Keywords : Natural Substance Synergy
[+]
Pubmed Data : CNS Neurol Disord Drug Targets. 2015 ;14(7):880-902. PMID: 25714974
Study Type : Review
Additional Links
Substances : Saffron
Pharmacological Actions : Neuroprotective Agents
[+]
Pubmed Data : J Enzyme Inhib Med Chem. 2015 Mar 13:1-7. Epub 2015 Mar 13. PMID: 25766747
Study Type : In Vitro Study
[+]
Pubmed Data : Phytother Res. 2016 Apr 21. Epub 2016 Apr 21. PMID: 27098287
Study Type : Review
[+]
Pubmed Data : J Tradit Complement Med. 2015 Apr ;5(2):81-7. Epub 2015 Jan 28. PMID: 26151016
Study Type : Review
Additional Links
Diseases : Cancers: All
Pharmacological Actions : Chemopreventive
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmacognosy Res. 2014 Apr ;6(2):99-107. PMID: 24761112
Study Type : Review
[+]
Pubmed Data : Urol J. 2008 Fall;5(4):255-9. PMID: 19101900
Additional Links
Substances : Saffron

Saffron Related Articles

Written by Pat Robinson
Kava is safe and effective in treating anxiety disorders and depression. L-tryptophan is as effective as imipramine in treating depression. Saffron may be of therapeutic benefit in the treatment of mild to moderate depression and has similar efficacy as the drug imipramine. St. John's Wort is as effective as Selective Serotoin Reuptake Inhibitors (SSRI) in the treatment of Depressive Disorder, with a greater safety rating.
As the baby-boomers age, blindness from age-related macular degeneration is on the rise. More than 3 million more people will become victims in the next five years. Eating right can lower your risk.
Age-related macular degeneration is on the rise. This ancient spice may save your sight.
Have you been inspired by this summer’s Olympic Games? Well, here’s the latest science on how natural supplements can safely improve your workout.
Saffron is again showing its healing abilities. Recent research finds it reduces heat shock protein antibodies and metabolic syndrome symptoms, along with stimulating immunity and cognition.
This exotic spice has been used to treat more than 90 illnesses over 4,000 years. Here are just 8 healthy reasons to use more saffron.
Low libido is a common complaint among women. It affects about 10% of women in the U.S., and up to 16% in Europe and Australia. Researchers are suggesting an ancient herb may provide relief.
Written by Sayer Ji, Founder
Did you know that so-called “incurable” neurodegenerative conditions such as Alzheimer’s disease can be slowed, if not also partially reversed?
Written by Sayer Ji, Founder
Clearly there is something magical about the Crocus sativus flower, from which the spice saffron is derived. If its striking beauty does not immediately cast a spell on its beholder, often it simply takes experiencing the spice to fall into full enchantment with it.

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