Saw Palmetto

Saw Palmetto

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View the Evidence: Substances

A combination of Saw Palmetto, Nettle, Curcumin and Quercetin significantly improves treatment outcome of prulifloxacin in bacterial prostatitis patients.

Pubmed Data : Int J Antimicrob Agents. 2009 Jun;33(6):549-53. Epub 2009 Jan 31. PMID: 19181486
Article Published Date : Jun 01, 2009
Study Type : Human Study
Additional Links
Substances : Curcumin : CK(2910) : AC(1482), Nettle : CK(44) : AC(13), Quercetin : CK(318) : AC(136), Saw Palmetto : CK(82) : AC(17)
Diseases : Prostatitis: Chronic : CK(327) : AC(11)
Additional Keywords : Drug-Plant-Vitamin Synergies : CK(1011) : AC(268)

A dietary supplement containing astaxanthin and saw palmetto berry extract decrease dihydrotestosterone, increase testosterone and decrease estradiol levels in healthy males.

Pubmed Data : J Cardiovasc Electrophysiol. 2009 Sep;20(9):1055-60. Epub 2009 Apr 30. PMID: 18700016
Article Published Date : Sep 01, 2009
Study Type : Human Study
Additional Links
Substances : Astaxanthin : CK(353) : AC(117), Saw Palmetto : CK(82) : AC(17)
Diseases : Low Testosterone : CK(385) : AC(70), Male Hormone Imbalances : CK(14) : AC(3), Testosterone: Too Low : CK(369) : AC(70)
Pharmacological Actions : Aromatase Inhibitors : CK(33) : AC(23)
Additional Keywords : DHT Blocker : CK(10) : AC(1)

An extract of saw palmetto compares favorably with the drug tamsulosin in the treatment of benign prostatic hyperplasia.

Pubmed Data : Prog Urol. 2002 Jun;12(3):384-92; discussion 394-4. PMID: 12189744
Article Published Date : Jun 01, 2002
Study Type : Human Study
Additional Links
Substances : Saw Palmetto : CK(82) : AC(17)
Diseases : Prostatic Hyperplasia: Benign : CK(202) : AC(46)
Pharmacological Actions : Adrenergic alpha-Antagonists : CK(11) : AC(2), Anti-Androgen : CK(58) : AC(15)
Additional Keywords : Drug: Tamsulosin : CK(20) : AC(2), Natural Substances Versus Drugs : CK(988) : AC(165), Plant Extracts : CK(3572) : AC(1216)

Saw palmetto (Serona repens) significantly reduces the clinical progression rates in men with mild symptoms of Bladder Outlet Obstruction.

Pubmed Data : Circulation. 1996 Nov 15;94(10):2369-72. PMID: 16175413
Article Published Date : Nov 15, 1996
Study Type : Human Study
Additional Links
Substances : Saw Palmetto : CK(82) : AC(17)
Diseases : Bladder Outlet Obstruction : CK(16) : AC(4), Urinary Flow Problems : CK(30) : AC(3), Urinary Retention : CK(20) : AC(2)

Saw palmetto compares favorably with the drug Flomax (tamsulosin) to alleviate benign prostatic hyperplasia (BPH).

Pubmed Data : Int Urol Nephrol. 2007;39(3):879-86. Epub 2007 Jan 4. PMID: 17203353
Article Published Date : Jan 01, 2007
Study Type : Human Study
Additional Links
Substances : Saw Palmetto : CK(82) : AC(17)
Diseases : Prostatic Hyperplasia: Benign : CK(202) : AC(46)
Additional Keywords : Drug: Tamsulosin : CK(20) : AC(2), Natural Substances Versus Drugs : CK(988) : AC(165), Plant Extracts : CK(3572) : AC(1216)

Saw palmetto inhibits 5-alpha reducatase activity in prostate cancer cell lines without interfering with PSA expression as is the case for pharmaceutical 5-alpha reductase inhibitors.

Pubmed Data : Clin Nutr. 2006 Dec;25(6):923-38. Epub 2006 May 11. PMID: 15543614
Article Published Date : Dec 01, 2006
Study Type : Human Study
Additional Links
Substances : Saw Palmetto : CK(82) : AC(17)
Diseases : Prostate Cancer : CK(998) : AC(288)
Pharmacological Actions : 5-alpha reductase inhibitor : CK(42) : AC(13)
Additional Keywords : Superiority of Natural Substances versus Drugs : CK(826) : AC(164)

The naturally occuring 5-alpha reductase inhibits Beta Sitosterol and Saw Palmetto are effective in treating androgenic alopecia.

Pubmed Data : J Altern Complement Med. 2002 Apr;8(2):143-52. PMID: 12006122
Article Published Date : Apr 01, 2002
Study Type : Human Study
Additional Links
Substances : Beta Sitosterol : CK(43) : AC(14), Saw Palmetto : CK(82) : AC(17)
Diseases : Alopecia: Androgenic : CK(23) : AC(8)
Pharmacological Actions : 5-alpha reductase inhibitor : CK(42) : AC(13)

Saw Palmetto (Serenoa repens) is more efficacious than Finasteride in inhibiting prostate enlargement.

Pubmed Data : Prostate. 2000 Apr 1;43(1):49-58.PMID:10725865
Article Published Date : Apr 01, 2000
Study Type : Animal Study
Additional Links
Substances : Saw Palmetto : CK(82) : AC(17)
Diseases : Prostatic Hyperplasia: Benign : CK(202) : AC(46)
Additional Keywords : Superiority of Natural Substances versus Drugs : CK(826) : AC(164)

Saw palmetto significantly alleviates urodynamic symptoms in hyperactive rat bladders.

Pubmed Data : J Urol. 2005 Apr;173(4):1395-9. PMID: 15758812
Article Published Date : Apr 01, 2005
Study Type : Animal Study
Additional Links
Substances : Saw Palmetto : CK(82) : AC(17)
Diseases : Lower Urinary Tract Symptoms : CK(12) : AC(2)
Additional Keywords : Improved Micturition : CK(2) : AC(1)

Astaxanthin and saw palmetto extract decrease the growth of prostatic cancer cells via 5-alpha reductase inhibition.

Pubmed Data : J Herb Pharmacother.2005;5(1):17-26. PMID: 16093232
 
Article Published Date : Jan 01, 2005
Study Type : In Vitro Study
Additional Links
Substances : Astaxanthin : CK(353) : AC(117), Saw Palmetto : CK(82) : AC(17)
Diseases : Prostate Cancer : CK(998) : AC(288)
Pharmacological Actions : 5-alpha reductase inhibitor : CK(42) : AC(13)

Saw palmetto (Serenoa repens) induces growth arrest and apoptosis of human multiple myeloma cells.

Pubmed Data : Oncol Rep. 2009 Aug;22(2):377-83. PMID: 19578780
Article Published Date : Aug 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Saw Palmetto : CK(82) : AC(17)
Diseases : Multiple Myeloma : CK(156) : AC(53)

Saw palmetto berry extract inhibits prostate cancer cell growth in part through Cox-2 enzyme inhibition.

Pubmed Data : Cell Biol Int.2001;25(11):1117-24. PMID: 11913955
Article Published Date : Jan 01, 2001
Study Type : In Vitro Study
Additional Links
Substances : Saw Palmetto : CK(82) : AC(17)
Diseases : Prostate Cancer : CK(998) : AC(288)
Pharmacological Actions : Cyclooxygenase 2 Inhibitors : CK(269) : AC(169)

Saw palmetto extract at clinically relevant doses may exert a direct effect on the pharmacological receptors in the lower urinary tract, thereby improving urinary dysfunction in patients with benign prostatic hyperplasia and an overactive bladder.

Pubmed Data : Life Sci. 2004 Apr 23;74(23):2897-908. PMID: 19262550
Article Published Date : Apr 23, 2004
Study Type : Commentary
Additional Links
Substances : Saw Palmetto : CK(82) : AC(17)
Diseases : Overactive Bladder : CK(105) : AC(13), Prostatic Hyperplasia: Benign : CK(202) : AC(46)
Pharmacological Actions : 5-alpha reductase inhibitor : CK(42) : AC(13), Adrenergic alpha-Antagonists : CK(11) : AC(2), Cholinergic Antagonists : CK(3) : AC(2)
Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Saw palmetto extract has a broad range of therapeutic pharmacological actions relevant to benign prostatic hyperplasia.

Pubmed Data : Biol Pharm Bull. 2009 Apr;32(4):646-50. PMID: 19336899
Article Published Date : Apr 01, 2009
Study Type : Review
Additional Links
Substances : Saw Palmetto : CK(82) : AC(17)
Diseases : Prostatic Hyperplasia: Benign : CK(202) : AC(46)
Pharmacological Actions : 5-alpha reductase inhibitor : CK(42) : AC(13), Adrenergic alpha-Agonists : CK(4) : AC(3), Calcium Channel Blockers : CK(86) : AC(21)

Saw palmetto has anticancer activity against a broad range of human cancer cell lines, with special efficacy against hormone-sensitive cancer cells.

Pubmed Data : Anticancer Res.2007 Mar-Apr;27(2):873-81. PMID: 17465214
Article Published Date : Mar 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Saw Palmetto : CK(82) : AC(17)
Diseases : Breast Cancer : CK(2354) : AC(621), Cancers: All : CK(9062) : AC(2869), Prostate Cancer : CK(998) : AC(288)

Saw palmetto induces programmed cell death in androgen-dependent prostate cancer cells.

Pubmed Data : Int J Oncol.2007 Sep;31(3):593-600. PMID: 17671686
Article Published Date : Sep 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Saw Palmetto : CK(82) : AC(17)
Diseases : Prostate Cancer : CK(998) : AC(288)

Saw palmetto induces programmed cell death in human prostate cancer cells.

Pubmed Data : BJU Int.2009 May;103(9):1275-83. Epub 2009 Jan 14 PMID: 19154468
Article Published Date : May 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Saw Palmetto : CK(82) : AC(17)
Diseases : Prostate Cancer : CK(998) : AC(288)

Related Blogs

Is Saw Palmetto Effective For Prostate Conditions?
Written by Case Adams, Naturopath
Having been shown effective as an herbal medicine for testicular conditions, prostate irritation and urination frequency problems for centuries in traditional medicine, numerous studies on Saw palmetto (Serenoa repens or Serenoa serrulata) for prostate conditions illustrated its effectiveness.

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